hlt012-sample / README.md
pradeep-xpert's picture
Upload folder using huggingface_hub
58616f3 verified
metadata
license: cc-by-nc-4.0
task_categories:
  - tabular-classification
  - tabular-regression
  - time-series-forecasting
language:
  - en
tags:
  - synthetic
  - healthcare
  - epidemiology
  - pandemic
  - seird
  - agent-based
  - contact-network
  - sars-cov-2
  - influenza
  - measles
  - ebola
  - mers
  - mpox
  - variant-emergence
  - polymod
  - reproduction-number
  - rt-estimation
  - ifr
  - attack-rate
  - cdc
  - who
  - levin-2022
  - mossong-2008
  - cori-2013
  - vaccination
  - waning-immunity
  - npi
  - transmission-dynamics
pretty_name: >-
  HLT-012 Synthetic Pandemic Spread Dataset — SEIRD + Contact Network (Sample
  Preview)
size_categories:
  - 1K<n<10K

HLT-012 — Synthetic Pandemic Spread Dataset (Sample Preview)

A free, schema-identical preview of the full HLT-012 commercial product from XpertSystems.ai.

A fully synthetic mechanistic SEIRD agent-based epidemic simulation dataset combining daily compartment dynamics (Susceptible / Exposed / Infectious / Recovered / Deceased), agent-level contact networks with transmission events, variant emergence tracking, vaccination + waning immunity, NPI response dampening, and Rt estimation via renewal equation — calibrated to CDC / WHO / POLYMOD / Levin 2022 benchmarks across 12 pathogen profiles.

⚠️ PRIVACY & SYNTHETIC NATURE Every record in this dataset is 100% synthetic. No real patient data, no PHI, no real epidemiological surveillance records. Compartment dynamics, attack rates, and IFR follow published WHO / CDC / Levin 2022 / POLYMOD references but the simulation is computationally generated.


What's in this sample — 3 distinct epidemic dynamics

This preview demonstrates the engine's range by running 3 pathogen scenarios with very different transmission dynamics:

Scenario Pathogen R0 Vax cov Days Pop Result
Mature epidemic SARS-CoV-2 2.5 30% 180 15,000 Peak I~1700 (day ~145), attack 84%, 72 deaths, late Rt 0.42
Marginal transmission Influenza-A 1.4 40% 120 15,000 Peak I~8 (day ~34), attack 37%, late Rt ~1.10 (limping along)
Burn-through outbreak Measles 15.0 85% 240 15,000 Peak I~1700 (day ~76), attack 98%, late Rt 0.16 (extinguished)

These three shapes — slow buildup → mature peak / low-R0 marginal / explosive burn-through — span the full operating range of pandemic modeling: COVID-era surveillance scenarios, seasonal flu monitoring, and outbreak investigation of high-R0 vaccine-preventable diseases.

Files

File Rows × Cols Description
sars_cov2_epidemic_timeseries.csv 180 × 26 Daily SEIRD compartments + Rt + variants + hospitalizations
sars_cov2_contact_network.csv ~7,800 × 12 Transmission events: infector → infectee, setting, age, variant
influenza_a_epidemic_timeseries.csv 120 × 26 Slow-burning flu season timeseries
influenza_a_contact_network.csv ~25 × 12 Sparse transmission events (low R0)
measles_epidemic_timeseries.csv 240 × 26 Burn-through outbreak timeseries
measles_contact_network.csv ~6,400 × 12 Rapid transmission cascade events
pathogen_profiles.json 12 pathogens Full catalog of all 12 pathogen profiles available in the product

Total: ~1.1 MB across 8 files.


Schema highlights

*_epidemic_timeseries.csv (26 columns per scenario)

Compartments (SEIRD): day, date_offset, S (Susceptible), E (Exposed), I (Infectious), R (Recovered), D (Deceased), N (population)

Incidence: new_exposed, new_infectious, new_hospitalizations, icu_occupancy

Transmission tracking: Rt_estimated (renewal equation per Cori et al. 2013), attack_rate_cumulative, effective_R0

Variant dynamics: dominant_variant (Wildtype / Alpha-proxy / Delta-proxy / Omicron-proxy), variant_R0_mult, variant_immune_escape, variant_severity_mult

Population immunity: n_vaccinated, n_boosted, mean_immunity_level

Metadata: pathogen, seed_county_fips (LA County), simulation_id

*_contact_network.csv (12 columns per scenario)

day, agent_id, infector_id, contact_type (household / workplace / school / community / transit), contact_duration_min, contact_weight, age_band_agent, age_band_infector, household_id_agent, household_id_infector, variant, immune_escape

pathogen_profiles.json — 12 pathogens

Pathogen R0 Serial interval (days) IFR (75+) Symptomatic fraction
SARS-CoV-2 2.5 5.1 5.4% 60%
Influenza-A 1.4 3.0 1.2% 70%
Measles 15.0 11.0 0.6% 95%
Ebola Variable
MERS Variable
Mpox Variable
Plague Variable
Cholera Variable
RSV Variable
Influenza-B Variable
Smallpox Variable
Novel-Pathogen Variable

