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A barium marking method using an ultrathin bronchoscope with virtual bronchoscopic navigation. | CT scanning in a 77-year-old woman showed a ground-glass opacity pattern shadow(9 x 7 mm) in the right lower lobe. To allow identification of the location of the lesion during thoracoscopic surgery, preoperative barium marking was performed using an ultrathin bronchoscope and virtual bronchoscopic navigation. Virtual b... | ['Aged', 'Barium', 'Bronchoscopy', 'Female', 'Fluoroscopy', 'Humans', 'Lung Diseases', 'Thoracoscopy', 'User-Computer Interface'] | 15,497,252 | [['M01.060.116.100'], ['D01.268.552.050', 'D01.268.556.062', 'D01.552.539.124', 'D01.552.544.062'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['E01.370.388.250.840', 'E04.502.250.840', 'E04.928... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Natural history of acute upper GI bleeding due to tumours: short-term success and long-term recurrence with or without endoscopic therapy. | BACKGROUND: Scant information is available regarding patients with upper gastrointestinal bleeding (UGIB) from tumours.AIM: To determine the presentation, endoscopic findings, treatment and outcomes in patients with UGIB from malignant tumours and identify risk factors associated with rebleeding.METHODS: Consecutive pa... | ['Aged', 'Blood Transfusion', 'Duodenal Neoplasms', 'Endoscopy, Gastrointestinal', 'Esophageal Neoplasms', 'Female', 'Gastrointestinal Hemorrhage', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Stomach Neoplasms', 'Time Factors'] | 23,710,797 | [['M01.060.116.100'], ['E02.095.135'], ['C04.588.274.476.411.445', 'C06.301.371.411.445', 'C06.405.249.411.445', 'C06.405.469.275.270', 'C06.405.469.491.445'], ['E01.370.372.250.250', 'E01.370.388.250.250.250', 'E04.210.240.250', 'E04.502.250.250.250'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impaired early- but not late-phase insulin secretion in subjects with impaired fasting glucose. | Subjects with impaired fasting glucose (IFG) are at increased risk for type 2 diabetes. We recently demonstrated that IFG subjects have increased hepatic insulin resistance with normal insulin sensitivity in skeletal muscle. In this study, we quantitated the insulin secretion rate from deconvolution analysis of the pla... | ['Adult', 'Blood Glucose', 'Fasting', 'Female', 'Glucose Clamp Technique', 'Glucose Intolerance', 'Glucose Tolerance Test', 'Humans', 'Insulin', 'Insulin Resistance', 'Insulin Secretion', 'Male', 'Metabolic Networks and Pathways', 'Middle Aged', 'Prediabetic State', 'Time Factors'] | 21,553,243 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['C18.452.394.952.500'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Concentration of ibuprofen in cervical mucus. | Concentrations of an acidic drug, ibuprofen, in cervical mucus and serum have been measured by HPLC after oral administration in six healthy volunteers. After an 800 mg single dose of ibuprofen, the concentration reached in cervical mucus was less than 4% of that in serum. It is postulated that because ibuprofen is an ... | ['Administration, Oral', 'Adult', 'Cervix Uteri', 'Chromatography, High Pressure Liquid', 'Female', 'Half-Life', 'Humans', 'Ibuprofen', 'Mucus'] | 1,672,904 | [['E02.319.267.100'], ['M01.060.116'], ['A05.360.319.679.256'], ['E05.196.181.400.300'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.223.701.430'], ['A12.200.503']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Epidemiology of diabetes mellitus in the fragility fracture population of a region of Southern Italy. | Increased risk of osteoporosis and its clinical significance in patients with diabetes is controversial. This study aims to increase the data which are available regarding the prevalence of diabetes mellitus in patients affected by fragility fracture in Italy. We retrospectively studied Hospital Discharge Data (HDD) in... | ['Aged', 'Aged, 80 and over', 'Diabetes Mellitus', 'Female', 'Fractures, Bone', 'Humans', 'Italy', 'Male', 'Middle Aged', 'Prevalence'] | 27,049,106 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C18.452.394.750', 'C19.246'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Accentuating the positive in adult attachments. | This paper proposes that attachment theory, with its emphasis on stability and security, accentuates the positive aspects of affectional relationships and suggests a way to look at the process of adult psychotherapy. Attachment-based research has shown that positive attachment experiences are related to feelings of joy... | ['Adult', 'Couples Therapy', 'Humans', 'Object Attachment', 'Psychological Theory', 'Psychotherapy', 'United States'] | 18,049,933 | [['M01.060.116'], ['F04.754.864.581.136'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.739.794.624'], ['F02.739'], ['F04.754'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
The effect of office visit copayments on utilization in a health maintenance organization. | This study estimated the impact of a $5 copayment on office visit rates in a health maintenance organization. A quasi-experimental design was used to compare the observed changes in visit rates by state government enrollees between the year before copayments and their first year of copayments with changes between the s... | ['Adolescent', 'Adult', 'Age Factors', 'Child', 'Child, Preschool', 'Deductibles and Coinsurance', 'Female', 'Health Maintenance Organizations', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Office Visits', 'Primary Health Care', 'Sex Factors', 'Washington'] | 2,586,186 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.151.170.300', 'N03.219.521.576.090.300'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Three different tyrosyl radicals identified in L-tyrosine HCl crystals upon gamma-irradiation: magnetic characterization and temporal evolution. | High-frequency electron paramagnetic resonance (EPR) and X-band electron-nuclear double resonance (ENDOR) spectroscopies were used to investigate the effect of gamma-irradiation on single crystals of L-tyrosine hydrochloride at room temperature. The oxidation product is the tyrosyl radical formed by hydrogen abstractio... | ['Crystallization', 'Free Radicals', 'Gamma Rays', 'Hydrochloric Acid', 'Magnetics', 'Models, Molecular', 'Molecular Conformation', 'Protons', 'Tyrosine'] | 18,318,523 | [['E05.196.300', 'G02.171'], ['D01.339', 'D02.389'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['D01.029.260.326', 'D01.210.450'], ['H01.671.493'], ['E05.599.595'], ['G02.111.570.820'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D12.125.072.050.875']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Results of whole-brain radiation as salvage of methotrexate failure for immunocompetent patients with primary CNS lymphoma. | PURPOSE: This study evaluates the efficacy and toxicity of whole-brain radiation therapy (WBRT) as salvage therapy for immunocompetent patients who failed initial high-dose methotrexate for primary CNS lymphoma (PCNSL).PATIENTS AND METHODS: The study cohort included 27 consecutive patients who failed initial high-dose ... | ['Antimetabolites, Antineoplastic', 'Brain', 'Brain Neoplasms', 'Disease-Free Survival', 'Female', 'Humans', 'Immunocompetence', 'Lymphoma, B-Cell', 'Male', 'Methotrexate', 'Middle Aged', 'Radiotherapy', 'Salvage Therapy', 'Survival Rate', 'Treatment Failure'] | 15,735,126 | [['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.15... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis, structure-activity relationships, and the effect of polyethylene glycol on inhibitors of phosphatidylinositol-specific phospholipase C from Bacillus cereus. | Substrate analog inhibitors of Bacillus cereus phosphatidylinositol-specific phospholipase C (PI-PLC) were synthesized and screened for their suitability to map the active site region of the enzyme by protein crystallography. Analogs of the natural substrate phosphatidylinositol (PI) were designed to examine the import... | ['Bacillus cereus', 'Crystallography, X-Ray', 'Enzyme Inhibitors', 'Isomerism', 'Micelles', 'Phosphatidylinositol Diacylglycerol-Lyase', 'Phosphoinositide Phospholipase C', 'Phosphoric Diester Hydrolases', 'Polyethylene Glycols', 'Protein Conformation', 'Structure-Activity Relationship'] | 8,893,831 | [['B03.300.390.400.158.218.252', 'B03.353.500.100.218.252', 'B03.510.100.100.218.252', 'B03.510.415.400.158.218.252', 'B03.510.460.410.158.218.252'], ['E05.196.309.742.225'], ['D27.505.519.389'], ['G02.111.570.685', 'G02.607.445'], ['D05.374', 'D26.255.560'], ['D08.811.277.352.640.700.700.500', 'D08.811.520.650.800'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Construction of some cytotoxic agents with aurone and furoaurone scaffolds. | AIM: In spite of the availability of different chemotherapies for cancer treatment, there is still a need for new candidates with higher efficacy and lower toxicity.METHODOLOGY: Aurones 7a-f, 8a-f and furoaurones 13a-f, 16a-c were synthesized. Some compounds were selected by the National Cancer Institute, USA, for cyto... | ['Antineoplastic Agents', 'Apoptosis', 'Benzofurans', 'Cell Line, Tumor', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Drug Screening Assays, Antitumor', 'Humans', 'Molecular Docking Simulation', 'Molecular Structure', 'Structure-Activity Relationship'] | 29,235,893 | [['D27.505.954.248'], ['G04.146.954.035'], ['D03.633.100.127'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Acute kidney injury in patients undergoing endovascular therapy for critical limb ischemia. | BACKGROUND: Similar to coronary angiography and interventions, patients undergoing percutaneous treatment of lower extremity peripheral arterial disease are also at risk of acute kidney injury (AKI). The incidence, risk factors associations, need for dialysis and inhospital mortality related to AKI in patients with cri... | ['Acute Kidney Injury', 'Aged', 'Aged, 80 and over', 'Critical Illness', 'Databases, Factual', 'Endovascular Procedures', 'Female', 'Hospital Mortality', 'Humans', 'Incidence', 'Ischemia', 'Lower Extremity', 'Male', 'Middle Aged', 'Peripheral Arterial Disease', 'Radiography, Interventional', 'Renal Dialysis', 'Risk Ass... | 31,419,029 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.291.625'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.100.814.529', 'E04.502.382'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400']... | ['Diseases [C]', 'Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Effects of divided attention on swallowing in healthy participants. | Swallowing impairments are treated mostly behaviorally. It is requisite to understand the relationship of cognition, specifically attention, with swallowing since so many swallowing impairments occur concomitantly with cognitive disorders. This study examined the hypothesis that attentional resources are required durin... | ['Acoustic Stimulation', 'Aged', 'Attention', 'Deglutition', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reaction Time', 'Time Factors'] | 21,892,783 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116.100'], ['F02.830.104.214'], ['G10.261.178'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The protective effect of microRNA-21 in neurons after spinal cord injury. | STUDY DESIGN: Experimental animal study.OBJECTIVES: To validate the anti-apoptosis effect of microRNA-21 in neurons after spinal cord injury (SCI) and explore the mechanism.SETTING: Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.METHODS: In situ hybridization was used to detect ... | ['Animals', 'Apoptosis', 'Apoptosis Regulatory Proteins', 'Cell Count', 'Disease Models, Animal', 'Hypoxia', 'Male', 'MicroRNAs', 'Motor Neurons', 'Oxygen', 'PC12 Cells', 'Phosphopyruvate Hydratase', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord Injuries', 'Transduction, Genetic', 'Transfection', 'Up-R... | 30,089,893 | [['B01.050'], ['G04.146.954.035'], ['D12.644.360.075', 'D12.776.476.075'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.888.852.079'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['A08.675.655.500', 'A11.671.655.