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135
df4194f3-f073-4a2f-bbbd-4ef8c8f235c1
Chauffers fracture involves what ?
Radial head
Radial styloid process
Ulnar styloid process
Base of 1st metacarpal
1b
single
Chauffeur&;s fracture, also known as Hutchinson fracture, is a type offracture of the forearm, specifically the radial styloid process. The injury is typically caused by compression of the scaphoid bone of the hand against the styloid process of the distal radius. Ref : essential ohopaedics maheshwari and mhaskar 9th e...
Orthopaedics
Elbow injuries
832bcf42-73dc-4560-9763-2a1118f0e9a3
"French paradox" is -
a) A wine and food-loving French population with a low incidence of obesity and cardiovascular disease
b) In spite of heavy smoking lower incidence bronchogenic carcinoma in France
c) A physical fitness conscious french population still having higher incidence of cardiovascular disease
d) In-spite of high sugar intake in diet a lower incidence of obesity and type 2 DM
0a
single
The French paradox is a catchphrase first used in the late 1980s, that summarizes the apparently paradoxical epidemiological observation that French people have a relatively low incidence of coronary hea disease (CHD), while having a diet relatively rich in saturated fats,in apparent contradiction to the widely held be...
Medicine
Miscellaneous
0a458506-183e-4e18-bad2-290c78ba7a75
A 64-year-old man with heart failure is recently started on 80 mg/day of furosemide. He now feels weak and tired, but notes that his heart failure symptoms have improved. There is no change in his urine output and he gets a good diuretic response every time he takes his furosemide.Select the characteristic ECG findings...
shortened PR interval
lengthened PR interval
lengthened QU interval
shortening of the QT interval
2c
single
Hypokalemia results in prolongation of the QU interval. The delayed repolarization in hypokalemia is best expressed at QU rather than QT prolongation since it can be difficult to separate the T wave from the U wave. In severe cases, the ST segments become depressed. Quinidine, even in therapeutic doses, can cause simil...
Medicine
C.V.S.
3574d806-4bdf-4a29-ae43-95038197816a
Diagnostic criteria for Bulimia nervosa are all EXCEPT
Binge Eating
Presence of other psychiatric disorders
Lack Of Control Over Eating Behaviour
Self Induced Vomiting
1b
multi
(B) Presence of other psychiatric disorders # BULIMIA NERVOSA (BN) is an eating disorder characterized by eating binges typically followed by efforts to purge calories through self-induced vomiting, laxative and/or diuretic abuse, prolonged fasting, or excessive exercise. Fear of weight gain leads to the characteristic...
Psychiatry
Miscellaneous
f432a29f-fb96-42f6-ab70-409939f232bb
Prolonged exposure to noise levels greater than the following can impair hearing permanently -
40 decibels
85 decibels
100 decibels
140 decibels
2c
single
Repeated or continuous exposure to the noise around 100 decibels may result in a permanent hearing loss; inner ear damage may vary from minor changes in the hair cells to complete destruction of the organ of Coi. Park's Textbook of Preventive and Social Medicine, 22nd edition, Page No. 689
Social & Preventive Medicine
Environment and health
110bfabe-5fa1-416d-b6e5-1508de0d5953
Defect in type II hyperlipidemia
Apo-E
Lipoprotein lipase
LDL receptor
None
2c
multi
Familial hypercholesterolemia (type Ha) is due to deficiency of functional LDL receptors as a result of different types of mutations.
Biochemistry
null
0f554ef9-502b-4c32-b7b2-9d777e5f8c50
Which of the following non collagenous protein of dentin prevents premature mineralization
Decorin and Biglycans
Dentin Phosphoprotein
Dentin Sialoprotein
All of the above
0a
multi
null
Dental
null
f123749e-885b-4380-ac09-4155873e8dda
What is meant by suppositious child -
Second born of a twin pregnancy
Child born out of wedlock
Child rear up by a woman & She claims the child
Heterozygous mother & father
2c
single
Ans. is 'c' i.e., Child rear up by a woman & She claims the child Suppositious child Suppositious child means a factitious child. o Women may pretend pregnancy as well as delivery & later produces a child as if it is her own. She may substitute a living male child for a dead child or for a living female child born of h...
Pediatrics
null
a675f50c-a1ba-4ab3-b9cb-dcb422a71130
Corneal endothelial cell count is done by -
Specular microscopy
Keratometry
Gonioscopy
Slit lamp
0a
single
Ans. is 'a' i.e., Specular microscopy o Specular microcopy is used for corneal endothelial density.Important corneal examinationsCsed foro Keratometry. Comeal topographyCurvature of corneao Specular microscopyCorneal endothelial densityo Slit lampCorneal opacityo PachymeterThickness of corneao Placido's discCorneal she...
Ophthalmology
Techniques of Ocular Examination and Diagnostic Tests
1a0f8a79-68d3-4e37-8a13-254449a94116
All are true about Amoebic liver abscess except: March 2007
Common site is right posterosuperior pa of liver
Alcoholics are susceptible to develop amoebic liver abscess
Anchovy sauce pus
Fever is the most common sign
1b
multi
Ans. B: Alcoholics are susceptible to develop amoebic liver abscess Amebic liver abscess is the most frequent extraintestinal manifestation of Entamoeba histolytica infection. This infection is caused by the protozoa Ehistolytica, which ascends the poal venous system. The right lobe (posterior superior quadrant) of the...
Medicine
null
b2d69172-c62f-43c9-9a27-f172eaa26f34
All of the following conditions are associated with primary amenorrhea except:
Testicular feminization syndrome
Stein-Leventhal syndrome
Turner's syndrome
Mayer Rockitansky Kuster Hauser Syndrome
1b
multi
Ans. is b, i.e. Stein-Leventhal syndromeRef: Shaw 15th/ed, p284-285The Stein-Leventhal Syndrome also known as Polycystic Ovarian Disease (PCOD) is an important cause of Secondary Amenorrhea in young women.Testicular Feminizing syndrome, Turners syndrome and Mayer Rokitansky Kuster Hauser syndrome are causes of Primary ...
