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The purpose of this study was to investigate the outcomes that are associated with pregnancy and treated hypothyroidism. This was a retrospective cohort study of all women who received prenatal care and were delivered at the University of California, San Francisco, between 1989 and 2001. All patients with hypothyroidis...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To provide equality of cancer care to rural patients, Townsville Cancer Centre administers intensive chemotherapy regimens to rural patients with node-positive breast and metastatic colorectal cancers at the same doses as urban patients. Side-effects were usually managed by rural general practitioners locally.AIM: The ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To compare atropine with placebo as an adjunct to ketamine sedation in children undergoing minor painful procedures. Outcome measures included hypersalivation, side effect profile, parental/patient satisfaction, and procedural success rate. Children aged between 1 and 16 years of age requiring ketamine procedural sedat...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To determine the cost of 46 commonly used investigations and therapies and to assess British Columbia family doctors' awareness of these costs. Mailed survey asking about costs of 23 investigations and 23 therapies relevant to family practice. A random sample of 600 doctors was asked to report their awareness of costs ...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The aim of our study was to determine the effect of sex on the outcome of laparoscopic cholecystectomy in terms of operative time, conversion to open cholecystectomy, postoperative complications and mean hospital stay. In this retrospective observational study, we analyzed the medical records of 2061 patients who under...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The aim of this study was to assess the diagnostic value of articular sounds, standardized clinical examination, and standardized articular ultrasound in the detection of internal derangements of the temporomandibular joint. Forty patients and 20 asymptomatic volunteers underwent a standardized interview, physical exam...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To determine if composite measures based on process indicators are consistent with short-term outcome indicators in surgical colorectal cancer care. Longitudinal analysis of consistency between composite measures based on process indicators and outcome indicators for 85 Dutch hospitals. The Dutch Surgical Colorectal Au...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Laparoscopic techniques can be used to treat patients whose antireflux surgery has failed. Case series. Two academic medical centers. Forty-six consecutive patients, of whom 21 were male and 25 were female (mean age, 55.6 years; range, 15-80 years). Previous antireflux procedures were laparoscopic (21 patients), laparo...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The primary objective of the study was to determine emergency medical services (EMS) professionals' opinions regarding participation in disease and injury prevention programs. A secondary objective was to determine the proportion of EMS professionals who had participated in disease prevention programs. As part of the N...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Implant-related infections represent one of the most severe complications in orthopaedics. A fast-resorbable, antibacterial-loaded hydrogel may reduce or prevent bacterial colonization and biofilm formation of implanted biomaterials.QUESTIONS/ We asked: (1) Is a fast-resorbable hydrogel able to deliver antibacterial co...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
In familial adenomatous polyposis (FAP), correlations between site of mutation in the adenomatous polyposis coli (APC) gene and severity of colonic polyposis or extracolonic manifestations are well known. While mutation analysis is important for predictive diagnosis in persons at risk, its relevance for clinical manage...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Endometrial polyp is a common cause of abnormal uterine bleeding, but the etiology and pathogenesis remain unclear. Vascular endothelial growth factor (VEGF) is angiogenic, related to thick walled vessels and transforming growth factor-beta1 (TGF-β1) is related to fibrotic tissue, which are characteristics of endometri...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
A multicentre, retrospective study was conducted of patients with rectal cancer threatening or affecting the prostatic plane, but not the bladder, judged by magnetic resonance imaging (MRI). The use of preoperative chemoradiotherapy and the type of urologic resection were correlated with the status of the pathological ...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
To study whether exercise during pregnancy reduces the risk of postnatal depression. Randomized controlled trial. Trondheim and Stavanger University Hospitals, Norway. Eight hundred and fifty-five pregnant women were randomized to intervention or control groups. The intervention was a 12 week exercise program, includin...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To evaluate the influence of the urologist's experience on the surgical results and complications of transurethral resection of the prostate (TURP). Sixty-seven patients undergoing transurethral resection of the prostate without the use of a video camera were randomly allocated into three groups according to the urolog...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Recent studies have implicated the human cytomegalovirus (HCMV) as a possible pathogen for causing hypertension. We aimed to study the association between HCMV infection and hypertension in the United States National Health and Nutrition Examination Survey (NHANES). We analyzed data on 2979 men and 3324 women in the NH...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Figures from the British Defence Dental Services reveal that serving personnel in the British Army have a persistently lower level of dental fitness than those in the Royal Navy or the Royal Air Force. No research had been undertaken to ascertain if this reflects the oral health of recruits joining each Service. This s...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To determine whether the risk of secondary breast cancer after radiotherapy (RT) for Hodgkin's disease is greater among women who underwent RT around time of pregnancy. The records of 382 women treated with RT for Hodgkin's disease were reviewed and divided into those who received RT around the time of pregnancy and th...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
