prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of Klrb1c in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,684 | Knockout | Klrb1c | protein/peptide distribution | myoblast cell line | Gene: Klrb1c (killer cell lectin-like receptor subfamily B member 1C)
Type: protein-coding
Summary: Enables identical protein binding activity and signaling receptor activity. Acts upstream of or within natural killer cell activation and positive regulation of natural killer cell mediated cytotoxicity. ... |
Does Knockout of Ciao1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Ciao1 | cell proliferation | Melanoma Cell Line | Gene: Ciao1 (cytosolic iron-sulfur protein assembly 1)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation. Predicted to act upstream of or within regulation of transcription by RNA p... |
Does Knockout of Cdr2l in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,265 | Knockout | Cdr2l | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Cdr2l (cerebellar degeneration-related protein 2-like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: identical protein binding, molecular_function
Pathways:
UniProt: A2A6T1
Entrez ID: 237988 |
Does Knockout of Tsga10ip in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,288 | Knockout | Tsga10ip | cell proliferation | Mouse kidney carcinoma cell | Gene: Tsga10ip (testis specific 10 interacting protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cytoskeleton, photoreceptor connecting cilium
Pathways:
UniProt:
Entrez ID: 78306 |
Does Knockout of Plekhg2 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,440 | Knockout | Plekhg2 | protein/peptide accumulation | Embryonic Cell Line | Gene: Plekhg2 (pleckstrin homology domain containing, family G (with RhoGef domain) member 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: regulation of actin filament polymerization; MF: guanyl-nucleotide exchange factor activity, small GTPase binding
Pathway... |
Does Knockout of Intu in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,679 | Knockout | Intu | protein/peptide distribution | myoblast cell line | Gene: Intu (inturned planar cell polarity protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell projection organization, cilium assembly, embryonic digit morphogenesis, establishment of planar polarity, hair follicle morphogenesis, intraciliary transport, keratino... |
Does Knockout of Taf6l in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Taf6l | cell viability | Immortal mouse chromaffin cells | Gene: Taf6l (TATA-box binding protein associated factor 6 like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of DNA-templated transcription, regulation of DNA repair, regulation of DNA-templated tran... |
Does Knockout of Psmd4 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 579 | Knockout | Psmd4 | cell proliferation | Embryonic Stem Cell Line | Gene: Psmd4 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: identical protein binding, molecular adaptor activity, polyubiquitin modification-dependent protein binding; CC: cytosol, nucleoplasm, nucleus, proteas... |
Does Knockout of Psmb8 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,273 | Knockout | Psmb8 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Psmb8 (proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: antigen processing and presentation, cell differentiation, fat cell differentiation, immune system process, proteasome-me... |
Does Knockout of Tcp11l1 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Tcp11l1 | protein/peptide distribution | myoblast cell line | Gene: Tcp11l1 (t-complex 11 like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: microtubule
Pathways:
UniProt: Q8BTG3
Entrez ID: 320554 |
Does Knockout of Slmap in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 161 | Knockout | Slmap | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Slmap (sarcolemma associated protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: hippo signaling, negative regulation of hippo signaling, protein localization to plasma membrane, regulation of membrane depolarization during cardiac muscle cell action potential,... |
Does Knockout of Itgb1 in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Itgb1 | cell viability | Immortal mouse chromaffin cells | Gene: Itgb1 (integrin beta 1 (fibronectin receptor beta))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CD40 signaling pathway, G1/S transition of mitotic cell cycle, angiogenesis, axon extension, basement membrane organization, bicellular tight junction assembly, calci... |
Does Knockout of Ash2l in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,267 | Knockout | Ash2l | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Ash2l (ASH2 like histone lysine methyltransferase complex subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, chromatin organization, positive regulation of cell population proliferation, positive regulation of macromolecule biosynthetic pr... |
