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Longer duration of neoadjuvant (NA) imatinib (IM) used for locally advanced (LA) gastrointestinal stromal tumours (GIST) is not based on biology of the tumour reflected by kit mutation analysis. LA or locally recurrent (LR) GIST treated with NA IM from May 2008 to March 2015 from a prospective database were included in...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To analyze, retrospectively, the patterns and behavior of metastatic lesions in prostate cancer patients treated with external beam radiotherapy and to investigate whether patients with<or =5 lesions had an improved outcome relative to patients with>5 lesions. The treatment and outcome of 369 eligible patients with Sta...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The purpose of this paper is to evaluate the efficacy of ultrasonographic screening for primary hepatocellular carcinoma. A total of 680 eligible cases were classified into three groups (surveillance, opportunistic, and symptomatic groups) according to their initial exposure. We used survival time, tumor morphology, an...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Effective musical communication requires conveyance of the intended message in a manner perceptible to the receiver. Communication disorders that impair transmitting or decoding of structural features of music (e.g., pitch, timbre) and/or symbolic representation may result in atypical musical communication, which can h...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Up to 30 % of patients who have undergone laparoscopic sleeve gastrectomy require revision surgery for inadequate weight loss, weight regain, and/or the development of severe upper gastrointestinal symptoms. The aim of this retrospective study was to evaluate the safety and efficacy of laparoscopic fundectomy (LF) in c...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Microbial contamination can be a marker for faulty process and is assumed to play an important role in the collection of hematopoietic progenitor cell (HPC) and infusion procedure. We aimed to determine the microbial contamination rates and evaluate the success of hematopoietic cell transplantation (HCT) in patients wh...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Female citizens of Sami (the indigenous people of Norway) municipalities in northern Norway have a low risk of breast cancer. The objective of this study was to describe the attendance rate and outcome of the Norwegian Breast Cancer Screening Program (NBCSP) in the Sami-speaking municipalities and a control group. A re...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Although there is evidence for the influential role of transformational leadership on health outcomes, researchers have used either attitude outcomes (e.g. job satisfaction) or softer health measures, such as general well-being. Specific measures of well-being such as sleep quality have not been used, despite its assoc...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Angiotensin-converting enzyme inhibitors (ACE-I) are considered safe, but they are associated with characteristic side effects, namely cough and angioedema, usually requiring discontinuation. We perceived that referrals for these side effects have become more and more frequent; therefore, we evaluated the degree of kno...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Epidemiologic studies have suggested that hypertriglyceridemia and insulin resistance are related to the development of colon cancer. Nuclear peroxisome proliferator-activated receptors (PPAR), which play a central role in lipid and glucose metabolism, had been hypothesized as being involved in colon cancerogenesis. In...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Research on stroke survivors' driving safety has typically used either self-reports or government records, but the extent to which the 2 may differ is not known. We compared government records and self-reports of motor vehicle collisions and driving convictions in a sample of stroke survivors. The 56 participants were ...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
DNA was collected for genotyping from 73 term newborns suffering from TTN and 55 healthy controls from a Caucasian cohort. TTN infants were more likely to be male (70% vs. 49%; p<0.05), had a lower mean birthweight (3120 +/- 450 vs. 3396 +/- 504 g; p<0.001) and gestational age (GA) (38.4 +/- 1.2 vs. 39.4 +/- 1.3 weeks;...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Hypoglycaemia caused by glucose-lowering therapy has been linked to cardiovascular (CV) events. The ORIGIN trial provides an opportunity to further assess this relationship. A total of 12 537 participants with dysglycaemia and high CV-risk were randomized to basal insulin glargine titrated to a fasting glucose of ≤ 5.3...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Breast cancer is the most common malignancy afflicting women, and the most common cancer overall in Jordan. A woman's decision to go for screening is influenced by her social support network. This study aims to explore Jordanian men's individual and contextual perspectives on women's breast cancer and their own role in...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Ischemia-reperfusion (IR) injury remains a major cause of early morbidity and mortality after lung transplantation with poorly documented extrapulmonary repercussions. To determine the hemodynamic effect due to lung IR injury, we performed a quantitative coronary blood-flow analysis in a swine model of in situ lung isc...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
It is postulated that some aspects of methotrexate toxicity may be related to its action as an anti-folate. Folic acid (FA) is often given as an adjunct to methotrexate therapy, but there is no conclusive proof that it decreases the toxicity of methotrexate and there is a theoretical risk that it may decrease the effic...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
From 2000 to 2007, 344 patients underwent pancreatoduodenectomy for PA. Fifty-three patients (elevated group) had preoperatively elevated serum CA 19-9 levels (>400 IU/ml) after resolution of obstructive jaundice. Of these, 27 patients had high levels (400-899 IU/ml (HL)) and 26 patients had very high levels>or=900 IU/...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
