drug_name listlengths 1 3 | alias listlengths 1 56 ⌀ | target listlengths 1 17 | disease listlengths 1 620 | drug_type listlengths 1 3 | global_highest_dev_status stringclasses 16
values | first_approved_date int64 -872,726,400,000 1,777B | first_approved_indication listlengths 1 21 | approval_country listlengths 1 37 |
|---|---|---|---|---|---|---|---|---|
[
{
"name": "磷酸索立德吉",
"lang": "CN"
},
{
"name": "Sonidegib Phosphate",
"lang": "EN"
}
] | [
{
"name": "Erismodegib",
"lang": "EN"
},
{
"name": "Erismodegib-phosphate",
"lang": "EN"
},
{
"name": "Sonidegib phosphate (USAN)",
"lang": "EN"
},
{
"name": "Sonidegib-phosphate",
"lang": "EN"
},
{
"name": "sonidegib",
"lang": "EN"
},
{
"name": "sonid... | [
[
{
"name": "Smoothened receptor",
"lang": "EN"
},
{
"name": "SMO受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Metastatic basal cell carcinoma",
"lang": "EN"
},
{
"name": "转移性基底细胞癌",
"lang": "CN"
}
],
[
{
"name": "Basal Cell Carcinoma",
"lang": "EN"
},
{
"name": "基底细胞癌",
"lang": "CN"
}
],
[
{
"name": "childhood CNS... | [
"Small molecule drug"
] | Discontinued | 1,437,696,000,000 | [
[
{
"name": "Basal Cell Carcinoma",
"lang": "EN"
},
{
"name": "基底细胞癌",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Canada",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "氨丁三醇奥扎格雷",
"lang": "CN"
},
{
"name": "Ozagrel Trometamol",
"lang": "EN"
}
] | [
{
"name": "Ozagrel Trometamol Concentrated Solution",
"lang": "EN"
},
{
"name": "奥扎格雷氨丁三醇",
"lang": "CN"
}
] | [
[
{
"name": "Thromboxane A2 synthase",
"lang": "EN"
},
{
"name": "血栓素A2合成酶",
"lang": "CN"
}
]
] | [
[
{
"name": "Platelet Aggregation, Spontaneous",
"lang": "EN"
},
{
"name": "自发性血小板聚集",
"lang": "CN"
}
],
[
{
"name": "Vasospasm",
"lang": "EN"
},
{
"name": "血管痉挛",
"lang": "CN"
}
],
[
{
"name": "Thrombosis",
"lan... | [
"Small molecule drug"
] | Pending | 1,628,726,400,000 | [
[
{
"name": "Platelet Aggregation, Spontaneous",
"lang": "EN"
},
{
"name": "自发性血小板聚集",
"lang": "CN"
}
],
[
{
"name": "Vasospasm",
"lang": "EN"
},
{
"name": "血管痉挛",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "乌司奴单抗生物类似药 (Accord BioPharma)",
"lang": "CN"
},
{
"name": "Ustekinumab biosimilar (Accord BioPharma)",
"lang": "EN"
}
] | [
{
"name": "Ustekinumab Biosimilar (Dong-A ST)",
"lang": "EN"
},
{
"name": "乌司奴单抗生物类似药（Dong-A ST）",
"lang": "CN"
}
] | [
[
{
"name": "Interleukin-12 subunit beta",
"lang": "EN"
},
{
"name": "白细胞介素-12β亚基",
"lang": "CN"
}
]
] | [
[
{
"name": "Ulcerative colitis, active moderate",
"lang": "EN"
},
{
"name": "活动性中度溃疡性结肠炎",
"lang": "CN"
}
],
[
{
"name": "Ulcerative colitis, active severe",
"lang": "EN"
},
{
"name": "活动性重度溃疡性结肠炎",
"lang": "CN"
}
],
[
{
... | [
"Biosimilar",
"Monoclonal antibody"
] | Approved | 1,733,961,600,000 | [
[
{
"name": "Arthritis, Psoriatic",
"lang": "EN"
},
{
"name": "银屑病关节炎",
"lang": "CN"
}
],
[
{
"name": "Crohn's disease, active moderate",
"lang": "EN"
},
{
"name": "活动性中度克罗恩病",
"lang": "CN"
}
],
[
{
"name": "Crohn's di... | [
"United States",
"European Union",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "恩沃利单抗",
"lang": "CN"
},
{
"name": "Envafolimab",
"lang": "EN"
}
] | [
{
"name": "重组人源化PDL1单域抗体Fc融合蛋白（康宁杰瑞）",
"lang": "CN"
}
] | [
[
{
"name": "Programmed death-ligand 1",
"lang": "EN"
},
{
"name": "程序性死亡配体1",
"lang": "CN"
}
]
] | [
[
{
"name": "Colorectal Cancer",
"lang": "EN"
},
{
"name": "结直肠癌",
"lang": "CN"
}
],
[
{
"name": "Microsatellite Instability-high Solid Tumors",
"lang": "EN"
},
{
"name": "MSI-H 实体瘤",
"lang": "CN"
}
],
[
{
"name": "Bil... | [
"Nanobody",
"Antibody fusion proteins"
] | Phase 2 Clinical | 1,637,712,000,000 | [
[
{
"name": "Colorectal Cancer",
"lang": "EN"
},
{
"name": "结直肠癌",
"lang": "CN"
}
],
[
{
"name": "Microsatellite Instability-high Solid Tumors",
"lang": "EN"
},
{
"name": "MSI-H 实体瘤",
"lang": "CN"
}
]
] | [
"China",
"Macao"
] |
[
{
"name": "帕利哌酮",
"lang": "CN"
},
{
"name": "Paliperidone",
"lang": "EN"
},
{
"name": "パリペリドン",
"lang": "JP"
}
] | [
{
"name": "9-hydroxyrisperidone",
"lang": "EN"
},
{
"name": "Paliperidone (JAN/USP/INN)",
"lang": "EN"
},
{
"name": "Paliperidone ER",
"lang": "EN"
},
{
"name": "帕利哌酮-PaliFlex",
"lang": "CN"
}
] | [
[
{
"name": "Serotonin 2a (5-HT2a) receptor",
"lang": "EN"
},
{
"name": "5-羟色胺2A受体",
"lang": "CN"
}
],
[
{
"name": "Dopamine D2 receptor",
"lang": "EN"
},
{
"name": "多巴胺D2受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Schizoaffective disorder",
"lang": "EN"
},
{
"name": "分裂情感性障碍",
"lang": "CN"
}
],
[
{
"name": "Schizophrenia",
"lang": "EN"
},
{
"name": "精神分裂症",
"lang": "CN"
}
],
[
{
"name": "Acute schizophrenia",
... | [
"Small molecule drug"
] | Pending | 1,166,486,400,000 | [
[
{
"name": "Schizophrenia",
"lang": "EN"
},
{
"name": "精神分裂症",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Japan",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "人胰岛素生物类似药（宜昌东阳光）",
"lang": "CN"
},
{
"name": "Recombinant human insulin (YiChang HEC ChangJiang Pharma)",
"lang": "EN"
}
] | [
{
"name": "重组人胰岛素生物类似药（宜昌东阳光）",
"lang": "CN"
}
] | [
[
{
"name": "Insulin receptor",
"lang": "EN"
},
{
"name": "胰岛素受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Diabetes Mellitus",
"lang": "EN"
},
{
"name": "糖尿病",
"lang": "CN"
}
]
] | [
"Biosimilar",
"Peptide Hormone"
] | Approved | 1,591,056,000,000 | [
[
{
"name": "Diabetes Mellitus",
"lang": "EN"
},
{
"name": "糖尿病",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "盐酸奥扎莫德",
"lang": "CN"
},
{
"name": "Ozanimod Hydrochloride",
"lang": "EN"
}
] | [
{
"name": "Ozanimod",
"lang": "EN"
},
{
"name": "Ozanimod hydrochloride (USAN)",
"lang": "EN"
},
{
"name": "Ozanimod-HCl",
"lang": "EN"
},
{
"name": "Ozanimod-hydrochloride",
"lang": "EN"
},
{
"name": "盐酸奥扎尼莫德",
"lang": "CN"
}
] | [
[
{
"name": "Sphingosine 1-phosphate receptor Edg-1",
"lang": "EN"
},
{
"name": "鞘氨醇-1-磷酸受体-Edg-1",
"lang": "CN"
}
],
[
{
"name": "Sphingosine 1-phosphate receptor Edg-8",
"lang": "EN"
},
{
"name": "鞘氨醇-1-磷酸受体-Edg-8",
"lang": "CN"
}... | [
[
{
"name": "Colitis, Ulcerative",
"lang": "EN"
},
{
"name": "溃疡性结肠炎",
"lang": "CN"
}
],
[
{
"name": "Multiple sclerosis relapse",
"lang": "EN"
},
{
"name": "复发性多发性硬化",
"lang": "CN"
}
],
[
{
"name": "Multiple Sclerosis... | [
"Small molecule drug"
] | Discontinued | 1,585,094,400,000 | [
[
{
"name": "Multiple Sclerosis",
"lang": "EN"
},
{
"name": "多发性硬化症",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "盐酸左旋体米那普仑",
"lang": "CN"
},
{
"name": "Levomilnacipran Hydrochloride",
"lang": "EN"
}
] | [
{
"name": "(1S,2R)-milnacipran",
"lang": "EN"
},
{
"name": "1S, 2R-milnacipran",
"lang": "EN"
},
{
"name": "LEVOMILNACIPRAN",
"lang": "EN"
},
{
"name": "Levomilnacipran ER",
"lang": "EN"
},
{
"name": "Levomilnacipran SR",
"lang": "EN"
},
{
"name": "Lev... | [
[
{
"name": "Norepinephrine transporter",
"lang": "EN"
},
{
"name": "去甲肾上腺素转运蛋白",
"lang": "CN"
}
],
[
{
"name": "Serotonin transporter",
"lang": "EN"
},
{
"name": "5-羟色胺转运体",
"lang": "CN"
}
]
] | [
[
{
"name": "Depressive Disorder, Major",
"lang": "EN"
},
{
"name": "重度抑郁症",
"lang": "CN"
}
],
[
{
"name": "Depressive Disorder",
"lang": "EN"
},
{
"name": "抑郁症",
"lang": "CN"
}
],
[
{
"name": "Acute Ischemic Stroke",
... | [
"Small molecule drug"
] | IND Approval | 1,374,710,400,000 | [
[
{
"name": "Depressive Disorder, Major",
"lang": "EN"
},
{
"name": "重度抑郁症",
"lang": "CN"
}
]
] | [
"United States"
] |
[
{
"name": "罗米司韦单抗",
"lang": "CN"
},
{
"name": "Romlusevimab",
"lang": "EN"
}
] | null | [
[
{
"name": "SARS-CoV-2 S protein",
"lang": "EN"
},
{
"name": "新冠病毒刺突蛋白",
"lang": "CN"
}
]
] | [
[
{
"name": "COVID-19",
"lang": "EN"
},
{
"name": "新型冠状病毒感染",
"lang": "CN"
}
]
] | [
"Monoclonal antibody"
] | Approved | 1,638,921,600,000 | [
[
{
"name": "COVID-19",
"lang": "EN"
},
{
"name": "新型冠状病毒感染",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "苯妥英钠",
"lang": "CN"
},
{
"name": "Phenytoin sodium",
"lang": "EN"
}
] | [
{
"name": "Phenytoin sodium (USP)",
"lang": "EN"
},
{
"name": "Phenytoin sodium for injection (JP17)",
"lang": "EN"
}
] | [
[
{
"name": "Sodium voltage-gated channel alpha subunits",
"lang": "EN"
},
{
"name": "电压门控钠通道α亚基家族",
"lang": "CN"
}
]
] | [
[
{
"name": "Seizures",
"lang": "EN"
},
{
"name": "癫痫发作",
"lang": "CN"
}
],
[
{
"name": "Status Epilepticus",
"lang": "EN"
},
{
"name": "癫痫持续状态",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Withdrawn | -436,665,600,000 | [
[
{
"name": "Seizures",
"lang": "EN"
},
{
"name": "癫痫发作",
"lang": "CN"
}
],
[
{
"name": "Status Epilepticus",
"lang": "EN"
},
{
"name": "癫痫持续状态",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "乌司奴单抗",
"lang": "CN"
},
{
"name": "Ustekinumab",
"lang": "EN"
},
{
"name": "ウステキヌマブ（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "Anti-interleukin-12 p40 monoclonal antibody",
"lang": "EN"
},
{
"name": "Stellara",
"lang": "EN"
},
{
"name": "Sterrara",
"lang": "EN"
},
{
"name": "Suterara",
"lang": "EN"
},
{
"name": "UST",
"lang": "EN"
},
{
"name": "Ustekinumab (Genetica... | [
[
{
"name": "Interleukin-12 subunit beta",
"lang": "EN"
},
{
"name": "白细胞介素-12β亚基",
"lang": "CN"
}
]
] | [
[
{
"name": "Colitis, Ulcerative",
"lang": "EN"
},
{
"name": "溃疡性结肠炎",
"lang": "CN"
}
],
[
{
"name": "Crohn Disease",
"lang": "EN"
},
{
"name": "克罗恩病",
"lang": "CN"
}
],
[
{
"name": "Arthritis, Psoriatic",
"lang"... | [
"Monoclonal antibody"
] | Pending | 1,232,064,000,000 | [
[
{
"name": "Arthritis, Psoriatic",
"lang": "EN"
},
{
"name": "银屑病关节炎",
"lang": "CN"
}
],
[
{
"name": "Crohn's disease, active moderate",
"lang": "EN"
},
{
"name": "活动性中度克罗恩病",
"lang": "CN"
}
],
[
{
"name": "Crohn's di... | [
"United States",
"China",
"European Union",
"Japan",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "mRNA-1083",
"lang": "EN"
}
] | [
{
"name": "Influenza and COVID-19 Vaccine(Moderna)",
"lang": "EN"
},
{
"name": "mRNA encoding haemagglutinin of B/Victoria lineage, haemagglutinin of influenza A/H1N1, haemagglutinin of influenza A/H3N2, SARS-CoV-2 spike protein NTD-RBD subdomains",
"lang": "EN"
}
] | [
[
{
"name": "Influenza virus hemagglutinin glycoproteins",
"lang": "EN"
},
{
"name": "血凝素",
"lang": "CN"
}
],
[
{
"name": "SARS-CoV-2 S protein",
"lang": "EN"
},
{
"name": "新冠病毒刺突蛋白",
"lang": "CN"
}
]
] | [
[
{
"name": "COVID-19",
"lang": "EN"
},
{
"name": "新型冠状病毒感染",
"lang": "CN"
}
],
[
{
"name": "Influenza, Human",
"lang": "EN"
},
{
"name": "流感病毒感染",
"lang": "CN"
