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0fd3e639-13c0-483f-bf26-d94aaf84bb17 | Actinomycetoma is caused by: | Bacteria | Virus | Fungus | Protozoa | 0a | single | Bacteria | Microbiology | null |
7e8e07ee-35d9-42fc-a7ad-616602edf5de | An important clinical feature of a concussed tooth is: | Tooth is markedly tender to percussion | Tooth is displaced from the socket | Evidence of haemorrhage at gingival margin | Clinically crown appears shorter | 0a | multi | Concussion
Tooth is not displaced.
Mobility is not present.
Tooth is tender to percussion because of edema and hemorrhage in the periodontal ligament.
Pulp may respond normal to testing. | Dental | null |
33aeb759-0e02-48f7-b681-239eaf45cdea | Which component of the eye has maximum refreactive index | Anterior surface of the lens | Posterior surface of the lens | Centre of the lens | Cornea | 2c | single | centre of the lens Repeat from Nov 08 Refractive index of each component of the eye as optical system Refractive medium Refractive index Air 1.000 Cornea ea 1.376 Aqueous humour 1.336 Lens (coex-core) 1.386-1.406 Vitreous humour 1.336 "The refractive indices of the successive layers of the lens increase from the periph... | Ophthalmology | null |
a0a77e03-b143-41ef-9b2e-9e0228b4bb9c | Which of the following extraocular muscle of the eye is involved in intorsion, depression and abduction of the eyeball? | Inferior rectus | Superior rectus | Inferior oblique | Superior oblique | 3d | multi | Superior oblique muscle of the eye innervated by the trochlear nerve is involved in intorsion (primary action), depression (secondary action) and abduction (teiary action) of the eyeball. Action of extraocular muscles: Muscle Primary action Secondary action Teiary action Medial rectus Adduction Lateral rectus Abduction... | Ophthalmology | null |
ef86c349-c7fa-4f18-8bd4-459bba39746d | Which layer of epidermis is underdeveloped in the VLBW infants in the initial 7 days: | Stratum germinativum | Stratum granulosum | Stratum lucidum | Stratum corneum | 3d | single | D i.e. Stratum corneum | Skin | null |
87cda92f-93e7-4e1d-be94-a8ca00ac5243 | All of the following are side effects of tacrolimus, EXCEPT: | Nephrotoxicity | Ototoxicity | Neurotoxicity | Hepatotoxicity | 1b | multi | Side effects with the use of tacrolimus includes nephrotoxicity, hepatotoxicity, hypeension, tremor, seizures, diabetes mellitus, neuropathy and blurring of vision. No ototoxicity has been observed. Ref: KDT 6th Edition, Page 840; Immunopharmacology By Manzoor M. Khan, Pages 91-3; Goodman and Gilman's The Pharmacologic... | Pharmacology | null |
8768ab05-55fa-44af-a3e5-1c5dc1ec2ccf | Bacillus anthracis - | Produces an endotoxin | Produces terminal bulging spores | Is an anaerobic organism | Capsule is demonstrated by M'Fadyyean's reaction | 3d | single | Anthrax is an endemic zoonosis in many countries; it causes human disease following inoculation of the spores of Bacillus anthracis. B. anthracis was the first bacterial pathogen described by Koch and the model pathogen for 'Koch's postulates' (see Box 6.1, p. 100). It is a Gram-positive organism with a central spore. ... | Medicine | Infection |
204b1a98-ee2b-4a7a-800f-4f2b7676280a | Weight gain is seen in all, except - | Phaeochromocytoma | Insulinoma | Myxoedema | Cushing's disease | 0a | multi | null | Medicine | null |
5ea216c9-2566-4ccd-9373-5111cb3d15ab | Shift to right of oxygen dissociation curve is caused by all, EXCEPT: | Fall in pH | Rise in temperatures | Decrease in 2,3 BPG | None of the above | 2c | multi | Three impoant conditions affect the oxygen-hemoglobin dissociation curve: the pH, the temperature, and the concentration of 2,3-biphosphoglycerate (BPG; 2,3-BPG). A rise in temperature or a fall in pH shifts the curve to the right. When the curve is shifted in this direction, a higher PO2 is required for hemoglobin to ... | Physiology | null |
6b739cfb-d435-455b-8397-5ce103a890da | Paralysis of 3rd, 4th, 6th nerves with involvement of ophthalmic division of 5th nerve, localizes the lesion | Cavernous sinus. | Apex of orbit. | Brainstem | Base of skull. | 0a | single | A i.e. Cavernous sinus Abrupt (sudden/ very rapid) onset of marked systemic features (high grade fever) with proptosis, chemosis especially with prostration, sequential ophthalmoplegia (i.e. initial lateal gaze involvement), bilateral involvement and mastoid edemaQ strongly suggest the diagnosis of cavernous sinus thro... | Ophthalmology | null |
2d6ba7c0-65de-43e3-b944-b9691304a125 | False about Haptens is | Haptens are high molecular weight molecules | Lack immunogenicity | Retain antigenicity | Complex haptens contain two or more epitopes | 0a | multi | Haptens are low molecular weight molecules. | Microbiology | null |
bd5e31c8-6bf8-43c3-ac5b-13af3a3bdfe3 | True about N2O – | Good muscle relaxant | Low potency and good analgesia | High potency and poor analgesia | None | 1b | multi | N2O is least potent (MAC = 105%).
