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1. Introduction {#sec1-sensors-20-00472}
===============
The relationship between water contents in the plant and yield has been well established \[[@B1-sensors-20-00472],[@B2-sensors-20-00472]\]. The use of standardized parameters based on physiological thresholds that lead to photosynthetic impairment if surpassed h... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Target condition being diagnosed {#Sec2}
--------------------------------
Despite successful vaccination programmes, meningococcal disease (MD) remains a leading infectious cause of septicaemia and death in children worldwide \[[@CR1]--[@CR5]\]. Early diagnosis of MD significantly improv... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Haptoglobin (Hp) is a plasma protein that binds extracorpuscular hemoglobin (Hb) and prevents it from inflicting iron‐mediated oxidative tissue damage.^[@b1]^ The Hp gene has 2 major alleles, Hp1 and Hp2. Of these, the latter is a mutated version of the former and unique to humans.^[@b2]^ Thi... | {
"pile_set_name": "PubMed Central"
} |
Cortical oscillations in the beta frequency band (15 to 35 Hz) are thought to play a central role in cortical processing of information related to movement and cognition ([@r1], [@r2]). In Parkinson's disease (PD), cortical beta oscillations become abnormally synchronized through their interaction with the dopamine-dep... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
Anti-N-methyl-[d]{.smallcaps}-aspartate receptor encephalitis (ANMDARE) is a disorder presenting with subacute onset of seizures, psychosis, memory and language deficits, abnormal movements, and breathing and autonomic disturbances [@bb0005], [@bb0010]. Although initially ident... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
The Istituti Fisioterapici Ospitalieri (IFO) comprise two scientific institutes: the Regina Elena National Cancer Institute (IRE) & the Dermatological Institute S. Gallicano (ISG), both located in Rome, Lazio, Italy. Despite the overwhelming challenges the entire healthcare community face... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
The ocean acts as a buffer against global warming^[@CR1]^. However, understanding all processes and fluxes that lead to carbon sequestration is very complex and acts at multiple scales, from genes to ecosystems *via* physiological processes^[@CR2],[@CR3]^. In particular, the ecosystem... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
According to the statistical report released from Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2015, thirty out of every 100,000 people in the general population suffered from a primary intracranial tumor requiring craniotomy for tumor resection. Gliom... | {
"pile_set_name": "PubMed Central"
} |
The Mediterranean region has unquestionably played a central role in human history, partly deriving from the navigable nature of the sea that connects southern Europe, western Asia, and North Africa. This unique setting has led to its being one of the most important and dynamic areas throughout prehistory.
The period ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Over the course of a chronic illness, patients face challenges on many fronts. On a basic level, they endeavor to understand what is happening to them and deal with their illness. This may include navigating the health care system and understanding their medication regimen. They interact with... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Enhancing the grain yield potential of wheat is a key focus of wheat breeders. Grain yield is the product of various yield components. Wheat grain yield per unit area is the product of grain yield per spike (GYS) and the number of spikes per unit area. The latter depends on sowing density... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Introduction {#S0001}
============
Dry eye disease (DED) is a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film, and accompanied by ocular symptoms.[@CIT0001] Being the most common reason for seeking medical eye care, DED is a common public health problem, with the pr... | {
"pile_set_name": "PubMed Central"
} |
Protocol
========
To guarantee high quality and reproducibility, we recommend the use of Standard Operating Procedures (SOP). In this video, published SOPs as developed and used in our laboratory are applied. ^1^
1. Middle Cerebral Artery Occlusion
-----------------------------------
