Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Differential expression of the MAD2, BUB1 and HSP27 genes in Barrett's oesophagus-their association with aneuploidy and neoplastic progression. | Chromosomal instability (CIN) leading to aneuploidy is a ubiquitous and early event in the progression of Barrett's oesophagus, but its origins are unknown. Hence, the transcriptional levels of components of the mitotic spindle checkpoint (important in ensuring precise chromosome segregation) were examined in Barrett's... | ['Adenocarcinoma', 'Aneuploidy', 'Barrett Esophagus', 'Calcium-Binding Proteins', 'Cell Cycle Proteins', 'Cell Transformation, Neoplastic', 'Esophageal Neoplasms', 'Female', 'Gene Expression', 'Gene Expression Regulation, Neoplastic', 'HSP27 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Humans', 'Mad2 Proteins', 'Male'... | 15,013,707 | [['C04.557.470.200.025'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['C04.834.154', 'C06.405.117.102'], ['D12.776.157.125'], ['D12.776.167'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['G05.297'], ['G... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Affect processing in psychosomatic patients. I]. | The present article reports the results of an empirical investigation concerned with specific characteristics of psychosomatic patients. Subjects suffering from ulcus duodeni or from colitis ulcerosa designated as psychosomatic patients. Controls were chosen from among neurotic patients and from among patients with onl... | ['Adaptation, Psychological', 'Affect', 'Aggression', 'Anxiety', 'Colitis, Ulcerative', 'Defense Mechanisms', 'Duodenal Ulcer', 'Humans', 'Neurotic Disorders', 'Physician-Patient Relations', 'Psychological Tests', 'Psychophysiologic Disorders'] | 6,485,587 | [['F01.058'], ['F01.470.047'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.470.132'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['F01.393'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.550', 'F03... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mechanisms non-enzymatic browning in orange juice during storage. | The role of Reactive Carbonyl Species (RCS) derived from the Maillard reaction and ascorbic acid degradation on brown color formation was investigated in orange juice during storage. Eight RCS were monitored in aseptic juice over an 8-week period under refrigerated (4 °C) and accelerated conditions (35 °C). Significant... | ['Amino Acids', 'Chromatography, High Pressure Liquid', 'Citrus sinensis', 'Color', 'Deoxyglucose', 'Food Storage', 'Fructose', 'Fruit and Vegetable Juices', 'Glyoxal', 'Maillard Reaction', 'Mass Spectrometry', 'Spectrophotometry, Ultraviolet', 'Temperature'] | 30,955,619 | [['D12.125'], ['E05.196.181.400.300'], ['B01.650.940.800.575.912.250.875.177.769'], ['G01.590.540.199'], ['D09.254.229'], ['J01.576.423.200.387'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['G07.203.100.606', 'J02.200.606'], ['D02.047.644'], ['G02.607.522'], ['E05.196.566'], ['E05.196.712.726.802', 'E05.196.867.8... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Temporal-frequency tuning of cross-orientation suppression in the cat striate cortex. | A sinusoidal mask grating oriented orthogonally to and superimposed onto an optimally oriented base grating reduces a cortical neuron's response amplitude. The spatial selectivity of cross-orientation suppression (XOR) has been described, so for this paper we investigated the temporal properties of XOR. We recorded fro... | ['Animals', 'Cats', 'Feedback', 'Neural Inhibition', 'Neurons', 'Orientation', 'Visual Cortex', 'Visual Perception'] | 12,020,085 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['L01.906.394.211'], ['G07.265.755', 'G11.561.616'], ['A08.675', 'A11.671'], ['F01.058.577', 'F02.830.606'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953'], ['F02.463.593.932']] | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Isolation and partial characterization of an anti-bothropic complex from the serum of South American Didelphidae. | An anti-bothropic fraction (ABF) with anti-Bothrops jararaca venom activity tested in mice was isolated from the serum of some South American Didelphidae (Didelphis marsupialis, Philander opossum and Lutreolina crassicaudata) by DEAE-Sephacel chromatography. ABF from D. marsupialis was shown to be 12 times more active ... | ['Amino Acid Sequence', 'Animals', 'Antivenins', 'Blotting, Western', 'Bothrops', 'Chromatography, High Pressure Liquid', 'Chromatography, Ion Exchange', 'Crotalid Venoms', 'Electrophoresis, Polyacrylamide Gel', 'Lethal Dose 50', 'Mice', 'Molecular Sequence Data', 'Molecular Weight', 'Opossums', 'Sequence Homology, Ami... | 7,846,694 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.573.601.138', 'D12.776.124.790.651.114.573.601.138', 'D12.776.377.715.548.114.573.601.138', 'D20.215.401.601.163'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B01.050.150.900.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Meningeal rhabdomyosarcoma. Report of a case with cytologic, immunohistologic and ultrastructural studies. | Primary rhabdomyosarcoma of the meninges, a very rare brain tumor, is reported. Cytologic findings by squash preparation were useful as an adjunct to frozen section diagnosis during surgery. The cytologic features of rhabdomyosarcoma without cross-striation have some similarities to those of gemistocytic astrocytomas a... | ['Adult', 'Cytoskeleton', 'Factor VIII', 'Humans', 'Immunohistochemistry', 'Male', 'Meningeal Neoplasms', 'Microscopy, Electron', 'Myoglobin', 'Rhabdomyosarcoma', 'Vimentin'] | 7,762,328 | [['M01.060.116'], ['A11.284.430.214.190.750'], ['D12.776.124.125.350', 'D12.776.811.286', 'D23.119.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512',... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Spanish Pacemaker Registry. Twelfth Official Report of the Spanish Society of Cardiology Working Group on Cardiac Pacing (2014). | INTRODUCTION AND OBJECTIVES: This report describes the results of the analysis of pacemaker implant and replacement data submitted to the Spanish Pacemaker Registry in 2014, with special reference to pacing mode selection.METHODS: The report is based on the processing of information provided by the European Pacemaker P... | ['Age Distribution', 'Aged', 'Aged, 80 and over', 'Arrhythmias, Cardiac', 'Cardiac Pacing, Artificial', 'Cardiac Resynchronization Therapy', 'Cardiac Resynchronization Therapy Devices', 'Cardiology', 'Female', 'Health Smart Cards', 'Humans', 'Male', 'Middle Aged', 'Pacemaker, Artificial', 'Registries', 'Sex Distributio... | 26,553,269 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067', 'C23.550.073'], ['E02.331.200'], ['E02.331.200.500'], ['E07.305.250.750.500'], ['H02.403.429.163'], ['E05.318.308.940.968.625.750', 'L01.313.500.750.300.695.300', 'N04.452.653.250', 'N04.452.859.564.650... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Genetic analysis of avian influenza virus from wild birds and mallards reared for shooting in Denmark. | Denmark forms a geographical bottleneck along the migration route of many water birds breeding from northeastern Canada to north Siberia that gather to winter in Europe and Africa. Potentially, the concentration of such large numbers of water birds enhances the risk of avian influenza virus (AIV) introduction to domest... | ['Animals', 'Animals, Wild', 'Birds', 'Denmark', 'Influenza A virus', 'Influenza in Birds', 'Phylogeny'] | 20,521,672 | [['B01.050'], ['B01.050.050.300'], ['B01.050.150.900.248'], ['Z01.542.816.124'], ['B04.820.480.968.405.400'], ['C01.925.782.620.300', 'C22.131.450'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Tumour budding is a reproducible index for risk stratification of patients with stage II colon cancer. | AIM: High-risk patients with Stage II colon cancer may benefit from adjuvant chemotherapy, but it is difficult to identify such a patient group. A robust and reproducible index would be helpful to select the subset of Stage II colon cancer patients at high risk. This study investigated the potential prognostic signific... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma', 'Cohort Studies', 'Colonic Neoplasms', 'Disease Progression', 'Disease-Free Survival', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Prognosis', 'Proportional Hazards Models',... | 24,118,729 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C23.550.291.6... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of transcription initiation by lac repressor. | Initiation of transcription of the lac operon by RNA polymerase (R) is inhibited by binding of lac repressor (L) to an operator site which overlaps the lac promoter (P). We have investigated repression of the lac UV5 promoter in vitro for a choice of the repressor--operator binding constant and ranges of thermodynamic ... | ['DNA, Superhelical', 'DNA-Directed RNA Polymerases', 'Heparin', 'Kinetics', 'Lac Operon', 'Potassium Permanganate', 'Promoter Regions, Genetic', 'Repressor Proteins', 'Thermodynamics', 'Transcription, Genetic'] | 7,837,267 | [['D13.444.308.283.250', 'G02.111.570.820.486.212.250', 'G05.360.580.156.250'], ['D08.811.913.696.445.735.270'], ['D09.698.373.400'], ['G01.374.661', 'G02.111.490'], ['G05.360.340.024.686.545', 'G05.360.340.358.207.500.545'], ['D01.530.700', 'D01.745.750'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.34... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The gene transfection efficiency of a folate-PEI600-cyclodextrin nanopolymer. | The success of gene therapy relies on a safe and effective gene delivery system. In this communication, we describe the use of folate grafted PEI(600)-CyD (H(1)) as an effective polyplex-forming plasmid delivery agent with low toxicity. The structures of the polymer and polyplex were characterized, and the in vitro tra... | ['Animals', 'Cattle', 'Cyclodextrins', 'DNA', 'Drug Carriers', 'Female', 'Folic Acid', 'Imines', 'Melanoma', 'Mice', 'Mice, Inbred BALB C', 'Nanostructures', 'Polyethylenes', 'Polymers', 'Transfection'] | 19,615,741 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D04.345.103', 'D09.301.915.400.375', 'D09.698.365.855.400.375'], ['D13.444.308'], ['D26.255.260', 'E02.319.300.380'], ['D03.633.100.733.631.400'], ['D02.491'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['B01.050.150.900.649.313.99... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Hippocampal epigenetic modification at the doublecortin gene is involved in the impairment of neurogenesis with aging. | Recent research has suggested that epigenetic mechanisms, which exert lasting control over gene expression without altering the genetic code, could mediate stable changes in brain function. A growing body of evidence supports the idea that epigenetic changes play a role in the etiology of aging and its associated brain... | ['Aging', 'Animals', 'DNA Methylation', 'Dentate Gyrus', 'Epigenesis, Genetic', 'Gene Expression Regulation, Developmental', 'Genetic Markers', 'Hippocampus', 'Mice', 'Mice, Inbred C57BL', 'Microtubule-Associated Proteins', 'Neurogenesis', 'Neuropeptides', 'Promoter Regions, Genetic', 'Stem Cells'] | 20,340,168 | [['G07.345.124'], ['B01.050'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['A08.186.211.180.405.200', 'A08.186.211.200.885.287.500.345.200'], ['G05.308.203'], ['G05.308.310'], ['D23.101.387', 'G05.695.450'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developing a novel FRET assay, targeting the binding between Antizyme-AZIN. | Antizyme inhibitor (AZIN) stimulates cell proliferation by binding to and sequestering the cell cycle suppressor antizyme. Despite the important role of the antizyme-AZIN protein-protein interaction (PPI) in cell cycle regulation, there are no assays for directly measuring the binding of AZIN to antizyme that are amena... | ['Amino Acid Sequence', 'Animals', 'Biophysical Phenomena', 'Carrier Proteins', 'Fluorescence Resonance Energy Transfer', 'Humans', 'Ornithine Decarboxylase', 'Protein Binding', 'Proteins'] | 30,874,587 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G01.154'], ['D12.776.157'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.520.224.125.425'], ['G02.111.679', 'G03.808'], ['D12.776']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