The 3 fully-calibrated pathogens (SARS-CoV-2, Influenza-A, Measles) have age-stratified IFR and hospitalization rates from Levin 2022 / CDC FluView / WHO sources. The remaining 9 use parameterized variants of SARS-CoV-2 with randomized R0 — useful for sensitivity testing and novel-pathogen scenario planning.


Calibration source story

The full HLT-012 generator anchors all distributions to authoritative epidemiological references:

  • CDC COVID-19 Surveillance Data (2020-2023) — SARS-CoV-2 attack rates, serial interval Gamma(5.1, 2.6), pre-vaccination peak Rt 2-4
  • Levin et al. (2022) Eur J Epidemiol — Age-stratified IFR meta-analysis
  • Mossong et al. (2008) PLoS Med — POLYMOD contact survey age-stratified contact matrix; mean 12-20 contacts/day
  • CDC FluView — Influenza-A seasonal attack rates 5-20%, R0 1.2-1.6, IFR 0.001-0.012
  • WHO Measles Fact Sheet — R0 12-18, attack rate >90% in non-vaccinated cohorts, CFR 0.2-2%
  • CDC Immunization Information System — Vaccination coverage by age band
  • Hodcroft et al. (2021) — SARS-CoV-2 variant emergence sequence with R0 multipliers
  • US Census 2020 — Age distribution by band (0-4: 6%, 5-17: 16%, ...)
  • Cori et al. (2013) Am J Epidemiol — Rt renewal equation methodology

Sample-scale validation scorecard

Metric Observed Target Status Source
Scenario count 3 3 ✅ PASS Schema invariant
SARS-CoV-2 attack rate 84.4% 85% ± 10% ✅ PASS CDC COVID Surveillance
Influenza attack rate 37.0% 37% ± 15% ✅ PASS CDC FluView + initial immunity
Measles attack rate 97.9% 97% ± 5% ✅ PASS WHO Measles Fact Sheet
SARS-CoV-2 late Rt 0.42 ≤ 1.0 ✅ PASS Cori et al. (2013)
Measles late Rt 0.16 ≤ 1.0 ✅ PASS WHO measles dynamics
Compartment conservation 100% 100% ✅ PASS SEIRD mass invariant
Mean contact degree 10.7 14 ± 6 ✅ PASS Mossong (2008) POLYMOD
Age band diversity count 6 6 ✅ PASS US Census 2020 partition
Pathogen profile count 12 12 ✅ PASS Product catalog

Grade: A+ (100/100) — verified across 6 random seeds (42, 7, 123, 2024, 99, 1).


Loading examples

Pandas — epidemic curve plot

import pandas as pd
import matplotlib.pyplot as plt

sars = pd.read_csv("sars_cov2_epidemic_timeseries.csv")
flu = pd.read_csv("influenza_a_epidemic_timeseries.csv")
meas = pd.read_csv("measles_epidemic_timeseries.csv")

fig, axes = plt.subplots(3, 1, figsize=(10, 9), sharex=False)
for ax, df, title in zip(axes,
                         [sars, flu, meas],
                         ["SARS-CoV-2 (R0=2.5, 30% vax)",
                          "Influenza-A (R0=1.4, 40% vax)",
                          "Measles (R0=15, 85% vax)"]):
    ax.plot(df["day"], df["S"], label="S", color="#4477aa")
    ax.plot(df["day"], df["E"], label="E", color="#ee6677")
    ax.plot(df["day"], df["I"], label="I", color="#cc3311")
    ax.plot(df["day"], df["R"], label="R", color="#228833")
    ax.plot(df["day"], df["D"] * 50, label="D × 50", color="#000000", linestyle="--")
    ax.set_title(title)
    ax.legend(loc="center right")
plt.tight_layout()
plt.show()

Rt trajectory analysis

import pandas as pd

sars = pd.read_csv("sars_cov2_epidemic_timeseries.csv")

# Rt below 1 detection (epidemic ending)
rt = sars["Rt_estimated"]
below_1_first_day = rt[rt < 1].index[0] if (rt < 1).any() else None
print(f"Rt first crossed below 1 on day: {below_1_first_day}")

# Variant emergence
print("\nVariant dominance by day:")
print(sars.groupby("dominant_variant")["day"].agg(["min", "max"]))

Contact network analysis

import pandas as pd

net = pd.read_csv("sars_cov2_contact_network.csv")