}
]
] | [
"Prophylactic vaccine",
"mRNA vaccine"
] | Approved | 1,776,729,600,000 | [
[
{
"name": "COVID-19",
"lang": "EN"
},
{
"name": "新型冠状病毒感染",
"lang": "CN"
}
],
[
{
"name": "Influenza, Human",
"lang": "EN"
},
{
"name": "流感病毒感染",
"lang": "CN"
}
]
] | [
"European Union",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "泽贝妥单抗",
"lang": "CN"
},
{
"name": "Zuberitamab",
"lang": "EN"
}
] | [
{
"name": "Zebituzumab",
"lang": "EN"
},
{
"name": "Zuberitamab",
"lang": "EN"
},
{
"name": "重组人-鼠嵌合抗CD20单克隆抗体 (海正药业)",
"lang": "CN"
}
] | [
[
{
"name": "B-lymphocyte antigen CD20",
"lang": "EN"
},
{
"name": "B淋巴细胞抗原CD20",
"lang": "CN"
}
]
] | [
[
{
"name": "CD20 positive Diffuse Large B-Cell Lymphoma",
"lang": "EN"
},
{
"name": "CD20阳性弥漫性大B细胞淋巴瘤",
"lang": "CN"
}
],
[
{
"name": "Idiopathic Membranous Glomerulonephritis",
"lang": "EN"
},
{
"name": "特发性膜性肾病",
"lang": "CN"
}
... | [
"Monoclonal antibody"
] | Phase 2 Clinical | 1,683,849,600,000 | [
[
{
"name": "CD20 positive Diffuse Large B-Cell Lymphoma",
"lang": "EN"
},
{
"name": "CD20阳性弥漫性大B细胞淋巴瘤",
"lang": "CN"
}
]
] | [
"China",
"Macao"
] |
[
{
"name": "盐酸麻黄碱/对乙酰氨基酚/咖啡因",
"lang": "CN"
},
{
"name": "Ephedrine Hydrochloride/Acetaminophen/Caffeine",
"lang": "EN"
}
] | null | [
[
{
"name": "Adenosine A2a receptor",
"lang": "EN"
},
{
"name": "腺苷A2a受体",
"lang": "CN"
}
],
[
{
"name": "Adenosine A1 receptor",
"lang": "EN"
},
{
"name": "腺苷A1受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Common Cold",
"lang": "EN"
},
{
"name": "普通感冒",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Approved | 1,633,046,400,000 | [
[
{
"name": "Common Cold",
"lang": "EN"
},
{
"name": "普通感冒",
"lang": "CN"
}
]
] | [
"South Korea"
] |
[
{
"name": "莫匹罗星钙二水合物",
"lang": "CN"
},
{
"name": "Mupirocin Calcium",
"lang": "EN"
},
{
"name": "ムピロシンカルシウム水和物",
"lang": "JP"
}
] | [
{
"name": "MUP",
"lang": "EN"
},
{
"name": "Mupirocin Calcium Hydrate",
"lang": "EN"
},
{
"name": "Mupirocin calcium (USP)",
"lang": "EN"
},
{
"name": "Mupirocin calcium dihydrate",
"lang": "EN"
},
{
"name": "Mupirocin calcium hydrate (JP17)",
"lang": "EN"
}... | [
[
{
"name": "Isoleucyl-tRNA synthetase",
"lang": "EN"
},
{
"name": "异亮氨酰-tRNA合成酶",
"lang": "CN"
}
]
] | [
[
{
"name": "MRSA - Methicillin resistant Staphylococcus aureus infection",
"lang": "EN"
},
{
"name": "耐甲氧西林金黄色葡萄球菌感染",
"lang": "CN"
}
],
[
{
"name": "Staphylococcal Infections",
"lang": "EN"
},
{
"name": "葡萄球菌感染",
"lang": "CN"
}
... | [
"Small molecule drug"
] | Withdrawn | 682,128,000,000 | [
[
{
"name": "Staphylococcal Infections",
"lang": "EN"
},
{
"name": "葡萄球菌感染",
"lang": "CN"
}
]
] | [
"Japan",
"Australia"
] |
[
{
"name": "羟乙磺酸达尔西利",
"lang": "CN"
},
{
"name": "Dalpiciclib Isethionate",
"lang": "EN"
}
] | [
{
"name": "Dalpiciclib",
"lang": "EN"
},
{
"name": "达尔西利",
"lang": "CN"
}
] | [
[
{
"name": "Cyclin-dependent kinase 4",
"lang": "EN"
},
{
"name": "细胞周期蛋白依赖性激酶4",
"lang": "CN"
}
],
[
{
"name": "Cyclin-dependent kinase 6",
"lang": "EN"
},
{
"name": "细胞周期蛋白依赖性激酶6",
"lang": "CN"
}
]
] | [
[
{
"name": "Hormone receptor positive HER2 negative breast cancer",
"lang": "EN"
},
{
"name": "HR阳性/HER2阴性乳腺癌",
"lang": "CN"
}
],
[
{
"name": "HER2-negative breast cancer",
"lang": "EN"
},
{
"name": "HER2 阴性乳腺癌",
"lang": "CN"
}
]... | [
"Small molecule drug"
] | Phase 2 Clinical | 1,640,908,800,000 | [
[
{
"name": "Hormone receptor positive HER2 negative breast cancer",
"lang": "EN"
},
{
"name": "HR阳性/HER2阴性乳腺癌",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "培妥罗凝血素α",
"lang": "CN"
},
{
"name": "Turoctocog alfa pegol",
"lang": "EN"
},
{
"name": "ツロクトコグ アルファ ペゴル（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "Antihemophilic factor (recombinant), glycopegylated-exei",
"lang": "EN"
},
{
"name": "ESPEROCT",
"lang": "EN"
},
{
"name": "Long acting recombinant factor VIII",
"lang": "EN"
},
{
"name": "N8-GP RFVIII",
"lang": "EN"
},
{
"name": "N8-GP-RFVIII",
"la... | [
[
{
"name": "Coagulation factor X",
"lang": "EN"
},
{
"name": "凝血因子X",
"lang": "CN"
}
]
] | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
],
[
{
"name": "Hemorrhage",
"lang": "EN"
},
{
"name": "出血",
"lang": "CN"
}
]
] | [
"Recombinant coagulation factor"
] | Pending | 1,521,763,200,000 | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "Olipudase alfa",
"lang": "EN"
},
{
"name": "オリプダーゼ アルファ（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "OLIPUDASE ALFA-RPCP",
"lang": "EN"
},
{
"name": "Olipudase Alfa (Genetical Recombination)",
"lang": "EN"
},
{
"name": "Olipudase alfa (INN)",
"lang": "EN"
},
{
"name": "Olipudase alfa (genetical recombination) (JAN)",
"lang": "EN"
},
{
"name": "Recombin... | [
[
{
"name": "sphingomyelin phosphodiesterase 1",
"lang": "EN"
}
]
] | [
[
{
"name": "Acid sphingomyelinase deficiency",
"lang": "EN"
},
{
"name": "酸性鞘磷脂酶缺乏症",
"lang": "CN"
}
],
[
{
"name": "Niemann-Pick Disease, Type A",
"lang": "EN"
},
{
"name": "A型尼曼匹克病",
"lang": "CN"
}
]
] | [
"Enzyme"
] | Approved | 1,648,425,600,000 | [
[
{
"name": "Acid sphingomyelinase deficiency",
"lang": "EN"
},
{
"name": "酸性鞘磷脂酶缺乏症",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "丙戊酸钠",
"lang": "CN"
},
{
"name": "Sodium Valproate",
"lang": "EN"
},
{
"name": "バルプロ酸ナトリウム",
"lang": "JP"
}
] | [
{
"name": "SV",
"lang": "EN"
},
{
"name": "VPA-Na",
"lang": "EN"
},
{
"name": "Valproate Sodium",
"lang": "EN"
}
] | [
[
{
"name": "Histone deacetylase",
"lang": "EN"
},
{
"name": "组蛋白去乙酰化酶家族",
"lang": "CN"
}
]
] | [
[
{
"name": "Nervous System Diseases",
"lang": "EN"
},
{
"name": "神经系统疾病",
"lang": "CN"
}
],
[
{
"name": "Bipolar Disorder",
"lang": "EN"
},
{
"name": "躁郁症",
"lang": "CN"
}
],
[
{
"name": "Migraine Disorders",
"l... | [
"Small molecule drug"
] | Preclinical | 138,585,600,000 | [
[
{
"name": "Epilepsy",
"lang": "EN"
},
{
"name": "癫痫",
"lang": "CN"
}
]
] | [
"China",
"Japan"
] |
[
{
"name": "左旋氨氯地平/替米沙坦",
"lang": "CN"
},
{
"name": "Levamlodipine/Telmisartan",
"lang": "EN"
}
] | [
{
"name": "S-amlodipine/telmisartan",
"lang": "EN"
},
{
"name": "Telminuvo Tab",
"lang": "EN"
},
{
"name": "Telmisartan/S-amlodipine",
"lang": "EN"
},
{
"name": "Telmunivo",
"lang": "EN"
},
{
"name": "苯磺酸左旋氨氯地平二水合物/替米沙坦",
"lang": "CN"
}
] | [
[
{
"name": "Angiotensin II Receptor Type 1",
"lang": "EN"
},
{
"name": "血管紧张素II-1型受体",
"lang": "CN"
}
],
[
{
"name": "Voltage-gated L-type calcium channel",
"lang": "EN"
},
{
"name": "L-型电压门控性钙通道家族",
"lang": "CN"
}
]
] | [
[
{
"name": "Hypertension",
"lang": "EN"
},
{
"name": "高血压",
"lang": "CN"
}
],
[
{
"name": "Essential Hypertension",
"lang": "EN"
},
{
"name": "原发性高血压",
"lang": "CN"
}
],
[
{
"name": "Dyslipidemias",
"lang": "EN"... | [
"Small molecule drug"
] | Pending | 1,359,590,400,000 | [
[
{
"name": "Hypertension",
"lang": "EN"
},
{
"name": "高血压",
"lang": "CN"
}
]
] | [
"South Korea"
] |
[
{
"name": "泽美洛韦/玛佐瑞韦单抗",
"lang": "CN"
},
{
"name": "Zamerovimab/Mazorelvimab",
"lang": "EN"
}
] | [
{
"name": "Mazorelvimab/Zamerovimab",
"lang": "EN"
},
{
"name": "重组抗狂犬病毒人源化单克隆抗体(深圳龙瑞药业有限公司)",
"lang": "CN"
}
] | [
[
{
"name": "RABV-G",
"lang": "EN"
},
{
"name": "狂犬病毒G蛋白",
"lang": "CN"
}
]
] | [
[
{
"name": "Rabies",
"lang": "EN"
},
{
"name": "狂犬病",
"lang": "CN"
}
],
[
{
"name": "Communicable Diseases, Imported",
"lang": "EN"
},
{
"name": "输入性传染病",
"lang": "CN"
}
],
[
{
"name": "Zoonoses",
"lang": "EN"
... | [
"Monoclonal antibody"
] | Approved | 1,717,459,200,000 | [
[
{
"name": "Rabies",
"lang": "EN"
},
{
"name": "狂犬病",
"lang": "CN"
}
]
] | [
"China",
"Macao"
] |
[
{
"name": "环硅酸锆钠",
"lang": "CN"
},
{
"name": "Sodium Zirconium Cyclosilicate",
"lang": "EN"
},
{
"name": "ジルコニウムシクロケイ酸ナトリウム水和物",
"lang": "JP"
}
] | [
{
"name": "Sodium Zirconium Cyclosilicate Hydrate",
"lang": "EN"
},
{
"name": "Sodium Zirconium Cyclosilicate Powder",
"lang": "EN"
},
{
"name": "Sodium zirconium cyclosilicate (USAN)",
"lang": "EN"
},
{
"name": "Sodium zirconium cyclosilicate hydrate (JAN)",
"lang": "EN"... | [
[
{
"name": "Potassium",
"lang": "EN"
},
{
"name": "钾",
"lang": "CN"
}
]
] | [
[
{
"name": "Hyperkalemia",
"lang": "EN"
},
{
"name": "高钾血症",
"lang": "CN"
}
],
[
{
"name": "Heart Failure",
"lang": "EN"
},
{
"name": "心脏衰竭",
"lang": "CN"
}
],
[
{
"name": "Arrhythmias, Cardiac",
"lang": "EN"
... | [
"Small molecule drug"
] | Discontinued | 1,521,676,800,000 | [
[
{
"name": "Hyperkalemia",
"lang": "EN"
},
{
"name": "高钾血症",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway",
"Russia"
] |
[
{
"name": "Efanesoctocog alfa",
"lang": "EN"
},
{
"name": "エフアネソクトコグ アルファ（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "Factor VIII recombinant",
"lang": "EN"
},
{
"name": "Recombinant factor VIII(Amunix, Inc.)",
"lang": "EN"
},
{
"name": "XTENylated Factor VIII",
"lang": "EN"
},
{
"name": "antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl",
"lang": "EN"
},
... | [
[
{
"name": "Coagulation factor X",
"lang": "EN"
},
{
"name": "凝血因子X",
"lang": "CN"
}
]
] | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
],
[
{
"name": "Hemorrhage",
"lang": "EN"
},
{
"name": "出血",
"lang": "CN"
}
],
[
{
"name": "Von Willebrand Disease, Type 2",
"lang": "E... | [
"Fc fusion protein",
"Recombinant coagulation factor",
"XTEN fusion protein"
] | Phase 3 Clinical | 1,677,024,000,000 | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Japan",
"United Kingdom",
"Canada",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "阿达木单抗生物类似药 (辉瑞制药)",
"lang": "CN"
},
{
"name": "Adalimumab-AFZB",
"lang": "EN"
}
] | [
{
"name": "Adalimumab biosimilar (Pfizer)",
"lang": "EN"
},
{
"name": "Adalimumab-afzb",
"lang": "EN"
}
] | [
[
{
"name": "Tumor necrosis factor α",
"lang": "EN"
},
{
"name": "肿瘤坏死因子α",
"lang": "CN"
}
]
] | [
[
{
"name": "Polyarticular Juvenile Idiopathic Arthritis",
"lang": "EN"
},
{
"name": "多关节型幼年特发性关节炎",
"lang": "CN"
}
],
[
{
"name": "Axial Spondyloarthritis",
"lang": "EN"
},
{
"name": "中轴性脊柱关节炎",
"lang": "CN"
}
],
[
{
... | [
"Biosimilar",
"Monoclonal antibody"
] | Approved | 1,573,776,000,000 | [
[
{
"name": "Ankylosing Spondylitis",
"lang": "EN"
},
{
"name": "强直性脊柱炎",
"lang": "CN"
}
],
[
{
"name": "Arthritis, Psoriatic",
"lang": "EN"
},
{
"name": "银屑病关节炎",
"lang": "CN"
}
],
[
{
"name": "Colitis, Ulcerative",
... | [
"United States",
"European Union",
"Canada",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "阿托伐他汀钙",
"lang": "CN"
},
{
"name": "Atorvastatin Calcium",
"lang": "EN"
},
{
