id stringlengths 1 7 | question_id stringlengths 1 7 | document_id stringlengths 1 7 | question stringlengths 12 382 | type stringclasses 1
value | choices list | context stringlengths 423 3.87k | answer sequence |
|---|---|---|---|---|---|---|---|
0 | 1 | 2 | Attributes of brain metastases from XXXX .
| multiple_choice | [
"@entity1",
"@entity0",
"@entity5",
"@entity4",
"@entity2",
"@entity3"
] | BACKGROUND: Most brain metastases arise from @entity0 . Few studies compare the brain regions they involve, their numbers and intrinsic attributes. METHODS: Records of all @entity1 referred to Radiation Oncology for treatment of symptomatic brain metastases were obtained. Computed tomography (n = 56) or magnetic resona... | [
"@entity0"
] |
3 | 4 | 5 | Changes of serum XXXX concentration after intravitreal injection of Avastin in treatment of @entity6 .
| multiple_choice | [
"@entity1",
"@entity8",
"@entity6",
"@entity7",
"@entity4"
] | PURPOSE: Avastin (bevacizumab) intravitreal injections are widely used for treatment of @entity6 . The aim of our study was to analyze effect of 1.25 mg of intravitreal Avastin on serum concentration of @entity7 ( @entity7 ) in @entity6 @entity1 . METHODS: @entity1 were 10 @entity6 @entity1 on insulin therapy, without ... | [
"@entity7"
] |
6 | 7 | 8 | Changes of serum @entity7 concentration after intravitreal injection of Avastin in treatment of XXXX .
| multiple_choice | [
"@entity1",
"@entity8",
"@entity6",
"@entity7",
"@entity4"
] | PURPOSE: Avastin (bevacizumab) intravitreal injections are widely used for treatment of @entity6 . The aim of our study was to analyze effect of 1.25 mg of intravitreal Avastin on serum concentration of @entity7 ( @entity7 ) in @entity6 @entity1 . METHODS: @entity1 were 10 @entity6 @entity1 on insulin therapy, without ... | [
"@entity6"
] |
9 | 10 | 11 | Sonographic evaluation of the greater occipital nerve in XXXX .
| multiple_choice | [
"@entity1",
"@entity10",
"@entity9"
] | OBJECTIVES: @entity9 is a @entity10 that may result from greater occipital nerve entrapment. Entrapped peripheral nerves typically have an increase in cross-sectional area. The purpose of this study was to measure the cross-sectional area and circumference of symptomatic and asymptomatic greater occipital nerves in @en... | [
"@entity9"
] |
12 | 13 | 14 | Expression levels of Fas/ @entity12 mRNA in @entity1 XXXX stem cells.
| multiple_choice | [
"@entity11",
"@entity1",
"@entity12",
"@entity13"
] | Despite advancements in research made over the past decades, the prognosis of @entity11 remains dismal. Fas/ @entity12 ( @entity12 )-related immunotherapy may be regarded as a treatment of choice as it can induce the apoptosis of @entity11 cells, and has shown promising results in experimental studies. Over the years, ... | [
"@entity13"
] |
15 | 16 | 17 | Expression levels of Fas/ XXXX mRNA in @entity1 @entity13 stem cells.
| multiple_choice | [
"@entity11",
"@entity1",
"@entity12",
"@entity13"
] | Despite advancements in research made over the past decades, the prognosis of @entity11 remains dismal. Fas/ @entity12 ( @entity12 )-related immunotherapy may be regarded as a treatment of choice as it can induce the apoptosis of @entity11 cells, and has shown promising results in experimental studies. Over the years, ... | [
"@entity12"
] |
18 | 19 | 20 | Expression levels of Fas/ @entity12 mRNA in XXXX @entity13 stem cells.
| multiple_choice | [
"@entity11",
"@entity1",
"@entity12",
"@entity13"
] | Despite advancements in research made over the past decades, the prognosis of @entity11 remains dismal. Fas/ @entity12 ( @entity12 )-related immunotherapy may be regarded as a treatment of choice as it can induce the apoptosis of @entity11 cells, and has shown promising results in experimental studies. Over the years, ... | [
"@entity1"
] |
21 | 22 | 23 | Does a standard measure of self-reported physical disability correlate with clinician perception of impairment related to XXXX screening?
| multiple_choice | [
"@entity5",
"@entity1",
"@entity0",
"@entity14"
] | BACKGROUND: Adults with physical disabilities are less likely than others to receive @entity5 screening. It is not known, however, whether commonly used measures assess elements of physical ability necessary for successful screening. The objective of this exploratory study was to determine whether @entity1 who reported... | [
"@entity5"
] |
24 | 25 | 26 | Chronic toxic demyelination in the central nervous system leads to XXXX despite remyelination.
| multiple_choice | [
"@entity17",
"@entity20",
"@entity19",
"@entity16",
"@entity18",
"@entity21",
"@entity15"
] | The majority of @entity15 fail to remyelinate after chronic demyelinating episodes resulting in @entity16 . In the current study, chronic @entity17 was investigated by using the @entity18 model, a toxic @entity17 model. C57BL/6 @entity19 were administered a 0.2% @entity18 diet up to 16 weeks to induce chronic @entity17... | [
"@entity21"
] |
27 | 28 | 29 | A randomized controlled trial of intensive sleep retraining (ISR): a brief conditioning treatment for XXXX .
| multiple_choice | [
"@entity1",
"@entity23",
"@entity24",
"@entity25",
"@entity22"
] | STUDY OBJECTIVE: To investigate the effectiveness of intensive sleep retraining in comparison and combination with traditional behavioral intervention for chronic @entity22 . @entity1 : Seventy-nine volunteers with @entity22 (with or without sleep maintenance difficulties) were randomly assigned either to intensive sle... | [
"@entity22"
] |
30 | 31 | 32 | Interrelationships between body mass, XXXX desaturation, and @entity27 indices in a sleep clinic population.
| multiple_choice | [
"@entity1",
"@entity28",
"@entity26",
"@entity27",
"@entity25"
] | STUDY OBJECTIVES: To investigate the relationship between @entity26 desaturation index (ODI), body mass index (BMI), and @entity27 index (AHI) in a large sleep clinic population. DESIGN: Retrospective observational. SETTING: @entity25 clinic. @entity1 OR @entity1 : 11,448 individuals undergoing diagnostic polysomnograp... | [
"@entity26"
] |
33 | 34 | 35 | Interrelationships between body mass, @entity26 desaturation, and XXXX indices in a sleep clinic population.
| multiple_choice | [
"@entity1",
"@entity28",
"@entity26",
"@entity27",
"@entity25"
] | STUDY OBJECTIVES: To investigate the relationship between @entity26 desaturation index (ODI), body mass index (BMI), and @entity27 index (AHI) in a large sleep clinic population. DESIGN: Retrospective observational. SETTING: @entity25 clinic. @entity1 OR @entity1 : 11,448 individuals undergoing diagnostic polysomnograp... | [
"@entity27"
] |
36 | 37 | 38 | Infliximab in pediatric XXXX rapidly decreases fecal calprotectin levels.