1. Mic... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Although the CA2 region was first described by Lorente de Nó in 1934^[@R8]^ relatively little is known about its functional properties and behavioral role. To examine the importance of this region, we generated a transgenic mouse line (*Amigo2-Cre*) that expresses Cre recombinase predominantly in CA2 pyramidal neurons ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Water is a seemingly simple yet practically complex liquid with extraordinary phase behavior, which enables many of life's intricacies. While water is possibly the most studied liquid, there remain many areas where its behavior is still mysterious^[@CR1]^. A prime example for this is ... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction {#sec1}
==================
The technique of single-crystal X-ray diffraction enables the routine and precise structure determination of biological macromolecules at high resolution (Blow, 2002[@bb9]; Rupp, 2010[@bb51]). It has been applied extensively to proteins, DNA and RNA, with the PDB recently ... | {
"pile_set_name": "PubMed Central"
} |
The content published in Cureus is the result of clinical experience and/or research by independent individuals or organizations. Cureus is not responsible for the scientific accuracy or reliability of data or conclusions published herein. All content published within Cureus is intended only for educational, research a... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-nanomaterials-09-01643}
===============
The wide-ranging use of antibiotics, dyes, and heavy metals and their reckless release in water has drawn intensive attention due to their toxicity and non-biodegradability \[[@B1-nanomaterials-09-01643],[@B2-nanomaterials-09-01643],[@B3-nanomaterials-09-0... | {
"pile_set_name": "PubMed Central"
} |
BoNTs are a family of bacterial toxins, classified as one of the six most dangerous potential bioterrorism agents (Category A and Tier 1 select agent in the United States)[@b1]. They are also widely used to treat a growing list of medical conditions[@b2][@b3], including muscle spasms, chronic pain, overactive bladders,... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-life-06-00037}
===============
Halophilic microorganisms thrive in the briny waters of salt lakes and evaporative solar salterns \[[@B1-life-06-00037]\]. Saturated salinity, from 25%--35%, presents osmotic obstacles for life, but we see representatives from all three domains thriving in these co... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Hematopoietic stem cells (HSC) reside in a special bone marrow (BM) niche, which regulates their localization, self-renewal and differentiation. Studies have identified several major cell types of the niche, including mesenchymal stem cells (MSC), osteolineage cells (OLC), adipocytes and vasc... | {
"pile_set_name": "PubMed Central"
} |
Sepsis and septic shock are the leading causes of death in intensive care units (ICUs) and have significant mortality rates (as high as 60%) and health-care cost burdens (40% of total ICU expenditures)[@b1]. Recent epidemiological studies have shown that approximately 47% of ICU patients with severe sepsis have positiv... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Atherosclerosis is generally considered to be positively associated with hypertension^[@CR1]^. A single nucleotide polymorphism (SNP) (rs3782886) in breast cancer suppressor BRCA1**-**related associated protein (BRAP) has been associated with the risk of developing myocardial infarcti... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Praziquantel (PZQ) is virtually the sole treatment regimen for Schistosomiasis in sub-Saharan Africa \[[@CR1]\]. This oral schistosomicidal agent is constituted of a racemate mixture, with activity both in vivo and in vitro \[[@CR2], [@CR3]\]. Evidence from studies conducted on *Schistoso... | {
"pile_set_name": "PubMed Central"
} |
Main {#Sec1}
====
RNA interference (RNAi) is a natural cellular process that regulates gene expression and provides an innate defence mechanism against invading viruses and transposable elements^[@CR1]^. The finding that dsRNA initiates RNAi was among the most significant recent contributions to cell biology^[@CR2]^, ... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Accurate and timely diagnosis of malaria infections is a critical part of case management in malaria control programmes aiming to reduce malaria morbidity and mortality. Sensitive and effective detection of infected individuals also plays a vital role in areas where transmission has been reduced ... | {
"pile_set_name": "PubMed Central"
} |
This article was republished on November 20, 2013, to replace an incorrectly published version. Please download this article again to view the correct version.
**Competing Interests:**No competing interests declared.
| {
"pile_set_name": "PubMed Central"
} |
Sakamoto S, Inoue H, Kaneko MK, et al. Generation and evaluation of a chimeric antibody against coxsackievirus and adenovirus receptor for cancer therapy. Cancer Sci. 2019;110:3595--3602. 10.1111/cas.14196
Sakamoto and Inoue contributed equally to this work.
