PatSnap/drug · Datasets at Hugging Face

drug_name listlengths 1 3	alias listlengths 1 56 ⌀	target listlengths 1 17	disease listlengths 1 620	drug_type listlengths 1 3	global_highest_dev_status stringclasses 16 values	first_approved_date int64 -872,726,400,000 1,777B	first_approved_indication listlengths 1 21	approval_country listlengths 1 37
[ { "name": "胰酶/纤维素酶/熊去氧胆酸/西甲硅油", "lang": "CN" }, { "name": "Pancreatin/Cellulase/Ursodeoxycholic Acid/Simethicone", "lang": "EN" } ]	null	[ [ { "name": "Bile acid receptor FXR", "lang": "EN" }, { "name": "胆汁酸受体FXR", "lang": "CN" } ] ]	[ [ { "name": "Dyspepsia", "lang": "EN" }, { "name": "消化不良", "lang": "CN" } ] ]	[ "Enzyme" ]	Approved	1,708,560,000,000	[ [ { "name": "Dyspepsia", "lang": "EN" }, { "name": "消化不良", "lang": "CN" } ] ]	[ "South Korea" ]
[ { "name": "甲磺酸阿帕替尼", "lang": "CN" }, { "name": "Apatinib Mesylate", "lang": "EN" } ]	[ { "name": "Apatinib", "lang": "EN" }, { "name": "Rivoceranib", "lang": "EN" }, { "name": "Rivoceranib Mesylate(USAN)", "lang": "EN" }, { "name": "Rivoceranib mesilate", "lang": "EN" } ]	[ [ { "name": "Vascular endothelial growth factor receptor 2", "lang": "EN" }, { "name": "血管内皮细胞生长因子受体2", "lang": "CN" } ] ]	[ [ { "name": "Germline BRCA-mutated, HER2-negative metastatic breast cancer", "lang": "EN" }, { "name": "gBRCA突变/HER2阴性乳腺癌", "lang": "CN" } ], [ { "name": "Hepatocellular Carcinoma", "lang": "EN" }, { "name": "肝细胞癌", "lang": "CN" } ...	[ "Small molecule drug" ]	Pending	1,413,504,000,000	[ [ { "name": "Gastroesophageal junction adenocarcinoma", "lang": "EN" }, { "name": "胃食管交界处腺癌", "lang": "CN" } ], [ { "name": "stomach adenocarcinoma", "lang": "EN" }, { "name": "胃腺癌", "lang": "CN" } ] ]	[ "China" ]
[ { "name": "替本福司", "lang": "CN" }, { "name": "Tebentafusp", "lang": "EN" } ]	[ { "name": "Monoclonal T cell receptor anti-CD3 scFv fusion protein", "lang": "EN" }, { "name": "Tebentafusp-TEBN", "lang": "EN" } ]	[ [ { "name": "T cell surface glycoprotein CD3", "lang": "EN" }, { "name": "T细胞表面糖蛋白CD3复合体", "lang": "CN" } ], [ { "name": "Melanocyte protein PMEL", "lang": "EN" }, { "name": "黑素细胞蛋白PMEL", "lang": "CN" } ] ]	[ [ { "name": "Melanoma", "lang": "EN" }, { "name": "黑色素瘤", "lang": "CN" } ], [ { "name": "Uveal Melanoma", "lang": "EN" }, { "name": "葡萄膜黑色素瘤", "lang": "CN" } ], [ { "name": "Unresectable Melanoma", "lang": "EN" ...	[ "Bispecific T-cell Engager (BiTE)", "TCR fusion protein" ]	Approved	1,643,068,800,000	[ [ { "name": "Uveal Melanoma", "lang": "EN" }, { "name": "葡萄膜黑色素瘤", "lang": "CN" } ] ]	[ "United States", "European Union", "United Kingdom", "Canada", "Australia", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "克林霉素磷酸酯/维A酸", "lang": "CN" }, { "name": "Clindamycin Phosphate/Tretinoin", "lang": "EN" } ]	null	[ [ { "name": "50S ribosomal subunit", "lang": "EN" }, { "name": "50S核糖体亚基", "lang": "CN" } ], [ { "name": "Retinoic acid receptor alpha", "lang": "EN" }, { "name": "维甲酸受体α", "lang": "CN" } ], [ { "name": "Retinoic acid ...	[ [ { "name": "Acne Vulgaris", "lang": "EN" }, { "name": "寻常痤疮", "lang": "CN" } ], [ { "name": "Rosacea", "lang": "EN" }, { "name": "玫瑰痤疮", "lang": "CN" } ] ]	[ "Small molecule drug" ]	Pending	1,162,857,600,000	[ [ { "name": "Acne Vulgaris", "lang": "EN" }, { "name": "寻常痤疮", "lang": "CN" } ] ]	[ "United States", "Australia" ]
[ { "name": "头孢他啶", "lang": "CN" }, { "name": "Ceftazidime", "lang": "EN" }, { "name": "セフタジジム水和物", "lang": "JP" } ]	[ { "name": "CAZ", "lang": "EN" }, { "name": "Ceftazidime (INN)", "lang": "EN" }, { "name": "Ceftazidime Hydrate", "lang": "EN" }, { "name": "Ceftazidime Sodium Carbonate", "lang": "EN" }, { "name": "Ceftazidime and Sodium Chloride", "lang": "EN" }, { "n...	[ [ { "name": "Bacterial penicillin-binding protein", "lang": "EN" }, { "name": "细菌青霉素结合蛋白家族", "lang": "CN" } ] ]	[ [ { "name": "Bacterial Infections", "lang": "EN" }, { "name": "细菌感染", "lang": "CN" } ], [ { "name": "Adnexitis", "lang": "EN" }, { "name": "附件炎", "lang": "CN" } ], [ { "name": "Endocarditis, Bacterial", "lang": "...	[ "Small molecule drug" ]	Withdrawn	410,227,200,000	[ [ { "name": "Gram-Negative Bacterial Infections", "lang": "EN" }, { "name": "革兰氏阴性菌感染", "lang": "CN" } ], [ { "name": "Gram-Positive Bacterial Infections", "lang": "EN" }, { "name": "革兰氏阳性细菌感染", "lang": "CN" } ] ]	[ "China", "Japan" ]
[ { "name": "帕西妥莫单抗", "lang": "CN" }, { "name": "Moxetumomab Pasudotox-TDFK", "lang": "EN" } ]	[ { "name": "Moxetumomab pasudotox", "lang": "EN" }, { "name": "Moxetumomab pasudotox (USAN/INN)", "lang": "EN" }, { "name": "莫塞妥莫单抗", "lang": "CN" } ]	[ [ { "name": "CD22", "lang": "EN" }, { "name": "CD22蛋白", "lang": "CN" } ] ]	[ [ { "name": "Hairy Cell Leukemia", "lang": "EN" }, { "name": "毛细胞白血病", "lang": "CN" } ], [ { "name": "Adult Lymphoblastic Lymphoma", "lang": "EN" }, { "name": "淋巴母细胞淋巴瘤", "lang": "CN" } ], [ { "name": "B-Cell Lymphoma"...	[ "Antibody toxin conjugate" ]	Pending	1,536,796,800,000	[ [ { "name": "Hairy Cell Leukemia", "lang": "EN" }, { "name": "毛细胞白血病", "lang": "CN" } ] ]	[ "United States" ]
[ { "name": "谷胱甘肽/肌苷", "lang": "CN" }, { "name": "Glutathione/Inosine", "lang": "EN" } ]	[ { "name": "Molixan", "lang": "EN" } ]	[ [ { "name": "Beta-nerve growth factor", "lang": "EN" }, { "name": "β-神经生长因子", "lang": "CN" } ] ]	[ [ { "name": "Hepatitis B", "lang": "EN" }, { "name": "乙型肝炎", "lang": "CN" } ], [ { "name": "Hepatitis C", "lang": "EN" }, { "name": "丙型肝炎", "lang": "CN" } ], [ { "name": "Chronic hepatitis C genotype 1", "lang": ...	[ "Small molecule drug" ]	Pending	1,157,846,400,000	[ [ { "name": "Hepatitis C", "lang": "EN" }, { "name": "丙型肝炎", "lang": "CN" } ] ]	[ "Russia" ]
[ { "name": "奥马珠单抗生物类似药(Generium Pharmaceuticals)", "lang": "CN" }, { "name": "Omalizumab biosimilar (Generium Pharmaceuticals)", "lang": "EN" } ]	[ { "name": "Omalizumab Biosimilar", "lang": "EN" }, { "name": "奥马佐单抗生物类似药(Generium Pharmaceuticals)", "lang": "CN" }, { "name": "奥马珠单抗生物类似药", "lang": "CN" } ]	[ [ { "name": "Immunoglobulin E", "lang": "EN" }, { "name": "免疫球蛋白E", "lang": "CN" } ] ]	[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ], [ { "name": "Chronic Urticaria", "lang": "EN" }, { "name": "慢性荨麻疹", "lang": "CN" } ], [ { "name": "Allergic asthma", "lang": "EN" }, ...	[ "Biosimilar", "Monoclonal antibody" ]	Approved	1,644,364,800,000	[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ], [ { "name": "Chronic Urticaria", "lang": "EN" }, { "name": "慢性荨麻疹", "lang": "CN" } ] ]	[ "Russia" ]
[ { "name": "门冬胰岛素 (宜昌东阳光长江药业)", "lang": "CN" }, { "name": "Insulin Aspart Biosimilar (YiChang HEC ChangJiang Pharmaceutical )", "lang": "EN" } ]	null	[ [ { "name": "Insulin receptor", "lang": "EN" }, { "name": "胰岛素受体", "lang": "CN" } ] ]	[ [ { "name": "Diabetes Mellitus", "lang": "EN" }, { "name": "糖尿病", "lang": "CN" } ], [ { "name": "Diabetes Mellitus, Type 2", "lang": "EN" }, { "name": "2型糖尿病", "lang": "CN" } ] ]	[ "Biosimilar", "Peptide Hormone" ]	Pending	1,665,446,400,000	[ [ { "name": "Diabetes Mellitus", "lang": "EN" }, { "name": "糖尿病", "lang": "CN" } ] ]	[ "China" ]
[ { "name": "特丁胺培哚普利", "lang": "CN" }, { "name": "Perindopril Erbumine", "lang": "EN" }, { "name": "ペリンドプリルエルブミン", "lang": "JP" } ]	[ { "name": "Perindopril erbumine (JAN/USP)", "lang": "EN" }, { "name": "Perindopril tert-Butylamine", "lang": "EN" }, { "name": "perindopril", "lang": "EN" }, { "name": "培哚普利", "lang": "CN" }, { "name": "培哚普利叔丁胺", "lang": "CN" }, { "name": "培哚普利叔丁胺盐", ...	[ [ { "name": "Angiotensin-converting enzyme", "lang": "EN" }, { "name": "血管紧张素转化酶", "lang": "CN" } ] ]	[ [ { "name": "Heart Failure", "lang": "EN" }, { "name": "心脏衰竭", "lang": "CN" } ], [ { "name": "Hypertension", "lang": "EN" }, { "name": "高血压", "lang": "CN" } ], [ { "name": "Agranulocytosis", "lang": "EN" }, ...	[ "Small molecule drug" ]	Withdrawn	757,209,600,000	[ [ { "name": "Agranulocytosis", "lang": "EN" }, { "name": "粒细胞减少症", "lang": "CN" } ], [ { "name": "Angioedema", "lang": "EN" }, { "name": "血管性水肿", "lang": "CN" } ], [ { "name": "Cardiovascular Diseases", "lang": "...	[ "China", "Japan", "Canada" ]
[ { "name": "莱博雷生", "lang": "CN" }, { "name": "Lemborexant", "lang": "EN" }, { "name": "レンボレキサント", "lang": "JP" } ]	[ { "name": "DAYVIGOTM", "lang": "EN" }, { "name": "LEM", "lang": "EN" }, { "name": "Lemborexant (JAN/USAN/INN)", "lang": "EN" } ]	[ [ { "name": "Orexin receptor", "lang": "EN" }, { "name": "食欲素受体", "lang": "CN" } ] ]	[ [ { "name": "Sleep Initiation and Maintenance Disorders", "lang": "EN" }, { "name": "入睡和睡眠障碍", "lang": "CN" } ], [ { "name": "Emergence Delirium", "lang": "EN" }, { "name": "苏醒期谵妄", "lang": "CN" } ], [ { "name": "Sleep...	[ "Small molecule drug" ]	Phase 2 Clinical	1,567,468,800,000	[ [ { "name": "Sleep Initiation and Maintenance Disorders", "lang": "EN" }, { "name": "入睡和睡眠障碍", "lang": "CN" } ] ]	[ "United States", "China", "Japan", "Canada", "Australia", "India", "Hong Kong", "Malaysia", "Taiwan Province" ]
[ { "name": "门冬胰岛素生物类似药(Biocon Ltd.)", "lang": "CN" }, { "name": "Insulin aspart-xjhz", "lang": "EN" } ]	[ { "name": "Insulin aspart Biosimilar (Biocon Biologics, Inc.)", "lang": "EN" }, { "name": "Kixelle", "lang": "EN" }, { "name": "门冬胰岛素生物类似药（Biocon Biologics, Inc.）", "lang": "CN" } ]	[ [ { "name": "Insulin receptor", "lang": "EN" }, { "name": "胰岛素受体", "lang": "CN" } ] ]	[ [ { "name": "Diabetes Mellitus", "lang": "EN" }, { "name": "糖尿病", "lang": "CN" } ], [ { "name": "Diabetes Mellitus, Type 1", "lang": "EN" }, { "name": "1型糖尿病", "lang": "CN" } ] ]	[ "Biosimilar", "Peptide Hormone" ]	Discontinued	1,612,483,200,000	[ [ { "name": "Diabetes Mellitus", "lang": "EN" }, { "name": "糖尿病", "lang": "CN" } ] ]	[ "United States", "European Union", "Canada", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "乳酸帕比司他", "lang": "CN" }, { "name": "Panobinostat lactate", "lang": "EN" }, { "name": "パノビノスタット乳酸塩", "lang": "JP" } ]	[ { "name": "Faridak", "lang": "EN" }, { "name": "Panobinostat", "lang": "EN" }, { "name": "Panobinostat lactate (JAN)", "lang": "EN" }, { "name": "panobinostat", "lang": "EN" }, { "name": "panobinostat free base", "lang": "EN" }, { "name": "panobinostat...	[ [ { "name": "Histone deacetylase", "lang": "EN" }, { "name": "组蛋白去乙酰化酶家族", "lang": "CN" } ] ]	[ [ { "name": "Multiple Myeloma", "lang": "EN" }, { "name": "多发性骨髓瘤", "lang": "CN" } ], [ { "name": "Medulloblastoma", "lang": "EN" }, { "name": "髓母细胞瘤", "lang": "CN" } ], [ { "name": "Acute Chest Syndrome", "lang"...	[ "Small molecule drug" ]	Pending	1,424,649,600,000	[ [ { "name": "Multiple Myeloma", "lang": "EN" }, { "name": "多发性骨髓瘤", "lang": "CN" } ] ]	[ "European Union", "Japan", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "洛匹那韦/利托那韦", "lang": "CN" }, { "name": "Lopinavir/Ritonavir", "lang": "EN" }, { "name": "ロピナビル/リトナビル", "lang": "JP" } ]	[ { "name": "ABT-378/Ritonavir", "lang": "EN" }, { "name": "DARE-HPV", "lang": "EN" }, { "name": "LPV/RTV", "lang": "EN" }, { "name": "Lopinavir and Ritonavir", "lang": "EN" }, { "name": "Lopinavir/Ritonavir", "lang": "EN" }, { "name": "利托那韦/洛匹那韦", "...	[ [ { "name": "Human immunodeficiency virus type 1 Pol protein", "lang": "EN" }, { "name": "人类免疫缺陷病毒1型 Pol 蛋白", "lang": "CN" } ] ]	[ [ { "name": "HIV Infections", "lang": "EN" }, { "name": "HIV感染", "lang": "CN" } ], [ { "name": "Human Papillomavirus-Related Cervical Carcinoma", "lang": "EN" }, { "name": "人瘤病毒相关性宫颈癌", "lang": "CN" } ], [ { "name": "H...	[ "Small molecule drug" ]	Discontinued	968,976,000,000	[ [ { "name": "HIV Infections", "lang": "EN" }, { "name": "HIV感染", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "阿立哌唑十二烷酸酯", "lang": "CN" }, { "name": "Aripiprazole Lauroxil", "lang": "EN" } ]	[ { "name": "ALNCD", "lang": "EN" }, { "name": "ARISTADA INITIO", "lang": "EN" }, { "name": "Aripiprazole lauroxil (USAN)", "lang": "EN" } ]	[ [ { "name": "Serotonin 1a (5-HT1a) receptor", "lang": "EN" }, { "name": "5-羟色胺1A受体", "lang": "CN" } ], [ { "name": "Serotonin 2a (5-HT2a) receptor", "lang": "EN" }, { "name": "5-羟色胺2A受体", "lang": "CN" } ], [ { "name": ...	[ [ { "name": "Schizophrenia", "lang": "EN" }, { "name": "精神分裂症", "lang": "CN" } ], [ { "name": "Chronic schizophrenia", "lang": "EN" }, { "name": "慢性精神分裂症", "lang": "CN" } ], [ { "name": "Schizoaffective disorder", ...	[ "Small molecule drug" ]	Pending	1,444,003,200,000	[ [ { "name": "Schizophrenia", "lang": "EN" }, { "name": "精神分裂症", "lang": "CN" } ] ]	[ "United States" ]
[ { "name": "福巴替尼", "lang": "CN" }, { "name": "Futibatinib", "lang": "EN" }, { "name": "フチバチニブ", "lang": "JP" } ]	[ { "name": "Futibatinib (JAN/USAN/INN)", "lang": "EN" }, { "name": "福替巴替尼", "lang": "CN" } ]	[ [ { "name": "Fibroblast growth factor receptor 1", "lang": "EN" }, { "name": "成纤维细胞生长因子受体-1", "lang": "CN" } ], [ { "name": "Fibroblast growth factor receptor 2", "lang": "EN" }, { "name": "成纤维细胞生长因子受体-2", "lang": "CN" } ], [ ...	[ [ { "name": "FGFR2 fusion or rearranged Cholangiocarcinoma", "lang": "EN" }, { "name": "FGFR2融合或重排的胆管癌", "lang": "CN" } ], [ { "name": "Intrahepatic Cholangiocarcinoma", "lang": "EN" }, { "name": "肝内胆管癌", "lang": "CN" } ], [ ...	[ "Small molecule drug" ]	Phase 1/2 Clinical	1,664,496,000,000	[ [ { "name": "Intrahepatic Cholangiocarcinoma", "lang": "EN" }, { "name": "肝内胆管癌", "lang": "CN" } ] ]	[ "United States", "European Union", "Japan", "Australia", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "富马酸安奈克替尼", "lang": "CN" }, { "name": "Unecritinib", "lang": "EN" } ]	[ { "name": "安奈克替尼", "lang": "CN" } ]	[ [ { "name": "Anaplastic lymphoma kinase", "lang": "EN" }, { "name": "间变性淋巴瘤激酶", "lang": "CN" } ], [ { "name": "Proto-oncogene tyrosine-protein kinase ROS", "lang": "EN" }, { "name": "原癌基因酪氨酸蛋白激酶ROS", "lang": "CN" } ], [ { ...	[ [ { "name": "Reactive oxygen species 1 positive non-small cell lung cancer", "lang": "EN" }, { "name": "ROS1阳性非小细胞肺癌", "lang": "CN" } ], [ { "name": "Advanced cancer", "lang": "EN" }, { "name": "晚期癌症", "lang": "CN" } ], [ { ...	[ "Small molecule drug" ]	Discontinued	1,713,916,800,000	[ [ { "name": "Reactive oxygen species 1 positive non-small cell lung cancer", "lang": "EN" }, { "name": "ROS1阳性非小细胞肺癌", "lang": "CN" } ] ]	[ "China" ]
[ { "name": "安立生坦", "lang": "CN" }, { "name": "Ambrisentan", "lang": "EN" }, { "name": "アンブリセンタン", "lang": "JP" } ]	[ { "name": "(2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid", "lang": "EN" }, { "name": "Ambrisentan (JAN/INN)", "lang": "EN" } ]	[ [ { "name": "Endothelin receptor type A", "lang": "EN" }, { "name": "内皮素A受体", "lang": "CN" } ] ]	[ [ { "name": "Pulmonary arterial hypertension associated with connective tissue disease", "lang": "EN" }, { "name": "与结缔组织病相关的肺动脉高压", "lang": "CN" } ], [ { "name": "Idiopathic pulmonary arterial hypertension", "lang": "EN" }, { "name": "特发性肺动脉...	[ "Small molecule drug" ]	Pending	1,181,865,600,000	[ [ { "name": "Pulmonary Arterial Hypertension", "lang": "EN" }, { "name": "肺动脉高压", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "A型肉毒毒素 (Biotecon)", "lang": "CN" }, { "name": "Incobotulinum toxinA (Biotecon)", "lang": "EN" }, { "name": "インコボツリヌストキシンA", "lang": "JP" } ]	[ { "name": "Botulinum toxin A", "lang": "EN" }, { "name": "Botulinum toxin A (Merz Pharma)", "lang": "EN" }, { "name": "Incobotulinum toxin A", "lang": "EN" }, { "name": "IncobotulinumtoxinA", "lang": "EN" }, { "name": "Zeomaine", "lang": "EN" }, { "nam...	[ [ { "name": "Synaptosomal-associated protein 25", "lang": "EN" }, { "name": "突触相关蛋白25", "lang": "CN" } ] ]	[ [ { "name": "cervical dystonia", "lang": "EN" }, { "name": "颈肌张力障碍", "lang": "CN" } ], [ { "name": "Crow's feet", "lang": "EN" }, { "name": "鱼尾纹", "lang": "CN" } ], [ { "name": "Forehead lines", "lang": "EN" ...	[ "Toxin" ]	Pending	1,193,184,000,000	[ [ { "name": "Sialorrhea", "lang": "EN" }, { "name": "流涎", "lang": "CN" } ], [ { "name": "Spasm", "lang": "EN" }, { "name": "痉挛", "lang": "CN" } ] ]	[ "United States", "China", "Japan", "United Kingdom", "Canada", "Australia", "Austria", "Belgium", "Bulgaria", "Cyprus", "Czechia", "Germany", "Denmark", "Estonia", "Spain", "Finland", "France", "Greece", "Croatia", "Hungary", "Ireland", "Iceland", "Italy", "Liechtenstei...
[ { "name": "布比卡因/美洛昔康", "lang": "CN" }, { "name": "Bupivacaine/Meloxicam", "lang": "EN" } ]	[ { "name": "Meloxicam/bupivacaine", "lang": "EN" }, { "name": "ZYNRELEF", "lang": "EN" } ]	[ [ { "name": "Cyclooxygenase-1", "lang": "EN" }, { "name": "环氧化酶-1", "lang": "CN" } ], [ { "name": "Cyclooxygenase-2", "lang": "EN" }, { "name": "环氧化酶-2", "lang": "CN" } ], [ { "name": "Sodium voltage-gated channel alph...	[ [ { "name": "Pain, Postoperative", "lang": "EN" }, { "name": "术后疼痛", "lang": "CN" } ], [ { "name": "Analgesia", "lang": "EN" }, { "name": "镇痛", "lang": "CN" } ], [ { "name": "Bunion", "lang": "EN" }, { ...	[ "Small molecule drug" ]	Pending	1,600,905,600,000	[ [ { "name": "Pain, Postoperative", "lang": "EN" }, { "name": "术后疼痛", "lang": "CN" } ] ]	[ "United States", "Canada" ]
[ { "name": "盐酸胍法辛", "lang": "CN" }, { "name": "Guanfacine hydrochloride", "lang": "EN" }, { "name": "グアンファシン塩酸塩", "lang": "JP" } ]	[ { "name": "Connexyn", "lang": "EN" }, { "name": "Guanfacine XR", "lang": "EN" }, { "name": "Guanfacine hydrochloride (JAN/USP)", "lang": "EN" }, { "name": "Intuniv XR", "lang": "EN" }, { "name": "guanfacine", "lang": "EN" } ]	[ [ { "name": "Adrenergic receptors", "lang": "EN" }, { "name": "肾上腺素能受体家族", "lang": "CN" } ] ]	[ [ { "name": "Attention Deficit Disorder With Hyperactivity", "lang": "EN" }, { "name": "注意缺陷障碍伴多动", "lang": "CN" } ], [ { "name": "Anxiety, Separation", "lang": "EN" }, { "name": "分离性焦虑", "lang": "CN" } ], [ { "name": ...	[ "Small molecule drug" ]	Discontinued	530,755,200,000	[ [ { "name": "Hypertension", "lang": "EN" }, { "name": "高血压", "lang": "CN" } ] ]	[ "United States", "European Union", "Japan", "Australia", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "盐酸头孢替安酯", "lang": "CN" }, { "name": "Cefotiam hexetil hydrochloride", "lang": "EN" } ]	[ { "name": "Cefotiam hexetil hydrochloride (JP17)", "lang": "EN" } ]	[ [ { "name": "Alpha-2a adrenergic receptor", "lang": "EN" }, { "name": "肾上腺素能受体α-2a", "lang": "CN" } ] ]	[ [ { "name": "Abscess", "lang": "EN" }, { "name": "脓肿", "lang": "CN" } ], [ { "name": "Burn infections", "lang": "EN" }, { "name": "烧伤感染", "lang": "CN" } ], [ { "name": "Cystitis", "lang": "EN" }, { ...	[ "Small molecule drug" ]	Pending	631,152,000,000	[ [ { "name": "Abscess", "lang": "EN" }, { "name": "脓肿", "lang": "CN" } ], [ { "name": "Burn infections", "lang": "EN" }, { "name": "烧伤感染", "lang": "CN" } ], [ { "name": "Cystitis", "lang": "EN" }, { ...	[ "Japan" ]
[ { "name": "那昔妥单抗", "lang": "CN" }, { "name": "Naxitamab", "lang": "EN" } ]	[ { "name": "Anti-Gd2 igg3 monoclonal antibody 3F8 humanized", "lang": "EN" }, { "name": "Anti-Gd2 monoclonal antibody 3F8 humanized", "lang": "EN" }, { "name": "Humanised 3F8", "lang": "EN" }, { "name": "Humanised IgG1 monoclonal GD2 antibody", "lang": "EN" }, { "n...	[ [ { "name": "Disialoganglioside GD2", "lang": "EN" }, { "name": "唾液神经节苷脂GD2", "lang": "CN" } ] ]	[ [ { "name": "High Risk Neuroblastoma", "lang": "EN" }, { "name": "高风险神经母细胞瘤", "lang": "CN" } ], [ { "name": "Refractory Neuroblastoma", "lang": "EN" }, { "name": "难治性神经母细胞瘤", "lang": "CN" } ], [ { "name": "Ganglioneuro...	[ "Monoclonal antibody" ]	Phase 2 Clinical	1,606,262,400,000	[ [ { "name": "High Risk Neuroblastoma", "lang": "EN" }, { "name": "高风险神经母细胞瘤", "lang": "CN" } ] ]	[ "United States", "China", "Brazil", "Israel" ]
[ { "name": "奥布替尼", "lang": "CN" }, { "name": "Orelabrutinib", "lang": "EN" } ]	[ { "name": "Obrutinib", "lang": "EN" }, { "name": "abutinib", "lang": "EN" } ]	[ [ { "name": "Tyrosine-protein kinase BTK", "lang": "EN" }, { "name": "酪氨酸蛋白激酶BTK", "lang": "CN" } ] ]	[ [ { "name": "Marginal zone lymphoma recurrent", "lang": "EN" }, { "name": "复发性边缘区淋巴瘤", "lang": "CN" } ], [ { "name": "Refractory Marginal Zone Lymphoma", "lang": "EN" }, { "name": "难治性边缘区淋巴瘤", "lang": "CN" } ], [ { "na...	[ "Small molecule drug" ]	Approved	1,608,854,400,000	[ [ { "name": "Chronic Lymphocytic Leukemia", "lang": "EN" }, { "name": "慢性淋巴细胞白血病", "lang": "CN" } ], [ { "name": "Mantle-Cell Lymphoma", "lang": "EN" }, { "name": "套细胞淋巴瘤", "lang": "CN" } ], [ { "name": "Small Lymphocy...	[ "China", "Singapore" ]
[ { "name": "枸橼酸莫沙必利", "lang": "CN" }, { "name": "Mosapride Citrate Hydrate", "lang": "EN" }, { "name": "モサプリドクエン酸塩水和物", "lang": "JP" } ]	[ { "name": "Mosapride Citrate", "lang": "EN" }, { "name": "Mosapride citrate dihydrate", "lang": "EN" }, { "name": "Mosapride citrate hydrate (JP17)", "lang": "EN" } ]	[ [ { "name": "Serotonin 4 (5-HT4) receptor", "lang": "EN" }, { "name": "5-羟色胺受体4", "lang": "CN" } ] ]	[ [ { "name": "Gastritis", "lang": "EN" }, { "name": "胃炎", "lang": "CN" } ], [ { "name": "Urinary Calculi", "lang": "EN" }, { "name": "泌尿结石", "lang": "CN" } ], [ { "name": "Chronic gastritis", "lang": "EN" }, ...	[ "Small molecule drug" ]	Phase 2 Clinical	899,164,800,000	[ [ { "name": "Chronic gastritis", "lang": "EN" }, { "name": "慢性胃炎", "lang": "CN" } ] ]	[ "China", "Japan" ]