| multiple_choice | [
"@entity1",
"@entity32",
"@entity31",
"@entity33",
"@entity29",
"@entity30"
] | AIM: To study the response to infliximab in pediatric @entity29 ( @entity29 ), as reflected in fecal calprotectin levels. METHODS: Thirty-six pediatric @entity1 with @entity29 [23 @entity30 ( @entity30 ), 13 @entity31 ( @entity31 ); median age 14 years] were treated with infliximab. Fecal calprotectin was measured at b... | [
"@entity29"
] |
39 | 40 | 41 | Photodynamic therapy of C6-implanted @entity11 cells in the @entity35 brain employing second-generation photosensitizer XXXX .
| multiple_choice | [
"@entity41",
"@entity39",
"@entity5",
"@entity4",
"@entity36",
"@entity11",
"@entity40",
"@entity35",
"@entity37",
"@entity38",
"@entity34"
] | OBJECT: The usefulness of @entity34 ( @entity34 ) as a local therapy for @entity11 was evaluated by investigating histological changes in a @entity35 @entity36 model treated with a combination of @entity37 , a water-soluble photosensitizer derived from @entity38 and exposure to a diode laser. METHODS: @entity11 cells (... | [
"@entity37"
] |
42 | 43 | 44 | Photodynamic therapy of C6-implanted XXXX cells in the @entity35 brain employing second-generation photosensitizer @entity37 .
| multiple_choice | [
"@entity41",
"@entity39",
"@entity5",
"@entity4",
"@entity36",
"@entity11",
"@entity40",
"@entity35",
"@entity37",
"@entity38",
"@entity34"
] | OBJECT: The usefulness of @entity34 ( @entity34 ) as a local therapy for @entity11 was evaluated by investigating histological changes in a @entity35 @entity36 model treated with a combination of @entity37 , a water-soluble photosensitizer derived from @entity38 and exposure to a diode laser. METHODS: @entity11 cells (... | [
"@entity11"
] |
45 | 46 | 47 | Photodynamic therapy of C6-implanted @entity11 cells in the XXXX brain employing second-generation photosensitizer @entity37 .
| multiple_choice | [
"@entity41",
"@entity39",
"@entity5",
"@entity4",
"@entity36",
"@entity11",
"@entity40",
"@entity35",
"@entity37",
"@entity38",
"@entity34"
] | OBJECT: The usefulness of @entity34 ( @entity34 ) as a local therapy for @entity11 was evaluated by investigating histological changes in a @entity35 @entity36 model treated with a combination of @entity37 , a water-soluble photosensitizer derived from @entity38 and exposure to a diode laser. METHODS: @entity11 cells (... | [
"@entity35"
] |
48 | 49 | 50 | Diagnosis of the most frequent benign XXXX : is ultrasonography accurate and reproducible?
| multiple_choice | [
"@entity43",
"@entity1",
"@entity48",
"@entity42",
"@entity46",
"@entity45",
"@entity47",
"@entity44"
] | OBJECTIVE: To evaluate the reproducibility and the accuracy of B-mode ultrasonographic features of three different kinds of benign @entity42 : @entity43 , @entity44 , and @entity45 . METHODS: Digitally stored B-mode sonographic images of 98 @entity1 submitted to surgery for the presence of an adnexal mass were evaluate... | [
"@entity42"
] |
51 | 52 | 53 | Local thrombolysis for severe XXXX .
| multiple_choice | [
"@entity1",
"@entity51",
"@entity50",
"@entity49"
] | BACKGROUND AND PURPOSE: @entity49 is a rare entity that can be difficult to manage. Most @entity1 with @entity50 recover after treatment with heparin, but a subgroup of severe @entity50 has a poor prognosis. Those @entity1 may benefit from intrasinus thrombolysis. The purpose of this research was to carry out a retrosp... | [
"@entity50"
] |
54 | 55 | 56 | XXXX : steps to maximize success and minimize effect for assisted reproductive outcome.
| multiple_choice | [
"@entity43",
"@entity1",
"@entity52",
"@entity53"
] | OBJECTIVE: To investigate the strategies used to decrease the risk of @entity43 ( @entity43 ) and their impact on pregnancy and live birth rates. DESIGN: Retrospective cohort analysis. SETTING: University hospital. @entity1 (S): One hundred eighty-eight @entity1 undergoing fresh @entity52 ( @entity52 ) cycles between 2... | [
"@entity43"
] |
57 | 58 | 59 | Immune responses to XXXX antigen in @entity58 -/- @entity19 and the effect of eosinophil ablation.
| multiple_choice | [
"@entity1",
"@entity57",
"@entity59",
"@entity55",
"@entity19",
"@entity60",
"@entity61",
"@entity54",
"@entity56",
"@entity58"
] | BACKGROUND: Exposure to @entity54 allergens results in enhanced total serum IgE and peripheral blood eosinophils in @entity19 . The associated @entity55 and immunologic responses are comparable to those detected in @entity1 @entity56 @entity57 . Allergen-induced cytokines are thought to regulate the inflammatory and im... | [
"@entity54"
] |
60 | 61 | 62 | Immune responses to @entity54 antigen in XXXX -/- @entity19 and the effect of eosinophil ablation.
| multiple_choice | [
"@entity1",
"@entity57",
"@entity59",
"@entity55",
"@entity19",
"@entity60",
"@entity61",
"@entity54",
"@entity56",
"@entity58"
] | BACKGROUND: Exposure to @entity54 allergens results in enhanced total serum IgE and peripheral blood eosinophils in @entity19 . The associated @entity55 and immunologic responses are comparable to those detected in @entity1 @entity56 @entity57 . Allergen-induced cytokines are thought to regulate the inflammatory and im... | [
"@entity58"
] |
63 | 64 | 65 | Immune responses to @entity54 antigen in @entity58 -/- XXXX and the effect of eosinophil ablation.
| multiple_choice | [
"@entity1",
"@entity57",
"@entity59",
"@entity55",
"@entity19",
"@entity60",
"@entity61",
"@entity54",
"@entity56",
"@entity58"
] | BACKGROUND: Exposure to @entity54 allergens results in enhanced total serum IgE and peripheral blood eosinophils in @entity19 . The associated @entity55 and immunologic responses are comparable to those detected in @entity1 @entity56 @entity57 . Allergen-induced cytokines are thought to regulate the inflammatory and im... | [
"@entity19"
] |
66 | 67 | 68 | Clinical correlates of XXXX in cognitively normal older adults.
| multiple_choice | [
"@entity64",
"@entity66",
"@entity63",
"@entity62",
"@entity65"
] | Many research studies have demonstrated asymptomatic @entity62 ( @entity62 ) in older adults, which are postulated to be @entity63 in origin. We hypothesized that certain clinical predictors, measured in a population of healthy older adults, would have a positive relationship with WMH scoring on magnetic resonance imag... | [
"@entity62"
] |
69 | 70 | 71 | Left atrial volume is an independent predictor of exercise capacity in XXXX with isolated left ventricular diastolic dysfunction.
| multiple_choice | [
"@entity1",
"@entity67"
] | Left atrial (LA) volume reflects left ventricular (LV) diastolic properties. The latter is an important determinant of exercise capacity in @entity1 with normal LV systolic function. We hypothesized that LA volume predicts exercise capacity in @entity1 with isolated LV @entity67 . Echocardiography and treadmill exercis... | [
"@entity1"
] |
72 | 73 | 74 | @entity69 in korean @entity1 with XXXX .