ADCC
: antibody‐dependent cellular cytotoxicity
CAR
: ... | {
"pile_set_name": "PubMed Central"
} |
Acute ischemic stroke patients with large established infarction treated with reperfusion therapy are more likely to have a poor functional outcome and reperfusion edema or haemorrhage.^[@R1]^ The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) score is a 10-item score assessing brain parenchyma hypode... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Protein interactions take place physically between interface residues of two complementary proteins. Studies focusing on protein interfaces have revealed that binding energies are not uniformly distributed along the protein interfaces. Instead, there are certain critical residues called 'hot ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
*Reputations*, information that signals the potential cooperativeness of others (Tennie et al., [@B62]), are known to facilitate cooperation (Milinski et al., [@B41]; Feinberg et al., [@B22]). Due to their impact, however, reputations are subject to distortion (e.g., spreading lies or g... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
*Fritillaria cirrhosa*, which belongs to the family Lilliaceae, is primarily distributed in the southwestern China. Bulbs of*Fritillaria cirrhosa* (BFC) have long been used both for food and folk medicine in many Asian countries \[[@B1]\]. The materials from wild collections can... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Inbreeding, defined as the mating between two related individuals, increases the occurrence of homozygous deleterious alleles. The loss of heterozygosity leads to a decrease in the fitness of offspring, known as inbreeding depression [@pone.0095963-Charlesworth1] although inbreeding may... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1}
============
Silicosis is considered as one of the serious types of pneumoconiosis and a potentially fatal occupational fibrotic lung disease \[[@B1]\], which is highly prevalent in developing countries, especially in China, South Africa, and Brazil \[[@B2]\]. Accumulating evidence shows that sili... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
More than two-thirds of pregnant women exceed the Institute of Medicine (IOM) 2009 gestational weight gain (GWG) recommendations \[[@ref1]\]. According to weight management guidelines for obesity treatment \[[@ref2]\], prenatal care should provide an ideal clinical framework for treatment del... | {
"pile_set_name": "PubMed Central"
} |
Ghazvini K, Karbalaei M, Kianifar H, Keikha M. The first report of *Streptococcus pluranimalium* infection from Iran: A case report and literature review. Clin Case Rep. 2019;7:1858--1862. 10.1002/ccr3.2374
1. INTRODUCTION {#ccr32374-sec-0001}
===============
*Streptococcus pluranimalium* is unusual streptococcal spe... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Sepsis remains a major cause of mortality, and there is recent data to suggest that the incidence of sepsis is increasing \[[@CR1]\]. Treatment options remain limited to early antibiotic therapy, resuscitation and aggressive support of failing organ systems. Multiorgan dysfunction syndrom... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Chronic hypoxia is an important factor contributing to the near-irreversibility of hypoxia-induced pulmonary hypertension (HPH), a condition characterized by structural remodeling of small pulmonary arteries (PAs). These important morphological changes are characterized by an abnormal increas... | {
"pile_set_name": "PubMed Central"
} |
Passive smoking is the inhalation of second-hand smoke (SHS) by persons other than the "active" tobacco smoker. This exposure to SHS may cause disease, disability, and death \[[@b1-ophrp-10-049]\]. Passive smoking has been shown to be associated with the same diseases as active smoking (such as cardiovascular diseases,... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Among trace elements, zinc (Zn) is a micronutrient influencing growth and affecting the development and integrity of the immune system \[[@R1]\]. Also, it has important roles in physiological functions of the human body. It has a critical role for the function of over 300 enzymes \[[@R2... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
School safety is fundamental to fostering positive short and long-term outcomes for children, including positive mental health, school connectedness, student retention and academic success (Battistich, Schaps, & Wilson, [@CR6]; Horner et al., [@CR37]). We define a safe school as one that ... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction
================
In Sri Lanka, alcohol use is a growing public health issue \[[@b1-ijerph-06-02408]--[@b3-ijerph-06-02408]\], and, because it is a predominantly male habit there, alcohol use disproportionately harms Sri Lankan males. Adolescents and young adults in the country are highly vulnerable to... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Lung cancer remains a major health problem worldwide. In 2012 lung cancer was the most commonly diagnosed cancer worldwide making up 13.0% of the total incidence of cancer. It was also the most common cause of death from cancer worldwide, accounting for nearly one in five cancer... | {
"pile_set_name": "PubMed Central"
} |
Related literature {#sec1}