[ { "name": "Vandefitemcel", "lang": "EN" }, { "name": "バンデフィテムセル", "lang": "JP" } ]	[ { "name": "Modified bone marrow derived mesenchymal stem cells - SanBio", "lang": "EN" } ]	[ [ { "name": "Nerve growth factor", "lang": "EN" }, { "name": "神经生长因子", "lang": "CN" } ] ]	[ [ { "name": "Brain Injuries, Traumatic", "lang": "EN" }, { "name": "创伤性脑损伤", "lang": "CN" } ], [ { "name": "Hemorrhagic stroke", "lang": "EN" }, { "name": "出血性卒中", "lang": "CN" } ], [ { "name": "Ischemic stroke", ...	[ "Mesenchymal stem cell therapy" ]	Preclinical	1,722,384,000,000	[ [ { "name": "Brain Injuries, Traumatic", "lang": "EN" }, { "name": "创伤性脑损伤", "lang": "CN" } ] ]	[ "Japan" ]
[ { "name": "奥贝胆酸", "lang": "CN" }, { "name": "Obeticholic acid", "lang": "EN" } ]	[ { "name": "(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxycholan-24-oic acid", "lang": "EN" }, { "name": "6-Ethyl-CDCA", "lang": "EN" }, { "name": "6-ethyl-chenodeoxycholic-acid", "lang": "EN" }, { "name": "6-ethylchenodeoxycholic acid", "lang": "EN" }, { "name": "6alpha-Ethy...	[ [ { "name": "Bile acid receptor FXR", "lang": "EN" }, { "name": "胆汁酸受体FXR", "lang": "CN" } ] ]	[ [ { "name": "Primary Biliary Cholangitis", "lang": "EN" }, { "name": "原发性胆汁性胆管炎", "lang": "CN" } ], [ { "name": "Fibrosis, Liver", "lang": "EN" }, { "name": "肝纤维化", "lang": "CN" } ], [ { "name": "Biliary Atresia", ...	[ "Small molecule drug" ]	NDA/BLA	1,464,307,200,000	[ [ { "name": "Primary Biliary Cholangitis", "lang": "EN" }, { "name": "原发性胆汁性胆管炎", "lang": "CN" } ] ]	[ "Australia" ]
[ { "name": "司来帕格", "lang": "CN" }, { "name": "Selexipag", "lang": "EN" }, { "name": "セレキシパグ", "lang": "JP" } ]	[ { "name": "Selexipag (JAN/USAN/INN)", "lang": "EN" }, { "name": "赛乐西帕", "lang": "CN" } ]	[ [ { "name": "Prostanoid IP receptor", "lang": "EN" }, { "name": "前列腺素IP受体", "lang": "CN" } ] ]	[ [ { "name": "Chronic thromboembolic pulmonary hypertension", "lang": "EN" }, { "name": "慢性血栓栓塞性肺动脉高压", "lang": "CN" } ], [ { "name": "Pulmonary Arterial Hypertension", "lang": "EN" }, { "name": "肺动脉高压", "lang": "CN" } ], [ {...	[ "Small molecule drug" ]	Pending	1,450,656,000,000	[ [ { "name": "Pulmonary Arterial Hypertension", "lang": "EN" }, { "name": "肺动脉高压", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Canada", "Australia", "Switzerland", "Iceland", "South Korea", "Liechtenstein", "Norway" ]
[ { "name": "醋酸阿比特龙", "lang": "CN" }, { "name": "Abiraterone acetate", "lang": "EN" }, { "name": "アビラテロン酢酸エステル", "lang": "JP" } ]	[ { "name": "(3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol", "lang": "EN" }, { "name": "17-(3-Pyridyl)androsta-5,16-dien-3beta-ol", "lang": "EN" }, { "name": "Abiraterone acetate (JAN/USP)", "lang": "EN" }, { "name": "abiraterone", "lang": "EN" } ]	[ [ { "name": "Steroid 17-alpha-hydroxylase", "lang": "EN" }, { "name": "类固醇17-α-羟化酶", "lang": "CN" } ] ]	[ [ { "name": "Metastatic Prostate Carcinoma", "lang": "EN" }, { "name": "转移性前列腺癌", "lang": "CN" } ], [ { "name": "Prostate Neuroendocrine Carcinoma", "lang": "EN" }, { "name": "神经内分泌前列腺癌", "lang": "CN" } ], [ { "name": ...	[ "Small molecule drug" ]	Pending	1,303,948,800,000	[ [ { "name": "Metastatic castration-resistant prostate cancer", "lang": "EN" }, { "name": "转移性去势抵抗性前列腺癌", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Australia", "Brazil", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "西罗莫司(白蛋白结合型)", "lang": "CN" }, { "name": "Sirolimus Albumin-Bound", "lang": "EN" } ]	[ { "name": "Nab-Rapamycin", "lang": "EN" }, { "name": "Nab-sirolimus", "lang": "EN" }, { "name": "Nab-西罗莫司", "lang": "CN" }, { "name": "SRL-HSA", "lang": "EN" }, { "name": "Sirolimus Albumin-Bound Nanoparticles", "lang": "EN" }, { "name": "TARZIFYX", ...	[ [ { "name": "Methylmalonyl-CoA Mutase", "lang": "EN" }, { "name": "甲基丙二酰辅酶A变位酶", "lang": "CN" } ], [ { "name": "Serine/threonine-protein kinase mTOR", "lang": "EN" }, { "name": "丝氨酸/苏氨酸蛋白激酶mTOR", "lang": "CN" } ] ]	[ [ { "name": "Perivascular epithelioid cell tumour", "lang": "EN" }, { "name": "血管周围上皮样细胞肿瘤", "lang": "CN" } ], [ { "name": "Hormone receptor positive HER2 negative breast cancer", "lang": "EN" }, { "name": "HR阳性/HER2阴性乳腺癌", "lang": "CN"...	[ "Non-degrading molecular glue" ]	Pending	1,637,539,200,000	[ [ { "name": "Perivascular epithelioid cell tumour", "lang": "EN" }, { "name": "血管周围上皮样细胞肿瘤", "lang": "CN" } ] ]	[ "United States" ]
[ { "name": "信迪利单抗", "lang": "CN" }, { "name": "Sintilimab", "lang": "EN" } ]	[ { "name": "Sintilimab injection", "lang": "EN" }, { "name": "Tyvyt", "lang": "EN" } ]	[ [ { "name": "Programmed cell death protein 1", "lang": "EN" }, { "name": "细胞程序性死亡-1", "lang": "CN" } ] ]	[ [ { "name": "Mismatch repair-deficient Colonic Cancer", "lang": "EN" }, { "name": "错配修复缺陷或微高卫星不稳定性结肠癌", "lang": "CN" } ], [ { "name": "Advanced Endometrial Carcinoma", "lang": "EN" }, { "name": "晚期子宫内膜癌", "lang": "CN" } ], [ ...	[ "Monoclonal antibody" ]	Pending	1,545,609,600,000	[ [ { "name": "Hodgkin's Lymphoma", "lang": "EN" }, { "name": "霍奇金淋巴瘤", "lang": "CN" } ] ]	[ "China", "Macao" ]
[ { "name": "可利霉素", "lang": "CN" }, { "name": "Carrimycin", "lang": "EN" } ]	[ { "name": "Biotechmycin", "lang": "EN" }, { "name": "Biotechspiramycin", "lang": "EN" }, { "name": "Levocarrimycin", "lang": "EN" }, { "name": "bitespiramycin", "lang": "EN" }, { "name": "isovalerylspiramycin", "lang": "EN" }, { "name": "isovalerylspir...	[ [ { "name": "50S ribosomal subunit", "lang": "EN" }, { "name": "50S核糖体亚基", "lang": "CN" } ] ]	[ [ { "name": "Bacterial Infections", "lang": "EN" }, { "name": "细菌感染", "lang": "CN" } ], [ { "name": "Bronchiectasis", "lang": "EN" }, { "name": "支气管扩张", "lang": "CN" } ], [ { "name": "Pseudomonas aeruginosa infection",...	[ "Small molecule drug" ]	Discontinued	1,561,334,400,000	[ [ { "name": "Bacterial Infections", "lang": "EN" }, { "name": "细菌感染", "lang": "CN" } ] ]	[ "China" ]
[ { "name": "布西珠单抗", "lang": "CN" }, { "name": "Brolucizumab-dbll", "lang": "EN" }, { "name": "ブロルシズマブ（遺伝子組換え）", "lang": "JP" } ]	[ { "name": "Brolucizumab (Genetical Recombination)", "lang": "EN" }, { "name": "brolucizumab", "lang": "EN" }, { "name": "布罗鲁珠单抗", "lang": "CN" }, { "name": "溴珠单抗", "lang": "CN" }, { "name": "溴鲁西单抗", "lang": "CN" } ]	[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]	[ [ { "name": "Proliferative retinopathy with diabetes mellitus", "lang": "EN" }, { "name": "伴有糖尿病的增殖性视网膜病变", "lang": "CN" } ], [ { "name": "Choroidal Neovascularization", "lang": "EN" }, { "name": "脉络膜新生血管", "lang": "CN" } ], [ ...	[ "Single-chain FV antibody fragment" ]	Approved	1,570,406,400,000	[ [ { "name": "Wet age-related macular degeneration", "lang": "EN" }, { "name": "湿性年龄相关性黄斑变性", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Canada", "Australia", "Iceland", "South Korea", "Liechtenstein", "Norway" ]
[ { "name": "盐酸羟甲唑啉/马来酸氯苯那敏/甘草酸二钾", "lang": "CN" }, { "name": "Oxymetazoline Hydrochloride/Chlorpheniramine Maleate/Glycyrrhizinate dipotassium", "lang": "EN" } ]	[ { "name": "盐酸羟甲唑啉/马来酸扑尔敏/甘草酸二钾", "lang": "CN" } ]	[ [ { "name": "Corticosteroid 11-beta-dehydrogenase isozyme 1", "lang": "EN" }, { "name": "11β-羟基类固醇脱氢酶-1", "lang": "CN" } ], [ { "name": "Histamine H1 receptor", "lang": "EN" }, { "name": "组胺H1受体", "lang": "CN" } ], [ { ...	[ [ { "name": "Common Cold", "lang": "EN" }, { "name": "普通感冒", "lang": "CN" } ], [ { "name": "Rhinitis, Allergic", "lang": "EN" }, { "name": "过敏性鼻炎", "lang": "CN" } ], [ { "name": "Sinusitis", "lang": "EN" }, ...	[ "Small molecule drug" ]	Approved	1,722,988,800,000	[ [ { "name": "Common Cold", "lang": "EN" }, { "name": "普通感冒", "lang": "CN" } ], [ { "name": "Rhinitis, Allergic", "lang": "EN" }, { "name": "过敏性鼻炎", "lang": "CN" } ], [ { "name": "Sinusitis", "lang": "EN" }, ...	[ "South Korea" ]
[ { "name": "托品卡胺/利多卡因/去氧肾上腺素", "lang": "CN" }, { "name": "Tropicamide/Lidocaine/Phenylephrine", "lang": "EN" } ]	[ { "name": "Fydrane", "lang": "EN" }, { "name": "Lidocaine/phenylephrine/tropicamide", "lang": "EN" }, { "name": "Mydane", "lang": "EN" }, { "name": "Mydrane", "lang": "EN" }, { "name": "Mydricaine", "lang": "EN" } ]	[ [ { "name": "Sodium voltage-gated channel alpha subunits", "lang": "EN" }, { "name": "电压门控钠通道α亚基家族", "lang": "CN" } ], [ { "name": "Muscarinic acetylcholine receptor", "lang": "EN" }, { "name": "毒蕈碱型乙酰胆碱受体家族", "lang": "CN" } ] ]	[ [ { "name": "Miosis", "lang": "EN" }, { "name": "瞳孔缩小", "lang": "CN" } ], [ { "name": "Anesthesia", "lang": "EN" }, { "name": "麻醉", "lang": "CN" } ], [ { "name": "Cataract", "lang": "EN" }, { "name"...	[ "Small molecule drug" ]	Pending	1,466,035,200,000	[ [ { "name": "Anesthesia", "lang": "EN" }, { "name": "麻醉", "lang": "CN" } ] ]	[ "United Kingdom" ]
[ { "name": "甲磺酸仑伐替尼", "lang": "CN" }, { "name": "Lenvatinib mesylate", "lang": "EN" }, { "name": "レンバチニブメシル酸塩", "lang": "JP" } ]	[ { "name": "Lenvatinib mesilate (JAN)", "lang": "EN" }, { "name": "Lenvatinib mesylate (USAN)", "lang": "EN" }, { "name": "lenvatinib", "lang": "EN" }, { "name": "lenvatinib mesilate", "lang": "EN" }, { "name": "甲磺酸乐伐替尼", "lang": "CN" } ]	[ [ { "name": "Fibroblast growth factor receptor 1", "lang": "EN" }, { "name": "成纤维细胞生长因子受体-1", "lang": "CN" } ], [ { "name": "Fibroblast growth factor receptor 2", "lang": "EN" }, { "name": "成纤维细胞生长因子受体-2", "lang": "CN" } ], [ ...	[ [ { "name": "Advanced Endometrial Carcinoma", "lang": "EN" }, { "name": "晚期子宫内膜癌", "lang": "CN" } ], [ { "name": "Recurrent Endometrial Cancer", "lang": "EN" }, { "name": "复发性子宫内膜癌", "lang": "CN" } ], [ { "name": "Thym...	[ "Small molecule drug" ]	Pending	1,423,785,600,000	[ [ { "name": "Thyroid Cancer", "lang": "EN" }, { "name": "甲状腺癌", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "South Korea", "Liechtenstein", "Norway", "Taiwan Province" ]
[ { "name": "盐酸替利洛尔", "lang": "CN" }, { "name": "Tilisolol Hydrochloride", "lang": "EN" } ]	[ { "name": "Daim", "lang": "EN" }, { "name": "Tilisolol", "lang": "EN" }, { "name": "Tilisolol hydrochloride (JAN)", "lang": "EN" } ]	[ [ { "name": "Beta adrenergic receptors", "lang": "EN" }, { "name": "β-肾上腺素能受体家族", "lang": "CN" } ] ]	[ [ { "name": "Hypertension", "lang": "EN" }, { "name": "高血压", "lang": "CN" } ], [ { "name": "Angina Pectoris", "lang": "EN" }, { "name": "心绞痛", "lang": "CN" } ], [ { "name": "Arrhythmias, Cardiac", "lang": "EN" ...	[ "Small molecule drug" ]	Discontinued	800,064,000,000	[ [ { "name": "Angina Pectoris", "lang": "EN" }, { "name": "心绞痛", "lang": "CN" } ] ]	[ "Japan" ]
[ { "name": "乙酰半胱氨酸", "lang": "CN" }, { "name": "Acetylcysteine", "lang": "EN" }, { "name": "アセチルシステイン", "lang": "JP" } ]	[ { "name": "(2R)-2-acetylamino-3-sulfanylpropanoic acid", "lang": "EN" }, { "name": "(R)-2-acetylamino-3-mercaptopropanoic acid", "lang": "EN" }, { "name": "(R)-mercapturic acid", "lang": "EN" }, { "name": "Acetylcysteine (JP17/USP/INN)", "lang": "EN" }, { "name": ...	[ [ { "name": "Free radicals", "lang": "EN" }, { "name": "自由基", "lang": "CN" } ] ]	[ [ { "name": "Bronchiectasis", "lang": "EN" }, { "name": "支气管扩张", "lang": "CN" } ], [ { "name": "Bronchitis", "lang": "EN" }, { "name": "支气管炎", "lang": "CN" } ], [ { "name": "Pulmonary Emphysema", "lang": "EN" ...	[ "Small molecule drug" ]	Discontinued	-198,806,400,000	[ [ { "name": "Chemical and Drug Induced Liver Injury", "lang": "EN" }, { "name": "药物性肝损伤", "lang": "CN" } ], [ { "name": "Liver Injury", "lang": "EN" }, { "name": "肝损伤", "lang": "CN" } ] ]	[ "United States", "China", "Japan", "Australia" ]
[ { "name": "布林西多福韦", "lang": "CN" }, { "name": "Brincidofovir", "lang": "EN" } ]	[ { "name": "BCV", "lang": "EN" }, { "name": "Brincidofovir (USAN)", "lang": "EN" }, { "name": "Cidofovir hexadecyloxypropyl ester", "lang": "EN" }, { "name": "HDP-CDV", "lang": "EN" }, { "name": "HDP-cidofovir", "lang": "EN" }, { "name": "Hexadecyl-oxyp...	[ [ { "name": "Human herpesvirus 1 DNA polymerase", "lang": "EN" }, { "name": "人单纯疱疹病毒1型DNA聚合酶", "lang": "CN" } ], [ { "name": "Human herpesvirus 5 DNA polymerase", "lang": "EN" }, { "name": "人单纯疱疹病毒5型DNA聚合酶", "lang": "CN" } ] ]	[ [ { "name": "Smallpox", "lang": "EN" }, { "name": "天花", "lang": "CN" } ], [ { "name": "Adenovirus Infections, Human", "lang": "EN" }, { "name": "腺病毒感染", "lang": "CN" } ], [ { "name": "Leukoencephalopathy, Progressive M...	[ "Small molecule drug" ]	Discontinued	1,622,764,800,000	[ [ { "name": "Smallpox", "lang": "EN" }, { "name": "天花", "lang": "CN" } ] ]	[ "United States", "Canada" ]
[ { "name": "康柏西普", "lang": "CN" }, { "name": "Conbercept", "lang": "EN" } ]	[ { "name": "Conbercept Ophthalmic", "lang": "EN" }, { "name": "Lumitin", "lang": "EN" }, { "name": "Recombinant human VEGF receptor-Fc fusion protein", "lang": "EN" }, { "name": "重组人血管内皮生长因子受体-抗体融合蛋白（成都市康弘生物）", "lang": "CN" } ]	[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]	[ [ { "name": "Retinal vein occlusion-related macular edema", "lang": "EN" }, { "name": "视网膜静脉阻塞相关黄斑水肿", "lang": "CN" } ], [ { "name": "Diabetic macular oedema", "lang": "EN" }, { "name": "糖尿病性黄斑水肿", "lang": "CN" } ], [ { ...	[ "Fc fusion protein" ]	Pending	1,385,510,400,000	[ [ { "name": "Wet age-related macular degeneration", "lang": "EN" }, { "name": "湿性年龄相关性黄斑变性", "lang": "CN" } ] ]	[ "China" ]
[ { "name": "艾司奥美拉唑镁/碳酸氢钠", "lang": "CN" }, { "name": "Esomeprazole Magnesium/Sodium Bicarbonate", "lang": "EN" } ]	[ { "name": "埃索美拉唑镁/碳酸氢钠", "lang": "CN" }, { "name": "奥美拉唑镁碳酸氢钠", "lang": "CN" } ]	[ [ { "name": "Proton pump", "lang": "EN" }, { "name": "质子泵", "lang": "CN" } ] ]	[ [ { "name": "Hyperchlorhydria", "lang": "EN" }, { "name": "胃酸过多", "lang": "CN" } ], [ { "name": "Duodenal Ulcer", "lang": "EN" }, { "name": "十二指肠溃疡", "lang": "CN" } ], [ { "name": "Erosive esophagitis", "lang": "...	[ "Small molecule drug" ]	IND Approval	1,525,046,400,000	[ [ { "name": "Gastroesophageal Reflux", "lang": "EN" }, { "name": "胃食管反流", "lang": "CN" } ] ]	[ "China", "South Korea" ]
[ { "name": "甲酪氨酸", "lang": "CN" }, { "name": "Metyrosine", "lang": "EN" }, { "name": "メチロシン", "lang": "JP" } ]	[ { "name": "(-)-alpha-Methyl-L-tyrosine", "lang": "EN" }, { "name": "(-)-α-methyl-L-tyrosine", "lang": "EN" }, { "name": "(S)-alpha-Methyltyrosine", "lang": "EN" }, { "name": "(–)-α-methyl-L-tyrosine", "lang": "EN" }, { "name": "AMPT", "lang": "EN" }, { ...	[ [ { "name": "Tyrosine 3-hydroxylase", "lang": "EN" }, { "name": "酪氨酸-3-羟化酶", "lang": "CN" } ] ]	[ [ { "name": "Pheochromocytoma", "lang": "EN" }, { "name": "嗜铬细胞瘤", "lang": "CN" } ], [ { "name": "Bipolar Disorder", "lang": "EN" }, { "name": "躁郁症", "lang": "CN" } ], [ { "name": "DiGeorge Syndrome", "lang": "EN...	[ "Small molecule drug" ]	Discontinued	307,756,800,000	[ [ { "name": "Pheochromocytoma", "lang": "EN" }, { "name": "嗜铬细胞瘤", "lang": "CN" } ] ]	[ "United States", "Japan" ]
[ { "name": "马来酸氯苯那敏/氢溴酸东莨菪碱水合物/无水咖啡因/烟酰胺/盐酸吡哆醇", "lang": "CN" }, { "name": "Chlorpheniramine Maleate/Scopolamine Hydrobromide Hydrate/Anhydrous Caffeine/Nicotinamide/Pyridoxine Hydrochloride", "lang": "EN" } ]	null	[ [ { "name": "Adenosine A2a receptor", "lang": "EN" }, { "name": "腺苷A2a受体", "lang": "CN" } ], [ { "name": "Poly (ADP-Ribose) polymerase 1", "lang": "EN" }, { "name": "聚腺苷二磷酸核糖聚合酶1", "lang": "CN" } ], [ { "name": "Histam...	[ [ { "name": "Motion Sickness", "lang": "EN" }, { "name": "晕动病", "lang": "CN" } ] ]	[ "Small molecule drug" ]	Approved	1,753,660,800,000	[ [ { "name": "Motion Sickness", "lang": "EN" }, { "name": "晕动病", "lang": "CN" } ] ]	[ "South Korea" ]
[ { "name": "德曲妥珠单抗", "lang": "CN" }, { "name": "Fam-trastuzumab deruxtecan-NXKI", "lang": "EN" }, { "name": "トラスツズマブデルクステカン（遺伝子組換え）", "lang": "JP" } ]	[ { "name": "Fam-trastuzumab deruxtecan", "lang": "EN" }, { "name": "T-DXd", "lang": "EN" }, { "name": "Trastuzumab Deruxtecan (Genetical Recombination)", "lang": "EN" }, { "name": "Trastuzumab deruxtecan", "lang": "EN" }, { "name": "德喜曲妥珠单抗", "lang": "CN" }, ...	[ [ { "name": "Receptor tyrosine-protein kinase erbB-2", "lang": "EN" }, { "name": "受体蛋白酪氨酸激酶 erbB-2", "lang": "CN" } ], [ { "name": "DNA topoisomerase I", "lang": "EN" }, { "name": "DNA拓扑异构酶I", "lang": "CN" } ] ]	[ [ { "name": "Stomach Cancer", "lang": "EN" }, { "name": "胃癌", "lang": "CN" } ], [ { "name": "HER2 Positive Solid Tumors", "lang": "EN" }, { "name": "HER2阳性实体瘤", "lang": "CN" } ], [ { "name": "HR-positive/HER2-low Breas...	[ "Antibody drug conjugate (ADC)" ]	Approved	1,576,800,000,000	[ [ { "name": "HER2 Positive Breast Cancer", "lang": "EN" }, { "name": "HER2阳性乳腺癌", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "United Kingdom", "Canada", "Australia", "India", "Israel", "Iceland", "South Korea", "Liechtenstein", "Norway" ]
[ { "name": "艾普拉唑钠", "lang": "CN" }, { "name": "Sodium ilaprazole", "lang": "EN" } ]	null	[ [ { "name": "Proton pump", "lang": "EN" }, { "name": "质子泵", "lang": "CN" } ] ]	[ [ { "name": "Peptic Ulcer Hemorrhage", "lang": "EN" }, { "name": "消化性溃疡出血", "lang": "CN" } ], [ { "name": "Hemorrhage", "lang": "EN" }, { "name": "出血", "lang": "CN" } ], [ { "name": "Peptic Ulcer", "lang": "EN" ...	[ "Small molecule drug" ]	Phase 3 Clinical	1,514,419,200,000	[ [ { "name": "Peptic Ulcer Hemorrhage", "lang": "EN" }, { "name": "消化性溃疡出血", "lang": "CN" } ] ]	[ "China", "Indonesia" ]
[ { "name": "贝伐珠单抗生物类似药（Curateq）", "lang": "CN" }, { "name": "Bevacizumab Biosimilar (CuraTeQ)", "lang": "EN" } ]	[ { "name": "Bevacizumab Biosimilar (Curateq Biologics Pvt Ltd.)", "lang": "EN" }, { "name": "贝伐珠单抗生物类似药（Curateq Biologics Pvt Ltd.）", "lang": "CN" } ]	[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]	[ [ { "name": "Advanced Renal Cell Carcinoma", "lang": "EN" }, { "name": "晚期肾细胞癌", "lang": "CN" } ], [ { "name": "EGFR positive Non-squamous non-small cell lung cancer", "lang": "EN" }, { "name": "EGFR阳性非鳞状非小细胞肺癌", "lang": "CN" } ],...	[ "Biosimilar", "Monoclonal antibody" ]	Approved	1,734,652,800,000	[ [ { "name": "Advanced Renal Cell Carcinoma", "lang": "EN" }, { "name": "晚期肾细胞癌", "lang": "CN" } ], [ { "name": "EGFR positive Non-squamous non-small cell lung cancer", "lang": "EN" }, { "name": "EGFR阳性非鳞状非小细胞肺癌", "lang": "CN" } ],...	[ "United Kingdom" ]
[ { "name": "福莫司汀", "lang": "CN" }, { "name": "Fotemustine", "lang": "EN" } ]	[ { "name": "(+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate", "lang": "EN" }, { "name": "Diethyl-1-(3-(2-chloroethyl)-3-nitrosoureido)ethylphosphonate", "lang": "EN" }, { "name": "Fotemustine (INN/BAN)", "lang": "EN" }, { "name": "Muforan", "lang": "EN...	[ [ { "name": "DNA", "lang": "EN" }, { "name": "DNA", "lang": "CN" } ] ]	[ [ { "name": "Brain Cancer", "lang": "EN" }, { "name": "脑癌", "lang": "CN" } ], [ { "name": "Melanoma", "lang": "EN" }, { "name": "黑色素瘤", "lang": "CN" } ], [ { "name": "metastatic non-small cell lung cancer", "lang...	[ "Small molecule drug" ]	Pending	625,881,600,000	[ [ { "name": "Brain Cancer", "lang": "EN" }, { "name": "脑癌", "lang": "CN" } ], [ { "name": "Melanoma", "lang": "EN" }, { "name": "黑色素瘤", "lang": "CN" } ] ]	[ "China", "France" ]
[ { "name": "氯替泼诺妥布霉素", "lang": "CN" }, { "name": "Loteprednol Etabonate/Tobramycin", "lang": "EN" } ]	[ { "name": "LE-T", "lang": "EN" }, { "name": "LE-Tobramycin", "lang": "EN" }, { "name": "Loteprednol Etabonate and Tobramycin", "lang": "EN" }, { "name": "Tobramycin/loteprednol etabonate", "lang": "EN" }, { "name": "Zylet", "lang": "EN" }, { "name": "氯...	[ [ { "name": "30S ribosomal subunit", "lang": "EN" }, { "name": "30S核糖体亚基", "lang": "CN" } ], [ { "name": "Glucocorticoid receptor", "lang": "EN" }, { "name": "糖皮质激素受体", "lang": "CN" } ], [ { "name": "Cytosolic phosphol...	[ [ { "name": "Ocular inflammation", "lang": "EN" }, { "name": "眼部炎症", "lang": "CN" } ], [ { "name": "Blepharitis", "lang": "EN" }, { "name": "睑缘炎", "lang": "CN" } ], [ { "name": "Blepharokeratoconjunctivitis", "la...	[ "Small molecule drug" ]	Pending	1,102,982,400,000	[ [ { "name": "Ocular inflammation", "lang": "EN" }, { "name": "眼部炎症", "lang": "CN" } ] ]	[ "United States", "China" ]
[ { "name": "甲基卡泰司特", "lang": "CN" }, { "name": "Carotegrast methyl", "lang": "EN" }, { "name": "カロテグラストメチル", "lang": "JP" } ]	[ { "name": "Carotegrast", "lang": "EN" }, { "name": "Carotegrast methyl (JAN)", "lang": "EN" } ]	[ [ { "name": "Integrin alpha-4/beta-1", "lang": "EN" }, { "name": "整合素α-4/β-1复合体", "lang": "CN" } ], [ { "name": "Integrin alpha-4/beta-7", "lang": "EN" }, { "name": "整合素α-4/β-7复合体", "lang": "CN" } ] ]	[ [ { "name": "Colitis, Ulcerative", "lang": "EN" }, { "name": "溃疡性结肠炎", "lang": "CN" } ] ]	[ "Small molecule drug" ]	Approved	1,648,425,600,000	[ [ { "name": "Colitis, Ulcerative", "lang": "EN" }, { "name": "溃疡性结肠炎", "lang": "CN" } ] ]	[ "Japan" ]
[ { "name": "促皮质素", "lang": "CN" }, { "name": "Corticotropin", "lang": "EN" } ]	[ { "name": "ACTH", "lang": "EN" }, { "name": "Adrenocorticotrophin", "lang": "EN" }, { "name": "Adrenocorticotropic hormone", "lang": "EN" }, { "name": "CORTICOTROPIN-ZINC HYDROXIDE", "lang": "EN" }, { "name": "Corticotrophin", "lang": "EN" }, { "name":...	[ [ { "name": "Melanocortin receptor", "lang": "EN" }, { "name": "黑皮质素受体", "lang": "CN" } ] ]	[ [ { "name": "Choroiditis", "lang": "EN" }, { "name": "脉络膜炎", "lang": "CN" } ], [ { "name": "Iridocyclitis", "lang": "EN" }, { "name": "虹膜睫状体炎", "lang": "CN" } ], [ { "name": "Iritis", "lang": "EN" }, { ...	[ "Synthetic peptide" ]	Pending	-615,340,800,000	[ [ { "name": "Arthritis, Psoriatic", "lang": "EN" }, { "name": "银屑病关节炎", "lang": "CN" } ], [ { "name": "Dermatomyositis", "lang": "EN" }, { "name": "皮肌炎", "lang": "CN" } ], [ { "name": "Edema", "lang": "EN" },...	[ "United States" ]