Does Knockout of G3bp1 in Melanoma Cell Line causally result in tumorigenicity? | 0 | 615 | Knockout | G3bp1 | tumorigenicity | Melanoma Cell Line | Gene: G3bp1 (G3BP stress granule assembly factor 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: defense response to virus, immune system process, innate immune response, negative regulation of canonical Wnt signaling pathway, positive regulation of type I interferon p... |
Does Knockout of Fzd6 in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Fzd6 | cell viability | Immortal mouse chromaffin cells | Gene: Fzd6 (frizzled class receptor 6)
Type: protein-coding
Summary: Enables Wnt-protein binding activity. Acts upstream of or within several processes, including cell proliferation in midbrain; embryonic morphogenesis; and establishment of body hair planar orientation. Located in apical plasma membrane... |
Does Knockout of Muc2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,174 | Knockout | Muc2 | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Muc2 (mucin 2)
Type: protein-coding
Summary: An extracellular matrix structural constituent. Involved in host-mediated regulation of intestinal microbiota composition; maintenance of gastrointestinal epithelium; and mucus secretion. Acts upstream of or within several processes, including epithelia... |
Does Knockout of Pcdha8 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,270 | Knockout | Pcdha8 | cell proliferation | Melanoma Cell Line | Gene: Pcdha8 (protocadherin alpha 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell adhesion, heart development, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding, molecular_function; CC: membran... |
Does Knockout of Anapc10 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Anapc10 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Anapc10 (anaphase promoting complex subunit 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: anaphase-promoting complex-dependent catabolic process, cell division, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein branched polyubiquiti... |
Does Knockout of Dld in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Dld | protein/peptide distribution | myoblast cell line | Gene: Dld (dihydrolipoamide dehydrogenase)
Type: protein-coding
Summary: This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In... |
Does Knockout of Vmn1r198 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 161 | Knockout | Vmn1r198 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Vmn1r198 (vomeronasal 1 receptor 198)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon... |
Does Knockout of Vcan in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Vcan | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Vcan (versican)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell adhesion, central nervous system development, glial cell migration, heart development, skeletal system development, system development, ureteric bud development; MF: calcium ion binding, carbohydra... |
Does Knockout of Atxn7l2 in Mouse cell causally result in protein/peptide accumulation? | 0 | 1,047 | Knockout | Atxn7l2 | protein/peptide accumulation | Mouse cell | Gene: Atxn7l2 (ataxin 7-like 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: B7ZCC3, Q8C8K6, B7ZCC4, A2AE44
Entrez ID: 72522 |
Does Knockout of Psen2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Psen2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Psen2 (presenilin 2)
Type: protein-coding
Summary: This gene encodes a member of the presenilin family. Presenilins are catalytic components of the multi-subunit gamma-secretase complex, which mediates critical cellular processes through cleavage of type I transmembrane proteins including Notch re... |
Does Knockout of Nudt21 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Nudt21 | cell proliferation | Melanoma Cell Line | Gene: Nudt21 (nudix hydrolase 21)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, mRNA 3'-end processing, mRNA alternative polyadenylation, mRNA processing, positive reg... |
Does Knockout of Kmt5b in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Kmt5b | protein/peptide distribution | myoblast cell line | Gene: Kmt5b (lysine methyltransferase 5B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA repair, chromatin organization, chromatin remodeling, methylation, muscle organ development, positive regulation of double-strand break repair via nonhomologous end joining, posi... |
Does Knockout of Phospho1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 165 | Knockout | Phospho1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Phospho1 (phosphatase, orphan 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: bone mineralization, bone mineralization involved in bone maturation, endochondral ossification, regulation of bone mineralization; MF: hydrolase activity, metal ion binding, phosphatas... |