Gynaecology & Obstetrics
Disorders in Menstruation
b4736868-8e5e-47d5-8cc2-7171be42f001
Toxic megacolon is most commonly associated with-
Ulcerative colitis
Crohn's disease
Whipple's disease
Reiter's disease
0a
single
null
Pathology
null
085e033e-d9c0-4729-bf92-3ae2476ceb22
What is the drug of choice for Obsessive Compulsive Disorder?
Imipramine
Fluoxetine
Benzodiazepines
Alprazolam
1b
single
Ans. (B) Fluoxetine(Ref: Harrison 17/e p2715; CMDT 2010/943; KDT 8/e p492)SSRIs are drug of choice for most of the neurotic disorders including OCD.
Pharmacology
C.N.S
6a874d5f-9034-45f4-98b0-238a6324205f
The cells most frequently found in a granuloma are
Mast cells
Giant cells
Lymphocytes
Neutrophilis
2c
single
null
Pathology
null
e303c83a-2e9c-410e-9210-f9dc2922fa0b
The drug causing curare like effects are all except
Chloramphenicol
Polymyxin
Tetracycline
Streptomycin
0a
multi
Refer KDT 6/e p 346 Drugs causing curare like effect are Aminoglycosides Polypeptide antibiotics Tetracycline Clindamycin, lincomycin
Pharmacology
Anesthesia
c3bbbc68-351b-4531-a498-5904f8e72f5c
Investigation of choice on Meckel's Diveicula in pediatric age group is
USG
CT
Barium meal
Na 99m Tc- peechnetate
3d
single
In case of children 99mTc-peechnetate is preferentially taken up by the mucus secreting cells of gastric mucosa and ectopic gastric tissue in Meckel's Diveicula. In adults less ectopic gastric tissue is seen so the test is not much accurate in adults Ref: Sabiston 20th edition Pgno :1285
Anatomy
G.I.T
28b41c40-7644-4ba7-a651-8ad79565a524
Os trigonum is which type of epiphysis ?
Aberrant
Pressure
Atavistic
Traction
2c
single
C i.e. Atavistic
Anatomy
null
34b45490-fa92-491a-8259-dd3bac546d23
Wolff-chaikoff effect is -
Reduced thyroxine synthesis by radiotherapy
Reduced thyroxine synthesis by propylthiouracil
Reduced thyroxine synthesis by iodides
None of the above
2c
multi
Ans. is 'c' i.e., Reduced thyroxine synthesis by iodides Iodine and Iodideso Iodine is the fastest acting thyroid inhibitor.o Most important action is inhibition of hormone release (thyroid constipation)\ but all facets of thyroid synthesis may be affected.o Excess iodide inhibits its own transport in thyroid cells and...
Pharmacology
Endocrinology
582e74bd-8b71-4d87-8b72-6859eefe1bda
Growth of virus in embryonated egg, eggs are incubated for -
4-8 hours
1-2 days
5-12 days
20-25 days
2c
single
Ans. is 'c' i.e., 5-12 days "For virus isolation, feile chicken eggs are incubated for 5-12 days, and a viral Suspension or suspected virus - containing" tissue is injected into the fluid of the egg.
Microbiology
null
896ec5ab-6b8b-4c15-956c-a7915a66b77c
Which of the following is primarily a bactericidal drug?
Chloramphenicol
Gentamicin
Sulphadiazine
Tetracycline
1b
single
Aminoglycosides: Streptomycin, Gentamicin, Amikacin, Neomycin, etc. are considered as bactericidal drugs.
Pharmacology
null
2e04b9c6-9a90-4773-8849-6560535c7e9d
Crown completion of Mandibular Canine occur
At birth
6-7 years
11-12 years
8-9 years
1b
single
null
Dental
null
a9b22c98-b7bf-48c1-ab6f-c3f535bd43d0
N K cell shows presence of -
CD 44
CD 16
CD 54
CD 32
1b
single
Ans. is 'b' i.e., CD 16 o NK cells have CD-56 and CD-16 on their surface.
Pathology
Cells and Tissues of Immune System
bb86ecf4-fb4a-4b2c-b907-3b6a85932a9c
A radiologist notes the presence of fine, radiographically dense crystals in the tissues of a knee joint. This patient most likely has which of the following types of ahropathy?
Gonococcal ahritis
Gouty ahritis
Osteoahritis
Pseudogout
3d
multi
Radiographically dense calcium pyrophosphate dihydrate (CPPD) crystals are deposited in cailage and joint soft tissues in pseudogout, which can involve the knees, wrists, elbows, shoulders, or ankles. If the patient is asymptomatic because the deposition is primarily within cailage, the condition is sometimes called ch...
Medicine
null
dc6a0ccc-e8c6-450d-bd3a-e9b51f8468b0
All are seen with Pneumocystis carini in AIDS except:
Pneumonia
Otic polypoid mass
Ophthalmic choroid lesion
Meningitis
3d
multi
In addition to pneumonia, a number of other clinical problems have been repoed in HIV-infected patients as a result of infection with P. jiroveci as:- Otic involvement may be seen as a primary infection, presenting as a polypoid mass involving the external auditory canal. In patients receiving aerosolized pentamidine f...
Medicine
viral infection
1baba4aa-943f-430c-9ddf-2aa1a730a471
All of the following aeries are common sites of occlusion by a except:
Left anterior descending
Right coronary aery
Circumflex coronary aery
Marginal aery
3d
multi
Answer is D (Marginal aery)
Medicine
null
82de2218-03e8-48e5-87d2-9a75c90d908d
von Willebrand disease is a defect of
Primary hemostasis
Secondary hemostasis
Clot stabilization and resorption
Generalized defects involving small vessels
0a
multi
Primary hemostasis: the formation of the platelet plug.Disruption of the endothelium exposes subendothelial von Willebrand factor (vWF) and collagen, which promote platelet adherence and activation. Activation of platelets results in a dramatic shape change as well as the release of secretory granules. Within minutes t...