[ { "name": "托珠单抗生物类似药（丽珠）", "lang": "CN" }, { "name": "Tocilizumab biosimilar (Livzon)", "lang": "EN" } ]	[ { "name": "重组人源化抗人IL-6R单克隆抗体", "lang": "CN" } ]	[ [ { "name": "Interleukin-6 receptor alpha subunit", "lang": "EN" }, { "name": "白细胞介素-6受体α亚基", "lang": "CN" } ] ]	[ [ { "name": "Rheumatoid Arthritis", "lang": "EN" }, { "name": "类风湿关节炎", "lang": "CN" } ] ]	[ "Biosimilar", "Monoclonal antibody" ]	Approved	1,674,000,000,000	[ [ { "name": "Rheumatoid Arthritis", "lang": "EN" }, { "name": "类风湿关节炎", "lang": "CN" } ] ]	[ "China" ]
[ { "name": "枸橼酸托瑞米芬", "lang": "CN" }, { "name": "Toremifene Citrate", "lang": "EN" }, { "name": "トレミフェンクエン酸塩", "lang": "JP" } ]	[ { "name": "Acapodene", "lang": "EN" }, { "name": "Toremifene citrate (JAN/USAN)", "lang": "EN" }, { "name": "toremifene", "lang": "EN" }, { "name": "托瑞米芬", "lang": "CN" } ]	[ [ { "name": "Estrogen receptors", "lang": "EN" }, { "name": "雌激素受体家族", "lang": "CN" } ] ]	[ [ { "name": "Estrogen receptor-negative breast cancer", "lang": "EN" }, { "name": "ER阴性乳腺癌", "lang": "CN" } ], [ { "name": "Metastatic breast cancer", "lang": "EN" }, { "name": "转移性乳腺癌", "lang": "CN" } ], [ { "name": "...	[ "Small molecule drug" ]	Preclinical	796,608,000,000	[ [ { "name": "Breast Cancer", "lang": "EN" }, { "name": "乳腺癌", "lang": "CN" } ] ]	[ "China", "European Union", "Japan", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "尼古丁", "lang": "CN" }, { "name": "Nicotine", "lang": "EN" } ]	[ { "name": "(S)-(−)-nicotine", "lang": "EN" }, { "name": "(S)-3-(1-methylpyrrolidin-2-yl)pyridine", "lang": "EN" }, { "name": "(S)-3-(N-methylpyrrolidin-2-yl)pyridine", "lang": "EN" }, { "name": "(S)-Nicotine", "lang": "EN" }, { "name": "(−)-nicotine", "lang": ...	[ [ { "name": "Muscle-type nicotinic acetylcholine receptor", "lang": "EN" }, { "name": "肌肉型烟碱乙酰胆碱受体复合体", "lang": "CN" } ] ]	[ [ { "name": "Smoking Cessation", "lang": "EN" }, { "name": "尼古丁成瘾", "lang": "CN" } ], [ { "name": "Tobacco Use Disorder", "lang": "EN" }, { "name": "烟草依赖", "lang": "CN" } ], [ { "name": "Nicotine Dependence", "la...	[ "Small molecule drug" ]	Early Phase 1	442,800,000,000	[ [ { "name": "Nicotine Dependence", "lang": "EN" }, { "name": "尼古丁依赖", "lang": "CN" } ] ]	[ "United States", "China", "Japan", "Australia", "South Korea" ]
[ { "name": "盐酸芬戈莫德", "lang": "CN" }, { "name": "Fingolimod Hydrochloride", "lang": "EN" }, { "name": "フィンゴリモド塩酸塩", "lang": "JP" } ]	[ { "name": "FINGOLIMOD", "lang": "EN" }, { "name": "Fingolimod hydrochloride (JAN/USAN)", "lang": "EN" }, { "name": "Gilenia", "lang": "EN" } ]	[ [ { "name": "Sphingosine 1-phosphate receptor Edg-1", "lang": "EN" }, { "name": "鞘氨醇-1-磷酸受体-Edg-1", "lang": "CN" } ], [ { "name": "Sphingosine 1-phosphate receptor Edg-3", "lang": "EN" }, { "name": "鞘氨醇-1-磷酸受体-Edg-3", "lang": "CN" }...	[ [ { "name": "Multiple Sclerosis, Relapsing-Remitting", "lang": "EN" }, { "name": "复发-缓解型多发性硬化", "lang": "CN" } ], [ { "name": "Multiple Sclerosis", "lang": "EN" }, { "name": "多发性硬化症", "lang": "CN" } ], [ { "name": "Mul...	[ "Small molecule drug" ]	Preclinical	1,285,027,200,000	[ [ { "name": "Multiple sclerosis relapse", "lang": "EN" }, { "name": "复发性多发性硬化", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "South Korea", "Liechtenstein", "Norway" ]
[ { "name": "利那洛肽", "lang": "CN" }, { "name": "Linaclotide", "lang": "EN" }, { "name": "リナクロチド", "lang": "JP" } ]	[ { "name": "Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr (disulfide bridge: 1-6; 2-10; 5-13)", "lang": "EN" }, { "name": "Linaclotide (JAN/USAN)", "lang": "EN" }, { "name": "Linaclotide acetate", "lang": "EN" } ]	[ [ { "name": "Heat-stable enterotoxin receptor", "lang": "EN" }, { "name": "热稳定肠毒素受体", "lang": "CN" } ], [ { "name": "Soluble guanylate cyclase", "lang": "EN" }, { "name": "可溶性鸟苷酸环化酶复合体", "lang": "CN" } ] ]	[ [ { "name": "Constipation - functional", "lang": "EN" }, { "name": "功能性便秘", "lang": "CN" } ], [ { "name": "Chronic constipation", "lang": "EN" }, { "name": "慢性便秘", "lang": "CN" } ], [ { "name": "Chronic idiopathic cons...	[ "Synthetic peptide", "Cyclic Peptide" ]	Pending	1,346,284,800,000	[ [ { "name": "Chronic idiopathic constipation", "lang": "EN" }, { "name": "慢性特发性便秘", "lang": "CN" } ], [ { "name": "Irritable bowel syndrome with constipation", "lang": "EN" }, { "name": "便秘型肠易激综合征", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "United Kingdom", "Canada", "Australia", "Switzerland", "Iceland", "Liechtenstein", "Mexico", "Norway" ]
[ { "name": "溴美喷酯", "lang": "CN" }, { "name": "Mepenzolate Bromide", "lang": "EN" }, { "name": "メペンゾラート臭化物", "lang": "JP" } ]	[ { "name": "Mepenzolate bromide (JP17/INN)", "lang": "EN" } ]	[ [ { "name": "Muscarinic acetylcholine receptor", "lang": "EN" }, { "name": "毒蕈碱型乙酰胆碱受体家族", "lang": "CN" } ] ]	[ [ { "name": "Irritable Bowel Syndrome", "lang": "EN" }, { "name": "肠易激综合征", "lang": "CN" } ], [ { "name": "Peptic Ulcer", "lang": "EN" }, { "name": "消化性溃疡", "lang": "CN" } ] ]	[ "Small molecule drug" ]	Withdrawn	-414,374,400,000	[ [ { "name": "Peptic Ulcer", "lang": "EN" }, { "name": "消化性溃疡", "lang": "CN" } ] ]	[ "Japan" ]
[ { "name": "尼卡利单抗", "lang": "CN" }, { "name": "Nipocalimab-aahu", "lang": "EN" }, { "name": "ニポカリマブ（遺伝子組換え）", "lang": "JP" } ]	[ { "name": "Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimer", "lang": "EN" }, { "name": "Nipocalimab (USAN)", "lang": "EN" }, { "name": "anti-FcRn monoclonal antibody(Momenta Pharmaceu...	[ [ { "name": "IgG receptor FcRn large subunit p51", "lang": "EN" }, { "name": "IgG受体FcRn大亚基p51", "lang": "CN" } ] ]	[ [ { "name": "Myasthenia Gravis", "lang": "EN" }, { "name": "重症肌无力", "lang": "CN" } ], [ { "name": "Warm autoimmune hemolytic anemia", "lang": "EN" }, { "name": "温热型自身免疫性溶血性贫血", "lang": "CN" } ], [ { "name": "Systemic L...	[ "Monoclonal antibody" ]	Phase 2/3 Clinical	1,745,884,800,000	[ [ { "name": "Myasthenia Gravis", "lang": "EN" }, { "name": "重症肌无力", "lang": "CN" } ] ]	[ "United States", "European Union", "Japan", "Canada", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "盐酸氮卓斯汀", "lang": "CN" }, { "name": "Azelastine Hydrochloride", "lang": "EN" }, { "name": "アゼラスチン塩酸塩", "lang": "JP" } ]	[ { "name": "4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone", "lang": "EN" }, { "name": "Afluon", "lang": "EN" }, { "name": "Allergodil", "lang": "EN" }, { "name": "Astepro", "lang": "EN" }, { "name": "Astepro Once-Daily", "lang": ...	[ [ { "name": "Histamine H1 receptor", "lang": "EN" }, { "name": "组胺H1受体", "lang": "CN" } ] ]	[ [ { "name": "Respiratory Tract Infections", "lang": "EN" }, { "name": "呼吸道感染", "lang": "CN" } ], [ { "name": "Rhinitis, Allergic, Perennial", "lang": "EN" }, { "name": "常年性变应性鼻炎", "lang": "CN" } ], [ { "name": "Rhiniti...	[ "Small molecule drug" ]	Withdrawn	515,203,200,000	[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ], [ { "name": "Rhinitis, Allergic", "lang": "EN" }, { "name": "过敏性鼻炎", "lang": "CN" } ] ]	[ "United States", "China", "Japan", "Australia" ]
[ { "name": "雷珠单抗生物类似药(Formycon AG)", "lang": "CN" }, { "name": "Ranibizumab biosimilar(Formycon AG)", "lang": "EN" } ]	[ { "name": "RANIBIZUMAB-EQRN", "lang": "EN" }, { "name": "Ranibizumab Biosimilar (Formycon AG)", "lang": "EN" }, { "name": "Ranibizumab-leyk", "lang": "EN" }, { "name": "雷珠单抗生物类似药（Formycon AG）", "lang": "CN" } ]	[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]	[ [ { "name": "Choroidal Neovascularization", "lang": "EN" }, { "name": "脉络膜新生血管", "lang": "CN" } ], [ { "name": "Diabetic macular oedema", "lang": "EN" }, { "name": "糖尿病性黄斑水肿", "lang": "CN" } ], [ { "name": "Diabetic Re...	[ "Fab fragment", "Biosimilar" ]	Approved	1,652,745,600,000	[ [ { "name": "Dystrophy, Macular", "lang": "EN" }, { "name": "黄斑变性", "lang": "CN" } ] ]	[ "United States", "United Kingdom" ]
[ { "name": "重酒石酸肾上腺素", "lang": "CN" }, { "name": "Epinephrine Bitartrate", "lang": "EN" } ]	[ { "name": "Epinephrine bitartrate (JAN/USP)", "lang": "EN" }, { "name": "酒石酸肾上腺素", "lang": "CN" } ]	[ [ { "name": "Adrenergic receptor alpha-1", "lang": "EN" }, { "name": "肾上腺素能受体α-1家族", "lang": "CN" } ], [ { "name": "Beta adrenergic receptors", "lang": "EN" }, { "name": "β-肾上腺素能受体家族", "lang": "CN" } ] ]	[ [ { "name": "Hypersensitivity", "lang": "EN" }, { "name": "超敏反应", "lang": "CN" } ], [ { "name": "Shock, Septic", "lang": "EN" }, { "name": "脓毒性休克", "lang": "CN" } ], [ { "name": "Hypotension", "lang": "EN" },...	[ "Small molecule drug" ]	Pending	-435,974,400,000	[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ] ]	[ "United States" ]
[ { "name": "利拉鲁肽", "lang": "CN" }, { "name": "Liraglutide", "lang": "EN" }, { "name": "リラグルチド（遺伝子組換え）", "lang": "JP" } ]	[ { "name": "Liraglutide (Genetical Recombination)", "lang": "EN" }, { "name": "Liraglutide Recombinant", "lang": "EN" }, { "name": "Saxenda", "lang": "EN" } ]	[ [ { "name": "Glucagon-like peptide 1 receptor", "lang": "EN" }, { "name": "胰高血糖素样肽-1受体", "lang": "CN" } ] ]	[ [ { "name": "Obesity", "lang": "EN" }, { "name": "肥胖", "lang": "CN" } ], [ { "name": "Overweight", "lang": "EN" }, { "name": "超重", "lang": "CN" } ], [ { "name": "Diabetes Mellitus, Type 2", "lang": "EN" }, ...	[ "Recombinant polypeptide" ]	Discontinued	1,246,320,000,000	[ [ { "name": "Diabetes Mellitus, Type 2", "lang": "EN" }, { "name": "2型糖尿病", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Canada", "Australia", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "卡妥索单抗", "lang": "CN" }, { "name": "Catumaxomab", "lang": "EN" } ]	[ { "name": "Anti-CD3 anti-EpCAM monoclonal antibody", "lang": "EN" }, { "name": "Anti-EpCAM anti-CD3 monoclonal antibody", "lang": "EN" }, { "name": "Catumaxomab (INN)", "lang": "EN" }, { "name": "catumaxomab", "lang": "EN" } ]	[ [ { "name": "T cell surface glycoprotein CD3", "lang": "EN" }, { "name": "T细胞表面糖蛋白CD3复合体", "lang": "CN" } ], [ { "name": "Epithelial cell adhesion molecule", "lang": "EN" }, { "name": "上皮细胞粘附分子", "lang": "CN" } ] ]	[ [ { "name": "EpCAM positive Solid Tumors", "lang": "EN" }, { "name": "EpCAM阳性实体瘤", "lang": "CN" } ], [ { "name": "Malignant ascites", "lang": "EN" }, { "name": "恶性腹水", "lang": "CN" } ], [ { "name": "Advanced gastric ca...	[ "Bispecific T-cell Engager (BiTE)" ]	Pending	1,240,185,600,000	[ [ { "name": "Malignant ascites", "lang": "EN" }, { "name": "恶性腹水", "lang": "CN" } ] ]	[ "European Union", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "依来沙多/依伐卡托/替扎卡托", "lang": "CN" }, { "name": "Elexacaftor/Ivacaftor/Tezacaftor", "lang": "EN" } ]	[ { "name": "ELX/TEZ/IVA", "lang": "EN" }, { "name": "Elexacaftor/ivacaftor/tezacaftor + ivacaftor", "lang": "EN" }, { "name": "Ivacaftor/tezacaftor/VX 445", "lang": "EN" }, { "name": "TRIKAFTA", "lang": "EN" }, { "name": "Tezacaftor/VX-445/ivacaftor", "lang": "...	[ [ { "name": "Cystic fibrosis transmembrane conductance regulator", "lang": "EN" }, { "name": "囊性纤维化跨膜传导调节因子", "lang": "CN" } ], [ { "name": "P-glycoprotein 1", "lang": "EN" }, { "name": "P-糖蛋白-1", "lang": "CN" } ] ]	[ [ { "name": "Cystic Fibrosis", "lang": "EN" }, { "name": "囊性纤维化", "lang": "CN" } ], [ { "name": "Cough", "lang": "EN" }, { "name": "咳嗽", "lang": "CN" } ], [ { "name": "Cystic fibrosis related diabetes", "lang": "...	[ "Small molecule drug" ]	Pending	1,571,616,000,000	[ [ { "name": "Cystic Fibrosis", "lang": "EN" }, { "name": "囊性纤维化", "lang": "CN" } ] ]	[ "United States", "European Union", "Canada", "Australia", "Switzerland", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "呼吸道合胞病毒疫苗（辉瑞大药厂）", "lang": "CN" }, { "name": "RSVpreF", "lang": "EN" } ]	[ { "name": "Respiratory Syncytial Virus Vaccine", "lang": "EN" }, { "name": "recombinant respiratory syncytial virus pre-fusion F protein, water for injections(Pfizer)", "lang": "EN" } ]	[ [ { "name": "Respiratory syncytial virus F protein", "lang": "EN" }, { "name": "呼吸道合胞病毒F蛋白", "lang": "CN" } ] ]	[ [ { "name": "Pneumonia due to respiratory syncytial virus", "lang": "EN" }, { "name": "呼吸道合胞病毒肺炎", "lang": "CN" } ], [ { "name": "Respiratory Syncytial Virus Infections", "lang": "EN" }, { "name": "呼吸道合胞体病毒感染", "lang": "CN" } ], ...	[ "Prophylactic vaccine" ]	Approved	1,672,790,400,000	[ [ { "name": "Lower Respiratory Tract Infections", "lang": "EN" }, { "name": "下呼吸道感染", "lang": "CN" } ] ]	[ "United States", "European Union", "Japan", "United Kingdom", "Canada", "Australia", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "曲尼司特", "lang": "CN" }, { "name": "Tranilast", "lang": "EN" }, { "name": "トラニラスト", "lang": "JP" } ]	[ { "name": "N-(3,4-Dimethoxycinnamoyl)anthranilic acid", "lang": "EN" }, { "name": "Tranilast (JP17/USAN/INN)", "lang": "EN" } ]	[ [ { "name": "Transforming growth factor beta", "lang": "EN" }, { "name": "转化生长因子β", "lang": "CN" } ] ]	[ [ { "name": "Conjunctivitis, Allergic", "lang": "EN" }, { "name": "变应性结膜炎", "lang": "CN" } ], [ { "name": "Idiopathic Pulmonary Fibrosis", "lang": "EN" }, { "name": "特发性肺纤维化", "lang": "CN" } ], [ { "name": "Corneal Dys...	[ "Small molecule drug" ]	Phase 1 Clinical	392,947,200,000	[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ] ]	[ "Japan" ]
[ { "name": "胰酶/纤维素酶/熊去氧胆酸/聚二甲基硅氧烷", "lang": "CN" }, { "name": "Pancreatin/Cellulase/Ursodeoxycholic Acid/Dimethicone", "lang": "EN" } ]	null	[ [ { "name": "Bile acid receptor FXR", "lang": "EN" }, { "name": "胆汁酸受体FXR", "lang": "CN" } ] ]	[ [ { "name": "Dyspepsia", "lang": "EN" }, { "name": "消化不良", "lang": "CN" } ] ]	[ "Enzyme" ]	Approved	1,751,932,800,000	[ [ { "name": "Dyspepsia", "lang": "EN" }, { "name": "消化不良", "lang": "CN" } ] ]	[ "South Korea" ]
[ { "name": "沙利鲁单抗", "lang": "CN" }, { "name": "Sarilumab", "lang": "EN" }, { "name": "サリルマブ（遺伝子組換え）", "lang": "JP" } ]	[ { "name": "Anti-IL 6 receptor antibody", "lang": "EN" }, { "name": "Anti-interleukin 6 receptor antibody", "lang": "EN" }, { "name": "Sarilumab (Genetical Recombination)", "lang": "EN" }, { "name": "Sarilumab (USAN)", "lang": "EN" }, { "name": "Sarilumab (genetica...	[ [ { "name": "Interleukin-6 receptor alpha subunit", "lang": "EN" }, { "name": "白细胞介素-6受体α亚基", "lang": "CN" } ] ]	[ [ { "name": "Polyarticular Juvenile Idiopathic Arthritis", "lang": "EN" }, { "name": "多关节型幼年特发性关节炎", "lang": "CN" } ], [ { "name": "Polymyalgia Rheumatica", "lang": "EN" }, { "name": "风湿性多肌痛", "lang": "CN" } ], [ { "na...	[ "Monoclonal antibody" ]	Phase 2 Clinical	1,484,179,200,000	[ [ { "name": "Rheumatoid Arthritis", "lang": "EN" }, { "name": "类风湿关节炎", "lang": "CN" } ] ]	[ "United States", "European Union", "Japan", "Canada", "Australia", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "阿司匹林/富马酸伏诺拉生", "lang": "CN" }, { "name": "Aspirin/Vonoprazan Fumarate", "lang": "EN" }, { "name": "アスピリン/ボノプラザンフマル酸塩", "lang": "JP" } ]	[ { "name": "TAK-438/Aspirin", "lang": "EN" }, { "name": "伏诺拉生/阿司匹林", "lang": "CN" } ]	[ [ { "name": "Cyclooxygenases", "lang": "EN" }, { "name": "环氧化酶", "lang": "CN" } ], [ { "name": "Potassium-transporting ATPase", "lang": "EN" }, { "name": "钾离子转运ATP酶复合体", "lang": "CN" } ], [ { "name": "Proton pump", ...	[ [ { "name": "Angina Pectoris", "lang": "EN" }, { "name": "心绞痛", "lang": "CN" } ], [ { "name": "Thromboembolism", "lang": "EN" }, { "name": "血栓栓塞", "lang": "CN" } ] ]	[ "Small molecule drug" ]	Approved	1,585,094,400,000	[ [ { "name": "Angina Pectoris", "lang": "EN" }, { "name": "心绞痛", "lang": "CN" } ], [ { "name": "Thromboembolism", "lang": "EN" }, { "name": "血栓栓塞", "lang": "CN" } ] ]	[ "Japan" ]
[ { "name": "非格司亭生物类似药 (泰福生技)", "lang": "CN" }, { "name": "Filgrastim-txid", "lang": "EN" } ]	[ { "name": "Filgrastim Biosimilar (Tanvex BioPharma, Inc.)", "lang": "EN" }, { "name": "非格司亭生物类似药（Tanvex BioPharma, Inc.）", "lang": "CN" } ]	[ [ { "name": "Colony stimulating factor 3 receptor", "lang": "EN" }, { "name": "巨噬细胞集落刺激因子3受体", "lang": "CN" } ] ]	[ [ { "name": "Febrile Neutropenia", "lang": "EN" }, { "name": "粒细胞减少性发热", "lang": "CN" } ], [ { "name": "Stem cell mobilisation", "lang": "EN" }, { "name": "干细胞动员", "lang": "CN" } ], [ { "name": "Neutropenia", "la...	[ "Biosimilar", "Colony-stimulating factors" ]	Approved	1,633,046,400,000	[ [ { "name": "Neutropenia", "lang": "EN" }, { "name": "中性粒细胞减少", "lang": "CN" } ] ]	[ "United States", "Canada" ]
[ { "name": "A型肉毒毒素 (Medytox)", "lang": "CN" }, { "name": "Botulinum toxin A(Medytox)", "lang": "EN" } ]	[ { "name": "Botulift", "lang": "EN" }, { "name": "Botulinum toxin A", "lang": "EN" }, { "name": "Cunox", "lang": "EN" }, { "name": "Innotox", "lang": "EN" }, { "name": "KbtxA", "lang": "EN" }, { "name": "Liquid-type botulinum toxin type A", "lang": ...	[ [ { "name": "Synaptosomal-associated protein 25", "lang": "EN" }, { "name": "突触相关蛋白25", "lang": "CN" } ] ]	[ [ { "name": "Benign Essential Blepharospasm", "lang": "EN" }, { "name": "良性基础型眼睑痉挛", "lang": "CN" } ], [ { "name": "Foot Deformities", "lang": "EN" }, { "name": "足部畸形", "lang": "CN" } ], [ { "name": "Glabellar frown li...	[ "Toxin" ]	Pending	1,142,467,200,000	[ [ { "name": "Benign Essential Blepharospasm", "lang": "EN" }, { "name": "良性基础型眼睑痉挛", "lang": "CN" } ], [ { "name": "Foot Deformities", "lang": "EN" }, { "name": "足部畸形", "lang": "CN" } ], [ { "name": "Glabellar frown li...	[ "South Korea", "Russia", "Taiwan Province" ]
[ { "name": "伊匹木单抗", "lang": "CN" }, { "name": "Ipilimumab", "lang": "EN" }, { "name": "イピリムマブ（遺伝子組換え）", "lang": "JP" } ]	[ { "name": "Anti CTLA-4 monoclonal antibody", "lang": "EN" }, { "name": "Anti-CTLA-4 Mab", "lang": "EN" }, { "name": "Ipilimumab (Genetical Recombination)", "lang": "EN" }, { "name": "伊匹单抗", "lang": "CN" }, { "name": "依匹木单抗", "lang": "CN" }, { "name": "...	[ [ { "name": "Cytotoxic T-Lymphocyte-Associated Antigen 4", "lang": "EN" }, { "name": "细胞毒性T淋巴细胞相关抗原4", "lang": "CN" } ] ]	[ [ { "name": "Microsatellite instability-high Rectal Cancer", "lang": "EN" }, { "name": "MSI-H 直肠癌", "lang": "CN" } ], [ { "name": "PD-L1 positive Non-Small Cell Lung Cancer", "lang": "EN" }, { "name": "PD-L1阳性非小细胞肺癌", "lang": "CN" }...	[ "Monoclonal antibody" ]	Discontinued	1,301,011,200,000	[ [ { "name": "Melanoma", "lang": "EN" }, { "name": "黑色素瘤", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "South Korea", "Liechtenstein", "Norway" ]
[ { "name": "Sulopenem etzadroxil/Probenecid", "lang": "EN" } ]	[ { "name": "Oral sulopenem", "lang": "EN" }, { "name": "Sulopenem etzadroxil", "lang": "EN" }, { "name": "Sulopenem etzadroxil (USAN)", "lang": "EN" } ]	[ [ { "name": "solute carrier family 22 member 6", "lang": "EN" } ], [ { "name": "Bacterial penicillin-binding protein", "lang": "EN" }, { "name": "细菌青霉素结合蛋白家族", "lang": "CN" } ] ]	[ [ { "name": "Urinary Tract Infections", "lang": "EN" }, { "name": "泌尿道感染", "lang": "CN" } ], [ { "name": "Bacterial Infections", "lang": "EN" }, { "name": "细菌感染", "lang": "CN" } ], [ { "name": "Community Acquired Pneum...	[ "Small molecule drug" ]	Phase 1 Clinical	1,729,814,400,000	[ [ { "name": "Urinary Tract Infections", "lang": "EN" }, { "name": "泌尿道感染", "lang": "CN" } ] ]	[ "United States" ]
[ { "name": "贝伐珠单抗生物类似药 (百奥泰生物)", "lang": "CN" }, { "name": "Bevacizumab biosimilar (Bio-Thera Solutions)", "lang": "EN" } ]	[ { "name": "BEVACIZUMAB-TNJN", "lang": "EN" }, { "name": "Bevacizumab Biosimilar (Bio-Thera Solutions, Ltd.)", "lang": "EN" }, { "name": "贝伐珠单抗生物类似药（百奥泰生物制药股份有限公司）", "lang": "CN" } ]	[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]	[ [ { "name": "Advanced Renal Cell Carcinoma", "lang": "EN" }, { "name": "晚期肾细胞癌", "lang": "CN" } ], [ { "name": "EGFR positive Non-squamous non-small cell lung cancer", "lang": "EN" }, { "name": "EGFR阳性非鳞状非小细胞肺癌", "lang": "CN" } ],...	[ "Biosimilar", "Monoclonal antibody" ]	Approved	1,637,107,200,000	[ [ { "name": "Metastatic Colorectal Carcinoma", "lang": "EN" }, { "name": "转移性结直肠癌", "lang": "CN" } ], [ { "name": "Non-Small Cell Lung Cancer", "lang": "EN" }, { "name": "非小细胞肺癌", "lang": "CN" } ] ]	[ "United States", "China", "European Union", "Brazil", "Iceland", "Liechtenstein", "Norway" ]
[ { "name": "利美索龙", "lang": "CN" }, { "name": "Rimexolone", "lang": "EN" } ]	[ { "name": "Rimexel", "lang": "EN" }, { "name": "Rimexolon", "lang": "EN" }, { "name": "Rimexolone (USP/INN)", "lang": "EN" }, { "name": "Trimexolone", "lang": "EN" }, { "name": "Vexolon", "lang": "EN" } ]	[ [ { "name": "Glucocorticoid receptor", "lang": "EN" }, { "name": "糖皮质激素受体", "lang": "CN" } ] ]	[ [ { "name": "Uveitis", "lang": "EN" }, { "name": "葡萄膜炎", "lang": "CN" } ], [ { "name": "Dry Eye Syndromes", "lang": "EN" }, { "name": "干眼综合征", "lang": "CN" } ], [ { "name": "Post procedural inflammation", "lang":...	[ "Small molecule drug" ]	Withdrawn	788,745,600,000	[ [ { "name": "Post procedural inflammation", "lang": "EN" }, { "name": "术后炎症", "lang": "CN" } ], [ { "name": "Uveitis, Anterior", "lang": "EN" }, { "name": "前葡萄膜炎", "lang": "CN" } ] ]	[ "Germany" ]
[ { "name": "缬沙坦/苯磺酸氨氯地平/匹伐他汀钙水合物", "lang": "CN" }, { "name": "Valsartan/Amlodipine Besylate/Pitavastatin Calcium Hydrate", "lang": "EN" } ]	null	[ [ { "name": "HMG-CoA reductase", "lang": "EN" }, { "name": "羟甲基戊二酰辅酶A合酶", "lang": "CN" } ], [ { "name": "Angiotensin II Receptor Type 1", "lang": "EN" }, { "name": "血管紧张素II-1型受体", "lang": "CN" } ], [ { "name": "Voltage...	[ [ { "name": "Essential Hypertension", "lang": "EN" }, { "name": "原发性高血压", "lang": "CN" } ], [ { "name": "Primary hypercholesterolemia", "lang": "EN" }, { "name": "原发性高胆固醇血症", "lang": "CN" } ] ]	[ "Small molecule drug" ]	Approved	1,758,672,000,000	[ [ { "name": "Essential Hypertension", "lang": "EN" }, { "name": "原发性高血压", "lang": "CN" } ], [ { "name": "Primary hypercholesterolemia", "lang": "EN" }, { "name": "原发性高胆固醇血症", "lang": "CN" } ] ]	[ "South Korea" ]