Does Knockout of Slf1 in Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,528 | Knockout | Slf1 | response to chemicals | Lymphoma Cell Line | Gene: Slf1 (SMC5-SMC6 complex localization factor 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, positive regulation of double-strand break repair, positive regulation of maintenance of mitotic sister chromatid cohesion, positive regul... |
Does Knockout of Ern2 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,682 | Knockout | Ern2 | protein/peptide distribution | myoblast cell line | Gene: Ern2 (endoplasmic reticulum to nucleus signalling 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: IRE1-mediated unfolded protein response, apoptotic chromosome condensation, apoptotic process, endoplasmic reticulum unfolded protein response, intrinsic apoptotic s... |
Does Knockout of Hsd17b12 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Hsd17b12 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: estrogen biosynthetic process, extracellular matrix organization, fatty acid biosynthetic process, fatty acid elongation, saturated fatty acid, lipid metabolic proce... |
Does Knockout of Gpam in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,273 | Knockout | Gpam | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Gpam (glycerol-3-phosphate acyltransferase, mitochondrial)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CDP-diacylglycerol biosynthetic process, acyl-CoA metabolic process, cellular response to insulin stimulus, defense response to virus, diacylglycerol biosynthe... |
Does Knockout of Asb1 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,152 | Knockout | Asb1 | protein/peptide accumulation | Embryonic Cell Line | Gene: Asb1 (ankyrin repeat and SOCS box-containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular signal transduction, male genitalia development, proteasome-mediated ubiquitin-dependent protein catabolic process, protein ubiquitination; MF: ubiquitin pr... |
Does Knockout of Kmt2a in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Kmt2a | cell viability | Immortal mouse chromaffin cells | Gene: Kmt2a (lysine (K)-specific methyltransferase 2A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: T-helper 2 cell differentiation, anterior/posterior pattern specification, cellular response to transforming growth factor beta stimulus, chromatin organization, circadi... |
Does Knockout of N6amt1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 2,176 | Knockout | N6amt1 | cell proliferation | Colonic Cancer Cell Line | Gene: N6amt1 (N-6 adenine-specific DNA methyltransferase 1 (putative))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: arsonoacetate metabolic process, chromatin organization, methylation, negative regulation of gene expression, epigenetic, peptidyl-glutamine methylation,... |
Does Knockout of Pard6a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 165 | Knockout | Pard6a | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Pard6a (par-6 family cell polarity regulator alpha)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, cell-cell junction maintenance, centrosome cycle, establishment of cell polarity, establishment or maintenance of cell polarity, establishment or maint... |
Does Knockout of Ccdc126 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,684 | Knockout | Ccdc126 | protein/peptide distribution | myoblast cell line | Gene: Ccdc126 (coiled-coil domain containing 126)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q8BIS8
Entrez ID: 57895 |
Does Knockout of Ldb1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,682 | Knockout | Ldb1 | protein/peptide distribution | myoblast cell line | Gene: Ldb1 (LIM domain binding 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Wnt signaling pathway, anterior/posterior axis specification, cerebellar Purkinje cell differentiation, cerebellum development, epithelial structure maintenance, gastrulation with mouth form... |
Does Knockout of Lztfl1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 161 | Knockout | Lztfl1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Lztfl1 (leucine zipper transcription factor-like 1)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity. Acts upstream of or within flagellated sperm motility and spermatogenesis. Located in cilium; cytoplasm; and manchette. Is expressed in several structures, incl... |
Does Knockout of Klk8 in Embryonic Fibroblast Cell Line causally result in response to virus? | 1 | 1,133 | Knockout | Klk8 | response to virus | Embryonic Fibroblast Cell Line | Gene: Klk8 (kallikrein related-peptidase 8)
Type: protein-coding
Summary: This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity an... |