Pathology
General pathology
0eab11e1-76bd-4293-9f36-ce0387d2302c
All true about sodium Thiopentone except -
It is intermediate acting barbiturates
It is cerebroprotective
It is agent of choice for narcoanalysis
It is contraindicated in acute intermittent porphyria
0a
multi
Thiopentone is ultrasho acting barbiturate. Thiopentone does not produce analgesia and may even produce antianalgesia by reducing the pain threshold. Thiopentone has rapid onset of action (within 30 s) due to high lipid solubility and high non ionized fraction (60%). And ultra-sho duration of action (within 20 mins) du...
Anaesthesia
Intravenous Anesthetic Agents
2ee18a5a-4a1a-4d24-80da-0a46c7c8467f
Which of the following antihypeensive inhibits vesicular uptake of NA -
Propranolol
Prazosin
Reserpine
Guanithidine
2c
single
Ans. is 'c' i.e., Reserpine o Reserpine inhibits vesicular uptake of NA, 5-HT & DA --) monoamines are gradually depleted and degraded by MAO.
Pharmacology
null
50d5b1e8-f467-439d-bb60-3a2755121569
Gastric emptying is decreased by all of the following EXCEPT:
Protein breakdown products
CCK
Enterogastric reflexes
Gastrin
3d
multi
Acidity of the chyme, hyper- or hypo-osmolarity of the duodenal contents, irritation of the duodenal mucosa, protein or fat breakdown products in duodenum are the factors sensed by the duodenal receptors. Gastric emptying will then be decreased, by a combination of neural and hormonal signals. Neural signals would be e...
Physiology
Gastrointestinal System
fc242d58-17a5-452d-bf1d-a0f3b19cd8ea
Cystic supratentorial tumor is?
Craniopharyngioma
Ependymoma
Medulloblastoma
None of the above
0a
multi
Ans. is 'a' i.e. Craniopharyngioma * Craniopharyngioma is supratentorial slow growing cystic tumor.Other options* Ependymoma can both supra and infratentorial.* Medulloblastoma is an infratentorial tumor.
Pathology
Central Nervous System
531d39e8-f020-4784-80a9-47cb27911006
Microbiologic studies on a gram-positive coccus isolated from a skin abscess demonstrate a positive catalase test and a positive coagulase test. This is most consistent with which of the following organisms?
S. aureus
S. epidermidis
S. pneumoniae
S. pyogenes
0a
single
All of the organisms listed are gram-positive cocci. The positive catalase test excludes the Streptococci, S. pyogenes, and S. pneumoniae. Of the Staphylococci, only S. aureus has a positive coagulase test. S. epidermidis and S. saprophyticus are coagulase-negative Staphylococci. Ref: Ray C.G., Ryan K.J. (2010). Chapte...
Microbiology
null
2805abda-9716-46fe-845f-a5a2364ed33d
True about incest is: Karnataka 11
Punishable under Sec. 294 IPC
Punishable under Sec. 377 IPC
Punishable under Sec. 304-A IPC
Not punishable in India
3d
multi
Ans. Not punishable in India
Forensic Medicine
null
3d6f8aeb-b9c9-4982-b59d-bdf2ea482412
Pneumocytes are cells found in epithelial lining of:
Alveoli
Bronchus
Trachea
Bronchioles
0a
single
PneumocytesTwo types of pneumocytes contribute to the maintenance of the alveoli of the lungsType I pneumocytes and Type II pneumocytes.These cells function to aid in gas exchange, secretion of pulmonary surfactant, and self-regeneration
Anatomy
null
0e1e2404-6588-4f2c-83b6-2406b5acef56
Which one of the following is not a feature of liver histology in Non cirrhotic poal fibrosis (NCPF) ?
Fibrosis in and around the poal tracts
Thrombosis of the medium and small poal vein branches
Non specific inflammatory cell infiltrates in the poal tracts
Bridging fibrosis
3d
multi
Ans. is 'd' i.e., Bridging fibrosisFibrosis bridging one poal tract to another (bridging fibrosis) is not seen.Pathology : o Non cirrhotic poal fibrosis is primarily a vascular disorder of the liver characterized by fibrous intimal thichening of the poal vein or its branches in patients with non cirrhotic protal hypeen...
Pathology
null
36430cc0-55c8-433d-b533-74635cae551e
Which of the following is a harmful: March 2009
Alpha paicle
Gamma paicle
Neutron
Electron
0a
single
Ans. A: Alpha Paicle The radiation one typically encounters is one of four types: alpha radiation, beta radiation, gamma radiation, and X-radiation. Neutron radiation is also encountered in nuclear power plants and high-altitude flight and emitted from some industrial radioactive sources. A Alpha radiation is a heavy, ...
Radiology
null
8c49ef42-3055-4fca-a613-58b668b11ca4
Drug of choice for treatment of leptospirosis is:
Penicillin
Ampicillin
Tetracycline
Doxycycline
0a
single
Penicillin is the drug of choice for treatment of leptospirosis. Other drugs used are tetracycline and doxycycline. Ref: Park 21st edition, page 267.
Social & Preventive Medicine
null
edd35a5c-3e7f-4814-bdaa-248f65500a05
A 42 year old paraplegic woman has a neurogenic bladder and requires an indwelling urinary catheter. She develops a urinary tract infection and is seen by a urologist, who orders abdominal x-rays and an intravenous pyelogram. The radiographic studies demonstrate a very large stone that fills and follows the contours of...
Calcium salts
Cholesterol
Cystine
Magnesium ammonium phosphate
3d
single
Staghorn calculi, such as described in the question, are associated with infection by urea-splitting bacteria (notably Proteus species) and are composed of magnesium ammonium phosphate (struvite). They are more common in women than men, and are far more common in patients requiring chronic bladder catheterisation. Calc...
Pathology
null
c0e07c80-b445-4bcb-a434-6d98134b3715
A depot contraceptive DMPA is to be given every
1 month
3 months
2 months
6 months
1b
single
null
Social & Preventive Medicine
null
035263a1-d47e-43b6-a32a-0e98c5373cac
Temporary and permanent removed by –
Boiling
Addition of lime
Permutit method
All
2c
multi
Permutit method (Base exchange process) can remove both permanent and temporary hardness.
