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Does Knockout of Hlx in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Hlx
cell cycle progression
breast epithelium
Gene: Hlx (H2.0-like homeobox) Type: protein-coding Summary: Predicted to enable sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic digestive tract morphogenesis; enteric nervous system development; and regulation of T-helper cell differentiation. P...
Does Knockout of Snrnp48 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Snrnp48
response to virus
Embryonic Fibroblast Cell Line
Gene: Snrnp48 (small nuclear ribonucleoprotein 48 (U11/U12)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, biological_process, mRNA processing; MF: metal ion binding, molecular_function, zinc ion binding; CC: U12-type spliceosomal complex, cytosol, nucleop...
Does Knockout of Vmn2r96 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Vmn2r96
cell viability
Immortal mouse chromaffin cells
Gene: Vmn2r96 (vomeronasal 2, receptor 96) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: H3BJR...
Does Knockout of Srpk3 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Srpk3
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Srpk3 (serine/arginine-rich protein specific kinase 3) Type: protein-coding Summary: Enables protein serine/threonine kinase activity. Involved in muscle tissue development. Acts upstream of or within protein phosphorylation and skeletal muscle tissue development. Predicted to be active in cytopla...
Does Knockout of Papss1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Papss1
protein/peptide distribution
myoblast cell line
Gene: Papss1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process, sulfate assimilation; MF: ATP binding, adenylylsulfate kinase activity, catalytic activity, kinase a...
Does Knockout of Mcm7 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Mcm7
cell proliferation
Embryonic Stem Cell Line
Gene: Mcm7 (minichromosome maintenance complex component 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, cell population proliferation, cellular respons...
Does Knockout of Papolg in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Papolg
protein/peptide distribution
Microglial Cell Line
Gene: Papolg (poly(A) polymerase gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA 3'-end processing, mRNA processing; MF: ATP binding, RNA binding, metal ion binding, nucleotide binding, nucleotidyltransferase activity, poly(A) RNA polymerase activity, transfera...
Does Knockout of Ceacam12 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Ceacam12
cell proliferation
Embryonic Stem Cell Line
Gene: Ceacam12 (CEA cell adhesion molecule 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, immune response, phagocytosis; CC: cellular_component, external side of plasma membrane Pathways: UniProt: Q9DAS5, Q3V2Q3, Q3UKP4, Q9DAZ3 ...
Does Knockout of Syp in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Syp
cell proliferation
Embryonic Stem Cell Line
Gene: Syp (synaptophysin) Type: protein-coding Summary: Enables SH2 domain binding activity and identical protein binding activity. Involved in regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity; and regulation of synaptic vesicle priming. Located...
Does Knockout of Phf5a in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Phf5a
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Phf5a (PHD finger protein 5A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, positive regulation of DNA-templated transcription, stem cell differentiation; MF: DNA binding, RNA binding, metal ion bindin...
Does Knockout of Tas2r124 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tas2r124
protein/peptide distribution
myoblast cell line
Gene: Tas2r124 (taste receptor, type 2, member 124) Type: protein-coding Summary: Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste and positive regulation of cytokinesis. Predicted to be active i...
Does Knockout of Skor2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Skor2
response to virus
Microglial Cell Line
Gene: Skor2 (SKI family transcriptional corepressor 2) Type: protein-coding Summary: Enables SMAD binding activity; chromatin binding activity; and histone deacetylase binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, i...
Does Knockout of Coa6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Coa6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Coa6 (cytochrome c oxidase assembly factor 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial cytochrome c oxidase assembly, respiratory chain complex IV assembly; MF: copper ion binding; CC: mitochondrial intermembrane space, mitochondrion, nucleoplas...
Does Knockout of Txndc17 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Txndc17
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Txndc17 (thioredoxin domain containing 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular oxidant detoxification, tumor necrosis factor-mediated signaling pathway; MF: peroxidase activity, protein-disulfide reductase [NAD(P)H] activity; CC: cytoplasm, cyto...
Does Knockout of Srr in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Srr
cell proliferation
Mouse kidney carcinoma cell
Gene: Srr (serine racemase) Type: protein-coding Summary: Enables several functions, including amino-acid racemase activity; anion binding activity; and identical protein binding activity. Acts upstream of or within D-serine biosynthetic process and L-serine metabolic process. Predicted to be located in...