This study reviewed the results of performing day case laparoscopic cholecystectomy to assess the feasibility and safety of the procedure as a day case. This is a prospective study of 150 day case laparoscopic cholecystectomies performed between September 1999 and December 2004 under the care of the senior author. The ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Heterotopic ossification is a common complication after total hip arthroplasty. Non-steroidal anti-inflammatory drugs (NSAIDs) are known to prevent heterotopic ossifications effectively, however gastrointestinal complaints are reported frequently. In this study, we investigated whether etoricoxib, a selective cyclo-oxy...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
This study was designed to compare clinical effectiveness of operative with nonoperative treatment for displaced midshaft clavicular fractures (DMCF). We systematically searched electronic databases (MEDILINE, EMBASE, CLINICAL, OVID, BIOSIS and Cochrane registry of controlled clinical trials) to identify randomized con...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Treatment of HBeAg-negative chronic hepatitis B (CHB) with nucleos(t)ide analogues (NA) is usually indefinite, since the loss of HBsAg, as a criterion for its discontinuation, is a rare event. Recent evidence suggests that discontinuing NA therapy may be feasible in selected patients. To analyze the rate of virological...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Serum pancreatic lipase may improve the diagnosis of pancreatitis compared to serum amylase. Both enzymes have been measured simultaneously at our hospital allowing for a comparison of their diagnostic accuracy. Seventeen thousand five hundred and thirty-one measurements of either serum amylase and or serum pancreatic ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Precursor events are undesirable events that can lead to a subsequent adverse event and have been associated with postoperative mortality. The purpose of the present study was to determine whether precursor events are associated with a composite endpoint of major adverse cardiac events (MACE) (death, acute renal failur...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Our aim was to investigate the effects of growth hormone (GH), hyperbaric oxygen and combined therapy on normal and ischemic colonic anastomoses in rats. Eighty male Wistar rats were divided into eight groups (n = 10). In the first four groups, non-ischemic colonic anastomosis was performed, whereas in the remaining fo...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Previous studies have reported that the total bilirubin (TB) level is associated with coronary artery disease, heart failure and atrial fibrillation. These heart diseases can produce cardiogenic cerebral embolism and cause cardioembolic stroke. However, whether the serum TB could be a biomarker to differentiate cardioe...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Complications associated with blood transfusions have resulted in widespread acceptance of low hematocrit levels in surgical patients. However, preoperative anemia seems to be a risk factor for adverse postoperative outcomes in certain surgical patients. This study investigated the National Surgical Quality Improvement...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The purpose of this study was to retrospectively assess the potential benefits of delayed phase imaging series in routine CT scans of the abdomen and pelvis. Routine contrast-enhanced abdominopelvic CT scans of 1000 consecutively examined patients (912 men, 88 women; average age, 60 years; range, 22-94 years) were retr...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
"America's Best Hospitals," an influential list published annually by U.S. News and World Report, assesses the quality of hospitals. It is not known whether patients admitted to hospitals ranked at the top in cardiology have lower short-term mortality from acute myocardial infarction than those admitted to other hospit...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
This study represents a subset of a complete data set, considering only those children aged admitted to the Pediatric Surgery and Pediatric Nephrology Clinics during the period January 2011 to July 2012. In this study, we have determined that the QT interval changes significantly depending on the use of oxybutynin. The...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Family caregivers of dementia patients are at increased risk of developing depression or anxiety. A multi-component program designed to mobilize support of family networks demonstrated effectiveness in decreasing depressive symptoms in caregivers. However, the impact of an intervention consisting solely of family meeti...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To evaluate the outcome of a new modification of percutaneous needle suspension, using a bone anchor system for fixing the suture at the public bone, and to compare the results with those published previously. From March 1996, 37 patients with stress urinary incontinence (>2 years) were treated using a bone anchor syst...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To investigate the association between age-related macular degeneration (AMD) and the polymorphisms of HIF1A, a major vascular epithelial growth factor regulator under hypoxic conditions. The associations of AMD and polymorphisms of genes CFH, SKIV2L and MYRIP were also studied. Prospective study. Eighty-seven AMD pati...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Hyperleptinemia and oxidative stress play a major role in the development of cardiovascular diseases in obesity. This study aimed to investigate whether there is a relationship between plasma levels of leptin and phagocytic nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activity, and its potential relevanc...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
