Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Bullet embolism with radiologic documentation. A case report. | A case of bullet embolism is reported wherein a handgun missile, fired during a "shoot-out," perforated (among other structures) the anterior and posterior walls of the thoracic aorta, rebounded into the aortic lumen, and was transported to the left femoral artery where it came to rest. Roentgenographic study was instr... | ['Embolism', 'Forensic Medicine', 'Humans', 'Male', 'Radiography', 'Wounds, Gunshot'] | 6,496,439 | [['C14.907.355.350'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['C26.986.900']] | ['Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Insulin signaling in various equine tissues under basal conditions and acute stimulation by intravenously injected insulin. | The aim of the study was to analyze key proteins of the equine insulin signaling cascade and their extent of phosphorylation in biopsies from muscle tissue (MT), liver tissue (LT), and nuchal AT, subcutaneous AT, and retroperitoneal adipose tissues. This was investigated under unstimulated (B1) and intravenously insuli... | ['Adipose Tissue', 'Animals', 'Female', 'Horses', 'Injections, Intravenous', 'Insulin', 'Insulin Resistance', 'Liver', 'Male', 'Muscle, Skeletal', 'Phosphorylation', 'Receptor, Insulin', 'Signal Transduction'] | 28,595,108 | [['A10.165.114'], ['B01.050'], ['B01.050.150.900.649.313.984.235.472'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['A03.620'], ['A02.633.567', 'A10.690.552.500'], ['G02.111.665', 'G02.607.780', 'G03.796... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of inflammation or disconnection from peripheral target tissue on the capsaicin sensitivity of rat dorsal root ganglion sensory neurones. | Dorsal root ganglion (DRG) sensory neurones from adult rats are known to lose their capsaicin sensitivity in vitro if they are cultured without nerve growth factor (NGF). Here we show similar results following peripheral nerve transection in vivo, which deprives DRG sensory neurones of target-derived NGF. By measuring ... | ['Animals', 'Biological Transport', 'Calcium', 'Capsaicin', 'Cells, Cultured', 'Denervation', 'Drug Resistance', 'Ganglia, Spinal', 'Inflammation', 'Ion Channel Gating', 'Ion Channels', 'Nerve Growth Factors', 'Neurons, Afferent', 'Peripheral Nerve Injuries', 'Rats', 'Rats, Sprague-Dawley', 'Sciatic Nerve'] | 8,834,108 | [['B01.050'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10.251.355.325.190'], ['A11.251'], ['E04.525.210'], ['G07.690.773.984'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.35... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polymerization properties of two normally circulating fibrinogens, HMW and LMW. Evidence that the COOH-terminal end of the a-chain is of importance for fibrin polymerization. | The plasma fibrinogen fractions HMW (mw 340,000) and LMW (mw 305,000) were prepared from purified (beta-alanine precipitated) fibrinogen by step-wise precipitation with ammonium sulfate. The thrombin clotting times were 14" and 20" respectively. The enzymatic phase of coagulation, measured as release of fibrinopeptide-... | ['Fibrin', 'Fibrinogen', 'Fibrinopeptide A', 'Humans', 'Kinetics', 'Light', 'Macromolecular Substances', 'Molecular Weight', 'Scattering, Radiation', 'Thrombin Time'] | 4,082,102 | [['D12.776.124.270'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D12.644.200', 'D12.776.124.125.515', 'D12.776.124.270.310', 'D12.776.811.300.310', 'D23.101.340', 'D23.119.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['G01.358.500.505.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Molecular epidemiological study of human coronavirus OC43 in Shanghai from 2009-2016]. | Objective: To understand the epidemiological characteristics of Human coronavirus (HCoV), the patterns of emergence and circulation, and the genotype distribution of human coronavirus OC43 (HCoV-OC43) from November, 2009 to April, 2016 in Shanghai. Methods: A total of 6 059 respiratory specimens, including pharyngeal s... | ['China', 'Coronavirus Infections', 'Coronavirus OC43, Human', 'Epidemiologic Studies', 'Genotype', 'Humans', 'Middle East Respiratory Syndrome Coronavirus', 'Phylogeny', 'Respiratory Tract Infections', 'Sequence Analysis, DNA'] | 29,334,709 | [['Z01.252.474.164'], ['C01.925.782.600.550.200'], ['B04.820.578.500.540.150.113.500.500'], ['E05.318.372.500', 'N05.715.360.330.500', 'N06.850.520.450.500'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.578.500.540.150.113.750'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['C01.748', 'C08.73... | ['Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
[Prevention of accidents caused by construction work]. | Descriptive data on occupational accidents and diseases in the field of construction and particularly among builders are reported. They derive from publications of the National Insurance Institute for Occupational Accidents (INAIL) and refer to the Italian and Umbrian situation. Data show that the number and the severi... | ['Accidents, Occupational', 'Humans', 'Italy', 'Risk', 'Safety'] | 2,484,490 | [['N06.850.135.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800'], ['N06.850.135.060.075']] | ['Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Scatterer reconstruction and parametrization of homogeneous tissue for ultrasound image simulation. | Numerical simulation of ultrasound images can facilitate the training of sonographers. A realistic appearance of simulated ultrasonic speckle is essential for a plausible ultrasound simulation. An efficient and realistic model for ultrasonic speckle is the convolution of the ultrasound point-spread function with a para... | ['Computer Simulation', 'Image Processing, Computer-Assisted', 'Models, Biological', 'Phantoms, Imaging', 'Ultrasonography'] | 26,737,745 | [['L01.224.160'], ['L01.224.308'], ['E05.599.395'], ['E07.671'], ['E01.370.350.850']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Quality of life after cerebrovascular stroke: a systematic study of patients' preferences for different functional outcomes. | OBJECTIVES: To elicit valid quality of life estimates and the highest acceptable treatment risk of different outcomes after stroke. This is a prerequisite for rational medical decision-making, especially when considering treatments like thrombolysis.SUBJECTS: Healthy people, non-stroke medical patients and stroke survi... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Cerebrovascular Disorders', 'Decision Support Techniques', 'Female', 'Humans', 'Male', 'Marital Status', 'Middle Aged', 'Quality of Life', 'Recurrence', 'Treatment Outcome'] | 10,475,999 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300', 'C14.907.253'], ['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500', 'I01.240.361.500', 'I01.880.853.150.423.500', 'N01.224.361.500', 'N01.8... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
An alternative method to amplify RNA without loss of signal conservation for expression analysis with a proteinase DNA microarray in the ArrayTube format. | BACKGROUND: Recent developments in DNA microarray technology led to a variety of open and closed devices and systems including high and low density microarrays for high-throughput screening applications as well as microarrays of lower density for specific diagnostic purposes. Beside predefined microarrays for specific ... | ['Cells, Cultured', 'Computer Systems', 'DNA Primers', 'DNA Probes', 'Gene Expression Profiling', 'Humans', 'Microarray Analysis', 'Nucleic Acid Amplification Techniques', 'Oligonucleotide Array Sequence Analysis', 'Peptide Hydrolases', 'Polymerase Chain Reaction', 'Reproducibility of Results', 'Staining and Labeling'] | 16,768,788 | [['A11.251'], ['L01.224.230'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.588.570'], ['E05.393.620'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.66... | ['Anatomy [A]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Virus infections and chronic rheumatic disorders. | There is little direct evidence that viruses cause inflammatory arthritis in the sense that infectious agents classically cause disease. However, there are several mechanisms by which virus infections could be implicated in the pathogenesis of such disorders. In particular virus infection of lymphocytes could produce t... | ['Antigens, Viral', 'Arthritis, Infectious', 'Arthritis, Rheumatoid', 'Connective Tissue Diseases', 'Humans', 'Hypersensitivity', 'Lymphoproliferative Disorders', 'T-Lymphocytes, Regulatory', 'Virus Diseases'] | 6,217,974 | [['D23.050.327'], ['C01.100', 'C05.550.114.099'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['C17.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['C15.604.515', 'C20.683.515'], ['A11.118.637.555.567.550.500.700', 'A11.118.637.555.567.569.200.700', 'A11.118.637.555.567.5... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Demeclocycline-induced phosphate diabetes in a patient with inappropriate ADH secretion and systemic sarcoidosis. | We report a case of phosphate diabetes in a patient with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with sarcoidosis. Our patient was affected by systemic sarcoidosis and he fits the criteria of Schwartz for the diagnosis of SIADH. He presented with phosphate diabetes which appea... | ['Demeclocycline', 'Humans', 'Hypophosphatemia, Familial', 'Inappropriate ADH Syndrome', 'Male', 'Middle Aged', 'Sarcoidosis'] | 8,450,917 | [['D02.455.426.559.847.562.900.185', 'D04.615.562.900.185'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.815.647', 'C13.351.968.419.815.647', 'C16.320.565.618.544', 'C16.320.831.647', 'C18.452.648.618.544', 'C18.452.750.400.500'], ['C10.228.140.617.738.320', 'C18.452.950.626', 'C19.700.490'], ['M01.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gunshot wounds caused by modern firearms in the light of our investigations. | The experiment was carried out on 27 sheep with traumatic-haemorrhagic shock caused by a gunshot wound produced using high-velocity missiles from the HM16 rifle. Sixty minutes after injury treatment with blood-replacing fluids was started. In Group I Ringer's solution with sodium lactate pH 8.2 was infused, Group II re... | ['Animals', 'Blood Substitutes', 'Firearms', 'Isotonic Solutions', "Ringer's Lactate", "Ringer's Solution", 'Sheep', 'Shock, Hemorrhagic', 'Shock, Traumatic', 'Wounds, Gunshot'] | 3,339,682 | [['B01.050'], ['D27.505.954.502.140', 'J01.637.087.249'], ['J01.637.870.350'], ['D26.776.498'], ['D26.776.498.500.500'], ['D26.776.498.750'], ['B01.050.150.900.649.313.500.380.791'], ['C23.550.414.980', 'C23.550.835.650'], ['C23.550.835.888', 'C26.797'], ['C26.986.900']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Endovascular repair of complex aortic aneurysms: intravascular ultrasound guidance with an intracardiac probe. | To assess the accuracy and efficacy of intravascular ultrasound guidance obtained by an intracardiac ultrasound probe during complex aortic endografting. Between November 1999 and July 2002, 19 patients (5 female, 14 male; mean age 73.5 +/- 2.1 years) underwent endovascular repair of thoracic (n = 10), complex abdomina... | ['Aged', 'Aortic Aneurysm, Abdominal', 'Aortic Aneurysm, Thoracic', 'Echocardiography', 'Female', 'Humans', 'Male', 'Reproducibility of Results', 'Ultrasonography, Interventional'] | 14,753,303 | [['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Combining Alcohol with Benzodiazepines or Psychostimulants. Metaphoric Meanings and the Concept of Control in the Online Talk of Polydrug Use. | The co-administration of different substances is a widespread practice in the context of hard drug use. Among others, alcohol combined with certain substances produces potentially dangerous interactions. This article explores how people who combine alcohol with benzodiazepines or psychostimulants perceive these practic... | ['Adult', 'Benzodiazepines', 'Central Nervous System Depressants', 'Central Nervous System Stimulants', 'Drug Interactions', 'Ethanol', 'Finland', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Metaphor', 'Online Social Networking', 'Qualitative Research', 'Risk-Taking', 'Self-Control', 'Social Behavior', 'Substan... | 31,547,794 | [['M01.060.116'], ['D03.633.100.079.080'], ['D27.505.696.277', 'D27.505.954.427.210'], ['D27.505.696.282', 'D27.505.954.427.220'], ['G07.690.773.968'], ['D02.033.375'], ['Z01.542.816.186'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.400.899.500', 'K01.752.798.500'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