No effect of extremely low-frequency magnetic field observed on cell growth or initial response of cell proliferation in human cancer cell lines. | An effect on the tumor promotion process, as represented by accelerated cell growth, has been indicated as one example of areas that demonstrate the possibility of biological effects of extremely-low frequency magnetic fields. We, therefore, exposed the five cell lines (HL-60, K-562, MCF-7, A-375, and H4) derived from ... | ['Cell Division', 'Culture Media', 'HL-60 Cells', 'Humans', 'K562 Cells', 'Magnetics', 'Tumor Cells, Cultured'] | 12,111,756 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D27.720.470.305', 'E07.206'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.510', 'A11.251.860.180.510', 'A11.443.240.497.480'], ['H01.671.493'], ['A11... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
United States emergency medicine block rotation curricula for the 1986-87 academic year. | Because emergency medicine is a broad-based specialty, there is much leeway in the structure of resident education. The monthly block curriculum is a major determinant of the overall residency training experience. The purpose of our study was to define the block curricula of the accredited emergency medicine residencie... | ['Curriculum', 'Emergency Medicine', 'Internship and Residency', 'United States'] | 3,177,993 | [['I02.158'], ['H02.403.250'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
Assessment of hypothalamic-pituitary function in patients with familial amyloidotic polyneuropathy. | This study was performed to evaluate hypothalamic-pituitary hormone regulation in patients with familial amyloidotic polyneuropathy. Twenty-two patients without clinically overt endocrinological dysfunction were studied. A thyrotropin-releasing hormone test revealed abnormal growth hormone regulation in 9 of 17 (53%) p... | ['Amyloidosis', 'Arginine Vasopressin', 'Female', 'Growth Hormone', 'Humans', 'Hypothalamo-Hypophyseal System', 'Insulin-Like Growth Factor I', 'Male', 'Middle Aged', 'Osmolar Concentration', 'Polyneuropathies', 'Prolactin', 'Thyrotropin-Releasing Hormone'] | 1,899,879 | [['C18.452.845.500'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Relationship between Attitudes toward Suicide and Family History of Suicide in Nagano Prefecture, Japan. | Certain attitudes toward suicide may be a risk factor for suicide among the bereaved. To explore this possibility, we examined the relationship between attitudes toward suicide and family history of suicide. We focused on two specific attitudes indicating resignation in a survey: #1 "When a person chooses to die by sui... | ['Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Death', 'Family', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Risk Factors', 'Suicide', 'Surveys and Questionnaires', 'Young Adult'] | 27,338,441 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.125', 'N05.300.125'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Reproductive hormones in relation to polycyclic aromatic hydrocarbon (PAH) metabolites among non-occupational exposure of males. | A limited number of studies have suggested that exposure to PAHs may affect reproductive hormones. Subjects (n=642) in this study were from the affiliated hospitals of Nanjing Medical University. Individual exposures to PAHs were measured as spot urinary concentrations of four PAH metabolites, including 1-naphthol (1-N... | ['Adult', 'China', 'Environmental Exposure', 'Environmental Monitoring', 'Estradiol', 'Fluorenes', 'Follicle Stimulating Hormone, Human', 'Hormones', 'Humans', 'Luteinizing Hormone', 'Male', 'Naphthols', 'Polycyclic Aromatic Hydrocarbons', 'Prolactin', 'Pyrenes', 'Reference Values', 'Testosterone'] | 19,942,255 | [['M01.060.116'], ['Z01.252.474.164'], ['N06.850.460.350'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D02.455.426.559.847.389', 'D04.615.389'], ['D06.472.699.631.525.343.288.625'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Experiment and computer-aided simulation: complementary tools to understand exercise metabolism. | During the last two decades the concept of the MLSS (maximal lactate steady state) has been established. The MLSS detects the highest level of the BLC (blood lactate concentration) and the corresponding workload (MLSS workload) that can be maintained over time without continual BLC accumulation. In spite of a lack of e... | ['Adult', 'Computer Simulation', 'Energy Metabolism', 'Exercise', 'Humans', 'Male'] | 14,641,039 | [['M01.060.116'], ['L01.224.160'], ['G03.295'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Vibrational spectra and surface-enhanced vibrational spectra of 1-nitropyrene. | The present report on the vibrational spectra of 1-nitropyrene (1NP) describes the infrared and Raman spectra; their interpretation is aided by local density functional theory (DFT) calculations at the B3LYP/6-311G(d, p) level of theory and by the surface-enhanced vibrational spectra (SEVS) with the final objective of ... | ['Air Pollutants', 'Algorithms', 'Microchemistry', 'Mutagens', 'Pyrenes', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectroscopy, Fourier Transform Infrared', 'Spectrum Analysis, Raman', 'Vibration'] | 15,165,332 | [['D27.888.284.101'], ['G17.035', 'L01.224.050'], ['E05.196.620', 'H01.181.650'], ['D27.888.569.468'], ['D02.455.426.559.847.799', 'D04.615.799'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Epifluorescent microscopy of earthworms' intestinal bacteria. | Epifluorescent microscopy was employed to compare the bacterial live counts (BC) in the gut of two earthworm species Aporrectodea caliginosa and Lumbricus rubellus, representing different ecophysiological groups. The average number of BC was 10.9 x 10(9) g-1 dry weight in the gut of A. caliginosa, 5.9 x 10(9) in that o... | ['Animals', 'Bacteria', 'Digestion', 'Feeding Behavior', 'Intestines', 'Microscopy, Fluorescence', 'Oligochaeta', 'Seasons', 'Soil Microbiology'] | 7,620,811 | [['B01.050'], ['B03'], ['G07.203.650.250', 'G10.261.190'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['A03.556.124'], ['E01.370.350.515.458', 'E05.595.458'], ['B01.050.500.091.657'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
A comparison of sesquiterpene scaffolds across different populations of the tropical marine sponge Acanthella cavernosa. | Specimens of the Indo-Pacific sponge Acanthella cavernosa Dendy collected from locations along the Eastern coastline of Australia have been shown to contain a range of sesquiterpenes including isothiocyanate 1, isocyanide 10, and the isocyanates 15 and 22. These metabolite studies have provided a basis for chemical com... | ['Animals', 'Australia', 'Marine Biology', 'Molecular Structure', 'Porifera', 'Sesquiterpenes'] | 17,953,446 | [['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['H01.158.273.248.750.500', 'H01.277.249.750.500', 'H01.277.750.500'], ['G02.111.570', 'G02.466'], ['B01.050.500.802'], ['D02.455.849.765']] | ['Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Evaluating family-centred service using a measure of parents' perceptions. | This article describes the use of a newly-developed measure of parents' perceptions of health care providers' behaviours (Measure of Processes of Care-MPOC) to evaluate the family centredness of children's rehabilitation services. The measure was developed with the participation of more than 1600 parents of children wi... | ['Adolescent', 'Analysis of Variance', 'Child', 'Child Health Services', 'Child, Preschool', 'Cleft Lip', 'Cleft Palate', 'Consumer Behavior', 'Developmental Disabilities', 'Female', 'Humans', 'Infant', 'Male', 'Ontario', 'Parents', 'Patient-Centered Care', 'Process Assessment, Health Care', 'Professional-Family Relati... | 9,023,031 | [['M01.060.057'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['M01.060.406'], ['N02.421.143.130'], ['M01.060.406.448'], ['C07.465.409.225', 'C07.465.525.164', 'C07.650.525.164', 'C16.131.850.525.164'], ['C05.500.460.185', 'C05.660.207.540.460.185', 'C07.320.440.185', 'C07.465.525.185', 'C07.650.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Validating the prediction of lower urinary tract infection in primary care: sensitivity and specificity of urinary dipsticks and clinical scores in women. | BACKGROUND: Dipsticks are one of the most commonly used near-patient tests in primary care, but few clinical or dipstick algorithms have been rigorously developed.AIM: To confirm whether previously documented clinical and dipstick variables and algorithms predict laboratory diagnosis of urinary tract infection (UTI).DE... | ['Adolescent', 'Adult', 'Aged', 'Clinical Laboratory Techniques', 'England', 'Female', 'Humans', 'Middle Aged', 'Predictive Value of Tests', 'Reagent Strips', 'Sensitivity and Specificity', 'Urinalysis', 'Urinary Tract Infections', 'Young Adult'] | 20,594,439 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225', 'E05.200'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['D27.505.259.875.680', 'D27.720.470.410.680.680', 'E07.720.720'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Rapid and accurate measurement of growth of solid tumours and changes in the tumour bed in the rat by the technique of volumetric displacement. | An apparatus which has been widely used in rats for measuring swelling of the foot induced locally by inflammatory agents has been adapted to measure rapidly, accurately and objectively, the growth of tumour cells transplanted to the foot, and the reactions of the normal tissues (tumour bed) to tumour growth. General ... | ['Animals', 'Biometry', 'Carcinoma 256, Walker', 'Female', 'Hindlimb', 'Inflammation', 'Neoplasm Transplantation', 'Neoplasms, Experimental', 'Rats'] | 831,762 | [['B01.050'], ['E05.318.740.225', 'N06.850.505.200'], ['C04.557.435.290.210', 'C04.557.450.795.290.210', 'C04.619.045'], ['A13.473'], ['C23.550.470'], ['E05.624'], ['C04.619', 'E05.598.500.496'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Phase I trial of continuous infusion carboplatin and etoposide in children with refractory acute leukemia: a Pediatric Oncology Group study. | PURPOSE: The purpose of this phase I study was to determine the toxicities and response to continuous infusion carboplatin in combination with a fixed dose of etoposide (VP-16) in children with refractory acute leukemia.PATIENTS AND METHODS: From January 1989 to February 1992, 20 patients received 28 courses of treatme... | ['Acute Disease', 'Adolescent', 'Antineoplastic Combined Chemotherapy Protocols', 'Bone Marrow', 'Carboplatin', 'Child', 'Child, Preschool', 'Diarrhea', 'Drug Administration Schedule', 'Etoposide', 'Female', 'Humans', 'Infections', 'Infusions, Intravenous', 'Leukemia', 'Male', 'Remission Induction', 'United States'] | 8,083,718 | [['C23.550.291.125'], ['M01.060.057'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['A15.382.216'], ['D02.257.125'], ['M01.060.406'], ['M01.060.406.448'], ['C23.888.821.214'], ['E02.319.283'], ['D02.455.426.559.847.638.960.675.250', 'D04.615.638.960.675.250', 'D09.408.348.275'], ['B01.050.150.900.649.313... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Respiratory responses of the domestic fowl to low level carbon dioxide exposure. | Respiratory function in the restrained, conscious domestic fowl was measured using a non-invasive technique and computer aided analysis to examine respiratory flow, and in-dwelling arterial catheters to monitor blood carbon dioxide levels. The effects of two low ranges of inspiratory carbon dioxide (0.2 to 1.0 per cent... | ['Analysis of Variance', 'Animals', 'Carbon Dioxide', 'Chickens', 'Female', 'Partial Pressure', 'Plethysmography', 'Respiration', 'Respiratory Function Tests'] | 3,085,182 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G01.374.715.714'], ['E01.370.370.610'], ['G09.772.705'], ['E01.370.386.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Species composition and seasonal dynamics of aphid parasitoids and hyperparasitoids in wheat fields in northern China. | Parasitoids are important natural enemies of aphids in wheat fields of northern China, and interest in them has increased in recent years. However, little is known regarding parasitoids of wheat aphids, which has hindered the study and understanding of aphid-parasitoid interactions. In the present study, three primary ... | ['Animals', 'Aphids', 'Biodiversity', 'China', 'Host-Parasite Interactions', 'Population Dynamics', 'Seasons', 'Species Specificity', 'Triticum'] | 29,070,808 | [['B01.050'], ['B01.050.500.131.617.412.165'], ['G16.500.275.157.049', 'N06.230.124.049'], ['Z01.252.474.164'], ['G16.527.200.400'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G16.824'], ['B01.650.940.800.575.912.250.822.918']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
The use of videotape in the treatment planning seminar. | Despite the drawbacks, the student evaluation of the seminar approach was positive. This reinforced the faculty's view that the seminar is a unique, interactive learning experience. The seminar provides a forum for faculty and students to integrate the various treatment planning and case management skills taught in ora... | ['Curriculum', 'Education, Dental', 'Humans', 'Interpersonal Relations', 'Interviews as Topic', 'Patient Care Planning', 'Students, Dental', 'Teaching', 'Videotape Recording'] | 3,456,369 | [['I02.158'], ['I02.358.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['N04.590.233.624'], ['M01.848.769.519'], ['I02.903'], ['J01.897.280.500.846.734', 'J01.897.280.500.898.840', 'L01.178.590.875.840', 'L01... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
Health promotion and injury prevention in a child development center. | The purpose of the study was to determine if a nurse-directed health promotion program in a day care center increased the health of the children in the center and decreased injury rates. The research used a quasi-experimental time series design to answer the research questions. The convenience sample consisted of 29 ch... | ['Analysis of Variance', 'Child Day Care Centers', 'Child, Preschool', 'Community Health Nursing', 'Health Promotion', 'Humans', 'Infant', 'Program Evaluation', 'Wounds and Injuries'] | 9,198,338 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['J03.160', 'N02.421.143.098'], ['M01.060.406.448'], ['H02.478.676.150', 'N02.421.143.150'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 |
[The influence of music on pictorial expression of young women--a comparative study of different music styles]. | Questing one's personal identity and developing a coherent representation of oneself, the other and the world are major tasks in adolescence. Research showed that a satisfactory resolution of the crisis of adolescence can be favoured by psychological counselling based on artistic mediations. The objective of this study... | ['Adolescent', 'Adult', 'Art', 'Female', 'Humans', 'Music', 'Paintings', 'Personality', 'Social Identification', 'Young Adult'] | 20,653,187 | [['M01.060.057'], ['M01.060.116'], ['K01.093'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.602'], ['K01.093.646'], ['F01.752'], ['F01.145.813.708'], ['M01.060.116.815']] | ['Named Groups [M]', 'Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Determination of fentanyl in human plasma by head-space solid-phase microextraction and gas chromatography-mass spectrometry. | A head-space solid-phase microextraction (HS-SPME) method coupled to GC-MS was developed to extract fentanyl from human plasma. The protein binding was reduced by acidification and, eventually, the sample was deproteinized with trichloroacetic acid. The parameters influencing adsorption (extraction time, temperature, p... | ['Analgesics, Opioid', 'Fentanyl', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Hydrogen-Ion Concentration', 'Molecular Structure', 'Reproducibility of Results', 'Salts', 'Sensitivity and Specificity', 'Solid Phase Microextraction', 'Temperature'] | 17,250,988 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D03.383.621.265'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G02.111.570', 'G02.466'], ['E05.318.370.725', 'E05.337.851', 'N0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
'Of Mice and Dementia': A filmed conversation on the use of animals in dementia research. | Preclinical science research focuses on the study of physiological systems regulating body functions, and how they are dysregulated in disease, in a non-human setting. For example, cells in a dish, computer simulations or animals. Scientific procedures traditionally involve a specialist scientist developing a hypothesi... | ['Animals', 'Communication', 'Community Participation', 'Dementia', 'Disease Models, Animal', 'Ethics, Research', 'Humans', 'Mice', 'Motion Pictures', 'Research'] | 30,373,455 | [['B01.050'], ['F01.145.209', 'L01.143'], ['N02.421.143.212', 'N03.540.245.360'], ['C10.228.140.380', 'F03.615.400'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['K01.752.566.479.173', 'N05.350.670'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['J01.897.280.500.598... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Mechanism of endothelial cell shape change and cytoskeletal remodeling in response to fluid shear stress. | Endothelium exposed to fluid shear stress (FSS) undergoes cell shape change, alignment and microfilament network remodeling in the direction of flow by an unknown mechanism. In this study we explore the role of tyrosine kinase (TK) activity, intracellular calcium ([Ca2+]i), mechanosensitive channels and cytoskeleton in... | ['Acrylamide', 'Acrylamides', 'Actin Cytoskeleton', 'Actins', 'Alkaloids', 'Animals', 'Barium Compounds', 'Benzophenanthridines', 'Calcium', 'Cattle', 'Cell Size', 'Cells, Cultured', 'Chlorides', 'Cytoskeleton', 'Endothelium, Vascular', 'Gadolinium', 'Hemorheology', 'Microtubules', 'Phalloidine', 'Phenanthridines', 'Po... | 8,718,663 | [['D02.065.122.015', 'D02.241.081.069.094.015'], ['D02.065.122', 'D02.241.081.069.094'], ['A11.284.430.214.190.750.050'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D03.132'], ['B01.050'], ['D01.103'], ['D03.132.089', 'D03.633.300.633.207', 'D03.633.400.131'], ['D01.268.552.100', 'D01.552.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Bioinformatic analysis of dengue virus cDNAs and design of oligonucleotide probes for microarray detection of the virus]. | OBJECTIVE: To design oligonucleotide probes for microarray detection of dengue virus.METHODS: By analyzing the cDNAs of dengue viruses of 4 different serotypes with BLAST program, a group of specific sequences for the candidate probes was acquired. Oligo6.0 software was applied to analyze the candidates to select the p... | ['Base Sequence', 'Computational Biology', 'Dengue Virus', 'Molecular Sequence Data', 'Oligonucleotide Array Sequence Analysis', 'Oligonucleotide Probes'] | 13,129,715 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['H01.158.273.180', 'L01.313.124'], ['B04.820.578.344.350.270'], ['L01.453.245.667'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['D13.444.600.601', 'D27.505.259.750.600.650', 'D27.720.470.530.600.650']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Control of lambda repressor prophage and establishment transcription by the product of gene tof. | Control of expression of the bacteriophage lambda (lambda) repressor was studied by measuring repressor transcription in noninduced and derepressed lambda lysogens. Three distinct modes of leftward transcription were observed from cI and the adjacent genes associated with the control of repressor synthesis: The propha... | ['Coliphages', 'DNA Replication', 'DNA, Viral', 'Enzyme Repression', 'Genes, Regulator', 'Genes, Viral', 'Lysogeny', 'RNA, Messenger', 'RNA, Viral', 'Transcription, Genetic'] | 703,760 | [['B04.123.205'], ['G02.111.225', 'G05.226'], ['D13.444.308.568'], ['G05.308.320.300'], ['G05.360.340.024.340.425'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['G05.935.500', 'G06.920.877.500'], ['D13.444.735.544'], ['D13.444.735.828'], ['G02.111.873', 'G05.297.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of UPR pathway in defense response of Aedes aegypti against Cry11Aa toxin from Bacillus thuringiensis. | The insecticidal Cry toxins are pore-forming toxins produced by the bacteria Bacillus thuringiensis that disrupt insect-midgut cells. Cells can trigger different survival mechanisms to counteract the effects of sub-lytic doses of pore forming toxins. Particularly, two signaling pathways have been demonstrated to play a... | ['Aedes', 'Animals', 'Bacillus thuringiensis', 'Bacillus thuringiensis Toxins', 'Bacterial Proteins', 'DNA-Binding Proteins', 'Endotoxins', 'Genes, Insect', 'Hemolysin Proteins', 'Insect Proteins', 'Larva', 'Phylogeny', 'RNA Interference', 'Regulatory Factor X Transcription Factors', 'Signal Transduction', 'Sterol Regu... | 23,594,997 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['D23.946.123.090'], ['D12.776.097'], ['D12.776.260'], ['D23.946.123.329'], ['G05.360.340.024.340.34... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Adenomyomatosis of the gallbladder--case report. | Adenomyomatosis of the gallbladder is a benign, mostly asymptomatic condition of an unknown aetiology. Hyperplastic changes in the gallbladder wall cause an overgrowth of the mucosa, thickening of the muscular wall, and formation of intramural diverticula or sinus tracts termed Rokitansky-Aschoff sinuses. Adenomyomatos... | ['Adenomyoma', 'Adult', 'Asymptomatic Diseases', 'Female', 'Gallbladder Neoplasms', 'Humans'] | 21,789,927 | [['C04.557.435.110'], ['M01.060.116'], ['C23.550.291.187'], ['C04.588.274.120.401', 'C06.130.320.401', 'C06.130.564.401', 'C06.301.120.401'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The first total synthesis of the cyclodepsipeptide pipecolidepsin A. | Pipecolidepsin A is a head-to-side-chain cyclodepsipeptide isolated from the marine sponge Homophymia lamellosa. This compound shows relevant cytotoxic activity in three human tumour cell lines and has unique structural features, with an abundance of non-proteinogenic residues, including several intriguing amino acids.... | ['Animals', 'Cell Line, Tumor', 'Depsipeptides', 'Female', 'HT29 Cells', 'Hep G2 Cells', 'Humans', 'MCF-7 Cells', 'Male', 'Neoplasms', 'Pipecolic Acids', 'Porifera', 'Structure-Activity Relationship'] | 23,989,475 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['D04.345.566.297', 'D12.644.641.297'], ['A11.251.210.190.475', 'A11.251.860.180.475', 'A11.436.365'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.630'], ['C04'], ['D03.066.758', 'D03.383.621.758'], ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mouse eosinophils possess potent antibacterial properties in vivo. | Eosinophils are best known as the predominant cellular infiltrate associated with asthma and parasitic infections. Recently, numerous studies have documented the presence of Toll-like receptors (TLRs) on the surfaces of eosinophils, suggesting that these leukocytes may participate in the recognition and killing of viru... | ['Animals', 'Anti-Bacterial Agents', 'Eosinophil Cationic Protein', 'Eosinophils', 'Female', 'Interleukin-5', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Pseudomonas Infections'] | 19,703,974 | [['B01.050'], ['D27.505.954.122.085'], ['D08.811.277.352.700.350.262', 'D12.776.124.486.379.249'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['D12.644.276.374.465.202', 'D12.776.467.374.465.186', 'D23.529.374.465.202'], ['B01.050.150.900.649.313.992.635.505.500'], ['B... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical treatment of chronic pancreatitis, complicated by intracystic bleeding]. | Data of 14 patients with chronic cystic pancreatitis, complicated by intracystic bleeding, were analyzed. Early diagnosis of a bleeding episode provides an in-time diagnostic and treatment procedures. Angiographic bleeding vessel occlusion is considered to be a method of choice. When the latter is impossible, a method ... | ['Adult', 'Female', 'Hemostasis, Surgical', 'Humans', 'Male', 'Middle Aged', 'Pancreatic Cyst', 'Pancreatitis, Chronic', 'Postoperative Hemorrhage', 'Radiography', 'Ultrasonography'] | 20,559,207 | [['M01.060.116'], ['E02.520.490', 'E04.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.182.640', 'C06.689.500'], ['C06.689.750.830'], ['C23.550.414.941', 'C23.550.767.850'], ['E01.370.350.700'], ['E01.370.350.850']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The treatment of stroke in internal medicine wards or in an intensive care unit?]. | The mortality and complication rates have been studied in a series of 92 patients with stroke, who have been treated in a general medicine ward in central Italy. The data have been compared and discussed in relationship with analogous parameters reported about some series from north-European stroke units (SU) and gener... | ['Aged', 'Aged, 80 and over', 'Cerebrovascular Disorders', 'Female', 'Humans', 'Intensive Care Units', 'Internal Medicine', 'Italy', 'Length of Stay', 'Male', 'Middle Aged', "Patients' Rooms", 'Prognosis', 'Retrospective Studies'] | 10,228,353 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300', 'C14.907.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['H02.403.429'], ['Z01.542.489'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['N02.278.220.640'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.3... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Application of a Framework to Implement Trauma-Informed Care Throughout a Pediatric Health Care Network. | INTRODUCTION: To evaluate the initial application of a recently published three-step framework for implementing trauma-informed care (TIC) in a pediatric health care network by applying Framework for Spread.METHODS: In steps 1 and 2 of the framework, we established commitment from the health care network leadership and... | ['Adult', 'Attitude of Health Personnel', 'Child', 'Child Health Services', 'Education, Continuing', 'Female', 'Health Personnel', 'Humans', 'Male', 'Middle Aged', 'Quality Improvement', 'Self Efficacy', 'Surveys and Questionnaires', 'Teaching', 'Trauma Centers'] | 28,252,468 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['M01.060.406'], ['N02.421.143.130'], ['I02.358.212'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['J01.293.754', 'N04.761.744'], ['F01.752.747.792.700'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Spontaneous Emergence of Legibility in Writing Systems: The Case of Orientation Anisotropy. | Cultural forms are constrained by cognitive biases, and writing is thought to have evolved to fit basic visual preferences, but little is known about the history and mechanisms of that evolution. Cognitive constraints have been documented for the topology of script features, but not for their orientation. Orientation a... | ['Anisotropy', 'Humans', 'Visual Perception', 'Writing'] | 29,023,934 | [['G01.590.040', 'G02.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932'], ['L01.559.423.906']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Differential polycythemia: a comparative study between spurious polycythemia and pure erythrocytosis. | The definite differential diagnosis between spurious polycythemia (SP) and pure erythrocytosis (PE) was tested. Serum erythropoietin (EPO) levels in 6 patients with PE were 12.8 +/- 3.7 mU/ml and were significantly lower than those of both 19 normal controls (28.5 +/- 15.0 mU/ml) and 9 patients with SP (21.3 +/- 10.2 m... | ['Adult', 'Aged', 'Bone Marrow Cells', 'Diagnosis, Differential', 'Erythrocyte Indices', 'Erythropoietin', 'Female', 'Hematopoietic Stem Cells', 'Humans', 'Male', 'Middle Aged', 'Polycythemia', 'Polycythemia Vera'] | 3,686,523 | [['M01.060.116'], ['M01.060.116.100'], ['A11.148', 'A15.378.316'], ['E01.171'], ['E01.370.225.625.230', 'E05.200.625.230', 'G09.188.260'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.90... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Controlled dual drug release by coaxial electrospun fibers - Impact of the core fluid on drug encapsulation and release. | Controlled release of hydrophilic drugs from carriers is still faced with problems due to the poor compatibility of such substances with slowly degradable polymers leading to challenges regarding fabrication as well as undesired burst release of the encapsulated drugs. In this context, coaxial electrospinning being cap... | ['Acyclovir', 'Chemistry, Pharmaceutical', 'Delayed-Action Preparations', 'Drug Carriers', 'Drug Combinations', 'Drug Liberation', 'Hydrophobic and Hydrophilic Interactions', 'Kinetics', 'Polymers', 'Serum Albumin, Bovine', 'Solvents', 'Technology, Pharmaceutical'] | 30,572,080 | [['D03.633.100.759.758.399.454.250'], ['H01.158.703.007', 'H01.181.466'], ['D26.255.210', 'E02.319.300.253'], ['D26.255.260', 'E02.319.300.380'], ['D26.310'], ['G02.211', 'G03.787.321', 'G07.690.725.321'], ['G02.409'], ['G01.374.661', 'G02.111.490'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D12.776.034.841.540', 'D... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Functional role of prostacyclin receptor in rat dorsal root ganglion neurons. | Recent studies on prostanoids showed that some of prostanoid receptors are expressed in rat dorsal root ganglion (DRG) neurons. These facts suggest that prostanoid receptors might be involved in the excitation mechanism of DRG neurons. In the present study, PCR experiments revealed that one of prostanoid receptor, pros... | ['Animals', 'Animals, Newborn', 'Capsaicin', 'Cells, Cultured', 'Cyclic AMP', 'Cystitis, Interstitial', 'Disease Models, Animal', 'Female', 'Ganglia, Spinal', 'Iloprost', 'Inflammation Mediators', 'Membrane Potentials', 'Neurons, Afferent', 'Nociceptors', 'Pain', 'Potassium Chloride', 'Prostaglandins', 'Rats', 'Rats, S... | 16,039,053 | [['B01.050'], ['B01.050.050.282'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10.251.355.325.190'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['C12.777.829.495.500', 'C13.351.968.829.495.500'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new method for the diagnosis of Trichomonas gallinae infection by culture. | Diagnosis of Trichomonas gallinae infection can reliably be made by the demonstration of organisms in material taken from a bird's mouth and crop. This can be examined directly or incubated in a growth medium until organisms are numerous enough to be easily found in aliquots examined with the microscope. We compared tw... | ['Animals', 'Bird Diseases', 'Columbidae', 'Crop, Avian', 'Culture Media', 'Mouth', 'Reagent Kits, Diagnostic', 'Sensitivity and Specificity', 'Trichomonas', 'Trichomonas Infections'] | 7,933,297 | [['B01.050'], ['C22.131'], ['B01.050.150.900.248.165.150'], ['A13.265'], ['D27.720.470.305', 'E07.206'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Radiofrequency Ablation Pulmonary Metastasis of Colorectal Cancer - Two Cases of Report]. | Case 1: 63-year-old woman received abdominoperineal resection with lateral lymph node dissection for rectal cancer in 2008. After adjuvant chemotherapy, she suffered from lung metastasis and received partial pneumonectomy in 2012. However, chemotherapy was performed again for lung metastasis and mediastinal lymph nodes... | ['Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Catheter Ablation', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Rectal Neoplasms'] | 29,394,799 | [['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.808.750.500', 'E04.014.760.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.24... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neuroprotection by mefenamic acid against D-serine: involvement of oxidative stress, inflammation and apoptosis. | Mefenamic acid, a non-steroidal antiinflammatory drug (NSAID), directly and dose-dependently exhibits neuroprotective activity. In our study, we investigated the effects of mefenamic acid against d-serine on oxidative stress in the hippocampus, cortex and cerebellum of rats. Furthermore, the potential inflammatory and ... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Apoptosis', 'Brain', 'Inflammation', 'Mefenamic Acid', 'Neurodegenerative Diseases', 'Neuroprotective Agents', 'Oxidative Stress', 'Rats', 'Rats, Sprague-Dawley', 'Serine'] | 22,369,458 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G04.146.954.035'], ['A08.186.211'], ['C23.550.470'], ['D02.241.223.100.050.400.200.555', 'D02.455.426.559.389.127.020.906.750.555'], ['C10.574'], ['D27.505.696.706.548', 'D27.505.954.427.575'], ['G03.673', 'G07.775.750'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii. | Members of the immunity-related GTPase (IRG) family are interferon-inducible resistance factors against a broad spectrum of intracellular pathogens including Toxoplasma gondii. The molecular mechanisms governing the function and regulation of the IRG resistance system are largely unknown. We find that IRG proteins func... | ['Animals', 'Cell Line', 'Fibroblasts', 'GTP-Binding Proteins', 'Immunity, Innate', 'Interferons', 'Mice', 'Toxoplasma', 'Two-Hybrid System Techniques'] | 18,772,884 | [['B01.050'], ['A11.251.210'], ['A11.329.228'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['G12.450.564'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.043.075.189.250.750.800'], ['E05.393.220.870', 'E05.601.690.650', 'E05.601.870']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a single-cassette system for spatiotemporal gene regulation in mice. | The tetracycline-regulated gene expression system has been widely used in mice to turn a transgene on and off in a target organ, but with only limited success. We developed an advanced system in which a Tet-off regulation unit was integrated into the ROSA26 locus and became active after Cre-mediated excision of the neo... | ['Animals', 'Gene Expression Regulation', 'Gene Silencing', 'Genetic Engineering', 'Homeodomain Proteins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Recombinant Proteins', 'Tetracycline', 'Tissue Distribution', 'Trans-Activators', 'Transcriptional Activation'] | 16,256,950 | [['B01.050'], ['G05.308'], ['G05.308.203.374'], ['E05.393.420'], ['D12.776.260.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['D12.776.828'], ['D02.455.426.55... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genome-wide analysis, evolutionary expansion, and expression of early auxin-responsive SAUR gene family in rice (Oryza sativa). | Small auxin-up RNAs (SAURs) are the early auxin-responsive genes represented by a large multigene family in plants. Here, we report the identification of 58 OsSAUR gene family members from rice (Oryza sativa japonica cv Nipponbare), the model monocot plant, by a reiterative database search and manual reannotation; 2 of... | ['Base Sequence', 'Evolution, Molecular', 'Expressed Sequence Tags', 'Gene Duplication', 'Gene Expression Regulation, Plant', 'Genome, Plant', 'Indoleacetic Acids', 'Molecular Sequence Data', 'Oryza', 'Phylogeny', 'Plant Proteins'] | 16,707,243 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.137.275'], ['G05.365.590.320', 'G05.558.320'], ['G05.308.375'], ['G05.360.340.365'], ['D03.066.288', 'D03.633.100.473.404'], ['L01.453.245.667'], ['B01.650.940.800.575.912.250.822.616'], ['G05.697', 'G16.07... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phenotypic polymorphism of haptoglobin: a novel risk factor for the development of infection in liver cirrhosis. | The á-chain alleles 1 and 2 of haptoglobin (Hp) molecule account for three phenotypes, which have biologically important differences in their antioxidant, scavenging, and immunomodulatory properties and may thereby influence the course of inflammatory diseases. A follow-up observational study was conducted to assess th... | ['Aged', 'Alleles', 'Bacterial Infections', 'Cohort Studies', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Haptoglobins', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Phenotype', 'Polymorphism, Genetic', 'Risk Factors', 'Survival Analysis'] | 21,262,313 | [['M01.060.116.100'], ['G05.360.340.024.340.030'], ['C01.150.252'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.373'], ['B01.050.150.900.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Surgical anatomy of the cribriform plate and adjacent areas. | Continuous improvement of surgical techniques is needed in skull base surgery in order to decrease intraoperative complications during various operations. However, the basis of minimizing damage in the operative field is a comprehensive knowledge of microsurgical anatomy. This article provides a detailed description of... | ['Adult', 'Aged', 'Body Weights and Measures', 'Cephalometry', 'Child', 'Child, Preschool', 'Cranial Fossa, Anterior', 'Ethmoid Bone', 'Ethmoid Sinus', 'Fetus', 'Frontal Lobe', 'Humans', 'Infant, Newborn', 'Olfactory Bulb', 'Orbit', 'Radiography'] | 15,747,213 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['M01.060.406.448'], ['A01.456.830.150', 'A02.835.232.781.750.150'], ['A02.835.232.781.292'], ['A04.531.621.267'], ['A16.378'], ['A08.186.211.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Economic values for production and functional traits and assessment of their influence on genetic improvement in the Boran cattle in Kenya. | Economic values for production (sale weight in steers, SWs, kg and heifers, SWh, kg; dressing percentage, DP; consumable meat percentage, CMP and milk yield, MY, kg) and functional (cow weight, CoWT, kg; cow survival rate, CoSR, %; postweaning survival rate, PSR, %; feed intake of cows, FIc, heifers, FIh and steers, FI... | ['Animal Husbandry', 'Animals', 'Breeding', 'Cattle', 'Kenya', 'Phenotype', 'Selection, Genetic'] | 16,420,262 | [['J01.040.090'], ['B01.050'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.500.380.271'], ['Z01.058.290.120.400'], ['G05.695'], ['G05.783']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Are patients open to elective re-sampling of their glioblastoma? A new way of assessing treatment innovations. | BACKGROUND: This is a qualitative study designed to examine patient acceptability of re-sampling surgery for glioblastoma multiforme (GBM) electively post-therapy or at asymptomatic relapse.METHODS: Thirty patients were selected using the convenience sampling method and interviewed. Patients were presented with hypothe... | ['Adult', 'Aged', 'Brain Neoplasms', 'Elective Surgical Procedures', 'Female', 'Glioblastoma', 'Humans', 'Male', 'Middle Aged', 'Neurosurgical Procedures', 'Patient Acceptance of Health Care', 'Qualitative Research', 'Reoperation', 'Young Adult'] | 25,085,543 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E04.249'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.525'], ['F01.100.150.750.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Bifidobacterium pseudolongum in the Ceca of Rats Fed Hi-Maize Starch Has Characteristics of a Keystone Species in Bifidobacterial Blooms. | Starches resistant to mammalian digestion are present in foods and pass to the large bowel, where they may be degraded and fermented by the microbiota. Increases in relative abundances of bifidobacteria (blooms) have been reported in rats whose diet was supplemented with Hi-Maize resistant starch. We determined that th... | ['Animal Feed', 'Animals', 'Bacterial Proteins', 'Bifidobacterium', 'Cecum', 'Gastrointestinal Microbiome', 'Glycoside Hydrolases', 'Rats', 'Starch', 'Zea mays', 'alpha-Amylases'] | 29,802,187 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['D12.776.097'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['D08.811.277.450'], ['B01.050.150.900.649.313.992.635.505.700... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The radical scavenging abilities of a new anti-nephritic drug, OPC-15161. | A new anti-nephritic drug, 6-(1H-indol-3-ylmethyl)-5-methoxy-3-(2-methylpropyl)-2-(1H)-pyr azi none 4-oxide (OPC-15161), a natural product derivative, did not react with the free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and was only slightly reactive with superoxide (O2-), but it easily reacted with hydroxyl radic... | ['Bepridil', 'Biphenyl Compounds', 'Electron Spin Resonance Spectroscopy', 'Free Radical Scavengers', 'Hydroxyl Radical', 'Picrates', 'Pyrazines', 'Superoxides'] | 8,850,518 | [['D03.383.773.107'], ['D02.455.426.559.389.185'], ['E05.196.867.519.274'], ['D27.505.519.217.500'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['D02.455.426.559.389.657.566.690', 'D02.640.743.690'], ['D03.383.679'], ['D01.248.497.158.685.750.850', 'D01.339.431.374.850', 'D01.650.550.750.800', '... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Resource utilisation and cost of amblyopia treatment]. | BACKGROUND: The cost-effectiveness of screening for amblyopia is a controversial issue of international debate. The purpose of this study was to estimate the cost of amblyopia treatment to be used as a component for modelling the cost-effectiveness of prevention programmes. Cost was calculated from the perspective of t... | ['Amblyopia', 'Costs and Cost Analysis', 'Fee Schedules', 'Germany', 'Health Care Costs', 'Health Resources', 'Humans', 'National Health Programs', 'Patient Care Team', 'Utilization Review'] | 12,886,509 | [['C10.228.140.055', 'C10.597.751.941.073', 'C11.966.073', 'C23.888.592.763.941.073'], ['N03.219.151'], ['N04.452.313'], ['Z01.542.315'], ['N03.219.151.400', 'N05.300.375'], ['N03.349.340', 'N05.300.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550'], ['N04.590.715'], ['N04.761.879', 'N05.700.900']] | ['Diseases [C]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials. | Microfluidic manufacturing platforms have advanced the production of monodisperse, shape-controlled, and chemically defined micromaterials. However, conventional microfabrication platforms are typically designed and fabricated as single-purpose and single-use tools, which limits their efficiency, versatility, and overa... | ['Equipment Design', 'Lab-On-A-Chip Devices', 'Microspheres', 'Oils', 'Water'] | 31,017,163 | [['E05.320'], ['E07.305.343.500'], ['E07.565'], ['D10.627'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Next Generation Sequencing identifies mutations in GNPTG gene as a cause of familial form of scleroderma-like disease. | BACKGROUND: Scleroderma is a multisystem disease, characterized by fibrosis of skin and internal organs, immune dysregulation, and vasculopathy. The etiology of the disease remains unknown, but it is likely multifactorial. However, the genetic basis for this condition is defined by multiple genes that have only modest ... | ['Adolescent', 'DNA Mutational Analysis', 'Diagnosis, Differential', 'Heterozygote', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Male', 'Morocco', 'Mucolipidoses', 'Mutation', 'Pedigree', 'Scleroderma, Systemic', 'Siblings', 'Transferases (Other Substituted Phosphate Groups)', 'Whole Exome Sequencing'] | 28,950,892 | [['M01.060.057'], ['E05.393.760.700.300'], ['E01.171'], ['G05.380.383'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.266.629'], ['C05.116.198.371', 'C10.228.140.163.100.435.590', 'C16.320.565.189.435.590', 'C16.320.565.202.670', 'C16.320.565.595.554.590', 'C18.452.132.100.435.590', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Fumaric Acids Directly Influence Gene Expression of Neuroprotective Factors in Rodent Microglia. | Dimethylfumarate (DMF) has been approved the for treatment of relapsing-remitting multiple sclerosis. The mode of action of DMF and its assumed active primary metabolite monomethylfumarate (MMF) is still not fully understood, notably for brain resident cells. Therefore we investigated potential direct effects of DMF an... | ['Animals', 'Cell Differentiation', 'Cell Proliferation', 'Dimethyl Fumarate', 'Fumarates', 'Gene Expression Regulation', 'Insulin-Like Growth Factor I', 'Maleates', 'Microglia', 'Neuroprotective Agents', 'Oligodendroglia', 'Phagocytosis', 'Rats, Sprague-Dawley', 'Stem Cells'] | 30,650,518 | [['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['D02.241.081.337.302.500'], ['D02.241.081.337.302'], ['G05.308'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['D02.241.081.337.502'], ['A08.637.400', 'A11.650.400'], ['D27.505.696.706.548', 'D27.505.954.42... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Guarana (Paullinia cupana Mart.) alters gut microbiota and modulates redox status, partially via caffeine in Wistar rats. | Microbiota alterations are observed in pathological conditions, and their regulation is a subject of great interest. Gut microbes are affected by diet, and plant polyphenols may have positive effect on gut microbiota; however, plant-derived extracts may have toxic effects. Guarana (Paullinia cupana Mart.) is a nontradi... | ['Animals', 'Antioxidants', 'Caffeine', 'Dysbiosis', 'Gastrointestinal Microbiome', 'Male', 'Oxidation-Reduction', 'Oxidative Stress', 'Paullinia', 'Plant Extracts', 'Plants, Medicinal', 'Rats', 'Rats, Wistar', 'Seeds', 'Theobromine', 'Theophylline'] | 30,277,282 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['C23.550.308'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['G02.700', 'G03.295.531'], ['G03.673', 'G07.775.750'], ['B01.650.940.800.575.912.250.885.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Multilocus sequence analysis for Mycoplasma synoviae molecular genotyping. | The aim of this study was to identify molecular techniques which enable clear discrimination between Mycoplasma synoviae isolates for improved epidemiology. Multilocus sequence analysis (MLSA) of 6 M. synoviae loci was conducted for genotyping of isolates with previously determined 5'-vlhA sequences. Sequencing of thre... | ['Animals', 'Bacterial Proteins', 'Chickens', 'Genotype', 'Molecular Sequence Data', 'Multilocus Sequence Typing', 'Mycoplasma Infections', 'Mycoplasma synoviae', 'Phylogeny', 'Poultry Diseases', 'Sequence Analysis, DNA'] | 26,513,666 | [['B01.050'], ['D12.776.097'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G05.380'], ['L01.453.245.667'], ['E01.370.225.875.150.125.457.500', 'E05.200.875.150.125.457.500', 'E05.393.542.500', 'E05.393.760.700.650'], ['C01.150.252.400.610.610'], ['B03.440.860.580.553.553.770'], ['G05.697', 'G16.07... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A high lymph node yield in colon cancer is associated with age, tumour stage, tumour sub-site and priority of surgery. Results from a prospective national cohort study. | AIM: To determine the relation between patient-related and histopathological factors, as well as the influence of national programs for diagnosing and treatment of colon cancer and a lymph node yield (LNY) ? 12.METHOD: An analysis was carried out of the LNY in a nationwide Danish cohort treated by curative resection of... | ['Age Factors', 'Aged', 'Colonic Neoplasms', 'Denmark', 'Female', 'Humans', 'Logistic Models', 'Lymph Nodes', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prospective Studies'] | 27,220,610 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['Z01.542.816.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.45... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation. | Cytochrome b(5) (b(5)) is increasingly recognized to be of importance for specific cytochrome P450 (CYP) activities. We developed human b(5)/CYP-competent mutagenicity tester bacteria to study the role of b(5) in the bioactivation activity of human CYP. These new tester bacteria were derived from the previously enginee... | ['Aryl Hydrocarbon Hydroxylases', 'Biotransformation', 'Carcinogens', 'Cytochrome P-450 CYP1A2', 'Cytochrome P-450 CYP2A6', 'Cytochrome P-450 CYP2E1', 'Cytochromes b5', 'Enzyme Activation', 'Escherichia coli K12', 'Humans', 'In Vitro Techniques', 'Mixed Function Oxygenases', 'Mutagenicity Tests', 'Mutagens', 'NADPH-Fer... | 15,728,263 | [['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D27.888.569.100'], ['D08.244.453.005.443', 'D08.244.453.100.750', 'D08.811.682.690.708.170.010.443', 'D08.811.682.690.708.170.020.750', 'D12.776.422.220.453.010.443', 'D12.776.422.220.453.100... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Free vascularized tissue transfer for limb salvage in peripheral vascular disease. | In patients with tissue necrosis, higher limb salvage rates can be accomplished with free tissue transfers performed by a vascular and plastic surgeon team. We treated 10 patients with severe ischemic soft tissue defects in their legs with radical debridement and free tissue transfer alone (two patients) or after revas... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angiography', 'Female', 'Follow-Up Studies', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Necrosis', 'Surgery, Plastic', 'Surgical Flaps', 'Vascular Diseases', 'Vascular Surgical Procedures'] | 2,340,246 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.700.060', 'E01.370.370.050'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['C23.550.717'], ['H02.403.810... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro screening of selected probiotic properties of Lactobacillus strains isolated from traditional fermented cabbage and cucumber. | Most important during probiotic selection are gastric acid and bile tolerance, the adhesion to the luminal epithelium to colonize the lower gastrointestinal tract of a human and safety for human consumption. The aim of this study was to evaluate the selected probiotic in vitro properties of Lactobacillus spp. Strains i... | ['Anti-Bacterial Agents', 'Bile Acids and Salts', 'Brassica', 'Cell Membrane', 'Cucumis sativus', 'Food Microbiology', 'Food, Preserved', 'Humans', 'Hydrogen-Ion Concentration', 'Hydrophobic and Hydrophilic Interactions', 'Lactobacillus', 'Microbial Sensitivity Tests', 'Microbial Viability', 'Phylogeny', 'Probiotics', ... | 25,270,682 | [['D27.505.954.122.085'], ['D04.210.500.105'], ['B01.650.940.800.575.912.250.157.200'], ['A11.284.149'], ['B01.650.940.800.575.912.250.300.188.666'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['G07.203.300.521', 'J02.500.521'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway. | Oral helminthic mebendazole (MBZ) has been reported to cause liver injury with inflammatory responses. However, the underlying mechanism remains unknown. To examine the inflammatory reactions, we investigated whether MBZ and other helminthic drugs increase the release of pro-inflammatory cytokines and chemokines using ... | ['Anthracenes', 'Antinematodal Agents', 'Cell Line, Tumor', 'Cells, Cultured', 'Chemokines', 'Cytokines', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'Extracellular Signal-Regulated MAP Kinases', 'Humans', 'Imidazoles', 'Interleukin-8', 'Mebendazole', 'Mitogen-Activated Protein Kinases', 'Monocytes', 'Pyri... | 20,848,085 | [['D02.455.426.559.847.117', 'D04.615.117'], ['D27.505.954.122.250.075.080'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.251'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.875', 'G07.690.936.500'... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Three-dimensional ultrasound-based image-guided hypofractionated radiotherapy for intermediate-risk prostate cancer: results of a consecutive case series. | External beam radiotherapy (EBRT) is a standard of care in the treatment of prostate cancer. Hypofractionation is a valid option either radiobiologically and logistically in this context. Image-guidance procedures are strongly needed to provide ballistic precision to radiation delivery. The Clarity platform allows for ... | ['Aged', 'Dose Fractionation, Radiation', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Middle Aged', 'Prostatic Neoplasms', 'Radiotherapy, Image-Guided', 'Treatment Outcome', 'Ultrasonography'] | 25,526,035 | [['M01.060.116.100'], ['E02.815.639.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['M01.060.116.630'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E02.815.768'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Multiparametric assessment of left atrial remodeling using 18 | BACKGROUND: Left atrial (LA) remodeling is associated with structural, electric, and metabolic LA changes. Integrated evaluation of these features in vivo is lacking.METHODS: Patients undergoing 18F-fluorodeoxyglucose (FDG) PET-CT during a hyperinsulinemic-euglycemic clamp were classified into sinus rhythm (SR), paroxy... | ['Aged', 'Aged, 80 and over', 'Atrial Fibrillation', 'Atrial Remodeling', 'Cardiac Imaging Techniques', 'Female', 'Fluorodeoxyglucose F18', 'Heart Atria', 'Humans', 'Male', 'Middle Aged', 'Pilot Projects', 'Positron Emission Tomography Computed Tomography', 'Radiopharmaceuticals'] | 30,191,438 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067.198', 'C23.550.073.198'], ['C23.300.052', 'C23.550.113', 'G09.330.040.800'], ['E01.370.350.130'], ['D09.254.229.500'], ['A07.541.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.7... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ICD function and dysfunction in patients with arrhythmogenic cardiac diseases: the role of home monitoring. | BACKGROUND: Since their implementation in clinical practice, remote home monitoring systems (HM) have undoubtedly become an added value in patients with implantable devices for cardiac rhythm management. The aim of this study was to investigate the impact of HM on clinical management and outcome in patients with channe... | ['Adult', 'Arrhythmias, Cardiac', 'Belgium', 'Defibrillators, Implantable', 'Early Diagnosis', 'Electrocardiography, Ambulatory', 'Electrophysiologic Techniques, Cardiac', 'Equipment Failure Analysis', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Remote Consultation', 'Treatment Outcome'] | 24,187,765 | [['M01.060.116'], ['C14.280.067', 'C23.550.073'], ['Z01.542.115'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E01.390'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['E01.370.370.380.245', 'E01.370.405.267'], ['E05.325.192'], ['E05.318.372.500.750.249', 'N05.715.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Alloimmune neonatal neutropenia. | In three neonates, the diagnosis of anti-NA1 alloimmune neutropenia related to maternal immunization against fetal polymorphonuclear leukocytes (PMN) antigens was achieved by serum antibody screening and PMN phenotyping. All the children were small for date and exhibited bacterial infection within days 2-13. Neutropeni... | ['Adult', 'Autoantigens', 'Female', 'Granulocytes', 'Humans', 'Immunization, Passive', 'Immunophenotyping', 'Infant, Newborn', 'Isoantibodies', 'Isoantigens', 'Leukocyte Transfusion', 'Neutropenia'] | 2,029,073 | [['M01.060.116'], ['D23.050.422'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['M01.060.703... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Hypersensitivity vasculitis and granulomatous hepatitis induced by glybenclamide: a case report (author's transl)]. | The second case in the medical literature of hypersensitivity vasculitis induced by glybenclamide is reported, and for the first time vasculitic lesions are demonstrated in the histopathological study of liver tissue. The case was a male patient admitted because of a febrile illness and generalized malaise of long dura... | ['Diabetes Mellitus', 'Drug Hypersensitivity', 'Glyburide', 'Granuloma', 'Hepatitis', 'Humans', 'Male', 'Middle Aged', 'Vasculitis, Leukocytoclastic, Cutaneous'] | 6,776,355 | [['C18.452.394.750', 'C19.246'], ['C20.543.206', 'C25.100.468'], ['D02.065.950.828.575', 'D02.886.590.795.575'], ['C15.604.515.292', 'C23.550.382'], ['C06.552.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.907.940.910', 'C20.543.520.910']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Test-retest reliability of a web-based colour vision test]. | BACKGROUND: Screening tests should be simple, with high acceptance, low costs and offer a high sensitivity and specificity as well as high reliability. The test-retest reliability of a web-based colour vision test was evaluated.METHOD: The results of 386 subjects, who had performed the web-based colour vision test with... | ['Color Perception Tests', 'Diagnosis, Computer-Assisted', 'Feasibility Studies', 'Humans', 'Internet', 'Mass Screening', 'Patient Satisfaction', 'Reproducibility of Results'] | 20,602,298 | [['E01.370.380.850.150'], ['E01.158', 'L01.313.500.750.100.158'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Long-term treatment of clarithromycin at a low concentration improves hydrogen peroxide-induced oxidant/antioxidant imbalance in human small airway epithelial cells by increasing Nrf2 mRNA expression. | BACKGROUND: Clarithromycin (CAM), a representative macrolide antibiotic, has been used widely at low doses for long-term therapy of chronic inflammatory airway diseases. Anti-inflammatory effects of macrolide antibiotics were first discovered in clinical practice. Although oxidative stress is known as a key pathogenesi... | ['Antioxidants', 'Cell Survival', 'Cells, Cultured', 'Clarithromycin', 'Dose-Response Relationship, Drug', 'Epithelial Cells', 'Gene Expression', 'Humans', 'Hydrogen Peroxide', 'Interleukin-8', 'NF-E2-Related Factor 2', 'Oxidants', 'RNA, Messenger', 'Respiratory Mucosa', 'Time Factors', 'Treatment Outcome'] | 28,235,416 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.346'], ['A11.251'], ['D02.540.576.500.992.100'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Transport of water and solutes across sheep visceral pleura. | The fluid and solute transport properties of pleural tissue were studied using specimens of intact visceral pleura from adult sheep lungs. After thoracotomy, a shallow incision through the pleural surface permitted 10-cm2 by 10-micrometer pieces of visceral pleura free of lung parenchyma to be peeled off the lung surfa... | ['Animals', 'Biological Transport', 'Body Water', 'Diffusion', 'Hemoglobins', 'Hydrostatic Pressure', 'In Vitro Techniques', 'Permeability', 'Pleura', 'Sheep', 'Sodium'] | 507,515 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CAG repeat polymorphism in the androgen receptor gene in women with rheumatoid arthritis. | OBJECTIVE: Rheumatoid arthritis (RA) is the most common chronic, autoimmune, inflammatory disease, with a genetic and hormonal background. The prevalence of women among patients with RA suggests the important role of sex hormones in the pathogenesis of RA. We examined the association between CAG repeat polymorphism in ... | ['Alleles', 'Arthritis, Rheumatoid', 'Case-Control Studies', 'Female', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Male', 'Polymorphism, Genetic', 'Receptors, Androgen', 'Trinucleotide Repeats'] | 22,089,459 | [['G05.360.340.024.340.030'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795'], ['D12.776.826.750.150'... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of olfactory dysfunction on sensory evaluation and preparation of foods. | Aim of this study was to investigate the impact of olfactory dysfunction on behavior during sensory evaluation and self-preparation, as well as on sensory perception and pleasantness of green tea and coffee. We compared the intensities of overall odor, flavor, and bitter taste, respectively, and the pleasantness rating... | ['Adolescent', 'Adult', 'Aged', 'Behavior', 'Coffee', 'Cooking', 'Female', 'Humans', 'Middle Aged', 'Odorants', 'Olfaction Disorders', 'Olfactory Perception', 'Sensation', 'Taste', 'Tea'] | 19,619,597 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145'], ['D20.215.784.249', 'G07.203.100.325', 'J02.200.325'], ['J01.576.423.200.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G16.500.275.640', 'N06.230.480'], ['C10.597.751.600', 'C23.888.592.763.550'], ['F02.463.593.485'], ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Separation and other stress in child abuse. | 80 children who had been abused by their parents or caretakers were examined for separation experience early in life and for other stress factors within their families. Although early separation of parent and infant was common in abusing families, combinations of other stresses and conflicts were also present. These we... | ['Anxiety, Separation', 'Child Abuse', 'Child, Preschool', 'Family', 'Female', 'Humans', 'Infant', 'Male', 'Mother-Child Relations', 'Obstetric Labor Complications', 'Pregnancy', 'Social Class', 'Stress, Psychological'] | 6,103,310 | [['F03.080.300', 'F03.625.047'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['M01.060.406.448'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.829.263.370.290.170'], ['C13.703.420'], ['G08.686.784.769'], ['I01.880.853.996.755', 'N01.824.782'], [... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Low initial dose of levothyroxine for treatment of congenital hypothyroidism]. | OBJECTIVE: To evaluate the results of treatment of infants with congenital hypothyroidism (CH) with a low initial dosage of levothyroxine.METHODS: 138 newborns with primary CH detected by neonatal screening were divided into 3 groups according to levels of serum TSH, TT(3) and TT(4): sub-clinical CH (TSH >50 mU/L), mil... | ['Congenital Hypothyroidism', 'Female', 'Humans', 'Hypothyroidism', 'Infant, Newborn', 'Male', 'Thyrotropin', 'Thyroxine', 'Triiodothyronine'] | 15,940,798 | [['C05.116.099.343.347', 'C05.116.132.256', 'C16.320.240.625', 'C19.297.155', 'C19.874.482.281'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['M01.060.703.520'], ['D06.472.699.631.525.883', 'D12.644.548.691.525.883'], ['D06.472.931.812', 'D12.125.072.050.767'], ['D06.472.931.740.385', 'D12.125.07... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Calcium influx and intracellular stores in angiotensin II stimulation of normal and hyperplastic pituitary cells. | In rat pituitary cells from estrogen-induced hyperplasia, angiotensin II (ANG II) does not evoke a clear spike elevation of intracellular Ca2+ concentration ([Ca2+]i) but induces a plateau increase. The present work was undertaken to establish whether this difference was related to a differential participation of intra... | ['Angiotensin II', 'Animals', 'Calcium', 'Calcium Channel Blockers', 'Calcium Channels, L-Type', 'Female', 'Hyperplasia', 'Inositol 1,4,5-Trisphosphate', 'Intracellular Membranes', 'Pituitary Gland', 'Potassium', 'Rats', 'Rats, Sprague-Dawley', 'Reference Values', 'Thapsigargin'] | 10,484,357 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150.400', 'D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selection of items for a computer-adaptive test to measure fatigue in patients with rheumatoid arthritis: a Delphi approach. | PURPOSE: Computer-adaptive tests (CATs) can measure precisely at individual level with few items selected from an item bank. Our aim was to select fatigue items to develop a CAT for rheumatoid arthritis (RA) and include expert opinions that are important for content validity of measurement instruments.METHODS: Items we... | ['Arthritis, Rheumatoid', 'Consensus', 'Delphi Technique', 'Expert Testimony', 'Fatigue', 'Female', 'Health Status Indicators', 'Humans', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Psychometrics'] | 21,805,365 | [['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['F01.829.316.068', 'F02.463.785.373.433'], ['L01.906.197'], ['I01.880.604.583.232', 'N03.706.535.253'], ['C23.888.369'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.11... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
A combination of extended fuzzy AHP and fuzzy GRA for government E-tendering in hybrid fuzzy environment. | The recent government tendering process being conducted in an electronic way is becoming an inevitable affair for numerous governmental agencies to further exploit the superiorities of conventional tendering. Thus, developing an effective web-based bid evaluation methodology so as to realize an efficient and effective ... | ['Algorithms', 'Models, Theoretical'] | 25,057,506 | [['G17.035', 'L01.224.050'], ['E05.599']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Is health insurance affordable for the uninsured? | In this paper, we investigate the meaning of "affordability" in the context of health insurance. Assessing the relationship between the affordability of coverage and the large number of uninsured in the U.S. is important for understanding the barriers to purchasing coverage and evaluating the role of policy in reducing... | ['Adult', 'Empirical Research', 'Female', 'Humans', 'Insurance, Health', 'Male', 'Medically Uninsured', 'Middle Aged', 'Models, Econometric', 'Socioeconomic Factors', 'United States'] | 16,806,543 | [['M01.060.116'], ['H01.770.644.241'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['M01.385'], ['M01.060.116.630'], ['E05.318.740.500.600.500', 'E05.599.835.890.500', 'N05.715.360.750.530.500.500', 'N06.850.520.830.500.600.500'], ['I01.880.853.996', 'N01.824'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Cytokines induced by Sendai virus in human peripheral blood leukocytes. | Human peripheral blood leukocytes (hPBL) are a rich source of natural leukocyte interferon (IFN-alpha) when treated with Sendai virus. Sendai virus treatment of hPBL will also result in significant production of several chemokines and cytokines such as macrophage inflammatory protein-1alpha (MIP-1alpha), MIP-1beta, RAN... | ['Chemokine CCL2', 'Chemokine CCL3', 'Chemokine CCL4', 'Cytokines', 'Humans', 'In Vitro Techniques', 'Interferon-alpha', 'Interferon-gamma', 'Interleukins', 'Leukocytes', 'Macrophage Colony-Stimulating Factor', 'Macrophage Inflammatory Proteins', 'Monokines', 'Parainfluenza Virus 1, Human', 'Tumor Necrosis Factor-alpha... | 8,699,116 | [['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D12.644.276.374.200.110.150', 'D12.644.276.374.200.600.150', 'D12.776.467.374.200.110.150', 'D12.776.467.374.200.600.150', 'D23.125.300.110.150', 'D23.125.300.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular risk stratification in advanced heart failure patients. | Risk stratification in advanced heart failure (HF) is crucial for the individualization of therapeutic strategy, in particular for heart transplantation and ventricular assist device implantation. We tested the hypothesis that cardiac gene expression profiling can distinguish between HF patients with different disease ... | ['Bias', 'Cluster Analysis', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Heart Failure', 'Humans', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Risk Assessment'] | 19,793,385 | [['N05.715.350.150', 'N06.850.490.500'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.393.332'], ['G05.308'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.740... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
1alpha,25-Dihydroxyvitamin D3 enhances proliferation of rat prostate cancer cells in the presence of living bone. | 1alpha,25-Dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)) is known to inhibit prostate cancer cells in vitro. Its effects on proliferation in the presence of living bone have not been reported, but are especially relevant since much of the morbidity and mortality associated with prostate cancer is due to metastatic bone d... | ['Animals', 'Bone and Bones', 'Calcitriol', 'Cell Line', 'Cell Proliferation', 'Cell Survival', 'Coculture Techniques', 'Male', 'Prostatic Neoplasms', 'Rats'] | 17,210,249 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E05.481.500.374'], ['C04.588.945.440.770', 'C12.294.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bombesin receptors as a novel anti-anxiety therapeutic target: BB1 receptor actions on anxiety through alterations of serotonin activity. | The effects of PD 176252 [3-(1H-indol-3-yl)-N-[1-(5-methoxy-pyridin-2-yl)-cyclohexylmethyl]-2-methyl-2-[3-(nitro-phenyl)ureido]propionamide], a nonpeptide bombesin (BB) BB1/BB2 receptor antagonist, were assessed in rats using several ethologically relevant tests of anxiety. Consistent with a role for the bombesin famil... | ['Animals', 'Anti-Anxiety Agents', 'Anxiety', 'Drug Delivery Systems', 'Female', 'Guinea Pigs', 'Indoles', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Bombesin', 'Serotonin'] | 17,035,523 | [['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['F01.470.132'], ['E02.319.300'], ['B01.050.150.900.649.313.992.550'], ['D03.633.100.473'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D12.776.543.750.695.070', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemophilic pseudotumor: spectrum of MR findings. | OBJECTIVE: To determine the MR imaging appearance of hemophilic pseudotumor (HP) and its clinical implications.DESIGN AND PATIENTS: Five hemophilic patients (aged 35-77 years) with 12 HPs in various anatomic locations were included in this study. The MR images were retrospectively evaluated for the appearance of the le... | ['Adult', 'Aged', 'Hematoma', 'Hemophilia A', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Muscular Diseases', 'Retrospective Studies'] | 9,297,751 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.414.838'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C16.320.099.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C05.651', 'C10.668.491'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.75... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Role 2 Afloat custodian. | The Role 2 Afloat (R2A) capability is now firmly established on several maritime platforms using the 370 Module (afloat) equipment.