It has a good analgesic but poor muscle relaxant activity. | Anaesthesia | null |
327dff34-716a-478e-afa3-6af8e8f134d2 | Incidence of absent of kidney is | 300 | 1500 | 3000 | 5000 | 1b | single | (1500) (1305-LB) (1286-B & L 25th)* An absent or grossly atrophic kidney is found in about 1:1400 individuals (1305-LB)* Renal ectopia - In approximately 1:1000 people, the kidney does not ascend, ectopic kidneys are usually found near the pelvic brim (1306-LB) | Surgery | Kidney & Ureturs |
d8bc84af-f2d2-4b8c-af71-a8b24c4f337b | BCG is not given to patient with - | Generalised Eczema | Infective dermatosis | Hypogammaglobulinaemia | All of the above | 3d | multi | <p>BCG Aim- To induce a benign,aificial primary infection which will stimulate an acquired resistance to possible subsequent infection with virulent tubercle bacilli, and thus reduce the morbidity and moality from primary tuberculosis among those most at risk. WHO recommends the &;Danish 1331&; strain for vaccine produ... | Social & Preventive Medicine | Communicable diseases |
55dd9223-eda6-4510-b629-180fafbe51cc | Depression of consciousness level in hypothermia stas when the core body temperature falls below: COMEDK 14 | 35degC | 34degC | 33degC | 32degC | 3d | multi | Ans. 32degC | Forensic Medicine | null |
d1e59725-a866-4732-9442-4704fce48006 | Most prevalent incidentaloma is: | Cushing's adenoma | Pheochromocytoma | Adrenocoical carcinoma | Non-functioning adenoma | 3d | single | Adrenal Incidentaloma- - Incidentally detected adrenal mass through imaging performed for unrelated disease Nonfunctioning adenoma - 82% of incidentalomas Preclinical cushing - 5% Pheochromocytoma - 5% Adrenocoical Ca - 5% Metastatic Ca - 2% Aldosterone producing adenoma - 1% | Surgery | Parathyroid and adrenal glands |
ab5e5093-7d78-4bcd-8c66-fb484c34b8a3 | Indomethacin can antagonize the diuretic action of loop diuretics by: | Preventing prostaglandin mediated intrarenal-hemodynamic actions | Blocking the action in ascending limb of loop of Henle | Enhancing salt and water reabsorption in distal tubules | Increasing aldosterone secretion | 0a | single | Loop diuretics release PGs that induce intrarenal hemodynamic changes which secondarily affect salt output. Indomethacin and other NSAIDs inhibit the formation of PG. Therefore, NSAIDs blunt the action of loop diuretics. | Pharmacology | Kidney |
7ff148d9-0cbc-45d2-869d-6b9c48d43bc3 | Human Development Index is | Infant mortality, Longevity and Income | Knowledge, Longevity and Income | Infant mortality, Health infrastructure and Income | Environment, Longevity and Income | 1b | single | Ans. b (Knowledge, Longevity and Income). (Ref. Park PSM 22nd /pg. 16).# HUMAN DEVELOPMENT INDEX- Consist of three dimensions:- Longevity (life expectancy at birth);- Knowledge (Adult literacy rate and mean years of schooling); and- Income (real GDP per capita in purchasing power).- The HDI ranges between 0 to 1.- In I... | Social & Preventive Medicine | Concept of Health and Disease |
11bc2363-089e-4c91-949b-9b3b71bb4191 | Anti–Parkinsonism drug that is a selective COMT inhibitor : | Entacapone | Ropinirole | Pergolide | Pramipexole | 0a | single | null | Pharmacology | null |
596e290b-7d85-40bb-80ac-f5f4e3ff7da0 | Method of sterilization which is least effective is: | Pomeroy's technique | Laparoscopy | Vaginal fimbriectomy | Hysteroscopic tubal occlusion | 3d | single | Ans. is d i.e. Hysteroscopic tubal occlusion Coplc tubal occlusion Cauterisation (Failure rate 30%) Sclerosants (Failure rate 15%) I - Due to high failure rate these methods are obsolete now Hysteroscopic tubal occlusion is done by 2 methods and both these methods have high failure rates. Also Know : Pomeroy's method 0... | Gynaecology & Obstetrics | null |
dbee4d73-cd0b-4a60-a493-6c2d75f7d543 | The drug of choice for prevention of seizures in a patient with severe preeclampsia is | Phenytoin | Magnesium sulphate | Diazepam | Nidedipine | 1b | single | given by i.v. infusion, it has been used for long to control convulsions and to reduce BP in toxaemia of pregnancy. As per WHO, it is the drug of choice for prevention and treatment of seizures in preeclampsia and eclampsia Ref: KD Tripathih 8th ed. page 333 | Pharmacology | Central Nervous system |
2b73405f-a305-48b3-a332-e37b5d1635de | All of the following forces are involved in antigen antibody reaction, EXCEPT: | Vander Waal's forces | Electrostatic bond | Hydrogen bond | Covalent bond | 3d | multi | Answer is D (Covalent bond) : The combination between antigen and antibody is effected during the primary stage of an Ag-Ab reaction. This reaction is essentially reversible and effected by the weaker intermolecular forces such as: Vander Waal's, Hydrogen bonds, Ionic bonds and not by the firmer covalent bonds. Frequen... | Medicine | null |
f3f80bf2-8fb3-4a23-8de7-a16daf437f98 | Not true about deep cervical lymph nodes | Lie along external jugular vein | Tonsil is drained by jugulodigastric nodes | Lie deep to sternocleidomastoid | Tongue drains into juguloomastoid | 0a | multi | The deep cervical lymph nodes are situated along the internal jugular vein, and include the jugulodigastric node below the posterior belly of the digastric and the jugulo-omohyoid node above the inferior belly of the omohyoid Ref : B D Chaurasia's Human Anatomy, seventh edition, volume 3 , pg. no. 100 ( fig. 8.28 - pg.... | Anatomy | Head and neck |
d39195a7-ef88-4fcc-94e6-bc40558deb78 | Which anesthetic agent is contraindicated in porphyria: | Propofol | Ketamine | Thiopentone | Etomidate | 2c | single | Ans: (c) ThiopentoneRef: KDT 6th ed./374* Thiopentone is an ultrashort acting thiobarbiturate because of rapid redistribution.* It has poor analgesic property.* I/v injection is very painful. Therefore it is contraindicated unless opioids or N2O has been given.* Contraindicated in porphyria patientsAlso Know*Etomidatei... | Anaesthesia | Miscellaneous General Anesthesia |
84169e30-a64b-46e4-8b2a-dba4c48c9691 | Biconcave shape of RBC is due to binding of spectrin to- | Ankyrin | Actin | Myosin | Adducin | 0a | single | Ans. is 'a' i.e., Ankyrin * RBCs biconcave shape is due to membrane cytoskeleton.* RBC membrane cytoskeleton contains a filamentous meshwork of proteins that form a membrane cytoskeleton along the entire cytoplasmic surface of membrane. The most abundant and most important protein in this membrane cytoskeleton is Spect... | Physiology | Heart, Circulation, and Blood |
a9481537-87cf-4175-9ba4-43f3c74481a8 | Lipid peroxidation of polyunsaturated lipids of subcellular membranes produces - | Hemosiderin | Lipofuscin | Both of above | None of above | 1b | multi | Lipofuscin is an insoluble pigment, also know n as lipochrome or wear-and-tear pigment.