Social & Preventive Medicine
null
102b4d33-8b93-4545-b03d-d2f266dee087
Fluoride ion acts as inhibitor of:
Enolase
Hexokinase
Cyt oxidase
Carbonic anhydrase
0a
single
null
Biochemistry
null
133d3f39-1358-4187-a52f-11fcd0d1c01d
Puerperal pyrexia is defined as a temperature of more than:
98.4 degree F
99 degree F
100.4 degree F
104 degree F
2c
single
A temperature of 38.0degC (100.4degF) or higher--in the puerperium. Causes Genital tract infection Breast engorgement Urinary infections Wound infection Perineal lacerations infection Respiratory complications Predisposing factors Home bih in unhygienic conditions, low socioeconomic status poor nutrition primiparity an...
Gynaecology & Obstetrics
Puerperium
fdbd7b3b-f26f-4d43-9680-6938763fea7e
CB 1 antagonist used in smoking cessation is ?
Naloxona
Rimonabant
Vareniloline
Bupripion
1b
single
Ans. is 'b' i.e., Rimonabant Rimonabant A selective cannabinoid receptor-1 (CB-1) antagonist which is being tried as antismoking and antiobesity drug.
Pharmacology
null
d0858be7-d1f3-4c51-89ef-d587726a4ccb
Which of the following is not true about the difference between congenital cataract surgery and senile cataract surgery?
Incidence of Posterior capsular opacification is higher
Incidence of glaucoma is higher
The energy used in phacoemulsification is higher.
The chances of refractive surprise is higher.
2c
multi
The energy used in phacoemulsification is lesser as compared to the senile cataract. Congenital Cataract Surgery Treatment of choice: Lens aspiration by manual SICS technique or by phaco-emucification technique. Lensectomy can be done in total cataract with retinal detachment or ROP or any congenital retinal condition ...
Ophthalmology
Cataract
5e2e301d-064c-4dad-9f90-23c99bf795f1
What is the ideal treatment for a 55-years-female with Simple hyperplasia of the endometrium with Atypia?
Simple hysterectomy
Medroxy progesterone acetate (MPA)
Levonorgesterol (LNG)
IUCD
0a
single
Management of Atypical Endometrial Hyperplasia: "Hysterectomy is the best treatment for women at any age with atypical endometrial hyperplasia because the risk of concurrent subclinical invasive disease is high." Williams Gynae 1st ed p 691 "In presence of atypia, response to progesterone therapy is poor and the relaps...
Gynaecology & Obstetrics
null
e866d20f-64b7-46ac-b3af-8a60a0afa66d
Ehrlich phenomenon is seen in
Myobacterium Tuberculosis
Proteus
Staphylococcus
Corynebacterium
3d
single
The difference between the amount of diphtheria toxin that will exactly neutralize one unit of antitoxin and that which, added to one unit of antitoxin, will leave one lethal dose free is greater than one lethal dose of toxin; i.e., it is necessary to add more than one lethal dose of toxin to a neutral mixture of toxin...
Microbiology
Bacteriology
a31ac0d9-7280-4cf2-bc8e-d6cc79d99650
"Boiler's notch" is suggestive of ?
Conductive Hearing Loss
Noise Induced Hearing Loss (NIHL)
Both 1 and 2
Normal Finding
1b
multi
Boiler notch/Acoustic dip is seen in Noise induced hearing loss NIHL Boiler notch at 4000Hz Notch is seen in BC curve AC curve notch are insignificant Maximum seen at 3000-6000Hz Sound causing maximum NIHL 2000-3000Hz Stereocilia of Outer hair cells are first to be affected
ENT
Otosclerosis
d2fd2211-e5fd-440d-bda4-9a3ea08a4423
A 40 year old woman presents with a three day history of irritation, pain, and watery discharge of her left ear. She has just returned from holiday, where she admits to using her towel, aificial nails, and ear buds to try to allete itching in her ear. What is the likely diagnosis?
Mastoiditis
Otitis Externa
ASOM
Trigeminal Neuralgia
1b
multi
Inflammation of the ear canal with or without infection is the charecteristic of acute otitis externa. If symptoms are recurrent or if they last longer than three months, the condition is classed as chronic otitis externa. Acute otitis externa can also be classified according to its cause. These are split into three ma...
ENT
null
2b9d2de0-da44-4e0f-ada2-8269b72da37b
Following anterior dislocation of the shoulder, apt develops weakness of flexion at the elbow and lack of sensation over the lateral aspect forearm; nerve injured is -
Radial nerve
Musculocutanous nerve
Axillary nerve
Ulnar nerve
1b
single
The most common complication of anterior dislocation of the shoulder is axillary (circumflex) nerve injury. There is consequent paralysis of the deltoid muscle, with a small area of anaesthesia at the lateral aspect of the upper arm. However, in this question, the sensation is lost on the lateral aspect of the forearm ...
Orthopaedics
null
bc2e0345-620e-49e9-96f4-549e39f27ffe
Heavy smoker for elective hernia repair, smoking should be stopped before how much period?
4 days
10 days
3-4 weeks
6-8 weeks
3d
single
Ans. is 'd' i.e., 6-8 weeksRef: Postgraduate anaesthesia p. 786'Limited prospective data suggest that cessation for at least 6-8 weeks preoperative is necessary to decrease the incidence of pulmonary complication."
Anaesthesia
null
c1a20480-6ddb-418e-afa5-6852e27cd7c4
A nerve injured in radical neck dissection leads to loss of sensation in medial side of the arm, nerve injured is:-
Long thoracic nerve
Thoracodorsal nerve
Dorsal scapular nerve
Medial cutaneous nerve of arm
3d
single
Nerve injured in radical neck dissection leads to loss of sensation in medial side of the arm, nerve injured is medial cutaneous nerve of arm. The medial cutaneous nerve of arm supplies the skin of the medial aspect of the arm. It is the smallest branch of the brachial plexus, and arises from the medial cord and contai...