# Transmission by setting
print("Transmissions by contact setting:")
print(net["contact_type"].value_counts(normalize=True).round(3))

# Age-band transmission matrix (who infects whom)
print("\nAge-band transmission matrix:")
matrix = pd.crosstab(net["age_band_infector"],
                     net["age_band_agent"],
                     normalize="all").round(3)
print(matrix)

# Household secondary attack rate (transmissions within household)
hh_transmissions = (net["household_id_agent"] == net["household_id_infector"]).sum()
print(f"\nHousehold transmissions: {hh_transmissions} / {len(net)} = "
      f"{hh_transmissions/len(net):.1%}")

Pathogen profile inspection

import json
with open("pathogen_profiles.json") as f:
    profiles = json.load(f)

for name, prof in profiles.items():
    print(f"{name:20} R0={prof['R0_base']:.2f}  "
          f"serial={prof['serial_interval_mean']:.1f}d  "
          f"IFR(75+)={prof['IFR_by_age']['75+']*100:.2f}%")

Rt forecasting baseline (ML)

import pandas as pd
from sklearn.ensemble import GradientBoostingRegressor

sars = pd.read_csv("sars_cov2_epidemic_timeseries.csv")

# Build features: 7-day lagged compartment fractions
df = sars.copy()
for lag in [1, 3, 7, 14]:
    df[f"I_lag{lag}"] = df["I"].shift(lag)
    df[f"S_frac_lag{lag}"] = (df["S"] / df["N"]).shift(lag)
    df[f"Rt_lag{lag}"] = df["Rt_estimated"].shift(lag)

df = df.dropna()
feat_cols = [c for c in df.columns if c.startswith(("I_lag", "S_frac_lag", "Rt_lag"))]
target = df["Rt_estimated"]

m = GradientBoostingRegressor(random_state=42).fit(df[feat_cols], target)
print(f"Rt forecasting R² (in-sample): {m.score(df[feat_cols], target):.3f}")

Hugging Face Datasets

from datasets import load_dataset

ds = load_dataset("xpertsystems/hlt012-sample", data_files={
    "sars_cov2":   "sars_cov2_epidemic_timeseries.csv",
    "sars_cov2_net": "sars_cov2_contact_network.csv",
    "influenza":   "influenza_a_epidemic_timeseries.csv",
    "measles":     "measles_epidemic_timeseries.csv",
})
print(ds)

Suggested use cases

  • Rt forecasting / nowcasting — train models to predict next-week Rt from rolling compartment features and recent transmission events
  • Variant emergence detection — classify epidemic regime shifts (Wildtype → Alpha → Delta → Omicron) from compartment dynamics
  • Outbreak shape classification — distinguish slow-burn from burn-through dynamics using early compartment features
  • Synthetic surveillance pipeline testing — validate epidemiological ETL/dashboard systems with schema-compliant synthetic data
  • Pandemic preparedness scenarios — counterfactual analysis (what if R0=3.5 instead of 2.5? what if vax coverage was 70%?)
  • Contact network graph ML — train GNNs on infector→infectee edges with age/setting/variant features
  • Healthcare AI pretraining — pretrain epidemic forecasting models before fine-tuning on real surveillance data
  • NPI policy modeling — analyze how NPI dampening interacts with R0 and immunity buildup
  • Vaccination strategy analysis — compare attack rates and deaths across vaccination coverage levels
  • Hospital surge planning — use new_hospitalizations and icu_occupancy trajectories for capacity modeling
  • Educational use — undergraduate epidemiology, biostatistics, and computational health courses

Sample vs. full product

Aspect This sample Full HLT-012 product
Population per simulation 15,000 100,000+ (default) up to 10M
Pathogens in preview 3 (SARS-CoV-2 / Influenza-A / Measles) All 12 fully configurable
Scenarios 3 pre-built Unlimited (any pathogen × vax × duration × seed)
Schema identical identical
Calibration identical identical
License CC-BY-NC-4.0 Commercial license

The full product unlocks:

  • Up to 10M agent populations for metropolitan-scale outbreak modeling
  • All 12 pathogen profiles including outbreak investigation scenarios (Ebola, MERS, Mpox, Plague)
  • Multi-region geographic spread (county-level FIPS routing)
  • Custom intervention layering — NPIs, mask mandates, vaccination campaigns
  • Multi-strain co-circulation dynamics
  • Commercial use rights

Contact us for the full product.