Does Knockout of Riok1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Riok1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Riok1 (RIO kinase 1) Type: protein-coding Summary: This gene encodes a member of the RIO family of atypical serine protein kinases. A similar protein in humans is a component of the protein arginine methyltransferase 5 complex that specifically recruits the RNA-binding protein nucleolin as a methy...
Does Knockout of Gtf2a1l in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Gtf2a1l
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Gtf2a1l (general transcription factor IIA, 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cognition, transcription by RNA polymerase II, transcription initiation at RNA polymerase II promoter; MF: DNA binding, protein binding; CC: cytoplasm, male germ cell ...
Does Knockout of Rab8a in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rab8a
cell proliferation
Embryonic Stem Cell Line
Gene: Rab8a (RAB8A, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, Golgi vesicle fusion to target membrane, autophagy, axonogenesis, cell projection organization, cellular response to insulin stimulus, cilium assembly, endo...
Does Knockout of Lrrc20 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Lrrc20
cell proliferation
Mouse kidney carcinoma cell
Gene: Lrrc20 (leucine rich repeat containing 20) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8CI70 Entrez ID: 216011
Does Knockout of Nars2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Nars2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nars2 (asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)) Type: protein-coding Summary: Predicted to enable asparagine-tRNA ligase activity. Predicted to be involved in asparaginyl-tRNA aminoacylation. Located in mitochondrion. Is expressed in embryo; extraembryonic component; and primitive ...
Does Knockout of Sirt1 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Sirt1
cell viability
Immortal mouse chromaffin cells
Gene: Sirt1 (sirtuin 1) Type: protein-coding Summary: This gene encodes a member of the sirtuin family of proteins, characterized by their deacetylase activity and proposed role in longevity. The encoded protein regulates gene expression in a wide range of cell and tissue types through its NAD+-dependen...
Does Knockout of Cldnd2 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Cldnd2
protein/peptide accumulation
Mouse cell
Gene: Cldnd2 (claudin domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, plasma membrane Pathways: UniProt: Q9D9H2 Entrez ID: 74276
Does Knockout of Flt3 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Flt3
cell proliferation
Colonic Cancer Cell Line
Gene: Flt3 (FMS-like tyrosine kinase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, animal organ development, antigen processing and presentation, cell migration, cell surface receptor protein tyrosine kinase signaling pathway, cell surface rec...
Does Knockout of Tll1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Tll1
protein/peptide accumulation
Regulatory T cell
Gene: Tll1 (tolloid-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, dorsal/ventral pattern formation, protein processing, proteolysis; MF: calcium ion binding, collagen binding, hydrolase activity, metal ion binding, metalloendopeptidase activi...
Does Knockout of Hspd1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Hspd1
cell proliferation
Colonic Cancer Cell Line
Gene: Hspd1 (heat shock protein 1 (chaperonin)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, B cell proliferation, MyD88-dependent toll-like receptor signaling pathway, T cell activation, adhesion of symbiont to host, apoptotic mitochondrial changes,...
Does Knockout of Ccr3 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Ccr3
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ccr3 (C-C motif chemokine receptor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERK1 and ERK2 cascade, G protein-coupled receptor signaling pathway, angioblast cell migration, calcium-mediated signaling, cell chemotaxis, chemokine-mediated signaling pathway, c...
Does Knockout of Kdm8 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Kdm8
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Kdm8 (lysine (K)-specific demethylase 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G2/M transition of mitotic cell cycle, chromatin organization, chromatin remodeling, circadian regulation of gene expression, fibroblast proliferation, in utero embryonic develo...
Does Knockout of Nle1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Nle1
cell viability
Immortal mouse chromaffin cells
Gene: Nle1 (notchless homolog 1) Type: protein-coding Summary: Acts upstream of or within several processes, including chordate embryonic development; hematopoietic stem cell homeostasis; and positive regulation of canonical Wnt signaling pathway. Located in nucleolus. Is expressed in several structures...
Does Knockout of Sqstm1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Sqstm1
cell proliferation
Embryonic Stem Cell Line
Gene: Sqstm1 (sequestosome 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aggrephagy, apoptotic process, autophagy, brown fat cell proliferation, cell differentiation, cellular response to stress, endosome organization, energy homeostasis, immune system process, macro...