"name": "アトルバスタチンカルシウム水和物",
"lang": "JP"
}
] | [
{
"name": "Atorvastatin Calcium Hydrate",
"lang": "EN"
},
{
"name": "Atorvastatin calcium (USP)",
"lang": "EN"
},
{
"name": "Atorvastatin calcium hydrate (JP17)",
"lang": "EN"
},
{
"name": "Atorvastatin calcium trihydrate",
"lang": "EN"
},
{
"name": "Atorvastation... | [
[
{
"name": "HMG-CoA reductase",
"lang": "EN"
},
{
"name": "羟甲基戊二酰辅酶A合酶",
"lang": "CN"
}
]
] | [
[
{
"name": "Heart Failure",
"lang": "EN"
},
{
"name": "心脏衰竭",
"lang": "CN"
}
],
[
{
"name": "Angina Pectoris",
"lang": "EN"
},
{
"name": "心绞痛",
"lang": "CN"
}
],
[
{
"name": "Myocardial Infarction",
"lang": "EN"... | [
"Small molecule drug"
] | Pending | 850,780,800,000 | [
[
{
"name": "Homozygous familial hypercholesterolemia",
"lang": "EN"
},
{
"name": "纯合子家族性高胆固醇血症",
"lang": "CN"
}
],
[
{
"name": "Hyperlipidemia Type IIa",
"lang": "EN"
},
{
"name": "II a型高脂蛋白血症",
"lang": "CN"
}
],
[
{
... | [
"United States",
"China",
"Japan",
"Australia"
] |
[
{
"name": "盐酸二甲双胍/盐酸西格列汀",
"lang": "CN"
},
{
"name": "Metformin Hydrochloride/Sitagliptin Hydrochloride",
"lang": "EN"
}
] | null | [
[
{
"name": "Dipeptidyl peptidase IV",
"lang": "EN"
},
{
"name": "二肽基肽酶IV",
"lang": "CN"
}
],
[
{
"name": "Protein kinase AMP-activated non-catalytic subunit beta 1",
"lang": "EN"
},
{
"name": "腺苷酸活化蛋白激酶亚基β1",
"lang": "CN"
}
]
] | [
[
{
"name": "Diabetes Mellitus, Type 2",
"lang": "EN"
},
{
"name": "2型糖尿病",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Approved | 1,644,969,600,000 | [
[
{
"name": "Diabetes Mellitus, Type 2",
"lang": "EN"
},
{
"name": "2型糖尿病",
"lang": "CN"
}
]
] | [
"European Union",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "盐酸氯普鲁卡因",
"lang": "CN"
},
{
"name": "Chloroprocaine Hydrochloride",
"lang": "EN"
}
] | [
{
"name": "2-chloroprocaine",
"lang": "EN"
},
{
"name": "4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester",
"lang": "EN"
},
{
"name": "Ampres",
"lang": "EN"
},
{
"name": "Chloroprocain",
"lang": "EN"
},
{
"name": "Chloroprocaine",
"lang": "EN"
},
{... | [
[
{
"name": "Sodium channels",
"lang": "EN"
},
{
"name": "钠通道",
"lang": "CN"
}
]
] | [
[
{
"name": "Anesthesia",
"lang": "EN"
},
{
"name": "麻醉",
"lang": "CN"
}
],
[
{
"name": "Neurolytic Block",
"lang": "EN"
},
{
"name": "神经阻滞",
"lang": "CN"
}
],
[
{
"name": "Tissue infiltration",
"lang": "EN"
... | [
"Small molecule drug"
] | Pending | -467,424,000,000 | [
[
{
"name": "Anesthesia",
"lang": "EN"
},
{
"name": "麻醉",
"lang": "CN"
}
],
[
{
"name": "Neurolytic Block",
"lang": "EN"
},
{
"name": "神经阻滞",
"lang": "CN"
}
],
[
{
"name": "Tissue infiltration",
"lang": "EN"
... | [
"United States",
"China",
"Canada",
"Austria",
"Belgium",
"Germany",
"Spain",
"France",
"Ireland",
"Italy",
"Poland"
] |
[
{
"name": "硫酸索西美雷塞",
"lang": "CN"
},
{
"name": "Sosimerasib",
"lang": "EN"
}
] | [
{
"name": "硫酸索美来昔",
"lang": "CN"
}
] | [
[
{
"name": "GTPase KRas G12C",
"lang": "EN"
},
{
"name": "KRAS G12C突变",
"lang": "CN"
}
]
] | [
[
{
"name": "KRAS G12C mutant Non-small Cell Lung Cancer",
"lang": "EN"
},
{
"name": "KRAS G12C突变非小细胞肺癌",
"lang": "CN"
}
],
[
{
"name": "KRAS G12C mutation Solid Tumors",
"lang": "EN"
},
{
"name": "KRAS G12C突变的实体瘤",
"lang": "CN"
}
... | [
"Small molecule drug"
] | Phase 1 Clinical | 1,771,977,600,000 | [
[
{
"name": "KRAS G12C mutant Non-small Cell Lung Cancer",
"lang": "EN"
},
{
"name": "KRAS G12C突变非小细胞肺癌",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "塞利尼索",
"lang": "CN"
},
{
"name": "Selinexor",
"lang": "EN"
}
] | [
{
"name": "CRM1-nuclear-export-inhibitor",
"lang": "EN"
},
{
"name": "NEXPOVIO",
"lang": "EN"
},
{
"name": "Selinexor",
"lang": "EN"
},
{
"name": "Selinexor (USAN/INN)",
"lang": "EN"
}
] | [
[
{
"name": "Exportin-1 protein",
"lang": "EN"
},
{
"name": "输出蛋白1",
"lang": "CN"
}
],
[
{
"name": "acyl-CoA dehydrogenase short chain",
"lang": "EN"
}
]
] | [
[
{
"name": "Follicular Lymphoma",
"lang": "EN"
},
{
"name": "滤泡性淋巴瘤",
"lang": "CN"
}
],
[
{
"name": "Refractory Multiple Myeloma",
"lang": "EN"
},
{
"name": "难治性多发性骨髓瘤",
"lang": "CN"
}
],
[
{
"name": "Relapse multiple... | [
"Small molecule drug"
] | Discontinued | 1,562,112,000,000 | [
[
{
"name": "Multiple Myeloma",
"lang": "EN"
},
{
"name": "多发性骨髓瘤",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"United Kingdom",
"Canada",
"Australia",
"Hong Kong",
"Indonesia",
"Israel",
"Iceland",
"South Korea",
"Liechtenstein",
"Macao",
"Malaysia",
"Norway",
"Singapore",
"Thailand",
"Taiwan Province"
] |
[
{
"name": "重组人生长激素(Novo Nordisk A/S)",
"lang": "CN"
},
{
"name": "Somatropin(Novo Nordisk A/S)",
"lang": "EN"
},
{
"name": "ソマトロピン（遺伝子組換え）(Novo Nordisk A/S)",
"lang": "JP"
}
] | [
{
"name": "Norditropin NordiFlex",
"lang": "EN"
},
{
"name": "Norditropin NordiLet",
"lang": "EN"
},
{
"name": "Norditropin NordiPen",
"lang": "EN"
},
{
"name": "Norditropin S",
"lang": "EN"
},
{
"name": "Norditropin SimpleXx",
"lang": "EN"
},
{
"name"... | [
[
{
"name": "Growth hormone receptor",
"lang": "EN"
},
{
"name": "生长激素受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Growth Disorders",
"lang": "EN"
},
{
"name": "生长障碍",
"lang": "CN"
}
],
[
{
"name": "Growth hormone deficiency",
"lang": "EN"
},
{
"name": "生长激素缺乏症",
"lang": "CN"
}
],
[
{
"name": "Dwarfism",
"lang": ... | [
"Peptide Hormone"
] | Pending | 596,851,200,000 | [
[
{
"name": "Dwarfism, Pituitary",
"lang": "EN"
},
{
"name": "垂体性侏儒症",
"lang": "CN"
}
]
] | [
"United States",
"China",
"Japan"
] |
[
{
"name": "环磷酰胺",
"lang": "CN"
},
{
"name": "Cyclophosphamide",
"lang": "EN"
},
{
"name": "シクロホスファミド水和物",
"lang": "JP"
}
] | [
{
"name": "(+-)-Cyclophosphamide",
"lang": "EN"
},
{
"name": "(RS)-Cyclophosphamide",
"lang": "EN"
},
{
"name": "2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide",
"lang": "EN"
},
{
"name": "Anhydrous cyclophosphamide",
"lang": "EN"
},
{
"n... | [
[
{
"name": "DNA",
"lang": "EN"
},
{
"name": "DNA",
"lang": "CN"
}
]
] | [
[
{
"name": "Graft vs Host Disease",
"lang": "EN"
},
{
"name": "移植物抗宿主病",
"lang": "CN"
}
],
[
{
"name": "Amyloidosis",
"lang": "EN"
},
{
"name": "淀粉样变性",
"lang": "CN"
}
],
[
{
"name": "Pheochromocytoma",
"lang": ... | [
"Small molecule drug"
] | Pending | -319,593,600,000 | [
[
{
"name": "Acute Lymphoblastic Leukemia",
"lang": "EN"
},
{
"name": "急性淋巴细胞白血病",
"lang": "CN"
}
],
[
{
"name": "Acute Monocytic Leukemia",
"lang": "EN"
},
{
"name": "急性单核细胞白血病",
"lang": "CN"
}
],
[
{
"name": "Acute M... | [
"United States",
"China",
"Japan",
"Australia"
] |
[
{
"name": "组氨酸铜",
"lang": "CN"
},
{
"name": "Copper Histidine",
"lang": "EN"
}
] | [
{
"name": "Copper histidinate",
"lang": "EN"
}
] | [
[
{
"name": "ATPase copper transporting alpha",
"lang": "EN"
}
]
] | [
[
{
"name": "Menkes Kinky Hair Syndrome",
"lang": "EN"
},
{
"name": "Menkes综合征",
"lang": "CN"
}
],
[
{
"name": "Occipital Horn Syndrome",
"lang": "EN"
},
{
"name": "枕角综合征",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Approved | 1,768,176,000,000 | [
[
{
"name": "Menkes Kinky Hair Syndrome",
"lang": "EN"
},
{
"name": "Menkes综合征",
"lang": "CN"
}
]
] | [
"United States"
] |
[
{
"name": "盐酸伐昔洛韦",
"lang": "CN"
},
{
"name": "Valacyclovir Hydrochloride",
"lang": "EN"
},
{
"name": "バラシクロビル塩酸塩",
"lang": "JP"
}
] | [
{
"name": "L-Valine ester with 9-((2-hydroxyethoxy)methyl)guanine",
"lang": "EN"
},
{
"name": "L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl ester",
"lang": "EN"
},
{
"name": "Talavir",
"lang": "EN"
},
{
"name": "Va1acic1ovir Hydroch1oride",
"lang": ... | [
[
{
"name": "DNA polymerase",
"lang": "EN"
},
{
"name": "DNA聚合酶",
"lang": "CN"
}
],
[
{
"name": "Viral enzyme",
"lang": "EN"
},
{
"name": "病毒酶",
"lang": "CN"
}
]
] | [
[
{
"name": "Cytomegalovirus Infections",
"lang": "EN"
},
{
"name": "巨细胞病毒感染",
"lang": "CN"
}
],
[
{
"name": "Herpes Zoster Ophthalmicus",
"lang": "EN"
},
{
"name": "眼带状疱疹",
"lang": "CN"
}
],
[
{
"name": "Herpes Simple... | [
"Small molecule drug"
] | Pending | 803,865,600,000 | [
[
{
"name": "Chickenpox",
"lang": "EN"
},
{
"name": "水痘",
"lang": "CN"
}
],
[
{
"name": "Herpes Genitalis",
"lang": "EN"
},
{
"name": "生殖器疱疹",
"lang": "CN"
}
],
[
{
"name": "Herpes Labialis",
"lang": "EN"
},
... | [
"United States",
"China",
"Japan",
"Australia"
] |
[
{
"name": "人凝血酶原复合物 (兰州兰生血液制品)",
"lang": "CN"
},
{
"name": "Human Prothrombin Complex (Lanzhou Lansheng Blood Products)",
"lang": "EN"
}
] | null | [
[
{
"name": "Coagulation factor X",
"lang": "EN"
},
{
"name": "凝血因子X",
"lang": "CN"
}
],
[
{
"name": "Coagulation factor IX",
"lang": "EN"
},
{
"name": "凝血因子IX",
"lang": "CN"
}
],
[
{
"name": "Coagulation factor VII",
... | [
[
{
"name": "Hemophilia B",
"lang": "EN"
},
{
"name": "血友病B",
"lang": "CN"
}
]
] | [
"Non-recombinant coagulation factor"
] | Approved | 1,727,308,800,000 | [
[
{
"name": "Hemophilia B",
"lang": "EN"
},
{
"name": "血友病B",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "右泛醇",
"lang": "CN"
},
{
"name": "Dexpanthenol",
"lang": "EN"
},
{
"name": "パンテノール",
"lang": "JP"
}
] | [
{
"name": "(+)-Panthenol",
"lang": "EN"
},
{
"name": "(2R)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide",
"lang": "EN"
},
{
"name": "Bepanthene",
"lang": "EN"
},
{
"name": "Bepantol",
"lang": "EN"
},
{
"name": "D(+)-Panthenol",
"lang": "EN"
},
... | [
[
{
"name": "Muscarinic acetylcholine receptor",
"lang": "EN"
},
{
"name": "毒蕈碱型乙酰胆碱受体家族",
"lang": "CN"
}
]
] | [
[
{
"name": "Pantothenic acid deficiency",
"lang": "EN"
},
{
"name": "泛酸缺乏症",
"lang": "CN"
}
],
[
{
"name": "Vitamin B Deficiency",
"lang": "EN"
},
{
"name": "维生素B缺乏症",
"lang": "CN"
}
],
[
{
"name": "Burns",
"lan... | [
"Small molecule drug"
] | Discontinued | -340,416,000,000 | [
[
{
"name": "Pantothenic acid deficiency",
"lang": "EN"
},
{
"name": "泛酸缺乏症",
"lang": "CN"
}
]
] | [
"China",
"Japan"
] |
[
{
"name": "阿达木单抗生物类似药 (苏州信达生物)",
"lang": "CN"
},
{
"name": "Adalimumab biosimilar(Innovent Biologics (Suzhou) Co. Ltd.)",
"lang": "EN"
}
] | [
{
"name": "Adalimumab biosimilar",
"lang": "EN"
},
{
"name": "SULINNO",
"lang": "EN"
}
] | [
[
{
"name": "Tumor necrosis factor α",
"lang": "EN"
},
{
"name": "肿瘤坏死因子α",
"lang": "CN"
}
]
] | [
[
{
"name": "Crohn Disease",
"lang": "EN"
},
{
"name": "克罗恩病",
"lang": "CN"
}
],
[
{
"name": "Pediatric Crohn's Disease",
"lang": "EN"
},
{
"name": "小儿克罗恩病",
"lang": "CN"
}
],
[
{
"name": "Ankylosing Spondylitis",
... | [
"Biosimilar",
"Monoclonal antibody"