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selected parameters of response organization in mildly mentally retarded children. | The purpose of this study was to investigate the effect of response organization on reaction time (RT) and movement time (MT) of mildly mentally retarded children. Two groups of 30 subjects each were formed: a retarded group 9 yr. of age and a normal group matched for chronological age. Subjects were randomly assigned ... | ['Child', 'Female', 'Functional Laterality', 'Humans', 'Intellectual Disability', 'Male', 'Psychomotor Performance', 'Reaction Time'] | 3,562,198 | [['M01.060.406'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Somatic and psychological effects of low-dose aromatase inhibition in men with obesity-related hypogonadotropic hypotestosteronemia. | INTRODUCTION: Reduced testosterone levels are frequently observed in obese men. Increased aromatase activity may be an etiological factor.OBJECTIVE: In this study, we evaluate the clinical effects of aromatase inhibition in obesity-related hypogonadotropic hypotestosteronemia (OrHH).METHODS: Double-blind, placebo-contr... | ['Adult', 'Androgens', 'Aromatase Inhibitors', 'Blood Glucose', 'Body Composition', 'Body Mass Index', 'Bone Density', 'Double-Blind Method', 'Energy Intake', 'Estradiol', 'Exercise Tolerance', 'Hormones', 'Humans', 'Hypogonadism', 'Letrozole', 'Lipid Metabolism', 'Luteinizing Hormone', 'Male', 'Middle Aged', 'Neuropsy... | 23,949,882 | [['M01.060.116'], ['D27.505.696.399.472.161'], ['D27.505.519.389.870.300', 'D27.505.696.399.450.327.149', 'D27.505.696.399.450.855.300'], ['D09.947.875.359.448.500'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.100'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[17â-estradiol protects against injury of aortic relaxation and contraction in ovariectomized rats with insulin resistance induced by fructose]. | The purpose of the present study was to investigate the effect of 17beta-estradiol (17beta-E(2)) on the structure and relaxation and contraction activity of thoracic aortas in ovariectomized rats with insulin resistance induced by fructose. Ovariectomized mature female Sprague-Dawley rats were fed with high fructose di... | ['Animals', 'Aorta', 'Estradiol', 'Female', 'Fructose', 'Insulin Resistance', 'Ovariectomy', 'Rats', 'Rats, Sprague-Dawley', 'Vasoconstriction', 'Vasodilation', 'Vasomotor System'] | 16,220,202 | [['B01.050'], ['A07.015.114.056'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.300.680'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Relationship between the expression of beta-cat, cyclin D1 and c-myc and the occurance and biological behavior of pancreatic cancer]. | OBJECTIVE: To study the relationship between the abnormal expression of beta-catenin (beta-cat) and the high expressions of cyclin D1 and c-myc and the occurance, proliferation, infiltration, metastasis and prognosis of pancreatic cancer, and to provide rational basis for the clinical diagnosis and treatment.METHODS: I... | ['Adult', 'Aged', 'Cyclin D1', 'Cytoskeletal Proteins', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Pancreas', 'Pancreatic Neoplasms', 'Proliferating Cell Nuclear Antigen', 'Proto-Oncogene Proteins c-myc', 'Trans-Activators', 'beta Catenin'] | 12,882,690 | [['M01.060.116'], ['M01.060.116.100'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['D12.776.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Childhood Sexual Abuse and Early Timing of Puberty. | PURPOSE: The purpose was to examine whether the timing of puberty, indexed by breast development and pubic hair development, was earlier for sexually abused females compared with a matched comparison group of nonabused females, controlling for key alternative confounds.METHODS: A cohort of sexually abused females and m... | ['Adolescent', 'Adult', 'Child', 'Cohort Studies', 'District of Columbia', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Puberty', 'Sex Offenses', 'Time', 'Young Adult'] | 27,836,531 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.107.567.875.500.210', 'Z01.433.429'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['G08... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A refined model of claudin-15 tight junction paracellular architecture by molecular dynamics simulations. | Tight-junctions between epithelial cells of biological barriers are specialized molecular structures that regulate the flux of solutes across the barrier, parallel to cell walls. The tight-junction backbone is made of strands of transmembrane proteins from the claudin family, but the molecular mechanism of its function... | ['Claudins', 'Computer Simulation', 'Crystallography, X-Ray', 'Humans', 'Hydrogen Bonding', 'Molecular Dynamics Simulation', 'Molecular Structure', 'Protein Conformation', 'Protein Domains', 'Protein Multimerization', 'Software', 'Solvents', 'Tight Junctions'] | 28,863,193 | [['D12.776.543.940.200'], ['L01.224.160'], ['E05.196.309.742.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.282'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570', 'G02.466'], ['G02.111.570.820.709'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['G02.111.694'... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The frequency of pharmacological pain relief in university neonatal intensive care units]. | OBJECTIVE: To evaluate the use of drugs to relieve procedural pain of newborn infants hospitalized in Neonatal Intensive Care Units (NICU) of university hospitals.METHODS: A prospective cohort study of all newborn infants hospitalized in four NICU during October 2001. The following data were collected: demographic data... | ['Analgesia', 'Analgesics', 'Birth Weight', 'Cohort Studies', 'Female', 'Fentanyl', 'Hospitals, University', 'Humans', 'Infant, Newborn', 'Intensive Care Units, Neonatal', 'Logistic Models', 'Male', 'Pain Measurement', 'Pain, Postoperative', 'Prospective Studies'] | 16,247,544 | [['E03.091'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D03.383.621.265'], ['N02.278.020.300... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of exacerbations in obstructive lung disease through biomarkers. | Inflammation has been identified as an important factor for disease exacerbation in obstructive lung disease. In this study, we used neutrophil and eosinophil counts as biomarkers for exacerbation in obstructive lung disease. We conducted a case-control study within a cohort of patients frequenting an outpatient clinic... | ['Adult', 'Aged', 'Asthma', 'Case-Control Studies', 'Disease Progression', 'Eosinophilia', 'Eosinophils', 'Female', 'Hospitalization', 'Humans', 'Leukocyte Count', 'Male', 'Middle Aged', 'Neutrophils', 'Odds Ratio', 'Pulmonary Disease, Chronic Obstructive', 'Severity of Illness Index'] | 19,863,191 | [['M01.060.116'], ['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.656'], ['C15.378.553.231'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis and evaluation of antitumor activity of arylamides and cyclohexylamides of isomeric 3-chloro-4-(2-chloroethylthio)butanoic- and 4-chloro-3-(2-chloroethylthio)butanoic acids. | In the hope to find antitumor candidates among di-(2-chloroethyl)sulfides it was found that only 3-chloro-4-(2-chloroethylthio)butanoic (3-chloro) and 4-chloro-3-(2-chloroethylthio)butanoic (4-chloro) acids possess definite alkylating ability which is suggested to be a reason of their high antitumor activity. However, ... | ['Amides', 'Animals', 'Antineoplastic Agents, Alkylating', 'Drug Screening Assays, Antitumor', 'Isomerism', 'Lethal Dose 50', 'Magnetic Resonance Spectroscopy', 'Mice', 'Mice, Inbred Strains', 'Rats', 'Rats, Wistar', 'Tumor Cells, Cultured'] | 9,079,243 | [['D02.065'], ['B01.050'], ['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['G02.111.570.685', 'G02.607.445'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['E05.196.867.519'], ['B01.050... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans. | OBJECTIVE: To study the association between cytochrome P450 2A6 (CYP2A6) genotype and metabolism of nicotine to cotinine, identify functional polymorphisms, and develop a predictive genetic model of nicotine metabolism.METHODS: The conversion of deuterated (D2)-nicotine to D2-cotinine was quantified in 189 European-Ame... | ['Alleles', 'Aryl Hydrocarbon Hydroxylases', 'Cotinine', 'Cytochrome P-450 CYP2A6', 'European Continental Ancestry Group', 'Female', 'Genetic Variation', 'Humans', 'Male', 'Middle Aged', 'Nicotine', 'Polymorphism, Genetic', 'Polymorphism, Single Nucleotide', 'Smoking'] | 21,597,399 | [['G05.360.340.024.340.030'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['D03.383.773.812.180'], ['D08.244.453.491.250', 'D08.811.682.690.708.170.450.250', 'D12.776.422.220.453.491.250'], ['M01.686.508.400'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.11... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