Lipofuscin is composed of polymers of lipids and phospholipids in complex with protein, suggesting that it is derived through lipid peroxidation of polyunsaturated lipids of subcellular membranes.
Lipofuscin is not injurious to the ... | Pathology | null |
7884936c-058c-4536-8d29-b6851f7f7148 | A 35 years old man gets up from sleep with sudden onset breathlessness, anxiety, palpitation, shaking hand, profuse sweating, discomfort in chest & fear of dying. There is history of similar episodes in past. Physical examination is normal. Probable diagnosis is- | Panic attack | Anxiety disorder | Conversion disorder | Acute psychosis | 0a | single | Ans. is 'a' i.e., Panic attack * Sudden onset of breathlessness, anxiety, palpitation and feeling of impending doom suggest the diagnosis of panic attack (severe anxiety)* A panic attack has following characteristics: -A. Discrete episode of intense fearB. Abrupt onset (sudden onset)C. Reaches as maximum within few min... | Psychiatry | Anxiety & Stress |
4156b9a1-af3b-44e9-9581-7051ea807c4a | Rhinophyma complicates- | Acne vulgais | Acne rosacea | Psoriasis | Phemphigus | 1b | single | Ans: B | Unknown | null |
b08cf1a0-d950-4b06-b41a-94db605cbc42 | Hypoglycemia in new born is seen in:a) IUGRb) Mother with hypothyroidismc) Rh incompatibilityd) Macrosomiae) Hyperthyroidism | b | ad | ac | ab | 1b | single | Hypoglycemia is defined as blood glucose of less than 40 mg/dL, irrespective of the gestational age.
Causes of hypoglycemia Let us see each option one by one.
Option ‘a’ IUGR
“Hypoglycemia is due to shortage of glycogen reserve in the liver as a result of chronic hypoxia”
Dutta Obs. 6/e, p 465
Option ‘b’ Mother with hy... | Gynaecology & Obstetrics | null |
b53771ca-5ce3-42a6-9282-48f8334052e6 | Which of the following is the major anaplerotic enzyme? | Pyruvate carboxylase | Acetyl-CoA carboxylase | Pyruvate dehydrogenase | Succinate dehydrogenase | 0a | single | Ans. a)Pyruvate carboxylase Anaplerotic (gap-filling) reactions are the reactions that replenish the depleted TCA cycle intermediates that were used up in the biosynthetic reactions. Oxaloacetate is the catalyst of TCA cycle. Thus, production of oxaloacetate is the major anaplerotic reaction. Intermediate Depleted (use... | Biochemistry | Gluconeogenesis |
d731c828-2ac0-424b-85f5-5afb4a3aadf6 | Toxoid is prepared from - | Exotoxin | Endotoxin | Both | None | 0a | multi | Ans. is 'a' i.e., Exotoxin Toxoids o Ceain organisms produce exotoxins e.g., diphtheria and tetanus bacilli. o The toxin produced by these organisms are detoxicated and used in the preparation of vaccines. o The antibodies produced neutralize the toxic moiety produced during infection, rather than act upon the organism... | Social & Preventive Medicine | null |
84079a14-b669-462d-b674-064f7b544b24 | In pancoast tumor, following is seen except? | Homer's syndrome | Rib erosion | Haemoptysis | Pain in shoulder and arm | 2c | multi | Answer is 'c' i.e. Haemoptysis Haemoptysis is seen in central tumors or endobronchial growth (Pancoast tumor is a peripheral tumor) Pancoast's tumor (also k/a superior sulcus tumor) Is a tumor of the apex of the lung It may grow to cause shoulder and arm pain - d/t involvement of C8, TI & 72 nerves Erosion of ribs Home... | Surgery | null |
e70568ce-2614-4039-aec8-beac52e0bbd1 | In prophylaxic of Manic depressive psychosis, drug used is -a) Lithium carbonateb) Carbamazepinec) Valproated) Haloperidol | abc | bc | acd | bcd | 0a | single | null | Psychiatry | null |
41256fd7-a11f-4523-8d4f-e3433d2d11b8 | A patient presented with a 1 x 1.5 cms growth on the lateral border of the tongue. The treatment indicated would be. | Laser ablation | Interstitial brachytherapy | External beam radiotherapy | Chemotherapy | 1b | single | Ans- B Interstitial brachytherapy Ref- Although this study is retrospective, the results are noteworthy, considering its long follow up and the description of results in terms of LCR, toxicities, and functional outcome. Our study recommends treating patients with brachytherapy alone in T1 stage and demonstrates the nee... | Unknown | null |
780aac4d-5b27-4253-95a1-54a2c85e3933 | Colour of nitrous oxide cylinder is? | Blue | Blue body with white shoulder | White | Black | 0a | single | N2O (blue) Cyclopropane (orange) Oxygen (black & white) Entonox (blue & white) | Pharmacology | FMGE 2019 |
780efbc7-f97e-4458-8f0e-7fdb689ef333 | A 45 year old female presents with 48 hour history of right upper quadrant pain, dyspnea, non-productive cough, fever with chills and rigor. The pain radiates to right shoulder tip. She has history of perforated duodenal ulcer repair 3 weeks ago. Temperature 39.3degC. O/E there is acute tenderness over right hypochondr... | Acute pancreatitis | Subphrenic abscess | Acute cholangitis | Pyonephrosis | 1b | single | Ans. (b) Subphrenic abscessRef: Bailey 26th edition Page 977* Bailey says- "Pus Nowhere, Pus Some where- search Pus Under the Diaphragm"* In a post op case (patient lying)- most dependent site of abscess formation is Subphrenic Space | Surgery | Miscellaneous |
8a78d29e-fad5-4d68-a9b2-0d3f1f99e917 | Donovan bodies are seen in ? | Leishmaniadonovani | Chlamydia trachomatis | Klebsiella | Calymmatobacteriumgranulomatis | 3d | single | Ans. is 'd' i.e., Calymmatobacteriumgranulomatis | Skin | null |