====================
For the isostructural compound 5-chloro-2-hydroxybenzaldehyde 4-ethylthiosemicarbazone, see: Lo *et al.* (2011[@bb1])
Experimental {#sec2}
==============
{#sec2.1}
### Crystal data {#sec2.1.1}
C~10~H~12~BrN~3~OS*M* *~r~* = 302.20Monoclinic,*a* = 22.040 (... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
INTRODUCTION {#s1}
============
Epithelial ovarian cancer (EOC) represents the leading cause of death in gynaecological malignancies \[[@R1]\]. EOC progresses mainly through extensive intraperitoneal and/or retroperitoneal (lymphatic) tumour spread, while distant metastases are rarely seen \[[@R2]\]. So far, the biolo... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Radical cystectomy (RC) remains the standard of care for local treatment of non metastatic muscle invasive bladder cancer (MIBC). However, cancer specific survival is approximately 50% depending on the presence of extravesical extension and/or lymph nodes metastases \[[@bib1]\].... | {
"pile_set_name": "PubMed Central"
} |
CASE REPORT
===========
A 36-year-old man visited the emergency department. He had suffered from a sudden onset of chest pain, headache, palpitation, and dizziness. His pulse was regular, bounding, and at a rate of 119 per minute, and his blood pressure was at 190/120 mmHg. Electrocardiography and echocardiography wer... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The nucleus accumbens (NAc) is a forebrain structure that regulates the vigor of reward-seeking. Its excitatory inputs likely encode motivational states and the presence of reward-associated cues (Mannella et al., [@B33]). For example, paraventricular thalamic (PVT) input regulates food... | {
"pile_set_name": "PubMed Central"
} |
**Correction to: BMC Biol**
**https://doi.org/10.1186/s12915-018-0606-4**
Upon publication of the original article, \[[@CR1]\], the authors noticed that the first authors' affiliation contained an error. In the first affiliation it reads "Queensland Brian Institute", whereas it should in fact be "Queensland Brain Ins... | {
"pile_set_name": "PubMed Central"
} |
Several recent reports point to enterovirus (EV) infections as key environmental triggers of type 1 diabetes (T1D)[@b1][@b2][@b3][@b4][@b5][@b6][@b7]. Conclusions are based on multiple proofs that include the histopathologic detection of EV antigens/genome in the islets of Langerhans of diabetics at different stages of... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
The detection and classification of voltage deflections in extracellular recordings caused by action potentials of neurons - called spikes - is known as spike sorting. It is necessary if single neuronal activities must be resolved from multi-neuronal firing activity. The assignment of... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S1}
============
A feature of almost all cancers is their ability to escape from the immune system. This process is called immuno-editing and is composed of three different steps: elimination, equilibrium, and escape. During the elimination phase, the immune system recognizes the antigens expressed by t... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Viruses are obligatory parasites that critically rely on their ability to transmit their genome from infected to uninfected host organisms. Being an inert particle, viruses have successfully evolved to exploit the behavior and physiology of their host. Viral infection induces the activation o... | {
"pile_set_name": "PubMed Central"
} |
###### Summary box
What is already known about this subject?
=========================================
1. Current treatment of acute gastroenteritis as recommended by the WHO includes the use of oral rehydration solution and zinc.
2. Studies carried out on racecadotril in children have proved its efficacy in reduc... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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Introduction {#sec1}
============
Mesoporous semiconductor oxide electrodes are used in different applications including electrochemical sensing, electrochromic devices and photoelectrochemical generation of fuels or electrical energy.^[@ref1]−[@ref5]^ All these applications rely on the external manipulation or tracki... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Most coaches and professionals linked to sports teams agree on the importance of both an adequate climate and good social relations, and the high perception of skill among team members in order to optimize group efficacy. Thus, many expert investigators in group dynamics have identified cohes... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
There is an established literature on gender differences in humor perception and humor styles. Men have been noted to prefer humor that has sexual or aggressive themes whereas women appear to prefer neutral or absurd humor ([@B1]). Whereas earlier studies showed that sexist humor (i.e., humor... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Rabies virus (RABV) is a prototypical member of the *Lyssavirus* genus of the *Rhabdoviridae* family, and the causative agent of rabies. Rabies is associated with severe neurological symptoms and high mortality rate, causing more than 50,000 human deaths annually, mainly in Asia and Afr... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Postpartum depression (PD) is one of the commonest psychological problems to affect postpartum women\'s health. Its prevalence rate worldwide was reported to be 11.9% and a higher rate of developing countries.^\[[@R1],[@R2]\]^ PD could develop symptoms as depressed emotion, fatigue, and... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