This year has seen the appointment on board ships that support R2A of a new full-time role, the Medical Module Manager
(MMM), who is responsible for the equipment on board. This article ou... | ['Humans', 'Military Personnel', 'Mobile Health Units', 'Naval Medicine', 'Ships', 'United Kingdom', 'Workforce'] | 30,088,732 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.625'], ['N02.278.421.702', 'N02.421.726.233.628'], ['H02.403.560'], ['J01.937.817'], ['Z01.542.363'], ['N04.452.525']] | ['Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
[Clinical research and humanitarian work: the role of M?decins sans Fronti?res in the fight against malaria]. | In the 1990s and in the absence of data, M?decins sans frontiers (MSF) initiated a series of in vivo clinical studies to measure antimalarial efficacy and optimise treatment strategies within its missions. Between 1996 and 2004, more than 12,000 patients were enrolled in 43 studies in 18 countries of Asia and Africa. T... | ['Altruism', 'Developing Countries', 'Ethics, Medical', 'Humans', 'Malaria', 'Physicians', 'Research', 'World Health Organization'] | 19,361,396 | [['F01.145.813.090'], ['I01.615.500.300'], ['K01.752.566.479.171.132.750', 'N05.350.340.162.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530', 'C01.920.875'], ['M01.526.485.810', 'N02.360.810'], ['H01.770.644'], ['N03.540.514.718.800']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
The development of coordination via joint expectations for shared benefits. | People frequently need to cooperate despite having strong self-serving motives. In the current study, pairs of 5- and 7-year-olds (N = 160) faced a one-shot coordination problem: To benefit, children had to choose the same of 3 reward divisions. They could not communicate or see each other and thus had to accurately pr... | ['Child', 'Child Behavior', 'Child Development', 'Choice Behavior', 'Cooperative Behavior', 'Female', 'Humans', 'Male', 'Reward'] | 32,338,934 | [['M01.060.406'], ['F01.145.179'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.785.373.346'], ['F01.145.813.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.770.836']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Glycopeptide antibiotic analogs for selective inactivation and two-photon imaging of vancomycin-resistant strains. | A novel theranostic divalent vancomycin analog using a planar 1,8-diazapyrene moiety as a rigid scaffold exhibits potent and selective antibacterial activity against Gram (+) bacteria including vancomycin-resistant strains, while having minimal influence on Gram (-) bacteria and mammalian cells. Moreover, this theranos... | ['Animals', 'Anti-Bacterial Agents', 'Glycopeptides', 'Gram-Positive Bacteria', 'Humans', 'Microbial Sensitivity Tests', 'Microscopy, Electrochemical, Scanning', 'Molecular Structure', 'Optical Imaging', 'Vancomycin Resistance'] | 26,953,360 | [['B01.050'], ['D27.505.954.122.085'], ['D09.400.420', 'D12.644.233'], ['B03.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E01.370.350.515.666.450', 'E05.595.666.450'], ['G02.111.570', 'G02.466'], ['E01.370.350.589', 'E05.642'], ['G06.099.225.98... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Understanding the experience and manifestation of depression among Korean immigrants in New York City. | Depression among immigrant groups, especially Korean immigrants, has often lacked a comprehensive understanding by the providers of Western health care. This study aims to explore the subjective experience of Korean immigrants suffering from depression during resettlement in the United States. A series of focus groups ... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Aged', 'Cultural Competency', 'Culture', 'Depression', 'Emigrants and Immigrants', 'Female', 'Focus Groups', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Interviews as Topic', 'Korea', 'Male', 'Middle Aged', 'New York City', 'Psychometrics', 'Surveys and Ques... | 19,822,885 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['I01.880.853.100.364'], ['I01.076.201.450', 'I01.880.853.100'], ['F01.145.126.350'], ['M01.189'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Use of occupations and activities in a modified constraint-induced movement therapy program: a musician's triumphs over chronic hemiparesis from stroke. | OBJECTIVE: This case report addresses the use of therapeutic occupations and activities within a modified constraint-induced movement therapy (mCIMT) approach for a 52-yr-old female violinist 4 yr after ischemic stroke.METHOD: Analysis of occupational performance was completed before and after intervention using a modi... | ['Brain Infarction', 'Chronic Disease', 'Exercise Therapy', 'Female', 'Humans', 'Middle Aged', 'Music', 'Occupational Health', 'Occupational Therapy', 'Paresis', 'Stroke Rehabilitation'] | 21,073,104 | [['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['C23.550.291.500'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['K01.602'], ['N0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Humanities [K]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of volatile sulphur compounds production at individual gingival crevicular sites in humans. | The present investigation describes a method for collection and analysis of volatile sulphur compounds (VSC) from gingival crevicular sites in humans. Tenax-GC trapping devices were used to adsorb and concentrate VSC from crevicular air at -55 degrees C, which were then thermally desorbed at 120 degrees C. Gas chromato... | ['Adult', 'Aged', 'Breath Tests', 'Chromatography, Gas', 'Disulfides', 'Female', 'Gingival Pocket', 'Gingivitis', 'Halitosis', 'Humans', 'Hydrogen Sulfide', 'Male', 'Middle Aged', 'Sulfhydryl Compounds', 'Sulfides'] | 1,306,680 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.100'], ['E05.196.181.349'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['C01.408.360', 'C07.465.714.258.480.360'], ['C01.408', 'C07.465.714.258.480'], ['C23.888.821.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.260.340', 'D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Attitudes to over-the-counter analgesics among 15-16 year-old teenagers]. | BACKGROUND: More information is needed on teenagers' attitudes to self-medication with OTC-analgesics, and their access to medicine and information.MATERIAL AND METHOD: An anonymous questionnaire study was performed among all tenth grade students in Drammen, a middle sized city in Norway, in spring 2007.RESULTS: 367 st... | ['Adolescent', 'Analgesics', 'Attitude to Health', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Nonprescription Drugs', 'Norway', 'Pain', 'Parents', 'Self Medication', 'Sex Factors', 'Surveys and Questionnaires'] | 19,690,593 | [['M01.060.057'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['F01.100.150', 'N05.300.150'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.530'], ['Z01.542.816.374'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['F01.829.263.500.320', 'I01.880.853... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Regulatory effects of apoptosis-associated speck-like protein on cytokines in the P388D1 macrophage-like cell line. | Apoptosis-associated speck-like protein (ASC) is an adaptor molecule of caspase-1 activation that stimulates the secretion of multiple pro-inflammatory cytokines. We investigated the regulatory effects of ASC in the P388D1 macrophage-like cell line. Data showed that ASC overexpression induced by pEGFP-ASC-C2 transfecti... | ['Animals', 'Apoptosis Regulatory Proteins', 'CARD Signaling Adaptor Proteins', 'Caspase 1', 'Cell Line', 'Cytokines', 'Cytoskeletal Proteins', 'Enzyme Activation', 'Gene Expression', 'Gene Expression Regulation', 'Gene Silencing', 'Macrophages', 'Mice', 'RNA Interference'] | 23,064,768 | [['B01.050'], ['D12.644.360.075', 'D12.776.476.075'], ['D12.644.360.024.131', 'D12.644.360.075.358', 'D12.776.157.057.006', 'D12.776.476.024.139', 'D12.776.476.075.358'], ['D08.811.277.656.262.500.126.550.100', 'D08.811.277.656.300.200.126.550.100', 'D12.644.360.075.405.550.100', 'D12.776.476.075.405.550.100'], ['A11.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.