Does Knockout of Ppa1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Ppa1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Ppa1 (pyrophosphatase (inorganic) 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: phosphate-containing compound metabolic process; MF: hydrolase activity, inorganic diphosphate phosphatase activity, magnesium ion binding, metal ion binding, pyrophosphatase activi... |
Does Knockout of Supt3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 165 | Knockout | Supt3 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Supt3 (SPT3, SAGA and STAGA complex component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, transcription by RNA polymerase II; MF: protein heterodimerization ac... |
Does Knockout of Etnk2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 165 | Knockout | Etnk2 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Etnk2 (ethanolamine kinase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: glycerophospholipid biosynthetic process, in utero embryonic development, lipid metabolic process, multicellular organism growth, phosphatidylethanolamine biosynthetic process, phospholipi... |
Does Knockout of Arih1 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,265 | Knockout | Arih1 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Arih1 (ariadne RBR E3 ubiquitin protein ligase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein ubiquitination, ubiquitin-dependent protein catabolic process; MF: metal ion binding, transferase activity, ubiquitin conjugating enzyme binding, ubiquitin prot... |
Does Knockout of Zdhhc2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,171 | Knockout | Zdhhc2 | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Zdhhc2 (zinc finger, DHHC domain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: peptidyl-L-cysteine S-palmitoylation, positive regulation of AMPA glutamate receptor clustering, positive regulation of endosome to plasma membrane protein transport, posi... |
Does Knockout of Zfp868 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Zfp868 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Zfp868 (zinc finger protein 868)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ... |
Does Knockout of Mettl3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Mettl3 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Mettl3 (methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, RNA methylation, cell differentiation, cellular response to UV, circadian rhythm, dosage compensation by inact... |
Does Knockout of Thnsl1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,275 | Knockout | Thnsl1 | cell proliferation | Colonic Cancer Cell Line | Gene: Thnsl1 (threonine synthase-like 1 (bacterial))
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q8BH55
Entrez ID: 208967 |
Does Knockout of Zfp358 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Zfp358 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Zfp358 (zinc finger protein 358)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription activator activity, RNA polymeras... |
Does Knockout of Cand1 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,264 | Knockout | Cand1 | cell proliferation | Colonic Cancer Cell Line | Gene: Cand1 (cullin associated and neddylation disassociated 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: SCF complex assembly, cell differentiation, negative regulation of catalytic activity, positive regulation of DNA-templated transcription, positive regulation o... |
Does Knockout of Mblac2 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,265 | Knockout | Mblac2 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Mblac2 (metallo-beta-lactamase domain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, fatty acid metabolic process, lipid metabolic process; MF: beta-lactamase activity, hydrolase activity, long-chain fatty acyl-CoA hydrolase activi... |
Does Knockout of Rabep1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Rabep1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Rabep1 (rabaptin, RAB GTPase binding effector protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Golgi to plasma membrane transport, apoptotic process, endocytosis, protein localization to ciliary membrane, protein transport, regulation of postsynaptic neuro... |
Does Knockout of Mpnd in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,271 | Knockout | Mpnd | cell proliferation | Mouse kidney carcinoma cell | Gene: Mpnd (MPN domain containing)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: double-strand break repair, proteolysis; MF: hydrolase activity, metal ion binding, metallopeptidase activity, peptidase activity, polyubiquitin modification-dependent protein binding; CC: ... |
Does Knockout of Dctn5 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Dctn5 | cell proliferation | Melanoma Cell Line | Gene: Dctn5 (dynactin 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aorta development, coronary vasculature development, ventricular septum development; CC: centrosome, chromosome, chromosome, centromeric region, cytoplasm, cytoskeleton, dynactin complex, kinetochore... |