| multiple_choice | [
"@entity1",
"@entity71",
"@entity69",
"@entity70",
"@entity68"
] | OBJECTIVE: The aim of the present study was to investigate the relationship between @entity68 , ferritin, @entity69 , total @entity68 binding capacity (TIBC), hemoglobin, mean corpuscular volume (MCV) @entity70 ( @entity70 ), and @entity70 ( @entity70 ) in @entity1 with @entity71 . METHODS: MethodsaaThe sample consiste... | [
"@entity71"
] |
75 | 76 | 77 | XXXX in korean @entity1 with @entity71 .
| multiple_choice | [
"@entity1",
"@entity71",
"@entity69",
"@entity70",
"@entity68"
] | OBJECTIVE: The aim of the present study was to investigate the relationship between @entity68 , ferritin, @entity69 , total @entity68 binding capacity (TIBC), hemoglobin, mean corpuscular volume (MCV) @entity70 ( @entity70 ), and @entity70 ( @entity70 ) in @entity1 with @entity71 . METHODS: MethodsaaThe sample consiste... | [
"@entity69"
] |
78 | 79 | 80 | @entity69 in korean XXXX with @entity71 .
| multiple_choice | [
"@entity1",
"@entity71",
"@entity69",
"@entity70",
"@entity68"
] | OBJECTIVE: The aim of the present study was to investigate the relationship between @entity68 , ferritin, @entity69 , total @entity68 binding capacity (TIBC), hemoglobin, mean corpuscular volume (MCV) @entity70 ( @entity70 ), and @entity70 ( @entity70 ) in @entity1 with @entity71 . METHODS: MethodsaaThe sample consiste... | [
"@entity1"
] |
81 | 82 | 83 | Disorder-specific functional abnormalities during sustained attention in youth with @entity71 ( XXXX ) and with autism.
| multiple_choice | [
"@entity1",
"@entity75",
"@entity73",
"@entity71",
"@entity51",
"@entity72",
"@entity74",
"@entity76"
] | @entity71 ( @entity71 ) and @entity72 ( @entity72 ) are often comorbid and share @entity73 in sustained attention. A key question is whether this shared cognitive phenotype is based on common or different underlying pathophysiologies. To elucidate this question, we compared 20 @entity1 with @entity71 to 20 age and IQ m... | [
"@entity71"
] |
84 | 85 | 86 | Disorder-specific functional abnormalities during sustained attention in youth with XXXX ( @entity71 ) and with autism.
| multiple_choice | [
"@entity1",
"@entity75",
"@entity73",
"@entity71",
"@entity51",
"@entity72",
"@entity74",
"@entity76"
] | @entity71 ( @entity71 ) and @entity72 ( @entity72 ) are often comorbid and share @entity73 in sustained attention. A key question is whether this shared cognitive phenotype is based on common or different underlying pathophysiologies. To elucidate this question, we compared 20 @entity1 with @entity71 to 20 age and IQ m... | [
"@entity71"
] |
87 | 88 | 89 | Function after injection of XXXX with a bioceramic.
| multiple_choice | [
"@entity1",
"@entity82",
"@entity83",
"@entity78",
"@entity79",
"@entity80",
"@entity86",
"@entity84",
"@entity77",
"@entity85",
"@entity81"
] | BACKGROUND: A novel @entity77 - @entity78 composite injectable bone graft substitute has been approved by the FDA for filling @entity79 in a nonweightbearing application based on preclinical studies. Its utility has not been documented in the literature. QUESTIONS/PURPOSES: We therefore determined postoperative functio... | [
"@entity79"
] |
90 | 91 | 92 | The face of XXXX : a subjective and objective study.
| multiple_choice | [
"@entity1",
"@entity90",
"@entity87",
"@entity89",
"@entity92",
"@entity88",
"@entity91"
] | We report a study of 55 subjects with @entity87 , aged 9 months to 35 years. Each @entity1 has been evaluated with an assessment of "gestalt" and detailed facial measurement, using previously published methodology, with compilation of Z score pattern profiles. The facial phenotype of @entity87 is quite distinctive, eve... | [
"@entity87"
] |
93 | 94 | 95 | Quantification of angiogenesis by CT perfusion imaging in @entity96 of XXXX .
| multiple_choice | [
"@entity97",
"@entity96",
"@entity5",
"@entity93",
"@entity95",
"@entity100",
"@entity98",
"@entity94",
"@entity99"
] | BACKGROUND: @entity5 angiogenesis is essential for primary and metastatic @entity5 growth. Computed tomography perfusion ( @entity93 ) is a new imaging method, made possible by the recent development of fast CT scanners and improved data analysis techniques, which allows measurement of the physiologic and hemodynamic p... | [
"@entity95"
] |
96 | 97 | 98 | Quantification of angiogenesis by CT perfusion imaging in XXXX of @entity95 .
| multiple_choice | [
"@entity97",
"@entity96",
"@entity5",
"@entity93",
"@entity95",
"@entity100",
"@entity98",
"@entity94",
"@entity99"
] | BACKGROUND: @entity5 angiogenesis is essential for primary and metastatic @entity5 growth. Computed tomography perfusion ( @entity93 ) is a new imaging method, made possible by the recent development of fast CT scanners and improved data analysis techniques, which allows measurement of the physiologic and hemodynamic p... | [
"@entity96"
] |
99 | 100 | 101 | The assessment of adherence of XXXX individuals to treatment and lifestyle change recommendations.
| multiple_choice | [
"@entity1",
"@entity101",
"@entity102"
] | OBJECTIVE: Most of studies about adherence in @entity101 highlight the adherence to the medical treatment but do not include the adherence to the other recommendations, such as lifestyle modifications. The factors effective on adherence to each type of recommendation may differ. Accordingly, we aimed in this study to s... | [
"@entity101"
] |
102 | 103 | 104 | Antitumour promoting activity of @entity103 in @entity19 XXXX .
| multiple_choice | [
"@entity5",
"@entity19",
"@entity103",
"@entity106",
"@entity105",
"@entity104"
] | There has been growing interest in recent years in the potential of brassica vegetables (cabbage, cauliflower, brussels sprouts, etc.) as vectors for the introduction of anticarcinogenic compounds in the diet. @entity103 , a major @entity104 metabolite present in the cruciferous vegetables, has been found to inhibit va... | [
"@entity105"
] |
105 | 106 | 107 | Antitumour promoting activity of XXXX in @entity19 @entity105 .
| multiple_choice | [
"@entity5",
"@entity19",
"@entity103",
"@entity106",
"@entity105",
"@entity104"
] | There has been growing interest in recent years in the potential of brassica vegetables (cabbage, cauliflower, brussels sprouts, etc.) as vectors for the introduction of anticarcinogenic compounds in the diet. @entity103 , a major @entity104 metabolite present in the cruciferous vegetables, has been found to inhibit va... | [
"@entity103"
] |
108 | 109 | 110 | Antitumour promoting activity of @entity103 in XXXX @entity105 .
| multiple_choice | [
"@entity5",
"@entity19",
"@entity103",
"@entity106",
"@entity105",
"@entity104"
] | There has been growing interest in recent years in the potential of brassica vegetables (cabbage, cauliflower, brussels sprouts, etc.) as vectors for the introduction of anticarcinogenic compounds in the diet. @entity103 , a major @entity104 metabolite present in the cruciferous vegetables, has been found to inhibit va... | [
"@entity19"
] |
111 | 112 | 113 | XXXX -induced cytoplasmic accumulation of beta1-integrin in @entity35 liver enzyme altered foci; an immunohistological study.
