id stringlengths 1 7 | question_id stringlengths 1 7 | document_id stringlengths 1 7 | question stringlengths 12 382 | type stringclasses 1
value | choices list | context stringlengths 423 3.87k | answer list |
|---|---|---|---|---|---|---|---|
2099700 | 2099701 | 2099702 | Inhibition of XXXX -3 kinase y reduces pruriceptive, inflammatory, and nociceptive responses induced by trypsin in @entity19 .
| multiple_choice | [
"@entity3115",
"@entity39",
"@entity19",
"@entity4",
"@entity5",
"@entity2951",
"@entity48750",
"@entity111",
"@entity9830",
"@entity53863",
"@entity4357"
] | This study investigated the effects of pharmacological inhibition of @entity4357 3-kinase ( @entity3115 )y in the pruriceptive, inflammatory, and nociceptive responses induced by trypsin in @entity19 . The animals were orally treated with the selective PI3Ky inhibitor @entity48750 (0.3-30 mg/kg) 30 minutes beforehand. ... | [
"@entity4357"
] |
2099703 | 2099704 | 2099705 | Inhibition of @entity4357 -3 kinase y reduces pruriceptive, inflammatory, and nociceptive responses induced by trypsin in XXXX .
| multiple_choice | [
"@entity3115",
"@entity39",
"@entity19",
"@entity4",
"@entity5",
"@entity2951",
"@entity48750",
"@entity111",
"@entity9830",
"@entity53863",
"@entity4357"
] | This study investigated the effects of pharmacological inhibition of @entity4357 3-kinase ( @entity3115 )y in the pruriceptive, inflammatory, and nociceptive responses induced by trypsin in @entity19 . The animals were orally treated with the selective PI3Ky inhibitor @entity48750 (0.3-30 mg/kg) 30 minutes beforehand. ... | [
"@entity19"
] |
2099706 | 2099707 | 2099708 | Secondary prevention in XXXX : goal achievement and drug prescribing.
| multiple_choice | [
"@entity1",
"@entity6",
"@entity301",
"@entity117",
"@entity165"
] | OBJECTIVE: To provide an overview of the degree of treatment goal achievement and drug prescribing in @entity1 with @entity301 ( @entity301 ) in clinical practice. METHOD: @entity1 undergoing planned or acute percutaneous coronary intervention (PCI) were included. @entity1 ' medical records and the hospital's database ... | [
"@entity301"
] |
2099709 | 2099710 | 2099711 | XXXX , an indicator of renal tubular maturation and dysfunction in the newborn.
| multiple_choice | [
"@entity1",
"@entity519",
"@entity2262",
"@entity3638"
] | The urinary excretion and proximal tubular reabsorption of @entity2262 was studied in 17 healthy newborn @entity1 in relation to gestational and post-natal age. The effect of IRDS and non-conjugated @entity3638 on the tubular reabsorption of the protein was evaluated in 10 IRDS @entity1 and 14 @entity1 with non-conjuga... | [
"@entity2262"
] |
2099712 | 2099713 | 2099714 | [Primary XXXX : clinicopathologic features and genetic alterations].
| multiple_choice | [
"@entity12624",
"@entity1071",
"@entity588",
"@entity706",
"@entity4592",
"@entity5",
"@entity242",
"@entity1074",
"@entity517",
"@entity4910",
"@entity4042",
"@entity1892",
"@entity12293",
"@entity11987",
"@entity7513"
] | OBJECTIVE: To investigate clinicopathological and genetic characteristics of primary @entity1071 . METHODS: Clinical, morphological and immunohistochemical features of 37 archival cases of primary @entity1071 were studied including 5 cases of @entity12293 and 32 @entity706 retrospectively. Classification of the @entity... | [
"@entity1071"
] |
2099715 | 2099716 | 2099717 | The hidden costs and characteristics of XXXX in Canada.
| multiple_choice | [
"@entity1",
"@entity341",
"@entity391",
"@entity294",
"@entity6425"
] | BACKGROUND: Administrative databases are often used to determine burden of @entity6425 in @entity341 ( @entity341 ). Our objective was to describe rotavirus ED visits to include healthcare utilization pre- and postvisit to estimate true societal costs. METHODS: During rotavirus seasons in 2007, 2008, and 2009, a conven... | [
"@entity6425"
] |
2099718 | 2099719 | 2099720 | Long-term tympanic membrane pathology dynamics and spontaneous healing in XXXX media.
| multiple_choice | [
"@entity1",
"@entity66",
"@entity102",
"@entity14360",
"@entity194",
"@entity2169",
"@entity2346"
] | BACKGROUND: @entity1 in the developing parts of the world have a high prevalence of @entity102 media (CSOM). It is estimated that 65 to 330 million @entity1 worldwide have CSOM, yet very little is known about the natural course of the disease. The Inuit population of the Arctic regions is among those with the highest p... | [
"@entity102"
] |
2099721 | 2099722 | 2099723 | [Diagnostic values of double-balloon enteroscopy and abdominal computed tomography in XXXX ].
| multiple_choice | [
"@entity1",
"@entity455",
"@entity1127",
"@entity706",
"@entity29",
"@entity420",
"@entity7261",
"@entity1820",
"@entity30"
] | OBJECTIVE: To evaluate the diagnostic values of double-balloon enteroscopy (DBE) and abdominal computed tomography (CT) in @entity29 . METHODS: Seventy eight DBE procedures were carried out in 70 @entity1 , 40 males and 30 females; aged 47.7 (16 - 83) with suspected @entity29 , all of whom received gastroscopy, colonos... | [
"@entity29"
] |
2099724 | 2099725 | 2099726 | Oral corticosteroid trials in the management of stable XXXX .
| multiple_choice | [
"@entity1",
"@entity2715",
"@entity3045",
"@entity1030",
"@entity617",
"@entity288"
] | Although recent guidelines for managing @entity1030 ( @entity1030 ) recommend a trial of oral @entity288 in the initial assessment, its prognostic value remains unclear. We prospectively studied 127 adults (64% @entity1 ) with stable @entity1030 (FEV1/FVC < 60%) over 1 year. At entry, we measured lung volumes, gas tran... | [
"@entity1030"
] |
2099727 | 2099728 | 2099729 | [Biochemical modulation of XXXX --effect of low dose CDDP].
| multiple_choice | [
"@entity1",
"@entity788",
"@entity5",
"@entity900",
"@entity1820",
"@entity418",
"@entity694",
"@entity1487"
] | A pilot study of continuous or intermittent low dose @entity1487 and @entity900 chemotherapy (low-dose FP therapy) was conducted at the Department of Surgery of Sapporo Medical University School of Medicine (Group A) and Sapporo Tsukisamu Hospital, and at the Department of Internal Medicine of the Kochi Prefectural Cen... | [
"@entity1487"
] |
2099730 | 2099731 | 2099732 | [The control survey in XXXX marker analysis of leukemic cells].
| multiple_choice | [
"@entity1",
"@entity981",
"@entity5",
"@entity1050",
"@entity3138",
"@entity1778",
"@entity10706",
"@entity1860"
] | Analysis of cell surface antigens is thought to be more objective compared to classification by the morphology. However, it has been indicated that the evaluated data are different each other between institutes. Therefore, we performed a control survey of @entity1050 marker analysis in @entity1778 cells using flow cyto... | [
"@entity1050"
] |
2099733 | 2099734 | 2099735 | How to improve the cardiac prognosis for XXXX .
| multiple_choice | [
"@entity1",
"@entity844",
"@entity583",
"@entity6",
"@entity63",
"@entity117",
"@entity741",
"@entity299",
"@entity413",
"@entity453",
"@entity204",
"@entity65"
] | @entity65 is a leading cause of @entity204 in @entity6 @entity1 . It has been reported to count for almost 80% of all @entity204 . About three-fourths of these @entity204 result from @entity453 . Studies have shown that @entity6 @entity1 who have had an @entity583 ( @entity583 ) have a mortality of about twice that of ... | [
"@entity6"
] |
2099736 | 2099737 | 2099738 | XXXX : analysis of 14 cases.