Does Knockout of Dnajc5g in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Dnajc5g
cell proliferation
Melanoma Cell Line
Gene: Dnajc5g (DnaJ heat shock protein family (Hsp40) member C5 gamma) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, cytoplasm, membrane Pathways: Protein processing in endoplasmic reticulum - Mus musculus (mouse) UniProt: A0A087WQK...
Does Knockout of Lyve1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Lyve1
protein/peptide accumulation
Embryonic Cell Line
Gene: Lyve1 (lymphatic vessel endothelial hyaluronan receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, glycosaminoglycan catabolic process, hyaluronan catabolic process, positive regulation of cellular extravasation, receptor-mediated endocytosis;...
Does Knockout of Plekhb2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Plekhb2
cell proliferation
Mouse kidney carcinoma cell
Gene: Plekhb2 (pleckstrin homology domain containing, family B (evectins) member 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: endosome, membrane, recycling endosome membrane Pathways: UniProt: Q9QZC7 Entrez ID: 226971
Does Knockout of Atxn10 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Atxn10
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Atxn10 (ataxin 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cilium assembly, nervous system development, neuron projection development, plasma membrane bounded cell projection organization, regulation of cytokinesis; MF: enzyme binding, identic...
Does Knockout of Slc12a9 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Slc12a9
autophagy
Embryonic Fibroblast Cell Line
Gene: Slc12a9 (solute carrier family 12 (potassium/chloride transporters), member 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell volume homeostasis, chloride ion homeostasis, chloride transmembrane transport, inorganic cation transmembrane transport, metal ion tr...
Does Knockout of Rhbdf1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Rhbdf1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rhbdf1 (rhomboid 5 homolog 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration, cell population proliferation, negative regulation of protein secretion, regulation of epidermal growth factor receptor signaling pathway, regulation of proteasomal protein...
Does Knockout of Vmn2r121 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Vmn2r121
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Vmn2r121 (vomeronasal 2, receptor 121) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A...
Does Knockout of Cdc42ep1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Cdc42ep1
cell proliferation
Embryonic Stem Cell Line
Gene: Cdc42ep1 (CDC42 effector protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, positive regulation of actin filament polymerization, positive regulation of pseudopodium assembly, regulation of cell shape; MF: protein binding, sm...
Does Knockout of Ndufs5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Ndufs5
cell proliferation
Mouse kidney carcinoma cell
Gene: Ndufs5 (NADH:ubiquinone oxidoreductase core subunit S5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, mitochondrial respiratory chain complex I assembly, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner...
Does Knockout of Morc2a in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Morc2a
cell proliferation
Embryonic Stem Cell Line
Gene: Morc2a (microrchidia 2A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, chromatin remodeling, constitutive heterochromatin formation, transposable element silencing by heterochromatin formation; MF: ATP binding, ATP hydrolysis activity, chromat...
Does Knockout of Mettl15 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Mettl15
cell proliferation
Embryonic Stem Cell Line
Gene: Mettl15 (methyltransferase like 15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, rRNA base methylation; MF: methyltransferase activity, rRNA (cytosine-N4-)-methyltransferase activity, transferase activity; CC: mitochondrial matrix, mitochondrion ...
Does Knockout of Zbtb7b in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Zbtb7b
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Zbtb7b (zinc finger and BTB domain containing 7B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NK T cell differentiation, adaptive thermogenesis, cell differentiation, lactation, negative regulation of CD8-positive, alpha-beta T cell differentiation, negative reg...
Does Knockout of Dppa2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Dppa2
cell viability
Immortal mouse chromaffin cells
Gene: Dppa2 (developmental pluripotency associated 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epigenetic regulation of gene expression, lung-associated mesenchyme development, positive regulation of stem cell proliferation, stem cell population maintenance, system...
Does Knockout of Slc51b in Melanoma Cell Line causally result in cell proliferation?
0
2,491
Knockout
Slc51b
cell proliferation
Melanoma Cell Line
Gene: Slc51b (solute carrier family 51, beta subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bile acid and bile salt transport, bile acid secretion, lipid transport, positive regulation of protein exit from endoplasmic reticulum, positive regulation of protein gl...