] | Approved | 1,599,004,800,000 | [
[
{
"name": "Ankylosing Spondylitis",
"lang": "EN"
},
{
"name": "强直性脊柱炎",
"lang": "CN"
}
],
[
{
"name": "Polyarticular Juvenile Idiopathic Arthritis",
"lang": "EN"
},
{
"name": "多关节型幼年特发性关节炎",
"lang": "CN"
}
],
[
{
"na... | [
"China",
"Macao"
] |
[
{
"name": "克拉夫定",
"lang": "CN"
},
{
"name": "Clevudine",
"lang": "EN"
}
] | [
{
"name": "2'-Fluoro-5-methyl-beta-L-arabinofuranosyluracil",
"lang": "EN"
},
{
"name": "Clevudine (USAN)",
"lang": "EN"
},
{
"name": "L-FMAU",
"lang": "EN"
},
{
"name": "Levovir",
"lang": "EN"
},
{
"name": "Revovir",
"lang": "EN"
},
{
"name": "克来夫定",
... | [
[
{
"name": "HBV DNA Polymerase",
"lang": "EN"
},
{
"name": "乙型肝炎病毒DNA聚合酶",
"lang": "CN"
}
]
] | [
[
{
"name": "Hepatitis B",
"lang": "EN"
},
{
"name": "乙型肝炎",
"lang": "CN"
}
],
[
{
"name": "Hepatitis B, Chronic",
"lang": "EN"
},
{
"name": "慢性乙型肝炎",
"lang": "CN"
}
],
[
{
"name": "Complete atrioventricular block",
... | [
"Small molecule drug"
] | Pending | 992,390,400,000 | [
[
{
"name": "Hepatitis B",
"lang": "EN"
},
{
"name": "乙型肝炎",
"lang": "CN"
}
]
] | [
"Philippines"
] |
[
{
"name": "门冬酰胺酶",
"lang": "CN"
},
{
"name": "Asparaginase (Erwinia)",
"lang": "EN"
}
] | [
{
"name": "Asparaginase (Erwinia)",
"lang": "EN"
},
{
"name": "Asparaginase Erwinia Chrysanthemi (Recombinant)",
"lang": "EN"
},
{
"name": "Asparaginase Erwinia Chrysanthemi(Jazz Pharmaceuticals)",
"lang": "EN"
},
{
"name": "Asparaginase Erwinia chrysanthemi",
"lang": "EN... | [
[
{
"name": "Asparagine",
"lang": "EN"
},
{
"name": "天冬酰胺",
"lang": "CN"
}
]
] | [
[
{
"name": "Precursor B-Cell Lymphoblastic Leukemia-Lymphoma",
"lang": "EN"
},
{
"name": "前体B细胞成淋巴细胞白血病淋巴瘤",
"lang": "CN"
}
],
[
{
"name": "Adult Lymphoblastic Lymphoma",
"lang": "EN"
},
{
"name": "淋巴母细胞淋巴瘤",
"lang": "CN"
}
],
... | [
"Enzyme"
] | Discontinued | 1,172,534,400,000 | [
[
{
"name": "Acute Lymphoblastic Leukemia",
"lang": "EN"
},
{
"name": "急性淋巴细胞白血病",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "培重组人凝血因子Ⅷ",
"lang": "CN"
},
{
"name": "Rurioctocog alfa pegol",
"lang": "EN"
},
{
"name": "ルリオクトコグ アルファ ペゴル（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "Adynovi",
"lang": "EN"
},
{
"name": "Antihemophilic Factor (Recombinant), PEGylated",
"lang": "EN"
},
{
"name": "EHL rFVIII PEG",
"lang": "EN"
},
{
"name": "Extended half-life recombinant FVIII",
"lang": "EN"
},
{
"name": "Full-length longer-acting rFVI... | [
[
{
"name": "Coagulation factor X",
"lang": "EN"
},
{
"name": "凝血因子X",
"lang": "CN"
}
]
] | [
[
{
"name": "Coagulation Protein Disorders",
"lang": "EN"
},
{
"name": "凝血因子缺乏症",
"lang": "CN"
}
],
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
],
[
{
"name": "Hemorrhage",
"lang"... | [
"Recombinant coagulation factor"
] | Phase 3 Clinical | 1,447,372,800,000 | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Japan",
"Canada",
"Australia",
"Switzerland",
"Colombia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "替莫瑞林",
"lang": "CN"
},
{
"name": "Tesamorelin Acetate",
"lang": "EN"
}
] | [
{
"name": "EGRIFTA",
"lang": "EN"
},
{
"name": "EGRIFTA SV",
"lang": "EN"
},
{
"name": "GHRH(1-44)",
"lang": "EN"
},
{
"name": "N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet)",
"lang": "EN"
},
{
"name": "Tesamorelin",
"lang": "EN"
},
{
... | [
[
{
"name": "Growth hormone releasing factor",
"lang": "EN"
},
{
"name": "生长激素释放因子",
"lang": "CN"
}
]
] | [
[
{
"name": "HIV Infections",
"lang": "EN"
},
{
"name": "HIV感染",
"lang": "CN"
}
],
[
{
"name": "Lipodystrophy",
"lang": "EN"
},
{
"name": "脂肪营养不良",
"lang": "CN"
}
],
[
{
"name": "Fibrosis, Liver",
"lang": "EN"
... | [
"Synthetic peptide"
] | Phase 2 Clinical | 1,289,347,200,000 | [
[
{
"name": "HIV Infections",
"lang": "EN"
},
{
"name": "HIV感染",
"lang": "CN"
}
],
[
{
"name": "Lipodystrophy",
"lang": "EN"
},
{
"name": "脂肪营养不良",
"lang": "CN"
}
]
] | [
"United States"
] |
[
{
"name": "英夫利西单抗生物类似药 (上海百迈博)",
"lang": "CN"
},
{
"name": "Infliximab biosimilar(Shanghai Biomabs Pharmaceuticals Co., Ltd.)",
"lang": "EN"
}
] | [
{
"name": "Infliximab Biosimilar (Shanghai Biomabs Pharmaceuticals Co., Ltd.)",
"lang": "EN"
},
{
"name": "英夫利西单抗生物类似药（Shanghai Biomabs Pharmaceuticals Co., Ltd.）",
"lang": "CN"
}
] | [
[
{
"name": "Tumor necrosis factor α",
"lang": "EN"
},
{
"name": "肿瘤坏死因子α",
"lang": "CN"
}
]
] | [
[
{
"name": "Ankylosing Spondylitis",
"lang": "EN"
},
{
"name": "强直性脊柱炎",
"lang": "CN"
}
],
[
{
"name": "Colitis, Ulcerative",
"lang": "EN"
},
{
"name": "溃疡性结肠炎",
"lang": "CN"
}
],
[
{
"name": "Crohn Disease",
"l... | [
"Biosimilar",
"Monoclonal antibody"
] | Approved | 1,626,220,800,000 | [
[
{
"name": "Ankylosing Spondylitis",
"lang": "EN"
},
{
"name": "强直性脊柱炎",
"lang": "CN"
}
],
[
{
"name": "Colitis, Ulcerative",
"lang": "EN"
},
{
"name": "溃疡性结肠炎",
"lang": "CN"
}
],
[
{
"name": "Crohn Disease",
"l... | [
"China",
"Peru"
] |
[
{
"name": "奥莱扎森",
"lang": "CN"
},
{
"name": "Olezarsen Sodium",
"lang": "EN"
}
] | [
{
"name": "AKCEA-APOCIII-LRx",
"lang": "EN"
},
{
"name": "APOC-III-L-Rx",
"lang": "EN"
},
{
"name": "IONIS-APOCIII-LRx",
"lang": "EN"
},
{
"name": "ISIS-APOCIII-LRx",
"lang": "EN"
},
{
"name": "Olezarsen",
"lang": "EN"
},
{
"name": "奥乐扎森",
"lang": ... | [
[
{
"name": "Apolipoprotein C-III",
"lang": "EN"
},
{
"name": "载脂蛋白C-Ⅲ",
"lang": "CN"
}
]
] | [
[
{
"name": "Hypertriglyceridemia",
"lang": "EN"
},
{
"name": "高甘油三酯血症",
"lang": "CN"
}
],
[
{
"name": "Familial chylomicronaemia syndrome",
"lang": "EN"
},
{
"name": "家族性乳糜微粒血症综合征",
"lang": "CN"
}
]
] | [
"ASO"
] | Approved | 1,734,566,400,000 | [
[
{
"name": "Familial chylomicronaemia syndrome",
"lang": "EN"
},
{
"name": "家族性乳糜微粒血症综合征",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"United Kingdom",
"Canada",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "雷扎芬净",
"lang": "CN"
},
{
"name": "Rezafungin acetate",
"lang": "EN"
}
] | [
{
"name": "Biafungin",
"lang": "EN"
},
{
"name": "Rezafungin",
"lang": "EN"
},
{
"name": "Rezafungin acetate (USAN)",
"lang": "EN"
},
{
"name": "Rezafungin cation",
"lang": "EN"
},
{
"name": "Rezafungin ion",
"lang": "EN"
},
{
"name": "盐酸瑞扎佛辛",
"la... | [
[
{
"name": "1,3-beta-glucan synthase",
"lang": "EN"
},
{
"name": "1,3-β-葡聚糖合酶",
"lang": "CN"
}
]
] | [
[
{
"name": "Candidemia",
"lang": "EN"
},
{
"name": "念珠菌血症",
"lang": "CN"
}
],
[
{
"name": "Candidiasis, Invasive",
"lang": "EN"
},
{
"name": "侵袭性念珠菌病",
"lang": "CN"
}
],
[
{
"name": "Invasive Fungal Infections",
... | [
"Synthetic peptide",
"Cyclic Peptide"
] | Pending | 1,679,443,200,000 | [
[
{
"name": "Candidemia",
"lang": "EN"
},
{
"name": "念珠菌血症",
"lang": "CN"
}
],
[
{
"name": "Candidiasis, Invasive",
"lang": "EN"
},
{
"name": "侵袭性念珠菌病",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"United Kingdom",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "人凝血酶原复合物 (同路生物)",
"lang": "CN"
},
{
"name": "Human prothrombin complex (Tonrol)",
"lang": "EN"
}
] | null | [
[
{
"name": "Coagulation factor X",
"lang": "EN"
},
{
"name": "凝血因子X",
"lang": "CN"
}
],
[
{
"name": "Coagulation factor IX",
"lang": "EN"
},
{
"name": "凝血因子IX",
"lang": "CN"
}
],
[
{
"name": "Coagulation factor VII",
... | [
[
{
"name": "Hemorrhage",
"lang": "EN"
},
{
"name": "出血",
"lang": "CN"
}
],
[
{
"name": "Hemophilia B",
"lang": "EN"
},
{
"name": "血友病B",
"lang": "CN"
}
]
] | [
"Non-recombinant coagulation factor"
] | Approved | 1,625,529,600,000 | [
[
{
"name": "Hemorrhage",
"lang": "EN"
},
{
"name": "出血",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "芦康沙妥珠单抗",
"lang": "CN"
},
{
"name": "Sacituzumab tirumotecan",
"lang": "EN"
}
] | [
{
"name": "Sac-TMT",
"lang": "EN"
},
{
"name": "TROP-2-targeted antibody-drug conjugate",
"lang": "EN"
}
] | [
[
{
"name": "DNA topoisomerase I",
"lang": "EN"
},
{
"name": "DNA拓扑异构酶I",
"lang": "CN"
}
],
[
{
"name": "Tumor-associated calcium signal transducer 2",
"lang": "EN"
},
{
"name": "肿瘤相关钙信号传感器2",
"lang": "CN"
}
]
] | [
[
{
"name": "Hormone receptor positive HER2 negative breast cancer",
"lang": "EN"
},
{
"name": "HR阳性/HER2阴性乳腺癌",
"lang": "CN"
}
],
[
{
"name": "EGFR-mutated non-small Cell Lung Cancer",
"lang": "EN"
},
{
"name": "EGFR突变的非小细胞肺癌",
"lang":... | [
"Antibody drug conjugate (ADC)"
] | Phase 3 Clinical | 1,732,233,600,000 | [
[
{
"name": "Triple Negative Breast Cancer",
"lang": "EN"
},
{
"name": "三阴性乳腺癌",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "米库氯铵",
"lang": "CN"
},
{
"name": "Mivacurium Chloride",
"lang": "EN"
}
] | [
{
"name": "Mivacurium chloride (USAN/INN)",
"lang": "EN"
}
] | [
[
{
"name": "Nicotinic receptors",
"lang": "EN"
},
{
"name": "烟碱受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Anesthesia",
"lang": "EN"
},
{
"name": "麻醉",
"lang": "CN"
}
],
[
{
"name": "Hyperemesis Gravidarum",
"lang": "EN"
},
{
"name": "妊娠剧吐",
"lang": "CN"
}
]
] | [
"Chemical drugs"
] | Withdrawn | 696,038,400,000 | [
[
{
"name": "Anesthesia",
"lang": "EN"
},
{
"name": "麻醉",
"lang": "CN"
}
]
] | [
"United States"
] |
[
{
"name": "重组人凝血因子Ⅷ(正大天晴)",
"lang": "CN"
},
{
"name": "Recombinant coagulation factor VIII(Chia Tai-Tianqing)",
"lang": "EN"
}
] | null | [
[
{
"name": "Coagulation factor X",
"lang": "EN"
},
{
"name": "凝血因子X",
"lang": "CN"
}
]
] | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
]
] | [
"Recombinant coagulation factor"
] | Approved | 1,693,267,200,000 | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "缬苯那嗪",
"lang": "CN"
},
{
"name": "Valbenazine Tosylate",
"lang": "EN"
},
{
"name": "バルベナジントシル酸塩",
"lang": "JP"
}
] | [
{
"name": "INGREZZA",
"lang": "EN"
},
{
"name": "VMAT2-inhibtor-Neurocrine-Biosciences",
"lang": "EN"
},
{
"name": "Valbenazine",
"lang": "EN"
},
{
"name": "Valbenazine Tosilate",
"lang": "EN"
},
{
"name": "Valbenazine-tosylate",
"lang": "EN"
}
] | [
[
{
"name": "Synaptic vesicular amine transporter",
"lang": "EN"
},
{
"name": "突触囊泡单胺转运体",
"lang": "CN"
}
]
] | [
[
{
"name": "Huntington Disease",
"lang": "EN"
},
{
"name": "亨廷顿舞蹈病",
"lang": "CN"
}
],
[
{
"name": "Tardive Dyskinesia",
"lang": "EN"
},
{
"name": "迟发性运动障碍",
"lang": "CN"
}
],
[
{
"name": "Chorea",
"lang": "EN"
... | [
"Small molecule drug"
] | Phase 2 Clinical | 1,491,868,800,000 | [
[
{
"name": "Tardive Dyskinesia",
"lang": "EN"
},
{
"name": "迟发性运动障碍",
"lang": "CN"
}
]
] | [
"United States",
"Japan",
"South Korea"
] |
[
{
"name": "Nystatin/Neomycin Sulphate/Polymyxin B Sulphate",
"lang": "EN"
}
] | [
{