Surgery
Neck
e7da1575-242d-4836-a00b-7540f64c600b
Inward flow of Na+ in hea leads to
Plateu phase
Action potential
Repolarization
No change
1b
single
Entry of Na ions into cardiac cell leads to depolarisation. (REF TEXTBOOK OF MEDICAL PHYSIOLOGY GEETHA N 2 EDITION, PAGE NO 52)
Physiology
General physiology
0e38d827-9260-4dfd-841a-3afbb5c7ed84
Apoplexy is: DNB 08
Learning disability
Insanity leading to commitment of a crime
Sudden onset of bleeding in the brain
Injury to the brain due to trauma
2c
single
Ans. Sudden onset of bleeding in the brain
Forensic Medicine
null
e829cf1b-7a3a-491c-bafd-b389f645f77f
A 17-year old male complains of recurrent episodes of cough, wheezing and shoness of breath paicularly at night for the last 3 days. His sibling has a history of similar symptoms. A Skin test with pollen produces immediate wheal and flare. The laboratory finding most consistent with his clinical findings would be
Neutrophilia
Cold agglutinins
Positive direct antiglobulin test
Eosinophilia
3d
single
Atopy is the major risk factor for asthma.Patients with asthma commonly suffer from other atopic diseases,paicularly allergic rhinitis and atopic dermatitis.Eosinophilic infiltration of airways along with peripheral eosinophilia is a characteristic feature seen in asthmatic patients.There will also be elevated total se...
Medicine
Respiratory system
ee046d27-151a-4ade-b323-80cf8e398406
HLA complex in humans is located on?
Long arm of chromosome 6
Short arm of chromosome 6
Short arm of chromosome 8
Long arm of chromosome 8
1b
single
Ans. b (Short arm of chromosome 6). (Ref Harrison's medicine 16th ed. 1930)MAJOR HISTOCOMPATIBILITY COMPLEX (MHC)# MHC is a gene cluster of various loci grouped together on a single locus.# The MHC of humans, or the HLA complex, is located on the short arm of chromosome 6 approximately 32 CM from the centromere.# The l...
Pathology
Immunity
760c3ba2-74a9-43d7-92b0-456b3db8dd41
With which of the following receptors theophylline has an antagonist interaction?
Histamine receptor
Bradykinin receptor
Adenoside receptor
Inidazoline receptor
2c
single
theophylline is an eg of methylxanthine the action of this identified as a) release of ca from sarcoplasmic reticulum b) inhibition of phosphodiesterase c)blockade of adenosine receptor ESSENTIALS OF MEDICAL PHARMACOLOGY SEVENTH EDITION KD TRIPATHI PG NO.226
Pharmacology
Respiratory system
e75d515d-ded7-43cf-bc59-0eb7d7ddc7f2
Prodrug of cetrizine is
Foxefenadone
Terfenadine
Hydroxyzine
Azelastine
2c
single
Ans. is 'c' i.e., Hydroxyzine Cetrizine is a metabolite of Hydroxyzine with marked affinity for peripheral HI receptors; penetrates brain poorly. It inhibits release of histamine and of cytotoxic mediators from platelets as well as eosinophil chemotaxis during secondary phase of allergic response. It is indicated in up...
Pharmacology
null
8612dcc6-0d41-4954-8332-d5347d5f6671
All the following are true of Craniopharyngioma except
Derived from Rathke's pouch
Contains epithelial cells
Present in sella or infra-sellar location
Causes visual disturbances
2c
multi
Answer is C (Present in sella or infrasellar location): Some of these lesions arise from the sella, but most are suprasellar Q (Not infra-sellar). They arise from near the pituitary stalk and commonly extend into the supra sellar cistern. Craniopharyngiomas arise from Rathke's pouch and constitute 3-5% of all intracran...
Medicine
null
052712f9-b299-4816-b6f3-d6e69a61d55c
Par boiling of paddy helps in retaining – a) Vitamin Cb) Vitamin Ac) Niacind) Thiamine
ab
cd
bd
ac
1b
single
null
Social & Preventive Medicine
null
7057e987-54ec-4fb7-891e-96e4c1c105a2
Characteristic feature of early congenital syphilis is:
Microcephaly
Saddle nose
Interstitial keratitis with saber skin
Vesicular rash with bulla over palms and soles
3d
single
D i.e. Vesicular rash with bulla over palms & soles
Skin
null
72fb8292-28d4-4042-a00c-11b9850f32d1
All of the following are true of pulmonary embolism except:
Sudden onset of pleuritic pain and hemoptysis and hypotension.
ECG shows evidence of acute left ventricular stress.
Pulmonary angiography is gold standard
CTPA is imaging modality of choice
1b
multi
Classic Findings in Pulmonary Embolism:- Right Hea strain and Acute Cor Pulmonale - sudden onset of pleuritic chest pain, hemoptysis and hypotension - Tall, peaked P waves in lead II (P pulmonale) - Right axis detion - Right bundle-branch block - S1Q3T3 pattern. On Xray :- Hampton's hump, Westermark sign (areas of rela...
Medicine
Thromboembolism and Fat Embolism Syndrome
c3ab2112-2831-4d5e-bf63-7309cfbaa6eb
A patient presented with pain in left eye associated with visual distrubance, also a history of blunt trauma to eye 4 month back, first investingation of choice is
Introcular tension
Ophthalmoscopy
Perimetry
Ultrasound
0a
single
A i.e. Intraocular tension This is a case of angle recession glaucoma
Ophthalmology
null
93197edf-91e9-4a0f-8c2b-7cb2958454b7
72 year old patient it comes with esophageal carcinoma in lower oesophagus. There are no distant metastasis and lymph node involvement. What is the preferred surgery
Transhiatal esophagectomy
Ivor Lewis esophagectomy
Endoscopic resection
McKeown esophagectomy
0a
single
null
Surgery
null
7e716644-3454-49ab-917c-93d57435265b
Not seen in the peripheral smear in plasmodium falciparum infection -
Accole
Maurer'sdot
Shuffners dots
Schizonts
2c
single
Schuffner&;s dot in the Rbc can be seen in P. vivax and P. Ovale infection Maurer&;s dot -falciparum Ziemman&;s dot- malariae (refer pgno:61 baveja 3 rd edition)
Microbiology
parasitology
d129f9ec-6087-4ca3-978c-a4e9dccbbc6b
Carina is situated at which level
T3
T4
T6
T9
1b
single
Carina is located at the bifurcation of trachea at lower border of T4.carina is the lower margin of lowest cailaginous ring that is a keel-shaped process curving downwards and backwards between the bronchi.The mucous membrane lining the area is highly sensitive and is origin of the protective cough reflex. It is visibl...