In January 2008, the Food and Drug Administration (FDA) communicated concerns and, in May 2009, issued a warning about an increased risk of suicidality for all antiepileptic drugs (AEDs). This research evaluated the association between the FDA suicidality communications and the AED prescription claims among members wit...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The aims of the study were to report the rates of recurrent and residual cholesteatoma following primary CAT surgery and to report the rate of conversion to a modified radical mastoidectomy. This was a retrospective review of a single surgeon series between 2006 and 2012. In total 132 second-look operations were undert...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To test the predictive value of distal ureteral diameter (UD) on reflux resolution after endoscopic injection in children with primary vesicoureteral reflux (VUR). This was a retrospective review of patients diagnosed with primary VUR between 2009 and 2012 who were managed by endoscopic injection. Seventy preoperative ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Manual resuscitation devices for infants and newborns must be able to provide adequate ventilation in a safe and consistent manner across a wide range of patient sizes (0.5-10 kg) and differing clinical states. There are little comparative data assessing biomechanical performance of common infant manual resuscitation d...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
To determine whether fibromyalgia (FM) is more common in patients with primary Sjögren's syndrome (pSS) who complain of fatigue. The association and prevalence of fatigue and FM was recorded in a group of patients with pSS and a control group of lupus patients, a subset of whom had secondary Sjögren's syndrome (sSS). 7...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Alexithymia is presumed to play an important predisposing role in the pathogenesis of medically unexplained physical symptoms. However, no research on alexithymia has been done among general medical outpatients who present with medically unexplained physical symptoms as their main problem and in which anxiety and depre...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
An increasingly significant public health issue in Canada, and elsewhere throughout the developed world, pertains to the provision of adequate palliative/end-of-life (P/EOL) care. Informal caregivers who take on the responsibility of providing P/EOL care often experience negative physical, mental, emotional, social and...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Laparoscopic sleeve gastrectomy (LSG) was initially performed as the first stage of biliopancreatic diversion with duodenal switch for the treatment of super-obese or high-risk obese patients but is now most commonly performed as a standalone operation. The aim of this prospective study was to investigate outcomes afte...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Mossy fibers are the sole excitatory projection from dentate gyrus granule cells to the hippocampus, forming part of the trisynaptic hippocampal circuit. They undergo significant plasticity during epileptogenesis and have been implicated in seizure generation. Mossy fibers are a highly unusual projection in the mammali...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To discuss and compare the results of suturing the nasal septum after septoplasty with the results of nasal packing. A prospective study, which was performed at Prince Hashem Military Hospital in Zarqa, Jordan and Prince Rashed Military Hospital in Irbid, Jordan between September 2005 and August 2006 included 169 conse...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Some patients with suspected common bile duct (CBD) stones are found to have sludge and no stones. Although sludge in the gallbladder is a precursor of gallbladder stones, the significance of bile duct sludge (BDS) is poorly defined. This study aimed to compare BDS with bile duct stones in terms of frequency, associate...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Retrospective outcome measurement study. The purpose of this study is to assess whether ossification of the posterior longitudinal ligament (OPLL) affects neurologic outcomes in patients with acute cervical spinal cord injury (SCI). There have so far been few reports examining the relationship between OPLL and SCI and ...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Laparoscopic colectomy has developed rapidly with the explosion of technology. In most cases, laparoscopic resection is performed for colorectal cancer. Intraoperative staging during laparoscopic procedure is limited. Laparoscopic ultrasonography (LUS) represents the only real alternative to manual palpation during lap...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To compare the results between a sliding compression hip screw and an intramedullary nail in the treatment of pertrochanteric fractures. Prospective computer-generated randomization of 206 patients into two study groups: those treated by sliding compression hip screw (Group 1; n = 106) and those treated by intramedulla...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
All VLBW infants from January 2008 to December 2012 with positive blood culture beyond 72 hours of life were enrolled in a retrospective cohort study. Newborns born after June 2010 were treated with IgM-eIVIG, 250 mg/kg/day iv for three days in addition to standard antibiotic regimen and compared to an historical cohor...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Acupuncture has been successfully used in myofascial pain syndromes. However, the number of needles used, that is, the dose of acupuncture stimulation, to obtain the best antinociceptive efficacy is still a matter of debate. The question was addressed comparing the clinical efficacy of two different therapeutic schemes...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The apparent favorable effect of alcohol on the risk of acute myocardial infarction (MI) may be related to its hypoinsulinemic effect when consumed with meals. We studied how the timing of alcohol consumption in relation to meals might affect the risk of MI in a population with relatively high regular alcohol consumpti...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The differential diagnosis between essential tremor (ET) and Parkinson's disease (PD) may be, in some cases, very difficult on clinical grounds alone. In addition, it is accepted that a small percentage of ET patients presenting symptoms and signs of possible PD may progress finally to a typical pattern of parkinsonism...