| multiple_choice | [
"@entity35",
"@entity107",
"@entity108",
"@entity109"
] | In this immunohistological study we investigated integrin expression in EAF in female @entity35 treated with @entity107 ( @entity108 ) as initiator and @entity109 (PB) as promotor ( @entity108 -PB treatment) for up to 32 weeks. Using a beta1-integrin antibody, there was an increased cytoplasmic staining and a decreased... | [
"@entity109"
] |
114 | 115 | 116 | @entity109 -induced cytoplasmic accumulation of beta1-integrin in XXXX liver enzyme altered foci; an immunohistological study.
| multiple_choice | [
"@entity35",
"@entity107",
"@entity108",
"@entity109"
] | In this immunohistological study we investigated integrin expression in EAF in female @entity35 treated with @entity107 ( @entity108 ) as initiator and @entity109 (PB) as promotor ( @entity108 -PB treatment) for up to 32 weeks. Using a beta1-integrin antibody, there was an increased cytoplasmic staining and a decreased... | [
"@entity35"
] |
117 | 118 | 119 | [Round Table: Immunological XXXX mediated by IgE].
| multiple_choice | [
"@entity1",
"@entity115",
"@entity4",
"@entity114",
"@entity117",
"@entity111",
"@entity113",
"@entity112",
"@entity116",
"@entity110"
] | @entity110 is characterized by the appearance of hives and @entity111 . Those hives are formed by @entity4 and vasodilatation and they disappear when they are pressed on. The acute presentation is extremely common and affects between 10 and 20% of the population at a determined moment. In its simplest form, @entity110 ... | [
"@entity110"
] |
120 | 121 | 122 | Incidence of XXXX in adults with @entity119 .
| multiple_choice | [
"@entity1",
"@entity118",
"@entity120",
"@entity119"
] | OBJECTIVE: To examine the incidence of raised pulmonary artery pressure and resistance in adults with isolated @entity118 (so called secundum defect) or @entity119 . DESIGN: A historical, retrospective, unrandomised study. SETTING: A tertiary referral centre. METHODS: Cardiac catheterisation was performed in all @entit... | [
"@entity120"
] |
123 | 124 | 125 | Incidence of @entity120 in adults with XXXX .
| multiple_choice | [
"@entity1",
"@entity118",
"@entity120",
"@entity119"
] | OBJECTIVE: To examine the incidence of raised pulmonary artery pressure and resistance in adults with isolated @entity118 (so called secundum defect) or @entity119 . DESIGN: A historical, retrospective, unrandomised study. SETTING: A tertiary referral centre. METHODS: Cardiac catheterisation was performed in all @entit... | [
"@entity119"
] |
126 | 127 | 128 | Ambulatory arterial stiffness indices and target organ damage in XXXX .
| multiple_choice | [
"@entity1",
"@entity8",
"@entity101",
"@entity123",
"@entity121",
"@entity122"
] | BACKGROUND: The present study was designed to evaluate which arterial stiffness parameter - AASI or the home arterial stiffness index (HASI) - correlates best with vascular, cardiac and @entity8 in @entity101 individuals. METHODS: A cross-sectional study was carried out involving 258 @entity101 @entity1 . AASI and HASI... | [
"@entity101"
] |
129 | 130 | 131 | Expression and clinical significance of Notch signaling genes in XXXX .
| multiple_choice | [
"@entity1",
"@entity124",
"@entity5",
"@entity125",
"@entity14",
"@entity127",
"@entity126"
] | The objective of this study was to explore the expression and clinical significance of Notch signaling genes in @entity14 . @entity14 samples were prospectively collected from @entity1 post-surgery at the 3rd Affiliated Hospital, Nanjing University of Traditional Chinese Medicine. Immunohistochemistry of tissue arrays ... | [
"@entity14"
] |
132 | 133 | 134 | Case studies on implant removal influencing the resolution of XXXX injury.
| multiple_choice | [
"@entity129",
"@entity1",
"@entity131",
"@entity132",
"@entity16",
"@entity128",
"@entity133",
"@entity134",
"@entity9",
"@entity130"
] | INTRODUCTION: @entity128 during implant placement is a preventable, serious complication with major medico-legal implications. The incidence of implant related @entity129 ( @entity129 ) @entity130 varies from 0-40%. This article presents four cases of @entity131 following mandibular implant placement with early removal... | [
"@entity129"
] |
135 | 136 | 137 | XXXX concurrent with radiation therapy for locally advanced @entity135 .
| multiple_choice | [
"@entity1",
"@entity135",
"@entity137",
"@entity138",
"@entity33",
"@entity136"
] | BACKGROUND: Management of advanced @entity135 is a challenging proposition. Presently concomitant chemo-irradiation has become the standard of care in such @entity1 . Many chemotherapeutic drugs have shown radio-sensitising effects when used concomitantly along with radiation. The present study was carried out with the... | [
"@entity136"
] |
138 | 139 | 140 | @entity136 concurrent with radiation therapy for locally advanced XXXX .
| multiple_choice | [
"@entity1",
"@entity135",
"@entity137",
"@entity138",
"@entity33",
"@entity136"
] | BACKGROUND: Management of advanced @entity135 is a challenging proposition. Presently concomitant chemo-irradiation has become the standard of care in such @entity1 . Many chemotherapeutic drugs have shown radio-sensitising effects when used concomitantly along with radiation. The present study was carried out with the... | [
"@entity135"
] |
141 | 142 | 143 | Switch to glutamate receptor 2-lacking @entity140 receptors increases neuronal excitability in hypothalamus and sympathetic drive in XXXX .
| multiple_choice | [
"@entity142",
"@entity101",
"@entity35",
"@entity144",
"@entity139",
"@entity140",
"@entity143",
"@entity141"
] | Glutamatergic synaptic input in the hypothalamic paraventricular nucleus (PVN) plays a critical role in regulating sympathetic outflow in @entity101 . @entity139 -lacking @entity140 receptors (AMPARs) are permeable to @entity141 , and their currents show unique inward rectification. However, little is known about chang... | [
"@entity101"
] |
144 | 145 | 146 | Switch to glutamate receptor 2-lacking XXXX receptors increases neuronal excitability in hypothalamus and sympathetic drive in @entity101 .
| multiple_choice | [
"@entity142",
"@entity101",
"@entity35",
"@entity144",
"@entity139",
"@entity140",
"@entity143",
"@entity141"
] | Glutamatergic synaptic input in the hypothalamic paraventricular nucleus (PVN) plays a critical role in regulating sympathetic outflow in @entity101 . @entity139 -lacking @entity140 receptors (AMPARs) are permeable to @entity141 , and their currents show unique inward rectification. However, little is known about chang... | [
"@entity140"
] |
147 | 148 | 149 | @entity149 in pediatric XXXX .
| multiple_choice | [
"@entity1",
"@entity146",
"@entity73",
"@entity149",
"@entity147",
"@entity145",
"@entity148",
"@entity130"
] | OBJECTIVE: This study aims to investigate whether @entity145 (AC) compromise neurocognitive function and psychological profiles in pediatric @entity1 , depending on various clinical factors. METHODS: We assessed neurocognitive functions and psychological tests in 35 AC @entity1 and 35 healthy control subjects between O... | [
"@entity145"
] |
150 | 151 | 152 | XXXX in pediatric @entity145 .