There is increasing pressure on mental health providers to reduce the duration of treatments, while retaining level of quality and effectiveness. The risk is that the population is underserved and therefore needs new treatment episodes. The primary aim of this study was to investigate whether duration of treatment and ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The correlation between radiographic transition zone on contrast enema in Hirschsprung's disease and the total length of aganglionosis is known to be inaccurate. The aim of our study was to analyse this correlation more precisely to improve preoperative planning of the corrective surgery. From 1998 to 2009, 79 patients...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Recent suicide bombings pose the novel problem for Trauma Centers of the massive simultaneous arrival of many gravely wounded patients. We report the experience of the French-German Military Trauma Group, a Level 2 Trauma Center, in Afghanistan during the wave of suicide bombings in February 2007. Fourteen casualties w...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Demonstrate that the rabbit may be used in the training of surgery, in addition to present its perioperative care. Thirty two animals, with age and weight, respectively, from 3 to 5.5 months old and 3000 to 4200 grams, were undergone different periods of pre-operative fasting, exclusive intramuscular anesthesia (ketami...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Atrial fibrillation, which occurs in 12% of all major foregut surgeries, can prolong hospital stay and increase morbidity. Minimally invasive techniques in foregut surgery have been suggested to cause less tissue trauma. We examined the factors associated with new-onset atrial fibrillation after foregut surgery at our ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Racial differences in asthma care are not fully explained by socioeconomic status, care access, and insurance status. Appropriate care requires accurate physician estimates of severity. It is unknown if accuracy of physician estimates differs between black and white patients, and how this relates to asthma care dispari...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The aim of this prognostic factor analysis was to investigate if a patient's self-reported health-related quality of life (HRQOL) provided independent prognostic information for survival in non-small cell lung cancer (NSCLC) patients. Pretreatment HRQOL was measured in 391 advanced NSCLC patients using the EORTC QLQ-C3...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
A prospective randomized clinical study. To determine whether shaving the incision site before spinal surgery causes postsurgical infection. Spine surgeons usually shave the skin of the incision site immediately before surgery is performed. However, evidence from some surgical series suggests that presurgical shaving m...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
The rate of aortic aneurysm rupture correlates with the aneurysm's diameter, and a higher rate of rupture is observed in patients with larger aneurysms. According to the literature, contradictory results concerning the relationship between atmospheric pressure and aneurysm size have been reported.AIM: In this paper, we...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Evidence suggests substantial comorbidity between symptoms of somatization and depression in clinical as well as nonclinical populations. However, as most existing research has been retrospective or cross-sectional in design, very little is known about the specific nature of this relationship. In particular, it is uncl...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
The precise correction of refractive error is especially important in young adults. It is unclear whether cycloplegic refraction is necessary in this age group. The purpose of this study was to compare the non-cycloplegic and cycloplegic spherical equivalent (SE) refractive error measured in young adults. This was a pr...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
To determine under what conditions lay people and health professionals find it acceptable for a physician to breach confidentiality to protect the wife of a patient with a sexually transmitted disease (STD). In a study in France, breaching confidentiality in 48 scenarios were accepted by 144 lay people, 10 psychologist...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
To evaluate the efficacy of extracorporeal shock wave lithotripsy (SWL) on lower calyceal calculi in relation to the renal anatomical factors and determine which of these factors can be used to select patients who will benefit from SWL. We analyzed retrospectively 78 patients with single radiopaque lower calyceal stone...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Although record linkage of routinely collected health datasets is a valuable research resource, most datasets are established for administrative purposes and not for health outcomes research. In order for meaningful results to be extrapolated to specific populations, the limitations of the data and linkage methodology ...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Combining various antiretroviral agents into one single dosage form has been a strategy to reduce pill burden and enhance medication adherence among human immunodeficiency virus /AIDS (HIV/AIDS) patients. This is a cost-utility study from a health care system's perspective comparing coformulated fixed dose (FXD) strate...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
This paper investigates the impact of geographic scale (census tract, zip code, and county) on the detection of disparities in breast cancer mortality among three ethnic groups in Texas (period 1995-2005). Racial disparities were quantified using both relative (RR) and absolute (RD) statistics that account for the popu...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