[The influence of polyvitamin complex polijen on mutagenic and cytotoxic effect of copper oxychloride in white mice]. | The present study investigates antimutagenic and anticytotoxic effect of polyvitamin complex Polijen in laboratory mice. Mutation in mice was induced by pesticide - copper oxychloride 3Cu(OH)2 CuCl2 , which is characterizes by the mutagenic and cytotoxic effect. Introduction of copper oxychloride (dosage 1/2, 1/5, 1/10... | ['Animals', 'Chromosome Aberrations', 'Copper', 'Disease Models, Animal', 'Mice', 'Mutation', 'Treatment Outcome', 'Vitamins'] | 18,633,151 | [['B01.050'], ['C23.550.210', 'G05.365.590.175'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.590'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['D27.505.696.494.600', 'G07.203.30... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The impact of community context on children's health and nutritional status in China. | The link between community environment and individual health outcomes has been widely documented in Western literature, but little is known about whether community context influences children's health over and above individual characteristics in developing countries. This study examines how community socioeconomic stat... | ['Adolescent', 'Body Height', 'Child', 'Child Health', 'China', 'Environment', 'Female', 'Health Status', 'Health Surveys', 'Humans', 'Male', 'Nutritional Status', 'Residence Characteristics', 'Rural Population', 'Sex Factors', 'Social Class', 'Urban Population'] | 28,285,233 | [['M01.060.057'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['M01.060.406'], ['N01.400.225'], ['Z01.252.474.164'], ['G16.500.275', 'N06.230'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.52... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Isolation and Western Blotting of Latex-Bead Phagosomes to Track Phagosome Maturation. | Phagocytosis plays an essential role in the immune system for the defense against invading microorganisms and the clearing of apoptotic cells. After internalization, the newly formed phagosome is constantly remodeled by fusion with early endosomes, late endosomes, and lysosomes. These changes ultimately deliver the eng... | ['Animals', 'Blotting, Western', 'Cell Fractionation', 'Electrophoresis, Polyacrylamide Gel', 'Immunoblotting', 'Mice', 'Microspheres', 'Phagocytosis', 'Phagosomes', 'RAW 264.7 Cells'] | 27,815,884 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.242.251'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.320', 'E05.601.470.320'], ['B01.050.150.900.649.313.992.635.505.500'], ['E07.565'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Individuals with pulmonary tuberculosis have lower levels of circulating CD1d-restricted NKT cells. | Mycobacterium tuberculosis (MTB) is a leading cause of mortality worldwide from an infectious agent. Natural killer T (NKT) cells recognize mycobacterial antigens and contribute to anti-MTB immunity in mouse models. NKT cells were measured in subjects with pulmonary tuberculosis, MTB-exposed individuals, and healthy co... | ['Adult', 'Antigens, CD1', 'Antigens, CD1d', 'Case-Control Studies', 'Female', 'Flow Cytometry', 'Humans', 'Killer Cells, Natural', 'Leukocytes, Mononuclear', 'Male', 'Mycobacterium tuberculosis', 'Tuberculosis, Pulmonary'] | 17,397,008 | [['M01.060.116'], ['D23.050.301.264.035.100', 'D23.050.301.264.894.080', 'D23.101.100.110.100', 'D23.101.100.894.080'], ['D23.050.301.264.035.100.500', 'D23.050.301.264.894.080.500', 'D23.101.100.110.100.500', 'D23.101.100.894.080.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Recurrent deep neck abscess and piriform sinus tract: a 15-year review on the diagnosis and management. | BACKGROUND: Piriform sinus tract (PST) is a rare congenital condition. A delay in diagnosis is common leading to recurrent inflammation.METHOD: A retrospective review was performed on all cases of PST treated at a tertiary referral centre between May 1997 and May 2012.RESULTS: Eighteen patients were reviewed with a mea... | ['Abscess', 'Adolescent', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Drainage', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Neck', 'Pyriform Sinus', 'Recurrence', 'Retrospective Studies', 'Thyroiditis, Suppurative', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 25,092,087 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['E02.309', 'E04.237'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A01.598... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Linking planning performance and gray matter density in mid-dorsolateral prefrontal cortex: moderating effects of age and sex. | Planning of behavior relies on the integrity of the mid-dorsolateral prefrontal cortex (mid-dlPFC). Yet, only indirect evidence exists on the association of protracted maturation of dlPFC and continuing gains in planning performance post adolescence. Here, gray matter density of mid-dlPFC in young, healthy adults (18-3... | ['Adolescent', 'Adult', 'Age Factors', 'Brain Mapping', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Prefrontal Cortex', 'Problem Solving', 'Sex Factors', 'Thinking', 'Young Adult'] | 22,921,922 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], ['A08.186.211.200.885.287.500... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Psychiatric comorbidity and 30-day readmissions after hospitalization for heart failure, AMI, and pneumonia. | OBJECTIVE: In 2012, the Centers for Medicare and Medicaid Services implemented a policy that penalizes hospitals for "excessive" all-cause hospital readmissions within 30 days after discharge from an index hospitalization for heart failure (HF), acute myocardial infarction (AMI), and pneumonia. The aim of this study wa... | ['Adult', 'Aged', 'Comorbidity', 'Female', 'Heart Failure', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Myocardial Infarction', 'Patient Readmission', 'Pneumonia', 'Time Factors', 'United States'] | 25,642,610 | [['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['E02.760.400.620', 'N02.421.585.400.620'], ['C01.748.610',... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Nurse managers' strategies for feeling less drained by their work: an action research and reflection project for developing emotional intelligence. | AIMS: To raise nurse managers' critical awareness of practice problems; uncover practice constraints and improve work effectiveness.BACKGROUND: Nurse management requires skills and knowledge, underscored by emotional intelligence. The research improved participants' practice and personal insights.METHODS: Purposive sam... | ['Adaptation, Psychological', 'Attitude of Health Personnel', 'Awareness', 'Burnout, Professional', 'Emotional Intelligence', 'Female', 'Health Services Research', 'Humans', 'Nurse Administrators', 'Nursing Staff, Hospital', 'Problem Solving'] | 24,655,218 | [['F01.058'], ['F01.100.050', 'N05.300.100'], ['F02.463.188.150'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['F01.752.543.500'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.070.670', 'M01.526.485.650.580', 'N02.360.650.580'], ['... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Heart Valve Disease Awareness Survey 2017: what did we achieve since 2015? | AIMS: The 2015 Heart Valve Disease Awareness Survey showed a low knowledge and awareness about heart valve disease in the general population despite its high prevalence and morbidity. The 2017 survey was conducted to re-evaluate concern and knowledge about heart valve disease after 2 years of rapidly increasing patient... | ['Awareness', 'Europe', 'Female', 'Heart Valve Diseases', 'Humans', 'Male', 'Middle Aged', 'Patient Education as Topic', 'Prevalence', 'Retrospective Studies', 'Surveys and Questionnaires'] | 29,943,272 | [['F02.463.188.150'], ['Z01.542'], ['C14.280.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I02.233.332.500', 'N02.421.726.407.680'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.372.500.500.500', 'E05.318.372... | ['Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Demonstration of eosinophil degranulation on the surface of opsonized schistosomules by phase-contrast cinemicrography. | Phase-contrast cinephotomicrography was used to examine eosinophil-schistosomule interaction. Eosinophil degranulation against the surface of schistosomules was observed in the presence of immune serum. | ['Cytoplasmic Granules', 'Eosinophils', 'Motion Pictures', 'Opsonin Proteins', 'Schistosoma mansoni'] | 730,347 | [['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['J01.897.280.500.598', 'K01.093.545', 'L01.178.590.500', 'L01.178.820.090.598'], ['D12.776.124.486.485.114.767', 'D12.776.124.486.657', 'D12.776.124.790.651.114... | ['Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Effects of spatially varying selection on nucleotide diversity and linkage disequilibrium: insights from deer mouse globin genes. | An important goal of population genetics is to elucidate the effects of natural selection on patterns of DNA sequence variation. Here we report results of a study to assess the joint effects of selection, recombination, and gene flow in shaping patterns of nucleotide variation at genes involved in local adaptation. We ... | ['Alleles', 'Animals', 'Cloning, Molecular', 'Diploidy', 'Genetic Variation', 'Genetics, Population', 'Genome', 'Globins', 'Linkage Disequilibrium', 'Models, Genetic', 'Models, Theoretical', 'Multigene Family', 'Nucleotides', 'Peromyscus', 'Recombination, Genetic'] | 18,716,337 | [['G05.360.340.024.340.030'], ['B01.050'], ['E05.393.220'], ['G05.700.264'], ['G05.365'], ['H01.158.273.343.335'], ['G05.360.340'], ['D12.776.422.316'], ['G05.348.500'], ['E05.599.395.397'], ['E05.599'], ['G05.360.340.024.340.645'], ['D09.408.620', 'D13.695'], ['B01.050.150.900.649.313.992.635.075.500.510'], ['G05.728'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of biofilm in irrigation pipes on microbial quality of irrigation water. | AIMS: The focus of this work was to investigate the contribution of native Escherichia coli to the microbial quality of irrigation water and to determine the potential for contamination by E. coli associated with heterotrophic biofilms in pipe-based irrigation water delivery systems.METHODS AND RESULTS: The aluminium p... | ['Agricultural Irrigation', 'Biofilms', 'Escherichia coli', 'Water Microbiology', 'Water Quality', 'Water Supply'] | 22,150,421 | [['J01.040.044'], ['A20.593', 'G06.120'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['N06.850.460.350.080.750', 'N06.850.460.790.730'], ['J01.293.821.500']] | ['Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Spontaneously ruptured intraspinal epidermoid cyst causing chemical meningitis. | We report a 53-year-old woman with a rare ruptured lumbar intraspinal epidermoid cyst causing chemical meningitis evaluated with MRI (including diffusion-weighted imaging), with histopathologic correlation. | ['Central Nervous System Cysts', 'Diffusion Magnetic Resonance Imaging', 'Epidermal Cyst', 'Female', 'Humans', 'Meningitis', 'Middle Aged', 'Rupture'] | 22,249,012 | [['C04.588.614.250.387', 'C10.500.142', 'C10.551.240.375', 'C16.131.666.142'], ['E01.370.350.825.500.150'], ['C04.182.254'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.614'], ['M01.060.116.630'], ['C26.761']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development. | Protein degradation by the ubiquitin-proteasome system is critical for neuronal function. Neurons utilize microtubule-dependent molecular motors to allocate proteasomes to synapses, but how proteasomes are coupled to motors and how this is regulated to meet changing demand for protein breakdown remain largely unknown. ... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Axonal Transport', 'Axons', 'Cytoplasm', 'Cytoplasmic Dyneins', 'Humans', 'Mice', 'Microtubules', 'Neurons', 'Proteasome Endopeptidase Complex', 'Proteins', 'Proteolysis', 'Proteostasis', 'Synapses', 'p38 Mitogen-Activated Protein Kinases'] | 31,327,739 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['G03.143.355.040', 'G04.392.040', 'G11.561.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A11.284.430.214'], ['D08.811.277.040.025.193.249.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Discovery of fairy circles in Australia supports self-organization theory. | Vegetation gap patterns in arid grasslands, such as the "fairy circles" of Namibia, are one of nature's greatest mysteries and subject to a lively debate on their origin. They are characterized by small-scale hexagonal ordering of circular bare-soil gaps that persists uniformly in the landscape scale to form a homogene... | ['Biomass', 'Feedback, Physiological', 'Grassland', 'Models, Biological', 'Namibia', 'Plant Development', 'Poaceae', 'Rain', 'Western Australia'] | 26,976,567 | [['G16.500.275.157.100', 'N06.230.124.100'], ['G07.410.732'], ['G16.500.275.157.531', 'N06.230.124.390'], ['E05.599.395'], ['Z01.058.290.175.580'], ['G07.345.625', 'G15.589'], ['B01.650.940.800.575.912.250.822'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.5... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Randomized controlled trial on the influence of dietary intervention on epigenetic mechanisms in children with cow's milk allergy: the EPICMA study. | Epigenetic mechanisms could drive the disease course of cow's milk allergy (CMA) and formula choice could modulate these pathways. We compared the effect of two different dietary approaches on epigenetic mechanisms in CMA children. Randomized controlled trial on IgE-mediated CMA children receiving a 12-month treatment ... | ['Animals', 'CD4-Positive T-Lymphocytes', 'Caseins', 'Cattle', 'Child', 'DNA Methylation', 'Epigenesis, Genetic', 'Female', 'Forkhead Transcription Factors', 'Humans', 'Hydrolysis', 'Immune System', 'Lactobacillus rhamnosus', 'Male', 'Milk Hypersensitivity', 'Probiotics'] | 30,808,949 | [['B01.050'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['B01.050.150.900.649.313.500.380.271'], ['M01.060.406'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G05.308.203'], ['D12.776.260.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Training of working memory in children with ADHD. | Working memory (WM) capacity is the ability to retain and manipulate information during a short period of time. This ability underlies complex reasoning and has generally been regarded as a fixed trait of the individual. Children with attention deficit hyperactivity disorder (ADHD) represent one group of subjects with ... | ['Adolescent', 'Adult', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Cognition', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Memory', 'Neuropsychological Tests', 'Task Performance and Analysis', 'Treatment Outcome'] | 12,424,652 | [['M01.060.057'], ['M01.060.116'], ['F03.625.094.150'], ['M01.060.406'], ['F02.463.188'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F04.711.513'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Preparation and antioxidant activity of Lycium barbarum oligosaccharides. | In this study, the Lycium barbarum oligosaccharides (LBO) were prepared by hydrolysis using hydrogen peroxide (H₂O₂). The yield of the LBO was monitored during the hydrolysis process. The hydrolysis conditions were optimized as follows: time, 4h; temperature, 70 °C; and H₂O₂ concentration, 2.5% (v/v). The hydrolysates ... | ['Antioxidants', 'Hot Temperature', 'Hydrogen Peroxide', 'Hydrolysis', 'Hydroxyl Radical', 'Lycium', 'Oligosaccharides', 'Oxidation-Reduction', 'Powders', 'Solubility', 'Water'] | 24,274,555 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G02.380'], ['D01.04... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Assessment of hepatic blood flow using continuous infusion of high clearance drugs. | AIMS: To provide methods for the translation of the concentration-time profile of highly cleared marker compounds into the underlying clearance and hepatic blood flow profile.METHODS: Continuous infusion of indocyanine green or sorbitol was used to assess the effect of the hepatic blood flow modifiers exercise, somatos... | ['Coloring Agents', 'Exercise', 'Half-Life', 'Hormone Antagonists', 'Hormones', 'Humans', 'Indicators and Reagents', 'Indocyanine Green', 'Infusions, Intravenous', 'Liver Circulation', 'Metabolic Clearance Rate', 'Models, Biological', 'Octreotide', 'Somatostatin', 'Sorbitol'] | 9,643,619 | [['D27.720.233'], ['G11.427.410.698.277', 'I03.350'], ['G01.910.405'], ['D06.347', 'D27.505.696.399.450'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['D03.633.100.473.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['G09.330.100.881.552'], ['E01.370... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[Pathogenesis of retrobulbar neuritis]. | Biological fluids from 146 patients with retrobulbar neuritis were examined for the biochemical, immunochemical and immunologic characteristics that mirror destructive processes in myelin and changes in the system of the cholinoglycine cycle which is one of the stages of the synthesis of myelin in the oligodendrocyte. ... | ['Humans', 'Leucyl Aminopeptidase', 'Multiple Sclerosis', 'Myelin Proteins', 'Myelin Sheath', 'Oligodendroglia', 'Optic Nerve', 'Optic Neuritis'] | 1,326,167 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.350.100.511', 'D08.811.277.656.350.555.700', 'D08.811.277.656.675.555.700'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['D12.776.543.620', 'D12.776.631.580'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.8... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spider web glue: two proteins expressed from opposite strands of the same DNA sequence. | The various silks that make up the web of the orb web spiders have been studied extensively. However, success in prey capture depends as much on the web glue as on the fibers. Spider silk glue, which is considered one of the strongest and most effective biological glues, is an aqueous solution secreted from the orb wea... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'DNA', 'Insect Proteins', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Sequence Homology, Amino Acid', 'Spiders'] | 19,731,928 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D13.444.308'], ['D12.776.093.500'], ['L01.453.245.667'], ['E05.393.620.500'], ['G02.111.810.200', 'G05.810.200'], ['B01.050.500.131.166.803']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
TeleMedMail: free software to facilitate telemedicine in developing countries. | Telemedicine offers the potential to alleviate the severe shortage of medical specialists in developing countries. However lack of equipment and poor network connections usually rule out video-conferencing systems. This paper describes a software application to facilitate store-and-forward telemedicine by email of imag... | ['Computer Communication Networks', 'Computer Security', 'Developing Countries', 'Forecasting', 'Medical Records Systems, Computerized', 'Programming Languages', 'Software', 'Telemedicine'] | 11,604,848 | [['L01.224.230.110'], ['L01.224.134', 'N04.452.910.200'], ['I01.615.500.300'], ['I01.320'], ['E05.318.308.940.968.625', 'L01.313.500.750.300.695', 'N04.452.859.564.650', 'N05.715.360.300.715.500.530', 'N06.850.520.308.940.968.625'], ['L01.224.900.780'], ['L01.224.900'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.8... | ['Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Severe maternal psychopathology and infant-mother attachment. | Eighty-two mother-infant dyads, comprising women with psychiatric disorder and individually matched controls, were followed up over the children's 1st year of life. The mothers with mental illness consisted of two subgroups: first, 25 severely mentally ill mothers who had been admitted to a psychiatric unit with their ... | ['Adult', 'Bipolar Disorder', 'Child of Impaired Parents', 'Depressive Disorder, Major', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Mental Disorders', 'Mother-Child Relations', 'Object Attachment', 'Patient Admission', 'Personality Assessment', 'Personality Development', 'Psychotic Disorders'] | 10,847,622 | [['M01.060.116'], ['F03.084.500'], ['M01.106'], ['F03.600.300.375'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F03'], ['F01.829.263.370.290.170'], ['F02.739.794.624'], ['E02.760.400.600', 'N02.421.585.40... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mapping fatty acid binding to beta-lactoglobulin: Ligand binding is restricted by modification of Cys 121. | Native beta-lactoglobulin (Blg) binds 1 mole of palmitic acid per mole of protein with a dissociation constant of 0.6 microM for the primary fatty acid binding site. Chemical modification of Cys 121, which lies at the external putative hydrophobic binding site of Blg, does not affect retinol or 4,4'-bis 1-(phenylamino)... | ['Anilino Naphthalenesulfonates', 'Animals', 'Binding Sites', 'Cattle', 'Cyclic N-Oxides', 'Cysteine', 'Electron Spin Resonance Spectroscopy', 'Fluorescence', 'Fluorescent Dyes', 'Hydrogen-Ion Concentration', 'Lactoglobulins', 'Ligands', 'Methyl Methanesulfonate', 'Methylation', 'Models, Molecular', 'Molecular Structur... | 9,514,270 | [['D02.092.146.125', 'D02.455.426.559.847.638.555.282', 'D02.886.645.600.080.050.650.050', 'D04.615.638.555.282'], ['B01.050'], ['G02.111.570.120'], ['B01.050.150.900.649.313.500.380.271'], ['D03.661.243'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['E05.196.867.519.274'], ['G01.358.