Does Knockout of Rorc in Embryonic Fibroblast Cell Line causally result in autophagy? | 1 | 1,043 | Knockout | Rorc | autophagy | Embryonic Fibroblast Cell Line | Gene: Rorc (RAR-related orphan receptor gamma)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Peyer's patch development, T cell differentiation in thymus, T-helper 17 cell differentiation, T-helper cell differentiation, adipose tissue development, alpha-beta T cell diffe... |
Does Knockout of Skor2 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Skor2 | protein/peptide distribution | myoblast cell line | Gene: Skor2 (SKI family transcriptional corepressor 2)
Type: protein-coding
Summary: Enables SMAD binding activity; chromatin binding activity; and histone deacetylase binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, i... |
Does Knockout of Entpd7 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,679 | Knockout | Entpd7 | protein/peptide distribution | myoblast cell line | Gene: Entpd7 (ectonucleoside triphosphate diphosphohydrolase 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CTP catabolic process, CTP metabolic process, GTP metabolic process, T-helper 17 cell differentiation, UDP catabolic process, UTP catabolic process, nucleobase-... |
Does Knockout of Smarca4 in Pancreatic Cell Line causally result in protein/peptide accumulation? | 1 | 2,198 | Knockout | Smarca4 | protein/peptide accumulation | Pancreatic Cell Line | Gene: Smarca4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aorta development, aortic smooth muscle cell differentiation, blastocyst growth, blastocyst hatching, blood ve... |
Does Knockout of Ncoa1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,287 | Knockout | Ncoa1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Ncoa1 (nuclear receptor coactivator 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to Thyroglobulin triiodothyronine, cellular response to hormone stimulus, cerebellum development, cerebral cortex development, chromatin remodeling, estrogen rec... |
Does Knockout of Cul4a in Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,527 | Knockout | Cul4a | response to chemicals | Lymphoma Cell Line | Gene: Cul4a (cullin 4A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, T cell activation, base-excision repair, AP site formation via deaminated base removal, cellular response to UV, developmental process, hemopoiesis, in utero embryonic... |
Does Knockout of Fam98b in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,265 | Knockout | Fam98b | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Fam98b (family with sequence similarity 98, member B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of cell population proliferation, positive regulation of gene expression, protein methylation; MF: identical protein binding, protein methyltran... |
Does Knockout of Hdhd5 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,264 | Knockout | Hdhd5 | cell proliferation | Colonic Cancer Cell Line | Gene: Hdhd5 (haloacid dehalogenase like hydrolase domain containing 5)
Type: protein-coding
Summary: Predicted to be involved in glycerophospholipid biosynthetic process. Located in mitochondrion. Is expressed in brain. Orthologous to human HDHD5 (haloacid dehalogenase like hydrolase domain containing 5... |
Does Knockout of Sostdc1 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 2,477 | Knockout | Sostdc1 | cell proliferation | Embryonic Stem Cell Line | Gene: Sostdc1 (sclerostin domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: BMP signaling pathway, Wnt signaling pathway, epithelial cell fate commitment, hair follicle morphogenesis, mammary gland bud morphogenesis, negative regulation of BMP signaling... |
Does Knockout of Lasp1 in macrophage causally result in phagocytosis? | 0 | 1,888 | Knockout | Lasp1 | phagocytosis | macrophage | Gene: Lasp1 (LIM and SH3 protein 1)
Type: protein-coding
Summary: Enables actin filament binding activity. Predicted to be involved in monoatomic ion transport. Located in cytoplasm and focal adhesion. Is expressed in several structures, including alimentary system; bone; central nervous system; genitou... |
Does Knockout of Sil1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,682 | Knockout | Sil1 | protein/peptide distribution | myoblast cell line | Gene: Sil1 (SIL1 nucleotide exchange factor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: adenyl-nucleotide exchange factor activity, identical protein binding; CC: endoplasmic reticulum, endoplasmic reticulum lumen
Pathways: Protein processing in endoplasmic ... |