It is uncertain whether the inverse equity hypothesis-the idea that new health interventions are initially primarily accessed by the rich, but that inequalities narrow with diffusion to the poor-holds true for cancer screening in low and middle income countries (LMICs).This study examines the relationship between overa...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Myocardial damage that is associated with percutaneous coronary intervention (PCI) partially affects the results of the procedure, and is related to medium-term cardiovascular death. Remote postischemic conditioning might reduce the myocardial lesions that are associated with PCI, but perhaps less so in diabetics. The ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Injury severity score (ISS), Glasgow coma score (GCS), and revised trauma score (RTS) are the most frequently used methods to evaluate the severity of injury in blunt trauma patients. ISS is too complicated to assess easily and GCS and RTS are easy to assess but somewhat subjective. White blood cell count (WBC) is an e...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Disorders of consciousness (DOC) diagnosis relies on the presence or absence of purposeful motor responsiveness, which characterizes the minimally conscious state (MCS) and the unresponsive wakefulness syndrome (UWS), respectively. Functional neuroimaging studies have raised the question of possible residual conscious ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Aromatase inhibitors (AIs) are an effective treatment for postmenopausal women with hormone receptor-positive breast cancer. However, patients receiving AIs report a higher incidence of musculoskeletal symptoms and bone fractures; the mechanism and risk factors for this correlation are not well studied. The aim of this...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To determine current practice and to assess the value of routine follow-up procedures for endometrial cancer surveillance. To discuss whether such procedures are feasible and effective to identify asymptomatic recurrences and describe the pattern of relapse detected by procedures. The records of 282 consecutive women w...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Despite surgical refinements, perioperative use of tracheobronchoscopy (TBS) as part of surgical approach to esophageal atresia (EA) is still controversial. The purpose of this study was to evaluate the influence of preoperative TBS in newborns with EA in preventing complications and improving diagnosis and surgical tr...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To clarify whether horizontal canal ocular reflex is influenced by otolith organs input. The subjects were seven healthy humans. The right ear was stimulated using ice-water. Each subject was kept in a left-ear-down position for 20 s and then repositioned to a prone position, a right-ear-down position and a supine posi...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To critically assess the evidence that appendiceal perforation is a risk factor for subsequent tubal infertility or ectopic pregnancy. Epidemiologic studies investigating the relationship between appendectomy and infertility or ectopic pregnancy were identified by searching the MEDLINE database from 1966 to 1997. Appro...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Nd:YAG laser-induced thermo therapy (LITT) of rat brains is associated with blood-brain barrier (BBB) permeability changes. We address the question of whether LITT-induced locoregional disruption of the BBB could possibly allow a locoregional passage of chemotherapeutic agents into brain tissue to treat malignant gliom...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To compare the effect of student examiners (SE) to that of faculty examiners (FE) on examinee performance in an OSCE as well as on post-assessment evaluation in the area of emergency medicine management. An OSCE test-format (seven stations: Advanced Cardiac Life Support (ACLS), Basic Life Support (BLS), Trauma-Manageme...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Unicompartmental replacement can be an alternative to tibial osteotomy in younger, active patients with unicompartmental knee disease. In unicompartmental replacement, the other compartments and knee ligaments are largely untouched. Therefore, it was hypothesized that the knee kinematics after unicompartmental replacem...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
There are 71 previously untreated patients with cytological or histological evidence of primary lung cancer who were admitted to the oncology department between November 2013 and August 2014. Forty-five healthy individuals with age, sex and BMI matching the lung cancer patients, were recruited to take part in the study...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The most common primary brain tumors in children and adults are of astrocytic origin. Classic histologic grading schemes for astrocytomas have included evaluating the presence or absence of nuclear abnormalities, mitoses, vascular endothelial proliferation, and tumor necrosis. We evaluated the vascular pattern of 17 as...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Governments are urged to determine methods to control the use of medical resources and curb the rise of healthcare costs. The question is, do health behaviors have an impact on the use of medical resources? This study aims to identify and understand the difference in the number of outpatient visits and health examinati...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
First, to establish whether a deprivation gradient in all-cause mortality exists for all ethnic groups within New Zealand; second, if such gradients do exist, whether their absolute slopes are the same; and third, if such gradients exist, what impact the unequal deprivation distributions of the different ethnic groups ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To investigate if fetal gender (1) affects the risk of having an emergency department (ED) visit for asthma; and (2) is associated with adverse pregnancy outcomes among women who had at least one visit to the ED for asthma during pregnancy. We linked two provincial administrative databases containing records on in-pati...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
This study sought to evaluate mutations in genes encoding the slow component of the cardiac delayed rectifier K+ current (I(Ks)) channel in familial atrial fibrillation (AF). Although AF can have a genetic etiology, links between inherited gene defects and acquired factors such as atrial stretch have not been explored....