352b628b-1a67-417c-a03c-35c8e00df1fc | Stroke volume is increased by - | Increased end-diastolic and end-systolic volumes | Decreased end-diastolic and end-systolic volumes | Increased end-diastolic volume and decreased end-systolic volume | Decrased end-diastolic volume and increased end- systolic volume | 2c | single | Ans. is 'c' i.e., Increased end-diastolic volume and decreased end-systolic volume o The stroke volume is the amount of blood pumped out by left ventricle in each stroke.o Stroke volume is given by the difference between end-diastolic ventricular volume (the volume of blood in the left ventricle at the end of diastole;... | Unknown | null |
bc50d6de-b016-4225-ae6d-31279cce961f | When do we have to start antibiotics to prevent post-operative infection? | 2 days before surgery | After surgery | 1 week before surgery | 1 hour before surgery & continue after surgery | 3d | single | Prophylactic antibiotics are administered before the skin incision is made. Repeat dosing occurs at an appropriate interval, usually 3 hours for abdominal cases or twice the half-life of the antibiotic.
Perioperative antibiotic prophylaxis generally is not continued beyond the day of surgery. | Surgery | null |
2fb81416-9675-41ff-8a77-89c05faf0ed0 | Which is not a manifestation of congenital toxoplasmosis - | Chorioretinitis | Hydrocephalus | Intracranial calcification | Cerebellar atrophy | 3d | single | null | Medicine | null |
ad7eb2f7-27de-4544-b81f-16aa8d41672a | Tumor represented as T3N2M0 is: | Stage1. | Stage 2 | Stage 3 | Stage 4 | 3d | single | null | Pathology | null |
d11285d1-e748-455c-b577-78dd8ee981a4 | Comment on the diagnosis of the ECG tracing shown below. | First degree AV block, intranodal | Second degree AV block type1, intranodal | Second degree AV block type 2, infranodal | Third degree AV block | 2c | single | Symmetry in PR interval before and after the missed beat --> Indicating Second degree AV block type 2: infranodal. In Second degree AV block type 1 --> Serial lengthening of PR interval before and after the missed beat. In Third degree AV block --> complete dissociation b/w atria and ventricles. | Medicine | ECG and Arrhythmia 2 |
aa6af1b3-a2cc-4502-8d8c-e3f490df2202 | A businessman notices a lump in front of his ear while shaving one morning. His wife thinks it has been there for several months. What is the most likely cause of a mass in the parotid gland in this patient? SELECT ONE. | Lymphoma | Squamous cell carcinoma | Metastatic skin cancer | Benign mixed tumor | 3d | single | Benign mixed tumor (pleomorphic adenoma) requires appropriate excision (superficial parotidectomy). If the tumor is shelled out, recurrence is likely. Approximately 80% of tumors of the salivary glands occur in the parotid gland. | Surgery | Salivary Gland |
f94cd6b4-8474-4218-85de-0e7b819b89e5 | Grenz zone is absent in which type of leprosy | TT | BT | BB | LL | 0a | single | LEPROSY:- Ref:- Review of Dermatology by Alikhan; pg num:-303 | Dental | Bacterial infections |
c9e49eb7-f692-470b-bb47-955f6c088bc0 | Bone density is decreased in which of the following - | Osteoporosis | AVN of bone | 0steopetrosis | Fracture and collapse of cancellous bone | 0a | single | Osteoporosis is characterized by an abnormally low bone mass (reduced bone density) and defects in bone structure. | Orthopaedics | null |
0efec796-2798-4bd3-9177-b0ceda2e684a | Flexion of metacarpophalangeal joint is produced by? | Lumbricals | Dorsal interossei | Palmar interossei | All of the above | 3d | multi | Ans. is 'd' i.e., All of the aboveMetacarpophalangeal joints o These are ellipsoid joints between head of metacarpals and base of proximal phalanx. Movement at MCP joints are flexion, extension, abduction and adduction.Movement Muscles producing movementsFlexion Main muscles :- The lumbricals and the interossei. Suppoi... | Anatomy | null |
51594e84-57cf-4386-b140-d24e8af51154 | Thornwaldt cyst is also called as: | Laryngeal cyst | Nasopharyngeal cyst | Ear cyst | None | 1b | multi | Thornwaldts bursa is also called as nasopharyngeal bursa, hence thornwaldts cyst is also called as Nasopharyngeal cyst. | ENT | null |
7b0b4532-c5c0-4147-bba9-e740fd7700af | Best treatment for meningioma with low recurrence rate is | Tumour excision with cyst of dura mater removal | Excision surgery followed by radiotherapy | Chemotherapy | Preop embolization + Excision surgery | 3d | single | The best treatment for meningioma of low recurrence rate is complete tumour resection including resection of underlying bone and associated dura. The constant principles in meningioma resection are the following: If possible, all involved or hyperostotic bone should be removed. The dura involved by the tumor as well as... | Surgery | Urology |
87270a0a-20f2-41d9-8f0c-8c3cf1c21e08 | Condyloma acuminata is repoed on pap-smear as - | Inflammatorycondition | Carcinoma | Carcinoma in situ | LSIL | 3d | single | Ans. is'd'i.e.LSIL Cervical Precursor lesion associated with both low and high risk HPV subtypes.This category includes:Flat mature LSIL (flat condyloma or CIN-I)Mature Exophytic LSIL (exophytic condyloma, condyloma acuminatum)Extensive Exophytic LSIL (giant condyloma)Immature Exophytic LSIL (immature condyloma, squamo... | Gynaecology & Obstetrics | null |
778a7522-0afd-454b-8f14-8e09a60ced57 | Angle of jaw (or) skin over angle of mandible is supplied by | Great auricular nerve | Lesser occipital nerve | Greater occipital nerve | Posterior auricular nerve | 0a | single | null | Anatomy | null |