What aspects of human alcohol use disorders can be modeled using selectively bred rat lines? | The use of selective breeding to produce animal models for the study of alcohol abuse and alcoholism represents one of the major advances in the field of alcohol research. Rats selectively bred for alcohol preference and alcohol nonpreference have been useful to both preclinical and clinical investigators in the alcoho... | ['Alcoholism', 'Animals', 'Humans', 'Models, Animal', 'Rats', 'Rats, Inbred Strains', 'Translational Medical Research'] | 20,590,397 | [['C25.775.100.250', 'F03.900.100.350'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.598'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['H01.770.644.145.675']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Exercise testing provides additional prognostic information in angiographically defined subgroups of patients with coronary artery disease. | We examined whether exercise testing with measurement of cardiac output during maximal exercise can provide additional prognostic information for medically treated patients in whom left ventricular function and extent of coronary artery disease are known. We followed 1034 patients with normal or mildly impaired left ve... | ['Angiography', 'Cardiac Output', 'Coronary Angiography', 'Coronary Disease', 'Exercise Test', 'Female', 'Follow-Up Studies', 'Heart Rate', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Physical Exertion', 'Prognosis', 'Pulmonary Wedge Pressure', 'Time Factors'] | 6,616,799 | [['E01.370.350.700.060', 'E01.370.370.050'], ['E01.370.370.380.150', 'G09.330.380.124'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E05.318.372.500.750.249', 'N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The unrecognized extragonadal germ cell cancer syndrome. | Within 3 years we saw 12 patients diagnosed initially as having poorly differentiated or undifferentiated carcinomas who, we believe, actually had extragonadal germinal cancers. Serum levels of the beta subunit of human chorionic gonadotropin (beta-HCG) or alpha-fetoprotein were useful in suggesting and supporting the ... | ['Adult', 'Carcinoma', 'Chorionic Gonadotropin', 'Diagnosis, Differential', 'Female', 'Germ Cells', 'Humans', 'Lung Neoplasms', 'Male', 'Mediastinal Neoplasms', 'Middle Aged', 'Neoplasms', 'Syndrome', 'alpha-Fetoproteins'] | 6,162,409 | [['M01.060.116'], ['C04.557.470.200'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['E01.171'], ['A05.360.490', 'A11.497'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.588.894.479', 'C08.846.187.580'], ['M01.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Accuracy of diagnosis of salivary gland tumors with the use of ultrasonography, computed tomography, and magnetic resonance imaging: a meta-analysis. | OBJECTIVE: To compare ultrasonography (US), computed tomography (CT), and magnetic resonance imaging (MRI) for clinical differential diagnosis in patients with salivary gland tumor (SGT).STUDY DESIGN: Six databases were used to search the literature published between 1982 and 2013. Histologic diagnosis was required as ... | ['Humans', 'Magnetic Resonance Imaging', 'Salivary Gland Neoplasms', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 25,577,417 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.588.443.591.824', 'C07.465.530.824', 'C07.465.815.718'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ['E01.370.350.350.810', 'E01.370.350.60... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Arterial hypertension and cardiac decompensation]. | Treatment of high blood pressure has considerably postponed the development of heart failure in these patients. The repercussions of high blood pressure on the heart first consist in diastolic dysfunction of the left ventricule and then in the development of left ventricular hypertrophy. Diuretics and angiotensin conve... | ['Adrenergic beta-Antagonists', 'Angiotensin-Converting Enzyme Inhibitors', 'Antihypertensive Agents', 'Calcium Channel Blockers', 'Diuretics', 'Heart Failure', 'Humans', 'Hypertension'] | 8,927,860 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['D27.505.519.389.745.085'], ['D27.505.954.411.162'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D27.505.696.560.500'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
N-terminal brain natriuretic peptide predicted cardiovascular events stronger than high-sensitivity C-reactive protein in hypertension: a LIFE substudy. | BACKGROUND: N-terminal pro-brain natriuretic peptide (Nt-proBNP) and high-sensitivity C-reactive protein (hsCRP) are cardiovascular risk markers in various populations, but are not well examined in hypertension. Therefore, we wanted to investigate whether high Nt-proBNP or hsCRP predicted the composite endpoint of card... | ['Aged', 'Aged, 80 and over', 'Albumins', 'Antihypertensive Agents', 'Atenolol', 'Biomarkers', 'C-Reactive Protein', 'Cardiovascular Diseases', 'Confounding Factors, Epidemiologic', 'Creatinine', 'Endpoint Determination', 'Female', 'Follow-Up Studies', 'Humans', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Losarta... | 16,877,955 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.034'], ['D27.505.954.411.162'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C14'], ['N05.715.350.240', 'N06.850.490.718'], ['D03.383.129.308.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Efficient method for preparation of highly purified lipopolysaccharides by hydrophobic interaction chromatography. | A method for the efficient preparation of highly purified lipopolysaccharides (LPSs) by hydrophobic interaction chromatography (HIC) has been developed. The procedure can be used for the purification of cell wall bound LPSs after hot phenol-water extraction and for the isolation of extracellular LPSs from the supernata... | ['Cell Wall', 'Chromatography, Liquid', 'Escherichia coli', 'Lipopolysaccharides', 'Pseudomonas aeruginosa', 'Ultracentrifugation'] | 10,517,220 | [['A11.284.183'], ['E05.196.181.400'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['E05.181.724', 'E05.196.941']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alterations in the sensing and transport of phosphate and calcium by differentiating chondrocytes. | During endochondral bone formation and fracture healing, cells committed to chondrogenesis undergo a temporally restricted program of differentiation that is characterized by sequential changes in their phenotype and gene expression. This results in the manufacture, remodeling, and mineralization of a cartilage templat... | ['Alkaline Phosphatase', 'Animals', 'Blotting, Southern', 'Bone Development', 'Calcium', 'Cell Differentiation', 'Cell Line', 'Chondrocytes', 'Collagen', 'Hydrogen-Ion Concentration', 'Immunoblotting', 'Kidney', 'Parathyroid Glands', 'Parathyroid Hormone-Related Protein', 'Phenotype', 'Phosphates', 'Protein Transport',... | 11,404,353 | [['D08.811.277.352.650.035'], ['B01.050'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.152'], ['A11.251.210'], ['A11.329.171'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G02.300'], ['E... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo. | The widespread use of clomiphene citrate and exogenous gonadotrophins for in vitro fertilization (IVF) in human frequently results in the production of multiple embryos. Replacement of more than two embryos increases pregnancy rate but may result in multiple pregnancies with increased pre- and post-natal abnormality. P... | ['Bacterial Infections', 'Dimethyl Sulfoxide', 'Embryo Transfer', 'Female', 'Fertilization in Vitro', 'Fetal Death', 'Fetal Membranes, Premature Rupture', 'Freezing', 'Humans', 'Parental Consent', 'Pregnancy', 'Risk Assessment', 'Streptomyces', 'Tissue Preservation'] | 6,633,637 | [['C01.150.252'], ['D02.886.640.150'], ['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.750', 'E05.820.800.750'], ['C13.703.223', 'C23.550.260.585'], ['C13.703.420.339'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583.427.635.500', 'N03.706... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Epigenetic modifications by inhibiting histone deacetylases reverse memory impairment in insulin resistance induced cognitive deficit in mice. | Insulin resistance has been reported as a strong risk factor for Alzheimer's disease. However the molecular mechanisms of association between these still remain elusive. Various studies have highlighted the involvement of histone deacetylases (HDACs) in insulin resistance and cognitive deficits. Thus, the present study... | ['Animals', 'Avoidance Learning', 'Behavior, Animal', 'Brain-Derived Neurotrophic Factor', 'Cognition Disorders', 'Diet, High-Fat', 'Enzyme Inhibitors', 'Epigenesis, Genetic', 'Hippocampus', 'Histone Deacetylase Inhibitors', 'Histones', 'Hydroxamic Acids', 'Insulin Resistance', 'Male', 'Memory Disorders', 'Mice', 'Moto... | 26,805,421 | [['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F01.145.113'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['F03.615.250'], ['G07.203.650.240.267'], ['D27.505.519.389'], ['G05.308.203'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D27.505.519.3... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of transfection manipulations on mouse cell cycle progression. | BalB/C-3T3 mouse fibroblasts and a temperature-sensitive derivative, ts 2e, were transfected by the calcium phosphatedimethyl sulphoxide procedure to examine the effect of this manipulation on cell cycle progression. Cells were synchronized by growth to confluence in the presence of [2-14C]thymidine to generally label ... | ['3T3 Cells', 'Animals', 'Calcium Phosphates', 'Cell Cycle', 'DNA', 'Dimethyl Sulfoxide', 'Mice', 'Plasmids', 'Thymidine', 'Transfection'] | 1,793,569 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['G04.144'], ['D13.444.308'], ['D02.886.640.150'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.360.600'], ['D03.383.742.680.705', 'D13.570.230.855', 'D13.570.685.705'], ['E05.393.350.8... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnosis of Enterocytozoon bieneusi (microsporidia) infections by polymerase chain reaction in stool samples using primers based on the region coding for small-subunit ribosomal RNA. | OBJECTIVE: Enterocytozoon bieneusi is the most prevalent microsporidian causing chronic diarrhea in patients with acquired immunodeficiency syndrome. The current methods used for routine diagnosis of infections caused by microsporidia are based on microscopic detection of the microorganism spores in stained smears. We ... | ['Animals', 'Base Sequence', 'DNA Primers', 'DNA, Protozoan', 'Electrophoresis, Agar Gel', 'Feces', 'Fixatives', 'Formaldehyde', 'Humans', 'Intestinal Diseases, Parasitic', 'Microsporida', 'Microsporidiosis', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'RNA, Ribosomal'] | 9,278,618 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.442'], ['E05.196.401.153', 'E05.301.300.100'], ['A12.459'], ['D27.720.355'], ['D02.047.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.432', 'C06.405.469.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function. | OBJECTIVE: To investigate the effect of 4 weeks of treatment with liraglutide on insulin dose and glycemic control in type 1 diabetic patients with and without residual â-cell function.RESEARCH DESIGN AND METHODS: Ten type 1 diabetic patients with residual â-cell function (C-peptide positive) and 19 without (C-peptide ... | ['Adolescent', 'Adult', 'Blood Glucose', 'C-Peptide', 'Diabetes Mellitus, Type 1', 'Exercise Test', 'Female', 'Glucagon-Like Peptide 1', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Insulin-Secreting Cells', 'Liraglutide', 'Male', 'Middle Aged', 'Weight Loss'] | 21,593,296 | [['M01.060.057'], ['M01.060.116'], ['D09.947.875.359.448.500'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['D06.472.317.680.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preliminary results of the Sheehan total knee prosthesis. | A review of 50 knees in 42 patients operated upon between August, 1973 and November, 1976 is presented. Following initial good results, problems have been encountered with the passage of time. Complications due to design faults, selection, and technical pitfalls are analysed. Patients who have grossly unstable and defo... | ['Adult', 'Aged', 'Female', 'Humans', 'Joint Dislocations', 'Knee Prosthesis', 'Male', 'Middle Aged', 'Patella', 'Recurrence'] | 7,399,783 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['E07.695.400.410'], ['M01.060.116.630'], ['A02.835.232.043.650.624', 'A02.835.232.730.500'], ['C23.550.291.937']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Subchronic fluoxetine treatment induces a transient potentiation of amphetamine-induced hyperlocomotion: possible pharmacokinetic interaction. | The results of the present study show that 5 days of systemic treatment with fluoxetine (5 mg/kg) resulted in an augmented locomotor response to amphetamine (0.5 mg/kg). This augmented response to amphetamine was observed 24 and 48 h, but not 5 days, after the cessation of fluoxetine treatment. Subchronic fluoxetine tr... | ['Amphetamine', 'Animals', 'Brain', 'Central Nervous System Stimulants', 'Drug Synergism', 'Fluoxetine', 'Male', 'Motor Activity', 'Rats', 'Rats, Wistar', 'Serotonin Uptake Inhibitors', 'Stimulation, Chemical'] | 10,877,115 | [['D02.092.471.683.152.110'], ['B01.050'], ['A08.186.211'], ['D27.505.696.282', 'D27.505.954.427.220'], ['G07.690.773.968.477'], ['D02.092.831.280'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D27.505.519.562.437.850', 'D27.505.519... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway. | Somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin (Ig) genes are initiated by the enzymatic deamination of cytosine (C) to uracil (U). Uracil-DNA-glycosylase (Ung2) converts uracils into apyrimidinic (AP) sites, which is essential for the generation of transversions (TVs) at G/C basepai... | ['Animals', 'B-Lymphocytes', 'Base Composition', 'Cells, Cultured', 'Cytosine', 'DNA Breaks', 'DNA-Directed DNA Polymerase', 'Deamination', 'Guanine', 'Immunoglobulin Class Switching', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Nucleotidyltransferases', 'Somatic Hypermutation, Immunoglobulin', 'Uracil', 'Uracil-D... | 23,857,323 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G02.111.080'], ['A11.251'], ['D03.383.742.698.421'], ['G05.200.210'], ['D08.811.913.696.445.308.300'], ['G02.111.192', 'G02.607.157', 'G03.222'], ['D03.633.100.759.758.399.454'], ['G0... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Palliative Care and Communication Training in Neurosurgery Residency: Results of a Trainee Survey. | OBJECTIVE: Neurosurgeons care for critically ill patients near the end of life, yet little is known about how well their training prepares them for this role. We surveyed a random sample of neurosurgery residents to describe the quantity and quality of teaching activities related to serious illness communication and pa... | ['Adult', 'Communication', 'Female', 'Health Care Surveys', 'Humans', 'Internship and Residency', 'Male', 'Neurosurgery', 'Palliative Care'] | 31,239,231 | [['M01.060.116'], ['F01.145.209', 'L01.143'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['H02.403.810.425'], ['E02.760.666', 'N02.421.585.666']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
The interaction of imposed and inherent olfactory mucosal activity patterns and their composite representation in a mammalian species using voltage-sensitive dyes. | From amphibian data, two mechanisms that could underlie the encoding of odorants by the mucosal activity patterns they engender are as follows (1) receptors with similar odorant selectivities could be aggregated spatially on the mucosa (inherent patterns); (2) in analogy to gas chromatography, as odorants are drawn alo... | ['Animals', 'Brain Mapping', 'Electric Stimulation', 'Fluorescent Dyes', 'Male', 'Mammals', 'Microscopy, Fluorescence', 'Olfactory Mucosa', 'Olfactory Pathways', 'Rats', 'Rats, Inbred Strains'] | 8,613,801 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E05.723.402'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649'], ['E01.370.350.515.458', 'E05.595.458'], ['A04.531.520.573', 'A04.760.600.640', 'A09.531.623', 'A10.615.550.760.600.640'], ['A08.186.211.180.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ceramic composites for biomedical applications. | Ceramics have been successfully used for more than twenty years for orthopaedic prostheses, as articulating bearing surfaces against ceramic or polymer components. In both cases, ceramics are characterized by low friction coefficient and low wear rate, compared to metallic materials (stainless steels, titanium and chr... | ['Aluminum', 'Ceramics', 'Hardness', 'Humans', 'Materials Testing', 'Prostheses and Implants', 'Surface Properties', 'Tensile Strength', 'Zirconium'] | 10,171,689 | [['D01.268.557.050', 'D01.552.547.050'], ['J01.637.153'], ['G01.374.647'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['E07.695'], ['G02.860'], ['G01.374.850'], ['D01.268.556.950', 'D01.268.956.937', 'D01.552.544.950']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Simultaneous determination of five sex hormones in human serum by radioimmunoassay after chromatography on Lipidex-5000. | We describe a method for determination of pregnenolone, progesterone, 17alpha-hydroxyprogesterone, testosterone, and 5alpha-dihydrotestosterone in 1-2 ml of serum from male or female. Using microcolumns of Lipidex-5000 (hydroxyalkoxypropyl Sephadex, 0.5 g) and light petroleum/chloroform (97/3) as the solvent during chr... | ['Antibody Specificity', 'Chromatography, Gel', 'Contraceptives, Oral', 'Dihydrotestosterone', 'Female', 'Humans', 'Hydroxyprogesterones', 'Male', 'Menstruation', 'Microchemistry', 'Pregnenolone', 'Progesterone', 'Progestins', 'Radioimmunoassay', 'Testosterone'] | 1,245,058 | [['G12.100'], ['E05.196.181.400.250'], ['D27.505.696.875.360.276.210', 'D27.505.954.705.360.276.210'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.829.395', 'D06.472.334.851.687.750.478'], ['G08.686.605.428'], ['E05.196.620', 'H01.18... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of local cooling on sweating rate and cold sensation. | Subjects resting in a 39 degrees C environment were stimulated in different skin regions with a water cooled thermode. This local cooling produced decreases in sweating rate measured at the thigh and increases in magnitude estimates of the cold sensation. The are of cold stimulation varied from 111 cm2 to 384 cm2. Sens... | ['Abdomen', 'Autonomic Nervous System', 'Back', 'Body Temperature Regulation', 'Cold Temperature', 'Face', 'Humans', 'Leg', 'Male', 'Secretory Rate', 'Skin', 'Skin Physiological Phenomena', 'Skin Temperature', 'Sweating', 'Thermoreceptors', 'Thermosensing', 'Thigh', 'Thorax', 'Time Factors'] | 1,169,755 | [['A01.923.047'], ['A08.800.050'], ['A01.923.176'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Financial Implications of Physician Specialty Choice. | PURPOSE: To examine the approximated financial outcomes of physicians by specialty and to determine whether these correlate with mean USMLE Step 1 scores.METHODS: Specialty-specific data from the Association of American Medical Colleges Careers in Medicine website were analyzed for total length of training, mean USMLE ... | ['Career Choice', 'Educational Measurement', 'Humans', 'Licensure, Medical', 'Medicine', 'Neurosurgery', 'Physicians', 'Retirement', 'Salaries and Fringe Benefits', 'United States'] | 30,278,604 | [['F02.463.785.373.346.400'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.110.510.410', 'N05.700.200.450.500'], ['H02.403'], ['H02.403.810.425'], ['M01.526.485.810', 'N02.360.810'], ['I03.702'], ['N01.824.417.700', 'N04.452.677.800'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Clinical course and short-term outcome of postsplenectomy reactive thrombocytosis in children without myeloproliferative disorders: A single institutional experience from a developing country. | OBJECTIVES: To evaluate the clinical outcome and complications in the pediatric population who had splenectomy at our institution, emphasizing the incidence of postplenectomy reactive thrombocytosis (RT) and its clinical significance in children without underlying hematological malignancies.MATERIALS AND METHODS: The m... | ['Adolescent', 'Child', 'Child, Preschool', 'Developing Countries', 'Female', 'Humans', 'Incidence', 'Length of Stay', 'Leukocyte Count', 'Male', 'Myeloproliferative Disorders', 'Platelet Count', 'Postoperative Complications', 'Postoperative Period', 'Purpura, Thrombocytopenic, Idiopathic', 'Retrospective Studies', 'Sp... | 32,756,575 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['I01.615.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E02.760.400.480', 'N02.421.585.400.480'], ['E01.370.225.500.195.107.595', 'E01... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Adapting cognitive diagnosis computerized adaptive testing item selection rules to traditional item response theory. | Currently, there are two predominant approaches in adaptive testing. One, referred to as cognitive diagnosis computerized adaptive testing (CD-CAT), is based on cognitive diagnosis models, and the other, the traditional CAT, is based on item response theory. The present study evaluates the performance of two item selec... | ['Algorithms', 'Bayes Theorem', 'Bias', 'Cognition', 'Computer Simulation', 'Computers', 'Data Accuracy', 'Educational Measurement', 'Humans', 'Psychometrics'] | 31,923,227 | [['G17.035', 'L01.224.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['N05.715.350.150', 'N06.850.490.500'], ['F02.463.188'], ['L01.224.160'], ['L01.224.230.260'], ['E05.318.308.028', 'E05.318.370.725.250', 'L01.399.250.202', 'N05.715.360.300.202', 'N05.715.360.325.685.250'], ['I0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Quantitative analysis of gemcitabine triphosphate in human peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry. | Gemcitabine triphosphate (dFdCTP) is a highly active metabolite of gemcitabine. It is formed intra-cellularly via the phosphorylation of gemcitabine by deoxycytidine kinase. The monitoring of dFdCTP in human peripheral blood mononuclear cells (PBMCs), in addition to plasma concentrations of gemcitabine and its metaboli... | ['Anions', 'Antimetabolites, Antineoplastic', 'Calibration', 'Chromatography, Liquid', 'Deoxycytidine', 'Humans', 'Leukocyte Count', 'Leukocytes, Mononuclear', 'Proteins', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tandem Mass Spectrometry'] | 17,117,372 | [['D01.248.497.158'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['E05.978.155'], ['E05.196.181.400'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Identification of a novel fusion gene, IRF2BP2-RARA, in acute promyelocytic leukemia. | Acute promyelocytic leukemia (APL) is characterized by the fusion of retinoic acid receptor alpha (RARA) with promyelocytic leukemia (PML) or, rarely, other gene partners. This report presents a patient with APL with a novel fusion between RARA and the interferon regulatory factor 2 binding protein 2 (IRF2BP2) genes. A... | ['Bone Marrow', 'Carrier Proteins', 'Chromosomes, Human, Pair 1', 'Chromosomes, Human, Pair 17', 'DNA-Binding Proteins', 'Female', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Leukemia, Promyelocytic, Acute', 'Nuclear Proteins', 'Oncogene Proteins, Fusion', 'Receptors, Retinoic Acid', 'Retinoic Acid Receptor alp... | 25,583,766 | [['A15.382.216'], ['D12.776.157'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240'], ['A11.284.187.520.300.415.425', 'G05.360.162.520.300.415.425'], ['D12.776.260'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275.700'], ['D12.776.660'], ['D12.776.602.500.500', ... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Micellar electrokinetic chromatographic screening method for common sexual assault drugs administered in beverages. | Recently, much attention has been given to benzodiazepines and gamma-hydroxybutyric acid (GHB) related compounds owing to their alleged widespread use as date-rape drugs. Toxicologists would greatly benefit from a screening method that allows for the simultaneous detection of both groups of substances. A new capillary ... | ['Benzodiazepines', 'Beverages', 'Chromatography, Micellar Electrokinetic Capillary', 'Forensic Medicine', 'Humans', 'Hydrogen-Ion Concentration', 'Hydroxybutyrates', 'Molecular Structure', 'Sex Offenses', 'Sodium Dodecyl Sulfate', 'Surface-Active Agents'] | 15,066,708 | [['D03.633.100.079.080'], ['G07.203.100', 'J02.200'], ['E05.196.181.500'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D02.241.081.114.937', 'D02.241.511.429', 'D10.251.400.143.781'], ['G02.111.570', 'G02.466'], ['I01.198.240.748'], ['D02.033.415.220.720', 'D02.88... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