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The mode of delivery depends on multiple parameters. After assisted reproductive technology (ART), previous studies have shown elevated C-section rates but few studies differentiated between elective and emergency operations and different protocols of cryopreservation. Because these studies did not use multiparity as e...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To our knowledge there are no evidence-based medicine data to date to critically judge the vulnerability of a solitary kidney to warm ischemia compared to paired kidneys. Ten dogs were exposed to open right nephrectomy to create a solitary kidney model (group 1). Ten dogs with both kidneys were considered group 2. All ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Many insurance payors mandate that bariatric surgery candidates undergo a medically supervised weight management (MSWM) program as a prerequisite for surgery. However, there is little evidence to support this requirement. We evaluated in a randomized controlled trial the hypothesis that participation in a MSWM program ...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The authors determine whether prevention influences the use of health services. Fluoridation's effect on restorative dental demand among 972 Washington state employees and spouses, aged 20 to 34 years, in two fluoridated communities and a nonfluoridated community was examined. At baseline, adults were interviewed by te...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Patient outcome after resection of colorectal liver metastases (CLM) following second-line preoperative chemotherapy (PCT) performed for insufficient response or toxicity of the first-line, is little known and has here been compared to the outcome following first-line. From January 2005 to June 2013, 5624 and 791 conse...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To determine whether prophylactic inhaled heparin is effective for the prevention and treatment of pneumonia patients receiving mechanical ventilation (MV) in the intensive care unit. A phase 2, double blind randomized controlled trial stratified for study center and patient type (non-operative, post-operative) was con...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To evaluate feasibility of the guidelines of the Groupe Francophone de Réanimation et Urgence Pédiatriques (French-speaking group of paediatric intensive and emergency care; GFRUP) for limitation of treatments in the paediatric intensive care unit (PICU). A 2-year prospective survey. A 12-bed PICU at the Hôpital Jeanne...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Despite rapid adoption of the Hirsch index (h-index) as a measure of academic success, the correlations between the h-index and other metrics of productivity remain poorly understood. The aims of this study were to determine whether h-indices were associated with greater National Institutes of Health (NIH) funding succ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To examine longitudinal patterns in body mass index (BMI) over 14 years and its association with knee pain in the Chingford Study. We studied a total of 594 women with BMI data from clinic visits at years (Y) 1, 5, 10, and 15. Knee pain at Y15 was assessed by questionnaire. Associations between BMI over 14 years and kn...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To evaluate whether a well developed collateral circulation predisposes to restenosis after percutaneous coronary intervention (PCI). Prospective observational study. 58 patients undergoing elective single vessel PCI in a tertiary referral interventional cardiac unit in the UK. Collateral flow index (CFI) was calculate...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
(1) To describe the prevalence of general practitioner visits and hospitalization according to sex and age groups; (2) to identify which factors are independently associated with a higher use of health care services among elderly Spanish; and (3) to study the time trends in the prevalence of use of health care services...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The cytomorphology of liquid-based preparations in urine cytology is different than classic slide preparations. To compare the performance of liquid-based preparation specimens to classically prepared urine specimens with a malignant diagnosis in the College of American Pathologists Interlaboratory Comparison Program i...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Trauma centers are designated to provide systematized multidisciplinary care to injured patients. Effective trauma systems reduce patient mortality by facilitating the treatment of injured patients at appropriately resourced hospitals. Several U.S. studies report reduced mortality among patients admitted directly to a ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Traditional resectional techniques and chordal transfer are difficult to apply in video-assisted mitral valve repair. Using artificial chords appears easier in this setting. The purpose of this study was to review the effectiveness and reproducibility of neochordal repair as a routine approach to minimally invasive mit...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The purpose of this study was to evaluate the impact of a patient-safety curriculum administered during a paediatric clerkship on medical students' attitudes towards patient safety. Medical students viewed an online video introducing them to systems-based analyses of medical errors. Faculty presented an example of a me...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
The route of delivery in eclampsia is controversial. We hypothesized that adverse maternal and perinatal outcomes may not be improved by early cesarean delivery. This was a randomized controlled exploratory trial carried out in a rural teaching institution. In all, 200 eclampsia cases, carrying ≥34 weeks, were allocate...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Occlusion of the atherosclerotic ascending aorta by an endoaortic inflatable balloon has been proposed as an alternative to conventional cross-clamping to prevent injury to the vessel and distal embolization of debris. The safety and the effectiveness of endoaortic occlusion have not been documented in this setting. En...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Opioid-dependent patients often have co-occurring chronic illnesses requiring medications that interact with methadone. Methadone maintenance treatment (MMT) is typically provided separately from medical care. Hence, coordination of medical care and substance use treatment is important to preserve patient safety. To id...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