| multiple_choice | [
"@entity1",
"@entity3553",
"@entity1276",
"@entity391",
"@entity2972",
"@entity260",
"@entity325",
"@entity10",
"@entity221"
] | OBJECT: Pediatric cases of @entity3553 (SDE) are both rare and associated with high rates of morbidity and mortality. The goal of this study was to report @entity1 characteristics, treatment, and outcome in an exclusively pediatric series of SDE cases. METHODS: A series of 14 pediatric cases of infratentorial SDE was r... | [
"@entity3553"
] |
2099739 | 2099740 | 2099741 | Pathological, immunohistochemical, and in-situ hybridization studies of natural cases of @entity22131 ( XXXX ) in @entity1707 .
| multiple_choice | [
"@entity1707",
"@entity706",
"@entity75",
"@entity22131",
"@entity358",
"@entity1485",
"@entity1986",
"@entity401",
"@entity2275"
] | Fifteen @entity1707 from five farms on which there had been a previous clinical and histopathological diagnosis of @entity22131 ( @entity22131 ) were investigated. At necropsy, enlargement of lymph nodes was the most obvious lesion; other lesions were non-collapsed lungs, @entity2275 oesophagica, and @entity358 . @enti... | [
"@entity22131"
] |
2099742 | 2099743 | 2099744 | Pathological, immunohistochemical, and in-situ hybridization studies of natural cases of XXXX ( @entity22131 ) in @entity1707 .
| multiple_choice | [
"@entity1707",
"@entity706",
"@entity75",
"@entity22131",
"@entity358",
"@entity1485",
"@entity1986",
"@entity401",
"@entity2275"
] | Fifteen @entity1707 from five farms on which there had been a previous clinical and histopathological diagnosis of @entity22131 ( @entity22131 ) were investigated. At necropsy, enlargement of lymph nodes was the most obvious lesion; other lesions were non-collapsed lungs, @entity2275 oesophagica, and @entity358 . @enti... | [
"@entity22131"
] |
2099745 | 2099746 | 2099747 | Pathological, immunohistochemical, and in-situ hybridization studies of natural cases of @entity22131 ( @entity22131 ) in XXXX .
| multiple_choice | [
"@entity1707",
"@entity706",
"@entity75",
"@entity22131",
"@entity358",
"@entity1485",
"@entity1986",
"@entity401",
"@entity2275"
] | Fifteen @entity1707 from five farms on which there had been a previous clinical and histopathological diagnosis of @entity22131 ( @entity22131 ) were investigated. At necropsy, enlargement of lymph nodes was the most obvious lesion; other lesions were non-collapsed lungs, @entity2275 oesophagica, and @entity358 . @enti... | [
"@entity1707"
] |
2099748 | 2099749 | 2099750 | The @entity921 -responsive repressor Mur of XXXX is a member of the Fur-superfamily that recognizes an unusual operator sequence.
| multiple_choice | [
"@entity19063",
"@entity8798",
"@entity921",
"@entity3281",
"@entity14441",
"@entity19062",
"@entity68"
] | The @entity921 uptake regulator Mur of @entity14441 is a close homologue of the global @entity68 regulatory protein Fur. Mur represses the sitABCD operon, which encodes a @entity3281 transport system, specifically in response to @entity3281 but not @entity8798 . In previous work the authors mapped the 5' ends of two si... | [
"@entity14441"
] |
2099751 | 2099752 | 2099753 | The XXXX -responsive repressor Mur of @entity14441 is a member of the Fur-superfamily that recognizes an unusual operator sequence.
| multiple_choice | [
"@entity19063",
"@entity8798",
"@entity921",
"@entity3281",
"@entity14441",
"@entity19062",
"@entity68"
] | The @entity921 uptake regulator Mur of @entity14441 is a close homologue of the global @entity68 regulatory protein Fur. Mur represses the sitABCD operon, which encodes a @entity3281 transport system, specifically in response to @entity3281 but not @entity8798 . In previous work the authors mapped the 5' ends of two si... | [
"@entity921"
] |
2099754 | 2099755 | 2099756 | The efficacy and safety of adjunct XXXX therapy for levodopa-induced motor complications: a systematic review.
| multiple_choice | [
"@entity1",
"@entity2847",
"@entity191",
"@entity717",
"@entity551"
] | OBJECTIVES: To assess the efficacy and safety of adjunct @entity2847 (BR) compared with placebo in the treatment of @entity1 with @entity191 ( @entity191 ) who have motor complications. DESIGN: A systematic review of the literature from 1966-1999 on randomized, controlled trials. Outcome measures were occurrence and se... | [
"@entity2847"
] |
2099757 | 2099758 | 2099759 | Interaction of zwitterionic XXXX with the OmpF channel facilitates their translocation.
| multiple_choice | [
"@entity115",
"@entity114",
"@entity17286",
"@entity8545",
"@entity7911",
"@entity3400",
"@entity869"
] | To study translocation of @entity8545 antibiotics of different size and charge across the outer bacterial membrane, we combine an analysis of ion currents through single trimeric outer membrane protein F (OmpF) porins in planar lipid bilayers with molecular dynamics simulations. Because the size of @entity114 molecules... | [
"@entity114"
] |
2099760 | 2099761 | 2099762 | [ XXXX treatment with @entity64 unit and rehabilitation by a team. A model for a staged management].
| multiple_choice | [
"@entity1",
"@entity64",
"@entity1779"
] | This is a report of an interdisciplinary approach to diagnosis and treatment of @entity64 , combining a @entity64 unit and rehabilitation in one clinic. This series contains unselected @entity1 from a narrow surrounding. Mean age of 559 @entity1 was 68.7 years (median 70 years). 25% of @entity1 had an initial Barthel i... | [
"@entity64"
] |
2099763 | 2099764 | 2099765 | [ @entity64 treatment with XXXX unit and rehabilitation by a team. A model for a staged management].
| multiple_choice | [
"@entity1",
"@entity64",
"@entity1779"
] | This is a report of an interdisciplinary approach to diagnosis and treatment of @entity64 , combining a @entity64 unit and rehabilitation in one clinic. This series contains unselected @entity1 from a narrow surrounding. Mean age of 559 @entity1 was 68.7 years (median 70 years). 25% of @entity1 had an initial Barthel i... | [
"@entity64"
] |
2099766 | 2099767 | 2099768 | An audit of the effect of intravenous antibiotic treatment on spirometric measures of pulmonary function in XXXX .
| multiple_choice | [
"@entity1",
"@entity1729",
"@entity1577"
] | BACKGROUND: This retrospective audit was undertaken to compare the efficacy of home intravenous (i.v.) antibiotic therapy, hospital i.v. antibiotic therapy and a combination of these 2 approaches, as determined by spirometric measures of lung function in @entity1577 ( @entity1577 ) @entity1 , each with an acute respira... | [
"@entity1577"
] |
2099769 | 2099770 | 2099771 | Effect of the Glycine Antagonist Gavestinel on cerebral infarcts in XXXX @entity1 , a randomized placebo-controlled trial: The GAIN MRI Substudy.
| multiple_choice | [
"@entity1",
"@entity64",
"@entity1024",
"@entity2228",
"@entity63",
"@entity2806",
"@entity44844",
"@entity1188"
] | BACKGROUND AND PURPOSE: Gavestinel, @entity44844 , is a selective antagonist at the @entity2228 site of the @entity1024 receptor. The safety and efficacy of @entity44844 were studied in two phase III randomized placebo-controlled clinical trials of acute @entity63 @entity64 @entity1 within 6 h from onset [The Glycine A... | [
"@entity64"
] |
2099772 | 2099773 | 2099774 | Effect of the Glycine Antagonist Gavestinel on cerebral infarcts in @entity64 XXXX , a randomized placebo-controlled trial: The GAIN MRI Substudy.