c8d393ac-347e-4f5b-b40e-36599a4dd493 | Minamata disease in Japan is caused by toxicity of | Mercury | Arsenic | Lead | Silver | 0a | single | (A) Mercury > Minamata disease (Chisso-Minamata disease), is a neurological syndrome caused by severe mercury poisoning. Symptoms include ataxia, numbness in the hands and feet, general muscle weakness, narrowing of the field of vision and damage to hearing and speech. In extreme cases, insanity, paralysis, coma and de... | Medicine | Miscellaneous |
ddec0360-fd1d-4f7e-93cb-80c95aefaa7b | A test which produces similar results when repeated, but values obtained are not close to actual/true value,is: | Precise but inaccurate. | Precise but accurate. | Imprecise and accurate. | Imprecise and inaccurate. | 0a | multi | null | Dental | null |
84ff8412-d46a-46d5-aaaf-3ab7076a48c1 | Glucose transpo along cell membranes occurs along with | K+ | Na+ | CI | HCO3 | 1b | single | The co-transpo system may either be a sympo or an antipo. In sympo, (Fig. 2.12) the transpoer carries two solutes in the same direction across the membrane, e.g. sodium-dependent glucose transpoer (Chapter 8). Phlorhizin, an inhibitor of sodium-dependent co-transpo of glucose, especially in the proximal convoluted tubu... | Biochemistry | Respiratory chain |
cff7b4ff-3420-43d9-8b18-1f6f9ec1227b | Verocytotoxin of E. coli acts by - | Increasing cAMP | Decreasing cAMP | Decreasing protein synthesis | Decreasing cGMP | 2c | single | Ans. is 'c' i.e., Decreasing protein synthesis | Microbiology | null |
6fa26c39-5db5-4c39-a72c-039c195a4410 | A patient with acute psychosis, who is on haloperidol 20 mg/day for last 2 days, has an episode characterized by tongue protrusion, oculogyric crisis, stiffness and abnormal posture of limbs and trunk without loss of consciousness of last 20 minutes before presenting to casualty. This improved within a few minutes afte... | Acute dystonia | Akathisia | Tardive dyskinesia | Neuroleptic malignant syndrome | 0a | single | Antipsychotic drugs Extrapyramidal symptoms- dur to D2 blockade in limbic system Extrapyramidal symptoms Clinical features Special DOC Acute dystonia Oculogyric crisis ocular muscles spasm and opisthotonos Toicollis Protrusion of tongue leading to laryngospasm Grimacing Earliest to develop (days) Anticholinergic drugs ... | Psychiatry | Schizophrenia Spectrum and Other Psychotic Disorders |
e989ce58-fde9-4146-8381-80f067d5b7a2 | Blanket/ mass treatment is indicated in all EXCEPT: September 2004 | Trachoma | Malaria | Yaws | Dengue fever | 3d | multi | Ans. D i.e. Dengue fever | Social & Preventive Medicine | null |
643a6440-e1e2-4c25-8725-f7ef36e63bdb | Hoffbauer's cells are present in | Pituitary gland | Parathyroid | Placenta | Pineal gland | 2c | single | null | Anatomy | null |
2d3252ca-332e-4444-9274-c63b132bcda6 | Mucin layer tear flilm deficiency occurs in: | Keratoconjunctivitis sicca | Lacrimal gland removal | Canalicular block | Herpetic keratitis | 0a | single | A i.e Keratoconjunctivitis sicca | Ophthalmology | null |
f16dcf58-7d56-42f8-987c-1c51f6f5de00 | Reactive ahritis is a result of exposure to all of the following, EXCEPT: | Chlamydia species | Campylobacter jejuni | Salmonella enteritidis | None of the above | 3d | multi | Reactive ahritis is an inflammatory condition that occurs after exposure to ceain gastrointestinal and genitourinary infections, paicularly Chlamydia species, Campylobacter jejuni, Salmonella enteritidis, Shigella, and Yersinia. Patients may give a history of an antecedent genitourinary or dysenteric infection 1 to 4 w... | Medicine | null |
73bd3b2d-dddd-488a-ae79-9534c2dc08cb | Dose of Vit D in children with malnutrition - | 100 IU | 200 IU | 50,000 IU | 10,000IU | 2c | single | Vitamin A deficiency treatment: Vitamin A on days 1,2 and 14 each Age >12 months - 200,000 IU Age 6-12 months - 100,000 IU for age 0-5 months - 50,000 IU Ref: Guidelines for the inpatient treatment of severely malnourished children, WHO Pgno : 23 | Social & Preventive Medicine | Nutrition and health |
27458d5e-dce2-47fb-b068-7cd20c2f9e2c | All are components of basement membrane except | Nidogen | Laminin | Entactin | Rhodopsin | 3d | multi | Ans. is 'd' i.e. Rhodopsin Basement membrane is a part of extracellular matrix Extracellular matrix is composed ofCollagenThey are family of proteins which provide structured support to the multicellular organisms.It is the main component of tissues such as fibrous tissue, bone, cartilage, valves of heart, cornea, base... | Pathology | Glomerular Diseases |
9a6d2151-e58e-4142-ade8-fd2c75033064 | The following are the contraindications of BAL except: | G6PD deficiency | Iron poisoning | Cadmium poisoning | Gold poisoning | 3d | multi | BAL (British anti-lewisite, dimercaprol): It is used in arsenic, lead, bismuth, copper, mercury, gold and other heavy metal poisoning. Dose: 10% solution in oil, 3-5 mg/kg IM 4 hourly for 2 days, 6 hourly on 3rd day and then 12 hourly for next 10 days. Side effects: Nausea, vomiting, headache and hypeension. Contraindi... | Forensic Medicine | Toxicology - 1 |