Breastfeeding knowledge and education needs of early childhood centre staff. | This survey investigated the breastfeeding knowledge, attitudes beliefs and education needs of supervisors and staff at 32 early childhood centres in New Zealand. This study explored numbers of mothers who breastfed at or supplied expressed breastmilk to the centres, and how breastfeeding education might enhance an inc... | ['Breast Feeding', 'Child Day Care Centers', 'Child, Preschool', 'Health Education', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Infant', 'Infant, Newborn', 'Needs Assessment', 'New Zealand', 'Social Support'] | 23,029,775 | [['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['J03.160', 'N02.421.143.098'], ['M01.060.406.448'], ['I02.233.332', 'N02.421.726.407'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['I02.594', '... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
BY55/CD160 cannot be considered a cytotoxic marker in cytomegalovirus-specific human CD8(+) T cells. | CD160/BY55 is a glucosyl-phosphatidylinositol (GPI)-anchored cell membrane receptor that is expressed primarily in natural killer (NK) cells. Its presence in CD8(+) T lymphocytes is considered to be a marker of cytotoxic activity, although there are few data in this regard. In the present work, we analysed the expressi... | ['Adult', 'Aged', 'Antigens, CD', 'Biomarkers', 'CD28 Antigens', 'CD57 Antigens', 'CD8-Positive T-Lymphocytes', 'Cell Differentiation', 'Cells, Cultured', 'Cytomegalovirus', 'Cytotoxicity, Immunologic', 'Follow-Up Studies', 'GPI-Linked Proteins', 'Humans', 'Kidney Transplantation', 'Membrane Glycoproteins', 'Middle Age... | 17,425,655 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.101'], ['D12.776.543.750.705.222.500', 'D23.050.301.264.894.128', 'D23.101.100.894.128'], ['D23.050.301.264.894.157', 'D23.101.100.894.157'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chemical validation and optimization of pharmacoperones targeting vasopressin type 2 receptor mutant. | A series of compounds formerly identified by high-throughput screening was studied for their ability to serve as pharmacoperones for the vasopressin type 2 receptor (V2R) mutant L83Q, which is known to cause nephrogenic diabetes insipidus (NDI). Three compounds were particularly effective in rerouting the mutant recept... | ['Amino Acid Substitution', 'Diabetes Insipidus, Nephrogenic', 'HeLa Cells', 'Humans', 'Molecular Chaperones', 'Molecular Probes', 'Mutation, Missense', 'Receptors, Vasopressin'] | 30,068,530 | [['E05.393.420.601.035', 'G05.558.109'], ['C12.777.419.135.500', 'C13.351.968.419.135.500'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.580'], ['D27.505.259.750', 'D27.720.470.530'], ['G05.365.590.650'], ['D12.776.543.750.695.910', 'D12.776.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of bradycardia in trout by centrally administered corticotropin-releasing-hormone (CRH). | The cardiovascular effects of centrally and peripherally administered synthetic salmon corticotropin-releasing-hormone (CRH), a member of a family of stress-related neuropeptides, were investigated in the unanesthetized trout, Oncorhynchus mykiss. In group 1, trout bearing a cannula in the dorsal aorta, neither intrace... | ['Animals', 'Bradycardia', 'Corticotropin-Releasing Hormone', 'Heart Rate', 'Injections, Intraventricular', 'Oncorhynchus mykiss'] | 12,915,256 | [['B01.050'], ['C14.280.067.319', 'C23.550.073.300'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E02.319.267.530.550'], ['B01.050.150.900.493.817.750.825.580.600']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychophysiological response in parachute jumps, the effect of experience and type of jump. | We aimed to analyse the effect of experience and type of parachute jump on the psychophysiological responses of jumpers. We analysed blood oxygen saturation, heart rate, blood glucose, lactate and creatinkinase, leg strength, isometric hand strength, cortical arousal, specific fine motor skills, self-confidence and cog... | ['Adult', 'Anxiety', 'Arousal', 'Aviation', 'Blood Glucose', 'Cognition', 'Creatine Kinase', 'Hand', 'Heart Rate', 'Humans', 'Lactic Acid', 'Leg', 'Military Personnel', 'Motor Skills', 'Muscle Strength', 'Oxygen', 'Practice, Psychological', 'Professional Competence', 'Psychophysiology', 'Self Concept', 'Stress, Psychol... | 28,619,292 | [['M01.060.116'], ['F01.470.132'], ['F02.830.104', 'G11.561.035'], ['J01.937.285'], ['D09.947.875.359.448.500'], ['F02.463.188'], ['D08.811.913.696.640.150'], ['A01.378.800.667'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['A01.378.610.500'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [... | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 |
Chromium diffusion and reduction in soil aggregates. | The distribution of metal contaminants such as chromium in soils can be strongly localized by transport limitations and redox gradients within soil aggregates. Measurements of Cr(VI) diffusion and reduction to Cr(III) were obtained in soil columns representing transects into soil aggregates in order to quantify influen... | ['Chromium', 'Diffusion', 'Kinetics', 'Oxidation-Reduction', 'Soil', 'Soil Pollutants'] | 11,505,996 | [['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['G01.202', 'G02.196'], ['G01.374.661', 'G02.111.490'], ['G02.700', 'G03.295.531'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bench Evaluation of Four Portable Oxygen Concentrators Under Different Conditions Representing Altitudes of 2438, 4200, and 8000 m. | Bunel, Vincent, Amr Shoukri, Frederic Choin, Serge Roblin, Cindy Smith, Thomas Similowski, Capucine Mor?lot-Panzini, and J?sus Gonzalez. Bench evaluation of four portable oxygen concentrators under different conditions representing altitudes of 2438, 4200, and 8000 m. High Alt Med Biol. 17:370-374, 2016.-Air travel is ... | ['Aircraft', 'Altitude', 'Atmospheric Pressure', 'Humans', 'Hypoxia', 'Oxygen', 'Oxygen Inhalation Therapy', 'Reproducibility of Results'] | 27,959,667 | [['J01.937.285.100'], ['G16.500.275.058', 'N06.230.058'], ['G16.500.750.274', 'N06.230.300.100.185'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['D01.268.185.550', 'D01.362.670'], ['E02.880.690'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Predictors of length of stay following shoulder arthroplasty in a high-volume UK centre. | INTRODUCTION: Shoulder arthroplasty rates are increasing in the UK. No data have been published from a UK centre on predictors of length of inpatient stay following shoulder arthroplasty. This study analyses the length of inpatient stay following shoulder arthroplasty in a high-volume UK centre and identifies predictor... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Shoulder', 'Female', 'Follow-Up Studies', 'Hospital Mortality', 'Hospitals, High-Volume', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Morbidity', 'Postoperative Complications', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Shoulder Join... | 32,302,224 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.299', 'E04.650.110.299', 'E04.680.101.110.299'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hypoglossal schwannoma-successful reinnervation and functional recovery of the tongue following tumour removal and nerve grafting. | OBJECTIVE: Hypoglossal nerve schwannomas are rare tumours that usually cause ipsilateral hypoglossal palsy. This report describes such lesions in two patients and suggests nerve grafting as part of the treatment regimen.METHOD: Two patients with intra- and extra-dural hypoglossal schwannomas respectively were treated b... | ['Carotid Artery, Internal', 'Cranial Fossa, Posterior', 'Cranial Nerve Neoplasms', 'Craniotomy', 'Female', 'Humans', 'Hypoglossal Nerve', 'Hypoglossal Nerve Diseases', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neck', 'Nerve Regeneration', 'Neurilemmoma', 'Neurosurgical Procedures', 'Occipital Bone', 'Recov... | 19,290,472 | [['A07.015.114.186.200.230'], ['A01.456.830.200', 'A02.835.232.781.750.400'], ['C04.588.614.300', 'C04.588.614.596.240', 'C10.292.225', 'C10.551.360', 'C10.551.775.250'], ['E04.525.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.120.330'], ['C10.292.525'], ['E01.370.350.825.500'], ['M01.060.116.63... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clinical and CT correlates in the diagnosis of intracranial tumours. | The correlation between clinical and CT findings in cerebral tumours was prospectively studied in 1191 consecutive referrals for cerebral CT. CT revealed a mass lesion in 51 cases (4.3%): 32 neoplasms, five haematomas and one abscess. The diagnostic specificity of CT for neoplasmic tumours was 86% (32 of 37). The clini... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Brain Damage, Chronic', 'Brain Mapping', 'Brain Neoplasms', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neurologic Examination', 'Tomography, X-Ray Computed'] | 1,895,130 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.140'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Ischemic lesion of the CNS in patients with systemic lupus erythematosus]. | UNLABELLED: In a review of 240 patients with Systemic Lupus Erythematosus we found 12 (5%) with cerebral infarctions. The average patient age was 38 years and no relation with the duration of lupus was found. The most common neurologic manifestations were hemiparesis (67%), language disturbances (25%) and ataxia (25%).... | ['Adolescent', 'Adult', 'Brain Ischemia', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Middle Aged', 'Retrospective Studies', 'Risk Factors'] | 8,048,354 | [['M01.060.057'], ['M01.060.116'], ['C10.228.140.300.150', 'C14.907.253.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Agonist interactions at the calcium pools in skinned and unskinned canine tracheal smooth muscle. | We studied the functionally discrete calcium sources used by acetylcholine, 5-hydroxytryptamine, histamine and high K+ in the dog tracheal smooth muscle. The extracellular calcium dependence of their responses was assessed by altering the calcium and by pretreatment with the calcium antagonist, nifedipine. The intracel... | ['Acetylcholine', 'Animals', 'Caffeine', 'Calcium', 'Dogs', 'Female', 'Histamine', 'In Vitro Techniques', 'Isometric Contraction', 'Kinetics', 'Male', 'Muscle Contraction', 'Muscle, Smooth', 'Nifedipine', 'Potassium Chloride', 'Serotonin', 'Theophylline', 'Trachea'] | 3,690,397 | [['D02.092.211.111'], ['B01.050'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.750.250.216.200'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['E05.481'], ['G11.427.494.472'], ['G01.374.661... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laparoscopy for differential diagnosis of a pelvic mass in a patient with Mayer-Rokitanski-K?ster-Hauser (MRKH) syndrome. | OBJECTIVE: To report a rare case of a myoma simulating a pelvic tumor in a patient with Mayer-Rokitanski-K?ster-Hauser (MRKH) syndrome. The rudimentary uterus may develop fibroids, and this event can lead to problems in differential diagnosis, especially if no vaginal reconstruction has been carried out.DESIGN: Case-re... | ['Abnormalities, Multiple', 'Adult', 'Diagnosis, Differential', 'Female', 'Gynecologic Surgical Procedures', 'Humans', 'Laparoscopy', 'Leiomyoma', 'Magnetic Resonance Imaging', 'Ovarian Neoplasms', 'Syndrome', 'Treatment Outcome', 'Ultrasonography', 'Uterine Neoplasms', 'Uterus', 'Vagina'] | 18,990,385 | [['C16.131.077'], ['M01.060.116'], ['E01.171'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C04.557.450.590.450'], ['E01.370.350.825.500'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['C23.5... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression profiling of Wnt signaling genes during gonadal differentiation and gametogenesis in rainbow trout. | Wnt signaling plays major roles in various processes, including ovarian differentiation and development in mammals. In order to explore its potential implication during gonadal development in a nonmammalian vertebrate species, expression of Wnt signaling genes was investigated in rainbow trout during gonadal differenti... | ['Animals', 'Female', 'Gametogenesis', 'In Situ Hybridization', 'Male', 'Oncorhynchus mykiss', 'Ovary', 'Real-Time Polymerase Chain Reaction', 'Sex Differentiation', 'Testis', 'Wnt Signaling Pathway'] | 22,116,193 | [['B01.050'], ['G04.152.650', 'G08.686.784.310'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['B01.050.150.900.493.817.750.825.580.600'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['E05.393.620.500.706'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of a real-time PCR to explore the intensity of Plasmodium spp. infections in native, endemic and introduced New Zealand birds. | Avian malaria, caused by Plasmodium spp., is an emerging disease in New Zealand (NZ). To detect Plasmodium spp. infection and quantify parasite load in NZ birds, a real-time polymerase chain reaction (PCR) (qPCR) protocol was used and compared with a nested PCR (nPCR) assay. A total of 202 blood samples from 14 bird sp... | ['Animals', 'Animals, Wild', 'Ducks', 'Introduced Species', 'Malaria, Avian', 'New Zealand', 'Parasitemia', 'Plasmodium', 'Prevalence', 'Real-Time Polymerase Chain Reaction', 'Songbirds'] | 28,691,648 | [['B01.050'], ['B01.050.050.300'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['C01.610.752.530.606', 'C01.920.875.606', 'C22.131.498'], ['Z01.639.760.747', 'Z01.678.100.747'], ['C01.610.695', 'C23.550.470.790.500.580'], ['B01.0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
ATP specifically bound as a hapten to a monoclonal anti-phospholipid antibody retains phosphate donor activity. | We have previously reported that each of four monoclonal antibodies to a phospholipid, phosphatidylinositol phosphate (PIP), has a phosphate binding subsite in the antigen binding site that can bind ATP (Molec. Immunol. 21, 863-868, 1984). We have now observed that antibody-bound ATP has the ability to donate a phospha... | ['Adenosine Triphosphate', 'Animals', 'Antibodies, Antiphospholipid', 'Antibodies, Monoclonal', 'Binding Sites', 'Glucose', 'Glucose-6-Phosphate', 'Glucosephosphates', 'Haptens', 'Hexokinase', 'Kinetics', 'Liposomes', 'Mice', 'Mice, Inbred BALB C', 'Phosphates', 'Phosphatidylinositols', 'Phosphorylation'] | 8,381,281 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D12.776.124.486.485.114.323.210', 'D12.776.124.790.651.114.323.210', 'D12.776.377.715.548.114.323.210'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.570.120'], ['D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Predictors of Survival in Women with High-Risk Endometrial Cancer and Comparisons of Sandwich versus Concurrent Adjuvant Chemotherapy and Radiotherapy. | Background: to elucidate the predictors of progression-free survival (PFS) and overall survival (OS) in high-risk endometrial cancer patients. Methods: the medical records of all consecutivewomen with high-risk endometrial cancer were reviewed. Results: among 92 high-risk endometrial cancer patients, 30 women experienc... | ['Aged', 'Chemotherapy, Adjuvant', 'Disease-Free Survival', 'Endometrial Neoplasms', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Proportional Hazards Models', 'Radiotherapy, Adjuvant', 'Retrospective Studies'] | 32,824,293 | [['M01.060.116.100'], ['E02.186.170', 'E02.319.170'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Declining melatonin levels and older people. How old is old? | OBJECTIVES: The purpose of this study was to investigate whether melatonin levels in older cohorts within the 'aged' population were significantly lower than in younger 'aged' individuals and hence point to a possible confound in cross-sectional studies which group individuals over 55 in one category.SETTING AND DESIGN... | ['Aged', 'Aged, 80 and over', 'Aging', 'Analysis of Variance', 'Cohort Studies', 'Humans', 'Melatonin', 'Middle Aged', 'Radioimmunoassay', 'Saliva'] | 15,665,802 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.914.481', 'D06.472.506'], ['M01.060.116.630... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
COP-BLAM regimen combined with granulocyte colony-stimulating factor and high-grade non-Hodgkin's lymphoma. | The clinical efficacy of COP-BLAM chemotherapy combined with human recombinant granulocyte colony-stimulating factor (G-CSF) was evaluated in 104 previously untreated patients with non-Hodgkin's lymphoma (NHL). According to the method of Laurence et al., a modified COP-BLAM regimen was administered every 21 days. G-CSF... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Bleomycin', 'Cyclophosphamide', 'Doxorubicin', 'Female', 'Fever', 'Granulocyte Colony-Stimulating Factor', 'Humans', 'Infections', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Neutropenia', 'P... | 7,543,059 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D09.400.420.110', 'D12.644.233.110'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
On the origin of the hierarchy of color names. | One of the fundamental problems in cognitive science is how humans categorize the visible color spectrum. The empirical evidence of the existence of universal or recurrent patterns in color naming across cultures is paralleled by the observation that color names begin to be used by individual cultures in a relatively f... | ['Cognitive Science', 'Color', 'Cross-Cultural Comparison', 'Humans', 'Language', 'Models, Psychological', 'Terminology as Topic'] | 22,509,002 | [['F04.096.628.255'], ['G01.590.540.199'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['E05.599.695'], ['L01.559.598.400']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Micro-imaging of Brain Cancer Radiation Therapy Using Phase-contrast Computed Tomography. | PURPOSE: Experimental neuroimaging provides a wide range of methods for the visualization of brain anatomic morphology down to subcellular detail. Still, each technique-specific detection mechanism presents compromises among the achievable field-of-view size, spatial resolution, and nervous tissue sensitivity, leading ... | ['Animals', 'Brain', 'Brain Neoplasms', 'Glioblastoma', 'Magnetic Resonance Imaging', 'Male', 'Microvessels', 'Neuroradiography', 'Rats', 'Rats, Inbred F344', 'X-Ray Microtomography'] | 29,976,510 | [['B01.050'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['E01.370.350.825.500'], ['A07.015.461'], ['E01.370.350.578.937', 'E01.370.350.700.560', 'E01.370.376.537.750', 'E05.629.93... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of ozonated water on the surface roughness of dental stone casts. | Infection control of dental stone cast is an important issue. Ozone is effective for disinfection against microorganisms and inactivation of viruses. However, there is little information regarding the use of ozone. We prepared 4 types of gypsum specimens and 3 types of disinfectants (4-5 ppm Ozonated water [OZW], 2% gl... | ['Calcium Sulfate', 'Dental Casting Investment', 'Dental Disinfectants', 'Dental Impression Materials', 'Glutaral', 'Materials Testing', 'Microscopy, Electron, Scanning', 'Ozone', 'Sodium Hypochlorite', 'Surface Properties', 'Water'] | 29,848,854 | [['D01.146.375', 'D01.578.215', 'D01.875.800.800.850.125'], ['D25.339.250', 'J01.637.051.339.250'], ['D27.505.954.122.425.300', 'D27.720.274.300'], ['D25.339.334', 'J01.637.051.339.334'], ['D02.047.532'], ['E05.570'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D01.362.670.600'], ['D01.210.465.800', 'D01.650.550.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A simple method for clonal selection of hepatitis A virus based on recovery of virus from radioimmunofocus overlays. | Hepatitis A virus (HAV), a non-cytopathic picornavirus, has been quantitated in cell culture by autoradiographic detection of foci of viral replication developing beneath an agarose overlay following fixation and 'staining' of the cell sheet with radiolabelled antibody (radioimmunofocus assay). Using a modification of ... | ['Animals', 'Autoradiography', 'Cell Line', 'Chlorocebus aethiops', 'DNA', 'DNA, Viral', 'Hepatovirus', 'Nucleic Acid Hybridization', 'RNA, Viral', 'Radioimmunoassay', 'Sepharose', 'Viral Plaque Assay', 'Virus Replication'] | 2,991,315 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D13.444.308'], ['D13.444.308.568'], ['B04.450.420', 'B04.820.578.750.400'], ['E05.393.661', 'G02.111.611'], ['D13.444.735.828'], ['E01.370.384.700', 'E05.478.566.639', 'E0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two distinct proton binding sites in the ATP synthase family. | The F1F0 ATP synthase utilizes energy stored in an electrochemical gradient of protons (or Na+ ions) across the membrane to synthesize ATP from ADP and phosphate. Current models predict that the protonation/deprotonation of specific acidic c ring residues is at the core of the proton translocation mechanism by this enz... | ['Adenosine Triphosphate', 'Animals', 'Bacterial Proton-Translocating ATPases', 'Binding Sites', 'Cattle', 'Cell Membrane', 'Chloroplasts', 'Dicyclohexylcarbodiimide', 'Escherichia coli', 'Fusobacteria', 'Gene Deletion', 'Halobacterium salinarum', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Mitochondria, Heart', 'Mode... | 17,910,472 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D08.811.277.040.025.325.249', 'D08.811.913.696.650.150.500.249', 'D12.776.097.130', 'D12.776.157.530.450.250.875.500.249', 'D12.776.543.585.450.250.875.500.249'], ['G02.111.570.120'], ['B01.050.150.900.649.313.500.380.271'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Somatic DNA rearrangement generates functional rat immunoglobulin kappa chain genes: the J kappa gene cluster is longer in rat than in mouse. | The kappa immunoglobulin (Ig) genes from rat kidney and from rat myeloma cells were cloned and analyzed. In kidney DNA one C kappa species is observed by Southern blotting and cloning in phage vectors; this gene most likely represents the embryonic configuration. In the IR52 myeloma DNA two C kappa species are observed... | ['Animals', 'Base Sequence', 'Cell Line', 'Cloning, Molecular', 'DNA Restriction Enzymes', 'DNA, Recombinant', 'Genes', 'Immunoglobulin J-Chains', 'Immunoglobulin Light Chains', 'Immunoglobulin kappa-Chains', 'Kidney', 'Mutation', 'Neoplasms, Experimental', 'Nucleic Acid Hybridization', 'Plasmacytoma', 'Rats'] | 6,290,320 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['E05.393.220'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.460'], ['G05.360.340.024.340'], ['D12.776.124.486.485.705.625', 'D12.776.124.790.651.705.625', 'D12.776.377.715.548.