After the completion of the Human Genome Project \[[@CR1]\] and a successful case-control experiment in identifying age-related markers using single-nucleotide polymorphism (SNP) \[[@CR2]\], the number of genome-wide association study (GWAS) has been rising exponentially \[[@CR3]\]. GWAS ... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Pregnancy in a rudimentary noncommunicating uterine horn has already been described in the literature.^[@B1]--[@B8]^ Only 9 cases have been reported of a placenta accreta in a pregnant rudimentary uterine horn, but this situation led to hemorrhagic rupture of the uterus in 8 women.^[@B1],[@B3... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S1}
============
Disulfide bonds between pairs of cysteines contribute importantly to the folding and stability of many proteins. In bacteria, this advantageous modification is generally limited to proteins that are exported to the cell envelope or beyond. Many proteins involved in bacterial virulence (... | {
"pile_set_name": "PubMed Central"
} |
1. INTRODUCTION {#sec1-1}
===============
Worldwide, cervical cancer is the third most common cancer among women and the second most common cause of death, with 300,000 deaths per year ([@ref1]). PAP test is cheap, simple and most commonly used technique for cervical cancer and preinvasive cervical lesions screening. ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Humans possess robust metacognitive capacities to evaluate their performance on various tasks and make predictions about how such performance might alter in the future ([@niw018-B54]; [@niw018-B50]; [@niw018-B42]). Metacognitive evaluations are often studied by eliciting confidence judgments.... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
It is particularly challenging to provide policy-relevant information on women in the area of substance use and misuse, as the topic covers such broad territory. Problem substance use has been found to arise from a complex interplay of biological, genetic, psychological, social, cultural, relatio... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Atherosclerosis is a highly prevalent chronic inflammatory disorder that causes extensive mortality \[[@b1-medscimonit-25-8820]\], but the details of the underlying mechanism are unknown. In recent decades, accumulating evidence has revealed the essential regulatory role played by inflammation th... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the manuscript and its Supporting Information files.
Introduction {#sec001}
============
Swans are among the largest existing flying birds of the waterfowl family Anatidae. They are represented around the world (except in Africa and Antarctica) by six species from the genus *Cygnus*: four... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
South Africa, a land of stark contrasts, contains a diverse natural beauty that can easily be compared with some of the world's most majestic outdoor scenes. One of the new seven wonders of the natural world, Table Mountain, parades its splendour to the capital of South Africa, Cape Tow... | {
"pile_set_name": "PubMed Central"
} |
[^1]: **Session:** 167. Preclinical Study with New Antibiotics and Antifungals
*Friday, October 6, 2017: 12:30 PM*
| {
"pile_set_name": "PubMed Central"
} |
The management of trauma and other orthopedic diseases has progressed by leaps and bounds during the last 40 years. Similarly, the cost of treatment has increased proportionately with the advent of joint replacement and of course costly trauma implants. India is a land of contrasts where there are 5-star hospital treat... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-metabolites-07-00038}
===============
Duchene muscular dystrophy (DMD) is a neuromuscular disorder characterized by progressive loss of muscle mass that renders the mobility of its victims to wheelchair before the age of 12 \[[@B1-metabolites-07-00038]\]. Genetically, X-linked Duchenne muscular ... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
According to the provisions of the current European Medical Device Directive 93/42/EEC \[[@CR1], [@CR2]\] and the new European Medical Device Regulation (applicable as from May 2020) \[[@CR3]\], each manufacturer of medical devices has to set up a comprehensive system in order to identify... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
Introduction {#S1}
============
Fruits and vegetables are known to have high nutrient content, making them the basis of a healthy diet. Many of these foods can be eaten raw, and although this represents a practical advantage, it also makes them notoriously relevant to foodborne illnesses. *Salmonella enterica* is one ... | {
"pile_set_name": "PubMed Central"
} |
Erratum {#Sec1}
=======
During production of the original article \[[@CR1]\], a document supplied by the author containing a set of further corrections to the manuscript was overlooked. The article therefore published containing a number of errors which are detailed here.