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Poststernotomy mediastinitis treated by early surgical intervention]. | Poststernotomy mediastinitis in 67-year-old female was successfully treated by early operation after coronary artery revascularization using bilateral internal mammary arteries and gastroepiploic artery. Wider debridement including sternum, ribs, mediastinal fat and connective tissues, and transfer of rt-pectoralis maj... | ['Aged', 'Debridement', 'Female', 'Humans', 'Mediastinitis', 'Myocardial Revascularization', 'Postoperative Complications', 'Sternum'] | 2,809,322 | [['M01.060.116.100'], ['E04.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.846.187.790'], ['E04.100.376.719', 'E04.928.220.520'], ['C23.550.767'], ['A02.835.232.570.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Competition and growth among Aedes aegypti larvae: Effects of distributing food inputs over time. | Male and female mosquito larvae compete for different subsets of the yeast food resource in laboratory microcosms. Males compete more intensely with males, and females with females. The amount and timing of food inputs alters both growth and competition, but the effects are different between sexes. Increased density in... | ['Aedes', 'Animal Feed', 'Animals', 'Body Size', 'Ecosystem', 'Female', 'Larva', 'Male', 'Population Density', 'Sex Characteristics', 'Species Specificity'] | 33,006,964 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['G16.500.275.157', 'N06.230.124'], ['B05.500.500', 'G07.345.500.550.500.500'], ['N01.224.600', 'N06.850.505.400.600'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Glutamine synthetase in cultured whole retinas from the embryonic chick. Role of protein and RNA syntheses in 4 degrees C storage enhancement. | Glutamine synthetase (GS) activity is enhanced in cultured whole retinas when a 72 h incubation at 37 degrees C is preceded by storage at 4 degrees C for 2-24 h. This enhancement occurs even in the absence of glucocorticoids and is maximal in retinas from 11 to 14 d embryos. In comparison, cortisol-induced increases in... | ['Animals', 'Chick Embryo', 'Cold Temperature', 'Culture Techniques', 'Cycloheximide', 'Deoxyadenosines', 'Glutamate-Ammonia Ligase', 'Hydrocortisone', 'Kinetics', 'Protein Biosynthesis', 'RNA, Messenger', 'Retina', 'Time Factors'] | 6,207,921 | [['B01.050'], ['A13.350.150', 'A16.331.200'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E05.481.500'], ['D03.383.621.808.240'], ['D03.633.100.759.590.138.325', 'D13.570.230.229', 'D13.570.583.138.325'], ['D08.811.464.259.20... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bacterial contamination and septic transfusion reaction rates associated with platelet components before and after introduction of primary culture: experience at a US Academic Medical Center 1991 through 2017. | BACKGROUND: The high incidence of septic transfusion reactions (STRs) led to testing being mandated by AABB from 2004. This was implemented by primary culture of single-donor apheresis platelets (APs) from 2004 and prestorage pooled platelets (PSPPs) from 2007.STUDY DESIGN/METHODS: Platelet (PLT) aliquots were cultured... | ['Academic Medical Centers', 'Adult', 'Bacterial Infections', 'Blood Component Removal', 'Blood Platelets', 'Blood Safety', 'Blood Transfusion', 'Cells, Cultured', 'Child', 'Drug Contamination', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Incidence', 'Platelet Transfusion', 'Primary Cell Culture', 'Ret... | 32,357,261 | [['N02.278.020'], ['M01.060.116'], ['C01.150.252'], ['E02.120'], ['A11.118.188', 'A15.145.229.188'], ['E02.792.833.230.500', 'E05.760.833.230.500', 'N06.850.780.200.450.325'], ['E02.095.135'], ['A11.251'], ['M01.060.406'], ['N06.850.360'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The normal thyroid gland in the scintigram: size and form variants, thyroid dystopia]. | Quantitative data about the size of the normal thyroid gland are presented: height, width and area of the right and left lobe are scintigraphically different. The calculated weight varies depending on the correction factor. Displaced thyroid tissue is found in the center line, whereas iodine accumulating tissue located... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Choristoma', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Organ Size', 'Radionuclide Imaging', 'Reference Values', 'Thyroid Gland', 'Tongue Neoplasms'] | 6,483,624 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['C23.300.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.116.630'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['E01.370.350.7... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tyrosine nitration in human spermatozoa: a physiological function of peroxynitrite, the reaction product of nitric oxide and superoxide. | Tyrosine nitration is a widely used marker of peroxynitrite (ONOO-) produced from the reaction of nitric oxide (NO.) with superoxide (O2(.-)). Since human spermatozoa are able to produce both NO. and O2(.-) during capacitation in vitro, we investigated whether spontaneous tyrosine nitration of proteins occurs in human ... | ['Calcimycin', 'Female', 'Follicular Fluid', 'Humans', 'Ionophores', 'Male', 'Nitric Oxide', 'Peroxynitrous Acid', 'Phosphorylation', 'Proteins', 'Sperm Capacitation', 'Sperm Motility', 'Spermatozoa', 'Superoxides', 'Tyrosine'] | 11,574,660 | [['D03.633.100.221.173'], ['A05.360.319.114.630.535.150', 'A06.300.312.497.535.150', 'A12.207.270.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.562.374', 'D27.720.395'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D01.625.600.800', 'D01.625.700.750'], ['G02.11... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Norepinephrine release in the amygdala after systemic injection of epinephrine or escapable footshock: contribution of the nucleus of the solitary tract. | Several findings based largely on lesions and drug manipulations within the amygdala suggest that norepinephrine (NE) systems in the amygdala contribute to enhancement of memory processes by epinephrine (EPI). However, no studies to date have directly measured changes in the release of NE in the amygdala after EPI inje... | ['Amygdala', 'Animals', 'Arousal', 'Avoidance Learning', 'Brain Mapping', 'Dose-Response Relationship, Drug', 'Fear', 'Injections', 'Lidocaine', 'Male', 'Neural Pathways', 'Norepinephrine', 'Rats', 'Rats, Sprague-Dawley', 'Solitary Nucleus'] | 9,926,823 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['F02.830.104', 'G11.561.035'], ['F02.463.425.097', 'F02.463.785.373.173'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G07.690.773.875', 'G07.690.936.500'], ['F01.470.361'], ['E02.319.267.530'], ['D02.065.199.092... | ['Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Generalized ceroid-lipofuscinosis]. | A histological verified case of late infantil type of generalized ceroid-lipofuscinosis of Jansky-Bielchowsky syndrome is reported. Paroxismal activity provoked by a low frequency fotostimulation or Pampiglione phenomenon is registrated at the E.E.G. An analysis about the clincial findings and a review of the Pampiglio... | ['Cerebellar Ataxia', 'Child, Preschool', 'Electroencephalography', 'Humans', 'Lipidoses', 'Male', 'Optic Atrophy', 'Retinal Degeneration', 'Syndrome'] | 426,389 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interpretation of postvagotomy endoscopic Congo red test results in relation to ulcer recurrence 5 to 12 years after operation. | BACKGROUND: The aim of the present study was to estimate, after vagotomy, the location and extension of residual vagal innervation of the gastric corpus mucosa by using the endoscopic Congo red test (ECRT) and its relation to recurrent ulcer (RU), as well as the results of quantitative gastric acid tests: basal acid ou... | ['Adult', 'Aged', 'Aged, 80 and over', 'Congo Red', 'Duodenal Ulcer', 'Female', 'Follow-Up Studies', 'Gastric Acid', 'Gastric Mucosa', 'Gastroscopy', 'Humans', 'Male', 'Middle Aged', 'Recurrence', 'Risk Factors', 'Staining and Labeling', 'Vagotomy'] | 9,645,775 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.455.426.559.847.638.555.300', 'D02.886.645.600.080.050.650.250', 'D04.615.638.555.300'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A12.200.307.603'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A complication of inferior dental nerve block: temporary ocular palsy]. | An interesting case of temporary ocular palsy, a complication of inferior dental nerve block was reported. Symptom, sign and proper management were described. Several updated literatures on this topic were reviewed and concluded that this complication might be explained by accidental intra-arterial injection of anesthe... | ['Anesthesia, Dental', 'Anesthesia, Local', 'Humans', 'Mandibular Nerve', 'Ophthalmoplegia'] | 2,635,191 | [['E03.155.141', 'E06.045'], ['E03.155.086.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.120.760.500'], ['C10.292.562.750', 'C10.597.622.447', 'C11.590.472', 'C23.888.592.636.447']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ischaemic stroke after exposure to aflibercept: interaction with vitamin K antagonist and/or direct pharmacodynamic effect? | WHAT IS KNOWN AND OBJECTIVE: Vascular endothelial growth factor (VEGF) proteins are involved in the regulation of vascular endothelium, and their inhibition led to the development of a number of drugs used for malignancies or exudative neo-vascular age-related macular degeneration (AMD).CASE SUMMARY: We report a case o... | ['Anticoagulants', 'Drug Interactions', 'Female', 'Humans', 'International Normalized Ratio', 'Intravitreal Injections', 'Macular Degeneration', 'Ranibizumab', 'Receptors, Vascular Endothelial Growth Factor', 'Recombinant Fusion Proteins', 'Stroke', 'Time Factors', 'Vitamin K'] | 25,930,164 | [['D27.505.954.502.119'], ['G07.690.773.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.625.115.320', 'E05.200.625.115.320'], ['E02.319.267.530.475.500'], ['C11.768.585.439'], ['D12.776.124.486.485.114.224.060.868', 'D12.776.124.790.651.114.224.060.868', 'D12.776.377.715.548.114.224.200.868'], ['D... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improving diabetes care and outcomes in a rural primary care clinic. | BACKGROUND: Data have shown that despite the availability of a wide variety of treatment approaches to normalize plasma glucose, the great majority of diabetic patients remain poorly controlled. The goal of a small, rural health care organization that included a critical access hospital and a 25-provider physician grou... | ['Ambulatory Care Facilities', 'Awards and Prizes', 'Diabetes Mellitus, Type 2', 'Glycated Hemoglobin A', 'Hospitals, Rural', 'Humans', 'Multi-Institutional Systems', 'Outcome Assessment, Health Care', 'Practice Guidelines as Topic', 'Primary Health Care', 'Quality Assurance, Health Care', 'Self Care', 'Wisconsin'] | 16,761,788 | [['N02.278.035'], ['K01.150'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['N02.278.421.518'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.540'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'... | ['Health Care [N]', 'Humanities [K]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Liver disease in Felty's syndrome. | Eighteen patients with Felty's syndrome were examined prospectively for the presence of hepatic abnormalities. Twelve patients had abnormal liver histologic features: five with nodular regenerative hyperplasia and seven with portal fibrosis or abnormal lobular architecture. Only seven of the 12 had abnormal liver chemi... | ['Adult', 'Aged', 'Biopsy, Needle', 'Felty Syndrome', 'Female', 'Humans', 'Hyperplasia', 'Liver Diseases', 'Liver Function Tests', 'Male', 'Middle Aged', 'Prognosis', 'Prospective Studies'] | 7,091,172 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C05.550.114.154.389', 'C05.799.114.389', 'C17.300.775.099.389', 'C20.111.199.389'], ['B01.050... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantifying remediation effectiveness under variable external forcing using contaminant rating curves. | Remediation efforts are typically assessed through before-and-after comparisons of contaminant concentrations or loads. These comparisons can be misleading when external drivers, such as weather conditions, differ between the pre- and postremediation monitoring periods. Here, we show that remediation effectiveness may ... | ['California', 'Environmental Monitoring', 'Environmental Restoration and Remediation', 'Geologic Sediments', 'Mercury', 'Mining', 'Nephelometry and Turbidimetry', 'Rain', 'Water Pollutants, Chemical'] | 21,827,186 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N06.850.460.350.080', 'N06.850.780.375'], ['N06.230.080.600', 'N06.850.460.375'], ['G01.311.330', 'G16.500.320'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['J01.576.655.875.500'], ['E05.196.712.650'], ['G16.500.175.859', 'G16.500.275.063.725.3... | ['Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