Does Knockout of Mast1 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,275 | Knockout | Mast1 | cell proliferation | Colonic Cancer Cell Line | Gene: Mast1 (microtubule associated serine/threonine kinase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: brain development, cytoskeleton organization, developmental process, intracellular signal transduction, protein phosphorylation; MF: ATP binding, kinase activity... |
Does Knockout of Defa30 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Defa30 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Defa30 (defensin, alpha, 30)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response, defense response to Gram-negative bacterium, defense response to G... |
Does Knockout of Gm14744 in macrophage causally result in phagocytosis? | 0 | 1,888 | Knockout | Gm14744 | phagocytosis | macrophage | Gene: Gm14744 (predicted gene 14744)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: molecular_function, odorant binding, pheromone binding, small molecule binding; CC: extracellular region, extracellular space
Pathways:
UniProt: B1AVU4
Entrez I... |
Does Knockout of Lrch2 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,270 | Knockout | Lrch2 | cell proliferation | Melanoma Cell Line | Gene: Lrch2 (leucine-rich repeats and calponin homology (CH) domain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q3UMG5
Entrez ID: 210297 |
Does Knockout of Tmod2 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,152 | Knockout | Tmod2 | protein/peptide accumulation | Embryonic Cell Line | Gene: Tmod2 (tropomodulin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin filament organization, learning or memory, muscle contraction, myofibril assembly, neuron-neuron synaptic transmission, pointed-end actin filament capping, positive regulation of G protein-... |
Does Knockout of Cldn20 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,273 | Knockout | Cldn20 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Cldn20 (claudin 20)
Type: protein-coding
Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the para... |
Does Knockout of Map3k14 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 165 | Knockout | Map3k14 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Map3k14 (mitogen-activated protein kinase kinase kinase 14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: MAPK cascade, cellular response to mechanical stimulus, defense response to virus, immune response, non-canonical NF-kappaB signal transduction; MF: ATP bindi... |
Does Knockout of Tulp1 in macrophage causally result in phagocytosis? | 0 | 1,888 | Knockout | Tulp1 | phagocytosis | macrophage | Gene: Tulp1 (TUB like protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: dendrite development, detection of light stimulus involved in visual perception, eye photoreceptor cell development, phagocytosis, phagocytosis, recognition, photoreceptor cell maintenance, p... |
Does Knockout of Riok1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Riok1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Riok1 (RIO kinase 1)
Type: protein-coding
Summary: This gene encodes a member of the RIO family of atypical serine protein kinases. A similar protein in humans is a component of the protein arginine methyltransferase 5 complex that specifically recruits the RNA-binding protein nucleolin as a methy... |
Does Knockout of Vmn2r110 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,270 | Knockout | Vmn2r110 | cell proliferation | Melanoma Cell Line | Gene: Vmn2r110 (vomeronasal 2, receptor 110)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane
Pathways:
UniProt: A0A... |
Does Knockout of Anp32a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Anp32a | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Anp32a (acidic nuclear phosphoprotein 32 family member A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of plasma membrane bounded cell projection assembly, nucleocytoplasmic transport, regulation of apoptotic process; MF: cell adhesion molecul... |
Does Knockout of Ewsr1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Ewsr1 | protein/peptide distribution | myoblast cell line | Gene: Ewsr1 (Ewing sarcoma breakpoint region 1)
Type: protein-coding
Summary: Predicted to enable RNA binding activity; identical protein binding activity; and transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Located in nucleus. Is expressed in s... |
Does Knockout of Kmt2d in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 1,130 | Knockout | Kmt2d | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Kmt2d (lysine (K)-specific methyltransferase 2D)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, developmental growth, heterochromatin formation, in utero embryonic development, methylation, oocyte growth, oogenesis, positive regulation of ce... |
Does Knockout of Scn1b in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,262 | Knockout | Scn1b | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Scn1b (sodium channel, voltage-gated, type I, beta)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axon guidance, cardiac conduction, cardiac muscle cell action potential involved in contraction, cardiac muscle contraction, corticospinal neuron axon guidance, locom... |