Anatomy
Head and neck
63903d5c-6620-4179-b783-d67380c6d354
Bromocriptine can be used in following conditions except
Hyperprolactinoma
Acromegaly
Parkinsonism
Diabetes insipudus
3d
multi
Refer KDT 7th/e Pg 239. Bromocripine is approved in diabetes mellitus not diabetes insipudus Bromocriptine is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease, hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes.
Pharmacology
Kidney
01611f13-d012-426b-89ec-2c01b439c369
Calcification of soft tissues without any distrubances of calcium metabolism is called
Inotrohic calcification
Monotrophic calcification
Dystrophic calcification
Calcium induced calcification
2c
multi
Ref,Robbins 9/e p65
Anatomy
General anatomy
278dfca5-6193-4e47-9e2e-d58941f7e272
. Treatment of choice in cold nodule of thyroid
Subtotal thyroidectomy
Wait and watch
I-131
Hemithyriodectomy
3d
single
null
Surgery
null
73036435-9c72-4701-bd0c-689823ff8258
Wavelength of Nd:Yag laser
1040 nm
1040 mm
1040 cm
1040 pm
0a
single
A i.e. 1040 nm
Ophthalmology
null
4c65cedd-af13-4807-ba05-c97455115e02
Least common organ affected in blast injury is -
Lung
Eardrum
Muscles
GIT damage
2c
single
Ans. is 'c' ie., Muscles * An explosion is a phenomenon resulting from sudden release of energy which is then dissipated by a blast wave, by translocation of objects, or by the generation of heat.* Injuries in explosion occur due to four factors:-1) Blast or shock wave# When an explosion occurs, the explosive material ...
Forensic Medicine
Injuries
506ed80f-1da0-4cea-8049-a58bdc371400
A 58-year-old postmenopausal woman on estrogen replacement complains of recent onset of spotting. A bimanual pelvic examination is unremarkable. Most likely diagnosis?
Cervical carcinoma
Cervical polyp
Dysfunctional uterine bleeding
Endometrial hyperplasia
3d
single
Any postmenopausal woman who has been on unopposed estrogen and who is now experiencing vaginal bleeding is suspect for either endometrial hyperplasia or endometrial cancer. Endometrial hyperplasia is the end result of prolonged estrogenic stimulation of the endometrial mucosa. Morphologic forms of hyperplasia include ...
Gynaecology & Obstetrics
Menopause and HRT
3befe139-cb58-47a0-a123-a236dc563349
Methods of introducing gene in target cells are all except
Electroporation
Transfection
Site directed recombination
FISH
3d
multi
Fluorescence in situ hybridization(FISH) is a cytogenetic technique that uses fluorescent probes that bind to only those pas of the chromosome with a high degree of sequence complementarity.
Biochemistry
Metabolism of nucleic acids
65f7eac4-e446-4417-a053-f3f81fae2140
Treatment of pleomorphic adenoma without facial nerve infiltration and limited to superficial lobe:
Superficial parotidectomy
Total parotidectomy
Parotidectomy followed by radiotherapy
Observation
0a
single
Pleomorphic adenoma: * Most common salivary gland tumor * Benign, painless tumor with no facial nerve involvement * Most common site - Parotid, Submandibular, Sublingual, minor salivary gland * Location: Infront, below and behind ear lobule * Pathology: Mixed tumor has both epithelial and mesenchymal component * Tumor ...
Surgery
Salivary Glands
b09b9437-2410-413d-a692-08b24e5efbcb
Post is not required in all of the following conditions except:
If adequate retention of core can be achieved by natural undercuts of crown
If there are horizontal cracks in the coronal portion of the teeth
When tooth is subjected to excursive occlusal stresses, that is, when there is presence of lateral stresses of bruxism or heavy incisal guidance
None
3d
multi
Conditions where post should not be given: Any sign of endodontic failures are evident, i.e. tooth exhibits: Poor apical seal and poor quality obturation Active inflammation Presence of fistula or sinus Tender on percussion If adequate retention of core can be achieved by natural undercuts of crown. If there are h...
Dental
null
2bdf8544-f059-4218-a0fe-abd58dec820c
Pearson's Coefficient of skewness is defined as:
(Mean-Mode) / SD
(Median-Mode) / SD
SD / (Mean - Mode)
SD / (Median -Mode)
0a
single
The coefficient used for checking the skewness of data, is called as the Karl Pearson coefficient, and is calculated as (Mean - Mode) S.D. Ref: Instant Medical Biostatistics, By Ranjan Das, Papri N. Das, 2009 Ane's Instant Medical Series, Page 41, 42.
Social & Preventive Medicine
null
129b2b80-810b-4c00-869e-9975e803e0c0
Stocker's line is seen a –
Pinguecula
Pterygium
Congenital Ocular Melanosis
Conjunctival epithelial melanosis
1b
single
Stocker's line is a line of iron deposition in the corneal epithelium seen adjacent to the head of the pterygium.
Ophthalmology
null
e2c81a04-9d13-4568-9b01-36c067992c91
Ovarian artery is a branch of-
Abdominal aorta
Renal artery
Superior mesenteric artery
Celiac trunk
0a
single
Ans. is 'a' i.e., Abdominal aorta * 'Ovarian artery is a branch of abdominal aorta'
Anatomy
Abdomen & Pelvis
0c265c8e-5783-4de5-8c32-5d9a7aea0ffb
Which of the following anti-angina drugs act by inhibition of long-chain 3-ketoacyl coenzyme A thiolase?