| multiple_choice | [
"@entity1",
"@entity64",
"@entity1024",
"@entity2228",
"@entity63",
"@entity2806",
"@entity44844",
"@entity1188"
] | BACKGROUND AND PURPOSE: Gavestinel, @entity44844 , is a selective antagonist at the @entity2228 site of the @entity1024 receptor. The safety and efficacy of @entity44844 were studied in two phase III randomized placebo-controlled clinical trials of acute @entity63 @entity64 @entity1 within 6 h from onset [The Glycine A... | [
"@entity1"
] |
2099775 | 2099776 | 2099777 | XXXX : diagnosis and treatment.
| multiple_choice | [
"@entity1",
"@entity378",
"@entity5651",
"@entity1374"
] | OBJECTIVE: It was the aim of this study to report clinical characteristics and treatment of @entity1374 ( @entity1374 ). METHODS: During 16 years, 2,426 @entity1 have been operated on the thyroid in the surgical department 'A' in Ibn Sina Hospital, Rabat, Morocco. Anatomopathological results of the removed thyroid were... | [
"@entity1374"
] |
2099778 | 2099779 | 2099780 | Identification of differentially expressed genes between fetal and adult XXXX kidney: candidate gene in kidney development.
| multiple_choice | [
"@entity19",
"@entity52366"
] | BACKGROUND: The kidney development involves a wide variety of developmental processes requiring a lot of genes expressed in a sequential manner. The aim of the present study is to identify new genes involved in these processes. METHODS: To obtain a view of the @entity19 embryonic kidney transcriptome we used the SADE m... | [
"@entity19"
] |
2099781 | 2099782 | 2099783 | Mutations in 12 genes for inherited ovarian, fallopian tube, and XXXX identified by massively parallel sequencing.
| multiple_choice | [
"@entity1",
"@entity43",
"@entity15125",
"@entity15124",
"@entity5344",
"@entity9517",
"@entity5345",
"@entity5",
"@entity2674",
"@entity24717",
"@entity189",
"@entity876",
"@entity36524",
"@entity9485",
"@entity9518",
"@entity4638",
"@entity9516"
] | Inherited loss-of-function mutations in @entity5345 and @entity2674 and other @entity5 suppressor genes predispose to @entity43 , but the overall burden of disease due to inherited mutations is not known. Using targeted capture and massively parallel genomic sequencing, we screened for germ-line mutations in 21 @entity... | [
"@entity189"
] |
2099784 | 2099785 | 2099786 | XXXX in @entity1 : an epidemiological study at Kathmandu Medical College Teaching Hospital Kathmandu.
| multiple_choice | [
"@entity1",
"@entity410",
"@entity302"
] | OBJECTIVES: To analyze the relative frequencies of various @entity302 and to study the age at onset of different @entity410 types in Nepalese @entity1 . DESIGN: Prospective study. SETTING: Hospital outpatient based in Kathmandu, Nepal, between November 2001 to October 2002. @entity1 : 50 @entity1 diagnosed as @entity41... | [
"@entity302"
] |
2099787 | 2099788 | 2099789 | @entity302 in XXXX : an epidemiological study at Kathmandu Medical College Teaching Hospital Kathmandu.
| multiple_choice | [
"@entity1",
"@entity410",
"@entity302"
] | OBJECTIVES: To analyze the relative frequencies of various @entity302 and to study the age at onset of different @entity410 types in Nepalese @entity1 . DESIGN: Prospective study. SETTING: Hospital outpatient based in Kathmandu, Nepal, between November 2001 to October 2002. @entity1 : 50 @entity1 diagnosed as @entity41... | [
"@entity1"
] |
2099790 | 2099791 | 2099792 | Radiofrequency for the treatment of XXXX .
| multiple_choice | [
"@entity1",
"@entity25488",
"@entity8968"
] | OBJECTIVES: We assessed the efficacy of submucosal application of radiofrequency to the inferior turbinate for the treatment of @entity25488 . @entity1 AND METHODS: Twenty @entity1 with @entity25488 (9 males, 11 females; mean age 29.2 years; range 20 to 40 years) were treated with radiofrequency applied to the inferior... | [
"@entity25488"
] |
2099793 | 2099794 | 2099795 | Increased serum XXXX levels in chronic stage of @entity385 .
| multiple_choice | [
"@entity1",
"@entity407",
"@entity64",
"@entity101",
"@entity6",
"@entity2299",
"@entity1234",
"@entity1188",
"@entity1865",
"@entity385"
] | Serum lipoperoxidation products such as @entity1234 ( @entity1865 ) reflect oxidative stress. There are contradictory results addressing the levels of lipoperoxidation products in chronic phase of @entity385 . In the present study, we aimed to determine the serum @entity1865 levels in @entity64 @entity1 6 months after ... | [
"@entity1234"
] |
2099796 | 2099797 | 2099798 | Increased serum @entity1234 levels in chronic stage of XXXX .
| multiple_choice | [
"@entity1",
"@entity407",
"@entity64",
"@entity101",
"@entity6",
"@entity2299",
"@entity1234",
"@entity1188",
"@entity1865",
"@entity385"
] | Serum lipoperoxidation products such as @entity1234 ( @entity1865 ) reflect oxidative stress. There are contradictory results addressing the levels of lipoperoxidation products in chronic phase of @entity385 . In the present study, we aimed to determine the serum @entity1865 levels in @entity64 @entity1 6 months after ... | [
"@entity385"
] |
2099799 | 2099800 | 2099801 | [The prevalence of XXXX among health-care workers--a three-country comparison].
| multiple_choice | [
"@entity1",
"@entity9178",
"@entity281",
"@entity1906",
"@entity378",
"@entity166"
] | INTRODUCTION: Health-care workers are regularly screened for @entity378 . To date, there has been no systematic analysis of the results of such a screening. A @entity1906 network for company doctors was created when interferon-y release assays (IGRAs) were introduced in order to systematically collate their experience ... | [
"@entity9178"
] |
2099802 | 2099803 | 2099804 | Malignant XXXX in eye.
| multiple_choice | [
"@entity1",
"@entity6196",
"@entity2194",
"@entity1539",
"@entity548",
"@entity39",
"@entity5",
"@entity730",
"@entity1358",
"@entity158"
] | Malignant @entity6196 is an extremely rare @entity5 occurring in @entity1 younger than 5 years of age, arising from ciliary body epithelium or @entity1539 but few arise from optic nerve and retina. This report concerns a 5 years old @entity1 who presented with @entity158 , @entity2194 . Histopathologically, the @entity... | [
"@entity6196"
] |
2099805 | 2099806 | 2099807 | Survival impact of XXXX phenotypes.
| multiple_choice | [
"@entity14380",
"@entity788",
"@entity5",
"@entity9608",
"@entity4292",
"@entity7581",
"@entity189",
"@entity11563",
"@entity3270",
"@entity1349",
"@entity12983"
] | BACKGROUND: The low incidence of @entity14380 (ICTs) of the pancreas represents a challenge to precise post-therapeutic survival prediction. This study examined the survival impact of malignant @entity788 . METHODS: A pancreatic ICT data set was created from a US-based population database from 1980-2004. Prognostic fac... | [
"@entity788"
] |
2099808 | 2099809 | 2099810 | [A common and insidious side-effect: XXXX caused by bufexamac used in the treatment of @entity1909 . Results from the Information Network of Departments of Dermatology (IDVK)].
| multiple_choice | [
"@entity1",
"@entity483",
"@entity3408",
"@entity566",
"@entity1909",
"@entity484"
] | BACKGROUND AND OBJECTIVE: Bufexamac is a non-steroidal, anti-inflammatory drug used in the topical treatment of @entity483 , @entity1909 and @entity484 . The substance is known to cause severe @entity3408 ( @entity3408 ) as an adverse effect (AE), which may be indistinguishable from the @entity484 which is to be treate... | [
"@entity3408"
] |
2099811 | 2099812 | 2099813 | [A common and insidious side-effect: @entity3408 caused by bufexamac used in the treatment of XXXX . Results from the Information Network of Departments of Dermatology (IDVK)].