Does Knockout of Slc16a4 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,682 | Knockout | Slc16a4 | protein/peptide distribution | myoblast cell line | Gene: Slc16a4 (solute carrier family 16 (monocarboxylic acid transporters), member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: carboxylic acid transmembrane transport, monocarboxylic acid transport, transmembrane transport; MF: monocarboxylic acid transmembrane tra... |
Does Knockout of Dennd1c in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 578 | Knockout | Dennd1c | cell proliferation | Embryonic Stem Cell Line | Gene: Dennd1c (DENN domain containing 1C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: endocytic recycling, endocytosis; MF: guanyl-nucleotide exchange factor activity, phosphatidylinositol phosphate binding, small GTPase binding; CC: centrosome, clathrin-coated vesicl... |
Does Knockout of Tdpoz4 in Melanoma Cell Line causally result in cell proliferation? | 0 | 2,492 | Knockout | Tdpoz4 | cell proliferation | Melanoma Cell Line | Gene: Tdpoz4 (TD and POZ domain containing 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, protein catabolic process, protein polyubiquitination, regulation of proteolysis; MF: identical protein binding... |
Does Knockout of Dnajc19 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Dnajc19 | protein/peptide distribution | myoblast cell line | Gene: Dnajc19 (DnaJ heat shock protein family (Hsp40) member C19)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: genitalia development, protein import into mitochondrial matrix, protein transport, regulation of cardiolipin metabolic process, visual perception; MF: ATPase... |
Does Knockout of Pcyt1a in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,264 | Knockout | Pcyt1a | cell proliferation | Colonic Cancer Cell Line | Gene: Pcyt1a (phosphate cytidylyltransferase 1, choline, alpha isoform)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell proliferation, CDP-choline pathway, isotype switching, lipid metabolic process, phosphatidylcholine biosynthetic process, phospholipid biosynthet... |
Does Knockout of Pde4a in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,682 | Knockout | Pde4a | protein/peptide distribution | myoblast cell line | Gene: Pde4a (phosphodiesterase 4A, cAMP specific)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cAMP catabolic process, cellular response to xenobiotic stimulus, modulation of chemical synaptic transmission, negative regulation of cAMP/PKA signal transduction, regulatio... |
Does Knockout of Srp68 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Srp68 | cell proliferation | Embryonic Stem Cell Line | Gene: Srp68 (signal recognition particle 68)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: SRP-dependent cotranslational protein targeting to membrane, response to xenobiotic stimulus; MF: 7S RNA binding, RNA binding, endoplasmic reticulum signal peptide binding, protei... |
Does Knockout of Pold2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Pold2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Pold2 (polymerase (DNA directed), delta 2, regulatory subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA biosynthetic process, DNA damage response, DNA metabolic process, DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA-t... |
Does Knockout of Pcnx3 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,288 | Knockout | Pcnx3 | cell proliferation | Mouse kidney carcinoma cell | Gene: Pcnx3 (pecanex homolog 3)
Type: protein-coding
Summary: Predicted to be located in membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system. Orthologous to human PCNX3 (pecanex 3). [provided by Alliance of... |
Does Knockout of Farsb in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Farsb | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Farsb (phenylalanyl-tRNA synthetase, beta subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: phenylalanyl-tRNA aminoacylation, protein heterotetramerization, translation; MF: ATP binding, RNA binding, aminoacyl-tRNA ligase activity, ligase activity, magnesium ... |
Does Knockout of Syp in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,684 | Knockout | Syp | protein/peptide distribution | myoblast cell line | Gene: Syp (synaptophysin)
Type: protein-coding
Summary: Enables SH2 domain binding activity and identical protein binding activity. Involved in regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity; and regulation of synaptic vesicle priming. Located... |