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To determine whether the host immune response to gonorrhoea provides limited serovar specific protection from reinfection. 508 episodes of gonorrhoea diagnosed at a city centre genitourinary medicine clinic including 22 patients with multiple infections over a 4 year period. Patients with recurrent gonococcal infection...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The purpose of this study is to determine if baseline antral follicle assessment may serve as additional information in predicting in vitro fertilization outcome. Prospective, descriptive preliminary study of in vitro fertilization outcome. From July 1998 to July 1999, 224 patients underwent antral follicle assessment ...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Weight scales as height squared, which is an observation that forms the basis of body mass index (weight/height(2)). If, and how, circumferences, including waist circumference (WC) and hip circumference (HC), scale to height remains unclear, but this is an important consideration when developing normative ranges or app...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
We explored whether QT corrected dispersion (QTcD) can identify left ventricular hypertrophy (LVH) in hypertensives. We enrolled 100 hypertensive patients (study group) and 30 normotensive subjects (control group). Echocardiography was performed to measure left ventricular mass and left ventricular mass index. Electroc...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Traumatic aortic injury (TAI) is a rare but life-threatening type of injury. We investigate whether the anatomy of the aortic arch influences the severity of aortic injury. This is a retrospective study of twenty-two cases treated with TEVAR for TAI in our department from 2009 to 2014. Aortic injury was assessed in acc...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
This study aims to evaluate local failure patterns in node negative breast cancer patients treated with post-mastectomy radiotherapy including internal mammary chain only. Retrospective analysis of 92 internal or central-breast node-negative tumours with mastectomy and external irradiation of the internal mammary chain...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
This study aimed to evaluate the utility of risk stratification of gynecologic oncology patients with neutropenic fever (NF). A retrospective chart review of gynecologic cancer patients admitted with NF from 2007 to 2011 was performed, wherein demographic, oncologic, and NF characteristics (hospitalization length, comp...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Cyclical pamidronate therapy in a 2-year-old child with skeletal fragility resulted in remodelling of vertebral fractures and improvement in bone mineral density (BMD) at distal radial and spinal sites. The BMD at both sites decreased precipitously within 24 months of stopping treatment, raising the question as to whet...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
To determine whether there are differences between blood pressure (BP) measured by the nurse (NBP), BP measured by the physician (PBP) and self-measured BP in treated hypertensive patients and, if found, to evaluate their clinical importance. An observational study is carried out with hypertensive patients recruited fr...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Hip fracture in geriatric patients has a substantial economic impact and represents a major cause of morbidity and mortality in this population. At our institution, a regional anesthesia program was instituted for patients undergoing surgery for hip fracture. This retrospective cohort review examines the effects of reg...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To compare the probability of prenatal diagnosis (PND) and termination of pregnancy for fetal anomaly (TOPFA) between fetuses conceived by assisted reproductive techniques (ART) and spontaneously-conceived fetuses with congenital heart defects (CHD). Population-based observational study. Paris and surrounding suburbs. ...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Earlier studies have demonstrated low peak oxygen uptake ((.)Vo(2)peak) in children with spina bifida. Low peak heart rate and low peak respiratory exchange ratio in these studies raised questions regarding the true maximal character of (.)Vo(2)peak values obtained with treadmill testing. The aim of this study was to d...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Patients living in rural areas may be at a disadvantage in accessing tertiary health care.AIM: To test the hypothesis that very premature infants born to mothers residing in rural areas have poorer outcomes than those residing in urban areas in the state of New South Wales (NSW) and the Australian Capital Territory (AC...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To compare the primary stability of miniscrews inserted into bone blocks of different bone mineral densities (BMDs) with and without cortical bone, and investigate whether some trabecular properties could influence primary stability. Fifty-two bone blocks were extracted from fresh bovine pelvic bone. Four groups were c...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Ablation of persistent atrial fibrillation (AF) may require adjunctive methods of substrate modification. Both ablation-targeting complex fractionated atrial electrograms (CFAEs) recorded during AF and fractionated electrograms recorded during sinus rhythm (sinus rhythm fractionation [SRF]) have been described. However...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The present study aims to compare strength, healing, and operation time of experimental intestinal anastomoses performed by polyglactin 910 (Vicryl; Ethicon, Edinburgh, United Kingdom) sutures with ethyl-2-cyanoacrylate glue (Pattex; Henkel, Dusseldorf, Germany). Ninety-six Sprague-Dawley rats were divided into 2 (grou...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
