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MH_train_0
MH_train_0
MH_train_0
interacts_with DB00773?
multiple_choice
[ "DB00072", "DB00294", "DB00338", "DB00341", "DB00588", "DB00820", "DB02546", "DB02901", "DB04844" ]
Induction of apoptosis of Beta cells of the pancreas by advanced glycation end-products , important mediators of chronic complications of diabetes mellitus . We herein report cytotoxicity of advanced glycation end-products ( AGEs ) on pancreatic beta cells . AGEs stimulated reactive oxygen species ( ROS ) generation bu...
[ "DB00072" ]
MH_train_1
MH_train_1
MH_train_1
interacts_with DB09079?
multiple_choice
[ "DB00294", "DB00313", "DB00588", "DB00755", "DB00783", "DB02546", "DB02901", "DB06822", "DB08910" ]
Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity . BACKGROUND : Various hormone refractory prostate cancer cell models have been established with androgen depletion and have helped to clarify the mechanism for the transition into androgen-depletion independent...
[ "DB06822" ]
MH_train_2
MH_train_2
MH_train_2
interacts_with DB00083?
multiple_choice
[ "DB00035", "DB00293", "DB00322", "DB00341", "DB00351", "DB00588", "DB00741", "DB00951", "DB01200" ]
Anti-Parkinson 's disease drugs and pharmacogenetic considerations . INTRODUCTION : The development of pharmacogenetic-based clinical practice guidelines for the use of anti-Parkinson 's disease drugs requires , as a pre-requisite , the identification and validation of genetic biomarkers . These biomarkers are then use...
[ "DB00341" ]
MH_train_3
MH_train_3
MH_train_3
interacts_with DB00083?
multiple_choice
[ "DB00619", "DB00630", "DB00783", "DB00819", "DB00989", "DB01067", "DB01171", "DB02546", "DB04844" ]
"A protein chip membrane-capture assay for botulinum neurotoxin activity . Botulinum neurotoxins A a(...TRUNCATED)
[ "DB01171" ]
MH_train_4
MH_train_4
MH_train_4
interacts_with DB06813?
multiple_choice
[ "DB00035", "DB00313", "DB00338", "DB00501", "DB00820", "DB00951", "DB01050", "DB02901", "DB08910" ]
"P21554 cannabinoid receptor deficiency promotes cardiac remodeling induced by pressure overload in (...TRUNCATED)
[ "DB01050" ]
MH_train_5
MH_train_5
MH_train_5
interacts_with DB06288?
multiple_choice
[ "DB00035", "DB00290", "DB00293", "DB00338", "DB00341", "DB00951", "DB01200", "DB01296", "DB02901" ]
"Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of hu(...TRUNCATED)
[ "DB01200" ]
MH_train_6
MH_train_6
MH_train_6
interacts_with DB00862?
multiple_choice
[ "DB00009", "DB00035", "DB00203", "DB00588", "DB00755", "DB00951", "DB02901", "DB04844", "DB06822" ]
"Synthetic delivery system for tuberculosis vaccines : immunological evaluation of the M. tuberculos(...TRUNCATED)
[ "DB00203" ]
MH_train_7
MH_train_7
MH_train_7
interacts_with DB00773?
multiple_choice
[ "DB00290", "DB00452", "DB00630", "DB00783", "DB00977", "DB01067", "DB01656", "DB06779", "DB08910" ]
"Current researches on breast cancer epidemiology in Korea . As a cause of death in women , breast c(...TRUNCATED)
[ "DB01656" ]
MH_train_8
MH_train_8
MH_train_8
interacts_with DB01233?
multiple_choice
[ "DB00015", "DB00341", "DB00741", "DB00820", "DB01576", "DB02546", "DB02901", "DB04844", "DB04905" ]
"Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction that occurs a(...TRUNCATED)
[ "DB04844" ]
MH_train_9
MH_train_9
MH_train_9
interacts_with DB00277?
multiple_choice
[ "DB00338", "DB00351", "DB00459", "DB00588", "DB00820", "DB00989", "DB01182", "DB01259", "DB09068" ]
"Nearly Complete Response of Brain Metastases from P04626 Overexpressing Breast Cancer with DB01259 (...TRUNCATED)
[ "DB01182" ]
End of preview. Expand in Data Studio

Dataset Card for MedHop

With the same format as WikiHop, this dataset is based on research paper abstracts from PubMed, and the queries are about interactions between pairs of drugs. The correct answer has to be inferred by combining information from a chain of reactions of drugs and proteins.

Citation Information

@article{welbl-etal-2018-constructing,
title = Constructing Datasets for Multi-hop Reading Comprehension Across Documents,
author = Welbl, Johannes and Stenetorp, Pontus and Riedel, Sebastian,
journal = Transactions of the Association for Computational Linguistics,
volume = 6,
year = 2018,
address = Cambridge, MA,
publisher = MIT Press,
url = https://aclanthology.org/Q18-1021,
doi = 10.1162/tacl_a_00021,
pages = 287--302,
abstract = {
    Most Reading Comprehension methods limit themselves to queries which
    can be answered using a single sentence, paragraph, or document.
    Enabling models to combine disjoint pieces of textual evidence would
    extend the scope of machine comprehension methods, but currently no
    resources exist to train and test this capability. We propose a novel
    task to encourage the development of models for text understanding
    across multiple documents and to investigate the limits of existing
    methods. In our task, a model learns to seek and combine evidence
    -- effectively performing multihop, alias multi-step, inference.
    We devise a methodology to produce datasets for this task, given a
    collection of query-answer pairs and thematically linked documents.
    Two datasets from different domains are induced, and we identify
    potential pitfalls and devise circumvention strategies. We evaluate
    two previously proposed competitive models and find that one can
    integrate information across documents. However, both models
    struggle to select relevant information; and providing documents
    guaranteed to be relevant greatly improves their performance. While
    the models outperform several strong baselines, their best accuracy
    reaches 54.5 % on an annotated test set, compared to human
    performance at 85.0 %, leaving ample room for improvement.
}
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