id stringlengths 10 13 | question_id stringlengths 10 13 | document_id stringlengths 10 13 | question stringlengths 23 23 | type stringclasses 1
value | choices list | context stringlengths 8.99k 109k | answer sequence |
|---|---|---|---|---|---|---|---|
MH_train_0 | MH_train_0 | MH_train_0 | interacts_with DB00773? | multiple_choice | [
"DB00072",
"DB00294",
"DB00338",
"DB00341",
"DB00588",
"DB00820",
"DB02546",
"DB02901",
"DB04844"
] | Induction of apoptosis of Beta cells of the pancreas by advanced glycation end-products , important mediators of chronic complications of diabetes mellitus . We herein report cytotoxicity of advanced glycation end-products ( AGEs ) on pancreatic beta cells . AGEs stimulated reactive oxygen species ( ROS ) generation bu... | [
"DB00072"
] |
MH_train_1 | MH_train_1 | MH_train_1 | interacts_with DB09079? | multiple_choice | [
"DB00294",
"DB00313",
"DB00588",
"DB00755",
"DB00783",
"DB02546",
"DB02901",
"DB06822",
"DB08910"
] | Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity . BACKGROUND : Various hormone refractory prostate cancer cell models have been established with androgen depletion and have helped to clarify the mechanism for the transition into androgen-depletion independent... | [
"DB06822"
] |
MH_train_2 | MH_train_2 | MH_train_2 | interacts_with DB00083? | multiple_choice | [
"DB00035",
"DB00293",
"DB00322",
"DB00341",
"DB00351",
"DB00588",
"DB00741",
"DB00951",
"DB01200"
] | Anti-Parkinson 's disease drugs and pharmacogenetic considerations . INTRODUCTION : The development of pharmacogenetic-based clinical practice guidelines for the use of anti-Parkinson 's disease drugs requires , as a pre-requisite , the identification and validation of genetic biomarkers . These biomarkers are then use... | [
"DB00341"
] |
MH_train_3 | MH_train_3 | MH_train_3 | interacts_with DB00083? | multiple_choice | [
"DB00619",
"DB00630",
"DB00783",
"DB00819",
"DB00989",
"DB01067",
"DB01171",
"DB02546",
"DB04844"
] | "A protein chip membrane-capture assay for botulinum neurotoxin activity . Botulinum neurotoxins A a(...TRUNCATED) | [
"DB01171"
] |
MH_train_4 | MH_train_4 | MH_train_4 | interacts_with DB06813? | multiple_choice | [
"DB00035",
"DB00313",
"DB00338",
"DB00501",
"DB00820",
"DB00951",
"DB01050",
"DB02901",
"DB08910"
] | "P21554 cannabinoid receptor deficiency promotes cardiac remodeling induced by pressure overload in (...TRUNCATED) | [
"DB01050"
] |
MH_train_5 | MH_train_5 | MH_train_5 | interacts_with DB06288? | multiple_choice | [
"DB00035",
"DB00290",
"DB00293",
"DB00338",
"DB00341",
"DB00951",
"DB01200",
"DB01296",
"DB02901"
] | "Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of hu(...TRUNCATED) | [
"DB01200"
] |
MH_train_6 | MH_train_6 | MH_train_6 | interacts_with DB00862? | multiple_choice | [
"DB00009",
"DB00035",
"DB00203",
"DB00588",
"DB00755",
"DB00951",
"DB02901",
"DB04844",
"DB06822"
] | "Synthetic delivery system for tuberculosis vaccines : immunological evaluation of the M. tuberculos(...TRUNCATED) | [
"DB00203"
] |
MH_train_7 | MH_train_7 | MH_train_7 | interacts_with DB00773? | multiple_choice | [
"DB00290",
"DB00452",
"DB00630",
"DB00783",
"DB00977",
"DB01067",
"DB01656",
"DB06779",
"DB08910"
] | "Current researches on breast cancer epidemiology in Korea . As a cause of death in women , breast c(...TRUNCATED) | [
"DB01656"
] |
MH_train_8 | MH_train_8 | MH_train_8 | interacts_with DB01233? | multiple_choice | [
"DB00015",
"DB00341",
"DB00741",
"DB00820",
"DB01576",
"DB02546",
"DB02901",
"DB04844",
"DB04905"
] | "Chronic daily tadalafil prevents the corporal fibrosis and veno-occlusive dysfunction that occurs a(...TRUNCATED) | [
"DB04844"
] |
MH_train_9 | MH_train_9 | MH_train_9 | interacts_with DB00277? | multiple_choice | [
"DB00338",
"DB00351",
"DB00459",
"DB00588",
"DB00820",
"DB00989",
"DB01182",
"DB01259",
"DB09068"
] | "Nearly Complete Response of Brain Metastases from P04626 Overexpressing Breast Cancer with DB01259 (...TRUNCATED) | [
"DB01182"
] |
End of preview. Expand in Data Studio
Dataset Card for MedHop
With the same format as WikiHop, this dataset is based on research paper abstracts from PubMed, and the queries are about interactions between pairs of drugs. The correct answer has to be inferred by combining information from a chain of reactions of drugs and proteins.
Citation Information
@article{welbl-etal-2018-constructing,
title = Constructing Datasets for Multi-hop Reading Comprehension Across Documents,
author = Welbl, Johannes and Stenetorp, Pontus and Riedel, Sebastian,
journal = Transactions of the Association for Computational Linguistics,
volume = 6,
year = 2018,
address = Cambridge, MA,
publisher = MIT Press,
url = https://aclanthology.org/Q18-1021,
doi = 10.1162/tacl_a_00021,
pages = 287--302,
abstract = {
Most Reading Comprehension methods limit themselves to queries which
can be answered using a single sentence, paragraph, or document.
Enabling models to combine disjoint pieces of textual evidence would
extend the scope of machine comprehension methods, but currently no
resources exist to train and test this capability. We propose a novel
task to encourage the development of models for text understanding
across multiple documents and to investigate the limits of existing
methods. In our task, a model learns to seek and combine evidence
-- effectively performing multihop, alias multi-step, inference.
We devise a methodology to produce datasets for this task, given a
collection of query-answer pairs and thematically linked documents.
Two datasets from different domains are induced, and we identify
potential pitfalls and devise circumvention strategies. We evaluate
two previously proposed competitive models and find that one can
integrate information across documents. However, both models
struggle to select relevant information; and providing documents
guaranteed to be relevant greatly improves their performance. While
the models outperform several strong baselines, their best accuracy
reaches 54.5 % on an annotated test set, compared to human
performance at 85.0 %, leaving ample room for improvement.
}
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