| multiple_choice | [
"@entity1",
"@entity483",
"@entity3408",
"@entity566",
"@entity1909",
"@entity484"
] | BACKGROUND AND OBJECTIVE: Bufexamac is a non-steroidal, anti-inflammatory drug used in the topical treatment of @entity483 , @entity1909 and @entity484 . The substance is known to cause severe @entity3408 ( @entity3408 ) as an adverse effect (AE), which may be indistinguishable from the @entity484 which is to be treate... | [
"@entity1909"
] |
2099814 | 2099815 | 2099816 | Minimally invasive plate osteosynthesis using anterior-inferior plating of clavicular midshaft XXXX .
| multiple_choice | [
"@entity1",
"@entity1183",
"@entity3",
"@entity174"
] | INTRODUCTION: This study evaluated the clinical and radiological outcomes of acute displaced clavicular midshaft @entity174 treated with @entity3 ( @entity3 ). MATERIALS AND METHODS: Fifteen @entity1 with acute displaced clavicular midshaft @entity174 underwent @entity3 . A locking reconstruction plate was applied on t... | [
"@entity174"
] |
2099817 | 2099818 | 2099819 | Ethnic disparity in XXXX and maternal pre-pregnancy body mass index.
| multiple_choice | [
"@entity1",
"@entity1017",
"@entity28",
"@entity600"
] | PURPOSE: To investigate differences in pre-pregnancy BMI status in @entity1 with @entity600 (PTB) compared with term birth and assess the role of ethnicity as a risk modifier in BMI-associated PTB. METHODS: A case-control study involving self-reported African American and Caucasian @entity1 delivering singletons in Nas... | [
"@entity600"
] |
2099820 | 2099821 | 2099822 | Neuroendocrine responses following graded XXXX in male adults.
| multiple_choice | [
"@entity1",
"@entity251",
"@entity131",
"@entity3614",
"@entity130",
"@entity75",
"@entity542",
"@entity1955",
"@entity2982",
"@entity6075",
"@entity701",
"@entity1230",
"@entity1954"
] | In an effort to characterize thyroid, gonadal and adrenal function following neurotrauma, the present study determined serum concentrations of thyroid-stimulating hormone (TSH), total @entity1954 (T3), @entity1955 (T4), @entity251 and @entity701 over a 7 day period in 31 @entity1 with @entity131 . The study group consi... | [
"@entity131"
] |
2099823 | 2099824 | 2099825 | Preliminary results of integrated therapy for @entity1 with XXXX .
| multiple_choice | [
"@entity1",
"@entity626",
"@entity571",
"@entity6661",
"@entity158"
] | OBJECTIVE: To investigate the effects of integrated therapy on the functional status of @entity1 with @entity626 ( @entity571 ). METHODS: A total of 140 subjects with bilateral knee @entity571 (Altman grade II) were randomized sequentially into 4 groups (groups I-IV). Group I received isokinetic exercises; group II rec... | [
"@entity626"
] |
2099826 | 2099827 | 2099828 | Preliminary results of integrated therapy for XXXX with @entity626 .
| multiple_choice | [
"@entity1",
"@entity626",
"@entity571",
"@entity6661",
"@entity158"
] | OBJECTIVE: To investigate the effects of integrated therapy on the functional status of @entity1 with @entity626 ( @entity571 ). METHODS: A total of 140 subjects with bilateral knee @entity571 (Altman grade II) were randomized sequentially into 4 groups (groups I-IV). Group I received isokinetic exercises; group II rec... | [
"@entity1"
] |
2099829 | 2099830 | 2099831 | Diagnostic value of single-photon-emission computed tomography in severe central nervous system involvement of XXXX : a case-control study.
| multiple_choice | [
"@entity1",
"@entity548",
"@entity1252",
"@entity854",
"@entity385"
] | OBJECTIVE: To evaluate the diagnostic value of single-photon-emission computed tomography (SPECT) in severe central nervous system (CNS) involvement of @entity1252 ( @entity1252 ). METHODS: Forty-three @entity1 with @entity1252 , including 22 with CNS- @entity1252 and 21 with non-CNS- @entity1252 , underwent SPECT and ... | [
"@entity1252"
] |
2099832 | 2099833 | 2099834 | Phase II study of XXXX , @entity900 , and @entity416 for advanced biliary tract adenocarcinoma.
| multiple_choice | [
"@entity1",
"@entity137",
"@entity416",
"@entity1259",
"@entity900",
"@entity33",
"@entity201",
"@entity1419",
"@entity1086",
"@entity1125"
] | BACKGROUND: @entity1125 (BTCs) are associated with a very poor prognosis. New therapeutic strategies therefore are needed to improve efficacy and survival, and the current study was designed with a new, effective drug combination. METHODS: @entity1 with recurrent or metastatic BTC received a combination of @entity1259 ... | [
"@entity1259"
] |
2099835 | 2099836 | 2099837 | Phase II study of @entity1259 , XXXX , and @entity416 for advanced biliary tract adenocarcinoma.
| multiple_choice | [
"@entity1",
"@entity137",
"@entity416",
"@entity1259",
"@entity900",
"@entity33",
"@entity201",
"@entity1419",
"@entity1086",
"@entity1125"
] | BACKGROUND: @entity1125 (BTCs) are associated with a very poor prognosis. New therapeutic strategies therefore are needed to improve efficacy and survival, and the current study was designed with a new, effective drug combination. METHODS: @entity1 with recurrent or metastatic BTC received a combination of @entity1259 ... | [
"@entity900"
] |
2099838 | 2099839 | 2099840 | Phase II study of @entity1259 , @entity900 , and XXXX for advanced biliary tract adenocarcinoma.
| multiple_choice | [
"@entity1",
"@entity137",
"@entity416",
"@entity1259",
"@entity900",
"@entity33",
"@entity201",
"@entity1419",
"@entity1086",
"@entity1125"
] | BACKGROUND: @entity1125 (BTCs) are associated with a very poor prognosis. New therapeutic strategies therefore are needed to improve efficacy and survival, and the current study was designed with a new, effective drug combination. METHODS: @entity1 with recurrent or metastatic BTC received a combination of @entity1259 ... | [
"@entity416"
] |
2099841 | 2099842 | 2099843 | The novel @entity588 inhibitor @entity2427 is more effective in @entity519 and is able to reverse XXXX -induced drug resistance in @entity521 cells.
| multiple_choice | [
"@entity7738",
"@entity588",
"@entity5",
"@entity1836",
"@entity2423",
"@entity1149",
"@entity26",
"@entity1442",
"@entity519",
"@entity521",
"@entity2427",
"@entity694"
] | @entity521 is a common solid @entity5 of childhood and @entity1442 carries a poor prognosis despite intensive multimodality therapy. @entity519 is a common feature of solid @entity5 because of poorly organized @entity5 -induced neovasculature. @entity519 is associated with advanced stage and poor outcome in a range of ... | [
"@entity519"
] |
2099844 | 2099845 | 2099846 | The novel @entity588 inhibitor @entity2427 is more effective in XXXX and is able to reverse @entity519 -induced drug resistance in @entity521 cells.
| multiple_choice | [
"@entity7738",
"@entity588",
"@entity5",
"@entity1836",
"@entity2423",
"@entity1149",
"@entity26",
"@entity1442",
"@entity519",
"@entity521",
"@entity2427",
"@entity694"
] | @entity521 is a common solid @entity5 of childhood and @entity1442 carries a poor prognosis despite intensive multimodality therapy. @entity519 is a common feature of solid @entity5 because of poorly organized @entity5 -induced neovasculature. @entity519 is associated with advanced stage and poor outcome in a range of ... | [
"@entity519"
] |
2099847 | 2099848 | 2099849 | The novel @entity588 inhibitor @entity2427 is more effective in @entity519 and is able to reverse @entity519 -induced drug resistance in XXXX cells.