This study aims to study femoral tunnel lengths drilled with a flexible reamer and the distance to important lateral structures obtained by flexing the knee at various angles and by drilling the guide pins arthroscopically to resemble clinical practice. The purpose of this cadaveric study was twofold: 1. to determine w...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Clinically positive axillary nodes are widely considered a contraindication to sentinel lymph node (SLN) biopsy in breast cancer, yet no data support this mandate. In fact, data from the era of axillary lymph node dissection (ALND) suggest that clinical examination of the axilla is falsely positive in as many as 30% of...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The "July effect" refers to the phenomenon of adverse impacts on patient care arising from the changeover in medical staff that takes place during this month at academic medical centres in North America. There has been some evidence supporting the presence of the July effect, including data from surgical specialties. U...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To assess quality of storage of vaccines in the community. Questionnaire survey of general practices and child health clinics, and monitoring of storage temperatures of selected refrigerators. Central Manchester and Bradford health districts. 45 general practices and five child health clinics, of which 40 (80%) respond...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Little is known about whether a routinely inserted endoscopic nasobiliary drainage (ENBD) tube improves the clinical course in patients with choledocholithiasis-induced acute cholangitis after clearance of choledocholithiasis. The aim of this study was to investigate the need for ENBD on the clinical outcomes of patien...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
As part of a prospective study on quality of life in newly diagnosed lung cancer patients an investigation was carried out to examine whether there were differences among patients' quality of life scores and their socioeconomic status. Quality of life was measured at two points in time (baseline and three months after ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Community-based medical education is growing to meet the increased demand for quality clinical education in expanded settings, and its sustainability relies on patient participation. This study investigated patients' views on being used as an educational resource for teaching medical students. Questionnaire-based surve...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
We evaluated the differences between percutaneous ethanol injection with and without aspiration of ethanol-mixed fluid for treatment of benign cystic thyroid nodules. We examined 60 patients with benign cystic thyroid nodules confirmed by fine-needle aspiration biopsy and divided them into 2 groups according to nonaspi...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The levels of bone formation and resorption can be assessed at the tissue level by bone histomorphometry on transiliac bone biopsies. Systemic biochemical markers of bone turnover reflect the overall bone formation and resorption at the level of the entire skeleton but cannot discriminate the different skeletal compart...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
The prevalence of retinal haemorrhages after convulsions is not well established. As these haemorrhages are considered characteristic of child abuse, we investigated their occurrence after convulsive episodes to see whether the finding of haemorrhage should prompt further investigation. Prospective study of 153 childre...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Several studies have shown associations between hyperglycemia and risk of cardiovascular disease (CVD) and mortality, yet glucose-lowering treatment does little to mitigate this risk. We examined whether associations between hyperglycemia and CVD risk were explained by underlying insulin resistance. In 60 middle-aged i...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Cholecystectomy for GB polyps that are larger than 10 mm is generally recommended because of the high probability of neoplasm. In contrast, a follow-up strategy is preferred for GB polyps smaller than 10 mm. However, there are no treatment guidelines for polyps that grow in size during the follow-up period.STUDY: We re...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Uterus-specific synthetic Prostaglandin analogues (gemeprost, sulproston etc.) have been widely employed for termination of pregnancy in the second trimester. Since paracervical anaesthesia may be useful during this procedure, we investigated in this prospective randomised study its impact on the clinical course of abo...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Laparoscopic sleeve gastrectomy (LSG) is currently being performed with increasing frequency worldwide. It offers an excellent weight loss and resolution of comorbidities in the short term with a very low incidence of complications. However, the ever present risk of a staple line leak is still a major concern. Since 20...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Irregular bleeding affects many users of combined menopausal hormone therapy (HT) and commonly leads to invasive and expensive investigations to exclude underlying malignancy. In most cases no abnormality is found. The main objective of this study was to explore the role of uterine natural killer (uNK) cells and their ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Mechanically ventilated patients experience profound stress. Interventions are needed to ameliorate stress that does not cause adverse effects. The purpose of this study was to explore the influence of music on stress in a sample of patients over the duration of ventilatory support.RESEARCH METHODOLOGY/ Randomised cont...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To explore the impact of delivery mode on women's postpartum quality of life in rural China and probe factors influencing postnatal quality of life. Childbirth significantly affects puerpera's physical, psychological and social domains of quality of life. Under the circumstance of increasing high caesarean section rate...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