a324c5d0-27d9-48fb-8571-0194e9c6a9bc | A neonate presented on day one of life with bilious vomiting. First investigation to be done is: | Chest skiagram | Babygram | Ultrasound | Manometry | 1b | single | Ans. b. Babygram (Ref: Nelson 19/e p1278; Sabiston 19/e p1841-1842; Schwartz 9/e p1427-1428; Bailey 26/e 120, 25/e p85; Shackelford 7/e p811-813)A neonate presented on day one of life with bilious vomiting. First investigation to be done is Babygram (full body radiograph of the baby) to rule out duodenal atresia. Babyg... | Pediatrics | Stomach and Intestines |
9176e5b4-1fdd-4de6-a0d2-f80f6357df63 | In atrial septal defect, the aoa is | Small | Normal | Enlarged | Aneurysmal | 0a | multi | The chest x-ray film is often, but not always, abnormal in patients with significant ASD. Cardiomegaly may be present from right hea dilation and occasionally from left hea dilation if significant mitral regurgitation is present in the patient with an ostium primum ASD. Right hea dilation is better appreciated in later... | Medicine | All India exam |
28514d68-7676-4aab-ba47-81f7d27acb72 | Which complex in mitochondria is not involved in proton transpor during ETC ? | Complex I | Complex II | Complex III | Complex IV | 1b | single | Ans. is 'b' i.e., Complex IIInner mitrochondrial membrane is impermeable to protons; therefore, proton pumps are required to pump protons (hydrogen ions) from mitochondrial matrix to the intermembrane space.The complex I (Site I), complex III (Site II) and complex IV (Site III) act as proton pumps ejecting protons (hyd... | Biochemistry | null |
cfcd6d6f-53f1-48bf-bc88-92eba9ebd683 | False statement is | Repressor binds operator gene | Regulator genes produce repressor subunits | IP TG is inducer but not substrate | Regulator gene is inducible | 3d | multi | D i.e., Regulator gene is inducible | Biochemistry | null |
dc10ceba-1634-40db-a017-c1f5f14bfe59 | Parvovirus B19 does not cause: | Roseola infantum | Aplastic anemia in sickle cell disease | Fetal hydrops | None of the above | 0a | multi | Ans. is 'a' i.e. Roseola infantum ParvovirusParvovirus is the smallest virus.It is a nonenveloped icosahedral virus with linear single stranded D.N.A.Pathogenesis of parvovirusParvovirus is highly tropic for human erythroid cells.The cellular receptors for parvovirus is blood group P antigen.P antigen is expressed on m... | Microbiology | Parvovirus |
261c797d-55fd-4113-a69e-eac7e955ad8c | Barbiturates excretion in urine may be increased by- | Diuretics | Alkalinization | Acidification | Dialysis | 1b | single | In barbiturate poisoning, forced alkaline diuresis is used. | Forensic Medicine | null |
439c80c9-7747-42e2-99e1-55d8da3ae5d7 | All are features of raised intracranial tension in adults except: | Erosion of dorsum sella | Erosion of posterior clinoid process | Inner table convolutions | Sutural diastasis | 3d | multi | Ans. Sutural diastasis | Radiology | null |
7221eee4-848b-46c8-940d-abfdcae26fa2 | Which of the following is not a branch of ophthalmic nerve? | Frontal nerve | Lacrimal nerve | Nasociliary nerve | Middle ethmoidal nerve | 3d | single | null | Anatomy | null |
1d2faca9-908a-4e65-8e0d-65314146f8f8 | Superantigens area) Erythrotoxin of Staph. aureusb) Clostridium difficile toxinc) Staphyloccocal toxic shock syndrome toxind) Cholera toxin | a | bc | ad | ac | 3d | single | null | Microbiology | null |
699961d7-3fea-450f-850c-a143be35d16e | The periphery of the retina is visualized with | Indirect binocular ophthalmoscopy | Direct ophthalmoscopy | Contact lens | Goldman's three mirror contact lens | 0a | single | The technique of examining the fundus of the eye is called ophthalmoscopy. In indirect ophthalmoscopy, a real and inveed image is formed between the condensing lens and the observer. The advantage of stereopsis (depth perception) and a larger field of view makes indirect ophthalmoscope (IDO) more useful both in retina ... | Ophthalmology | Anatomy, Development and clinical examination |
95f0687f-dc3f-40bb-aca5-590139b70b04 | Which of the following statement is true regarding race determination? | Negroid - Cut section of hair elliptical & mesaticephalic skull | Mongoloid - Cut section of hair Round & Dolicocephalic skull | Caucasoids - Cut section of hair Round & Mesaticephalic skull | Negroid - Cut section of hair oval & brachycephalic skull | 2c | multi | null | Forensic Medicine | Human identification |
61c76243-7f37-4564-b6c1-3f3c9079566b | Anacrotic pulse in felt in- | AR | MR | MS | AS | 3d | single | null | Medicine | null |
395b26a7-f537-4f3f-ae7f-d274d3a92b40 | Which of the following is a false statement about the respective fungal infections? | Candida albicans causes skin infection | Superficial layers of skin are involved | Microsporium involves nail | Epidermophyton doesn't involve hair | 2c | multi | Microsporium doesn't involve nail. Trychophyton involves skin, nail and hair. | Skin | null |
f2bd2545-9202-4300-9db2-82c3682397dc | Cell-matrix adhesions are mediated by? | Cadherins | Integrins | Selectins | Calmodulin | 1b | single | The cell adhesion molecules (CAMs) are classified into four main families:- * Immunoglobulin family CAMs *Cadherins * Integrins: bind to extracellular matrix (ECM) proteins such as fibronectin, laminin, and osteopontin providing a connection between cells and extracellular matrix (ECM) * Selectins | Pathology | General Concepts |