Does Knockout of Eaf1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Eaf1
cell proliferation
Melanoma Cell Line
Gene: Eaf1 (ELL associated factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, regulation of transcription elongation by RNA polymerase II, transcription elongation by RNA polymerase II; MF: transcription el...
Does Knockout of Dab2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Dab2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dab2 (disabled 2, mitogen-responsive phosphoprotein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, apoptotic process, cell differentiation, cell morphogenesis, cellular response to epidermal growth factor stimulus, cellular response to trans...
Does Knockout of Rab5a in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Rab5a
protein/peptide distribution
myoblast cell line
Gene: Rab5a (RAB5A, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: amyloid-beta clearance by transcytosis, canonical Wnt signaling pathway, early endosome to late endosome transport, endocytosis, endosomal transport, host-mediated perturbation...
Does Knockout of Trim60 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Trim60
protein/peptide accumulation
Embryonic Cell Line
Gene: Trim60 (tripartite motif-containing 60) Type: protein-coding Summary: No summary available. Gene Ontology: BP: canonical NF-kappaB signal transduction, innate immune response, negative regulation of non-canonical NF-kappaB signal transduction, non-canonical NF-kappaB signal transduction, ...
Does Knockout of Dars2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Dars2
response to virus
Microglial Cell Line
Gene: Dars2 (aspartyl-tRNA synthetase 2 (mitochondrial)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aspartyl-tRNA aminoacylation, mitochondrial asparaginyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation, translation; MF: ATP bin...
Does Knockout of Fgf15 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Fgf15
cell proliferation
Embryonic Stem Cell Line
Gene: Fgf15 (fibroblast growth factor 15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fibroblast growth factor receptor signaling pathway, heart development, negative regulation of bile acid biosynthetic process, negative regulation of gene expression, neural crest ce...
Does Knockout of Taf12 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Taf12
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Taf12 (TATA-box binding protein associated factor 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription initiation, RNA polymerase II preinitiation complex assembly, mRNA transcription by RNA polymerase II, positive regulation of DNA-templa...
Does Knockout of Adgre5 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Adgre5
cell viability
Immortal mouse chromaffin cells
Gene: Adgre5 (adhesion G protein-coupled receptor E5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cell adhesion, cell surface receptor signaling pathway, positive regulation of synapse assembly, signal transduction; MF: G ...
Does Knockout of Irf8 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Irf8
cell proliferation
Embryonic Stem Cell Line
Gene: Irf8 (interferon regulatory factor 8) Type: protein-coding Summary: The protein encoded by this gene is a transcription factor that belongs to the interferon regulatory factor family. Proteins belonging to this family have a DNA binding domain at the amino terminus that contains five well-conserve...
Does Knockout of Mau2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Mau2
cell proliferation
Embryonic Stem Cell Line
Gene: Mau2 (MAU2 sister chromatid cohesion factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, chromosome segregation, maintenance of mitotic sister chromatid cohesion, mitotic sister chromatid cohesion; CC: SMC loading complex, Scc2-Scc4 cohesin loadin...
Does Knockout of Map3k14 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Map3k14
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Map3k14 (mitogen-activated protein kinase kinase kinase 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, cellular response to mechanical stimulus, defense response to virus, immune response, non-canonical NF-kappaB signal transduction; MF: ATP bindi...
Does Knockout of Nfe2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Nfe2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nfe2 (nuclear factor, erythroid derived 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell-cell signaling, gene expression, labyrinthine layer blood vessel development, negative regulation of bone mineralization, negative regulation of cell population prolifera...
Does Knockout of Scgb1b27 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Scgb1b27
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Scgb1b27 (secretoglobin, family 1B, member 27) Type: protein-coding Summary: No summary available. Gene Ontology: MF: steroid binding; CC: cytoplasm, extracellular region Pathways: UniProt: G3UXN8, Q91WB5 Entrez ID: 11354
Does Knockout of Atp2b1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Atp2b1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Atp2b1 (ATPase, Ca++ transporting, plasma membrane 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion export, calcium ion export across plasma membrane, calcium ion transmembrane transport, calcium ion transport, intracellular calcium ion homeostasis, mo...