Does Knockout of Mmel1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,275 | Knockout | Mmel1 | cell proliferation | Colonic Cancer Cell Line | Gene: Mmel1 (membrane metallo-endopeptidase-like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein processing, proteolysis; MF: endopeptidase activity, hydrolase activity, metal ion binding, metalloendopeptidase activity, metallopeptidase activity, peptidase acti... |
Does Knockout of Slc24a5 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,289 | Knockout | Slc24a5 | cell proliferation | Mouse kidney carcinoma cell | Gene: Slc24a5 (solute carrier family 24, member 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: calcium ion import, calcium ion transmembrane transport, calcium ion transport, intracellular calcium ion homeostasis, monoatomic ion transmembrane transport, monoatomic ion... |
Does Knockout of Ung in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,440 | Knockout | Ung | protein/peptide accumulation | Embryonic Cell Line | Gene: Ung (uracil DNA glycosylase)
Type: protein-coding
Summary: Enables uracil DNA N-glycosylase activity. Acts upstream of or within isotype switching and somatic hypermutation of immunoglobulin genes. Located in mitochondrion and nucleus. Is expressed in several structures, including alimentary syste... |
Does Knockout of Tirap in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 2,403 | Knockout | Tirap | protein/peptide accumulation | Embryonic Cell Line | Gene: Tirap (toll-interleukin 1 receptor (TIR) domain-containing adaptor protein)
Type: protein-coding
Summary: Enables several functions, including Toll-like receptor 2 binding activity; identical protein binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several ... |
Does Knockout of Glrx5 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 579 | Knockout | Glrx5 | cell proliferation | Embryonic Stem Cell Line | Gene: Glrx5 (glutaredoxin 5)
Type: protein-coding
Summary: This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in the human gene are associated with autosomal rec... |
Does Knockout of Etfdh in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Etfdh | protein/peptide distribution | myoblast cell line | Gene: Etfdh (electron transferring flavoprotein, dehydrogenase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: electron transport chain, fatty acid beta-oxidation using acyl-CoA dehydrogenase, respiratory electron transport chain, response to oxidative stress; MF: 4 iron... |
Does Knockout of Impdh2 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Impdh2 | cell proliferation | Embryonic Stem Cell Line | Gene: Impdh2 (inosine monophosphate dehydrogenase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' XMP biosynthetic process, GMP biosynthetic process, GMP salvage, GTP biosynthetic process, cellular response to interleukin-4, circadian rhythm, lymphocyte proli... |
Does Knockout of Ppp1r3c in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 579 | Knockout | Ppp1r3c | cell proliferation | Embryonic Stem Cell Line | Gene: Ppp1r3c (protein phosphatase 1, regulatory subunit 3C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: glycogen biosynthetic process, glycogen metabolic process, protein targeting, regulation of glycogen biosynthetic process, regulation of glycogen catabolic process... |
Does Knockout of Fbxo5 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 684 | Knockout | Fbxo5 | cell proliferation | Acute Myeloid Leukemia Cell Line | Gene: Fbxo5 (F-box protein 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, cell division, meiotic nuclear division, microtubule polymerization, negative regulation of DNA endoreduplication, negative regulation of cellular senescence, negative regul... |
Does Knockout of Pgls in macrophage causally result in phagocytosis? | 0 | 1,888 | Knockout | Pgls | phagocytosis | macrophage | Gene: Pgls (6-phosphogluconolactonase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: carbohydrate metabolic process, pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch; MF: 6-phosphogluconolactonase activity, hydrolase activity, monosaccharide binding; C... |
Does Knockout of Arhgap9 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,679 | Knockout | Arhgap9 | protein/peptide distribution | myoblast cell line | Gene: Arhgap9 (Rho GTPase activating protein 9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: signal transduction, small GTPase-mediated signal transduction; MF: GTPase activator activity, phosphatidylinositol-3,4,5-trisphosphate binding; CC: cytoplasm, plasma membrane
... |
Does Knockout of Tph1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 83 | Knockout | Tph1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Tph1 (tryptophan hydroxylase 1)
Type: protein-coding
Summary: This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase family. The encoded protein is one of two tryptophan hydroxylase enzymes that catalyze the first and rate limiting step in the biosynthesis of the hor... |
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