70b0d2e7-3d23-4763-81a2-6a68a7fb43e1 | The Hb level is healthy women has mean 13.5 g/dl and standard detion 1.5 g/dl, what is the Z score for a woman with Hb level 15.0 g/dI - | 9 | 10 | 2 | 1 | 3d | single | Ans. is 'd' i.e., 1.0 Thus the Z score for the woman in question is 1.0. Very simple funda to calculate Z score Normal variate indicates that the given observation is how many standard detion away from the mean. Here mean is 13.5 g/c11, SD is 1.5 g/dl and observation is 15 g/dl. That means observation (15 g/dl) is 1 SD... | Social & Preventive Medicine | null |
a01017de-8039-4c1e-bacf-07827ec5bd8d | Development of pellagra like skin lesion in carcinoid syndrome is due to: | Inadequate conversion of Tryptophan to Niacin | Dietary Niacin deficiency | Serotonin induced skin rash mimicking pellagra | Paraneoplastic manifestation | 0a | single | One of the main secretory products of carcinoid tumors involved in the carcinoid syndrome is serotonin which is synthesized from tryptophan. Up to 50% of dietary tryptophan can be used in this synthetic pathway by tumor cells, and this can result in inadequate supplies for conversion to niacin; hence, some patients (2.... | Medicine | null |
bfca29b5-7ebf-42e3-bfc3-75117f4c10a0 | Drug of choice for absent seizures | Clonezapam | Diazepam | Phenytoin | Valproate | 3d | single | Many children appear to have a genetic predisposition to absence seizures. In general, seizures are caused by abnormal electrical impulses from nerve cells (neurons) in the brain. Ref: KD Tripathi 8th ed. | Pharmacology | Central Nervous system |
18909583-00d9-4b14-98b6-b8b1be699b58 | Which of the following is low flow Oxygen delivery device | Nasal cannula | Venti-mask | Bag & mask ventilation | Aerosol system | 0a | single | A nasal cannula is generally used wherever small amounts of supplemental oxygen is required, without rigid control of respiration, such as in oxygen therapy. Most cannulae can only provide oxygen at low flow rates--up to 5 litres per minute (L/min)--delivering an oxygen concentration of 28-44%. Rates above 5 L/min can ... | Anaesthesia | Anaesthetic equipments |
89869129-75b9-4038-a5e4-65e2114c20db | Which of the following is not an ester – | Amethocaine | Benzocaine | Procaine | Bupivacaine | 3d | single | Bupivacaine is an amide. | Anaesthesia | null |
1755da4d-bb8e-48be-8fe5-290fdcdd30d9 | How will you check the quantitative assessment of liver function - | Degree of Transaminases | Degree of Alkaline phosphatase | Galactose metabolism | All the above | 2c | multi | The determination of the galactose elimination capacity with the method according to Tygstrup is the only test which detects the "functional hepatocyte mass" and thus constitutes a quantitative test for the metabolic function of the liver. In this determination of the maximum hepatic elimination capacity, differences w... | Medicine | G.I.T |
358b418a-31d5-4ec8-9a1c-3785667efc69 | Which of the following is detected by the antigen detection test used for the diagnosis of P. Falciparum malaria | Circum-sporozoite protein | Merozoite surface antigen | Histidine-Rich-Protein I (HRP-I) | Histidine-Rich-Protein II (HRP-II) | 3d | single | A useful approach is immunodiagnosis of malaria by detection of parasite-specific antigens using monoclonal antibodies The Para-Sight-F test (BD) is a dipstick antigen capture test targeting the "histidine-rich protein-2" (HRP-2), specific for P.falciparum. The test is sensitive, specific and rapid, results being ready... | Microbiology | parasitology |
d2545c07-472c-4b41-b519-f871a9fd4a5a | Iron overload occurs in all except | Thalassemia | Myelodysplastic syndrome | Polycythemia vera | Sideroblastic anemia | 2c | multi | Ref Harrison 19 th ed pg 626, 673 Increased erythropoietin leads to increased haematopoasis and an increased demand for iron producing a state of iron deficiency. Polycythemia vera being a state of increased erythropoietin is a cause of iron deficiency rather than iron overload. | Anatomy | Haematology |
784e9873-038a-4710-8440-2a30d1c28b00 | A child is brought to the emergency depament with signs of meningeal irritation. She had suppurative otitis media in the last week. Infection of middle ear can spread to CNS through: | Venous plexus | Cochlear aqueduct | Cochlear nerve sheath | Bloodstream | 1b | single | In the setting of middle ear infection, bacterial infection can invade through the round window causing acute suppurative labyrinthitis. From the labyrinth, bacteria gain access to the cochlear aqueduct, forming a conduit between the perilymph and the cerebrospinal fluid (CSF) resulting in meningeal infiltration. | ENT | null |
8a0ecade-9034-4164-921e-23c6cd6cc210 | Strategies for prevention of Neonatall Tetanus include all of the following except - | 5 clean practices | Giving penicillin to all the new borns | 2 doses of TT to all pregnant women | Immunizing all married women | 1b | multi | <p> Injection penicillin to all neonate. Reference:Park&;s textbook of preventive and social medicine,K.Park,23rd edition,page no:310-313. <\p> | Social & Preventive Medicine | Communicable diseases |
8bb969e7-ffde-4467-a438-5ac6c31a97e1 | Antibody in cold agglutin disease is | IgA | IgG | IgE | IgM | 3d | single | Cold agglutinin disease (CAD): This designation is used for a form of chronic AIHA that usually affects the elderly. First, the term cold refers to the fact that the autoantibody involved reacts with red cells poorly or not at all at 37degC, whereas it reacts strongly at lower temperatures. As a result, hemolysis is mo... | Microbiology | Immunology |