We sought to determine the feasibility and assess the clinical outcomes associated with an early extubation strategy for all children undergoing congenital heart surgery, including neonates (age,<30 days). We performed a linked database analysis of all patients undergoing congenital heart surgery from July 1, 2010 to D...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Prior literature identified the use of Performance Measurement Systems (PMS) as crucial in addressing improved processes of care. Moreover, a strategic use of PMS has been found to enhance quality, compared to non-strategic use, although a clear understanding of this linkage is still to be achieved. This paper deals wi...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Reliable longitudinal data of patients with functional somatic symptoms in general practice are lacking. To identify distinctive features in patients with chronic functional somatic symptoms, and to determine whether these symptoms support the hypothesis of the existence of specific somatic syndromes. Observational stu...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Examine whether patients with prostate cancer choose the more aggressive of two radiotherapeutic options, whether this choice is reasoned, and what the determinants of the choice are. One hundred fifty patients with primary prostate cancer (T(1-3)N(0)M(0)) were informed by means of a decision aid of two treatment optio...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To determine whether successful completion of the Perinatal Education Programme (PEP) improves obstetric practice. The three midwife obstetric units (MOUs) in a health district of Mpumalanga were included in the study. Two MOUs enrolled in the PEP and the third did not. A 'before-and-after' study design was used to ass...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The specific aim of this investigation was to evaluate the proficiency of health care providers and patients in the proper use of metered-dose inhalers. Health care providers, which include house staff, nurses, and respiratory care practitioners who provide care to patients with asthma in the primary general medicine c...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Medicare beneficiaries who have chronic conditions are responsible for a disproportionate share of Medicare fee-for-service expenditures. The objective of this study was to analyze the change in the health of Medicare beneficiaries enrolled in Part A (hospital insurance) between 2008 and 2010 by comparing the prevalenc...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Urine samples were examined by wet smear microscopy, incubated in 5% CO(2) for 1-2 days, and species-specific real-time polymerase chain reaction (PCR) for A. schaalii was performed. In 5 of the 29 screened urines, A. schaalii was found only by real-time PCR in quantities equivalent to ≥ 10(4) -10(5) CFU/mL. In additio...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
To investigate the effect of bracket-ligature combination on the amount of orthodontic space closure over three months. Randomized clinical trial with three parallel groups. A hospital orthodontic department (Chesterfield Royal Hospital, UK). Forty-five patients requiring upper first premolar extractions. Informed cons...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Spasticity and loss of function in an affected arm are common after stroke. Although botulinum toxin is used to reduce spasticity, its functional benefits are less easily demonstrated. This paper reports an exploratory meta-analysis to investigate the relationship between reduced arm spasticity and improved arm functio...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Vaginal intraepithelial neoplasia is a little known disease which could be related to risk factors different from simple HPV infections. To ascertain wheter vaginal lesions have a natural history similar to cervical lesions.MATERIALS & A retrospective study to identify patients with vaginal lesions and synchronous cerv...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
There has never been a nationally representative survey of medical students' personal health-related practices, although they are inherently of interest and may affect patient-counseling practices. This study evaluated the health practices and the vaccination status of first year residents working at the academic hospi...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To study the efficiency and safety of holmium:YAG laser lithotripsy for ureteral stones. A series of 188 patients with 208 ureteral stones were treated with semirigid ureteroscopy and holmium:YAG laser lithotripsy from January 2003 to December 2005. Of the stones, 116 were lower ureteral, 37 middle ureteral, and 55 upp...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To assess the acceptability to patients of the use of patients' first names by doctors and doctors' first names by patients in general practice. An administered questionnaire survey. 5 General practices in Lothian. 475 Patients consulting 30 general practitioners. Response by patients to questionnaire on attitude to us...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The National Institutes of Health Stroke Scale (NIHSS) is a valid, reproducible scale that measures neurological deficit. Of 42 possible points, 7 points are directly related to measurement of language compared with only 2 points related to neglect. We examined the placebo arm of the NINDS t-PA stroke trial to test the...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The brain-dead donor supply has become one of the criteria limiting the performance of heart transplantation. Conventional screening criteria are too limiting and exclude suitable heart donors. Echocardiography is now widely available and is a reliable tool to assess left ventricular dysfunction in brain-dead donors. Y...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A