Trimetazidine
Ivabradine
Ranolazine
Nicorandil
0a
single
Trimetazidine Antianginal drug that act by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase enzyme. Reduced fatty acid metabolism and increased glucose metabolism in myocardium leading to a paial shift from FFA to glucose oxidation in the hea, which provides less ATP but requires less O2 and may there...
Pharmacology
CHF, Angina Pectoris and Myocardial Infarction
55242f21-9a5e-4a64-843a-b251e948328a
A previously healthy 58 years old man is admitted to the hospital because of an acute inferior myocardial infarction. Within several hours, he becomes oliguric and hypotensive (blood pressure is 90/60 mmHg). Insertion of a pulmonary artery (Swan-Ganz) catheter reveals the following pressures: pulmonary capillary wedge-...
Fluids
Digoxin
Dopamine
Intraaortic balloon counterpulsation
0a
multi
null
Medicine
null
cc2e4e9b-7c5e-4fa9-b86a-207105cfb251
Post treatment HCG levels, during the follow up of molar pregnancy evacuation, comes back to normal in:
3 weeks
6 weeks
9 weeks
12 weeks
2c
single
HCG follow up of vesicular mole: - weekly HCG estimation till negative (vesicular mole takes 9 weeks and paial mole takes 7 weeks) - weekly HCG till 3 more weeks - Once in a month for 6 months . Avoid pregnancy during this time. Use contraception, best being COCPs
Gynaecology & Obstetrics
Obstetrics
7e099b78-be54-4447-874c-232efa04763c
which of the following antidepressent can be safely used in elderly depresion
trazadone
miazapine
fluoxetine
phenelezine
1b
single
NaSSA * IMPOANCE Nor adrenergic and specific serotonergic antidepressant * MECHANISM * Alpha 2 adrenergic receptor antagonism=== increase serotonin and NA * 5HT2,3 antagonist============increase sleep and appetite * DRUGS miazapine * USE Elderly with depression * SIDE EFFECTS hyperlipidemia Ref. kaplon and aock, synops...
Psychiatry
Pharmacotherapy in psychiatry
a6ac4478-bd5f-41e6-9107-20c03f32bb4f
Most common psychiatric disorder in community is
Depression
Schizophrenia
Paranoid disorders
Obsessive compulsive neurosis
0a
single
(A) Depression # DEPRESSION is the most common psychiatric illness in India.> Neurotic depression is far common than psychotic depression.> Neurotic depression is followed by anxiety neurosis is prevalence.> This is in contrast to West, where anxiety neurosis is the commonest.
Psychiatry
Miscellaneous
c84c2cba-d366-40dc-80ae-2e6ed9c7b9a6
McBurney's point corresponds to which pa of appendix:
Tip
Base
Orifice
Mid poion
1b
single
Base
Anatomy
null
138478ef-51c8-487b-ac52-6f8e45cf9e2c
Muscle not supplied by median nerve REPEATED
Opponens pollicis
Abductor pollicis brevis
Extensor pollicis brevis
First lumbrical
0a
single
Opponens pollicis, abductor pollicis brevis and first lumbrical is supplied by the recurrent branch of median nerve in palm.Extensor pollicis brevis is supplied by the deep division of radial nerve in the forearm.B D Chaurasia 7th edition Page no: 182
Anatomy
Upper limb
59c0554b-a859-4a76-83b9-307ae14499cb
Thyroid malignancies appear on USG as
Hypoechoic
Anechoic
Hyperechoic
Isoechoic
0a
single
On sonography, thyroid tumors are solid,hypoechoic masses.
Radiology
ULTRASOUND
c1607548-8101-45f0-9d23-fc3ec936c485
Which micronutrient deficiency causes anemia?
Copper
Molybdenum
Selenium
Flurine
0a
single
Ans. is 'a' i.e., CopperCopper containing protein ceruloplasmin is necessary for transpo of iron in the Ferric form across membranesCopper is an integral component of ALA synthase, which is necessary for heme synthesisCopper helps in the uptake of iron across normoblasts
Biochemistry
null
6e0ea60e-0f54-4b6f-a0ff-ade78664e005
A 45-year-old female has a solitary gall stone 1.5 cm in size which was incidentally diagnosed by ultrasound. She has no symptom. What should be the best line of management?
Cholecystectomy only, if she develops biliary colic
Lap cholecystectomy immediately
Lap cholecystectomy even if she is asymptomatic after 2 months
Open cholecystectomy even if she is asymptomatic after 2 months
0a
multi
Cholecystectomy only if she develops biliary colic * Symptomatic gallstones are the main indication for cholecystectomy. * Absolute contraindications for the procedure are uncontrolled coagulopathy and end-stage liver disease.
Surgery
null
cb5482dd-a27f-417c-b996-e1e07be1a911
Which of the following causes pseudotumour cerebrii -
Chronic subdural hematoma
Cerebellar tumours
Hypervitaminosis A
Cerebral hemangiomas
2c
single
null
Medicine
null
f7e9a66a-7b20-4412-8995-8faeca2117c9
Which one of the following is not seen in pheochromocytoma
Hypeension
Episodic palpitations
Weight loss
Diarrhea
3d
single
Refer Robbins page no 1135 The dominant clinical manifestation of pheochromocytoma is hypeension observed in 90 percnt of patients.Approximately two thirds of patients with hypeension demonstrate paroxysmal episodes which are described as an abrupt precipitation elevation in blood pressure
Anatomy
Endocrinology
e57f59e2-dce5-44ee-b6db-a0bb8f4676bf
Most common site of venous thrombosis: March 2013
Veins of upper extremity
Veins of lower extremity
Dural sinus
Poal vein
1b
single
Ans. B i.e. Veins of lower extremity Commoner sites of venous thrombosis includes deep vein in the lower extremity below the knee and superficial saphenous, hepatic and renal veins; dural sinuses.