Does Knockout of Psmg4 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Psmg4
cell proliferation
Melanoma Cell Line
Gene: Psmg4 (proteasome (prosome, macropain) assembly chaperone 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, proteasome assembly; MF: molecular_function, protein binding, protein-containing complex binding; CC: cytosol, protein-containing complex...
Does Knockout of Cuedc2 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Cuedc2
cell proliferation
Regulatory T cell
Gene: Cuedc2 (CUE domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of cytokine production involved in inflammatory response, negative regulation of macrophage cytokine production; MF: molecular_function, ubiquitin binding; CC: cytop...
Does Knockout of Dip2a in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Dip2a
protein/peptide distribution
myoblast cell line
Gene: Dip2a (disco interacting protein 2 homolog A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetyl-CoA biosynthetic process, dendritic spine morphogenesis, negative regulation of gene expression, nervous system development, positive regulation of peptidyl-lysine a...
Does Knockout of Chchd1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Chchd1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Chchd1 (coiled-coil-helix-coiled-coil-helix domain containing 1) Type: protein-coding Summary: Predicted to be involved in mitochondrial translation. Located in mitochondrion. Orthologous to human CHCHD1 (coiled-coil-helix-coiled-coil-helix domain containing 1). [provided by Alliance of Genome Res...
Does Knockout of Ddx52 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Ddx52
cell proliferation
Embryonic Stem Cell Line
Gene: Ddx52 (DExD box helicase 52) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of SSU-rRNA; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nucleic acid binding, nucleotide binding; CC: nu...
Does Knockout of Tgif1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Tgif1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tgif1 (TGFB-induced factor homeobox 1) Type: protein-coding Summary: Enables chromatin binding activity. Acts upstream of or within several processes, including negative regulation of retinoic acid receptor signaling pathway; positive regulation of amacrine cell differentiation; and regionalizatio...
Does Knockout of Fhod3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Fhod3
cell proliferation
Mouse kidney carcinoma cell
Gene: Fhod3 (formin homology 2 domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament network formation, actin filament organization, cardiac myofibril assembly, negative regulation of actin filament polymerization, positive regulation of stre...
Does Knockout of Scube1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Scube1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Scube1 (signal peptide, CUB domain, EGF-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of smoothened signaling pathway, signal transduction; MF: calcium ion binding, identical protein binding, protein binding; CC: cell surface, external ...
Does Knockout of Cela3a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Cela3a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cela3a (chymotrypsin-like elastase family, member 3A) Type: protein-coding Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Orthologous to several human genes including CELA3B (chymotrypsin like...
Does Knockout of Cd14 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Cd14
autophagy
Embryonic Fibroblast Cell Line
Gene: Cd14 (CD14 antigen) Type: protein-coding Summary: This gene encodes a protein that plays an important role in the innate immune response and is expressed in monocyte/macrophage cells. This gene product acts as a co-receptor that binds several microbial and fungal molecules, including lipopolysacch...
Does Knockout of Ubap2 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Ubap2
protein/peptide accumulation
Mouse cell
Gene: Ubap2 (ubiquitin-associated protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: chromosome, cytoplasm, nucleus Pathways: UniProt: Q91VX2 Entrez ID: 68926
Does Knockout of Faap20 in Lymphoma Cell Line causally result in response to chemicals?
0
1,535
Knockout
Faap20
response to chemicals
Lymphoma Cell Line
Gene: Faap20 (Fanconi anemia core complex associated protein 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, interstrand cross-link repair, translesion synthesis; MF: K63-linked polyubiquitin modification-dependent protein binding, met...
Does Knockout of Rps5 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Rps5
response to virus
Microglial Cell Line
Gene: Rps5 (ribosomal protein S5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, regulation of translational fidelity, ribosomal small subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, mRNA b...
Does Knockout of Rnft1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Rnft1
cell proliferation
Melanoma Cell Line
Gene: Rnft1 (ring finger protein, transmembrane 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of ERAD pathway, protein autoubiquitination, protein ubiquitination; MF: metal ion binding, transferase activity, ubiquitin binding, ubiquitin protein li...