[ { "name": "胰酶/纤维素酶/熊去氧胆酸/西甲硅油", "lang": "CN" }, { "name": "Pancreatin/Cellulase/Ursodeoxycholic Acid/Simethicone", "lang": "EN" } ]

null

[ [ { "name": "Bile acid receptor FXR", "lang": "EN" }, { "name": "胆汁酸受体FXR", "lang": "CN" } ] ]

[ [ { "name": "Dyspepsia", "lang": "EN" }, { "name": "消化不良", "lang": "CN" } ] ]

[ "Enzyme" ]

Approved

1,708,560,000,000

[ [ { "name": "Dyspepsia", "lang": "EN" }, { "name": "消化不良", "lang": "CN" } ] ]

[ "South Korea" ]

[ { "name": "甲磺酸阿帕替尼", "lang": "CN" }, { "name": "Apatinib Mesylate", "lang": "EN" } ]

[ { "name": "Apatinib", "lang": "EN" }, { "name": "Rivoceranib", "lang": "EN" }, { "name": "Rivoceranib Mesylate(USAN)", "lang": "EN" }, { "name": "Rivoceranib mesilate", "lang": "EN" } ]

[ [ { "name": "Vascular endothelial growth factor receptor 2", "lang": "EN" }, { "name": "血管内皮细胞生长因子受体2", "lang": "CN" } ] ]

[ [ { "name": "Germline BRCA-mutated, HER2-negative metastatic breast cancer", "lang": "EN" }, { "name": "gBRCA突变/HER2阴性乳腺癌", "lang": "CN" } ], [ { "name": "Hepatocellular Carcinoma", "lang": "EN" }, { "name": "肝细胞癌", "lang": "CN" } ...