| multiple_choice | [
"@entity7738",
"@entity588",
"@entity5",
"@entity1836",
"@entity2423",
"@entity1149",
"@entity26",
"@entity1442",
"@entity519",
"@entity521",
"@entity2427",
"@entity694"
] | @entity521 is a common solid @entity5 of childhood and @entity1442 carries a poor prognosis despite intensive multimodality therapy. @entity519 is a common feature of solid @entity5 because of poorly organized @entity5 -induced neovasculature. @entity519 is associated with advanced stage and poor outcome in a range of ... | [
"@entity521"
] |
2099850 | 2099851 | 2099852 | The novel @entity588 inhibitor XXXX is more effective in @entity519 and is able to reverse @entity519 -induced drug resistance in @entity521 cells.
| multiple_choice | [
"@entity7738",
"@entity588",
"@entity5",
"@entity1836",
"@entity2423",
"@entity1149",
"@entity26",
"@entity1442",
"@entity519",
"@entity521",
"@entity2427",
"@entity694"
] | @entity521 is a common solid @entity5 of childhood and @entity1442 carries a poor prognosis despite intensive multimodality therapy. @entity519 is a common feature of solid @entity5 because of poorly organized @entity5 -induced neovasculature. @entity519 is associated with advanced stage and poor outcome in a range of ... | [
"@entity2427"
] |
2099853 | 2099854 | 2099855 | The novel XXXX inhibitor @entity2427 is more effective in @entity519 and is able to reverse @entity519 -induced drug resistance in @entity521 cells.
| multiple_choice | [
"@entity7738",
"@entity588",
"@entity5",
"@entity1836",
"@entity2423",
"@entity1149",
"@entity26",
"@entity1442",
"@entity519",
"@entity521",
"@entity2427",
"@entity694"
] | @entity521 is a common solid @entity5 of childhood and @entity1442 carries a poor prognosis despite intensive multimodality therapy. @entity519 is a common feature of solid @entity5 because of poorly organized @entity5 -induced neovasculature. @entity519 is associated with advanced stage and poor outcome in a range of ... | [
"@entity588"
] |
2099856 | 2099857 | 2099858 | Interactions between dietary fibre, endo-parasites and XXXX bacteria in grower-finisher @entity1707 .
| multiple_choice | [
"@entity1707",
"@entity281",
"@entity18375"
] | Samples of faeces and feed were collected from grower and finisher @entity1707 kept on 25 commercial breeder-finisher units in the West-Midlands region of England. Faecal samples were examined for parasite eggs (Ascaris suis, Trichuris suum and strongylid species) using faecal flotation; and for @entity18375 bacteria u... | [
"@entity18375"
] |
2099859 | 2099860 | 2099861 | Interactions between dietary fibre, endo-parasites and @entity18375 bacteria in grower-finisher XXXX .
| multiple_choice | [
"@entity1707",
"@entity281",
"@entity18375"
] | Samples of faeces and feed were collected from grower and finisher @entity1707 kept on 25 commercial breeder-finisher units in the West-Midlands region of England. Faecal samples were examined for parasite eggs (Ascaris suis, Trichuris suum and strongylid species) using faecal flotation; and for @entity18375 bacteria u... | [
"@entity1707"
] |
2099862 | 2099863 | 2099864 | XXXX and TCR clone: markers of @entity4888 .
| multiple_choice | [
"@entity4888",
"@entity1",
"@entity10793",
"@entity3217",
"@entity20956",
"@entity784"
] | Making a differential diagnosis between @entity4888 and @entity20956 is often difficult at the clinical and histological level. The aim of this study was to explore markers that could help in this process. A total of 88 @entity1 were included in 2 categories: @entity20956 and @entity20956 . A histological examination w... | [
"@entity10793"
] |
2099865 | 2099866 | 2099867 | @entity10793 and TCR clone: markers of XXXX .
| multiple_choice | [
"@entity4888",
"@entity1",
"@entity10793",
"@entity3217",
"@entity20956",
"@entity784"
] | Making a differential diagnosis between @entity4888 and @entity20956 is often difficult at the clinical and histological level. The aim of this study was to explore markers that could help in this process. A total of 88 @entity1 were included in 2 categories: @entity20956 and @entity20956 . A histological examination w... | [
"@entity4888"
] |
2099868 | 2099869 | 2099870 | Absence of XXXX in pediatric adenoid hyperplasia.
| multiple_choice | [
"@entity1",
"@entity5072",
"@entity2348",
"@entity1534"
] | OBJECTIVES: To (1) develop a reverse transcription-polymerase chain reaction assay to determine whether @entity1534 and/or other members of the Helicobacteraceae family are detected in @entity5072 adenoids of @entity1 and (2) critically analyze published polymerase chain reaction methods to ascertain whether false-posi... | [
"@entity1534"
] |
2099871 | 2099872 | 2099873 | Relationship between Leapfrog Safe Practices Survey and outcomes in XXXX .
| multiple_choice | [
"@entity1",
"@entity130",
"@entity580"
] | OBJECTIVE: To examine the association between hospital self-reported compliance with the National Quality Forum @entity1 safety practices and @entity130 outcomes in a nationally representative sample of level I and level II @entity130 centers. DESIGN: Retrospective cohort study using the Nationwide Inpatient Sample. SE... | [
"@entity130"
] |
2099874 | 2099875 | 2099876 | XXXX resistance in group A streptococci.
| multiple_choice | [
"@entity1",
"@entity7646",
"@entity2929",
"@entity4195",
"@entity7187",
"@entity13172"
] | Two hundred and twenty one @entity4195 isolates collected from throat swabs of untreated @entity1 with @entity13172 living in two centres situated in the north of Italy were tested to evaluate their @entity7646 resistance phenotype. Isolates were also typed for T protein and assayed for opacity factor (OF) and protease... | [
"@entity7646"
] |
2099877 | 2099878 | 2099879 | Shoulder MR arthrography of the posterior labrocapsular complex in overhead throwers with pathologic internal impingement and XXXX .
| multiple_choice | [
"@entity717",
"@entity158"
] | PURPOSE: To determine if overhead-throwing athletes with internal @entity158 and @entity717 have thickening of the posterior inferior labrocapsular complex on MR arthrogram images. MATERIALS AND METHODS: This study was approved and a waiver of consent granted by our institutional review board. Twenty-six overhead-throw... | [
"@entity717"
] |
2099880 | 2099881 | 2099882 | Femal, a herbal remedy made from pollen extracts, reduces hot flushes and improves quality of life in menopausal XXXX : a randomized, placebo-controlled, parallel study.
| multiple_choice | [
"@entity1",
"@entity1168",
"@entity0"
] | BACKGROUND: The fact that hormone replacement therapy has been claimed to increase the risk of @entity0 has made it relevant to search for new non-hormonal treatments of menopausal symptoms. OBJECTIVES: This study aimed to evaluate whether Femal, a herbal remedy made from pollen extracts, alleviates the symptoms of the... | [
"@entity1"
] |
2099883 | 2099884 | 2099885 | High Prevalence of XXXX Low Abundance Drug-Resistant Variants in a Treatment-Naive Population in North Rift Kenya.
| multiple_choice | [
"@entity1",
"@entity645",
"@entity68030",
"@entity19898",
"@entity4216",
"@entity702",
"@entity4334",
"@entity3689",
"@entity19899"
] | UNASSIGNED: The advent of antiretroviral treatment (ART) has resulted in a dramatic reduction in AIDS-related morbidity and mortality. However, the emergence and spread of antiretroviral drug resistance (DR) threaten to negatively impact treatment regimens and compromise efforts to control the epidemic. It is recommend... | [
"@entity645"
] |
2099886 | 2099887 | 2099888 | XXXX @entity1 hospital-associated infections: risks and outcomes.