There is an urgent need to increase opportunistic screening for sexually transmitted infections (STIs) in community settings, particularly for those who are at increased risk including men who have sex with men (MSM). The aim of this qualitative study was to explore whether home sampling kits (HSK) for multiple bacteri...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
The present analysis compares two palliative treatment concepts for lung cancer in terms of overall survival. Survival data from 207 patients were used in a retrospective analysis. All patients received palliative treatment comprising either 25 Gy applied in 5 fractions or 50 Gy in 20 fractions. A subgroup analysis was...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
We aimed to investigate the glomerular hyperfiltration due to pregnancy in women with more parities. Five hundred women aged 52.57 +/- 8.08 years, without a history of hypertension, diabetes mellitus or complicated pregnancy were involved in the study. They were divided into three groups. Group 1: women with no or one ...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
A side-to-side difference in systolic brachial arterial blood pressure is a common finding in subclavian artery stenosis and is frequently used as a screening tool for subclavian steal syndrome (SSS). It was the goal of this retrospective study to investigate the relationship between different vertebral artery waveform...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To assess Internet use amongst young people to determine whether it would be a practical way to provide sex education and information. Year 10 students (aged 14-15 years) from North Nottinghamshire schools were asked to participate in focus groups to discuss the Internet. A series of predefined questions were directed ...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Arterial calcification is a significant cardiovascular risk factor in hemodialysis patients. A series of factors are involved in the process of arterial calcification; however, the relationship between malnutrition and arterial calcification is still unclear. 68 hemodialysis patients were enrolled in this study. Nutrit...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To compare in vitro fertilization (IVF) outcomes in low responders stimulated with microdose leuprolide protocol (ML) following pretreatment with either oral contraceptive pill (OCP) or luteal estradiol (E2) + GnRH antagonist (E2 + antag) for follicular synchronization prior to controlled ovarian hyperstimulation (COH)...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The alterations of echocardiography and electrocardiogram (ECG) in patients received left atrial appendage LAA occlusion therapy are still unclear. The present study was to evaluate the influence of LAA occlusion device on echocardiography and ECG changes in patients with atrial fibrillation (AF). Seventy-three patient...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To show the results of treating posterior uveal melanomas with 106Ru plaque beta-ray radiotherapy and to review and discuss the literature concerning the optimal apical dose prescription (100 vs. 160 Gy). Forty-eight patients with uveal melanomas (median height 3.85 mm + 1 mm sclera) were treated with ruthenium plaques...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
We have reported previously that cerulein-induced edematous pancreatitis would transform into hemorrhagic pancreatitis by administration of endothelin-1 in rats. In the present study, we tried to protect rat model from developing into hemorrhagic pancreatitis with BQ123 (an ETA receptor antagonist). The rat model was m...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
This study was performed to describe the treatment plan modifications after a geriatric oncology clinic. Assessment of health and functional status and cancer assessment was performed in older cancer patients referred to a cancer center. Between June 2004 and May 2005, 105 patients 70 years old or older referred to a g...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Previous studies reported that breast-feeding protects children against a variety of diseases, but these studies were generally conducted on "high-risk" or hospitalized children. This paper describes the results of our study on the effects of breast-feeding on rate of illness in normal children with a family history of...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To assess whether eligibility to an adjuvant chemotherapy protocol in itself represents a good prognostic factor after radical cystectomy for bladder cancer. Between April 1984 and May 1989, our institution entered 35 patients with invasive bladder cancer into the Swiss Group for Clinical and Epidemiological Cancer Res...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To measure the dimensions of compensatory hypertrophy of the middle turbinate in patients with nasal septal deviation, before and after septoplasty. The mucosal and bony structures of the middle turbinate and the angle of the septum were measured using radiological analysis before septoplasty and at least one year afte...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To determine the therapeutic effect (alleviation of vascular type headache) and side effects of a slow intravenous metoclopramide infusion over 15 min compared with those effects of a bolus intravenous metoclopramide infusion over 2 min in the treatment of patients with recent onset vascular type headache. All adults t...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Tuberculosis (TB) patients face numerous difficulties adhering to the long-term, rigorous TB treatment regimen. Findings on TB patients' treatment adherence vary across existing literature and official reports. The present study attempted to determine the actual treatment adherence of new TB patients and to identify fa...