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Psychological stress and cardiovascular disease: empirical demonstration of bias in a prospective observational study of Scottish men. | OBJECTIVES: To examine the association between self perceived psychological stress and cardiovascular disease in a population where stress was not associated with social disadvantage.DESIGN: Prospective observational study with follow up of 21 years and repeat screening of half the cohort 5 years from baseline. Measure... | ['Adult', 'Age Factors', 'Angina Pectoris', 'Bias', 'Cardiovascular Diseases', 'Evidence-Based Medicine', 'Follow-Up Studies', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Odds Ratio', 'Proportional Hazards Models', 'Prospective Studies', 'Risk Factors', 'Social Class', 'Stress, Psycholog... | 12,028,978 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['N05.715.350.150', 'N06.850.490.500'], ['C14'], ['H02.249.750', 'H02.403.200.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E02.760.400', 'N0... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Influence of cation binding on the electro-optically determined electric moments of purple membranes. | Analysis of the electro-optically determined permanent dipole moment and electric polarizability of purple membrane fragments reveals the complex nature of the membrane electric moments. The problem to distinguish between the contribution of the membrane structural charges (charged groups of the polypeptide chain and p... | ['Bacteriorhodopsins', 'Cations', 'Electromagnetic Fields', 'Light', 'Membrane Potentials', 'Scattering, Radiation'] | 1,575,932 | [['D12.776.090.200', 'D12.776.157.530.450.250.875.249', 'D12.776.543.585.450.250.875.249', 'D12.776.752.812.249'], ['D01.248.497.300'], ['G01.358.500.260', 'G01.358.750.500'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E05.19... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Decreased cell proliferation and altered cytokine production in frail older adults. | BACKGROUND AND AIMS: Frailty is a geriatric syndrome that predicts increased morbidity and mortality. In order to investigate specific immune system modulations that may contribute to frailty, eleven age- and sex-matched pairs of community-dwelling frail and non-frail older adults were identified.METHODS: Peripheral bl... | ['Aged', 'Aged, 80 and over', 'Aging', 'Cell Division', 'Female', 'Frail Elderly', 'Humans', 'In Vitro Techniques', 'Interleukin-10', 'Interleukin-6', 'Leukocytes, Mononuclear', 'Lipopolysaccharides', 'Male', 'Tumor Necrosis Factor-alpha'] | 15,462,470 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['M01.060.116.100.540'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['D12.644.276.37... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Integrated platform for genome-wide screening and construction of high-density genetic interaction maps in mammalian cells. | A major challenge of the postgenomic era is to understand how human genes function together in normal and disease states. In microorganisms, high-density genetic interaction (GI) maps are a powerful tool to elucidate gene functions and pathways. We have developed an integrated methodology based on pooled shRNA screenin... | ['Animals', 'B-Lymphocytes', 'Chromosome Mapping', 'Epistasis, Genetic', 'Genome-Wide Association Study', 'Genomic Library', 'HeLa Cells', 'Humans', 'K562 Cells', 'Lymphoma', 'Mammals', 'Models, Genetic', 'Phenotype', 'RNA, Small Interfering'] | 23,739,767 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E05.393.183'], ['G05.308.207'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['G0... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Resuscitation. Nurses' skills in basic life support: a survey. | Cardiopulmonary resuscitation (CPR) skills are fundamental to the function of health professionals, but studies have shown them to be inadequate and outdated. This week, Nursing Standard launches a three-part weekly series on resuscitation. Parts two and three will address the associated ethical issues and measures of ... | ['Adult', 'Cardiopulmonary Resuscitation', 'Education, Nursing, Continuing', 'Health Knowledge, Attitudes, Practice', 'Heart Arrest', 'Humans', 'Inservice Training', 'Middle Aged', 'Nursing Staff, Hospital', 'Surveys and Questionnaires'] | 8,452,801 | [['M01.060.116'], ['E02.365.647.110'], ['I02.358.212.450', 'I02.358.462.399'], ['F01.100.150.500', 'N05.300.150.410'], ['C14.280.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['M01.060.116.630'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['E05.318.308.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Damage mechanisms in uniaxial compression of single enamel rods. | Enamel possesses a complex hierarchical structure, which bestows this tissue with unique mechanical properties. In this study, the mechanical behavior of single enamel rods was investigated under uniaxial compression. Numerical simulations were also performed using micromechanics models for individual enamel rods to id... | ['Biomechanical Phenomena', 'Compressive Strength', 'Dental Enamel', 'Elastic Modulus', 'Humans', 'Models, Biological', 'Stress, Mechanical'] | 25,460,920 | [['G01.154.090', 'G01.374.089'], ['G01.374.180'], ['A14.549.167.900.255'], ['G01.374.590.605'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['G01.374.835']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment. | In an attempt to identify the rotavirus receptor, we tested 46 cell lines of different species and tissue origins for susceptibility to infection by three N-acetyl-neuraminic (sialic) acid (SA)-dependent and five SA-independent rotavirus strains. Susceptibility to SA-dependent or SA-independent rotavirus infection vari... | ['Animals', 'Antibodies, Monoclonal', 'Antigens, CD', 'CHO Cells', 'Cells, Cultured', 'Cricetinae', 'Humans', 'Integrin alpha2', 'Integrin alpha4beta1', 'Integrin beta1', 'Integrins', 'Mice', 'Neuraminidase', 'Rats', 'Receptors, Collagen', 'Receptors, Lymphocyte Homing', 'Rotavirus', 'Sialic Acids', 'Transfection'] | 11,773,387 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.035', 'D23.101.100.110'], ['A11.251.210.200', 'A11.436.155'], ['A11.251'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.40... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DHT in prostate cancer tissue--a guide to management and therapy. | In 24 untreated stage D2 prostate cancer patients with prostate DHT levels greater than 2.5 ng/g, 20 initially responded to therapy with partial objective progression (POR) or were objectively stable (OS) for 12 or more months while four patients relapsed in less than 1 year. Of eight patients with prostate DHT levels ... | ['Castration', 'Diethylstilbestrol', 'Dihydrotestosterone', 'Humans', 'Male', 'Megestrol', 'Megestrol Acetate', 'Prognosis', 'Prostatic Neoplasms'] | 3,969,370 | [['E04.270.282', 'E04.950.165'], ['D02.455.426.559.389.150.700.725.500'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.432.531'], ['D04.210.500.745.432.531.500'], ['E01.789'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cloning and expression of Drosophila melanogaster UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I. | A TBLASTN search of the Drosophila melanogaster expressed sequence tag (EST) database with the amino acid sequence of human UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I, EC 2.4.1.101) as probe yielded a clone (GM01211) with 56% identity over 36 carboxy-terminal amino aci... | ['Amino Acid Sequence', 'Animals', 'Baculoviridae', 'Base Sequence', 'Carbohydrate Sequence', 'Cloning, Molecular', 'Drosophila melanogaster', 'Insect Proteins', 'Molecular Sequence Data', 'N-Acetylglucosaminyltransferases', 'Sequence Homology, Amino Acid'] | 11,308,019 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B04.280.065', 'B04.525.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.160', 'L01.453.245.667.160'], ['E05.393.220'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D12.776.093.500'], ['L01.453.245.667'], ['D08.811.913.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Free-flow electrophoretic analysis of endosome subpopulations of rat hepatocytes. | The separation of functional early and late endosomes from other cellular compartments by free-flow electrophoresis (FFE) has been previously demonstrated in nonpolarized cells. Here, using 125I-labeled anti-secretory component antibodies ([125I]SC Ab) and FITC-labeled asialoorosomucoid (FITC-ASOR) as markers of the tr... | ['Animals', 'Antibodies', 'Asialoglycoproteins', 'Cell Membrane', 'Cold Temperature', 'Electrophoresis', 'Endocytosis', 'Endosomes', 'Fluorescein-5-isothiocyanate', 'Fluorescent Dyes', 'Iodine Radioisotopes', 'Liver', 'Lysosomes', 'Male', 'Orosomucoid', 'Perfusion', 'Rats', 'Secretory Component', 'Temperature'] | 9,527,479 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.395.140'], ['A11.284.149'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E05.196.401', 'E05.301.300'], ['G04.417'], ['A... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Conceptualizing disability in US national surveys: application of the World Health Organization's (WHO) International Classification of Functioning, Disability, and Health (ICF) framework. | PURPOSE: Disability data inform resource allocation and utilization, characterize functioning and changes over time, and provide a mechanism to monitor progress toward promoting and protecting the rights of individuals with disability. Data collection efforts, however, define and measure disability in varied ways. Our ... | ['Child', 'Concept Formation', 'Data Collection', 'Disability Evaluation', 'Disabled Persons', 'Humans', 'International Classification of Functioning, Disability and Health', 'Quality of Life', 'World Health Organization'] | 24,948,041 | [['M01.060.406'], ['F02.463.785.233'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E01.370.400'], ['M01.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.945.450'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['N03.540.514.718.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Synthesis of substituted stilbenes via the Knoevenagel condensation. | Knoevenagel condensations between aldehydes and substrates containing active methylene groups were carried out in ethanol at room temperature, in the presence of potassium phosphate, to afford unsymmetrical olefins. These condensations have been shown to afford only the E-isomers in greater than 80% yields. Salicylalde... | ['Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Models, Chemical', 'Spectrophotometry, Infrared', 'Spectrophotometry, Ultraviolet', 'Stilbenes'] | 18,007,467 | [['E05.196.867.519'], ['E05.196.566'], ['E05.599.495'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D02.455.426.559.389.150.