"name": "nystatin/neomycin sulphate/polymyxin B sulphate",
"lang": "EN"
}
] | [
[
{
"name": "Ergosterol",
"lang": "EN"
},
{
"name": "麦角固醇",
"lang": "CN"
}
],
[
{
"name": "Bacterial penicillin-binding protein",
"lang": "EN"
},
{
"name": "细菌青霉素结合蛋白家族",
"lang": "CN"
}
]
] | [
[
{
"name": "Vaginitis",
"lang": "EN"
},
{
"name": "阴道炎",
"lang": "CN"
}
],
[
{
"name": "Bacterial Vaginosis",
"lang": "EN"
},
{
"name": "细菌性阴道炎",
"lang": "CN"
}
],
[
{
"name": "Infective vaginitis",
"lang": "EN"... | [
"Polypeptide antibiotic"
] | Pending | 855,619,200,000 | [
[
{
"name": "Vaginitis",
"lang": "EN"
},
{
"name": "阴道炎",
"lang": "CN"
}
]
] | [
"Rwanda"
] |
[
{
"name": "贝伐珠单抗生物类似药(上海生物制品研究所)",
"lang": "CN"
},
{
"name": "Bevacizumab biosimilar(Shanghai Institute of Biological Products)",
"lang": "EN"
}
] | [
{
"name": "Bevacizumab Biosimilar (Shanghai Institute of Biological Products Co., Ltd.)",
"lang": "EN"
},
{
"name": "贝伐珠单抗生物类似药（上海生物制品研究所有限责任公司）",
"lang": "CN"
}
] | [
[
{
"name": "Vascular endothelial growth factor A",
"lang": "EN"
},
{
"name": "血管内皮生长因子A",
"lang": "CN"
}
]
] | [
[
{
"name": "Fallopian Tube Carcinoma",
"lang": "EN"
},
{
"name": "输卵管癌",
"lang": "CN"
}
],
[
{
"name": "Hepatocellular Carcinoma",
"lang": "EN"
},
{
"name": "肝细胞癌",
"lang": "CN"
}
],
[
{
"name": "Metastatic Colorectal... | [
"Biosimilar",
"Monoclonal antibody"
] | Approved | 1,736,294,400,000 | [
[
{
"name": "Fallopian Tube Carcinoma",
"lang": "EN"
},
{
"name": "输卵管癌",
"lang": "CN"
}
],
[
{
"name": "Hepatocellular Carcinoma",
"lang": "EN"
},
{
"name": "肝细胞癌",
"lang": "CN"
}
],
[
{
"name": "Metastatic Colorectal... | [
"China"
] |
[
{
"name": "枸橼酸伊沙佐米",
"lang": "CN"
},
{
"name": "Ixazomib citrate",
"lang": "EN"
},
{
"name": "イキサゾミブクエン酸エステル",
"lang": "JP"
}
] | [
{
"name": "Ixazomib citrate (JAN/USAN)",
"lang": "EN"
},
{
"name": "ixazomib",
"lang": "EN"
},
{
"name": "伊沙佐米",
"lang": "CN"
}
] | [
[
{
"name": "Proteasome",
"lang": "EN"
},
{
"name": "蛋白酶体",
"lang": "CN"
}
]
] | [
[
{
"name": "Multiple Myeloma",
"lang": "EN"
},
{
"name": "多发性骨髓瘤",
"lang": "CN"
}
],
[
{
"name": "Plasmacytoma",
"lang": "EN"
},
{
"name": "浆细胞瘤",
"lang": "CN"
}
],
[
{
"name": "Recurrent Multiple Myeloma",
"lan... | [
"Small molecule drug"
] | Pending | 1,447,977,600,000 | [
[
{
"name": "Multiple Myeloma",
"lang": "EN"
},
{
"name": "多发性骨髓瘤",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "阿戈美拉汀",
"lang": "CN"
},
{
"name": "Agomelatine",
"lang": "EN"
}
] | [
{
"name": "Alodil",
"lang": "EN"
},
{
"name": "Melitor",
"lang": "EN"
},
{
"name": "Thymanax",
"lang": "EN"
},
{
"name": "Valdoxan",
"lang": "EN"
},
{
"name": "Vestin",
"lang": "EN"
}
] | [
[
{
"name": "Serotonin 2c (5-HT2c) receptor",
"lang": "EN"
},
{
"name": "5-羟色胺2C受体",
"lang": "CN"
}
],
[
{
"name": "Melatonin receptor 1A",
"lang": "EN"
},
{
"name": "褪黑激素受体1A",
"lang": "CN"
}
],
[
{
"name": "Melatonin... | [
[
{
"name": "Generalized anxiety disorder",
"lang": "EN"
},
{
"name": "广泛性焦虑障碍",
"lang": "CN"
}
],
[
{
"name": "Depressive Disorder, Major",
"lang": "EN"
},
{
"name": "重度抑郁症",
"lang": "CN"
}
],
[
{
"name": "Depressive ... | [
"Small molecule drug"
] | IND Approval | 1,235,001,600,000 | [
[
{
"name": "Depressive Disorder, Major",
"lang": "EN"
},
{
"name": "重度抑郁症",
"lang": "CN"
}
]
] | [
"China",
"European Union",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "雷珠单抗",
"lang": "CN"
},
{
"name": "Ranibizumab (Genentech)",
"lang": "EN"
},
{
"name": "ラニビズマブ（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "ACCENTRIX",
"lang": "EN"
},
{
"name": "AMD Fab",
"lang": "EN"
},
{
"name": "AMD-rhuFab-V2",
"lang": "EN"
},
{
"name": "Anti-VEGF fragment",
"lang": "EN"
},
{
"name": "Rabinismab",
"lang": "EN"
},
{
"name": "Ranibizumab (Genetical Recombinati... | [
[
{
"name": "Vascular endothelial growth factor A",
"lang": "EN"
},
{
"name": "血管内皮生长因子A",
"lang": "CN"
}
]
] | [
[
{
"name": "Myopic choroidal neovascularization",
"lang": "EN"
},
{
"name": "近视脉络膜新生血管",
"lang": "CN"
}
],
[
{
"name": "Diabetic Retinopathy",
"lang": "EN"
},
{
"name": "糖尿病性视网膜病变",
"lang": "CN"
}
],
[
{
"name": "Reti... | [
"Fab fragment"
] | Pending | 1,151,625,600,000 | [
[
{
"name": "Wet age-related macular degeneration",
"lang": "EN"
},
{
"name": "湿性年龄相关性黄斑变性",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "EuCorVac-19",
"lang": "EN"
}
] | [
{
"name": "COVID19 Vaccine (EuBiologics)",
"lang": "EN"
},
{
"name": "SARS-CoV-2 Spike Protein Vaccine(Recombinant) (EuBiologics)",
"lang": "EN"
}
] | [
[
{
"name": "SARS-CoV-2 S protein",
"lang": "EN"
},
{
"name": "新冠病毒刺突蛋白",
"lang": "CN"
}
]
] | [
[
{
"name": "COVID-19",
"lang": "EN"
},
{
"name": "新型冠状病毒感染",
"lang": "CN"
}
]
] | [
"Prophylactic vaccine"
] | Approved | 1,673,308,800,000 | [
[
{
"name": "COVID-19",
"lang": "EN"
},
{
"name": "新型冠状病毒感染",
"lang": "CN"
}
]
] | [
"Philippines"
] |
[
{
"name": "人纤维蛋白原(上海生物制品研究所)",
"lang": "CN"
},
{
"name": "Human fibrinogen(Shanghai Institute of Biological Products Co., Ltd.)",
"lang": "EN"
}
] | null | [
[
{
"name": "Fibrin",
"lang": "EN"
},
{
"name": "纤维蛋白",
"lang": "CN"
}
]
] | [
[
{
"name": "Afibrinogenemia",
"lang": "EN"
},
{
"name": "纤维蛋白原缺乏血症",
"lang": "CN"
}
],
[
{
"name": "Acquired fibrinogen deficiency",
"lang": "EN"
},
{
"name": "获得性纤维蛋白原缺乏",
"lang": "CN"
}
],
[
{
"name": "Congenital fi... | [
"Non-recombinant coagulation factor"
] | IND Approval | 852,076,800,000 | [
[
{
"name": "Afibrinogenemia",
"lang": "EN"
},
{
"name": "纤维蛋白原缺乏血症",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "妥拉美替尼",
"lang": "CN"
},
{
"name": "Tunlametinib",
"lang": "EN"
}
] | null | [
[
{
"name": "Dual specificity mitogen-activated protein kinase kinase 1",
"lang": "EN"
},
{
"name": "双特异性丝裂原活化蛋白激酶激酶1",
"lang": "CN"
}
],
[
{
"name": "Dual specificity mitogen-activated protein kinase kinase 2",
"lang": "EN"
},
{
"name": "双特异... | [
[
{
"name": "NRAS Mutant Melanoma",
"lang": "EN"
},
{
"name": "NRAS突变黑色素瘤",
"lang": "CN"
}
],
[
{
"name": "BRAF V600E mutant Colorectal Cancer",
"lang": "EN"
},
{
"name": "BRAF V600E突变结直肠癌",
"lang": "CN"
}
],
[
{
"name... | [
"Small molecule drug"
] | Approved | 1,710,201,600,000 | [
[
{
"name": "NRAS Mutant Melanoma",
"lang": "EN"
},
{
"name": "NRAS突变黑色素瘤",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "草酸艾司西酞普兰",
"lang": "CN"
},
{
"name": "Escitalopram Oxalate",
"lang": "EN"
},
{
"name": "エスシタロプラムシュウ酸塩",
"lang": "JP"
}
] | [
{
"name": "Cipralex",
"lang": "EN"
},
{
"name": "Entact",
"lang": "EN"
},
{
"name": "Escitalopram",
"lang": "EN"
},
{
"name": "Escitalopram oxalate (JAN/USP)",
"lang": "EN"
},
{
"name": "S-citalopram",
"lang": "EN"
},
{
"name": "Seroplex",
"lang": ... | [
[
{
"name": "Serotonin transporter",
"lang": "EN"
},
{
"name": "5-羟色胺转运体",
"lang": "CN"
}
]
] | [
[
{
"name": "Phobia, Social",
"lang": "EN"
},
{
"name": "社交恐怖症",
"lang": "CN"
}
],
[
{
"name": "Depressive Disorder",
"lang": "EN"
},
{
"name": "抑郁症",
"lang": "CN"
}
],
[
{
"name": "Panic Disorder",
"lang": "EN"
... | [
"Small molecule drug"
] | Pending | 1,020,729,600,000 | [
[
{
"name": "Anxiety Disorders",
"lang": "EN"
},
{
"name": "焦虑症",
"lang": "CN"
}
],
[
{
"name": "Depressive Disorder, Major",
"lang": "EN"
},
{
"name": "重度抑郁症",
"lang": "CN"
}
],
[
{
"name": "Obsessive-Compulsive Disor... | [
"United States",
"China",
"Japan",
"United Kingdom",
"Australia",
"Austria",
"Belgium",
"Brazil",
"Cyprus",
"Denmark",
"Spain",
"Finland",
"France",
"Greece",
"Ireland",
"Iceland",
"Italy",
"Luxembourg",
"Latvia",
"Malta",
"Norway",
"Portugal",
"Sweden"
] |
[
{
"name": "头孢他啶/他唑巴坦钠",
"lang": "CN"
},
{
"name": "Ceftazidime/Tazobactam Sodium",
"lang": "EN"
}
] | [
{
"name": "头孢他啶他唑巴坦钠",
"lang": "CN"
}
] | [
[
{
"name": "Bacterial penicillin-binding protein",
"lang": "EN"
},
{
"name": "细菌青霉素结合蛋白家族",
"lang": "CN"
}
],
[
{
"name": "Beta Lactamase",
"lang": "EN"
},
{
"name": "β-内酰胺酶",
"lang": "CN"
}
]
] | [
[
{
"name": "Infectious Diseases",
"lang": "EN"
},
{
"name": "感染",
"lang": "CN"
}
],
[
{
"name": "Genitourinary tract infection",
"lang": "EN"
},
{
"name": "泌尿系统感染",
"lang": "CN"
}
],
[
{
"name": "Respiratory Tract Inf... | [
"Small molecule drug"
] | Phase 2 Clinical | 1,268,611,200,000 | [
[
{
"name": "Infectious Diseases",
"lang": "EN"
},
{
"name": "感染",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "戊柔比星",
"lang": "CN"
},
{
"name": "Valrubicin",
"lang": "EN"
}
] | [
{
"name": "N-Trifluoroacetyladriamycin-14-valerate",
"lang": "EN"
},
{
"name": "Valrubicin (USP/INN)",
"lang": "EN"
},
{
"name": "Valtaxin",
"lang": "EN"
}
] | [
[
{
"name": "Topoisomerase II",
"lang": "EN"
},
{
"name": "拓扑异构酶II",
"lang": "CN"
}
]
] | [
[
{
"name": "Carcinoma in situ of bladder",
"lang": "EN"
},
{
"name": "膀胱原位癌",
"lang": "CN"
}
],
[
{
"name": "Carcinoma in Situ",
"lang": "EN"
},
{
"name": "原位癌",
"lang": "CN"
}
],
[
{
"name": "Non-Muscle Invasive Blad... | [
"Small molecule drug"
] | Pending | 906,681,600,000 | [
[
{
"name": "Carcinoma in situ of bladder",
"lang": "EN"
},
{
"name": "膀胱原位癌",
"lang": "CN"
}
]
] | [
"United States"
] |
[
{
"name": "替伊莫单抗",
"lang": "CN"
},
{
"name": "Ibritumomab Tiuxetan",
"lang": "EN"
},
{
"name": "イブリツモマブ チウキセタン（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "111In-ibritumomab tiuxetan",
"lang": "EN"
},
{
"name": "Ibritumomab",
"lang": "EN"
},
{
"name": "Ibritumomab tiuxetan (USAN/INN)",
"lang": "EN"
},
{
"name": "Ibritumomab tiuxetan (genetical recombination) (JAN)",
"lang": "EN"
},
{
"name": "Indium-111 Ib... | [
[
{
"name": "B-lymphocyte antigen CD20",
"lang": "EN"
},
{
"name": "B淋巴细胞抗原CD20",
"lang": "CN"
}
]
] | [
[
{
"name": "Mantle-Cell Lymphoma",
"lang": "EN"
},
{
"name": "套细胞淋巴瘤",
"lang": "CN"
}
],
[
{
"name": "B-Cell Lymphoma",
"lang": "EN"
},
{
"name": "B细胞淋巴瘤",
"lang": "CN"
}
],
[
{
"name": "Follicular Lymphoma",
"l... | [
"Radiolabeled antibody",
"Therapeutic radiopharmaceuticals"
] | Discontinued | 1,014,076,800,000 | [
[
{
"name": "Non-Hodgkin Lymphoma",
"lang": "EN"
},
{
"name": "非霍奇金淋巴瘤",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Japan",
"Hong Kong",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "人凝血酶原复合物（成都蓉生）",
"lang": "CN"
},
{
"name": "Human prothrombin complex (Chengdu Rongsheng)",
"lang": "EN"
}
] | null | [
[
{
"name": "Coagulation factor X",
"lang": "EN"
},
{
"name": "凝血因子X",
"lang": "CN"
}
],
[
{
"name": "Coagulation factor IX",
"lang": "EN"
},
{
"name": "凝血因子IX",
"lang": "CN"