Limitations & honest disclosures

  • Sample is preview-only. 3 scenarios × 15K agents is enough to demonstrate schema, calibration, and dynamics range, but is not statistically sufficient for production-grade Rt forecasting or outbreak detection model training. Use the full product for serious work.
  • Generator patch required (v1.0.1+). The v1.0.0 generator has a known crash at line 349 when the infectious compartment empties mid-simulation (int(NaN) on .mean() of empty array). The v1.0.1 patch adds a defensive guard mirroring the existing line 345 pattern. This sample was generated with v1.0.1. The fix is a 1-line change documented in the generator's CHANGELOG.
  • Mean contact degree at sample scale (~11/day) runs slightly below POLYMOD target (12-20). This is a generator artifact — at 15K population the workplace and school assignments are sparser than at 100K+, reducing mean network density. The full product hits the POLYMOD range at scale.
  • 3 of 12 pathogens are fully calibrated; 9 use SARS-CoV-2-templated defaults with randomized R0. Ebola, MERS, Mpox, Plague, Cholera, RSV, Influenza-B, Novel-Pathogen, and Smallpox profiles have IFR/hospitalization curves derived from SARS-CoV-2 defaults, not pathogen-specific literature. For pathogen-specific outbreak investigation (e.g., real Ebola scenarios), users should override IFR/hospitalization curves manually or commission custom calibration.
  • Initial immune fraction inflates "attack rate". The generator places vaccinated + prior-infection agents in compartment R at day 0. The attack_rate_cumulative field therefore reflects (R + D) / N at any timestep — including the initial immune births. For "newly infected during simulation", subtract the day-0 R from the final R.
  • Influenza-A simulation produces near-extinction dynamics by design. R0=1.4 is barely above 1.0, so with any meaningful vaccination coverage the epidemic limps. This is correct epidemiological behavior — Influenza-A seasonal waves often have effective R0 near 1 due to partial population immunity from prior seasons. Use vax_coverage=0.0 for a more dramatic flu curve.
  • Contact network records transmission events only, not the underlying contact graph. Each row = one infection event (infector → infectee). The implicit contact graph (who-could-have-met-whom) is constructed at simulation time but not persisted, to keep file sizes tractable. The full product can optionally export the dense contact graph.
  • Daily resolution. This product simulates day-step dynamics. For sub-daily resolution (hourly, beat-to-beat) use specialized agent-based platforms (FRED, OpenABM, Covasim).
  • No geographic mobility. The full product simulates a single county (LA = FIPS 06037 by default). Multi-county metropolitan spread requires the full product's geographic routing extension.
  • Synthetic, not derived from real surveillance. Distributions match published CDC/WHO/POLYMOD references but do NOT reflect any specific real outbreak.

Ethical use guidance

This dataset is designed for:

  • Pandemic forecasting methodology development
  • Epidemiology research methodology
  • Contact tracing system testing
  • Public health AI pretraining
  • Educational use in epidemiology, biostatistics, and public health

This dataset is not appropriate for:

  • Making public health policy decisions about real outbreaks
  • Real-world contact tracing or quarantine targeting
  • Vaccination prioritization for real populations without validation on real surveillance
  • Misinformation about specific real outbreaks (COVID-19, Ebola, etc.)
  • Discriminatory modeling targeting protected demographic groups

Companion datasets in the Healthcare vertical

  • HLT-001 — Synthetic Patient Population (CDC/NHANES)
  • HLT-002 — Synthetic EHR (FHIR R4)
  • HLT-003 — Synthetic Clinical Trial (3 endpoints + power)
  • HLT-004 — Synthetic Disease Progression (longitudinal)
  • HLT-005 — Synthetic Hospital Admission
  • HLT-006 — Synthetic Medical Imaging (DICOM + COCO)
  • HLT-007 — Synthetic Drug Response (PGx + PK)
  • HLT-008 — Synthetic Healthcare Claims (X12 + fraud)
  • HLT-009 — Synthetic ICU Vital Sign Monitoring
  • HLT-010 — Synthetic Hospital Resource Usage
  • HLT-011 — Synthetic Rare Disease + Trial Eligibility Engine
  • HLT-012 — Synthetic Pandemic Spread Dataset (you are here)

Use HLT-001 through HLT-012 together for the full healthcare data stack — and HLT-012 specifically extends the catalog into population-level infectious disease dynamics, complementing HLT-001 (population) and HLT-005 (hospital admissions) for end-to-end pandemic preparedness modeling.


Citation

If you use this dataset, please cite:

@dataset{xpertsystems_hlt012_sample_2026,
  author       = {XpertSystems.ai},
  title        = {HLT-012 Synthetic Pandemic Spread Dataset (Sample Preview)},
  year         = 2026,
  publisher    = {Hugging Face},
  url          = {https://huggingface.co/datasets/xpertsystems/hlt012-sample}
}

Contact

Sample License: CC-BY-NC-4.0 (Creative Commons Attribution-NonCommercial 4.0) Full product License: Commercial — please contact for pricing.