Does Knockout of Nefh in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Nefh
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nefh (neurofilament, heavy polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon development, axon regeneration, axonogenesis, cellular response to leukemia inhibitory factor, intermediate filament bundle assembly, intermediate filament cytoskeleton orga...
Does Knockout of 4921524L21Rik in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
4921524L21Rik
protein/peptide accumulation
Mouse cell
Gene: 4921524L21Rik (RIKEN cDNA 4921524L21 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A3Q4EGB9, Q9D5T2, A0A3Q4EGN5 Entrez ID: 70901
Does Knockout of Tbc1d13 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Tbc1d13
cell cycle progression
breast epithelium
Gene: Tbc1d13 (TBC1 domain family, member 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport; MF: GTPase activator activity, protein binding, small GTPase binding; CC: cytoplasm, cytosol, membrane Pathways: Membrane Trafficking, R...
Does Knockout of Ndufa1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Ndufa1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ndufa1 (NADH:ubiquinone oxidoreductase subunit A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion, respira...
Does Knockout of Ankfy1 in macrophage causally result in phagocytosis?
1
1,888
Knockout
Ankfy1
phagocytosis
macrophage
Gene: Ankfy1 (ankyrin repeat and FYVE domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to lysosome transport, endocytosis, endosomal transport, endosomal vesicle fusion, positive regulation of pinocytosis, retrograde transport, endosome to Golgi;...
Does Knockout of Spink14 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Spink14
cell proliferation
Mouse kidney carcinoma cell
Gene: Spink14 (serine peptidase inhibitor, Kazal type 14) Type: protein-coding Summary: Orthologous to human SPINK14 (serine peptidase inhibitor Kazal type 14 (putative)). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: CC: cellular_component, extracellular region P...
Does Activation of Ankrd23 in Mouse cell causally result in protein/peptide accumulation?
1
690
Activation
Ankrd23
protein/peptide accumulation
Mouse cell
Gene: Ankrd23 (ankyrin repeat domain 23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid metabolic process, positive regulation of transcription by RNA polymerase II, regulation of sarcomere organization, response to mechanical stimulus, response to muscle stre...
Does Knockout of Nfat5 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Nfat5
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nfat5 (nuclear factor of activated T cells 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA-templated transcription, R-loop processing, calcineurin-NFAT signaling cascade, cellular response to cytokine stimulus, negative regulation of urin...
Does Knockout of Fnta in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Fnta
cell proliferation
Melanoma Cell Line
Gene: Fnta (farnesyltransferase, CAAX box, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: enzyme-linked receptor protein signaling pathway, negative regulation of apoptotic process, nuclear envelope organization, peptide pheromone maturation, positive regulation o...
Does Knockout of Nek5 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Nek5
cell cycle progression
breast epithelium
Gene: Nek5 (NIMA (never in mitosis gene a)-related expressed kinase 5) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, kinase activity, metal ion binding, nucleotide binding, protein kinase activity, protein serine kinase activity, protein serine/threonine ki...
Does Knockout of Rce1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Rce1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rce1 (Ras converting CAAX endopeptidase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CAAX-box protein maturation, CAAX-box protein processing, proteolysis; MF: endopeptidase activity, exopeptidase activity, hydrolase activity, metalloendopeptidase activity, pe...
Does Knockout of Suds3 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Suds3
response to virus
Embryonic Fibroblast Cell Line
Gene: Suds3 (suppressor of defective silencing 3 homolog (S. cerevisiae)) Type: protein-coding Summary: Enables histone deacetylase binding activity and identical protein binding activity. Involved in negative regulation of DNA-templated transcription. Acts upstream of or within blastocyst hatching. Par...
Does Knockout of Cib4 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Cib4
protein/peptide distribution
myoblast cell line
Gene: Cib4 (calcium and integrin binding family member 4) Type: protein-coding Summary: No summary available. Gene Ontology: MF: calcium ion binding, magnesium ion binding, metal ion binding, molecular_function Pathways: UniProt: Q9D9N5 Entrez ID: 73259
Does Knockout of Elof1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Elof1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Elof1 (ELF1 homolog, elongation factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, transcription elongation by RNA polymerase II, transcription-coupled nucleotide-excision repair; MF: RNA polymerase II complex binding, protein...