d51ced72-d895-4e62-8802-75d729faf679 | Type I hypersensitivity is mediated by which of the following immunoglobulins ? | Ig A | Ig G | Ig M | Ig E | 3d | single | Harshmohan textbook of pathology 7th edition. *type 1 or anaphylactic or atopic reaction mediated by humoral antibodies of IgE type or reagin antibodies in response to antigen. | Pathology | General pathology |
9c132f51-5d8e-49ae-971b-a1be39280ff1 | Coronal suture completely fuses by the age of: | 20yrs. | 30 yrs. | 40 yrs. | 45 yrs. | 3d | single | Actually Coronal suture completely fuses by 50-60 years, but the maximum age given in this question is 45 years and hence the answer. Age from Skull Sutures- Two halves of mandible unite at- 2 years. Metopic suture (2 halves of frontal bone) closes at: 3 years. Coronal, Sagittal, Lambdoid sutures sta to close on inner ... | Surgery | null |
e07ee6b3-284c-4872-9242-4d01aac86bdd | Position of the patient should be as described except | Diagnostic laparoscopy- trendlelnburg with about 30 degree tilt | Colposcopy - Lithotomy | Transvaginal sonography in Gynecology - Lithotomy with full bladder | Hysteroscopy - Lithotomy | 2c | multi | Bladder should be empty during a transvaginal ultrasound | Gynaecology & Obstetrics | Gynaecological diagnosis and operative surgery |
8aa342a8-fe4d-48ef-ba5e-7adf943b9804 | An adult whose both lower limbs are charred along with genitalia has burns - | 18% | 19% | 36% | 37% | 3d | multi | null | Surgery | null |
a6611387-79c2-4775-831b-e12da65468a8 | Mitral valve vegetations do not usually embolise to | Lung | Liver | Spleen | Brain | 0a | multi | Ref Harrison 19 th ed pg 820 Mitral valve vegetation would obviously not go to the lung, as that would involve a backward flow | Anatomy | General anatomy |
1cdff4dc-9300-4202-88e7-e3ef0670694f | Most common type of veex presentation: | Right occipito posterior | Left occipito transverse | Right occipito anterior | Left occipito anterior | 1b | single | M.C. position of veex is Left occipito Transverse(40%) LOT > LOA M.C. malposition of veex presenting pa is Right Occiputo posterior. | Gynaecology & Obstetrics | Labour - III |
9934bc64-0ac7-46ab-a7ec-a22d3100118c | Cephalic index of Mongolians is | <70 | 70-75 | 75-80 | >80 | 3d | single | Cephalic index (Index of Breadth) is Maximum Breadth of Skull / Maximum Length of Skull. From the Cephalic index, race can be determined in 85 - 90% of cases. The skull of an Indian is Caucasian with a few Negroid characters. Type of skull Cephalic index Race Dolicocephalic (long-headed) 70-75 Pure Aryans, Aborigines, ... | Forensic Medicine | Identification |
5958a8c0-5655-4ead-880e-744805ea3ab6 | In nephrotic syndrome, which infection is more commoner in children: September 2010 | Cellulitis | Pneumonia | UTI | Bacterial peritonitis | 3d | single | Ans. D: Bacterial peritonitis | Pediatrics | null |
3655236d-ad6a-455e-b46f-fd3711518bd2 | Shoulder dystocia is suspected during a delivery after the delivery of the head, obstetrician asks the assistants to sharply flex the legs towards the abdomen. What is this maneuver? | McRobes maneuver | Rubin's maneuver | Wood Corkscrew maneuver | Zavanelli's maneuver | 0a | single | The McRobes maneuverThe maneuver consists of removing the legs from the stirrups and sharply flexing the thighs up toward the abdomen. The procedure caused straightening of the sacrum relative to the lumbar veebrae, rotation of the symphysis pubis toward the maternal head, and a decrease in the angle of pelvic inclinat... | Gynaecology & Obstetrics | General obstetrics |
31007be7-664e-4bcd-a99f-8653ed623b48 | Sclerostin is produced by? | Osteocytes | Osteoblasts | Osteoclasts | Chondrocytes | 0a | single | Sclerostin (SOST) is a glycoprotein produced by osteocytes. They also synthesize receptor activator of nuclear factor kappa B ligand (RANKL). Both of these are involved in regulating bone formation and resorption. EXTRA EDGE: Romosozumab, a humanized monoclonal antibody that binds to sclerostin, prevents sclerostin fro... | Medicine | Miscellaneous QBank |
51455579-b076-426b-b6f3-c18b608c9c42 | Which of the following is false about Digoxin | Dosage reduction is required in hepatic disease | Dosage direction is required in renal failure | It can cause bradycardia | It increases the force of contraction in congestive hea failure | 0a | multi | Refer kDT 7/e p516.. Medical useEdit Irregular heabeatEdit The most common indications for digoxin are atrial fibrillation and atrial flutter with rapid ventricular response, though beta blockers and/or calcium channel blockers are often preferred. There is tentative evidence that digoxin may increase the risk of death... | Pharmacology | Cardiovascular system |
c7cfcb91-d76f-4aeb-8cf9-d9f1060a0d10 | Renal Cortical imaging is done by - | DTPA | DMSA | MAG3 | UIH | 1b | single | Ans. is 'b' i.e., DMSAo For imaging of renal cortex Tc-99m-DMS A is used,o Other three agents (of options) are used for dynamic renal scintigraphy.Renal scintigraphy1) Static renal scintigraphyFor static renal scintigraphy Tc - 99m - DMSA (Dimercaptosuccinic acid) is used. DMSA is cleared by renal tubules. When DMSA is... | Radiology | Genito Urinary System |
3634e4e4-96b4-458c-b18e-5cac68351a18 | In liver, ethanol is conveed to ? | Methyl alcohol | Pyruvate | Acetaldehyde | Oxaloacetate | 2c | single | Ans. is 'c' i.e., Acetaldehyde | Biochemistry | null |
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