| multiple_choice | [
"@entity1",
"@entity146",
"@entity73",
"@entity149",
"@entity147",
"@entity145",
"@entity148",
"@entity130"
] | OBJECTIVE: This study aims to investigate whether @entity145 (AC) compromise neurocognitive function and psychological profiles in pediatric @entity1 , depending on various clinical factors. METHODS: We assessed neurocognitive functions and psychological tests in 35 AC @entity1 and 35 healthy control subjects between O... | [
"@entity149"
] |
153 | 154 | 155 | Prognostic value of histopathological @entity5 growth patterns at the invasion front of T1G3 XXXX .
| multiple_choice | [
"@entity5",
"@entity1",
"@entity150"
] | OBJECTIVE: The course of non-muscle-invasive @entity150 (BC) staged T1G3 is hardly predictable and treatment is subject of intensive debate. In muscle-invasive BC, the infiltrative growth pattern at the @entity5 invasion front was able to predict @entity1 ' survival, in contrast to the nodular and trabecular growth pat... | [
"@entity150"
] |
156 | 157 | 158 | Prognostic value of histopathological XXXX growth patterns at the invasion front of T1G3 @entity150 .
| multiple_choice | [
"@entity5",
"@entity1",
"@entity150"
] | OBJECTIVE: The course of non-muscle-invasive @entity150 (BC) staged T1G3 is hardly predictable and treatment is subject of intensive debate. In muscle-invasive BC, the infiltrative growth pattern at the @entity5 invasion front was able to predict @entity1 ' survival, in contrast to the nodular and trabecular growth pat... | [
"@entity5"
] |
159 | 160 | 161 | A clinicopathological study of peripheral, small-sized high-grade @entity5 of the lung: differences between small-cell lung carcinoma and XXXX .
| multiple_choice | [
"@entity5",
"@entity1",
"@entity151",
"@entity152"
] | OBJECTIVES: @entity151 ( @entity151 ) and @entity152 ( @entity152 ) are categorized as high-grade @entity5 because of their poor prognosis compared with those of other @entity5 of the lung. There have been no clinicopathological studies focusing on small-sized high-grade @entity5 . We analysed clinicopathological featu... | [
"@entity152"
] |
162 | 163 | 164 | A clinicopathological study of peripheral, small-sized high-grade XXXX of the lung: differences between small-cell lung carcinoma and @entity152 .
| multiple_choice | [
"@entity5",
"@entity1",
"@entity151",
"@entity152"
] | OBJECTIVES: @entity151 ( @entity151 ) and @entity152 ( @entity152 ) are categorized as high-grade @entity5 because of their poor prognosis compared with those of other @entity5 of the lung. There have been no clinicopathological studies focusing on small-sized high-grade @entity5 . We analysed clinicopathological featu... | [
"@entity5"
] |
165 | 166 | 167 | Extended cervical mediastinoscopy: mature results of a clinical protocol for staging XXXX of the left lung.
| multiple_choice | [
"@entity1",
"@entity5",
"@entity153",
"@entity66"
] | OBJECTIVE: The objective of this study is to evaluate the accuracy of extended cervical mediastinoscopy (ECM) in the staging of @entity153 ( @entity153 ) of the left lung based on our updated experience. METHODS: From 1998 to 2003, 89 @entity1 underwent routine ECM for staging of @entity153 of the left lung. In 2004, r... | [
"@entity153"
] |
168 | 169 | 170 | Treatment of XXXX injury of three fingers with a compound thoracodorsal artery perforator flap including serratus anterior fascia.
| multiple_choice | [
"@entity154",
"@entity155",
"@entity156",
"@entity130"
] | @entity130 not amenable to revascularization may leave poor cosmetic and functional results. We used a compound thoracodorsal artery perforator (TDAP) flap in a 34-year-old, right-handed, male worker with @entity130 . The flap consisted of a thin nonbulky skin component isolated on two perforators in combination with s... | [
"@entity155"
] |
171 | 172 | 173 | Clinical features and prognostic factors in @entity1 with bone @entity3 from XXXX receiving external beam radiotherapy.
| multiple_choice | [
"@entity1",
"@entity5",
"@entity79",
"@entity160",
"@entity158",
"@entity3",
"@entity157",
"@entity159"
] | BACKGROUND: The current study was performed to identify clinical features and independent predictors of survival in @entity1 with bone @entity3 from @entity157 ( @entity157 ). METHODS: @entity1 (n = 205) with bone @entity3 from @entity157 received external beam radiotherapy (EBRT) between 1997 and 2007. Demographic var... | [
"@entity157"
] |
174 | 175 | 176 | Clinical features and prognostic factors in @entity1 with bone XXXX from @entity157 receiving external beam radiotherapy.
| multiple_choice | [
"@entity1",
"@entity5",
"@entity79",
"@entity160",
"@entity158",
"@entity3",
"@entity157",
"@entity159"
] | BACKGROUND: The current study was performed to identify clinical features and independent predictors of survival in @entity1 with bone @entity3 from @entity157 ( @entity157 ). METHODS: @entity1 (n = 205) with bone @entity3 from @entity157 received external beam radiotherapy (EBRT) between 1997 and 2007. Demographic var... | [
"@entity3"
] |
177 | 178 | 179 | Clinical features and prognostic factors in XXXX with bone @entity3 from @entity157 receiving external beam radiotherapy.
| multiple_choice | [
"@entity1",
"@entity5",
"@entity79",
"@entity160",
"@entity158",
"@entity3",
"@entity157",
"@entity159"
] | BACKGROUND: The current study was performed to identify clinical features and independent predictors of survival in @entity1 with bone @entity3 from @entity157 ( @entity157 ). METHODS: @entity1 (n = 205) with bone @entity3 from @entity157 received external beam radiotherapy (EBRT) between 1997 and 2007. Demographic var... | [
"@entity1"
] |
180 | 181 | 182 | Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and XXXX .
| multiple_choice | [
"@entity162",
"@entity163",
"@entity146",
"@entity73",
"@entity161",
"@entity35"
] | BACKGROUND: Despite its estimated high heritability, the genetic architecture leading to differences in cognitive performance remains poorly understood. Different cortical regions play important roles in normal cognitive functioning and impairment. Recently, we reported on sets of regionally enriched genes in three dif... | [
"@entity146"
] |
183 | 184 | 185 | Targeting educational therapy for XXXX 2 @entity6 : identification of predictors of therapeutic success.
| multiple_choice | [
"@entity1",
"@entity165",
"@entity164",
"@entity6"
] | @entity1 education is a key component of @entity6 care. Limits in resources often prevent the participation of many @entity1 with @entity164 2 @entity6 to structured education programs. The identification of predictors of response to group education could help in selecting those @entity1 in whom the intervention is mor... | [
"@entity164"
] |
186 | 187 | 188 | Targeting educational therapy for @entity164 2 XXXX : identification of predictors of therapeutic success.
| multiple_choice | [
"@entity1",
"@entity165",
"@entity164",
"@entity6"
] | @entity1 education is a key component of @entity6 care. Limits in resources often prevent the participation of many @entity1 with @entity164 2 @entity6 to structured education programs. The identification of predictors of response to group education could help in selecting those @entity1 in whom the intervention is mor... | [
"@entity6"
] |
189 | 190 | 191 | Risk factors for non-communicable diseases in rural Uganda: a pilot surveillance project among XXXX @entity1 at a referral hospital clinic.