The mechanism of inhibition by H2 of H2-evolution by hydrogenases. | By analysing the results of experiments carried out with two FeFe hydrogenases and several "channel mutants" of a NiFe hydrogenase, we demonstrate that whether or not hydrogen evolution is significantly inhibited by H2 is not a consequence of active site chemistry, but rather relates to H2 transport within the enzyme. | ['Hydrogen', 'Hydrogenase', 'Iron-Sulfur Proteins', 'Models, Molecular'] | 23,792,933 | [['D01.268.406', 'D01.362.340'], ['D08.811.682.400'], ['D12.776.157.427.374.375', 'D12.776.556.579.374.375'], ['E05.599.595']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fluorofenidone attenuates bleomycin-induced pulmonary inflammation and fibrosis in mice via restoring caveolin 1 expression and inhibiting mitogen-activated protein kinase signaling pathway. | Idiopathic pulmonary fibrosis is a progressive, life-threatening, interstitial lung disease with no effective therapy. In this study, we evaluated the effects of fluorofenidone (FD), a novel pyridone agent, on a murine model of bleomycin-induced pulmonary inflammation and fibrosis. Institute for Cancer Research mice we... | ['Actins', 'Animals', 'Antibiotics, Antineoplastic', 'Bleomycin', 'Bronchoalveolar Lavage', 'Capillary Permeability', 'Caveolin 1', 'Enzyme Activation', 'Fibronectins', 'Gene Expression Regulation', 'Idiopathic Pulmonary Fibrosis', 'JNK Mitogen-Activated Protein Kinases', 'MAP Kinase Signaling System', 'Male', 'Mice', ... | 23,042,199 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D27.505.954.248.106'], ['D09.400.420.110', 'D12.644.233.110'], ['E05.927.100'], ['G03.143.330', 'G09.330.165'], ['D12.644.360.024.264', 'D12.776.157.057.010', 'D12.776.476.024.280', 'D12.776.543.990.100.500', 'D12.776.744.287'], ['G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tailoring treatment for ductal intraepithelial neoplasia of the breast according to Ki-67 and molecular phenotype. | BACKGROUND: The post-surgical management of ductal intraepithelial neoplasia (DIN) of the breast is still a dilemma. Ki-67 labelling index (LI) has been proposed as an independent predictive and prognostic factor in early breast cancer.METHODS: The prognostic and predictive roles of Ki-67 LI were evaluated with a multi... | ['Adult', 'Aged', 'Antineoplastic Agents, Hormonal', 'Breast Neoplasms', 'Carcinoma in Situ', 'Carcinoma, Ductal, Breast', 'Carcinoma, Intraductal, Noninfiltrating', 'Cohort Studies', 'Female', 'Humans', 'Immunohistochemistry', 'Ki-67 Antigen', 'Middle Aged', 'Phenotype', 'Predictive Value of Tests', 'Proportional Haza... | 23,579,208 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248.169'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.240'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['E05.318.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Historical consequences of the infertility of Otto (1815-67) and Amelia (1818-75), first Royal couple of Greece. | After the Greek Independence (1830), the first King, Otto from the Wittelsbach dynasty (Bayer), was married to Amelia from the House of Oldenburg (1836). Their failure to produce an heir to the throne, eagerly expected by the people, contributed much to their abdication in 1862, as an additional factor at the general, ... | ['Famous Persons', 'Female', 'Government', 'Greece', 'History, 19th Century', 'Humans', 'Infertility', 'Male'] | 21,350,083 | [['K01.517.211.506', 'M01.228'], ['I01.409', 'N03.540.348'], ['Z01.542.383'], ['K01.400.504.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365', 'C13.351.500.365']] | ['Humanities [K]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Multiplex fluorescence in situ hybridization identifies novel rearrangements of chromosomes 6, 15, and 18 in primary uveal melanoma. | Uveal melanomas are the commonest ocular tumour of adults and are characterized by reproducible alterations of chromosomes 1, 3, 6 and 8. These alterations are of prognostic relevance and have also be shown to correlate to high risk and low risk metastatic categories of uveal melanoma as defined by micro-array analysis... | ['Adult', 'Aged', 'Aged, 80 and over', 'Chromosome Aberrations', 'Chromosomes, Human, Pair 15', 'Chromosomes, Human, Pair 18', 'Chromosomes, Human, Pair 6', 'Cohort Studies', 'Cytogenetic Analysis', 'Female', 'Humans', 'In Situ Hybridization, Fluorescence', 'Male', 'Melanoma', 'Middle Aged', 'Uveal Neoplasms'] | 16,684,523 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.370.385', 'G05.360.162.520.300.370.385'], ['A11.284.187.520.300.415.430', 'G05.360.162.520.300.415.430'], ['A11.284.187.520.300.325.330', 'G05.360.162.520.300.325.330'], ['E05.318.372.500.750', 'N05... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Histologic regression of localized prostatic tumor with neoadjuvant hormonal therapy]. | OBJECTIVES: To determine the usefulness of preoperative hormone therapy in patients with organ-confined prostatic carcinoma undergoing radical prostatectomy.METHODS: 7 patients with localized prostatic carcinoma are presented. All patients were submitted to radical prostatectomy; 4 had been randomly selected for preope... | ['Adenocarcinoma', 'Aged', 'Androgen Antagonists', 'Combined Modality Therapy', 'Flutamide', 'Gonadotropin-Releasing Hormone', 'Humans', 'Male', 'Middle Aged', 'Prostatectomy', 'Prostatic Neoplasms', 'Remission Induction'] | 9,065,279 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['D06.347.065', 'D27.505.696.399.450.065'], ['E02.186'], ['D02.065.199.420', 'D02.092.146.113.420'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['B01.050.150.900.649.313.988.400.112.4... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Aggressive bladder carcinoma in an HIV-positive man with tetraplegia and neurogenic bladder. | BACKGROUND/OBJECTIVE: Patients with neurogenic bladder secondary to spinal cord injury who are managed long term with an indwelling catheter are known to be at increased risk for transitional cell carcinoma of the bladder. Immunosuppression is a known risk factor for malignancies that often are more aggresSive than tho... | ['Adult', 'Carcinoma', 'HIV Seropositivity', 'Humans', 'Male', 'Quadriplegia', 'Tomography, X-Ray Computed', 'Urinary Bladder Neoplasms', 'Urinary Bladder, Neurogenic'] | 21,675,364 | [['M01.060.116'], ['C04.557.470.200'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.400.500', 'C01.925.813.400.500', 'C20.673.480.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.622.760', 'C23.888.592.636.786'], ['E01.370.350.350.810', 'E01.370.350.600... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of macrophage migration inhibitory factor on corneal sensitivity after laser in situ keratomileusis in rabbit. | PURPOSE: To investigate the effect of macrophage migration inhibitory factor (MIF) on corneal sensitivity after laser in situ keratomileusis (LASIK) surgery.METHODS: New Zealand white rabbits were used in this study. A hinged corneal flap (160-µm thick) was created with a microkeratome, and -3.0 diopter excimer laser a... | ['Animals', 'Epithelium, Corneal', 'Female', 'Humans', 'Interleukin-6', 'Keratomileusis, Laser In Situ', 'Leukemia Inhibitory Factor', 'Macrophage Migration-Inhibitory Factors', 'Models, Animal', 'Nerve Growth Factor', 'Nerve Regeneration', 'Neurotrophin 3', 'RNA, Messenger', 'Rabbits', 'Recovery of Function', 'Sensati... | 24,688,261 | [['B01.050'], ['A09.371.060.217.325', 'A10.272.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['E02.594.480.750', 'E04.014.520.480.750', 'E04.378.500.750', 'E04.540.825.437.374'], ['D12.644.276.374.470', 'D12.776.467.374.470', 'D23.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The prognosis of melanoma patients with metastases to two or more lymph node areas. | The prognosis of melanoma patients who present with metastatic involvement of two or more noncontiguous lymph node regions before the detection of extranodal metastases has not been previously reported. We identified 21 patients with metastatic melanoma in at least two nodal basins in a review of 175 patients with mela... | ['Adolescent', 'Adult', 'BCG Vaccine', 'Combined Modality Therapy', 'Dacarbazine', 'Female', 'Humans', 'Immunotherapy', 'Lomustine', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Melanoma', 'Middle Aged', 'Neoplasm Invasiveness', 'Prognosis', 'Skin Neoplasms', 'Survival Rate'] | 1,867,519 | [['M01.060.057'], ['M01.060.116'], ['D20.215.894.135.825.100'], ['E02.186'], ['D02.925.200', 'D03.383.129.308.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['D02.065.950.594.440', 'D02.654.692.440'], ['E04.446'], ['C04.697.650.560', 'C23.550.727.650.560'], ['C04.557.465.625.650.510', 'C04... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vivo monitoring of extracellular glutamate in the brain with a microsensor. | Recent discoveries have revealed that glutamatergic neurotransmission in the central nervous system is mediated by a dynamic interplay between neurons and astrocytes. To enhance our understanding of this process, the study of extracellular glutamate is crucial. At present, microdialysis is the most frequently used anal... | ['Animals', 'Aspartic Acid', 'Biological Assay', 'Brain', 'Down-Regulation', 'Excitatory Amino Acid Agonists', 'Extracellular Fluid', 'Glutamic Acid', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Male', 'Microelectrodes', 'Molecular Probe Techniques', 'Neurochemistry', 'Potassium Chloride', 'Rats', 'Rats, Wistar', ... | 16,956,598 | [['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['E05.091'], ['A08.186.211'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D27.505.519.625.190.200', 'D27.505.696.577.190.200'], ['A11.284.295.260', 'A12.207.270'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D02.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