Pathology
null
634cffe7-ac84-46cb-bd3f-16bb0f0d03a5
Duffy antigen is present in:
P. Falciparum
P. Ovale
P. Vivax
P. Malariae
2c
single
Ans. (c) P. VivaxRef: Microbiology by Ananthanarayan and Paniker 8th ed. 1694* Duffy antigen/chemokine receptor (DARC) also known as CD234, is a protein that in humans is encoded by DARC gene.* The Duffy antigen is located on the surface of red blood cells.* The Duffy antigen protein is also the receptor for the human ...
Microbiology
Virology
82779476-eeab-46e0-8539-9ff48ef9e238
Hea failure cells are?
polymorphonuclear cells
Steam cells
Macrophages
Fibroblasts
2c
single
Breakdown of red cells and hemoglobin leads to the appearance of hemosiderin-laden alveolar macrophages-- so-called hea failure cells--that reflect previous episodes of pulmonary edema. (Robbins Basic Pathology,9th edition,pg no.367)
Pathology
Cardiovascular system
ea5bee84-af8c-496d-afeb-3049d6bd3841
Prolactinoma in pregnancy, all are true except:
Most common pituitary tumor but rarely symptomatic
Increase in prolactin levels worse prognosis
Macroadenoma> 1 cm is associated with bad prognosis
Regular visual checkup
1b
multi
Prolactinoma pituitary adenoma Prlactin level is >100ng/dl most are microadenoma<1cm diameter macroadenoma has bad prognosis visual field examination is essential to detect any compression effect on the optic nerves D.C.DUTTA&;S TEXTBOOK OF GYNECOLOGY,Pg no:464,6th edition
Gynaecology & Obstetrics
Medical, surgical and gynaecological illness complicating pregnancy
a570c951-1097-412d-a01c-47a51a253cab
Not true about red degeneration of myomas is :
It occurs commonly during pregnancy
Immediate surgical intervention is needed
Due to interference with blood supply
Treated with analgesics
1b
multi
Ans. is b i.e. Immediate Surgical intervention is required Lets see each option one by one. Red Degeneration of fibroid commonly occurs during pregnancy. (Option "a" is thus correct) The pathogenesis of fibroid is obscure but the initial change appears to be one of sub acute necrosis which is presembly due to an interf...
Gynaecology & Obstetrics
null
9feced4c-6405-4dc4-9f16-bf306c596807
Stuart's medium is a transport media for
Streptococcus
Neisseria
Vibrio
Shigella
1b
single
Stuart's and Amies medium are transport media for Neisseria.
Microbiology
null
4e8a9141-a95e-4333-9d31-48a865005776
Which of following is not seen in nephritic syndrome:
Edema
Hematuria
Hypertension
Hypocholesterolemia
3d
single
d. Hypocholesterolemia(Ref: Nelson's 20/e p 2521-2528, Ghai 8/e p 477-482)Features of nephritic syndrome are: Hematuria and RBC casts, Nephritic range Proteinuria (<3.5g/day), hence edema is present, Hypertension, Uremia and Oliguria.
Pediatrics
Kidney
8ca00678-1009-45dd-8419-a32a0735505c
Fulminant hepatic failure can be caused by
Halothane
Isoflurane
Nitrous oxide
Phenobarbitone
0a
single
The first modern halogenated volatile anesthetic, halothane, was introduced in 1955. Clinical exposure to halothane is associated with two distinct types of hepatic injury. Subclinical hepatotoxicity occurs in 20% of adults who receive halothane. It is characterized by mild postoperative elevations in alanine aminotran...
Anaesthesia
Fundamental concepts
2b6dc1b9-4f42-4d0c-8a58-838cfa5a440b
Hartnup disease can present with:
Pellagra like symptoms
Nephrolithiasis
Protein intolerance
Microcephaly
0a
single
Ans. (a) Pellagra like symptomsRef: Harrisons 20th ed. P 3021Hartnup Disease* It is an AR condition, mainly seen due to defect in the transport of tryptophan and other neutral amino acids from the renal tubules and intestine* Molecular defect: SLC6A19 gene (encode transporter protein of these amino acid)Clinical Featur...
Biochemistry
Proteins and Amino Acids
19ad715f-df5e-40c3-8483-b48e602ab0fe
A 8-year-old boy presents with petechiae, azotemic oliguria and altered sensorium, in casualty. There is a history of diarrhoea for the past 5 days. The clinical diagnosis is –
Acute prophyria
Idiopathic thrombocytopenic purpura
H.S. purpura
H.U.S.
3d
single
Hemolytic uremic syndrome HUS is characterized by the triad of - Anaemia (microangiopathic hemolytic anaemia) Renal failure (microangiopathy of kidney involving glomerular capillaries and arterioles). Thrombocytopenia (due to platelet destruction) HUS is common in children under 2 years of age. (But may also occu...
Pediatrics
null
c4443260-8197-4f9a-9882-f7f1b4835347
True about Hb dissociation curve:
Acidosis shifts O2 dissociation curve to right
Increased CO2 shifts the curve to left
Hypoxia shifts curve to left
2,3 DPG has no effect on curve
0a
multi
Oxygen-hemoglobin dissociation curve is shifted to right in the following conditions:  Decrease in partial pressure of oxygen.  Increase in partial pressure of carbon dioxide (Bohr effect). Increase in hydrogen ion concentration and decrease in pH (acidity).  Increased body temperature.  Excess of 2,3-diphosphoglycera...
Physiology
null
a5ffd718-246b-4224-b2e4-5c8fb7d73ae6
Regarding the antibacterial action of gentamicin, which of the following statements is most accurate?
Efficacy is directly propoionate to the time that the plasma level of the drug is greater than the minimal inhibitory concentration
Gentamicin continues to exe antibacterial effects even after plasma levels decrease below detectable range
Antibacterial activity is often reduced by the presence of an inhibitor of cell wall synthesis
The antibacterial action of gentamicin is time dependent
2c
multi
(Ref:Katzung 10/e p756, 757) Aminoglycosides show concentration dependenbt killing and prolonged post antibiotic effect. For details, refer to text.
Pharmacology
Other topics and Adverse effects