| multiple_choice | [
"@entity1",
"@entity1850",
"@entity580",
"@entity130",
"@entity647"
] | BACKGROUND: @entity130 @entity1 with surgical procedures, @entity647 ( @entity647 ), @entity1850 ( @entity1850 ), and longer exposure to invasive devices may be at increased risk for @entity580 ( @entity580 ). HAIs have been shown to affect outcome measures, but the extent is not well studied. METHODS: An infection con... | [
"@entity130"
] |
2099889 | 2099890 | 2099891 | @entity130 XXXX hospital-associated infections: risks and outcomes.
| multiple_choice | [
"@entity1",
"@entity1850",
"@entity580",
"@entity130",
"@entity647"
] | BACKGROUND: @entity130 @entity1 with surgical procedures, @entity647 ( @entity647 ), @entity1850 ( @entity1850 ), and longer exposure to invasive devices may be at increased risk for @entity580 ( @entity580 ). HAIs have been shown to affect outcome measures, but the extent is not well studied. METHODS: An infection con... | [
"@entity1"
] |
2099892 | 2099893 | 2099894 | Leukocyte Telomere Length in XXXX @entity1 with a Different Rate of Progression.
| multiple_choice | [
"@entity1",
"@entity32",
"@entity1032",
"@entity195",
"@entity12385",
"@entity688"
] | BACKGROUND: Age and short leukocyte telomeres have been associated with a higher risk of @entity195 (AD). @entity32 is involved in AD and it is suggested that anti-inflammatory @entity688 ( @entity688 ) may partly antagonize these processes. OBJECTIVE: The aim is to correlate telomere length (TL) in peripheral blood mo... | [
"@entity195"
] |
2099895 | 2099896 | 2099897 | Leukocyte Telomere Length in @entity195 XXXX with a Different Rate of Progression.
| multiple_choice | [
"@entity1",
"@entity32",
"@entity1032",
"@entity195",
"@entity12385",
"@entity688"
] | BACKGROUND: Age and short leukocyte telomeres have been associated with a higher risk of @entity195 (AD). @entity32 is involved in AD and it is suggested that anti-inflammatory @entity688 ( @entity688 ) may partly antagonize these processes. OBJECTIVE: The aim is to correlate telomere length (TL) in peripheral blood mo... | [
"@entity1"
] |
2099898 | 2099899 | 2099900 | Dissecting susceptibility from exogenous triggers: the model of alopecia areata and associated XXXX .
| multiple_choice | [
"@entity1",
"@entity483",
"@entity32",
"@entity1569",
"@entity310",
"@entity1694",
"@entity4155",
"@entity379",
"@entity272",
"@entity3646",
"@entity405",
"@entity1663"
] | BACKGROUND: @entity1663 ( @entity1663 ) is a T-cell-driven autoimmune disease of the hair follicle and frequently reported to be associated with @entity272 ( @entity272 ) such as @entity483 ( @entity483 ) or @entity1569 . Interestingly, @entity1663 on the one hand and both @entity483 and @entity1569 on the other hand a... | [
"@entity272"
] |
2099901 | 2099902 | 2099903 | Altered terminal Schwann cell morphology precedes denervation in XXXX @entity19 .
| multiple_choice | [
"@entity1",
"@entity24869",
"@entity22997",
"@entity19",
"@entity14405",
"@entity8919",
"@entity19641",
"@entity4681",
"@entity1358",
"@entity182"
] | UNASSIGNED: In @entity19 that express @entity182 mutations found in @entity1 @entity4681 , degeneration begins in the periphery for reasons that remain unknown. At the neuromuscular junction (NMJ), @entity1358 ( @entity1358 ) have an intimate relationship with motor terminals and are believed to help maintain the integ... | [
"@entity182"
] |
2099904 | 2099905 | 2099906 | Altered terminal Schwann cell morphology precedes denervation in @entity182 XXXX .
| multiple_choice | [
"@entity1",
"@entity24869",
"@entity22997",
"@entity19",
"@entity14405",
"@entity8919",
"@entity19641",
"@entity4681",
"@entity1358",
"@entity182"
] | UNASSIGNED: In @entity19 that express @entity182 mutations found in @entity1 @entity4681 , degeneration begins in the periphery for reasons that remain unknown. At the neuromuscular junction (NMJ), @entity1358 ( @entity1358 ) have an intimate relationship with motor terminals and are believed to help maintain the integ... | [
"@entity19"
] |
2099907 | 2099908 | 2099909 | Long term disability and social status change after XXXX .
| multiple_choice | [
"@entity1",
"@entity5011"
] | OBJECTIVE: Even if the majority of @entity1 with @entity5011 ( @entity5011 ) have a favourable functional outcome some residual motor and sensory signs and symptoms may remain. The aim of this study was to evaluate the long-term effect of @entity5011 on daily life,working activities, hobbies and social status and the p... | [
"@entity5011"
] |
2099910 | 2099911 | 2099912 | Newly Designed Upper Lateral Cartilage XXXX for Preventing Depression of the Keystone Area in Large-Nose Septorhinoplasty.
| multiple_choice | [
"@entity1",
"@entity1912",
"@entity30183"
] | Importance: Because large dorsal reduction may weaken the keystone area, later notching of this area should be prevented while reducing large humps during septorhinoplasty. Objective: To determine whether a triangular-shaped @entity1912 of upper lateral cartilages (ULCs) that we designed can prevent secondary deformity... | [
"@entity1912"
] |
2099913 | 2099914 | 2099915 | Management of non-acute XXXX using the over-the-scope clips (OTSCs): a retrospective single-institution experience.
| multiple_choice | [
"@entity1",
"@entity292",
"@entity344",
"@entity6"
] | INTRODUCTION: Advanced endoscopic techniques provide novel therapies for complications historically treated with surgical interventions. Over-the-scope clips (OTSCs) have recently been shown to be effective at endoscopic closure of @entity344 . We hypothesize that by following classic surgical principles of @entity292 ... | [
"@entity344"
] |
2099916 | 2099917 | 2099918 | Non operative management of blunt XXXX : a prospective evaluation of a standardized treatment protocol.
| multiple_choice | [
"@entity1",
"@entity4558",
"@entity3472",
"@entity1317",
"@entity130"
] | PURPOSE: The advantages of the conservative approach for major @entity130 are still debated. This study was designed to evaluate the safety and effectiveness of NOM in the treatment of minor (grade I-II according with the American Association for the Surgery of @entity130 ; AAST) and severe (AAST grade III-V) blunt @en... | [
"@entity130"
] |
2099919 | 2099920 | 2099921 | XXXX scaphoid non-unions exhibit increased osteoclast activity compared to adjacent cancellous bone.
| multiple_choice | [
"@entity1",
"@entity9889",
"@entity8087",
"@entity1841",
"@entity4910",
"@entity5298",
"@entity1550",
"@entity5299",
"@entity2533",
"@entity3064",
"@entity18297"
] | UNASSIGNED: Scaphoid bones have a high prevalence for non-union. Even with adequate treatment, bone regeneration may not occur in certain instances. Although this condition is well described, the molecular pathology of scaphoid non-unions is still poorly defined. In this study, gene expression of osteogenic and angioge... | [
"@entity1"
] |
2099922 | 2099923 | 2099924 | Cognitive course in first-episode XXXX and clinical correlates: A 4year longitudinal study using the MATRICS Consensus Cognitive Battery.
| multiple_choice | [
"@entity73",
"@entity716"
] | UNASSIGNED: While @entity73 are prevalent in first-episode @entity716 , the course of these deficits is not fully understood. Most deficits appear to remain stable, however there is uncertainty regarding the trajectory of specific cognitive domains after illness onset. This study investigates the longitudinal course of... | [
"@entity716"
] |
2099925 | 2099926 | 2099927 | Diffuse XXXX leads to a decrease in unipolar voltage: Validation in a @entity1707 model of premature ventricular contraction-induced @entity296 .