| multiple_choice | [
"@entity1",
"@entity101",
"@entity6",
"@entity28",
"@entity167",
"@entity168",
"@entity166"
] | INTRODUCTION: Despite an increasing recognition of @entity166 ( @entity166 ) in sub-Saharan Africa, there is lack of well established surveillance systems for these diseases. In an effort to understand burden of @entity166 in low-resource settings, the African Field Epidemiology Network launched a pilot project in 2009... | [
"@entity6"
] |
192 | 193 | 194 | Risk factors for non-communicable diseases in rural Uganda: a pilot surveillance project among @entity6 XXXX at a referral hospital clinic.
| multiple_choice | [
"@entity1",
"@entity101",
"@entity6",
"@entity28",
"@entity167",
"@entity168",
"@entity166"
] | INTRODUCTION: Despite an increasing recognition of @entity166 ( @entity166 ) in sub-Saharan Africa, there is lack of well established surveillance systems for these diseases. In an effort to understand burden of @entity166 in low-resource settings, the African Field Epidemiology Network launched a pilot project in 2009... | [
"@entity1"
] |
195 | 196 | 197 | XXXX : laparoscopic or inguinal approach. Decision making strategy: a prospective study.
| multiple_choice | [
"@entity1",
"@entity169"
] | The management of the contralateral region in a @entity1 with a known @entity169 is a debated issue among paediatric surgeons. The available literature indicates that the perspective of the @entity1 's parents is seldom. This study was performed to evaluate parents' views on this topic. After the Ethical Committee's ap... | [
"@entity169"
] |
198 | 199 | 200 | Individualizing XXXX therapy.
| multiple_choice | [
"@entity1",
"@entity172",
"@entity175",
"@entity178",
"@entity171",
"@entity174",
"@entity170",
"@entity177",
"@entity173",
"@entity176"
] | Guidelines for @entity170 treatment are available; however, these guidelines suggest when to treat @entity1 , without specific recommendations on what drugs to prescribe in various situations. Choice of @entity170 therapy should be individualized based on consideration of the efficacy, safety, cost, convenience (i.e., ... | [
"@entity170"
] |
201 | 202 | 203 | XXXX : outcomes of combined anterior and posterior pelvis surgery with minimum 2-year follow-up.
| multiple_choice | [
"@entity1",
"@entity85",
"@entity179",
"@entity158"
] | Combined anterior and posterior surgery is useful for fixed @entity85 . The specific indications for and clinical outcome parameters after combined surgery for @entity1 with @entity179 have not been well defined. We retrospectively reviewed 14 consecutive @entity1 with @entity179 treated with combined anterior and post... | [
"@entity179"
] |
204 | 205 | 206 | In vitro development and gene expression of frozen-thawed 8-cell stage XXXX embryos following slow freezing or vitrification.
| multiple_choice | [
"@entity181",
"@entity19",
"@entity180",
"@entity185",
"@entity184",
"@entity186",
"@entity187",
"@entity182",
"@entity183"
] | OBJECTIVE: This study was performed to compare the efficiency of slow freezing and vitrification based on survival, development to blastocysts, and cell numbers of blastocysts. Changes in embryonic gene expression in fresh and frozen-thawed embryos were also examined. METHODS: Eight-cell stage embryos were collected fr... | [
"@entity19"
] |
207 | 208 | 209 | Local excision of early XXXX : is transanal endoscopic microsurgery an alternative to radical surgery?
| multiple_choice | [
"@entity1",
"@entity190",
"@entity5",
"@entity189",
"@entity188"
] | OBJECTIVE: Transanal endoscopic microsurgery (TEM) allows locally complete excision of @entity188 and provides an alternative to conventional surgery for benign @entity5 . However, its role in the curative treatment of @entity189 is controversial. This paper examines the results of TEM compared with radical surgery (RS... | [
"@entity5"
] |
210 | 211 | 212 | Primary skin fibroblasts as a model of XXXX .
| multiple_choice | [
"@entity1",
"@entity5",
"@entity192",
"@entity191",
"@entity196",
"@entity193",
"@entity179",
"@entity194",
"@entity195"
] | @entity191 is the second most frequent @entity179 . While most cases occur sporadic mutations in a growing number of genes including Parkin ( @entity192 ) and @entity193 ( @entity193 ) have been associated with the disease. Different animal models and cell models like @entity1 skin fibroblasts and recombinant cell line... | [
"@entity191"
] |
213 | 214 | 215 | Repellent effect of Salvia dorisiana, S. longifolia, and S. sclarea (Lamiaceae) essential oils against the mosquito XXXX Skuse (Diptera: Culicidae).
| multiple_choice | [
"@entity1",
"@entity198",
"@entity199",
"@entity197",
"@entity200"
] | @entity197 (Diptera: Culicidae) has been one of the fastest spreading insects over the past 20 years. Its medical importance is due to the aggressive daytime @entity1 -biting behavior and the ability to vector many viruses, including dengue, LaCrosse, Eastern Equine @entity198 and West Nile viruses. In this research, t... | [
"@entity197"
] |
216 | 217 | 218 | Diffusion-weighted MR imaging for detection of XXXX .
| multiple_choice | [
"@entity1",
"@entity201",
"@entity5",
"@entity202"
] | OBJECTIVES: To measure the sensitivity of diffusion-weighted imaging (DWI) and determine the most appropriate b value for DWI; to explore the correlation between the apparent diffusion coefficient (ADC) value and the degree of @entity201 differentiation. METHODS: Preoperative diffusion-weighted imaging and magnetic res... | [
"@entity201"
] |
219 | 220 | 221 | XXXX : five years of treatment experience from a burn unit.
| multiple_choice | [
"@entity1",
"@entity137",
"@entity209",
"@entity203",
"@entity205",
"@entity208",
"@entity207",
"@entity210",
"@entity204",
"@entity206"
] | BACKGROUND: @entity137 ( @entity137 ) is a serious @entity203 that results in @entity204 in approximately 25% to 50% of @entity1 . There is controversy over whether SCORTEN accurately predicts mortality or if treatment interventions such as intravenous immunoglobulin (IVIg) can alter mortality. OBJECTIVES: We sought to... | [
"@entity137"
] |
222 | 223 | 224 | Lethal body residues for XXXX in zebra mussels (Dreissena polymorpha) under varying conditions of temperature and pH.
| multiple_choice | [
"@entity212",
"@entity211",
"@entity137"
] | @entity211 ( @entity212 ) @entity137 was measured in the zebra mussel under varying conditions of pH (6.5, 7.5, or 8.5) and temperature (10, 17, or 25 degrees C). @entity137 decreased significantly with increasing pH at all temperatures. At a given pH level, @entity137 increased significantly with increasing temperatur... | [
"@entity211"
] |
225 | 226 | 227 | Mass spectrometry-based salivary proteomics for the discovery of XXXX .