[ "Small molecule drug" ]

Pending

1,413,504,000,000

[ [ { "name": "Gastroesophageal junction adenocarcinoma", "lang": "EN" }, { "name": "胃食管交界处腺癌", "lang": "CN" } ], [ { "name": "stomach adenocarcinoma", "lang": "EN" }, { "name": "胃腺癌", "lang": "CN" } ] ]

[ "China" ]

[ { "name": "替本福司", "lang": "CN" }, { "name": "Tebentafusp", "lang": "EN" } ]

[ { "name": "Monoclonal T cell receptor anti-CD3 scFv fusion protein", "lang": "EN" }, { "name": "Tebentafusp-TEBN", "lang": "EN" } ]

[ [ { "name": "T cell surface glycoprotein CD3", "lang": "EN" }, { "name": "T细胞表面糖蛋白CD3复合体", "lang": "CN" } ], [ { "name": "Melanocyte protein PMEL", "lang": "EN" }, { "name": "黑素细胞蛋白PMEL", "lang": "CN" } ] ]

[ [ { "name": "Melanoma", "lang": "EN" }, { "name": "黑色素瘤", "lang": "CN" } ], [ { "name": "Uveal Melanoma", "lang": "EN" }, { "name": "葡萄膜黑色素瘤", "lang": "CN" } ], [ { "name": "Unresectable Melanoma", "lang": "EN" ...

[ "Bispecific T-cell Engager (BiTE)", "TCR fusion protein" ]

Approved

1,643,068,800,000

[ [ { "name": "Uveal Melanoma", "lang": "EN" }, { "name": "葡萄膜黑色素瘤", "lang": "CN" } ] ]

[ "United States", "European Union", "United Kingdom", "Canada", "Australia", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "克林霉素磷酸酯/维A酸", "lang": "CN" }, { "name": "Clindamycin Phosphate/Tretinoin", "lang": "EN" } ]

null

[ [ { "name": "50S ribosomal subunit", "lang": "EN" }, { "name": "50S核糖体亚基", "lang": "CN" } ], [ { "name": "Retinoic acid receptor alpha", "lang": "EN" }, { "name": "维甲酸受体α", "lang": "CN" } ], [ { "name": "Retinoic acid ...

[ [ { "name": "Acne Vulgaris", "lang": "EN" }, { "name": "寻常痤疮", "lang": "CN" } ], [ { "name": "Rosacea", "lang": "EN" }, { "name": "玫瑰痤疮", "lang": "CN" } ] ]

[ "Small molecule drug" ]

Pending

1,162,857,600,000

[ [ { "name": "Acne Vulgaris", "lang": "EN" }, { "name": "寻常痤疮", "lang": "CN" } ] ]

[ "United States", "Australia" ]

[ { "name": "头孢他啶", "lang": "CN" }, { "name": "Ceftazidime", "lang": "EN" }, { "name": "セフタジジム水和物", "lang": "JP" } ]

[ { "name": "CAZ", "lang": "EN" }, { "name": "Ceftazidime (INN)", "lang": "EN" }, { "name": "Ceftazidime Hydrate", "lang": "EN" }, { "name": "Ceftazidime Sodium Carbonate", "lang": "EN" }, { "name": "Ceftazidime and Sodium Chloride", "lang": "EN" }, { "n...

[ [ { "name": "Bacterial penicillin-binding protein", "lang": "EN" }, { "name": "细菌青霉素结合蛋白家族", "lang": "CN" } ] ]

[ [ { "name": "Bacterial Infections", "lang": "EN" }, { "name": "细菌感染", "lang": "CN" } ], [ { "name": "Adnexitis", "lang": "EN" }, { "name": "附件炎", "lang": "CN" } ], [ { "name": "Endocarditis, Bacterial", "lang": "...

[ "Small molecule drug" ]

Withdrawn

410,227,200,000

[ [ { "name": "Gram-Negative Bacterial Infections", "lang": "EN" }, { "name": "革兰氏阴性菌感染", "lang": "CN" } ], [ { "name": "Gram-Positive Bacterial Infections", "lang": "EN" }, { "name": "革兰氏阳性细菌感染", "lang": "CN" } ] ]

[ "China", "Japan" ]

[ { "name": "帕西妥莫单抗", "lang": "CN" }, { "name": "Moxetumomab Pasudotox-TDFK", "lang": "EN" } ]

[ { "name": "Moxetumomab pasudotox", "lang": "EN" }, { "name": "Moxetumomab pasudotox (USAN/INN)", "lang": "EN" }, { "name": "莫塞妥莫单抗", "lang": "CN" } ]

[ [ { "name": "CD22", "lang": "EN" }, { "name": "CD22蛋白", "lang": "CN" } ] ]

[ [ { "name": "Hairy Cell Leukemia", "lang": "EN" }, { "name": "毛细胞白血病", "lang": "CN" } ], [ { "name": "Adult Lymphoblastic Lymphoma", "lang": "EN" }, { "name": "淋巴母细胞淋巴瘤", "lang": "CN" } ], [ { "name": "B-Cell Lymphoma"...

[ "Antibody toxin conjugate" ]

Pending

1,536,796,800,000

[ [ { "name": "Hairy Cell Leukemia", "lang": "EN" }, { "name": "毛细胞白血病", "lang": "CN" } ] ]

[ "United States" ]

[ { "name": "谷胱甘肽/肌苷", "lang": "CN" }, { "name": "Glutathione/Inosine", "lang": "EN" } ]

[ { "name": "Molixan", "lang": "EN" } ]

[ [ { "name": "Beta-nerve growth factor", "lang": "EN" }, { "name": "β-神经生长因子", "lang": "CN" } ] ]

[ [ { "name": "Hepatitis B", "lang": "EN" }, { "name": "乙型肝炎", "lang": "CN" } ], [ { "name": "Hepatitis C", "lang": "EN" }, { "name": "丙型肝炎", "lang": "CN" } ], [ { "name": "Chronic hepatitis C genotype 1", "lang": ...

[ "Small molecule drug" ]

Pending

1,157,846,400,000

[ [ { "name": "Hepatitis C", "lang": "EN" }, { "name": "丙型肝炎", "lang": "CN" } ] ]

[ "Russia" ]

[ { "name": "奥马珠单抗生物类似药(Generium Pharmaceuticals)", "lang": "CN" }, { "name": "Omalizumab biosimilar (Generium Pharmaceuticals)", "lang": "EN" } ]

[ { "name": "Omalizumab Biosimilar", "lang": "EN" }, { "name": "奥马佐单抗生物类似药(Generium Pharmaceuticals)", "lang": "CN" }, { "name": "奥马珠单抗生物类似药", "lang": "CN" } ]

[ [ { "name": "Immunoglobulin E", "lang": "EN" }, { "name": "免疫球蛋白E", "lang": "CN" } ] ]

[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ], [ { "name": "Chronic Urticaria", "lang": "EN" }, { "name": "慢性荨麻疹", "lang": "CN" } ], [ { "name": "Allergic asthma", "lang": "EN" }, ...

[ "Biosimilar", "Monoclonal antibody" ]

Approved

1,644,364,800,000

[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ], [ { "name": "Chronic Urticaria", "lang": "EN" }, { "name": "慢性荨麻疹", "lang": "CN" } ] ]

[ "Russia" ]

[ { "name": "门冬胰岛素 (宜昌东阳光长江药业)", "lang": "CN" }, { "name": "Insulin Aspart Biosimilar (YiChang HEC ChangJiang Pharmaceutical )", "lang": "EN" } ]

null

[ [ { "name": "Insulin receptor", "lang": "EN" }, { "name": "胰岛素受体", "lang": "CN" } ] ]

[ [ { "name": "Diabetes Mellitus", "lang": "EN" }, { "name": "糖尿病", "lang": "CN" } ], [ { "name": "Diabetes Mellitus, Type 2", "lang": "EN" }, { "name": "2型糖尿病", "lang": "CN" } ] ]

[ "Biosimilar", "Peptide Hormone" ]

Pending

1,665,446,400,000

[ [ { "name": "Diabetes Mellitus", "lang": "EN" }, { "name": "糖尿病", "lang": "CN" } ] ]

[ "China" ]

[ { "name": "特丁胺培哚普利", "lang": "CN" }, { "name": "Perindopril Erbumine", "lang": "EN" }, { "name": "ペリンドプリルエルブミン", "lang": "JP" } ]

[ { "name": "Perindopril erbumine (JAN/USP)", "lang": "EN" }, { "name": "Perindopril tert-Butylamine", "lang": "EN" }, { "name": "perindopril", "lang": "EN" }, { "name": "培哚普利", "lang": "CN" }, { "name": "培哚普利叔丁胺", "lang": "CN" }, { "name": "培哚普利叔丁胺盐", ...

[ [ { "name": "Angiotensin-converting enzyme", "lang": "EN" }, { "name": "血管紧张素转化酶", "lang": "CN" } ] ]

[ [ { "name": "Heart Failure", "lang": "EN" }, { "name": "心脏衰竭", "lang": "CN" } ], [ { "name": "Hypertension", "lang": "EN" }, { "name": "高血压", "lang": "CN" } ], [ { "name": "Agranulocytosis", "lang": "EN" }, ...

[ "Small molecule drug" ]

Withdrawn

757,209,600,000

[ [ { "name": "Agranulocytosis", "lang": "EN" }, { "name": "粒细胞减少症", "lang": "CN" } ], [ { "name": "Angioedema", "lang": "EN" }, { "name": "血管性水肿", "lang": "CN" } ], [ { "name": "Cardiovascular Diseases", "lang": "...

[ "China", "Japan", "Canada" ]

[ { "name": "莱博雷生", "lang": "CN" }, { "name": "Lemborexant", "lang": "EN" }, { "name": "レンボレキサント", "lang": "JP" } ]

[ { "name": "DAYVIGOTM", "lang": "EN" }, { "name": "LEM", "lang": "EN" }, { "name": "Lemborexant (JAN/USAN/INN)", "lang": "EN" } ]

[ [ { "name": "Orexin receptor", "lang": "EN" }, { "name": "食欲素受体", "lang": "CN" } ] ]

[ [ { "name": "Sleep Initiation and Maintenance Disorders", "lang": "EN" }, { "name": "入睡和睡眠障碍", "lang": "CN" } ], [ { "name": "Emergence Delirium", "lang": "EN" }, { "name": "苏醒期谵妄", "lang": "CN" } ], [ { "name": "Sleep...

[ "Small molecule drug" ]

Phase 2 Clinical

1,567,468,800,000

[ [ { "name": "Sleep Initiation and Maintenance Disorders", "lang": "EN" }, { "name": "入睡和睡眠障碍", "lang": "CN" } ] ]

[ "United States", "China", "Japan", "Canada", "Australia", "India", "Hong Kong", "Malaysia", "Taiwan Province" ]

[ { "name": "门冬胰岛素生物类似药(Biocon Ltd.)", "lang": "CN" }, { "name": "Insulin aspart-xjhz", "lang": "EN" } ]

[ { "name": "Insulin aspart Biosimilar (Biocon Biologics, Inc.)", "lang": "EN" }, { "name": "Kixelle", "lang": "EN" }, { "name": "门冬胰岛素生物类似药（Biocon Biologics, Inc.）", "lang": "CN" } ]

[ [ { "name": "Insulin receptor", "lang": "EN" }, { "name": "胰岛素受体", "lang": "CN" } ] ]

[ [ { "name": "Diabetes Mellitus", "lang": "EN" }, { "name": "糖尿病", "lang": "CN" } ], [ { "name": "Diabetes Mellitus, Type 1", "lang": "EN" }, { "name": "1型糖尿病", "lang": "CN" } ] ]

[ "Biosimilar", "Peptide Hormone" ]

Discontinued

1,612,483,200,000

[ [ { "name": "Diabetes Mellitus", "lang": "EN" }, { "name": "糖尿病", "lang": "CN" } ] ]

[ "United States", "European Union", "Canada", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "乳酸帕比司他", "lang": "CN" }, { "name": "Panobinostat lactate", "lang": "EN" }, { "name": "パノビノスタット乳酸塩", "lang": "JP" } ]

[ { "name": "Faridak", "lang": "EN" }, { "name": "Panobinostat", "lang": "EN" }, { "name": "Panobinostat lactate (JAN)", "lang": "EN" }, { "name": "panobinostat", "lang": "EN" }, { "name": "panobinostat free base", "lang": "EN" }, { "name": "panobinostat...

[ [ { "name": "Histone deacetylase", "lang": "EN" }, { "name": "组蛋白去乙酰化酶家族", "lang": "CN" } ] ]

[ [ { "name": "Multiple Myeloma", "lang": "EN" }, { "name": "多发性骨髓瘤", "lang": "CN" } ], [ { "name": "Medulloblastoma", "lang": "EN" }, { "name": "髓母细胞瘤", "lang": "CN" } ], [ { "name": "Acute Chest Syndrome", "lang"...

[ "Small molecule drug" ]

Pending

1,424,649,600,000

[ [ { "name": "Multiple Myeloma", "lang": "EN" }, { "name": "多发性骨髓瘤", "lang": "CN" } ] ]

[ "European Union", "Japan", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "洛匹那韦/利托那韦", "lang": "CN" }, { "name": "Lopinavir/Ritonavir", "lang": "EN" }, { "name": "ロピナビル/リトナビル", "lang": "JP" } ]

[ { "name": "ABT-378/Ritonavir", "lang": "EN" }, { "name": "DARE-HPV", "lang": "EN" }, { "name": "LPV/RTV", "lang": "EN" }, { "name": "Lopinavir and Ritonavir", "lang": "EN" }, { "name": "Lopinavir/Ritonavir", "lang": "EN" }, { "name": "利托那韦/洛匹那韦", "...

[ [ { "name": "Human immunodeficiency virus type 1 Pol protein", "lang": "EN" }, { "name": "人类免疫缺陷病毒1型 Pol 蛋白", "lang": "CN" } ] ]

[ [ { "name": "HIV Infections", "lang": "EN" }, { "name": "HIV感染", "lang": "CN" } ], [ { "name": "Human Papillomavirus-Related Cervical Carcinoma", "lang": "EN" }, { "name": "人瘤病毒相关性宫颈癌", "lang": "CN" } ], [ { "name": "H...

[ "Small molecule drug" ]

Discontinued

968,976,000,000

[ [ { "name": "HIV Infections", "lang": "EN" }, { "name": "HIV感染", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "阿立哌唑十二烷酸酯", "lang": "CN" }, { "name": "Aripiprazole Lauroxil", "lang": "EN" } ]

[ { "name": "ALNCD", "lang": "EN" }, { "name": "ARISTADA INITIO", "lang": "EN" }, { "name": "Aripiprazole lauroxil (USAN)", "lang": "EN" } ]

[ [ { "name": "Serotonin 1a (5-HT1a) receptor", "lang": "EN" }, { "name": "5-羟色胺1A受体", "lang": "CN" } ], [ { "name": "Serotonin 2a (5-HT2a) receptor", "lang": "EN" }, { "name": "5-羟色胺2A受体", "lang": "CN" } ], [ { "name": ...

[ [ { "name": "Schizophrenia", "lang": "EN" }, { "name": "精神分裂症", "lang": "CN" } ], [ { "name": "Chronic schizophrenia", "lang": "EN" }, { "name": "慢性精神分裂症", "lang": "CN" } ], [ { "name": "Schizoaffective disorder", ...

[ "Small molecule drug" ]

Pending

1,444,003,200,000

[ [ { "name": "Schizophrenia", "lang": "EN" }, { "name": "精神分裂症", "lang": "CN" } ] ]

[ "United States" ]

[ { "name": "福巴替尼", "lang": "CN" }, { "name": "Futibatinib", "lang": "EN" }, { "name": "フチバチニブ", "lang": "JP" } ]

[ { "name": "Futibatinib (JAN/USAN/INN)", "lang": "EN" }, { "name": "福替巴替尼", "lang": "CN" } ]

[ [ { "name": "Fibroblast growth factor receptor 1", "lang": "EN" }, { "name": "成纤维细胞生长因子受体-1", "lang": "CN" } ], [ { "name": "Fibroblast growth factor receptor 2", "lang": "EN" }, { "name": "成纤维细胞生长因子受体-2", "lang": "CN" } ], [ ...

[ [ { "name": "FGFR2 fusion or rearranged Cholangiocarcinoma", "lang": "EN" }, { "name": "FGFR2融合或重排的胆管癌", "lang": "CN" } ], [ { "name": "Intrahepatic Cholangiocarcinoma", "lang": "EN" }, { "name": "肝内胆管癌", "lang": "CN" } ], [ ...

[ "Small molecule drug" ]

Phase 1/2 Clinical

1,664,496,000,000

[ [ { "name": "Intrahepatic Cholangiocarcinoma", "lang": "EN" }, { "name": "肝内胆管癌", "lang": "CN" } ] ]

[ "United States", "European Union", "Japan", "Australia", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "富马酸安奈克替尼", "lang": "CN" }, { "name": "Unecritinib", "lang": "EN" } ]

[ { "name": "安奈克替尼", "lang": "CN" } ]

[ [ { "name": "Anaplastic lymphoma kinase", "lang": "EN" }, { "name": "间变性淋巴瘤激酶", "lang": "CN" } ], [ { "name": "Proto-oncogene tyrosine-protein kinase ROS", "lang": "EN" }, { "name": "原癌基因酪氨酸蛋白激酶ROS", "lang": "CN" } ], [ { ...

[ [ { "name": "Reactive oxygen species 1 positive non-small cell lung cancer", "lang": "EN" }, { "name": "ROS1阳性非小细胞肺癌", "lang": "CN" } ], [ { "name": "Advanced cancer", "lang": "EN" }, { "name": "晚期癌症", "lang": "CN" } ], [ { ...

[ "Small molecule drug" ]

Discontinued

1,713,916,800,000

[ [ { "name": "Reactive oxygen species 1 positive non-small cell lung cancer", "lang": "EN" }, { "name": "ROS1阳性非小细胞肺癌", "lang": "CN" } ] ]

[ "China" ]

[ { "name": "安立生坦", "lang": "CN" }, { "name": "Ambrisentan", "lang": "EN" }, { "name": "アンブリセンタン", "lang": "JP" } ]

[ { "name": "(2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid", "lang": "EN" }, { "name": "Ambrisentan (JAN/INN)", "lang": "EN" } ]

[ [ { "name": "Endothelin receptor type A", "lang": "EN" }, { "name": "内皮素A受体", "lang": "CN" } ] ]

[ [ { "name": "Pulmonary arterial hypertension associated with connective tissue disease", "lang": "EN" }, { "name": "与结缔组织病相关的肺动脉高压", "lang": "CN" } ], [ { "name": "Idiopathic pulmonary arterial hypertension", "lang": "EN" }, { "name": "特发性肺动脉...

[ "Small molecule drug" ]

Pending

1,181,865,600,000

[ [ { "name": "Pulmonary Arterial Hypertension", "lang": "EN" }, { "name": "肺动脉高压", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "A型肉毒毒素 (Biotecon)", "lang": "CN" }, { "name": "Incobotulinum toxinA (Biotecon)", "lang": "EN" }, { "name": "インコボツリヌストキシンA", "lang": "JP" } ]

[ { "name": "Botulinum toxin A", "lang": "EN" }, { "name": "Botulinum toxin A (Merz Pharma)", "lang": "EN" }, { "name": "Incobotulinum toxin A", "lang": "EN" }, { "name": "IncobotulinumtoxinA", "lang": "EN" }, { "name": "Zeomaine", "lang": "EN" }, { "nam...

[ [ { "name": "Synaptosomal-associated protein 25", "lang": "EN" }, { "name": "突触相关蛋白25", "lang": "CN" } ] ]

[ [ { "name": "cervical dystonia", "lang": "EN" }, { "name": "颈肌张力障碍", "lang": "CN" } ], [ { "name": "Crow's feet", "lang": "EN" }, { "name": "鱼尾纹", "lang": "CN" } ], [ { "name": "Forehead lines", "lang": "EN" ...

[ "Toxin" ]

Pending

1,193,184,000,000

[ [ { "name": "Sialorrhea", "lang": "EN" }, { "name": "流涎", "lang": "CN" } ], [ { "name": "Spasm", "lang": "EN" }, { "name": "痉挛", "lang": "CN" } ] ]

[ "United States", "China", "Japan", "United Kingdom", "Canada", "Australia", "Austria", "Belgium", "Bulgaria", "Cyprus", "Czechia", "Germany", "Denmark", "Estonia", "Spain", "Finland", "France", "Greece", "Croatia", "Hungary", "Ireland", "Iceland", "Italy", "Liechtenstei...

[ { "name": "布比卡因/美洛昔康", "lang": "CN" }, { "name": "Bupivacaine/Meloxicam", "lang": "EN" } ]

[ { "name": "Meloxicam/bupivacaine", "lang": "EN" }, { "name": "ZYNRELEF", "lang": "EN" } ]

[ [ { "name": "Cyclooxygenase-1", "lang": "EN" }, { "name": "环氧化酶-1", "lang": "CN" } ], [ { "name": "Cyclooxygenase-2", "lang": "EN" }, { "name": "环氧化酶-2", "lang": "CN" } ], [ { "name": "Sodium voltage-gated channel alph...