The publisher would like to apologise for the... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
The way science is done or everyday practice of science is a major theme of Fred Grinnell\'s most recent work. The author presents a critique of the linear model of science followed by many scientists and its failure to represent how scientists really work. It is not a surprising observation ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
For people leaving homeless or women's shelters, the transition to community living can be challenging. Because much has to be arranged during this stressful time, people are often in need of practical and emotional support. They can no longer utilize shelter services, which are gener... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
} |
The measurement of cognitive functioning via neuropsychological (NP) testing is an important component of assessment after mild traumatic brain injury (mTBI), also known as concussion. A consensus statement on concussion in sport \[[@B1]\] concluded that such testing provides valuable information when evaluating a pers... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Despite advances in care, morbidity following traumatic brain injury (TBI) remains high ( [@nlw045-B1] , [@nlw045-B2] ). Following the primary direct mechanical injury to brain parenchyma, important secondary injuries develop over hours to days from multiple addressable mechanisms including h... | {
"pile_set_name": "PubMed Central"
} |
Pediatric intestinal failure (IF), as a result of short bowel syndrome (SBS) or gastrointestinal motility disorders, is a condition characterized by insufficient bowel function to maintain hydration and nutrient absorption for growth and development[@b1][@b2]. IF-associated liver disease (IFALD) is a serious complicati... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
*Fasciola gigantica* and *Fasciola hepatica* are omnipresent agents of a zoonotic parasitic disease, fascioliasis, which continues to be a major health burden on animals and humans. Fascioliasis can adversely affect the sustainability of the farm animal industry \[[@CR1]\]. The annual glo... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
With the increasing popularity in seeking complementary and alternative medicine (CAM) as a healthcare service, the prevalent use of herbal medicine as part of treatment is inevitable. Along with the rapid growth in consumption comes the pressing question on the safety of herbal... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The extract of *Colchicum autumnale*, which is more commonly known as autumn crocus, wild saffron, naked lady, or any of several other names, has been used in the therapy of gout for more than 15 centuries.[@b1-ijn-6-2697] At present, it is still in clinical use for the treatment of gout, as ... | {
"pile_set_name": "PubMed Central"
} |
I[ntroduction]{.smallcaps} {#sec1-1}
==========================
The neonatal intensive care unit (NICU) is a specialized care unit that treats premature and medically fragile newborns and infants. Advancements in medical technology, focused-training of skilled medical personnel, and the establishment of critical care ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
The use of combined modality treatment, including surgery, chemotherapy, and radiation, has resulted in increased disease control in locally-advanced head and neck cancer (HNC) \[[@CR1]\], but improved disease control occurs at the expense of increased acute and late effects from ther... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
============
^131^I-NaI has been used very effectively over several years for both the diagnosis and therapy of differentiated thyroid carcinoma (DTC). ^131^I whole body scintigraphy has been used for detection of remnant, residual as well as metastatic disease in patients of DTC. Though highly ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
NK cells represent a subset of lymphoid cells that are components of innate immunity acting as first line of defense against viral infection and other pathogens, and in the early cellular transformation and tumor surveillance^[@CR1]^. The functions of NK cells are partly regulated by ... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .890}
| {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Arising from notochord remnants such as the clivus, retropharyngeal space, and the ventral part of the cranio-vertebral junction (CVJ), chordoma has been considered a clinically malignant tumor because of its active biological nature. Maximal resection of the tumor is required because these t... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Pulmonary fibrosis can result from a variety of causes, including lung injury, environmental particle and toxin inhalation, chemotherapy, systemic autoimmune diseases, or as an idiopathic entity in form of idiopathic interstitial pneumonias (IIP) [@pone.0002142-Kim1]--[@pone.0002142-Mar... | {
"pile_set_name": "PubMed Central"
} |
Pancreaticoduodenectomy (PD) remains the standard surgical treatment for resectable peri-ampullary tumors. The first PD operation was reported by Codavilli in 1898 in a patient with an epithelioma of the pancreas, but the patient died from cachexia on the 21^st^ post-operative day.\[[@CIT1]\] In 1946, Whipple described... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1}
============
Stable integration of retroviral vectors encompassing a therapeutic transgene enables gene correction of severe blood and immune disorders. Over the past 25 years, murine leukemia virus (MLV)-based vectors have shown therapeutic benefit in gene therapy studies for primary immunodefici... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
RIS, structurally, a benzisoxazole derivative, is one of the most frequently prescribed atypical antipsychotics in the management of schizophrenia, mood disorders, and autism \[[@B1]\]. Its mechanism of action is not entirely clear. Although the use of atypical antipsychotic dru... | {
"pile_set_name": "PubMed Central"
} |
Foodborne illness resulting from consumption of food contaminated with pathogenic bacteria has been of vital concern to public health. Consumers today are increasingly concerned about chemical preservatives in food and tend to choose food products that are natural, safe and with multi-health benefits\[[@ref1][@ref2][@r... | {
"pile_set_name": "PubMed Central"
} |
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