}
],
[
{
"name": "Coagulation factor VII",
... | [
[
{
"name": "Hemorrhage",
"lang": "EN"
},
{
"name": "出血",
"lang": "CN"
}
],
[
{
"name": "Hemophilia B",
"lang": "EN"
},
{
"name": "血友病B",
"lang": "CN"
}
]
] | [
"Non-recombinant coagulation factor"
] | Approved | 1,607,990,400,000 | [
[
{
"name": "Hemorrhage",
"lang": "EN"
},
{
"name": "出血",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "溶组织梭菌胶原酶",
"lang": "CN"
},
{
"name": "Collagenase Clostridium histolyticum(Biospecifics Technologies Corp)",
"lang": "EN"
},
{
"name": "コラゲナーゼ（クロストリジウム ヒストリチクム）",
"lang": "JP"
}
] | [
{
"name": "CCH",
"lang": "EN"
},
{
"name": "Clostridial collagenase",
"lang": "EN"
},
{
"name": "Collagenase (Clostridium Histolyticum)",
"lang": "EN"
},
{
"name": "Collagenase Clostridium histolyticum (Endo/SOBI/Asahi Kasei)",
"lang": "EN"
},
{
"name": "Collagena... | [
[
{
"name": "Collagen",
"lang": "EN"
},
{
"name": "胶原蛋白",
"lang": "CN"
}
]
] | [
[
{
"name": "Cellulite",
"lang": "EN"
},
{
"name": "脂肪团",
"lang": "CN"
}
],
[
{
"name": "Penile Induration",
"lang": "EN"
},
{
"name": "阴茎硬结",
"lang": "CN"
}
],
[
{
"name": "Dupuytren Contracture",
"lang": "EN"
... | [
"Enzyme"
] | Phase 3 Clinical | 1,265,068,800,000 | [
[
{
"name": "Dupuytren Contracture",
"lang": "EN"
},
{
"name": "掌腱膜挛缩症",
"lang": "CN"
}
]
] | [
"United States",
"Japan"
] |
[
{
"name": "门冬胰岛素生物类似药 (通化东宝)",
"lang": "CN"
},
{
"name": "Insulin aspart biosimilar(Tonghua Dongbao Pharmaceutical Co., Ltd.)",
"lang": "EN"
}
] | [
{
"name": "EZ RAPID",
"lang": "EN"
},
{
"name": "Insulin Aspart 30",
"lang": "EN"
},
{
"name": "Insulin Aspart 50",
"lang": "EN"
}
] | [
[
{
"name": "Insulin receptor",
"lang": "EN"
},
{
"name": "胰岛素受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Diabetes Mellitus",
"lang": "EN"
},
{
"name": "糖尿病",
"lang": "CN"
}
],
[
{
"name": "Diabetes Mellitus, Type 2",
"lang": "EN"
},
{
"name": "2型糖尿病",
"lang": "CN"
}
],
[
{
"name": "Diabetes Mellitus, Type 1",... | [
"Biosimilar",
"Peptide Hormone"
] | Approved | 1,634,601,600,000 | [
[
{
"name": "Diabetes Mellitus, Type 1",
"lang": "EN"
},
{
"name": "1型糖尿病",
"lang": "CN"
}
]
] | [
"China",
"Dominican Republic",
"Indonesia"
] |
[
{
"name": "Conestat alfa",
"lang": "EN"
}
] | [
{
"name": "C1 Esterase Inhibitor (Recombinant)",
"lang": "EN"
},
{
"name": "C1 Inhibitor (Recombinant)",
"lang": "EN"
},
{
"name": "Complement C1 esterase inhibitor",
"lang": "EN"
},
{
"name": "Conestat alfa (INN)",
"lang": "EN"
},
{
"name": "Human C1-inhibitor (r... | [
[
{
"name": "Complement C1s",
"lang": "EN"
},
{
"name": "补体C1s",
"lang": "CN"
}
],
[
{
"name": "Kallikreins",
"lang": "EN"
},
{
"name": "激肽释放酶",
"lang": "CN"
}
],
[
{
"name": "Mannan-binding lectin serine proteases",
... | [
[
{
"name": "Hereditary Angioedema",
"lang": "EN"
},
{
"name": "遗传性血管性水肿",
"lang": "CN"
}
],
[
{
"name": "Acute Ischemic Stroke",
"lang": "EN"
},
{
"name": "急性缺血性卒中",
"lang": "CN"
}
],
[
{
"name": "Acute Kidney Injury"... | [
"Recombinant protein"
] | Discontinued | 1,288,224,000,000 | [
[
{
"name": "Hereditary Angioedema",
"lang": "EN"
},
{
"name": "遗传性血管性水肿",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "布尔韦肽",
"lang": "CN"
},
{
"name": "Bulevirtide Acetate",
"lang": "EN"
}
] | [
{
"name": "Bulevirtide",
"lang": "EN"
},
{
"name": "MyrB",
"lang": "EN"
},
{
"name": "Myrcludex-B",
"lang": "EN"
},
{
"name": "Myrcludex-B-MYR Pharma",
"lang": "EN"
}
] | [
[
{
"name": "Sodium/bile acid cotransporter",
"lang": "EN"
},
{
"name": "钠-胆汁酸转运蛋白",
"lang": "CN"
}
]
] | [
[
{
"name": "Virus Diseases",
"lang": "EN"
},
{
"name": "病毒感染",
"lang": "CN"
}
],
[
{
"name": "Hepatitis D, Chronic",
"lang": "EN"
},
{
"name": "慢性丁型肝炎",
"lang": "CN"
}
],
[
{
"name": "Hepatitis D",
"lang": "EN"
... | [
"Synthetic peptide"
] | Pending | 1,596,153,600,000 | [
[
{
"name": "Hepatitis D, Chronic",
"lang": "EN"
},
{
"name": "慢性丁型肝炎",
"lang": "CN"
}
]
] | [
"European Union",
"Canada",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "艾伐卡托",
"lang": "CN"
},
{
"name": "Ivacaftor",
"lang": "EN"
}
] | [
{
"name": "IVA",
"lang": "EN"
}
] | [
[
{
"name": "Cystic fibrosis transmembrane conductance regulator",
"lang": "EN"
},
{
"name": "囊性纤维化跨膜传导调节因子",
"lang": "CN"
}
]
] | [
[
{
"name": "Cystic Fibrosis",
"lang": "EN"
},
{
"name": "囊性纤维化",
"lang": "CN"
}
],
[
{
"name": "Bronchitis, Chronic",
"lang": "EN"
},
{
"name": "慢性支气管炎",
"lang": "CN"
}
],
[
{
"name": "Cough",
"lang": "EN"
}... | [
"Small molecule drug"
] | Pending | 1,327,968,000,000 | [
[
{
"name": "Cystic Fibrosis",
"lang": "EN"
},
{
"name": "囊性纤维化",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Canada",
"Australia",
"Switzerland",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "双氯芬酸钾",
"lang": "CN"
},
{
"name": "Diclofenac Potassium",
"lang": "EN"
}
] | [
{
"name": "Diclofenac potassium (USP)",
"lang": "EN"
}
] | [
[
{
"name": "Cyclooxygenases",
"lang": "EN"
},
{
"name": "环氧化酶",
"lang": "CN"
}
]
] | [
[
{
"name": "Migraine Disorders",
"lang": "EN"
},
{
"name": "偏头痛",
"lang": "CN"
}
],
[
{
"name": "Acute Pain",
"lang": "EN"
},
{
"name": "急性疼痛",
"lang": "CN"
}
],
[
{
"name": "Pain",
"lang": "EN"
},
{
... | [
"Small molecule drug"
] | Withdrawn | 754,099,200,000 | [
[
{
"name": "Osteoarthritis",
"lang": "EN"
},
{
"name": "骨关节炎",
"lang": "CN"
}
],
[
{
"name": "Pain",
"lang": "EN"
},
{
"name": "疼痛",
"lang": "CN"
}
],
[
{
"name": "Primary dysmenorrhea",
"lang": "EN"
},
... | [
"United States",
"China"
] |
[
{
"name": "拉多替尼二盐酸盐",
"lang": "CN"
},
{
"name": "Radotinib Dihydrochloride",
"lang": "EN"
}
] | [
{
"name": "Radotinib",
"lang": "EN"
},
{
"name": "Radotinib hydrochloride",
"lang": "EN"
},
{
"name": "Supect",
"lang": "EN"
},
{
"name": "盐酸拉多替尼",
"lang": "CN"
}
] | [
[
{
"name": "Bcr-Abl tyrosine kinase",
"lang": "EN"
},
{
"name": "bcr-abl酪氨酸激酶",
"lang": "CN"
}
],
[
{
"name": "Platelet-derived growth factor receptor",
"lang": "EN"
},
{
"name": "血小板衍生生长因子受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Philadelphia chromosome positive chronic myelogenous leukemia",
"lang": "EN"
},
{
"name": "费城染色体阳性慢性粒细胞白血病",
"lang": "CN"
}
],
[
{
"name": "refractory chronic myelocytic leukemia",
"lang": "EN"
},
{
"name": "难治性慢性粒细胞白血病",
"... | [
"Small molecule drug"
] | Phase 3 Clinical | 1,325,721,600,000 | [
[
{
"name": "Philadelphia chromosome positive chronic myelogenous leukemia",
"lang": "EN"
},
{
"name": "费城染色体阳性慢性粒细胞白血病",
"lang": "CN"
}
]
] | [
"South Korea"
] |
[
{
"name": "司来吉兰",
"lang": "CN"
},
{
"name": "Selegiline",
"lang": "EN"
}
] | [
{
"name": "Selegiline (USAN/INN)",
"lang": "EN"
}
] | [
[
{
"name": "Monoamine oxidase B",
"lang": "EN"
},
{
"name": "单胺氧化酶B",
"lang": "CN"
}
]
] | [
[
{
"name": "Depressive Disorder, Major",
"lang": "EN"
},
{
"name": "重度抑郁症",
"lang": "CN"
}
],
[
{
"name": "Cocaine-Related Disorders",
"lang": "EN"
},
{
"name": "可卡因相关疾病",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Pending | 1,140,998,400,000 | [
[
{
"name": "Depressive Disorder, Major",
"lang": "EN"
},
{
"name": "重度抑郁症",
"lang": "CN"
}
]
] | [
"United States"
] |
[
{
"name": "西洛他唑/瑞舒伐他汀钙",
"lang": "CN"
},
{
"name": "Cilostazol/Rosuvastatin Calcium",
"lang": "EN"
}
] | null | [
[
{
"name": "HMG-CoA reductase",
"lang": "EN"
},
{
"name": "羟甲基戊二酰辅酶A合酶",
"lang": "CN"
}
],
[
{
"name": "Phosphodiesterase 3",
"lang": "EN"
},
{
"name": "磷酸二酯酶3",
"lang": "CN"
}
]
] | [
[
{
"name": "Atherosclerosis",
"lang": "EN"
},
{
"name": "动脉粥样硬化",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Approved | 1,756,252,800,000 | [
[
{
"name": "Atherosclerosis",
"lang": "EN"
},
{
"name": "动脉粥样硬化",
"lang": "CN"
}
]
] | [
"South Korea"
] |
[
{
"name": "醋酸阿托西班",
"lang": "CN"
},
{
"name": "Atosiban acetate",
"lang": "EN"
}
] | [
{
"name": "Antocile",
"lang": "EN"
},
{
"name": "Antocin",
"lang": "EN"
},
{
"name": "Antocin II",
"lang": "EN"
},
{
"name": "atosiban",
"lang": "EN"
},
{
"name": "dTVT",
"lang": "EN"
},
{
"name": "deTVT",
"lang": "EN"
},
{
"name": "阿托西班",
... | [
[
{
"name": "Vasopressin receptor",
"lang": "EN"
},
{
"name": "血管加压素受体家族",
"lang": "CN"
}
],
[
{
"name": "Oxytocin receptor",
"lang": "EN"
},
{
"name": "催产素受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Obstetric Labor, Premature",
"lang": "EN"
},
{
"name": "早产",
"lang": "CN"
}
],
[
{
"name": "Ventricular Fibrillation, Paroxysmal Familial, 1",
"lang": "EN"
},
{
"name": "1型阵发性家族性心室颤动",
"lang": "CN"
}
]
] | [
"Synthetic peptide",
"Cyclic Peptide"
] | Pending | 948,326,400,000 | [
[
{
"name": "Obstetric Labor, Premature",
"lang": "EN"
},
{
"name": "早产",
"lang": "CN"
}
]
] | [
"China",
"European Union",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "塞普替尼",
"lang": "CN"
},
{
"name": "Selpercatinib",
"lang": "EN"
},
{
"name": "セルペルカチニブ",
"lang": "JP"
}
] | [
{
"name": "RETEVMOTM",
"lang": "EN"
},
{
"name": "Selpercatinib (JAN/USAN/INN)",
"lang": "EN"
},
{
"name": "塞尔帕替尼",
"lang": "CN"
}
] | [
[
{
"name": "Tyrosine-protein kinase receptor RET",
"lang": "EN"
},
{
"name": "酪氨酸蛋白激酶受体RET",
"lang": "CN"
}
]
] | [
[
{
"name": "RET fusion-positive Solid Tumors",
"lang": "EN"
},
{
"name": "RET融合阳性实体瘤",
"lang": "CN"
}
],
[
{
"name": "metastatic non-small cell lung cancer",
"lang": "EN"
},
{
"name": "转移性非小细胞肺癌",
"lang": "CN"
}
],
[
{
... | [
"Small molecule drug"
] | Phase 3 Clinical | 1,588,896,000,000 | [
[
{
"name": "Non-Small Cell Lung Cancer",
"lang": "EN"
},
{
"name": "非小细胞肺癌",
"lang": "CN"
}
],
[
{
"name": "RET Mutation-Positive Medullary Thyroid Cancer",
"lang": "EN"
},
{
"name": "RET突变阳性甲状腺髓样癌",
"lang": "CN"
}
],
[
{
... | [
"United States",
"China",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "哌柏西利",
"lang": "CN"
},
{
"name": "Palbociclib",
"lang": "EN"
},
{
"name": "パルボシクリブ",
"lang": "JP"
}
] | [
{
"name": "Iburance",
"lang": "EN"
},
{
"name": "Palbociclib (JAN/USAN)",
"lang": "EN"
},
{
"name": "Palbociclib Isethionate",
"lang": "EN"
},
{
"name": "Parvociclib",
"lang": "EN"
},
{
"name": "帕博西尼",
"lang": "CN"
},
{
"name": "羟乙磺酸哌柏西利",
"lang": ... | [
[
{
"name": "Cyclin-dependent kinase 4",
"lang": "EN"
},
{
"name": "细胞周期蛋白依赖性激酶4",
"lang": "CN"
}
],
[
{
"name": "Cyclin-dependent kinase 6",
"lang": "EN"
},
{
"name": "细胞周期蛋白依赖性激酶6",
"lang": "CN"
}
]
] | [
[
{
"name": "Breast cancer recurrent",
"lang": "EN"
},
{
"name": "复发性乳腺癌",
"lang": "CN"
}
],
[
{
"name": "Hormone receptor positive HER2 negative breast cancer",
"lang": "EN"
},
{