Does Knockout of Mdn1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Mdn1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Mdn1 (midasin AAA ATPase 1) Type: protein-coding Summary: Predicted to be involved in ribosomal large subunit assembly and ribosomal large subunit export from nucleus. Predicted to be located in cytosol; intermediate filament cytoskeleton; and nuclear lumen. Predicted to be part of preribosome, la...
Does Knockout of Rhot2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Rhot2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rhot2 (ras homolog family member T2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular homeostasis, establishment of mitochondrion localization, microtubule-mediated, mitochondrial outer membrane permeabilization, mitochondrion organization, mitochondrion tra...
Does Knockout of Plekho1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Plekho1
cell proliferation
Colonic Cancer Cell Line
Gene: Plekho1 (pleckstrin homology domain containing, family O member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lamellipodium morphogenesis, myoblast fusion, myoblast migration, regulation of cell shape, regulation of myoblast fusion; CC: cytoplasm, membrane, mus...
Does Knockout of Sik2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Sik2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Sik2 (salt inducible kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, insulin receptor signaling pathway, intracellular signal transduction, lipid biosynthetic process, negative regulation of carbohydrate metabolic process, negative regulation...
Does Knockout of Ptpn11 in Melanoma Cell Line causally result in cell proliferation?
1
1,157
Knockout
Ptpn11
cell proliferation
Melanoma Cell Line
Gene: Ptpn11 (protein tyrosine phosphatase, non-receptor type 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Bergmann glial cell differentiation, DNA damage checkpoint signaling, ERBB signaling pathway, atrioventricular canal development, axonogenesis, brain developm...
Does Knockout of Maz in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Maz
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Maz (MYC-associated zinc finger protein (purine-binding transcription factor)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of apoptotic signaling pathway, negative regulation of transcription by RNA polymerase II, positive regulation of DNA-t...
Does Knockout of Fcf1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Fcf1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Fcf1 (FCF1 rRNA processing protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA ...
Does Knockout of Edil3 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Edil3
cell cycle progression
breast epithelium
Gene: Edil3 (EGF-like repeats and discoidin I-like domains 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, positive regulation of cell-substrate adhesion; MF: calcium ion binding, metal ion binding; CC: extracellular region, extracellular space ...
Does Knockout of Slc35f3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Slc35f3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Slc35f3 (solute carrier family 35, member F3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: thiamine transport; CC: cellular_component, membrane Pathways: UniProt: Q1LZI2 Entrez ID: 210027
Does Knockout of Lrriq1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Lrriq1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lrriq1 (leucine-rich repeats and IQ motif containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, biological_process, ectopic germ cell programmed cell death, gene expression, single fertilization Pathways: UniProt: Q0P5X1...
Does Knockout of Pdcd2l in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Pdcd2l
protein/peptide distribution
myoblast cell line
Gene: Pdcd2l (programmed cell death 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, biological_process Pathways: UniProt: Q8C5N5 Entrez ID: 68079
Does Knockout of Atxn2l in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Atxn2l
protein/peptide accumulation
Regulatory T cell
Gene: Atxn2l (ataxin 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA metabolic process, stress granule assembly; MF: RNA binding, mRNA binding; CC: cytoplasm, cytoplasmic stress granule, cytosol, membrane, nuclear speck, nucleus Pathways: Amyotrophic...
Does Knockout of Aagab in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Aagab
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Aagab (alpha- and gamma-adaptin binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, protein transport; CC: cytoplasm, cytosol, nuclear speck Pathways: UniProt: Q8R2R3 Entrez ID: 66939
Does Knockout of Nox1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Nox1
protein/peptide distribution
myoblast cell line
Gene: Nox1 (NADPH oxidase 1) Type: protein-coding Summary: This gene encodes a subunit of the NADPH oxidase enzyme, which is a membrane-bound, multisubunit protein. This complex catalyzes the transfer of electrons from NADPH to molecular oxygen to produce superoxide or hydrogen peroxide and may have a r...
Does Knockout of Cachd1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Cachd1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cachd1 (cache domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion transmembrane transport, calcium ion transport, monoatomic ion transport; CC: membrane, voltage-gated calcium channel complex Pathways: UniProt: Q6PDJ1 ...