| multiple_choice | [
"@entity1",
"@entity217",
"@entity5",
"@entity215",
"@entity219",
"@entity216",
"@entity218",
"@entity214",
"@entity213"
] | The 5-year survival rates for cases of @entity213 ( @entity213 ) are only some 60%, mainly because 20%-40% of the @entity1 develop a local relapse in the same or an adjacent anatomic region, even when the surgical margins are histologically @entity5 -free. @entity5 are often discovered in an advanced stage because of t... | [
"@entity213"
] |
228 | 229 | 230 | Does IgE bind to and activate eosinophils from XXXX with allergy?
| multiple_choice | [
"@entity1",
"@entity222",
"@entity225",
"@entity56",
"@entity223",
"@entity224",
"@entity221",
"@entity220"
] | @entity1 eosinophils have been reported to express both the mRNA and protein for the high affinity IgE receptor ( @entity220 ); it is speculated that this receptor plays a role in eosinophil mediator release in @entity56 . However, questions still remain. How much of the @entity220 protein is actually expressed on the ... | [
"@entity1"
] |
231 | 232 | 233 | Visual performance in @entity226 ( XXXX ) after 1 year of therapy.
| multiple_choice | [
"@entity1",
"@entity227",
"@entity231",
"@entity229",
"@entity226",
"@entity228",
"@entity134",
"@entity230",
"@entity130"
] | AIMS: To determine if @entity1 with @entity226 ( @entity226 ) treated with corticosteroids develop delayed @entity227 or drug related ocular complications. METHODS: In a multicentre prospective study @entity1 with @entity226 (using precise diagnostic criteria) had ophthalmic evaluations at predetermined intervals up to... | [
"@entity226"
] |
234 | 235 | 236 | Visual performance in XXXX ( @entity226 ) after 1 year of therapy.
| multiple_choice | [
"@entity1",
"@entity227",
"@entity231",
"@entity229",
"@entity226",
"@entity228",
"@entity134",
"@entity230",
"@entity130"
] | AIMS: To determine if @entity1 with @entity226 ( @entity226 ) treated with corticosteroids develop delayed @entity227 or drug related ocular complications. METHODS: In a multicentre prospective study @entity1 with @entity226 (using precise diagnostic criteria) had ophthalmic evaluations at predetermined intervals up to... | [
"@entity226"
] |
237 | 238 | 239 | Serological and entomological survey of zoonotic XXXX in Denizli Province, Aegean Region, @entity233 .
| multiple_choice | [
"@entity1",
"@entity233",
"@entity235",
"@entity234",
"@entity232",
"@entity237",
"@entity236",
"@entity238"
] | A cross-sectional seroepidemiological survey of @entity232 was carried out among @entity1 and adults from four villages and one district of Denizli province located in the Southern Aegean Region of @entity233 where 14 @entity1 @entity234 (HVL) cases including 4 adults were reported between 1993 and 2000. Blood samples ... | [
"@entity234"
] |
240 | 241 | 242 | Serological and entomological survey of zoonotic @entity234 in Denizli Province, Aegean Region, XXXX .
| multiple_choice | [
"@entity1",
"@entity233",
"@entity235",
"@entity234",
"@entity232",
"@entity237",
"@entity236",
"@entity238"
] | A cross-sectional seroepidemiological survey of @entity232 was carried out among @entity1 and adults from four villages and one district of Denizli province located in the Southern Aegean Region of @entity233 where 14 @entity1 @entity234 (HVL) cases including 4 adults were reported between 1993 and 2000. Blood samples ... | [
"@entity233"
] |
243 | 244 | 245 | [Medicinal baths for treatment of generalized XXXX ].
| multiple_choice | [
"@entity1",
"@entity239",
"@entity240",
"@entity158"
] | OBJECTIVE: We studied whether whirl baths with plain water or with water containing pine oil or valerian have a different influence on @entity158 , disturbed sleep or tender point count. METHODS: A randomized, comparative and investigator-blinded study was performed. Out- @entity1 with generalized @entity239 were rando... | [
"@entity239"
] |
246 | 247 | 248 | [ XXXX : case report].
| multiple_choice | [
"@entity1",
"@entity82",
"@entity242",
"@entity5",
"@entity241",
"@entity243"
] | OBJECTIVE: @entity241 ( @entity241 ) is a relatively rare, slow-growing, fibrohistiocytic @entity242 of intermediate @entity5 . The @entity5 appears most frequently on the trunk and extremities as a slow-growing indurated plaque or nodule. It appears mostly between the second and fifth decades of life. METHODS: This is... | [
"@entity241"
] |
249 | 250 | 251 | Clinical Presentation of XXXX : Differences According to Age.
| multiple_choice | [
"@entity1",
"@entity249",
"@entity251",
"@entity248",
"@entity246",
"@entity245",
"@entity252",
"@entity247",
"@entity244",
"@entity250"
] | The aim of the study was to establish the characteristics of presentation of 94 @entity1 with @entity244 ( @entity244 ) referred to the endocrinologist at different ages. The diagnosis of @entity244 was more frequent in the age group between 11 and 20 years (46.8%). Most of the @entity1 (83.7%) showed the classic 47,XX... | [
"@entity252"
] |
252 | 253 | 254 | XXXX . Personal experience and technical notes.
| multiple_choice | [
"@entity1",
"@entity257",
"@entity254",
"@entity256",
"@entity253",
"@entity258",
"@entity255"
] | BACKGROUND: Benign @entity253 are a binding situation for clinicians when choosing the best treatment. This is a benign disease and needs safe, effective and lasting therapy. Up to day non surgical treatment have been suggested as the first therapeutical option but surgery seems to support the best late results. METHOD... | [
"@entity253"
] |
255 | 256 | 257 | [Conservative surgical treatment in XXXX ].
| multiple_choice | [
"@entity1",
"@entity66",
"@entity5",
"@entity260",
"@entity261",
"@entity3",
"@entity259"
] | BACKGROUND: Purpose of the present study was to compare survival of @entity1 affected by @entity259 after total and partial thyroidectomy. METHODS: The study has been carried in a retrospective way; mean follow-up has been 160 months. Surgical setting has been the Institute of Emergency Surgery at the University of Cat... | [
"@entity259"
] |
258 | 259 | 260 | MR imaging response of brain XXXX after gamma knife stereotactic radiosurgery.
| multiple_choice | [
"@entity1",
"@entity5",
"@entity75",
"@entity262",
"@entity3"
] | PURPOSE: To characterize the magnetic resonance (MR) imaging response of brain @entity3 after gamma knife stereotactic radiosurgery and determine whether imaging features and @entity5 response rates correlate with @entity5 control and survival. MATERIALS AND METHODS: Serial MR examinations were performed in 48 @entity1... | [
"@entity3"
] |
261 | 262 | 263 | Knowledge of symptoms and diagnostic possibilities of XXXX .
| multiple_choice | [
"@entity1",
"@entity263",
"@entity0",
"@entity5",
"@entity2",
"@entity14"
] | INTRODUCTION: The aim of the present study was to analyse @entity1 ' knowledge in the field of neoplastic prophylaxis. MATERIAL AND METHODS: The research was carried out between 2007 and 2008 in the Provincial Hospital in Bydgoszcz (i.e. general surgery, gynaecology and obstetrics, urology, breast surgery and thoracic ... | [
"@entity5"
] |
264 | 265 | 266 | Negative regulation of rat hepatic XXXX dehydrogenase 3 by glucocorticoids.