| multiple_choice | [
"@entity1",
"@entity1707",
"@entity296",
"@entity82",
"@entity2634",
"@entity384",
"@entity1540"
] | BACKGROUND: Frequent @entity1540 ( @entity1540 ) may lead to @entity384 . A leftward shift in the unipolar voltage distribution in @entity1 with @entity296 has also been described and attributed to increased @entity82 . OBJECTIVES: We established a @entity1707 model of @entity2634 -induced @entity296 and assessed (1) w... | [
"@entity82"
] |
2099928 | 2099929 | 2099930 | Diffuse @entity82 leads to a decrease in unipolar voltage: Validation in a XXXX model of premature ventricular contraction-induced @entity296 .
| multiple_choice | [
"@entity1",
"@entity1707",
"@entity296",
"@entity82",
"@entity2634",
"@entity384",
"@entity1540"
] | BACKGROUND: Frequent @entity1540 ( @entity1540 ) may lead to @entity384 . A leftward shift in the unipolar voltage distribution in @entity1 with @entity296 has also been described and attributed to increased @entity82 . OBJECTIVES: We established a @entity1707 model of @entity2634 -induced @entity296 and assessed (1) w... | [
"@entity1707"
] |
2099931 | 2099932 | 2099933 | Diffuse @entity82 leads to a decrease in unipolar voltage: Validation in a @entity1707 model of premature ventricular contraction-induced XXXX .
| multiple_choice | [
"@entity1",
"@entity1707",
"@entity296",
"@entity82",
"@entity2634",
"@entity384",
"@entity1540"
] | BACKGROUND: Frequent @entity1540 ( @entity1540 ) may lead to @entity384 . A leftward shift in the unipolar voltage distribution in @entity1 with @entity296 has also been described and attributed to increased @entity82 . OBJECTIVES: We established a @entity1707 model of @entity2634 -induced @entity296 and assessed (1) w... | [
"@entity296"
] |
2099934 | 2099935 | 2099936 | Outcome and quality of life 5 years after XXXX .
| multiple_choice | [
"@entity1",
"@entity158",
"@entity130"
] | BACKGROUND: This study aimed to determine quality of life after injury and identify factors potentially associated with outcome. METHODS: Five years after injury from blunt or penetrating @entity130 , @entity1 received a questionnaire based on the SF-36 Health Survey. RESULTS: Two hundred five @entity1 (83%) replied. M... | [
"@entity130"
] |
2099937 | 2099938 | 2099939 | Etiopathogenesis of XXXX .
| multiple_choice | [
"@entity4128",
"@entity1",
"@entity712",
"@entity944",
"@entity1131",
"@entity8452",
"@entity35969",
"@entity23963",
"@entity1934",
"@entity141",
"@entity943",
"@entity68031",
"@entity19620"
] | @entity4128 ( @entity68031 ) is characterised by progressive fibro-fatty replacement of right ventricular myocardium. Earlier studies described @entity68031 as non-inflammatory, non-coronary disorder associated with @entity943 , @entity712 and @entity944 due to functional exclusion of the right ventricle. Molecular gen... | [
"@entity4128"
] |
2099940 | 2099941 | 2099942 | T-cell-based vaccination for morphological and functional neuroprotection in a XXXX model of chronically elevated intraocular pressure.
| multiple_choice | [
"@entity1",
"@entity68032",
"@entity598",
"@entity726",
"@entity989",
"@entity35"
] | Acute or chronic @entity726 is often associated with an increase in intraocular pressure (IOP). In many @entity1 , however, therapeutic pressure reduction does not halt disease progression. Neuroprotection has been proposed as a complementary therapeutic approach. We previously demonstrated effective T-cell-based neuro... | [
"@entity35"
] |
2099943 | 2099944 | 2099945 | Differential protein expression and oncogenic gene network link XXXX kinase Ephrin B4 receptor to aggressive @entity356 .
| multiple_choice | [
"@entity3557",
"@entity1",
"@entity5344",
"@entity706",
"@entity242",
"@entity5",
"@entity66",
"@entity355",
"@entity2615",
"@entity11",
"@entity25335",
"@entity1778",
"@entity3",
"@entity14",
"@entity354",
"@entity4149",
"@entity21046",
"@entity356"
] | UNASSIGNED: Transmembrane @entity4149 -kinase Ephrin receptors promote @entity5 progression and/or @entity3 of several @entity5 including @entity1778 , @entity706 , @entity11 , malignant @entity2615 , @entity3557 , @entity242 , and @entity5344 . They also drive intestinal stem-cell proliferation and positioning, contro... | [
"@entity4149"
] |
2099946 | 2099947 | 2099948 | Differential protein expression and oncogenic gene network link @entity4149 kinase Ephrin B4 receptor to aggressive XXXX .
| multiple_choice | [
"@entity3557",
"@entity1",
"@entity5344",
"@entity706",
"@entity242",
"@entity5",
"@entity66",
"@entity355",
"@entity2615",
"@entity11",
"@entity25335",
"@entity1778",
"@entity3",
"@entity14",
"@entity354",
"@entity4149",
"@entity21046",
"@entity356"
] | UNASSIGNED: Transmembrane @entity4149 -kinase Ephrin receptors promote @entity5 progression and/or @entity3 of several @entity5 including @entity1778 , @entity706 , @entity11 , malignant @entity2615 , @entity3557 , @entity242 , and @entity5344 . They also drive intestinal stem-cell proliferation and positioning, contro... | [
"@entity356"
] |
2099949 | 2099950 | 2099951 | Examining links between XXXX , reinvestment and walking when talking by older adults during adaptive gait.
| multiple_choice | [
"@entity1",
"@entity73",
"@entity2414",
"@entity148"
] | UNASSIGNED: Falls by older adults often result in reduced quality of life and debilitating fear of further falls. Stopping walking when talking (SWWT) is a significant predictor of future falls by older adults and is thought to reflect age-related increases in attentional demands of walking. We examine whether SWWT is ... | [
"@entity148"
] |
2099952 | 2099953 | 2099954 | Umbilical XXXX : predisposing factors and treatment.
| multiple_choice | [
"@entity1",
"@entity20536",
"@entity2869",
"@entity547"
] | @entity2869 is a common problem of sacrococcygeal region. However, it is also observed in the periumbilical area. There are only a few reports about umbilical @entity2869 in the literature. In this study, 26 @entity1 (24 @entity1 (92 %), 2 @entity1 (8 %) with a mean age of 22 years) with umbilical @entity2869 were incl... | [
"@entity2869"
] |
2099955 | 2099956 | 2099957 | Does long-term passive stretching alter muscle-tendon unit mechanics in @entity1 with XXXX ?
| multiple_choice | [
"@entity1",
"@entity3656",
"@entity73",
"@entity306",
"@entity6475",
"@entity121",
"@entity2693"
] | BACKGROUND: @entity306 causes @entity73 during development and many @entity1 may experience excessive neural and mechanical @entity121 . The clinical assumption is that excessive @entity2693 is thought to be one of the main reasons for functional impairments in @entity306 . As such, passive stretching is widely used to... | [
"@entity306"
] |
2099958 | 2099959 | 2099960 | Does long-term passive stretching alter muscle-tendon unit mechanics in XXXX with @entity306 ?
| multiple_choice | [
"@entity1",
"@entity3656",
"@entity73",
"@entity306",
"@entity6475",
"@entity121",
"@entity2693"
] | BACKGROUND: @entity306 causes @entity73 during development and many @entity1 may experience excessive neural and mechanical @entity121 . The clinical assumption is that excessive @entity2693 is thought to be one of the main reasons for functional impairments in @entity306 . As such, passive stretching is widely used to... | [
"@entity1"
] |
2099961 | 2099962 | 2099963 | EFFECT OF SEASONAL CHANGES ON TESTICULAR MORPHOLOGY AND THE EXPRESSION OF CIRCADIAN CLOCK GENES IN JAPANESE WOOD XXXX (APODEMUS SPECIOSUS).