[ [ { "name": "Pain, Postoperative", "lang": "EN" }, { "name": "术后疼痛", "lang": "CN" } ], [ { "name": "Analgesia", "lang": "EN" }, { "name": "镇痛", "lang": "CN" } ], [ { "name": "Bunion", "lang": "EN" }, { ...

[ "Small molecule drug" ]

Pending

1,600,905,600,000

[ [ { "name": "Pain, Postoperative", "lang": "EN" }, { "name": "术后疼痛", "lang": "CN" } ] ]

[ "United States", "Canada" ]

[ { "name": "盐酸胍法辛", "lang": "CN" }, { "name": "Guanfacine hydrochloride", "lang": "EN" }, { "name": "グアンファシン塩酸塩", "lang": "JP" } ]

[ { "name": "Connexyn", "lang": "EN" }, { "name": "Guanfacine XR", "lang": "EN" }, { "name": "Guanfacine hydrochloride (JAN/USP)", "lang": "EN" }, { "name": "Intuniv XR", "lang": "EN" }, { "name": "guanfacine", "lang": "EN" } ]

[ [ { "name": "Adrenergic receptors", "lang": "EN" }, { "name": "肾上腺素能受体家族", "lang": "CN" } ] ]

[ [ { "name": "Attention Deficit Disorder With Hyperactivity", "lang": "EN" }, { "name": "注意缺陷障碍伴多动", "lang": "CN" } ], [ { "name": "Anxiety, Separation", "lang": "EN" }, { "name": "分离性焦虑", "lang": "CN" } ], [ { "name": ...

[ "Small molecule drug" ]

Discontinued

530,755,200,000

[ [ { "name": "Hypertension", "lang": "EN" }, { "name": "高血压", "lang": "CN" } ] ]

[ "United States", "European Union", "Japan", "Australia", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "盐酸头孢替安酯", "lang": "CN" }, { "name": "Cefotiam hexetil hydrochloride", "lang": "EN" } ]

[ { "name": "Cefotiam hexetil hydrochloride (JP17)", "lang": "EN" } ]

[ [ { "name": "Alpha-2a adrenergic receptor", "lang": "EN" }, { "name": "肾上腺素能受体α-2a", "lang": "CN" } ] ]

[ [ { "name": "Abscess", "lang": "EN" }, { "name": "脓肿", "lang": "CN" } ], [ { "name": "Burn infections", "lang": "EN" }, { "name": "烧伤感染", "lang": "CN" } ], [ { "name": "Cystitis", "lang": "EN" }, { ...

[ "Small molecule drug" ]

Pending

631,152,000,000

[ [ { "name": "Abscess", "lang": "EN" }, { "name": "脓肿", "lang": "CN" } ], [ { "name": "Burn infections", "lang": "EN" }, { "name": "烧伤感染", "lang": "CN" } ], [ { "name": "Cystitis", "lang": "EN" }, { ...

[ "Japan" ]

[ { "name": "那昔妥单抗", "lang": "CN" }, { "name": "Naxitamab", "lang": "EN" } ]

[ { "name": "Anti-Gd2 igg3 monoclonal antibody 3F8 humanized", "lang": "EN" }, { "name": "Anti-Gd2 monoclonal antibody 3F8 humanized", "lang": "EN" }, { "name": "Humanised 3F8", "lang": "EN" }, { "name": "Humanised IgG1 monoclonal GD2 antibody", "lang": "EN" }, { "n...

[ [ { "name": "Disialoganglioside GD2", "lang": "EN" }, { "name": "唾液神经节苷脂GD2", "lang": "CN" } ] ]

[ [ { "name": "High Risk Neuroblastoma", "lang": "EN" }, { "name": "高风险神经母细胞瘤", "lang": "CN" } ], [ { "name": "Refractory Neuroblastoma", "lang": "EN" }, { "name": "难治性神经母细胞瘤", "lang": "CN" } ], [ { "name": "Ganglioneuro...

[ "Monoclonal antibody" ]

Phase 2 Clinical

1,606,262,400,000

[ [ { "name": "High Risk Neuroblastoma", "lang": "EN" }, { "name": "高风险神经母细胞瘤", "lang": "CN" } ] ]

[ "United States", "China", "Brazil", "Israel" ]

[ { "name": "奥布替尼", "lang": "CN" }, { "name": "Orelabrutinib", "lang": "EN" } ]

[ { "name": "Obrutinib", "lang": "EN" }, { "name": "abutinib", "lang": "EN" } ]

[ [ { "name": "Tyrosine-protein kinase BTK", "lang": "EN" }, { "name": "酪氨酸蛋白激酶BTK", "lang": "CN" } ] ]

[ [ { "name": "Marginal zone lymphoma recurrent", "lang": "EN" }, { "name": "复发性边缘区淋巴瘤", "lang": "CN" } ], [ { "name": "Refractory Marginal Zone Lymphoma", "lang": "EN" }, { "name": "难治性边缘区淋巴瘤", "lang": "CN" } ], [ { "na...

[ "Small molecule drug" ]

Approved

1,608,854,400,000

[ [ { "name": "Chronic Lymphocytic Leukemia", "lang": "EN" }, { "name": "慢性淋巴细胞白血病", "lang": "CN" } ], [ { "name": "Mantle-Cell Lymphoma", "lang": "EN" }, { "name": "套细胞淋巴瘤", "lang": "CN" } ], [ { "name": "Small Lymphocy...

[ "China", "Singapore" ]

[ { "name": "枸橼酸莫沙必利", "lang": "CN" }, { "name": "Mosapride Citrate Hydrate", "lang": "EN" }, { "name": "モサプリドクエン酸塩水和物", "lang": "JP" } ]

[ { "name": "Mosapride Citrate", "lang": "EN" }, { "name": "Mosapride citrate dihydrate", "lang": "EN" }, { "name": "Mosapride citrate hydrate (JP17)", "lang": "EN" } ]

[ [ { "name": "Serotonin 4 (5-HT4) receptor", "lang": "EN" }, { "name": "5-羟色胺受体4", "lang": "CN" } ] ]

[ [ { "name": "Gastritis", "lang": "EN" }, { "name": "胃炎", "lang": "CN" } ], [ { "name": "Urinary Calculi", "lang": "EN" }, { "name": "泌尿结石", "lang": "CN" } ], [ { "name": "Chronic gastritis", "lang": "EN" }, ...

[ "Small molecule drug" ]

Phase 2 Clinical

899,164,800,000

[ [ { "name": "Chronic gastritis", "lang": "EN" }, { "name": "慢性胃炎", "lang": "CN" } ] ]

[ "China", "Japan" ]

[ { "name": "Vandefitemcel", "lang": "EN" }, { "name": "バンデフィテムセル", "lang": "JP" } ]

[ { "name": "Modified bone marrow derived mesenchymal stem cells - SanBio", "lang": "EN" } ]

[ [ { "name": "Nerve growth factor", "lang": "EN" }, { "name": "神经生长因子", "lang": "CN" } ] ]

[ [ { "name": "Brain Injuries, Traumatic", "lang": "EN" }, { "name": "创伤性脑损伤", "lang": "CN" } ], [ { "name": "Hemorrhagic stroke", "lang": "EN" }, { "name": "出血性卒中", "lang": "CN" } ], [ { "name": "Ischemic stroke", ...

[ "Mesenchymal stem cell therapy" ]

Preclinical

1,722,384,000,000

[ [ { "name": "Brain Injuries, Traumatic", "lang": "EN" }, { "name": "创伤性脑损伤", "lang": "CN" } ] ]

[ "Japan" ]

[ { "name": "奥贝胆酸", "lang": "CN" }, { "name": "Obeticholic acid", "lang": "EN" } ]

[ { "name": "(3α,5β,6α,7α)-6-ethyl-3,7-dihydroxycholan-24-oic acid", "lang": "EN" }, { "name": "6-Ethyl-CDCA", "lang": "EN" }, { "name": "6-ethyl-chenodeoxycholic-acid", "lang": "EN" }, { "name": "6-ethylchenodeoxycholic acid", "lang": "EN" }, { "name": "6alpha-Ethy...

[ [ { "name": "Bile acid receptor FXR", "lang": "EN" }, { "name": "胆汁酸受体FXR", "lang": "CN" } ] ]

[ [ { "name": "Primary Biliary Cholangitis", "lang": "EN" }, { "name": "原发性胆汁性胆管炎", "lang": "CN" } ], [ { "name": "Fibrosis, Liver", "lang": "EN" }, { "name": "肝纤维化", "lang": "CN" } ], [ { "name": "Biliary Atresia", ...

[ "Small molecule drug" ]

NDA/BLA

1,464,307,200,000

[ [ { "name": "Primary Biliary Cholangitis", "lang": "EN" }, { "name": "原发性胆汁性胆管炎", "lang": "CN" } ] ]

[ "Australia" ]

[ { "name": "司来帕格", "lang": "CN" }, { "name": "Selexipag", "lang": "EN" }, { "name": "セレキシパグ", "lang": "JP" } ]

[ { "name": "Selexipag (JAN/USAN/INN)", "lang": "EN" }, { "name": "赛乐西帕", "lang": "CN" } ]

[ [ { "name": "Prostanoid IP receptor", "lang": "EN" }, { "name": "前列腺素IP受体", "lang": "CN" } ] ]

[ [ { "name": "Chronic thromboembolic pulmonary hypertension", "lang": "EN" }, { "name": "慢性血栓栓塞性肺动脉高压", "lang": "CN" } ], [ { "name": "Pulmonary Arterial Hypertension", "lang": "EN" }, { "name": "肺动脉高压", "lang": "CN" } ], [ {...

[ "Small molecule drug" ]

Pending

1,450,656,000,000

[ [ { "name": "Pulmonary Arterial Hypertension", "lang": "EN" }, { "name": "肺动脉高压", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Canada", "Australia", "Switzerland", "Iceland", "South Korea", "Liechtenstein", "Norway" ]

[ { "name": "醋酸阿比特龙", "lang": "CN" }, { "name": "Abiraterone acetate", "lang": "EN" }, { "name": "アビラテロン酢酸エステル", "lang": "JP" } ]

[ { "name": "(3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-ol", "lang": "EN" }, { "name": "17-(3-Pyridyl)androsta-5,16-dien-3beta-ol", "lang": "EN" }, { "name": "Abiraterone acetate (JAN/USP)", "lang": "EN" }, { "name": "abiraterone", "lang": "EN" } ]

[ [ { "name": "Steroid 17-alpha-hydroxylase", "lang": "EN" }, { "name": "类固醇17-α-羟化酶", "lang": "CN" } ] ]

[ [ { "name": "Metastatic Prostate Carcinoma", "lang": "EN" }, { "name": "转移性前列腺癌", "lang": "CN" } ], [ { "name": "Prostate Neuroendocrine Carcinoma", "lang": "EN" }, { "name": "神经内分泌前列腺癌", "lang": "CN" } ], [ { "name": ...

[ "Small molecule drug" ]

Pending

1,303,948,800,000

[ [ { "name": "Metastatic castration-resistant prostate cancer", "lang": "EN" }, { "name": "转移性去势抵抗性前列腺癌", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Australia", "Brazil", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "西罗莫司(白蛋白结合型)", "lang": "CN" }, { "name": "Sirolimus Albumin-Bound", "lang": "EN" } ]

[ { "name": "Nab-Rapamycin", "lang": "EN" }, { "name": "Nab-sirolimus", "lang": "EN" }, { "name": "Nab-西罗莫司", "lang": "CN" }, { "name": "SRL-HSA", "lang": "EN" }, { "name": "Sirolimus Albumin-Bound Nanoparticles", "lang": "EN" }, { "name": "TARZIFYX", ...

[ [ { "name": "Methylmalonyl-CoA Mutase", "lang": "EN" }, { "name": "甲基丙二酰辅酶A变位酶", "lang": "CN" } ], [ { "name": "Serine/threonine-protein kinase mTOR", "lang": "EN" }, { "name": "丝氨酸/苏氨酸蛋白激酶mTOR", "lang": "CN" } ] ]

[ [ { "name": "Perivascular epithelioid cell tumour", "lang": "EN" }, { "name": "血管周围上皮样细胞肿瘤", "lang": "CN" } ], [ { "name": "Hormone receptor positive HER2 negative breast cancer", "lang": "EN" }, { "name": "HR阳性/HER2阴性乳腺癌", "lang": "CN"...

[ "Non-degrading molecular glue" ]

Pending

1,637,539,200,000

[ [ { "name": "Perivascular epithelioid cell tumour", "lang": "EN" }, { "name": "血管周围上皮样细胞肿瘤", "lang": "CN" } ] ]

[ "United States" ]

[ { "name": "信迪利单抗", "lang": "CN" }, { "name": "Sintilimab", "lang": "EN" } ]

[ { "name": "Sintilimab injection", "lang": "EN" }, { "name": "Tyvyt", "lang": "EN" } ]

[ [ { "name": "Programmed cell death protein 1", "lang": "EN" }, { "name": "细胞程序性死亡-1", "lang": "CN" } ] ]

[ [ { "name": "Mismatch repair-deficient Colonic Cancer", "lang": "EN" }, { "name": "错配修复缺陷或微高卫星不稳定性结肠癌", "lang": "CN" } ], [ { "name": "Advanced Endometrial Carcinoma", "lang": "EN" }, { "name": "晚期子宫内膜癌", "lang": "CN" } ], [ ...

[ "Monoclonal antibody" ]

Pending

1,545,609,600,000

[ [ { "name": "Hodgkin's Lymphoma", "lang": "EN" }, { "name": "霍奇金淋巴瘤", "lang": "CN" } ] ]

[ "China", "Macao" ]

[ { "name": "可利霉素", "lang": "CN" }, { "name": "Carrimycin", "lang": "EN" } ]

[ { "name": "Biotechmycin", "lang": "EN" }, { "name": "Biotechspiramycin", "lang": "EN" }, { "name": "Levocarrimycin", "lang": "EN" }, { "name": "bitespiramycin", "lang": "EN" }, { "name": "isovalerylspiramycin", "lang": "EN" }, { "name": "isovalerylspir...

[ [ { "name": "50S ribosomal subunit", "lang": "EN" }, { "name": "50S核糖体亚基", "lang": "CN" } ] ]

[ [ { "name": "Bacterial Infections", "lang": "EN" }, { "name": "细菌感染", "lang": "CN" } ], [ { "name": "Bronchiectasis", "lang": "EN" }, { "name": "支气管扩张", "lang": "CN" } ], [ { "name": "Pseudomonas aeruginosa infection",...

[ "Small molecule drug" ]

Discontinued

1,561,334,400,000

[ [ { "name": "Bacterial Infections", "lang": "EN" }, { "name": "细菌感染", "lang": "CN" } ] ]

[ "China" ]

[ { "name": "布西珠单抗", "lang": "CN" }, { "name": "Brolucizumab-dbll", "lang": "EN" }, { "name": "ブロルシズマブ（遺伝子組換え）", "lang": "JP" } ]

[ { "name": "Brolucizumab (Genetical Recombination)", "lang": "EN" }, { "name": "brolucizumab", "lang": "EN" }, { "name": "布罗鲁珠单抗", "lang": "CN" }, { "name": "溴珠单抗", "lang": "CN" }, { "name": "溴鲁西单抗", "lang": "CN" } ]

[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]

[ [ { "name": "Proliferative retinopathy with diabetes mellitus", "lang": "EN" }, { "name": "伴有糖尿病的增殖性视网膜病变", "lang": "CN" } ], [ { "name": "Choroidal Neovascularization", "lang": "EN" }, { "name": "脉络膜新生血管", "lang": "CN" } ], [ ...

[ "Single-chain FV antibody fragment" ]

Approved

1,570,406,400,000

[ [ { "name": "Wet age-related macular degeneration", "lang": "EN" }, { "name": "湿性年龄相关性黄斑变性", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Canada", "Australia", "Iceland", "South Korea", "Liechtenstein", "Norway" ]

[ { "name": "盐酸羟甲唑啉/马来酸氯苯那敏/甘草酸二钾", "lang": "CN" }, { "name": "Oxymetazoline Hydrochloride/Chlorpheniramine Maleate/Glycyrrhizinate dipotassium", "lang": "EN" } ]

[ { "name": "盐酸羟甲唑啉/马来酸扑尔敏/甘草酸二钾", "lang": "CN" } ]

[ [ { "name": "Corticosteroid 11-beta-dehydrogenase isozyme 1", "lang": "EN" }, { "name": "11β-羟基类固醇脱氢酶-1", "lang": "CN" } ], [ { "name": "Histamine H1 receptor", "lang": "EN" }, { "name": "组胺H1受体", "lang": "CN" } ], [ { ...

[ [ { "name": "Common Cold", "lang": "EN" }, { "name": "普通感冒", "lang": "CN" } ], [ { "name": "Rhinitis, Allergic", "lang": "EN" }, { "name": "过敏性鼻炎", "lang": "CN" } ], [ { "name": "Sinusitis", "lang": "EN" }, ...

[ "Small molecule drug" ]

Approved

1,722,988,800,000

[ [ { "name": "Common Cold", "lang": "EN" }, { "name": "普通感冒", "lang": "CN" } ], [ { "name": "Rhinitis, Allergic", "lang": "EN" }, { "name": "过敏性鼻炎", "lang": "CN" } ], [ { "name": "Sinusitis", "lang": "EN" }, ...

[ "South Korea" ]

[ { "name": "托品卡胺/利多卡因/去氧肾上腺素", "lang": "CN" }, { "name": "Tropicamide/Lidocaine/Phenylephrine", "lang": "EN" } ]

[ { "name": "Fydrane", "lang": "EN" }, { "name": "Lidocaine/phenylephrine/tropicamide", "lang": "EN" }, { "name": "Mydane", "lang": "EN" }, { "name": "Mydrane", "lang": "EN" }, { "name": "Mydricaine", "lang": "EN" } ]

[ [ { "name": "Sodium voltage-gated channel alpha subunits", "lang": "EN" }, { "name": "电压门控钠通道α亚基家族", "lang": "CN" } ], [ { "name": "Muscarinic acetylcholine receptor", "lang": "EN" }, { "name": "毒蕈碱型乙酰胆碱受体家族", "lang": "CN" } ] ]

[ [ { "name": "Miosis", "lang": "EN" }, { "name": "瞳孔缩小", "lang": "CN" } ], [ { "name": "Anesthesia", "lang": "EN" }, { "name": "麻醉", "lang": "CN" } ], [ { "name": "Cataract", "lang": "EN" }, { "name"...

[ "Small molecule drug" ]

Pending

1,466,035,200,000

[ [ { "name": "Anesthesia", "lang": "EN" }, { "name": "麻醉", "lang": "CN" } ] ]

[ "United Kingdom" ]

[ { "name": "甲磺酸仑伐替尼", "lang": "CN" }, { "name": "Lenvatinib mesylate", "lang": "EN" }, { "name": "レンバチニブメシル酸塩", "lang": "JP" } ]

[ { "name": "Lenvatinib mesilate (JAN)", "lang": "EN" }, { "name": "Lenvatinib mesylate (USAN)", "lang": "EN" }, { "name": "lenvatinib", "lang": "EN" }, { "name": "lenvatinib mesilate", "lang": "EN" }, { "name": "甲磺酸乐伐替尼", "lang": "CN" } ]

[ [ { "name": "Fibroblast growth factor receptor 1", "lang": "EN" }, { "name": "成纤维细胞生长因子受体-1", "lang": "CN" } ], [ { "name": "Fibroblast growth factor receptor 2", "lang": "EN" }, { "name": "成纤维细胞生长因子受体-2", "lang": "CN" } ], [ ...

[ [ { "name": "Advanced Endometrial Carcinoma", "lang": "EN" }, { "name": "晚期子宫内膜癌", "lang": "CN" } ], [ { "name": "Recurrent Endometrial Cancer", "lang": "EN" }, { "name": "复发性子宫内膜癌", "lang": "CN" } ], [ { "name": "Thym...

[ "Small molecule drug" ]

Pending

1,423,785,600,000

[ [ { "name": "Thyroid Cancer", "lang": "EN" }, { "name": "甲状腺癌", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "South Korea", "Liechtenstein", "Norway", "Taiwan Province" ]

[ { "name": "盐酸替利洛尔", "lang": "CN" }, { "name": "Tilisolol Hydrochloride", "lang": "EN" } ]

[ { "name": "Daim", "lang": "EN" }, { "name": "Tilisolol", "lang": "EN" }, { "name": "Tilisolol hydrochloride (JAN)", "lang": "EN" } ]

[ [ { "name": "Beta adrenergic receptors", "lang": "EN" }, { "name": "β-肾上腺素能受体家族", "lang": "CN" } ] ]

[ [ { "name": "Hypertension", "lang": "EN" }, { "name": "高血压", "lang": "CN" } ], [ { "name": "Angina Pectoris", "lang": "EN" }, { "name": "心绞痛", "lang": "CN" } ], [ { "name": "Arrhythmias, Cardiac", "lang": "EN" ...

[ "Small molecule drug" ]

Discontinued

800,064,000,000

[ [ { "name": "Angina Pectoris", "lang": "EN" }, { "name": "心绞痛", "lang": "CN" } ] ]

[ "Japan" ]

[ { "name": "乙酰半胱氨酸", "lang": "CN" }, { "name": "Acetylcysteine", "lang": "EN" }, { "name": "アセチルシステイン", "lang": "JP" } ]

[ { "name": "(2R)-2-acetylamino-3-sulfanylpropanoic acid", "lang": "EN" }, { "name": "(R)-2-acetylamino-3-mercaptopropanoic acid", "lang": "EN" }, { "name": "(R)-mercapturic acid", "lang": "EN" }, { "name": "Acetylcysteine (JP17/USP/INN)", "lang": "EN" }, { "name": ...

[ [ { "name": "Free radicals", "lang": "EN" }, { "name": "自由基", "lang": "CN" } ] ]

[ [ { "name": "Bronchiectasis", "lang": "EN" }, { "name": "支气管扩张", "lang": "CN" } ], [ { "name": "Bronchitis", "lang": "EN" }, { "name": "支气管炎", "lang": "CN" } ], [ { "name": "Pulmonary Emphysema", "lang": "EN" ...