"name": "HR阳性/HER2阴性乳腺癌",
"lang": "CN"
}
],
[
... | [
"Small molecule drug"
] | Suspended | 1,422,921,600,000 | [
[
{
"name": "ER-positive/HER2-negative Breast Cancer",
"lang": "EN"
},
{
"name": "ER阳性/HER2阴性乳腺癌",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Japan",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "琥珀酸索利那新/盐酸坦洛新",
"lang": "CN"
},
{
"name": "Solifenacin Succinate/Tamsulosin Hydrochloride",
"lang": "EN"
}
] | null | [
[
{
"name": "Muscarinic acetylcholine receptor M3",
"lang": "EN"
},
{
"name": "毒蕈碱型乙酰胆碱受体M3",
"lang": "CN"
}
],
[
{
"name": "Alpha-1a adrenergic receptor",
"lang": "EN"
},
{
"name": "肾上腺素能受体α-1a",
"lang": "CN"
}
]
] | [
[
{
"name": "Urination Disorders",
"lang": "EN"
},
{
"name": "排尿障碍",
"lang": "CN"
}
],
[
{
"name": "Lower Urinary Tract Symptoms",
"lang": "EN"
},
{
"name": "下尿路症状",
"lang": "CN"
}
],
[
{
"name": "Prostatic Hyperplasia... | [
"Small molecule drug"
] | Phase 3 Clinical | 1,381,104,000,000 | [
[
{
"name": "Lower Urinary Tract Symptoms",
"lang": "EN"
},
{
"name": "下尿路症状",
"lang": "CN"
}
]
] | [
"South Korea",
"Netherlands"
] |
[
{
"name": "艾可瑞妥单抗",
"lang": "CN"
},
{
"name": "Epcoritamab",
"lang": "EN"
},
{
"name": "エプコリタマブ(遺伝子組換え)",
"lang": "JP"
}
] | [
{
"name": "Anti-CD3 anti-CD20 bispecific antibody",
"lang": "EN"
},
{
"name": "Anti-CD3 anti-CD20 bispecific antibody(Genmab A/S)",
"lang": "EN"
},
{
"name": "epcoritamab-bysp",
"lang": "EN"
},
{
"name": "依普利他单抗",
"lang": "CN"
},
{
"name": "艾普妥单抗",
"lang": "CN... | [
[
{
"name": "B-lymphocyte antigen CD20",
"lang": "EN"
},
{
"name": "B淋巴细胞抗原CD20",
"lang": "CN"
}
],
[
{
"name": "T cell surface glycoprotein CD3",
"lang": "EN"
},
{
"name": "T细胞表面糖蛋白CD3复合体",
"lang": "CN"
}
]
] | [
[
{
"name": "Large B-cell lymphoma",
"lang": "EN"
},
{
"name": "大B细胞淋巴瘤",
"lang": "CN"
}
],
[
{
"name": "Recurrent Grade 3b Follicular Lymphoma",
"lang": "EN"
},
{
"name": "复发性 3b 级滤泡性淋巴瘤",
"lang": "CN"
}
],
[
{
"name"... | [
"Bispecific T-cell Engager (BiTE)"
] | Approved | 1,684,454,400,000 | [
[
{
"name": "Diffuse Large B-Cell Lymphoma",
"lang": "EN"
},
{
"name": "弥漫性大B细胞淋巴瘤",
"lang": "CN"
}
],
[
{
"name": "High grade B-cell lymphoma",
"lang": "EN"
},
{
"name": "高级别B细胞淋巴瘤",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Japan",
"United Kingdom",
"Canada",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "瑞卡西单抗",
"lang": "CN"
},
{
"name": "Recaticimab",
"lang": "EN"
}
] | null | [
[
{
"name": "Proprotein convertase subtilisin kexin type 9",
"lang": "EN"
},
{
"name": "前蛋白转化酶枯草杆菌蛋白酶Kexin-9",
"lang": "CN"
}
]
] | [
[
{
"name": "Complex dyslipidemia",
"lang": "EN"
},
{
"name": "复杂性血脂异常",
"lang": "CN"
}
],
[
{
"name": "Hypercholesterolemia",
"lang": "EN"
},
{
"name": "高胆固醇血症",
"lang": "CN"
}
],
[
{
"name": "Primary hypercholesterol... | [
"Monoclonal antibody"
] | Pending | 1,736,294,400,000 | [
[
{
"name": "Primary hypercholesterolemia",
"lang": "EN"
},
{
"name": "原发性高胆固醇血症",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "依奇珠单抗",
"lang": "CN"
},
{
"name": "Ixekizumab",
"lang": "EN"
},
{
"name": "イキセキズマブ（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "Ixekizumab (Genetical Recombination)",
"lang": "EN"
},
{
"name": "Ixekizumab (USAN)",
"lang": "EN"
},
{
"name": "Ixekizumab (genetical recombination) (JAN)",
"lang": "EN"
},
{
"name": "伊克珠单抗",
"lang": "CN"
}
] | [
[
{
"name": "Interleukin 17A",
"lang": "EN"
},
{
"name": "白细胞介素-17A",
"lang": "CN"
}
]
] | [
[
{
"name": "Spondylarthritis",
"lang": "EN"
},
{
"name": "脊椎关节炎",
"lang": "CN"
}
],
[
{
"name": "Erythrodermic psoriasis",
"lang": "EN"
},
{
"name": "红皮病性银屑病",
"lang": "CN"
}
],
[
{
"name": "Psoriasis",
"lang": ... | [
"Monoclonal antibody"
] | NDA/BLA | 1,458,604,800,000 | [
[
{
"name": "Plaque psoriasis",
"lang": "EN"
},
{
"name": "斑块状银屑病",
"lang": "CN"
}
]
] | [
"United States",
"China",
"European Union",
"Japan",
"Canada",
"Australia",
"Switzerland",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "替米沙坦/S-氨氯地平烟酸酯/氯噻酮",
"lang": "CN"
},
{
"name": "Telmisartan/S-Amlodipine Nicotinate/Chlorthalidone",
"lang": "EN"
}
] | null | [
[
{
"name": "Angiotensin II Receptor Type 1",
"lang": "EN"
},
{
"name": "血管紧张素II-1型受体",
"lang": "CN"
}
],
[
{
"name": "Thiazide-sensitive sodium-chloride cotransporter",
"lang": "EN"
},
{
"name": "噻嗪类敏感氯化钠协同转运蛋白",
"lang": "CN"
}
]... | [
[
{
"name": "Essential Hypertension",
"lang": "EN"
},
{
"name": "原发性高血压",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Approved | 1,761,609,600,000 | [
[
{
"name": "Essential Hypertension",
"lang": "EN"
},
{
"name": "原发性高血压",
"lang": "CN"
}
]
] | [
"South Korea"
] |
[
{
"name": "盐酸他喷他多",
"lang": "CN"
},
{
"name": "Tapentadol Hydrochloride",
"lang": "EN"
},
{
"name": "タペンタドール塩酸塩",
"lang": "JP"
}
] | [
{
"name": "TAPENTADOL",
"lang": "EN"
},
{
"name": "Tapentadol",
"lang": "EN"
},
{
"name": "Tapentadol hydrochloride (JAN)",
"lang": "EN"
}
] | [
[
{
"name": "Norepinephrine transporter",
"lang": "EN"
},
{
"name": "去甲肾上腺素转运蛋白",
"lang": "CN"
}
],
[
{
"name": "Mu opioid receptor",
"lang": "EN"
},
{
"name": "μ-阿片受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Cancer Pain",
"lang": "EN"
},
{
"name": "癌症疼痛",
"lang": "CN"
}
],
[
{
"name": "Neuralgia",
"lang": "EN"
},
{
"name": "神经痛",
"lang": "CN"
}
],
[
{
"name": "Chronic Pain",
"lang": "EN"
},
{
... | [
"Small molecule drug"
] | Discontinued | 1,227,139,200,000 | [
[
{
"name": "Acute Pain",
"lang": "EN"
},
{
"name": "急性疼痛",
"lang": "CN"
}
]
] | [
"United States",
"Japan",
"United Kingdom",
"Australia",
"Austria",
"Belgium",
"Cyprus",
"Czechia",
"Germany",
"Denmark",
"Spain",
"Greece",
"Croatia",
"Ireland",
"Italy",
"Luxembourg",
"Netherlands",
"Norway",
"Poland",
"Portugal",
"Sweden",
"Slovenia",
"Slovakia"
] |
[
{
"name": "考比司他",
"lang": "CN"
},
{
"name": "Cobicistat",
"lang": "EN"
}
] | [
{
"name": "Cobicistat (JAN/USAN/INN)",
"lang": "EN"
},
{
"name": "cobicistat on silicon dioxide",
"lang": "EN"
}
] | [
[
{
"name": "Cytochrome P450 3A4",
"lang": "EN"
},
{
"name": "细胞色素P450家族成员3A4",
"lang": "CN"
}
],
[
{
"name": "cytochrome P450 family 3 subfamily A member 5",
"lang": "EN"
}
],
[
{
"name": "cytochrome P450 family 3 subfamily A member 7",
... | [
[
{
"name": "HIV Infections",
"lang": "EN"
},
{
"name": "HIV感染",
"lang": "CN"
}
],
[
{
"name": "Acquired Immunodeficiency Syndrome",
"lang": "EN"
},
{
"name": "获得性免疫缺陷综合征",
"lang": "CN"
}
],
[
{
"name": "Solid tumor",
... | [
"Small molecule drug"
] | Pending | 1,379,548,800,000 | [
[
{
"name": "HIV Infections",
"lang": "EN"
},
{
"name": "HIV感染",
"lang": "CN"
}
]
] | [
"European Union",
"Australia",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "人凝血因子VIII（山西康宝生物制品股份有限公司）",
"lang": "CN"
},
{
"name": "Factor VIII(Shanxi Kangbao Biological Products)",
"lang": "EN"
}
] | null | [
[
{
"name": "Coagulation factor X",
"lang": "EN"
},
{
"name": "凝血因子X",
"lang": "CN"
}
]
] | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
]
] | [
"Non-recombinant coagulation factor"
] | Approved | 1,597,190,400,000 | [
[
{
"name": "Hemophilia A",
"lang": "EN"
},
{
"name": "血友病A",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "Ponesimod",
"lang": "EN"
}
] | [
{
"name": "Ponesimod (USAN/INN)",
"lang": "EN"
}
] | [
[
{
"name": "Sphingosine 1-phosphate receptor Edg-1",
"lang": "EN"
},
{
"name": "鞘氨醇-1-磷酸受体-Edg-1",
"lang": "CN"
}
]
] | [
[
{
"name": "Multiple sclerosis relapse",
"lang": "EN"
},
{
"name": "复发性多发性硬化",
"lang": "CN"
}
],
[
{
"name": "Plaque psoriasis",
"lang": "EN"
},
{
"name": "斑块状银屑病",
"lang": "CN"
}
],
[
{
"name": "Colitis, Ulcerative",... | [
"Small molecule drug"
] | Phase 3 Clinical | 1,616,025,600,000 | [
[
{
"name": "Multiple sclerosis relapse",
"lang": "EN"
},
{
"name": "复发性多发性硬化",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Canada",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "甲泼尼龙",
"lang": "CN"
},
{
"name": "Methylprednisolone",
"lang": "EN"
},
{
"name": "メチルプレドニゾロン",
"lang": "JP"
}
] | [
{
"name": "(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione",
"lang": "EN"
},
{
"name": "1-dehydro-6α-methylhydrocortisone",
"lang": "EN"
},
{
"name": "6α-methyl-11β,17α,21-triol-1,4-pregnadiene-3,20-dione",
"lang": "EN"
},
{
"name": "Methylprednisolone (JP17/... | [
[
{
"name": "Glucocorticoid receptor",
"lang": "EN"
},
{
"name": "糖皮质激素受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Multiple Sclerosis",
"lang": "EN"
},
{
"name": "多发性硬化症",
"lang": "CN"
}
],
[
{
"name": "Anaphylaxis",
"lang": "EN"
},
{
"name": "过敏反应",
"lang": "CN"
}
],
[
{
"name": "Collagen Diseases",
"lang": "EN"... | [
"Small molecule drug"
] | Phase 1 Clinical | -384,652,800,000 | [
[
{
"name": "Anaphylaxis",
"lang": "EN"
},
{
"name": "过敏反应",
"lang": "CN"
}
],
[
{
"name": "Collagen Diseases",
"lang": "EN"
},
{
"name": "胶原蛋白疾病",
"lang": "CN"
}
],
[
{
"name": "Edema",
"lang": "EN"
},
{... | [
"United States",
"China",
"Japan"
] |
[
{
"name": "溴夫定",
"lang": "CN"
},
{
"name": "Brivudine",
"lang": "EN"
}
] | [
{
"name": "(E)-5-(2-Bromovinyl)-deoxyuridine",
"lang": "EN"
},
{
"name": "BVdU",
"lang": "EN"
},
{
"name": "Brivudine (INN)",
"lang": "EN"
}
] | [
[
{
"name": "DNA-directed DNA polymerase",
"lang": "EN"
},
{
"name": "DNA-指导DNA聚合酶",
"lang": "CN"
}
],
[
{
"name": "Thymidylate synthase",
"lang": "EN"
},
{
"name": "胸苷酸合成酶",
"lang": "CN"
}
]
] | [
[
{
"name": "Varicella Zoster Virus Infection",
"lang": "EN"
},
{
"name": "水痘带状疱疹病毒感染",
"lang": "CN"
}
],
[
{
"name": "Pancreatic Cancer",
"lang": "EN"
},
{
"name": "胰腺癌",
"lang": "CN"
}
],
[
{
"name": "Infectious Dise... | [
"Small molecule drug"
] | Discontinued | 1,015,286,400,000 | [
[
{
"name": "Varicella Zoster Virus Infection",
"lang": "EN"
},
{
"name": "水痘带状疱疹病毒感染",
"lang": "CN"
}
]
] | [
"Austria",
"Belgium",
"Germany",
"Spain",
"Greece",
"Italy",
"Luxembourg",
"Portugal"
] |
[
{
"name": "羟丁酸钠/羟丁酸钾/羟丁酸钙/羟丁酸镁",
"lang": "CN"
},
{
"name": "Sodium Oxybate/Potassium Oxybate/Calcium Oxybate/Magnesium Oxybate",
"lang": "EN"
}
] | [
{
"name": "LXB",
"lang": "EN"
},
{
"name": "Oxybate mixed salt",
"lang": "EN"
}
] | [
[
{
"name": "Gamma-Aminobutyric Acid B Receptor",
"lang": "EN"
},
{
"name": "γ-氨基丁酸B受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Idiopathic Hypersomnia",
"lang": "EN"
},
{
"name": "特发性睡眠过度",
"lang": "CN"
}
],
[
{
"name": "Cataplexy",
"lang": "EN"
},
{
"name": "猝倒症",
"lang": "CN"
}
],
[
{
"name": "Narcolepsy",
"lang": "EN"