A microsatellite genetic linkage map of human chromosome 18. | We isolated nine new microsatellite markers from chromosome 18 and further characterized and mapped eight microsatellites developed in other laboratories. We have constructed a framework linkage map of chromosome 18 that includes 14 microsatellite markers (12 dinucleotide and 2 tetranucleotide) and 2 RFLP markers. Cyto... | ['Base Sequence', 'Chromosomes, Human, Pair 18', 'DNA, Satellite', 'Female', 'Genetic Linkage', 'Heterozygote', 'Humans', 'Male', 'Molecular Sequence Data', 'Mutation', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Recombination, Genetic', 'Sex Characteristics'] | 8,094,374 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.520.300.415.430', 'G05.360.162.520.300.415.430'], ['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['G05.348'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Tissue distribution and urinary excretion of 14C-ethion in goats. | Tissue concentration and elimination and urinary excretion were followed after intravenous injection of 14C-ethion in 12 goats. Tissue levels were determined in two goats after 8 hr and on each of days 1, 3, 7, 14 and 28 after exposure. During the four-week period plasma and all tissues examined (liver, kidney, fat, mu... | ['Animals', 'Carbon Dioxide', 'Chromatography, Thin Layer', 'Feces', 'Female', 'Goats', 'Half-Life', 'Injections, Intravenous', 'Male', 'Organothiophosphorus Compounds', 'Tissue Distribution'] | 1,946,189 | [['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.196.181.400.537'], ['A12.459'], ['B01.050.150.900.649.313.500.380.513'], ['G01.910.405'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D02.705.539', 'D02.886.300'], ['G03.787.917', 'G07.690.725.949']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fluorescence decrease of conjugated polymers by the catalytic activity of horseradish peroxidase and its application in phenolic compounds detection. | We report the fluorescence decrease of the water-soluble ð-ð-conjugated polymer poly(2-methoxy-5-propyloxy sulfonate phenylene vinylene, MPS-PPV) by the catalytic activity of horseradish peroxidase in the presence of H(2)O(2). MPS-PPV acts as a donor substrate in the catalytic cycle of horseradish peroxidase where the ... | ['Acetaminophen', 'Biocatalysis', 'Horseradish Peroxidase', 'Polymers', 'Spectrometry, Fluorescence', 'Spectrophotometry, Ultraviolet'] | 21,341,687 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['G02.111.086', 'G02.130.500', 'G03.105'], ['D08.811.682.732.512'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Standardizing for microsatellite length in comparisons of genetic diversity. | Mutation rates at microsatellites tend to increase with the number of repeats of the motif, leading to higher levels of polymorphism at long microsatellites. To standardize levels of diversity when microsatellites differ in size, we investigate the relationship between tract length and variation and provide a formula t... | ['DNA, Chloroplast', 'Gene Frequency', 'Genetic Variation', 'Magnoliopsida', 'Microsatellite Repeats', 'Models, Genetic', 'Mutation', 'Regression Analysis', 'Tracheophyta'] | 15,723,680 | [['D13.444.308.283.170', 'D13.444.308.435.275'], ['G05.330'], ['G05.365'], ['B01.650.940.800.575.912.250'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['E05.599.395.397'], ['G05.365.590'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['B01.650.940.800.57... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genetic trends of conformation traits and genetic correlations to osteochondrosis in boars. | The objective of our study was to investigate the heritabilities and genetic correlations between traits from a linear exterior assessment system and osteochondrosis (OC) measured by computed tomography (CT), and in addition, to study the genetic trend in a population where the conformation traits have been included in... | ['Animals', 'Bone and Bones', 'Breeding', 'Forelimb', 'Genetic Predisposition to Disease', 'Hindlimb', 'Male', 'Osteochondrosis', 'Swine', 'Swine Diseases', 'Tomography, X-Ray Computed'] | 24,816,139 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['E05.820.150', 'G05.090'], ['A13.395'], ['C23.550.291.687.500', 'G05.380.355'], ['A13.473'], ['C05.116.821'], ['B01.050.150.900.649.313.500.880'], ['C22.905'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outcomes of 447 SCORE® highly congruent mobile-bearing total knee arthroplasties after 5-10 years follow-up. | INTRODUCTION: The goal of mobile-bearing total knee arthroplasties (TKA) with an anatomical trochlea is to reduce polyethylene wear, the risk of loosening, and patellofemoral complications. Rotating mobile-bearing SCORE(®) TKA was designed according to these principles with standard instrumentation for component placem... | ['Aged', 'Arthroplasty, Replacement, Knee', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'France', 'Humans', 'Knee Prosthesis', 'Male', 'Middle Aged', 'Pain Measurement', 'Patient Satisfaction', 'Prosthesis Design', 'Prosthesis Failure', 'Range of Motion, Articular', 'Recovery of Function', 'Retrospective Studies',... | 23,988,419 | [['M01.060.116.100'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Clinical recommendations for diagnosing, treatment and monitoring of patients with endometrial cancer -- Croatian Oncology Society and Croatian Society for Gynecology and Obstetrics as Croatian Medical Association units and Croatian Society of Gynecological Oncology]. | Uterine cancer occurs mainly in postmenopausal women, usually as vaginal bleeding. Following ovarian and cervical cancer it is the third most common cause of female reproductive system cancer death. Diagnosis is set by analyzing samples obtained via hysterectomy with salpingo-oophorectomy and pelvic / paraaortal lympha... | ['Croatia', 'Endometrial Neoplasms', 'Female', 'Humans', 'Hysterectomy', 'Lymph Node Excision', 'Neoplasm Staging', 'Ovariectomy', 'Salpingectomy'] | 24,364,198 | [['Z01.542.248.295'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E04.446'], ['E01.789.625'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.300.680'], ['E04.950.300.715']] | ['Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Changes in cardiac diastolic dimensions precede hypertrophy in early stages of hypertension. | BACKGROUND: Left ventricular hypertrophy (LVH) has been identified as a main target organ change resulting from hypertension, also being a long-term predictor of myocardial infarction, stroke and cardiovascular death. However, very few longitudinal studies exist following the development of LVH in the hypertensive proc... | ['Adult', 'Blood Pressure', 'Body Mass Index', 'Diastole', 'Echocardiography', 'Humans', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Smoking'] | 9,819,015 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Renin-angiotensin-aldosterone system in nephrotic syndrome. | Previous studies on the renin-angiotensin-aldosterone system and fluid volumes in patients with nephrotic syndrome have not considered the nature of the underlying renal lesion. We compared plasma renin concentration (PRC), plasma aldosterone (PA), and plasma volume in three groups of patients: five nephrotic patients ... | ['Adolescent', 'Adult', 'Aldosterone', 'Blood Volume', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nephrotic Syndrome', 'Renin', 'Renin-Angiotensin System', 'Sodium'] | 6,377,881 | [['M01.060.057'], ['M01.060.116'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['G09.188.130', 'G09.330.380.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.777.419.630.643', 'C13.351.968.419.630.643'], ['D08.811.277.656.074.500.780', 'D08.811.277.656.300.048.780', 'D08... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Early human papillomavirus testing predicts residual/recurrent disease after LEEP risk factors for predicting residual disease in high-grade squamous cervical intraepithelial neoplasia following LEEP conization]. | OBJECTIVE: To explore the risk factors for residual/recurrent disease of cervical intraepithelial neoplasia (CIN) 2 or worse after loop electrosurgical excision procedure (LEEP) and the timing point for postoperative follow-up.METHODS: 428 patients with CIN 2 or CIN 3 who were treated with LEEP were retrospectively rev... | ['Biopsy', 'Cervical Intraepithelial Neoplasia', 'Conization', 'Female', 'Humans', 'Neoplasm Recurrence, Local', 'Neoplasm, Residual', 'Papanicolaou Test', 'Papillomaviridae', 'Retrospective Studies', 'Risk Factors', 'Uterine Cervical Neoplasms', 'Vaginal Smears', 'Viral Load'] | 25,924,452 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.240.250'], ['E01.370.225.500.384.100.160', 'E01.370.225.998.054.160', 'E01.370.388.100.160', 'E04.074.160', 'E05.200.500.384.100.160', 'E05.200.998.054.160', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Organic UV filters exposure induces the production of inflammatory cytokines in human macrophages. | Organic ultraviolet (UV) filters, found in many personal care products, are considered emerging contaminants due to growing concerns about potential long-term deleterious effects. We investigated the immunomodulatory effects of four commonly used organic UV filters (2-hydroxy-4-methoxybenzophenone, BP-3; 4-methylbenzyl... | ['Benzophenones', 'Camphor', 'Cell Line', 'Cinnamates', 'Cytokines', 'Humans', 'Interleukin-6', 'Macrophages', 'Molecular Docking Simulation', 'Propiophenones', 'Sunscreening Agents', 'Tumor Necrosis Factor-alpha', 'Water Pollutants, Chemical'] | 29,710,614 | [['D02.455.426.559.389.134', 'D02.522.223'], ['D02.455.426.100.080.050.500.326', 'D02.455.426.100.080.550.234.326', 'D02.455.849.575.141.500.326', 'D02.522.376', 'D04.075.080.500.234.326'], ['A11.251.210'], ['D02.241.223.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A coarse-grain MD (molecular dynamic) simulation of PCL-PEG and PLA-PEG aggregation as a computational model for prediction of the drug-loading efficacy of doxorubicin. | Formulating a hydrophobic drug that is water-soluble is a pharmaceutical challenge. One way is to incorporate the drug in an amphiphilic micelle composed from an aggregation of block copolymers. Design of a good nano-micelle requires many trial-and-error attempts. In this article, we developed a computational model bas... | ['Doxorubicin', 'Drug Delivery Systems', 'Ethylene Oxide', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Lactates', 'Lactones', 'Micelles', 'Molecular Dynamics Simulation', 'Neoplasms', 'Polyethylene Glycols', 'Solubility', 'Water'] | 30,628,852 | [['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E02.319.300'], ['D02.355.291.411.417'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['D02.241.511.459'], ['D02.540'], ['D05.374', 'D26.255.560'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'],... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Technical and policy approaches to balancing patient privacy and data sharing in clinical and translational research. | INTRODUCTION: Clinical researchers need to share data to support scientific validation and information reuse and to comply with a host of regulations and directives from funders. Various organizations are constructing informatics resources in the form of centralized databases to ensure reuse of data derived from sponso... | ['Base Sequence', 'Computer Security', 'Genome-Wide Association Study', 'Genotype', 'Humans', 'Information Dissemination', 'National Institutes of Health (U.S.)', 'Phenotype', 'Privacy', 'Translational Medical Research', 'United States'] | 20,051,768 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['L01.224.134', 'N04.452.910.200'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Effect of noxious tail pinch on the discharge rate of mesocortical and mesolimbic dopamine neurons: selective activation of the mesocortical system. | The effects of noxious tail pinch on the activity of mesocortical and mesolimbic dopamine (DA) neurons located in the ventromedial mesencephalic tegmentum were analyzed in ketamine-anesthetized rats. The great majority of mesocortical DA neurons responded to tail pinch, either by an excitation (65%), or by an inhibitio... | ['Action Potentials', 'Animals', 'Dopamine', 'Electric Stimulation', 'Frontal Lobe', 'Limbic System', 'Male', 'Neural Conduction', 'Neural Pathways', 'Pain', 'Rats', 'Rats, Inbred Strains', 'Tegmentum Mesencephali'] | 2,702,475 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E05.723.402'], ['A08.186.211.200.885.287.500.270'], ['A08.186.211.180'], ['G07.265.753', 'G11.561.601'], ['A08.612'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-performance liquid chromatography tandem mass spectrometry procedure with automated solid phase extraction sample preparation for the quantitative determination of paclitaxel (Taxol) in human plasma. | A sensitive, specific, accurate and reproducible analytical method was developed and validated for the quantitation of the anticancer agent paclitaxel in human plasma. This procedure is based on high performance liquid chromatography/ion spray-tandem mass spectrometry. This methodology is highly specific because a MS/M... | ['Antineoplastic Agents, Phytogenic', 'Chromatography, High Pressure Liquid', 'Humans', 'Indicators and Reagents', 'Mass Spectrometry', 'Paclitaxel', 'Quality Control'] | 9,519,477 | [['D27.505.954.248.179'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['E05.196.566'], ['D02.455.426.392.368.242.888.777', 'D02.455.849.291.850.777'], ['J01.897.608']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Psychoacoustic and experiential determinants of tonal consonance. | Theories of tonal consonance have primarily sought to explain consonance of chords smaller than the octave drawn from the conventional semitone musical scale. Critical evaluation of such theories requires a new body of data. The present study reports consonance ratings for two-tone chords drawn from a quartertone scale... | ['Humans', 'Models, Psychological', 'Music', 'Pitch Perception', 'Psychoacoustics'] | 7,319,993 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['K01.602'], ['F02.463.593.071.700', 'G07.888.125.700'], ['E01.370.382.375.060.530', 'E01.370.685.628', 'F04.096.753.628']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Experimental new automatic tools for robotic stereotactic neurosurgery: towards "no hands" procedure of leads implantation into a brain target. | The use of robotics in neurosurgery and, particularly, in stereotactic neurosurgery, is becoming more and more adopted because of the great advantages that it offers. Robotic manipulators easily allow to achieve great precision, reliability, and rapidity in the positioning of surgical instruments or devices in the brai... | ['Animals', 'Brain', 'Brain Diseases', 'Humans', 'Neurosurgery', 'Reproducibility of Results', 'Robotics', 'Stereotaxic Techniques', 'Swine', 'Therapy, Computer-Assisted'] | 27,194,228 | [['B01.050'], ['A08.186.211'], ['C10.228.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.425'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['E04.525.800', 'E05.873'], ['B01.050.150.900.649.313.500... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
High cystatin C levels predict undesirable outcome for diabetic foot ulcerations. | We investigated the relationship between serum cystatin C levels and the prognosis of diabetic foot ulcerations (DFU). A population-based cohort study involving 1018 patients with type 2 diabetes was conducted. These patients recruited and divided into two groups: nondiabetic foot ulcer group (NDF, n = 865, 85.5%) and ... | ['Aged', 'Asian Continental Ancestry Group', 'Biomarkers', 'China', 'Cystatin C', 'Diabetic Foot', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Physical Examination', 'Predictive Value of Tests', 'Prognosis', 'Prospective Studies', 'Risk Factors', 'Wound Healing'] | 26,864,251 | [['M01.060.116.100'], ['M01.686.508.200'], ['D23.101'], ['Z01.252.474.164'], ['D12.776.215.300'], ['C14.907.320.191', 'C17.800.893.592.450.200', 'C19.246.099.500.191', 'C19.246.099.937.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Subjective reports of cognition in relation to assessed cognitive performance following coronary artery bypass surgery. | Evidence has accumulated to indicate that a proportion of patients who undergo coronary artery bypass surgery (CABS) do develop significant cognitive deficits. This study examines whether those patients who report cognitive deterioration after CABS do show cognitive changes as assessed by neuropsychological testing. Th... | ['Adult', 'Affective Symptoms', 'Aged', 'Attention', 'Cognition', 'Coronary Artery Bypass', 'Female', 'Humans', 'Male', 'Memory', 'Middle Aged', 'Neuropsychological Tests'] | 2,786,075 | [['M01.060.116'], ['F01.145.126.100'], ['M01.060.116.100'], ['F02.830.104.214'], ['F02.463.188'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['M01.060.116.630'], ['F04.711.513']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Osteogenic potential of stem cells-seeded bioactive nanocomposite scaffolds: A comparative study between human mesenchymal stem cells derived from bone, umbilical cord Wharton's jelly, and adipose tissue. | Bone regeneration is considered as an unmet clinical need, the aim of this study is to investigate the osteogenic potential of three different mesenchymal stem cells (MSCs) derived from human bone marrow (BM-MSCs), umbilical cord Wharton's jelly (UC-MSCs), and adipose (AD-MSCs) seeded on a recently developed nanocompos... | ['Adipose Tissue', 'Bone Marrow Cells', 'Cell Separation', 'Female', 'Humans', 'Mesenchymal Stem Cells', 'Nanocomposites', 'Organ Specificity', 'Osteogenesis', 'Tissue Scaffolds'] | 27,862,947 | [['A10.165.114'], ['A11.148', 'A15.378.316'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.830.500', 'A11.872.590.500'], ['J01.637.512.150'], ['G07.650'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['E07.206.627', 'E07.695... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Gadopentetate dimeglumine as an oral negative gastrointestinal contrast agent for MRCP. | BACKGROUND: We investigated the feasibility of using intravenous magnetic resonance (MR) contrast agent as a gastrointestinal oral negative contrast agent to null the bowel signal during MR cholangiopancreatography (MRCP).METHODS: In the first part of the study, a phantom study was performed to select the optimal conce... | ['Biliary Tract Diseases', 'Common Bile Duct', 'Contrast Media', 'Cystic Duct', 'Feasibility Studies', 'Female', 'Gadolinium DTPA', 'Gallbladder', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Pancreatic Diseases', 'Pancreatic Ducts', 'Phantoms, Imaging'] | 10,926,195 | [['C06.130'], ['A03.159.183.079.300'], ['D27.505.259.500', 'D27.720.259'], ['A03.159.183.079.450'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['A03.159.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Persistent diffuse peritonitis in children. | In adults, persistent diffuse peritonitis (PDP) having a special microbiologic spectrum is now defined as a distinct intraabdominal infection because of its aggressive clinical course. Considering also other types of peritonitis, this study was performed to determine characteristics of childhood PDP in regard to clinic... | ['Adolescent', 'Adult', 'Age Distribution', 'Anti-Bacterial Agents', 'Child', 'Child, Preschool', 'Chronic Disease', 'Debridement', 'Drainage', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Intubation, Gastrointestinal', 'Male', 'Peritonitis', 'Retrospective Studies', 'Severity of Illness Index', 'Sex Distribution'... | 9,677,719 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['D27.505.954.122.085'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.500'], ['E04.176'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E02.585.412', 'E05.4... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Implementation of the German guideline for the prevention, diagnosis, treatment and follow-up of non-small cell lung cancer at the Diakoniekrankenhaus Halle/Saale]. | BACKGROUND: More than three years since the release of the german guideline for the prevention, diagnosis, treatment and follow-up of lung cancer the database in terms of the implementation of guideline recommendations is deficient. The aim of this article is to analyze the implementation of the recommended algorithms ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Non-Small-Cell Lung', 'Female', 'Follow-Up Studies', 'Germany', 'Guideline Adherence', 'Humans', 'Lung Neoplasms', 'Male', 'Medical Oncology', 'Practice Guidelines as Topic', 'Pulmonary Medicine'] | 24,222,066 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.315'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Development of a weak-base docetaxel derivative that can be loaded into lipid nanoparticles. | Hydrophobic uncharged drugs such as docetaxel are difficult to encapsulate and retain in liposomal nanoparticles (LNP). In this work we show that a weak base derivative of docetaxel can be actively loaded into LNP using pH gradient loading techniques to achieve stable drug encapsulation and controlled release propertie... | ['Animals', 'Antineoplastic Agents', 'Breast Neoplasms', 'Cryoelectron Microscopy', 'Docetaxel', 'Drug Carriers', 'Drug Compounding', 'Drug Stability', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'Lipids', 'Mice', 'Molecular Structure', 'Nanoparticles', 'Solubility', 'Taxoids', 'Xenograft Model Antitumor Assays'] | 20,202,473 | [['B01.050'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['E01.370.350.515.402.150', 'E05.595.402.150'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'], ['D26.255.260', 'E02.319.300.380'], ['E05.916.270'], ['E05.916.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D10... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Water-bath method for sonographic evaluation of superficial structures of the extremities in children. | High-resolution sonography using a stand-off pad or a gel mound is a standard technique for the evaluation of soft-tissue structures of the hands and feet in children. However, the complex curved surfaces of the hands and feet often yield suboptimal contact between the transducer and the skin. Additionally, the small f... | ['Baths', 'Child', 'Child, Preschool', 'Connective Tissue Diseases', 'Extremities', 'Female', 'Humans', 'Image Enhancement', 'Infant', 'Infant, Newborn', 'Male', 'Ultrasonography'] | 23,478,918 | [['E02.056.110'], ['M01.060.406'], ['M01.060.406.448'], ['C17.300'], ['A01.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['M01.060.703'], ['M01.060.703.520'], ['E01.370.350.