[ "Small molecule drug" ]

Discontinued

-198,806,400,000

[ [ { "name": "Chemical and Drug Induced Liver Injury", "lang": "EN" }, { "name": "药物性肝损伤", "lang": "CN" } ], [ { "name": "Liver Injury", "lang": "EN" }, { "name": "肝损伤", "lang": "CN" } ] ]

[ "United States", "China", "Japan", "Australia" ]

[ { "name": "布林西多福韦", "lang": "CN" }, { "name": "Brincidofovir", "lang": "EN" } ]

[ { "name": "BCV", "lang": "EN" }, { "name": "Brincidofovir (USAN)", "lang": "EN" }, { "name": "Cidofovir hexadecyloxypropyl ester", "lang": "EN" }, { "name": "HDP-CDV", "lang": "EN" }, { "name": "HDP-cidofovir", "lang": "EN" }, { "name": "Hexadecyl-oxyp...

[ [ { "name": "Human herpesvirus 1 DNA polymerase", "lang": "EN" }, { "name": "人单纯疱疹病毒1型DNA聚合酶", "lang": "CN" } ], [ { "name": "Human herpesvirus 5 DNA polymerase", "lang": "EN" }, { "name": "人单纯疱疹病毒5型DNA聚合酶", "lang": "CN" } ] ]

[ [ { "name": "Smallpox", "lang": "EN" }, { "name": "天花", "lang": "CN" } ], [ { "name": "Adenovirus Infections, Human", "lang": "EN" }, { "name": "腺病毒感染", "lang": "CN" } ], [ { "name": "Leukoencephalopathy, Progressive M...

[ "Small molecule drug" ]

Discontinued

1,622,764,800,000

[ [ { "name": "Smallpox", "lang": "EN" }, { "name": "天花", "lang": "CN" } ] ]

[ "United States", "Canada" ]

[ { "name": "康柏西普", "lang": "CN" }, { "name": "Conbercept", "lang": "EN" } ]

[ { "name": "Conbercept Ophthalmic", "lang": "EN" }, { "name": "Lumitin", "lang": "EN" }, { "name": "Recombinant human VEGF receptor-Fc fusion protein", "lang": "EN" }, { "name": "重组人血管内皮生长因子受体-抗体融合蛋白（成都市康弘生物）", "lang": "CN" } ]

[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]

[ [ { "name": "Retinal vein occlusion-related macular edema", "lang": "EN" }, { "name": "视网膜静脉阻塞相关黄斑水肿", "lang": "CN" } ], [ { "name": "Diabetic macular oedema", "lang": "EN" }, { "name": "糖尿病性黄斑水肿", "lang": "CN" } ], [ { ...

[ "Fc fusion protein" ]

Pending

1,385,510,400,000

[ [ { "name": "Wet age-related macular degeneration", "lang": "EN" }, { "name": "湿性年龄相关性黄斑变性", "lang": "CN" } ] ]

[ "China" ]

[ { "name": "艾司奥美拉唑镁/碳酸氢钠", "lang": "CN" }, { "name": "Esomeprazole Magnesium/Sodium Bicarbonate", "lang": "EN" } ]

[ { "name": "埃索美拉唑镁/碳酸氢钠", "lang": "CN" }, { "name": "奥美拉唑镁碳酸氢钠", "lang": "CN" } ]

[ [ { "name": "Proton pump", "lang": "EN" }, { "name": "质子泵", "lang": "CN" } ] ]

[ [ { "name": "Hyperchlorhydria", "lang": "EN" }, { "name": "胃酸过多", "lang": "CN" } ], [ { "name": "Duodenal Ulcer", "lang": "EN" }, { "name": "十二指肠溃疡", "lang": "CN" } ], [ { "name": "Erosive esophagitis", "lang": "...

[ "Small molecule drug" ]

IND Approval

1,525,046,400,000

[ [ { "name": "Gastroesophageal Reflux", "lang": "EN" }, { "name": "胃食管反流", "lang": "CN" } ] ]

[ "China", "South Korea" ]

[ { "name": "甲酪氨酸", "lang": "CN" }, { "name": "Metyrosine", "lang": "EN" }, { "name": "メチロシン", "lang": "JP" } ]

[ { "name": "(-)-alpha-Methyl-L-tyrosine", "lang": "EN" }, { "name": "(-)-α-methyl-L-tyrosine", "lang": "EN" }, { "name": "(S)-alpha-Methyltyrosine", "lang": "EN" }, { "name": "(–)-α-methyl-L-tyrosine", "lang": "EN" }, { "name": "AMPT", "lang": "EN" }, { ...

[ [ { "name": "Tyrosine 3-hydroxylase", "lang": "EN" }, { "name": "酪氨酸-3-羟化酶", "lang": "CN" } ] ]

[ [ { "name": "Pheochromocytoma", "lang": "EN" }, { "name": "嗜铬细胞瘤", "lang": "CN" } ], [ { "name": "Bipolar Disorder", "lang": "EN" }, { "name": "躁郁症", "lang": "CN" } ], [ { "name": "DiGeorge Syndrome", "lang": "EN...

[ "Small molecule drug" ]

Discontinued

307,756,800,000

[ [ { "name": "Pheochromocytoma", "lang": "EN" }, { "name": "嗜铬细胞瘤", "lang": "CN" } ] ]

[ "United States", "Japan" ]

[ { "name": "马来酸氯苯那敏/氢溴酸东莨菪碱水合物/无水咖啡因/烟酰胺/盐酸吡哆醇", "lang": "CN" }, { "name": "Chlorpheniramine Maleate/Scopolamine Hydrobromide Hydrate/Anhydrous Caffeine/Nicotinamide/Pyridoxine Hydrochloride", "lang": "EN" } ]

null

[ [ { "name": "Adenosine A2a receptor", "lang": "EN" }, { "name": "腺苷A2a受体", "lang": "CN" } ], [ { "name": "Poly (ADP-Ribose) polymerase 1", "lang": "EN" }, { "name": "聚腺苷二磷酸核糖聚合酶1", "lang": "CN" } ], [ { "name": "Histam...

[ [ { "name": "Motion Sickness", "lang": "EN" }, { "name": "晕动病", "lang": "CN" } ] ]

[ "Small molecule drug" ]

Approved

1,753,660,800,000

[ [ { "name": "Motion Sickness", "lang": "EN" }, { "name": "晕动病", "lang": "CN" } ] ]

[ "South Korea" ]

[ { "name": "德曲妥珠单抗", "lang": "CN" }, { "name": "Fam-trastuzumab deruxtecan-NXKI", "lang": "EN" }, { "name": "トラスツズマブデルクステカン（遺伝子組換え）", "lang": "JP" } ]

[ { "name": "Fam-trastuzumab deruxtecan", "lang": "EN" }, { "name": "T-DXd", "lang": "EN" }, { "name": "Trastuzumab Deruxtecan (Genetical Recombination)", "lang": "EN" }, { "name": "Trastuzumab deruxtecan", "lang": "EN" }, { "name": "德喜曲妥珠单抗", "lang": "CN" }, ...

[ [ { "name": "Receptor tyrosine-protein kinase erbB-2", "lang": "EN" }, { "name": "受体蛋白酪氨酸激酶 erbB-2", "lang": "CN" } ], [ { "name": "DNA topoisomerase I", "lang": "EN" }, { "name": "DNA拓扑异构酶I", "lang": "CN" } ] ]

[ [ { "name": "Stomach Cancer", "lang": "EN" }, { "name": "胃癌", "lang": "CN" } ], [ { "name": "HER2 Positive Solid Tumors", "lang": "EN" }, { "name": "HER2阳性实体瘤", "lang": "CN" } ], [ { "name": "HR-positive/HER2-low Breas...

[ "Antibody drug conjugate (ADC)" ]

Approved

1,576,800,000,000

[ [ { "name": "HER2 Positive Breast Cancer", "lang": "EN" }, { "name": "HER2阳性乳腺癌", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "United Kingdom", "Canada", "Australia", "India", "Israel", "Iceland", "South Korea", "Liechtenstein", "Norway" ]

[ { "name": "艾普拉唑钠", "lang": "CN" }, { "name": "Sodium ilaprazole", "lang": "EN" } ]

null

[ [ { "name": "Proton pump", "lang": "EN" }, { "name": "质子泵", "lang": "CN" } ] ]

[ [ { "name": "Peptic Ulcer Hemorrhage", "lang": "EN" }, { "name": "消化性溃疡出血", "lang": "CN" } ], [ { "name": "Hemorrhage", "lang": "EN" }, { "name": "出血", "lang": "CN" } ], [ { "name": "Peptic Ulcer", "lang": "EN" ...

[ "Small molecule drug" ]

Phase 3 Clinical

1,514,419,200,000

[ [ { "name": "Peptic Ulcer Hemorrhage", "lang": "EN" }, { "name": "消化性溃疡出血", "lang": "CN" } ] ]

[ "China", "Indonesia" ]

[ { "name": "贝伐珠单抗生物类似药（Curateq）", "lang": "CN" }, { "name": "Bevacizumab Biosimilar (CuraTeQ)", "lang": "EN" } ]

[ { "name": "Bevacizumab Biosimilar (Curateq Biologics Pvt Ltd.)", "lang": "EN" }, { "name": "贝伐珠单抗生物类似药（Curateq Biologics Pvt Ltd.）", "lang": "CN" } ]

[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]

[ [ { "name": "Advanced Renal Cell Carcinoma", "lang": "EN" }, { "name": "晚期肾细胞癌", "lang": "CN" } ], [ { "name": "EGFR positive Non-squamous non-small cell lung cancer", "lang": "EN" }, { "name": "EGFR阳性非鳞状非小细胞肺癌", "lang": "CN" } ],...

[ "Biosimilar", "Monoclonal antibody" ]

Approved

1,734,652,800,000

[ [ { "name": "Advanced Renal Cell Carcinoma", "lang": "EN" }, { "name": "晚期肾细胞癌", "lang": "CN" } ], [ { "name": "EGFR positive Non-squamous non-small cell lung cancer", "lang": "EN" }, { "name": "EGFR阳性非鳞状非小细胞肺癌", "lang": "CN" } ],...

[ "United Kingdom" ]

[ { "name": "福莫司汀", "lang": "CN" }, { "name": "Fotemustine", "lang": "EN" } ]

[ { "name": "(+-)-Diethyl (1-(3-(2-chloroethyl)-3-nitrosoureido)ethyl)phosphonate", "lang": "EN" }, { "name": "Diethyl-1-(3-(2-chloroethyl)-3-nitrosoureido)ethylphosphonate", "lang": "EN" }, { "name": "Fotemustine (INN/BAN)", "lang": "EN" }, { "name": "Muforan", "lang": "EN...

[ [ { "name": "DNA", "lang": "EN" }, { "name": "DNA", "lang": "CN" } ] ]

[ [ { "name": "Brain Cancer", "lang": "EN" }, { "name": "脑癌", "lang": "CN" } ], [ { "name": "Melanoma", "lang": "EN" }, { "name": "黑色素瘤", "lang": "CN" } ], [ { "name": "metastatic non-small cell lung cancer", "lang...

[ "Small molecule drug" ]

Pending

625,881,600,000

[ [ { "name": "Brain Cancer", "lang": "EN" }, { "name": "脑癌", "lang": "CN" } ], [ { "name": "Melanoma", "lang": "EN" }, { "name": "黑色素瘤", "lang": "CN" } ] ]

[ "China", "France" ]

[ { "name": "氯替泼诺妥布霉素", "lang": "CN" }, { "name": "Loteprednol Etabonate/Tobramycin", "lang": "EN" } ]

[ { "name": "LE-T", "lang": "EN" }, { "name": "LE-Tobramycin", "lang": "EN" }, { "name": "Loteprednol Etabonate and Tobramycin", "lang": "EN" }, { "name": "Tobramycin/loteprednol etabonate", "lang": "EN" }, { "name": "Zylet", "lang": "EN" }, { "name": "氯...

[ [ { "name": "30S ribosomal subunit", "lang": "EN" }, { "name": "30S核糖体亚基", "lang": "CN" } ], [ { "name": "Glucocorticoid receptor", "lang": "EN" }, { "name": "糖皮质激素受体", "lang": "CN" } ], [ { "name": "Cytosolic phosphol...

[ [ { "name": "Ocular inflammation", "lang": "EN" }, { "name": "眼部炎症", "lang": "CN" } ], [ { "name": "Blepharitis", "lang": "EN" }, { "name": "睑缘炎", "lang": "CN" } ], [ { "name": "Blepharokeratoconjunctivitis", "la...

[ "Small molecule drug" ]

Pending

1,102,982,400,000

[ [ { "name": "Ocular inflammation", "lang": "EN" }, { "name": "眼部炎症", "lang": "CN" } ] ]

[ "United States", "China" ]

[ { "name": "甲基卡泰司特", "lang": "CN" }, { "name": "Carotegrast methyl", "lang": "EN" }, { "name": "カロテグラストメチル", "lang": "JP" } ]

[ { "name": "Carotegrast", "lang": "EN" }, { "name": "Carotegrast methyl (JAN)", "lang": "EN" } ]

[ [ { "name": "Integrin alpha-4/beta-1", "lang": "EN" }, { "name": "整合素α-4/β-1复合体", "lang": "CN" } ], [ { "name": "Integrin alpha-4/beta-7", "lang": "EN" }, { "name": "整合素α-4/β-7复合体", "lang": "CN" } ] ]

[ [ { "name": "Colitis, Ulcerative", "lang": "EN" }, { "name": "溃疡性结肠炎", "lang": "CN" } ] ]

[ "Small molecule drug" ]

Approved

1,648,425,600,000

[ [ { "name": "Colitis, Ulcerative", "lang": "EN" }, { "name": "溃疡性结肠炎", "lang": "CN" } ] ]

[ "Japan" ]

[ { "name": "促皮质素", "lang": "CN" }, { "name": "Corticotropin", "lang": "EN" } ]

[ { "name": "ACTH", "lang": "EN" }, { "name": "Adrenocorticotrophin", "lang": "EN" }, { "name": "Adrenocorticotropic hormone", "lang": "EN" }, { "name": "CORTICOTROPIN-ZINC HYDROXIDE", "lang": "EN" }, { "name": "Corticotrophin", "lang": "EN" }, { "name":...

[ [ { "name": "Melanocortin receptor", "lang": "EN" }, { "name": "黑皮质素受体", "lang": "CN" } ] ]

[ [ { "name": "Choroiditis", "lang": "EN" }, { "name": "脉络膜炎", "lang": "CN" } ], [ { "name": "Iridocyclitis", "lang": "EN" }, { "name": "虹膜睫状体炎", "lang": "CN" } ], [ { "name": "Iritis", "lang": "EN" }, { ...

[ "Synthetic peptide" ]

Pending

-615,340,800,000

[ [ { "name": "Arthritis, Psoriatic", "lang": "EN" }, { "name": "银屑病关节炎", "lang": "CN" } ], [ { "name": "Dermatomyositis", "lang": "EN" }, { "name": "皮肌炎", "lang": "CN" } ], [ { "name": "Edema", "lang": "EN" },...

[ "United States" ]

[ { "name": "托珠单抗生物类似药（丽珠）", "lang": "CN" }, { "name": "Tocilizumab biosimilar (Livzon)", "lang": "EN" } ]

[ { "name": "重组人源化抗人IL-6R单克隆抗体", "lang": "CN" } ]

[ [ { "name": "Interleukin-6 receptor alpha subunit", "lang": "EN" }, { "name": "白细胞介素-6受体α亚基", "lang": "CN" } ] ]

[ [ { "name": "Rheumatoid Arthritis", "lang": "EN" }, { "name": "类风湿关节炎", "lang": "CN" } ] ]

[ "Biosimilar", "Monoclonal antibody" ]

Approved

1,674,000,000,000

[ [ { "name": "Rheumatoid Arthritis", "lang": "EN" }, { "name": "类风湿关节炎", "lang": "CN" } ] ]

[ "China" ]

[ { "name": "枸橼酸托瑞米芬", "lang": "CN" }, { "name": "Toremifene Citrate", "lang": "EN" }, { "name": "トレミフェンクエン酸塩", "lang": "JP" } ]

[ { "name": "Acapodene", "lang": "EN" }, { "name": "Toremifene citrate (JAN/USAN)", "lang": "EN" }, { "name": "toremifene", "lang": "EN" }, { "name": "托瑞米芬", "lang": "CN" } ]

[ [ { "name": "Estrogen receptors", "lang": "EN" }, { "name": "雌激素受体家族", "lang": "CN" } ] ]

[ [ { "name": "Estrogen receptor-negative breast cancer", "lang": "EN" }, { "name": "ER阴性乳腺癌", "lang": "CN" } ], [ { "name": "Metastatic breast cancer", "lang": "EN" }, { "name": "转移性乳腺癌", "lang": "CN" } ], [ { "name": "...

[ "Small molecule drug" ]

Preclinical

796,608,000,000

[ [ { "name": "Breast Cancer", "lang": "EN" }, { "name": "乳腺癌", "lang": "CN" } ] ]

[ "China", "European Union", "Japan", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "尼古丁", "lang": "CN" }, { "name": "Nicotine", "lang": "EN" } ]

[ { "name": "(S)-(−)-nicotine", "lang": "EN" }, { "name": "(S)-3-(1-methylpyrrolidin-2-yl)pyridine", "lang": "EN" }, { "name": "(S)-3-(N-methylpyrrolidin-2-yl)pyridine", "lang": "EN" }, { "name": "(S)-Nicotine", "lang": "EN" }, { "name": "(−)-nicotine", "lang": ...

[ [ { "name": "Muscle-type nicotinic acetylcholine receptor", "lang": "EN" }, { "name": "肌肉型烟碱乙酰胆碱受体复合体", "lang": "CN" } ] ]

[ [ { "name": "Smoking Cessation", "lang": "EN" }, { "name": "尼古丁成瘾", "lang": "CN" } ], [ { "name": "Tobacco Use Disorder", "lang": "EN" }, { "name": "烟草依赖", "lang": "CN" } ], [ { "name": "Nicotine Dependence", "la...

[ "Small molecule drug" ]

Early Phase 1

442,800,000,000

[ [ { "name": "Nicotine Dependence", "lang": "EN" }, { "name": "尼古丁依赖", "lang": "CN" } ] ]

[ "United States", "China", "Japan", "Australia", "South Korea" ]

[ { "name": "盐酸芬戈莫德", "lang": "CN" }, { "name": "Fingolimod Hydrochloride", "lang": "EN" }, { "name": "フィンゴリモド塩酸塩", "lang": "JP" } ]

[ { "name": "FINGOLIMOD", "lang": "EN" }, { "name": "Fingolimod hydrochloride (JAN/USAN)", "lang": "EN" }, { "name": "Gilenia", "lang": "EN" } ]

[ [ { "name": "Sphingosine 1-phosphate receptor Edg-1", "lang": "EN" }, { "name": "鞘氨醇-1-磷酸受体-Edg-1", "lang": "CN" } ], [ { "name": "Sphingosine 1-phosphate receptor Edg-3", "lang": "EN" }, { "name": "鞘氨醇-1-磷酸受体-Edg-3", "lang": "CN" }...

[ [ { "name": "Multiple Sclerosis, Relapsing-Remitting", "lang": "EN" }, { "name": "复发-缓解型多发性硬化", "lang": "CN" } ], [ { "name": "Multiple Sclerosis", "lang": "EN" }, { "name": "多发性硬化症", "lang": "CN" } ], [ { "name": "Mul...

[ "Small molecule drug" ]

Preclinical

1,285,027,200,000

[ [ { "name": "Multiple sclerosis relapse", "lang": "EN" }, { "name": "复发性多发性硬化", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "South Korea", "Liechtenstein", "Norway" ]

[ { "name": "利那洛肽", "lang": "CN" }, { "name": "Linaclotide", "lang": "EN" }, { "name": "リナクロチド", "lang": "JP" } ]

[ { "name": "Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr (disulfide bridge: 1-6; 2-10; 5-13)", "lang": "EN" }, { "name": "Linaclotide (JAN/USAN)", "lang": "EN" }, { "name": "Linaclotide acetate", "lang": "EN" } ]

[ [ { "name": "Heat-stable enterotoxin receptor", "lang": "EN" }, { "name": "热稳定肠毒素受体", "lang": "CN" } ], [ { "name": "Soluble guanylate cyclase", "lang": "EN" }, { "name": "可溶性鸟苷酸环化酶复合体", "lang": "CN" } ] ]

[ [ { "name": "Constipation - functional", "lang": "EN" }, { "name": "功能性便秘", "lang": "CN" } ], [ { "name": "Chronic constipation", "lang": "EN" }, { "name": "慢性便秘", "lang": "CN" } ], [ { "name": "Chronic idiopathic cons...

[ "Synthetic peptide", "Cyclic Peptide" ]

Pending

1,346,284,800,000

[ [ { "name": "Chronic idiopathic constipation", "lang": "EN" }, { "name": "慢性特发性便秘", "lang": "CN" } ], [ { "name": "Irritable bowel syndrome with constipation", "lang": "EN" }, { "name": "便秘型肠易激综合征", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "United Kingdom", "Canada", "Australia", "Switzerland", "Iceland", "Liechtenstein", "Mexico", "Norway" ]

[ { "name": "溴美喷酯", "lang": "CN" }, { "name": "Mepenzolate Bromide", "lang": "EN" }, { "name": "メペンゾラート臭化物", "lang": "JP" } ]

[ { "name": "Mepenzolate bromide (JP17/INN)", "lang": "EN" } ]

[ [ { "name": "Muscarinic acetylcholine receptor", "lang": "EN" }, { "name": "毒蕈碱型乙酰胆碱受体家族", "lang": "CN" } ] ]

[ [ { "name": "Irritable Bowel Syndrome", "lang": "EN" }, { "name": "肠易激综合征", "lang": "CN" } ], [ { "name": "Peptic Ulcer", "lang": "EN" }, { "name": "消化性溃疡", "lang": "CN" } ] ]

[ "Small molecule drug" ]

Withdrawn

-414,374,400,000

[ [ { "name": "Peptic Ulcer", "lang": "EN" }, { "name": "消化性溃疡", "lang": "CN" } ] ]

[ "Japan" ]

[ { "name": "尼卡利单抗", "lang": "CN" }, { "name": "Nipocalimab-aahu", "lang": "EN" }, { "name": "ニポカリマブ（遺伝子組換え）", "lang": "JP" } ]

[ { "name": "Immunoglobulin g1, anti-(human neonatal fc receptor) (human monoclonal m281 .gamma.-1 chain), disulfide with human monoclonal m281 .lambda.-chain, dimer", "lang": "EN" }, { "name": "Nipocalimab (USAN)", "lang": "EN" }, { "name": "anti-FcRn monoclonal antibody(Momenta Pharmaceu...