| multiple_choice | [
"@entity268",
"@entity269",
"@entity267",
"@entity266",
"@entity265",
"@entity264"
] | The expression of the @entity264 dehydrogenase 3 gene is known to be controlled by multiple regulatory processes. In liver, inducible expression appears to be mediated by two AhRE sequences which allow regulation of this gene by xenobiotic compounds which are ligands for the @entity265 (Takimoto et al., 1994; this work... | [
"@entity264"
] |
267 | 268 | 269 | Modulation of collagen synthesis and its gene expression in @entity1 skin fibroblasts by XXXX -rich fraction.
| multiple_choice | [
"@entity1",
"@entity274",
"@entity270",
"@entity271",
"@entity273",
"@entity272"
] | INTRODUCTION: Skin aging may occur as a result of increased free radicals in the body. @entity270 , the major chain-breaking antioxidant, prevents propagation of oxidative stress, especially in biological membranes. In this study, the molecular mechanism of @entity271 -rich fraction (TRF) in preventing oxidative stress... | [
"@entity271"
] |
270 | 271 | 272 | Modulation of collagen synthesis and its gene expression in XXXX skin fibroblasts by @entity271 -rich fraction.
| multiple_choice | [
"@entity1",
"@entity274",
"@entity270",
"@entity271",
"@entity273",
"@entity272"
] | INTRODUCTION: Skin aging may occur as a result of increased free radicals in the body. @entity270 , the major chain-breaking antioxidant, prevents propagation of oxidative stress, especially in biological membranes. In this study, the molecular mechanism of @entity271 -rich fraction (TRF) in preventing oxidative stress... | [
"@entity1"
] |
273 | 274 | 275 | Comparison of an @entity275 -impregnated collar with topical administration of XXXX for prevention of experimental and @entity277 by the @entity278 ( @entity278 ).
| multiple_choice | [
"@entity276",
"@entity235",
"@entity277",
"@entity275",
"@entity278"
] | OBJECTIVE: To compare the efficacies of @entity275 and @entity276 for prevention of experimental and @entity277 of @entity278 . DESIGN: Prospective study. ANIMALS: 30 @entity235 . PROCEDURE: In 3 trials, @entity235 were allocated to 3 groups of 10 each. In trial 1, @entity235 were experimentally infested on day--1, and... | [
"@entity276"
] |
276 | 277 | 278 | Comparison of an XXXX -impregnated collar with topical administration of @entity276 for prevention of experimental and @entity277 by the @entity278 ( @entity278 ).
| multiple_choice | [
"@entity276",
"@entity235",
"@entity277",
"@entity275",
"@entity278"
] | OBJECTIVE: To compare the efficacies of @entity275 and @entity276 for prevention of experimental and @entity277 of @entity278 . DESIGN: Prospective study. ANIMALS: 30 @entity235 . PROCEDURE: In 3 trials, @entity235 were allocated to 3 groups of 10 each. In trial 1, @entity235 were experimentally infested on day--1, and... | [
"@entity275"
] |
279 | 280 | 281 | Comparison of an @entity275 -impregnated collar with topical administration of @entity276 for prevention of experimental and XXXX by the @entity278 ( @entity278 ).
| multiple_choice | [
"@entity276",
"@entity235",
"@entity277",
"@entity275",
"@entity278"
] | OBJECTIVE: To compare the efficacies of @entity275 and @entity276 for prevention of experimental and @entity277 of @entity278 . DESIGN: Prospective study. ANIMALS: 30 @entity235 . PROCEDURE: In 3 trials, @entity235 were allocated to 3 groups of 10 each. In trial 1, @entity235 were experimentally infested on day--1, and... | [
"@entity277"
] |
282 | 283 | 284 | Comparison of an @entity275 -impregnated collar with topical administration of @entity276 for prevention of experimental and @entity277 by the XXXX ( @entity278 ).
| multiple_choice | [
"@entity276",
"@entity235",
"@entity277",
"@entity275",
"@entity278"
] | OBJECTIVE: To compare the efficacies of @entity275 and @entity276 for prevention of experimental and @entity277 of @entity278 . DESIGN: Prospective study. ANIMALS: 30 @entity235 . PROCEDURE: In 3 trials, @entity235 were allocated to 3 groups of 10 each. In trial 1, @entity235 were experimentally infested on day--1, and... | [
"@entity278"
] |
285 | 286 | 287 | Comparison of an @entity275 -impregnated collar with topical administration of @entity276 for prevention of experimental and @entity277 by the @entity278 ( XXXX ).
| multiple_choice | [
"@entity276",
"@entity235",
"@entity277",
"@entity275",
"@entity278"
] | OBJECTIVE: To compare the efficacies of @entity275 and @entity276 for prevention of experimental and @entity277 of @entity278 . DESIGN: Prospective study. ANIMALS: 30 @entity235 . PROCEDURE: In 3 trials, @entity235 were allocated to 3 groups of 10 each. In trial 1, @entity235 were experimentally infested on day--1, and... | [
"@entity278"
] |
288 | 289 | 290 | Surgical management of intramedullary XXXX of the spinal cord.
| multiple_choice | [
"@entity1",
"@entity279",
"@entity5",
"@entity75",
"@entity51",
"@entity281",
"@entity158",
"@entity282",
"@entity280"
] | This is a study on 19 @entity1 , who underwent complete excision of an intramedullary @entity279 of the spinal cord during the period 1984-1997. The study was conducted to evaluate their functional outcome. Some peculiarities of their clinical presentation and surgical treatment are discussed as well. There were 12 mal... | [
"@entity279"
] |
291 | 292 | 293 | XXXX and multimorbidity among problem drug users: a comparative cross sectional pilot study in primary care.
| multiple_choice | [
"@entity1",
"@entity284",
"@entity283",
"@entity102"
] | BACKGROUND: Although multimorbidity has important implications for @entity1 care in general practice, limited research has examined @entity102 and @entity283 service utilisation among problem drug users. This study aimed to determine @entity102 prevalence and @entity283 service utilisation among problem drug users atte... | [
"@entity102"
] |
Dataset Card for BIOMRC
We introduce BIOMRC, a large-scale cloze-style biomedical MRC dataset. Care was taken to reduce noise, compared to the previous BIOREAD dataset of Pappas et al. (2018). Experiments show that simple heuristics do not perform well on the new dataset and that two neural MRC models that had been tested on BIOREAD perform much better on BIOMRC, indicating that the new dataset is indeed less noisy or at least that its task is more feasible. Non-expert human performance is also higher on the new dataset compared to BIOREAD, and biomedical experts perform even better. We also introduce a new BERT-based MRC model, the best version of which substantially outperforms all other methods tested, reaching or surpassing the accuracy of biomedical experts in some experiments. We make the new dataset available in three different sizes, also releasing our code, and providing a leaderboard.
Citation Information
@inproceedings{pappas-etal-2020-biomrc,
title = "{B}io{MRC}: A Dataset for Biomedical Machine Reading Comprehension",
author = "Pappas, Dimitris and
Stavropoulos, Petros and
Androutsopoulos, Ion and
McDonald, Ryan",
booktitle = "Proceedings of the 19th SIGBioMed Workshop on Biomedical Language Processing",
month = jul,
year = "2020",
address = "Online",
publisher = "Association for Computational Linguistics",
url = "https://www.aclweb.org/anthology/2020.bionlp-1.15",
pages = "140--149",
}
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