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Overexpression of the dopamine receptor-interacting protein Alix/AIP1 modulates NMDA receptor-triggered cell death. | Alix/AIP1 is an adaptor protein involved in apoptosis, endocytic membrane trafficking and brain development. Alix has been found within the human postsynaptic density (PSD) and, since NMDA receptors (NMDARs) are central components of the PSD, we hypothesized that the close proximity of both proteins may allow Alix to i... | ['Animals', 'Calcium-Binding Proteins', 'Cell Cycle Proteins', 'Cell Death', 'Endosomal Sorting Complexes Required for Transport', 'HEK293 Cells', 'Humans', 'Rats', 'Receptors, N-Methyl-D-Aspartate'] | 31,077,357 | [['B01.050'], ['D12.776.157.125'], ['D12.776.167'], ['G04.146'], ['D05.500.199', 'D12.776.543.990.493'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.157.530.400.400.500.500', 'D12.776.543.550.450.500.200.500', 'D12.776.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluating the enantioselective degradation and novel metabolites following a single oral dose of metalaxyl in mice. | Metalaxyl [N-(2,6-dimethylphenyl)-N-(methoxyacetyl)-D,L-alaninemethylester] is a systemic fungicide widely used in agriculture. In this study, the enantioselective distribution, degradation and excretion of metalaxyl were investigated after oral gavage administration of rac-metalaxyl to mice. Concentration of metalaxyl... | ['Administration, Oral', 'Alanine', 'Animals', 'Chromatography, Liquid', 'Feces', 'Fungicides, Industrial', 'Liver', 'Lung', 'Male', 'Mice', 'Mice, Inbred ICR', 'Myocardium', 'Stereoisomerism', 'Tandem Mass Spectrometry'] | 25,454,518 | [['E02.319.267.100'], ['D12.125.042'], ['B01.050'], ['E05.196.181.400'], ['A12.459'], ['D27.720.031.700.288', 'D27.888.723.288'], ['A03.620'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['A02.633.580', 'A07.541.704', 'A10... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Intestinal perforation in Hirschsprung's disease. A clinical case in an adult and review of the literature]. | Hirschsprung's disease is a fairly unusual case, even if not exceptional. For this reason we consider it interesting to present a iatrogenic perforation (of the patient) as a case of Hirschsprung's disease in adult age: the case was treated with urgency, at our surgical department. | ['Adult', 'Age Factors', 'Colonic Diseases', 'Emergencies', 'Female', 'Hirschsprung Disease', 'Humans', 'Intestinal Perforation'] | 9,072,745 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C06.405.469.158'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['C06.198.439', 'C06.405.469.158.701.439', 'C16.131.314.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.557']] | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PBL Core Skills Faculty Development Workshop 3: understanding PBL process assessment and feedback via scenario-based discussions, observation, and role-play. | Tutorial assessment in PBL is thought to be a valid assessment approach and is believed to exert a positive impact on the learning process. Reports, however, have demonstrated that assessment by the facilitator can be unreliable. Training of faculty to conduct this type of assessment has tended to be lacking and is a l... | ['Adult', 'Education', 'Education, Dental', 'Educational Measurement', 'Faculty, Dental', 'Feedback', 'Humans', 'Mentors', 'Problem-Based Learning', 'Staff Development', 'Teaching'] | 18,096,882 | [['M01.060.116'], ['I02'], ['I02.358.274'], ['I02.399'], ['M01.526.485.360', 'M01.526.702.250.273', 'N02.360.360'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.395'], ['F02.463.425.720', 'I02.158.660', 'I02.903.565'], ['I02.574.700', 'N04.452.677.822'], ['I02.903']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
HLA antigens and myasthenia gravis in north India. | The HLA antigen distribution was studied in 37 north Indian patients with myasthenia gravis. The control group consisted of 118 normal, healthy individuals of the same ethnic group. The antigens showing the highest frequency were Bw21 (18.9% vs 4.2% p less than 0.005), Bw35 (24.3% vs 6.8%, p less than 0.005) and A9 (51... | ['Disease Susceptibility', 'Female', 'HLA Antigens', 'Humans', 'India', 'Male', 'Myasthenia Gravis', 'Risk'] | 6,842,252 | [['C23.550.291.687', 'G07.100.250'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['C04.588.614.550.500', 'C04.730.856.490', 'C10.114.656', 'C10.574.781.588', 'C10.668.758.725', 'C20.111.258.500'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.3... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Development and validation of HILIC-ESI/MS/MS methods for simultaneous quantitation of several antipsychotics in human plasma and blood. | BACKGROUND: Knowledge of antipsychotic drug levels at point of care (POC) may significantly aid therapeutic decision-making. To support the development of future POC devices and to validate the use of fingerstick capillary blood sampling, two robust hydrophilic interaction LC-ESI/MS/MS methods were developed and valida... | ['Antipsychotic Agents', 'Blood Chemical Analysis', 'Calibration', 'Chromatography, High Pressure Liquid', 'Half-Life', 'Humans', 'Point-of-Care Systems', 'Reproducibility of Results', 'Spectrometry, Mass, Electrospray Ionization'] | 27,005,848 | [['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E01.370.225.124.100', 'E05.200.124.100'], ['E05.978.155'], ['E05.196.181.400.300'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.442.452.452.680', 'N04.452.515.360.652', 'N04.590.874'], ['E05.318... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Brucella sp. vertebral osteomyelitis with intercurrent fatal Staphylococcus aureus toxigenic enteritis in a bottlenose dolphin (Tursiops truncatus). | A previously beach-stranded, juvenile, male, bottlenose dolphin (Tursiops truncatus) was diagnosed with vertebral osteomyelitis of unknown etiology. Antemortem serological testing suggested past or current Brucella sp. infection; however, this could not be confirmed prior to death despite multiple isolation attempts fr... | ['Animals', 'Bottle-Nosed Dolphin', 'Brucella', 'Brucellosis', 'Enteritis', 'Fatal Outcome', 'Male', 'Osteomyelitis', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 21,908,337 | [['B01.050'], ['B01.050.150.900.649.313.875.267.100'], ['B03.440.400.425.215.500', 'B03.660.050.070.100'], ['C01.150.252.400.167'], ['C06.405.205.462', 'C06.405.469.326'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C01.160.495', 'C05.116.165.495']... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Simple mastectomy under hypnosis: A case study approach. | There is a clear inverse relationship between preoperative anxiety and effective anaesthesia and recovery. Studies have shown that perioperative anxiety can be detrimental to the efficacy of recovery. In order to mitigate the perioperative anaesthetic risk to the patient, perioperative care must be inclusive of psychol... | ['Anesthesia', 'Anxiety', 'Humans', 'Hypnosis', 'Mastectomy, Simple', 'Perioperative Care'] | 29,328,737 | [['E03.155'], ['F01.470.132'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.217', 'F04.754.424'], ['E04.466.754'], ['E02.760.731', 'E04.604', 'N02.421.585.722']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
No germline FH mutations in familial breast cancer patients. | Fumarate hydratase: (FH) was recently identified as the predisposing gene for a tumor predisposition syndrome, hereditary leiomyomatosis and renal cell cancer (HLRCC) (MIM 605839). In HLRCC, individuals with a germline heterozygous mutation in the FH gene typically develop benign leiomyomas of the skin and the uterus (... | ['Breast Neoplasms', 'Female', 'Fumarate Hydratase', 'Genetic Predisposition to Disease', 'Germ-Line Mutation', 'Humans'] | 15,523,491 | [['C04.588.180', 'C17.800.090.500'], ['D08.811.520.241.300.300'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.365.590.350'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Education and lifestyle predict change in dietary patterns and diet quality of adults 55 years and over. | BACKGROUND: Diet is a key risk factor for chronic disease, and an increasing concern among older adults. We aim to examine the changes in dietary patterns using principal component analysis and a diet quality index among older adults and examine the predictors of dietary change over a 4 year period.METHODS: Data was ob... | ['Aged', 'Australia', 'Cohort Studies', 'Diet', 'Diet Surveys', 'Educational Status', 'Female', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Nutritional Status', 'Principal Component Analysis', 'Prospective Studies'] | 31,699,092 | [['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['G07.203.650.240'], ['E05.318.308.980.485.350', 'N05.715.360.300.800.469.300', 'N06.850.505.616.300', 'N06.850.520.308.980.469.350'], ['N01.824.196'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Iodixanol versus Iopromide at Coronary CT Angiography: Lumen Opacification and Effect on Heart Rhythm-the Randomized IsoCOR Trial. | Purpose To show that equal coronary lumen opacification can be achieved with iso- and low-osmolar contrast media when it is injected at the same iodine delivery rate with contemporary cardiac computed tomographic (CT) protocols and to investigate the cardiovascular effect of iso-osmolar contrast media and the image qua... | ['Adult', 'Blood Pressure', 'Computed Tomography Angiography', 'Contrast Media', 'Coronary Angiography', 'Female', 'Heart Rate', 'Humans', 'Iohexol', 'Male', 'Middle Aged', 'Risk Factors', 'Triiodobenzoic Acids'] | 28,809,582 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.810.568', 'E01.370.350.825.810.810.499'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.350.130.625', 'E01.370.350.700.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Meat intake frequency and anemia in Japanese children and adolescents. | The consumption of meat products is considered to be a feasible solution to prevent anemia, which is a critical health problem. The present study assessed hematological parameters and the prevalence of anemia in Japanese children and adolescents, and examined the association with the frequency of meat intake. Data from... | ['Adolescent', 'Anemia', 'Child', 'Cross-Sectional Studies', 'Diet', 'Diet Records', 'Female', 'Humans', 'Japan', 'Male', 'Meat', 'Prevalence'] | 22,435,780 | [['M01.060.057'], ['C15.378.071'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.650.240'], ['N04.452.859.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['G07.203.300.600', 'J02.500.600'], ['E05.318.308.985.525.750'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
A comparison of widowhood and well-being among older Greek and British-Australian migrant women. | The impact of widowhood on well-being has been well-documented, but to date has not focused extensively on the experience of older migrants who have aged in a foreign land. This study aimed to examine the well-being of older migrant widows from two groups in South Australia: British-born (n=61) and Greek-born (n=60) Au... | ['Aged', 'Aged, 80 and over', 'Bereavement', 'Ceremonial Behavior', 'Depressive Disorder', 'Family Relations', 'Female', 'Greece', 'Health Status', 'Humans', 'Loneliness', 'Middle Aged', 'Religion', 'Social Support', 'South Australia', 'Transients and Migrants', 'United Kingdom', 'Widowhood'] | 24,300,071 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.142'], ['F01.145.813.097', 'I01.076.201.450.170'], ['F03.600.300'], ['F01.829.263.370', 'I01.880.853.150.439'], ['Z01.542.383'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.713', 'I01.880.853.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
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