{ "A": "yes", "B": "no", "C": "maybe" }
maybe
C
Anteroposterior, lateral, and right and left oblique lumbar spine radiographs are often a standard part of the evaluation of children who are clinically suspected of having spondylolysis. Recent concerns regarding radiation exposure and costs have brought the value of oblique radiographs into question. The purpose of t...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
It is generally believed that positioning of the patient in a head-down tilt (Trendelenberg position) decreases the likelihood of a venous air embolism during liver resection. The physiological effect of variation in horizontal attitude on central and hepatic venous pressure was measured in 10 patients during liver sur...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
As part of the staging procedure in squamous cell carcinoma of the penis, we assessed the role of ultrasound examination, in particular its role in assessing the extent and the invasion into the corpora. From 1988 until 1992, all patients referred for primary treatment underwent ultrasound assessment with a 7.5 MHz lin...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To determine the effect of prior benign prostate biopsies on the surgical and clinical outcomes of patients treated with radical perineal prostatectomy for prostate cancer. A total of 1369 patients with clinically localized prostate cancer underwent radical prostatectomy by a single surgeon between 1991 and 2001. A sub...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Minority patients with cancer experience worse control of their pain than do their white counterparts. This disparity may, in part, reflect more miscommunication between minority patients and their physicians. Therefore, we examined whether patient coaching could reduce disparities in pain control in a secondary analys...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
Currently the choice of breast cancer therapy is based on prognostic factors. The proliferation marker Ki-67 is used increasingly to determine the method of therapy. The current study analyses the predictive value of Ki-67 in foreseeing breast cancer patients' responses to neoadjuvant chemotherapy. This study includes ...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
To evaluate the accuracy of ultrasonographic examination in boys with an undescended testis. All patients who were referred to the paediatric surgeon after detection of an undescended testis were evaluated prospectively between November 2001 and November 2004. Among these 377 patients, 87 were referred with an ultrason...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
After 34 weeks gestation, summary measures of location for birthweight (e.g means and centiles) increase more slowly for Australian Aborigines than for whites. A similar pattern has been observed for blacks in the US. This study tests whether the reported pattern is due to differential misclassification of gestational ...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
The reduced use of sugars-containing (SC) liquid medicines has increased the use of other dose forms, potentially resulting in more widespread dental effects, including tooth wear. The aim of this study was to assess the erosive potential of 97 paediatric medicines in vitro. The study took the form of in vitro measurem...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
This investigation assesses the effect of platelet-rich plasma (PRP) gel on postoperative pain, swelling, and trismus as well as healing and bone regeneration potential on mandibular third molar extraction sockets. A prospective randomized comparative clinical study was undertaken over a 2-year period. Patients requiri...
{ "A": "yes", "B": "no", "C": "maybe" }
yes
A
An unknown number of colorectal cancers could be due to missed adenomas during previous endoscopy. Data in the literature are sparse. A large cross-sectional study was done in a prospective database of all patients diagnosed with colorectal cancer. All consecutive endoscopies over a period of 15 years, in which colorec...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
We analyzed the pharmacokinetic-pharmacodynamic relationship of vancomycin to determine the drug exposure parameters that correlate with the efficacy and nephrotoxicity of vancomycin in patients with methicillin-resistant Staphylococcus aureus pneumonia and evaluated the need to use peak concentration in therapeutic dr...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
Although desflurane is commonly used to control surgically induced hypertension, its effects on left ventricular (LV) function have not been investigated in this clinical situation. The purpose of the present study was to evaluate the LV function response to desflurane, when used to control intraoperative hypertension....
{ "A": "yes", "B": "no", "C": "maybe" }
no
B
To assess whether Indigenous Australians age prematurely compared with other Australians, as implied by Australian Government aged care policy, which uses age 50 years and over for population-based planning for Indigenous people compared with 70 years for non-indigenous people. Cross-sectional analysis of aged care ass...
{ "A": "yes", "B": "no", "C": "maybe" }
no
B