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Primary stent angioplasty of the inferior vena cava after liver transplantation and liver resection. | PURPOSE: This study evaluated technical efficacy and safety of stent angioplasty of the inferior vena cava (IVC) after liver transplantation or liver resection and analysis of changes in creatinine levels and patients' weight.METHODS: Between October 2004 and February 2011, 16 patients (mean age, 52.6 years) with sympt... | ['Adolescent', 'Adult', 'Aged', 'Angioplasty', 'Body Weight', 'Child', 'Constriction, Pathologic', 'Creatinine', 'Diagnostic Imaging', 'Female', 'Hepatectomy', 'Humans', 'Liver Diseases', 'Liver Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Stents', 'Treatment Outcome... | 24,091,757 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.148.050', 'E04.100.814.529.124', 'E04.502.382.124', 'E05.157.016'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['C23.300.287'], ['D03.383.129.308.207'], ['E01.370.350'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A further family with congenital renal proximal tubular dysgenesis. | A new syndrome of oligohydramnios, Potter's syndrome, and anuric renal failure leading to stillbirth or neonatal death from respiratory failure has recently been described. Histologically, there is renal tubular dysgenesis, especially of the proximal tubules, and apparent glomerular crowding. To date, five families hav... | ['Adult', 'Anuria', 'Consanguinity', 'Female', 'Fetal Death', 'Genes, Recessive', 'Humans', 'Kidney Tubules, Proximal', 'Male', 'Pedigree', 'Pregnancy', 'Syndrome'] | 2,359,105 | [['M01.060.116'], ['C12.777.419.078', 'C12.777.934.141', 'C13.351.968.419.078', 'C13.351.968.934.070'], ['G05.090.403.180', 'G05.180'], ['C13.703.223', 'C23.550.260.585'], ['G05.360.340.024.340.415', 'G05.420.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453.736.560.570'], ['E05.393.673'], ['G08.686... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Repair of spondylolytic defect with a cable screw reconstruction. | We present the clinical and radiological results of surgical repair for refractory spondylolysis in 20 patients at a minimum follow-up of 2 years. Seventeen of them were reassessed after 5 years. The Oswestry scores revealed good to excellent results in 90% (18/20 patients), indicating a good outcome with surgical repa... | ['Adolescent', 'Adult', 'Biomechanical Phenomena', 'Bone Screws', 'Bone Wires', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Spinal Fusion', 'Spondylolysis', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 17,431,623 | [['M01.060.057'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.15... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Force transmission through the distal ulna: effect of ulnar variance, lunate fossa angulation, and radial and palmar tilt of the distal radius. | The relationship between the amount of force transmitted through the distal ulna and seven radiologically apparent anatomic parameters (ulnar variance, radial tilt, palmar tilt, lunate fossa angulation, carpal height, carpal ulnar distance, and ulnar head inclination) was examined in 58 fresh cadaver forearms. A positi... | ['Analysis of Variance', 'Cadaver', 'Carpal Bones', 'Humans', 'Radius', 'Range of Motion, Articular', 'Regression Analysis', 'Ulna', 'Wrist Joint'] | 1,613,214 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C23.550.260.224'], ['A02.835.232.087.319.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.090.700'], ['E01.370.600.700', 'G11.427.760'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['A02.835.232.087.090... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
What do all personality disorders have in common? Ineffectiveness and uncooperativeness. | We still lack operative and theoretically founded definitions of what a personality disorder (PD) is, as well as empirically validated and feasible instruments to measure the disorder construct. The Temperament and Character Inventory (TCI) is the only personality instrument that explicitly distinguishes personality st... | ['Adolescent', 'Adult', 'Aged', 'Case-Control Studies', 'Character', 'Comorbidity', 'Cooperative Behavior', 'Diagnostic and Statistical Manual of Mental Disorders', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Models, Psychological', 'Personality Disorders', 'Personality Inventory', 'Self Concept', '... | 18,970,905 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F01.752.190'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.813.115'], ['L01.453.245.945.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Effects of low lead exposure on neuro-behavioral function in the rat. | Small doses (45-180 micrograms/g) of lead acetate were administered to male rats by gavage every day during the first 3 wk of life. A blood concentration of approximately 59 micrograms/100 ml blood produced signs of disturbances in reflex development and some changes in emotional behavior. Larger doses resulted in subt... | ['Animals', 'Behavior', 'Blinking', 'Conditioning, Operant', 'Dose-Response Relationship, Drug', 'Lead', 'Male', 'Motor Activity', 'Rats', 'Rats, Inbred Strains', 'Reflex'] | 6,830,315 | [['B01.050'], ['F01.145'], ['G11.561.731.127', 'G14.152'], ['F02.463.425.179.509'], ['G07.690.773.875', 'G07.690.936.500'], ['D01.268.556.435', 'D01.552.544.435'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'],... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infected mucous cyst of the finger. | The potentially serious complication of septic arthritis of the distal interphalangeal joint of the finger secondary to an infected mucous cyst is documented with a report of four cases seen within the past 6 years. Debridement, open packing, and antibiotic therapy resulted in satisfactory control of the infection in t... | ['Aged', 'Anti-Bacterial Agents', 'Arthritis, Infectious', 'Debridement', 'Female', 'Finger Joint', 'Humans', 'Mucocele'] | 6,715,835 | [['M01.060.116.100'], ['D27.505.954.122.085'], ['C01.100', 'C05.550.114.099'], ['E04.176'], ['A02.835.583.405.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.182.511']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pilot study of the use of the ECFMG clinical competence assessment to provide profiles of clinical competencies of graduates of foreign medical schools for residency directors. Educational Commission for Foreign Medical Graduates. | PURPOSE: To conduct the first of a series of pilot projects of the clinical competence assessment (CCA) of the Educational Commission for Foreign Medical Graduates (ECFMG) in order to provide profiles of clinical competencies of graduates of foreign medical schools for residency directors in the United States and for g... | ['Clinical Competence', 'Educational Measurement', 'Foreign Medical Graduates', 'Humans', 'Internship and Residency', 'Physician Executives', 'Pilot Projects'] | 8,286,005 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.399'], ['M01.526.407.435', 'M01.526.485.810.390', 'N02.360.810.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['M01.526.070.700', 'M01.526.485.800', 'N02.360.800'], ['E05.318.372.750', 'E05.337.737', 'N05.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Enantiomeric resolution of the calcium channel antagonist 8-benzylamino-8,11-oxapentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]unde cane (NGP 1-01). | We report the enantiomeric resolution and results of studies designed to probe possible enantiospecific calcium channel activity of 8-benzylamino-8,11-oxapentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undec ane (NGP 1-01), a known polycyclic benzylamino calcium channel antagonist. R-(-)-acetylmandeloylchloride was used to gene... | ['Animals', 'Bridged-Ring Compounds', 'Calcium Channel Blockers', 'Chromatography, High Pressure Liquid', 'Electrophysiology', 'Guinea Pigs', 'Heart', 'In Vitro Techniques', 'Myocardium', 'Patch-Clamp Techniques', 'Stereoisomerism'] | 9,879,570 | [['B01.050'], ['D02.455.426.100', 'D04.075'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['E05.196.181.400.300'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.992.550'], ['A07.541'], ['E05.481'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['E05.200.500.905', 'E05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[The role of frequency doubling perimetry in the diagnosis of glaucoma: screening in employees of a public hospital in an urban area of S?o Paulo]. | PURPOSE: To study the prevalence of glaucoma in employees of a public hospital in S?o Paulo and to analyze the role of frequency doubling perimetry along with non-contact tonometry and direct ophthalmoscopy, in the screening for glaucoma.METHODS: 612 employees of the Central Hospital of the "Santa Casa de S?o Paulo" we... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brazil', 'Female', 'Glaucoma', 'Hospitals, Public', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Ophthalmoscopy', 'Personnel, Hospital', 'Prevalence', 'Sensitivity and Specificity', 'Tonometry, Ocular', 'Urban Population', 'Visual Field Tests'] | 15,824,803 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.757.176'], ['C11.525.381'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Resolution of blur in the older eye: neural compensation in addition to optics? | This study examined the roles of pupillary miosis and experience-mediated compensation in older observers' superior ability to read optically blurred text. The size thresholds of younger and older adult observers for reading common words and identifying line drawings of everyday objects were compared with natural and a... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Aging', 'Female', 'Form Perception', 'Humans', 'Lighting', 'Male', 'Middle Aged', 'Reading', 'Sensory Thresholds', 'Time Factors', 'Vision Tests', 'Visual Acuity', 'Young Adult'] | 20,616,120 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['F02.463.593.373', 'F02.463.593.778.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.230.150.410'], ['M01.060.116.630'], ['L01.559.423.557'], ['F02.463.593.710'], ['G01.910.857'], ['E01... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Identification of paxillin domains interacting with â-catenin. | Barrier-protective agonists induce association of focal adhesions (FA) and adherens junctions (AJ) in endothelial cells. Here we identified specific domains of FA protein paxillin interacting with AJ protein and examined regulation of paxillin domain interactions with â-catenin by Rac GTPase. Co-expression of paxillin ... | ['Adherens Junctions', 'Allosteric Site', 'Endothelial Cells', 'Escherichia coli', 'Focal Adhesions', 'Gene Expression Regulation', 'Glutathione Transferase', 'HEK293 Cells', 'Humans', 'Paxillin', 'Plasmids', 'Protein Binding', 'Protein Structure, Tertiary', 'Proto-Oncogene Proteins c-akt', 'Recombinant Proteins', 'Sig... | 22,728,435 | [['A11.284.149.165.420.020'], ['G02.111.570.120.147'], ['A11.436.275'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.284.149.165.165.285'], ['G05.308'], ['D08.811.913.225.500'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360.024.316', 'D12.776.157... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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