[ [ { "name": "IgG receptor FcRn large subunit p51", "lang": "EN" }, { "name": "IgG受体FcRn大亚基p51", "lang": "CN" } ] ]

[ [ { "name": "Myasthenia Gravis", "lang": "EN" }, { "name": "重症肌无力", "lang": "CN" } ], [ { "name": "Warm autoimmune hemolytic anemia", "lang": "EN" }, { "name": "温热型自身免疫性溶血性贫血", "lang": "CN" } ], [ { "name": "Systemic L...

[ "Monoclonal antibody" ]

Phase 2/3 Clinical

1,745,884,800,000

[ [ { "name": "Myasthenia Gravis", "lang": "EN" }, { "name": "重症肌无力", "lang": "CN" } ] ]

[ "United States", "European Union", "Japan", "Canada", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "盐酸氮卓斯汀", "lang": "CN" }, { "name": "Azelastine Hydrochloride", "lang": "EN" }, { "name": "アゼラスチン塩酸塩", "lang": "JP" } ]

[ { "name": "4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone", "lang": "EN" }, { "name": "Afluon", "lang": "EN" }, { "name": "Allergodil", "lang": "EN" }, { "name": "Astepro", "lang": "EN" }, { "name": "Astepro Once-Daily", "lang": ...

[ [ { "name": "Histamine H1 receptor", "lang": "EN" }, { "name": "组胺H1受体", "lang": "CN" } ] ]

[ [ { "name": "Respiratory Tract Infections", "lang": "EN" }, { "name": "呼吸道感染", "lang": "CN" } ], [ { "name": "Rhinitis, Allergic, Perennial", "lang": "EN" }, { "name": "常年性变应性鼻炎", "lang": "CN" } ], [ { "name": "Rhiniti...

[ "Small molecule drug" ]

Withdrawn

515,203,200,000

[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ], [ { "name": "Rhinitis, Allergic", "lang": "EN" }, { "name": "过敏性鼻炎", "lang": "CN" } ] ]

[ "United States", "China", "Japan", "Australia" ]

[ { "name": "雷珠单抗生物类似药(Formycon AG)", "lang": "CN" }, { "name": "Ranibizumab biosimilar(Formycon AG)", "lang": "EN" } ]

[ { "name": "RANIBIZUMAB-EQRN", "lang": "EN" }, { "name": "Ranibizumab Biosimilar (Formycon AG)", "lang": "EN" }, { "name": "Ranibizumab-leyk", "lang": "EN" }, { "name": "雷珠单抗生物类似药（Formycon AG）", "lang": "CN" } ]

[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]

[ [ { "name": "Choroidal Neovascularization", "lang": "EN" }, { "name": "脉络膜新生血管", "lang": "CN" } ], [ { "name": "Diabetic macular oedema", "lang": "EN" }, { "name": "糖尿病性黄斑水肿", "lang": "CN" } ], [ { "name": "Diabetic Re...

[ "Fab fragment", "Biosimilar" ]

Approved

1,652,745,600,000

[ [ { "name": "Dystrophy, Macular", "lang": "EN" }, { "name": "黄斑变性", "lang": "CN" } ] ]

[ "United States", "United Kingdom" ]

[ { "name": "重酒石酸肾上腺素", "lang": "CN" }, { "name": "Epinephrine Bitartrate", "lang": "EN" } ]

[ { "name": "Epinephrine bitartrate (JAN/USP)", "lang": "EN" }, { "name": "酒石酸肾上腺素", "lang": "CN" } ]

[ [ { "name": "Adrenergic receptor alpha-1", "lang": "EN" }, { "name": "肾上腺素能受体α-1家族", "lang": "CN" } ], [ { "name": "Beta adrenergic receptors", "lang": "EN" }, { "name": "β-肾上腺素能受体家族", "lang": "CN" } ] ]

[ [ { "name": "Hypersensitivity", "lang": "EN" }, { "name": "超敏反应", "lang": "CN" } ], [ { "name": "Shock, Septic", "lang": "EN" }, { "name": "脓毒性休克", "lang": "CN" } ], [ { "name": "Hypotension", "lang": "EN" },...

[ "Small molecule drug" ]

Pending

-435,974,400,000

[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ] ]

[ "United States" ]

[ { "name": "利拉鲁肽", "lang": "CN" }, { "name": "Liraglutide", "lang": "EN" }, { "name": "リラグルチド（遺伝子組換え）", "lang": "JP" } ]

[ { "name": "Liraglutide (Genetical Recombination)", "lang": "EN" }, { "name": "Liraglutide Recombinant", "lang": "EN" }, { "name": "Saxenda", "lang": "EN" } ]

[ [ { "name": "Glucagon-like peptide 1 receptor", "lang": "EN" }, { "name": "胰高血糖素样肽-1受体", "lang": "CN" } ] ]

[ [ { "name": "Obesity", "lang": "EN" }, { "name": "肥胖", "lang": "CN" } ], [ { "name": "Overweight", "lang": "EN" }, { "name": "超重", "lang": "CN" } ], [ { "name": "Diabetes Mellitus, Type 2", "lang": "EN" }, ...

[ "Recombinant polypeptide" ]

Discontinued

1,246,320,000,000

[ [ { "name": "Diabetes Mellitus, Type 2", "lang": "EN" }, { "name": "2型糖尿病", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Canada", "Australia", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "卡妥索单抗", "lang": "CN" }, { "name": "Catumaxomab", "lang": "EN" } ]

[ { "name": "Anti-CD3 anti-EpCAM monoclonal antibody", "lang": "EN" }, { "name": "Anti-EpCAM anti-CD3 monoclonal antibody", "lang": "EN" }, { "name": "Catumaxomab (INN)", "lang": "EN" }, { "name": "catumaxomab", "lang": "EN" } ]

[ [ { "name": "T cell surface glycoprotein CD3", "lang": "EN" }, { "name": "T细胞表面糖蛋白CD3复合体", "lang": "CN" } ], [ { "name": "Epithelial cell adhesion molecule", "lang": "EN" }, { "name": "上皮细胞粘附分子", "lang": "CN" } ] ]

[ [ { "name": "EpCAM positive Solid Tumors", "lang": "EN" }, { "name": "EpCAM阳性实体瘤", "lang": "CN" } ], [ { "name": "Malignant ascites", "lang": "EN" }, { "name": "恶性腹水", "lang": "CN" } ], [ { "name": "Advanced gastric ca...

[ "Bispecific T-cell Engager (BiTE)" ]

Pending

1,240,185,600,000

[ [ { "name": "Malignant ascites", "lang": "EN" }, { "name": "恶性腹水", "lang": "CN" } ] ]

[ "European Union", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "依来沙多/依伐卡托/替扎卡托", "lang": "CN" }, { "name": "Elexacaftor/Ivacaftor/Tezacaftor", "lang": "EN" } ]

[ { "name": "ELX/TEZ/IVA", "lang": "EN" }, { "name": "Elexacaftor/ivacaftor/tezacaftor + ivacaftor", "lang": "EN" }, { "name": "Ivacaftor/tezacaftor/VX 445", "lang": "EN" }, { "name": "TRIKAFTA", "lang": "EN" }, { "name": "Tezacaftor/VX-445/ivacaftor", "lang": "...

[ [ { "name": "Cystic fibrosis transmembrane conductance regulator", "lang": "EN" }, { "name": "囊性纤维化跨膜传导调节因子", "lang": "CN" } ], [ { "name": "P-glycoprotein 1", "lang": "EN" }, { "name": "P-糖蛋白-1", "lang": "CN" } ] ]

[ [ { "name": "Cystic Fibrosis", "lang": "EN" }, { "name": "囊性纤维化", "lang": "CN" } ], [ { "name": "Cough", "lang": "EN" }, { "name": "咳嗽", "lang": "CN" } ], [ { "name": "Cystic fibrosis related diabetes", "lang": "...

[ "Small molecule drug" ]

Pending

1,571,616,000,000

[ [ { "name": "Cystic Fibrosis", "lang": "EN" }, { "name": "囊性纤维化", "lang": "CN" } ] ]

[ "United States", "European Union", "Canada", "Australia", "Switzerland", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "呼吸道合胞病毒疫苗（辉瑞大药厂）", "lang": "CN" }, { "name": "RSVpreF", "lang": "EN" } ]

[ { "name": "Respiratory Syncytial Virus Vaccine", "lang": "EN" }, { "name": "recombinant respiratory syncytial virus pre-fusion F protein, water for injections(Pfizer)", "lang": "EN" } ]

[ [ { "name": "Respiratory syncytial virus F protein", "lang": "EN" }, { "name": "呼吸道合胞病毒F蛋白", "lang": "CN" } ] ]

[ [ { "name": "Pneumonia due to respiratory syncytial virus", "lang": "EN" }, { "name": "呼吸道合胞病毒肺炎", "lang": "CN" } ], [ { "name": "Respiratory Syncytial Virus Infections", "lang": "EN" }, { "name": "呼吸道合胞体病毒感染", "lang": "CN" } ], ...

[ "Prophylactic vaccine" ]

Approved

1,672,790,400,000

[ [ { "name": "Lower Respiratory Tract Infections", "lang": "EN" }, { "name": "下呼吸道感染", "lang": "CN" } ] ]

[ "United States", "European Union", "Japan", "United Kingdom", "Canada", "Australia", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "曲尼司特", "lang": "CN" }, { "name": "Tranilast", "lang": "EN" }, { "name": "トラニラスト", "lang": "JP" } ]

[ { "name": "N-(3,4-Dimethoxycinnamoyl)anthranilic acid", "lang": "EN" }, { "name": "Tranilast (JP17/USAN/INN)", "lang": "EN" } ]

[ [ { "name": "Transforming growth factor beta", "lang": "EN" }, { "name": "转化生长因子β", "lang": "CN" } ] ]

[ [ { "name": "Conjunctivitis, Allergic", "lang": "EN" }, { "name": "变应性结膜炎", "lang": "CN" } ], [ { "name": "Idiopathic Pulmonary Fibrosis", "lang": "EN" }, { "name": "特发性肺纤维化", "lang": "CN" } ], [ { "name": "Corneal Dys...

[ "Small molecule drug" ]

Phase 1 Clinical

392,947,200,000

[ [ { "name": "Asthma", "lang": "EN" }, { "name": "哮喘", "lang": "CN" } ] ]

[ "Japan" ]

[ { "name": "胰酶/纤维素酶/熊去氧胆酸/聚二甲基硅氧烷", "lang": "CN" }, { "name": "Pancreatin/Cellulase/Ursodeoxycholic Acid/Dimethicone", "lang": "EN" } ]

null

[ [ { "name": "Bile acid receptor FXR", "lang": "EN" }, { "name": "胆汁酸受体FXR", "lang": "CN" } ] ]

[ [ { "name": "Dyspepsia", "lang": "EN" }, { "name": "消化不良", "lang": "CN" } ] ]

[ "Enzyme" ]

Approved

1,751,932,800,000

[ [ { "name": "Dyspepsia", "lang": "EN" }, { "name": "消化不良", "lang": "CN" } ] ]

[ "South Korea" ]

[ { "name": "沙利鲁单抗", "lang": "CN" }, { "name": "Sarilumab", "lang": "EN" }, { "name": "サリルマブ（遺伝子組換え）", "lang": "JP" } ]

[ { "name": "Anti-IL 6 receptor antibody", "lang": "EN" }, { "name": "Anti-interleukin 6 receptor antibody", "lang": "EN" }, { "name": "Sarilumab (Genetical Recombination)", "lang": "EN" }, { "name": "Sarilumab (USAN)", "lang": "EN" }, { "name": "Sarilumab (genetica...

[ [ { "name": "Interleukin-6 receptor alpha subunit", "lang": "EN" }, { "name": "白细胞介素-6受体α亚基", "lang": "CN" } ] ]

[ [ { "name": "Polyarticular Juvenile Idiopathic Arthritis", "lang": "EN" }, { "name": "多关节型幼年特发性关节炎", "lang": "CN" } ], [ { "name": "Polymyalgia Rheumatica", "lang": "EN" }, { "name": "风湿性多肌痛", "lang": "CN" } ], [ { "na...

[ "Monoclonal antibody" ]

Phase 2 Clinical

1,484,179,200,000

[ [ { "name": "Rheumatoid Arthritis", "lang": "EN" }, { "name": "类风湿关节炎", "lang": "CN" } ] ]

[ "United States", "European Union", "Japan", "Canada", "Australia", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "阿司匹林/富马酸伏诺拉生", "lang": "CN" }, { "name": "Aspirin/Vonoprazan Fumarate", "lang": "EN" }, { "name": "アスピリン/ボノプラザンフマル酸塩", "lang": "JP" } ]

[ { "name": "TAK-438/Aspirin", "lang": "EN" }, { "name": "伏诺拉生/阿司匹林", "lang": "CN" } ]

[ [ { "name": "Cyclooxygenases", "lang": "EN" }, { "name": "环氧化酶", "lang": "CN" } ], [ { "name": "Potassium-transporting ATPase", "lang": "EN" }, { "name": "钾离子转运ATP酶复合体", "lang": "CN" } ], [ { "name": "Proton pump", ...

[ [ { "name": "Angina Pectoris", "lang": "EN" }, { "name": "心绞痛", "lang": "CN" } ], [ { "name": "Thromboembolism", "lang": "EN" }, { "name": "血栓栓塞", "lang": "CN" } ] ]

[ "Small molecule drug" ]

Approved

1,585,094,400,000

[ [ { "name": "Angina Pectoris", "lang": "EN" }, { "name": "心绞痛", "lang": "CN" } ], [ { "name": "Thromboembolism", "lang": "EN" }, { "name": "血栓栓塞", "lang": "CN" } ] ]

[ "Japan" ]

[ { "name": "非格司亭生物类似药 (泰福生技)", "lang": "CN" }, { "name": "Filgrastim-txid", "lang": "EN" } ]

[ { "name": "Filgrastim Biosimilar (Tanvex BioPharma, Inc.)", "lang": "EN" }, { "name": "非格司亭生物类似药（Tanvex BioPharma, Inc.）", "lang": "CN" } ]

[ [ { "name": "Colony stimulating factor 3 receptor", "lang": "EN" }, { "name": "巨噬细胞集落刺激因子3受体", "lang": "CN" } ] ]

[ [ { "name": "Febrile Neutropenia", "lang": "EN" }, { "name": "粒细胞减少性发热", "lang": "CN" } ], [ { "name": "Stem cell mobilisation", "lang": "EN" }, { "name": "干细胞动员", "lang": "CN" } ], [ { "name": "Neutropenia", "la...

[ "Biosimilar", "Colony-stimulating factors" ]

Approved

1,633,046,400,000

[ [ { "name": "Neutropenia", "lang": "EN" }, { "name": "中性粒细胞减少", "lang": "CN" } ] ]

[ "United States", "Canada" ]

[ { "name": "A型肉毒毒素 (Medytox)", "lang": "CN" }, { "name": "Botulinum toxin A(Medytox)", "lang": "EN" } ]

[ { "name": "Botulift", "lang": "EN" }, { "name": "Botulinum toxin A", "lang": "EN" }, { "name": "Cunox", "lang": "EN" }, { "name": "Innotox", "lang": "EN" }, { "name": "KbtxA", "lang": "EN" }, { "name": "Liquid-type botulinum toxin type A", "lang": ...

[ [ { "name": "Synaptosomal-associated protein 25", "lang": "EN" }, { "name": "突触相关蛋白25", "lang": "CN" } ] ]

[ [ { "name": "Benign Essential Blepharospasm", "lang": "EN" }, { "name": "良性基础型眼睑痉挛", "lang": "CN" } ], [ { "name": "Foot Deformities", "lang": "EN" }, { "name": "足部畸形", "lang": "CN" } ], [ { "name": "Glabellar frown li...

[ "Toxin" ]

Pending

1,142,467,200,000

[ [ { "name": "Benign Essential Blepharospasm", "lang": "EN" }, { "name": "良性基础型眼睑痉挛", "lang": "CN" } ], [ { "name": "Foot Deformities", "lang": "EN" }, { "name": "足部畸形", "lang": "CN" } ], [ { "name": "Glabellar frown li...

[ "South Korea", "Russia", "Taiwan Province" ]

[ { "name": "伊匹木单抗", "lang": "CN" }, { "name": "Ipilimumab", "lang": "EN" }, { "name": "イピリムマブ（遺伝子組換え）", "lang": "JP" } ]

[ { "name": "Anti CTLA-4 monoclonal antibody", "lang": "EN" }, { "name": "Anti-CTLA-4 Mab", "lang": "EN" }, { "name": "Ipilimumab (Genetical Recombination)", "lang": "EN" }, { "name": "伊匹单抗", "lang": "CN" }, { "name": "依匹木单抗", "lang": "CN" }, { "name": "...

[ [ { "name": "Cytotoxic T-Lymphocyte-Associated Antigen 4", "lang": "EN" }, { "name": "细胞毒性T淋巴细胞相关抗原4", "lang": "CN" } ] ]

[ [ { "name": "Microsatellite instability-high Rectal Cancer", "lang": "EN" }, { "name": "MSI-H 直肠癌", "lang": "CN" } ], [ { "name": "PD-L1 positive Non-Small Cell Lung Cancer", "lang": "EN" }, { "name": "PD-L1阳性非小细胞肺癌", "lang": "CN" }...

[ "Monoclonal antibody" ]

Discontinued

1,301,011,200,000

[ [ { "name": "Melanoma", "lang": "EN" }, { "name": "黑色素瘤", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Japan", "Australia", "Iceland", "South Korea", "Liechtenstein", "Norway" ]

[ { "name": "Sulopenem etzadroxil/Probenecid", "lang": "EN" } ]

[ { "name": "Oral sulopenem", "lang": "EN" }, { "name": "Sulopenem etzadroxil", "lang": "EN" }, { "name": "Sulopenem etzadroxil (USAN)", "lang": "EN" } ]

[ [ { "name": "solute carrier family 22 member 6", "lang": "EN" } ], [ { "name": "Bacterial penicillin-binding protein", "lang": "EN" }, { "name": "细菌青霉素结合蛋白家族", "lang": "CN" } ] ]

[ [ { "name": "Urinary Tract Infections", "lang": "EN" }, { "name": "泌尿道感染", "lang": "CN" } ], [ { "name": "Bacterial Infections", "lang": "EN" }, { "name": "细菌感染", "lang": "CN" } ], [ { "name": "Community Acquired Pneum...

[ "Small molecule drug" ]

Phase 1 Clinical

1,729,814,400,000

[ [ { "name": "Urinary Tract Infections", "lang": "EN" }, { "name": "泌尿道感染", "lang": "CN" } ] ]

[ "United States" ]

[ { "name": "贝伐珠单抗生物类似药 (百奥泰生物)", "lang": "CN" }, { "name": "Bevacizumab biosimilar (Bio-Thera Solutions)", "lang": "EN" } ]

[ { "name": "BEVACIZUMAB-TNJN", "lang": "EN" }, { "name": "Bevacizumab Biosimilar (Bio-Thera Solutions, Ltd.)", "lang": "EN" }, { "name": "贝伐珠单抗生物类似药（百奥泰生物制药股份有限公司）", "lang": "CN" } ]

[ [ { "name": "Vascular endothelial growth factor A", "lang": "EN" }, { "name": "血管内皮生长因子A", "lang": "CN" } ] ]

[ [ { "name": "Advanced Renal Cell Carcinoma", "lang": "EN" }, { "name": "晚期肾细胞癌", "lang": "CN" } ], [ { "name": "EGFR positive Non-squamous non-small cell lung cancer", "lang": "EN" }, { "name": "EGFR阳性非鳞状非小细胞肺癌", "lang": "CN" } ],...

[ "Biosimilar", "Monoclonal antibody" ]

Approved

1,637,107,200,000

[ [ { "name": "Metastatic Colorectal Carcinoma", "lang": "EN" }, { "name": "转移性结直肠癌", "lang": "CN" } ], [ { "name": "Non-Small Cell Lung Cancer", "lang": "EN" }, { "name": "非小细胞肺癌", "lang": "CN" } ] ]

[ "United States", "China", "European Union", "Brazil", "Iceland", "Liechtenstein", "Norway" ]

[ { "name": "利美索龙", "lang": "CN" }, { "name": "Rimexolone", "lang": "EN" } ]

[ { "name": "Rimexel", "lang": "EN" }, { "name": "Rimexolon", "lang": "EN" }, { "name": "Rimexolone (USP/INN)", "lang": "EN" }, { "name": "Trimexolone", "lang": "EN" }, { "name": "Vexolon", "lang": "EN" } ]

[ [ { "name": "Glucocorticoid receptor", "lang": "EN" }, { "name": "糖皮质激素受体", "lang": "CN" } ] ]

[ [ { "name": "Uveitis", "lang": "EN" }, { "name": "葡萄膜炎", "lang": "CN" } ], [ { "name": "Dry Eye Syndromes", "lang": "EN" }, { "name": "干眼综合征", "lang": "CN" } ], [ { "name": "Post procedural inflammation", "lang":...

[ "Small molecule drug" ]

Withdrawn

788,745,600,000

[ [ { "name": "Post procedural inflammation", "lang": "EN" }, { "name": "术后炎症", "lang": "CN" } ], [ { "name": "Uveitis, Anterior", "lang": "EN" }, { "name": "前葡萄膜炎", "lang": "CN" } ] ]

[ "Germany" ]

[ { "name": "缬沙坦/苯磺酸氨氯地平/匹伐他汀钙水合物", "lang": "CN" }, { "name": "Valsartan/Amlodipine Besylate/Pitavastatin Calcium Hydrate", "lang": "EN" } ]

null

[ [ { "name": "HMG-CoA reductase", "lang": "EN" }, { "name": "羟甲基戊二酰辅酶A合酶", "lang": "CN" } ], [ { "name": "Angiotensin II Receptor Type 1", "lang": "EN" }, { "name": "血管紧张素II-1型受体", "lang": "CN" } ], [ { "name": "Voltage...

[ [ { "name": "Essential Hypertension", "lang": "EN" }, { "name": "原发性高血压", "lang": "CN" } ], [ { "name": "Primary hypercholesterolemia", "lang": "EN" }, { "name": "原发性高胆固醇血症", "lang": "CN" } ] ]

[ "Small molecule drug" ]

Approved

1,758,672,000,000

[ [ { "name": "Essential Hypertension", "lang": "EN" }, { "name": "原发性高血压", "lang": "CN" } ], [ { "name": "Primary hypercholesterolemia", "lang": "EN" }, { "name": "原发性高胆固醇血症", "lang": "CN" } ] ]

[ "South Korea" ]