| multiple_choice | [
"@entity14733",
"@entity37922",
"@entity19",
"@entity2339",
"@entity14734"
] | UNASSIGNED: This study aimed to determine the seasonality of reproduction throughout the year in Japanese wood @entity19 (Apodemus speciosus). The effect of seasonal changes on testicular morphology and the periodic expression of circadian clock genes in the @entity2339 and testes of male individuals was evaluated. We ... | [
"@entity19"
] |
2099964 | 2099965 | 2099966 | [ @entity145 of the middle cranial fossa presented as XXXX ].
| multiple_choice | [
"@entity1",
"@entity3439",
"@entity854",
"@entity1410",
"@entity145",
"@entity531"
] | The aim of the study was to present the authors' own experience and discuss the treatment method of @entity145 of the middle cranial fossa disclosed as @entity3439 . Three cases of male @entity1 operated on because of chronic @entity3439 are presented. Control CT studies after evacuation of @entity1410 revealed @entity... | [
"@entity3439"
] |
2099967 | 2099968 | 2099969 | [ XXXX of the middle cranial fossa presented as @entity3439 ].
| multiple_choice | [
"@entity1",
"@entity3439",
"@entity854",
"@entity1410",
"@entity145",
"@entity531"
] | The aim of the study was to present the authors' own experience and discuss the treatment method of @entity145 of the middle cranial fossa disclosed as @entity3439 . Three cases of male @entity1 operated on because of chronic @entity3439 are presented. Control CT studies after evacuation of @entity1410 revealed @entity... | [
"@entity145"
] |
2099970 | 2099971 | 2099972 | Treatment of @entity5 by photo-induction combined to systemic chemotherapy: Proof of concept on XXXX and feasibility study on porcine chest cavities.
| multiple_choice | [
"@entity4936",
"@entity137",
"@entity242",
"@entity5",
"@entity2",
"@entity900",
"@entity2615",
"@entity35",
"@entity420"
] | BACKGROUND: Low-dose, @entity4936 -mediated photodynamic therapy (photo-induction) was shown to selectively enhance @entity5 vessel transport causing increased uptake of systemically administered chemotherapy in various @entity5 types grown on rodent lungs. The present experiments explore the efficacy of photo-induced... | [
"@entity2"
] |
2099973 | 2099974 | 2099975 | Treatment of XXXX by photo-induction combined to systemic chemotherapy: Proof of concept on @entity2 and feasibility study on porcine chest cavities.
| multiple_choice | [
"@entity4936",
"@entity137",
"@entity242",
"@entity5",
"@entity2",
"@entity900",
"@entity2615",
"@entity35",
"@entity420"
] | BACKGROUND: Low-dose, @entity4936 -mediated photodynamic therapy (photo-induction) was shown to selectively enhance @entity5 vessel transport causing increased uptake of systemically administered chemotherapy in various @entity5 types grown on rodent lungs. The present experiments explore the efficacy of photo-induced... | [
"@entity5"
] |
2099976 | 2099977 | 2099978 | Supracondylar skeletal traction and open interlocking nailing for neglected XXXX of the shaft of femur - Retrospective study.
| multiple_choice | [
"@entity174",
"@entity1",
"@entity531",
"@entity130"
] | BACKGROUND: Neglected @entity130 is a common problem faced by Orthopaedic surgeons practicing in developing countries. Nothing much in English literature is available regarding the practical difficulties and guidelines for treating neglected @entity130 of long bones. METHODS: In our institution from November 2003 to Oc... | [
"@entity174"
] |
2099979 | 2099980 | 2099981 | A XXXX - @entity584 Feed-Forward Topology Underlies @entity7514 Resiliency in @entity1722 -Amplified Cancers.
| multiple_choice | [
"@entity7514",
"@entity5",
"@entity584",
"@entity29855",
"@entity1722"
] | The requisite role of @entity7514 in @entity1722 -amplified @entity5 is beyond what would be expected as a dimerization partner or effector substrate and it exhibits a substantial degree of resiliency that mitigates the effects of @entity1722 -inhibitor therapies. To better understand the roots of this resiliency, we c... | [
"@entity29855"
] |
2099982 | 2099983 | 2099984 | A @entity29855 - @entity584 Feed-Forward Topology Underlies XXXX Resiliency in @entity1722 -Amplified Cancers.
| multiple_choice | [
"@entity7514",
"@entity5",
"@entity584",
"@entity29855",
"@entity1722"
] | The requisite role of @entity7514 in @entity1722 -amplified @entity5 is beyond what would be expected as a dimerization partner or effector substrate and it exhibits a substantial degree of resiliency that mitigates the effects of @entity1722 -inhibitor therapies. To better understand the roots of this resiliency, we c... | [
"@entity7514"
] |
2099985 | 2099986 | 2099987 | A @entity29855 - @entity584 Feed-Forward Topology Underlies @entity7514 Resiliency in XXXX -Amplified Cancers.
| multiple_choice | [
"@entity7514",
"@entity5",
"@entity584",
"@entity29855",
"@entity1722"
] | The requisite role of @entity7514 in @entity1722 -amplified @entity5 is beyond what would be expected as a dimerization partner or effector substrate and it exhibits a substantial degree of resiliency that mitigates the effects of @entity1722 -inhibitor therapies. To better understand the roots of this resiliency, we c... | [
"@entity1722"
] |
2099988 | 2099989 | 2099990 | A @entity29855 - XXXX Feed-Forward Topology Underlies @entity7514 Resiliency in @entity1722 -Amplified Cancers.
| multiple_choice | [
"@entity7514",
"@entity5",
"@entity584",
"@entity29855",
"@entity1722"
] | The requisite role of @entity7514 in @entity1722 -amplified @entity5 is beyond what would be expected as a dimerization partner or effector substrate and it exhibits a substantial degree of resiliency that mitigates the effects of @entity1722 -inhibitor therapies. To better understand the roots of this resiliency, we c... | [
"@entity584"
] |
2099991 | 2099992 | 2099993 | [Acute transverse XXXX : inflammatory or ischemic?].
| multiple_choice | [
"@entity5697",
"@entity17",
"@entity1494",
"@entity63",
"@entity75",
"@entity1652",
"@entity602",
"@entity262",
"@entity1746",
"@entity51",
"@entity6128",
"@entity1745",
"@entity1188",
"@entity2759",
"@entity1651",
"@entity15",
"@entity4685",
"@entity10492"
] | The rapid development of @entity1746 or @entity10492 combined with a bilateral @entity51 that has a clearly defined rostral border and @entity1494 are the principal features of @entity5697 . Acute partial transverse @entity602 is far much more frequent: its symptoms are asymmetric, sometimes unilateral, and @entity51 m... | [
"@entity602"
] |
2099994 | 2099995 | 2099996 | Multimodality therapy for locally advanced XXXX : A propensity score-matched cohort study from the European Society of Thoracic Surgeons Database.
| multiple_choice | [
"@entity1",
"@entity1803",
"@entity704",
"@entity5",
"@entity2",
"@entity1753"
] | OBJECTIVE: This study investigated the prognostic impact of multimodality therapies in locally advanced @entity704 . METHODS: From January 1990 to January 2010, clinicopathological, surgical, and oncological features were retrospectively reviewed in a cohort of 370 Masaoka-Koga @entity5 (World Health Organization class... | [
"@entity704"
] |
2099997 | 2099998 | 2099999 | A Bruch's membrane substitute fabricated from silk fibroin supports the function of XXXX pigment epithelial cells in vitro.
| multiple_choice | [
"@entity1",
"@entity11178",
"@entity3529",
"@entity4024",
"@entity7",
"@entity31923",
"@entity5995",
"@entity1020",
"@entity32704"
] | UNASSIGNED: Silk fibroin provides a promising biomaterial for ocular tissue reconstruction, including the damaged outer blood- @entity5995 barrier of @entity1 afflicted with @entity1020 ( @entity1020 ). The aim of the present study was to evaluate the function of @entity5995 pigment epithelial (RPE) cells in vitro, whe... | [
"@entity5995"
] |
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