... | [
"Small molecule drug"
] | Approved | 1,595,289,600,000 | [
[
{
"name": "Cataplexy",
"lang": "EN"
},
{
"name": "猝倒症",
"lang": "CN"
}
],
[
{
"name": "Narcolepsy",
"lang": "EN"
},
{
"name": "发作性睡病",
"lang": "CN"
}
]
] | [
"United States",
"Canada"
] |
[
{
"name": "酒石酸托特罗定",
"lang": "CN"
},
{
"name": "Tolterodine Tartrate",
"lang": "EN"
},
{
"name": "トルテロジン酒石酸塩",
"lang": "JP"
}
] | [
{
"name": "Detrol",
"lang": "EN"
},
{
"name": "Detrol LA",
"lang": "EN"
},
{
"name": "Detrusitol SR",
"lang": "EN"
},
{
"name": "Detrusitol XL",
"lang": "EN"
},
{
"name": "Tolterodine",
"lang": "EN"
},
{
"name": "Tolterodine L-Tartrate",
"lang": "E... | [
[
{
"name": "Muscarinic acetylcholine receptor M2",
"lang": "EN"
},
{
"name": "毒蕈碱型乙酰胆碱受体M2",
"lang": "CN"
}
],
[
{
"name": "Muscarinic acetylcholine receptor M3",
"lang": "EN"
},
{
"name": "毒蕈碱型乙酰胆碱受体M3",
"lang": "CN"
}
]
] | [
[
{
"name": "Urinary Bladder, Overactive",
"lang": "EN"
},
{
"name": "膀胱过度活动症",
"lang": "CN"
}
],
[
{
"name": "Urinary Incontinence",
"lang": "EN"
},
{
"name": "尿失禁",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Pending | 882,835,200,000 | [
[
{
"name": "Urinary Bladder, Overactive",
"lang": "EN"
},
{
"name": "膀胱过度活动症",
"lang": "CN"
}
]
] | [
"United States",
"China",
"Japan",
"United Kingdom",
"Australia",
"Austria",
"Belgium",
"Germany",
"Finland",
"France",
"Ireland",
"Italy",
"Luxembourg",
"Malta",
"Netherlands",
"Sweden"
] |
[
{
"name": "沙西妥昔单抗",
"lang": "CN"
},
{
"name": "Cetuximab Sarotalocan Sodium (Genetical Recombination)",
"lang": "EN"
},
{
"name": "セツキシマブ サロタロカンナトリウム（遺伝子組換え）",
"lang": "JP"
}
] | [
{
"name": "Cetuximab Sarotalocan",
"lang": "EN"
},
{
"name": "Cetuximab sarotalocan",
"lang": "EN"
},
{
"name": "Cetuximab-IR700",
"lang": "EN"
},
{
"name": "cetuximab saratolacan",
"lang": "EN"
}
] | [
[
{
"name": "Epidermal growth factor receptor erbB1",
"lang": "EN"
},
{
"name": "表皮生长因子受体erbB1",
"lang": "CN"
}
]
] | [
[
{
"name": "Head and Neck Neoplasms",
"lang": "EN"
},
{
"name": "头颈部肿瘤",
"lang": "CN"
}
],
[
{
"name": "Recurrent Head and Neck Carcinoma",
"lang": "EN"
},
{
"name": "复发性头颈癌",
"lang": "CN"
}
],
[
{
"name": "Recurrent ... | [
"Antibody-photosensitizer conjugates"
] | Phase 1/2 Clinical | 1,600,992,000,000 | [
[
{
"name": "Head and Neck Neoplasms",
"lang": "EN"
},
{
"name": "头颈部肿瘤",
"lang": "CN"
}
]
] | [
"Japan"
] |
[
{
"name": "盐酸妥诺达非",
"lang": "CN"
},
{
"name": "Tononadif Hydrochloride",
"lang": "EN"
}
] | [
{
"name": "Ecocarbamate hydrochloride",
"lang": "EN"
},
{
"name": "Gluconocin hydrochloride",
"lang": "EN"
},
{
"name": "Tunodafil",
"lang": "EN"
},
{
"name": "Yonkenafil",
"lang": "EN"
},
{
"name": "盐酸优克那非",
"lang": "CN"
}
] | [
[
{
"name": "Phosphodiesterase 5A",
"lang": "EN"
},
{
"name": "磷酸二酯酶-5A",
"lang": "CN"
}
]
] | [
[
{
"name": "Erectile Dysfunction",
"lang": "EN"
},
{
"name": "勃起功能障碍",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Approved | 1,753,142,400,000 | [
[
{
"name": "Erectile Dysfunction",
"lang": "EN"
},
{
"name": "勃起功能障碍",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "奥格列龙",
"lang": "CN"
},
{
"name": "Orforglipron",
"lang": "EN"
}
] | [
{
"name": "GLP-1R NPA",
"lang": "EN"
},
{
"name": "Orforglipron calcium",
"lang": "EN"
},
{
"name": "奥氟格列隆",
"lang": "CN"
},
{
"name": "奥福格列酮",
"lang": "CN"
},
{
"name": "奥福格利普隆",
"lang": "CN"
},
{
"name": "奥福鲁肽",
"lang": "CN"
}
] | [
[
{
"name": "Glucagon-like peptide 1 receptor",
"lang": "EN"
},
{
"name": "胰高血糖素样肽-1受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Obesity",
"lang": "EN"
},
{
"name": "肥胖",
"lang": "CN"
}
],
[
{
"name": "Overweight",
"lang": "EN"
},
{
"name": "超重",
"lang": "CN"
}
],
[
{
"name": "Diabetes Mellitus",
"lang": "EN"
},
{
... | [
"Small molecule drug"
] | Phase 3 Clinical | 1,775,001,600,000 | [
[
{
"name": "Obesity",
"lang": "EN"
},
{
"name": "肥胖",
"lang": "CN"
}
],
[
{
"name": "Overweight",
"lang": "EN"
},
{
"name": "超重",
"lang": "CN"
}
]
] | [
"United States"
] |
[
{
"name": "硫酸奎尼丁",
"lang": "CN"
},
{
"name": "Quinidine Sulfate",
"lang": "EN"
},
{
"name": "キニジン硫酸塩水和物",
"lang": "JP"
}
] | [
{
"name": "(+)-quinidine",
"lang": "EN"
},
{
"name": "(8R,9S)-Quinidine",
"lang": "EN"
},
{
"name": "(R)-(6-Methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol",
"lang": "EN"
},
{
"name": "(S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-... | [
[
{
"name": "Sodium voltage-gated channel alpha subunits",
"lang": "EN"
},
{
"name": "电压门控钠通道α亚基家族",
"lang": "CN"
}
]
] | [
[
{
"name": "Arrhythmias, Cardiac",
"lang": "EN"
},
{
"name": "心律失常",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Withdrawn | -248,054,400,000 | [
[
{
"name": "Arrhythmias, Cardiac",
"lang": "EN"
},
{
"name": "心律失常",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "去纤苷钠",
"lang": "CN"
},
{
"name": "Defibrotide Sodium",
"lang": "EN"
},
{
"name": "デフィブロチドナトリウム",
"lang": "JP"
}
] | [
{
"name": "Defibrotide free acid",
"lang": "EN"
},
{
"name": "Defibrotide free acid (porcine mucosa)",
"lang": "EN"
},
{
"name": "Defibrotide free acid (porcine)",
"lang": "EN"
},
{
"name": "Defibrotide sodium (JAN/USAN)",
"lang": "EN"
},
{
"name": "Fraction P",
... | [
[
{
"name": "Plasminogen activator inhibitor 1",
"lang": "EN"
},
{
"name": "纤维蛋白溶酶原激活质抑制物-1",
"lang": "CN"
}
],
[
{
"name": "plasminogen activator, tissue type",
"lang": "EN"
}
],
[
{
"name": "Von willebrand factor",
"lang": "EN"
... | [
[
{
"name": "Venoocclusive disease",
"lang": "EN"
},
{
"name": "静脉闭塞性疾病",
"lang": "CN"
}
],
[
{
"name": "Hepatic Veno-Occlusive Disease",
"lang": "EN"
},
{
"name": "肝静脉闭塞性疾病",
"lang": "CN"
}
],
[
{
"name": "COVID-19",
... | [
"Nucleic acid drugs"
] | Phase 2 Clinical | 1,382,054,400,000 | [
[
{
"name": "Hepatic Veno-Occlusive Disease",
"lang": "EN"
},
{
"name": "肝静脉闭塞性疾病",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Japan",
"Canada",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "纳武利尤单抗/透明质酸酶",
"lang": "CN"
},
{
"name": "Nivolumab/Hyaluronidase-nvhy",
"lang": "EN"
}
] | null | [
[
{
"name": "Hyaluronic acid",
"lang": "EN"
},
{
"name": "透明质酸",
"lang": "CN"
}
],
[
{
"name": "Programmed cell death protein 1",
"lang": "EN"
},
{
"name": "细胞程序性死亡-1",
"lang": "CN"
}
]
] | [
[
{
"name": "Adenocarcinoma of Esophagus",
"lang": "EN"
},
{
"name": "食管腺癌",
"lang": "CN"
}
],
[
{
"name": "Colorectal Cancer",
"lang": "EN"
},
{
"name": "结直肠癌",
"lang": "CN"
}
],
[
{
"name": "Esophageal Carcinoma",
... | [
"Monoclonal antibody",
"Enzyme"
] | Approved | 1,735,257,600,000 | [
[
{
"name": "Adenocarcinoma of Esophagus",
"lang": "EN"
},
{
"name": "食管腺癌",
"lang": "CN"
}
],
[
{
"name": "Colorectal Cancer",
"lang": "EN"
},
{
"name": "结直肠癌",
"lang": "CN"
}
],
[
{
"name": "Esophageal Carcinoma",
... | [
"United States"
] |
[
{
"name": "盐酸羟考酮",
"lang": "CN"
},
{
"name": "Oxycodone Hydrochloride",
"lang": "EN"
},
{
"name": "オキシコドン塩酸塩水和物",
"lang": "JP"
}
] | [
{
"name": "Oxycodone Hydrochloride Hydrate",
"lang": "EN"
},
{
"name": "Oxycodone hydrochloride (USP)",
"lang": "EN"
}
] | [
[
{
"name": "Opioid receptors",
"lang": "EN"
},
{
"name": "阿片样受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Cancer Pain",
"lang": "EN"
},
{
"name": "癌症疼痛",
"lang": "CN"
}
],
[
{
"name": "Chronic Pain",
"lang": "EN"
},
{
"name": "慢性疼痛",
"lang": "CN"
}
],
[
{
"name": "Pain",
"lang": "EN"
},
{
"... | [
"Small molecule drug"
] | Discontinued | 909,360,000,000 | [
[
{
"name": "Pain",
"lang": "EN"
},
{
"name": "疼痛",
"lang": "CN"
}
]
] | [
"United States",
"China",
"Japan"
] |
[
{
"name": "去羟肌苷",
"lang": "CN"
},
{
"name": "Didanosine",
"lang": "EN"
}
] | [
{
"name": "2,3-Dideoxyinosine",
"lang": "EN"
},
{
"name": "9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one",
"lang": "EN"
},
{
"name": "9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one",
"lang": "EN"
},
{
"name": "9-((2S,5R)-5-Hy... | [
[
{
"name": "Viral reverse transcriptase",
"lang": "EN"
},
{
"name": "逆转录酶",
"lang": "CN"
}
]
] | [
[
{
"name": "HIV Infections",
"lang": "EN"
},
{
"name": "HIV感染",
"lang": "CN"
}
],
[
{
"name": "Acquired Immunodeficiency Syndrome",
"lang": "EN"
},
{
"name": "获得性免疫缺陷综合征",
"lang": "CN"
}
],
[
{
"name": "AIDS-Related C... | [
"Small molecule drug"
] | Pending | 686,966,400,000 | [
[
{
"name": "HIV Infections",
"lang": "EN"
},
{
"name": "HIV感染",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "Etuvetidigene autotemcel",
"lang": "EN"
}
] | [
{
"name": "WAS gene therapy",
"lang": "EN"
},
{
"name": "WAS transduced CD34+ stem cells",
"lang": "EN"
},
{
"name": "WAS transduced autologous CD34+ stem cells",
"lang": "EN"
},
{
"name": "autologous CD34+ haematopoietic stem cells transduced ex vivo with a lentiviral vector... | [
[
{
"name": "Wiskott-Aldrich syndrome protein",
"lang": "EN"
},
{
"name": "Wiskott-Aldrich综合征蛋白",
"lang": "CN"
}
]
] | [
[
{
"name": "Wiskott-Aldrich Syndrome",
"lang": "EN"
},
{
"name": "Wiskott-Aldrich综合征",
"lang": "CN"
}
]
] | [
"Gene therapy",
"Hematopoietic stem cell therapy"
] | Approved | 1,765,267,232,411 | [
[
{
"name": "Wiskott-Aldrich Syndrome",
"lang": "EN"
},
{
"name": "Wiskott-Aldrich综合征",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Iceland",
"Liechtenstein",
"Norway"
] |
[
{
"name": "盐酸丙美卡因",
"lang": "CN"
},
{
"name": "Proparacaine Hydrochloride",
"lang": "EN"
}
] | [
{
"name": "Proparacaine hydrochloride (USP)",
"lang": "EN"
},
{
"name": "Proxymetacaine",
"lang": "EN"
}
] | [
[
{
"name": "Sodium voltage-gated channel alpha subunits",
"lang": "EN"
},
{
"name": "电压门控钠通道α亚基家族",
"lang": "CN"
}
]
] | [
[
{
"name": "Anesthesia",
"lang": "EN"
},
{
"name": "麻醉",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Withdrawn | -520,819,200,000 | [
[
{
"name": "Anesthesia",
"lang": "EN"
},
{
"name": "麻醉",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "纳基奥仑赛",
"lang": "CN"
},
{
"name": "Inaticabtagene Autoleucel",
"lang": "EN"
}
] | [
{
"name": "Anti-CD19 CAR-T cell therapy (Heyuan Biotech)",
"lang": "EN"
},
{
"name": "Anti-CD19 Chimeric Antigen Receptor T-Cell Injection (Juventas Cell)",
"lang": "EN"
},
{
"name": "Nachiotaxel",
"lang": "EN"
},
{
"name": "抗CD19嵌合抗原受体T细胞 (CAR-T)疗法 (天津合源生物)",
"lang": "CN... | [
[
{
"name": "B-lymphocyte antigen CD19",
"lang": "EN"
},
{
"name": "B淋巴细胞抗原CD19",
"lang": "CN"
}
]
] | [
[
{
"name": "Large B-cell lymphoma",
"lang": "EN"
},
{
"name": "大B细胞淋巴瘤",
"lang": "CN"
}
],
[
{
"name": "Refractory B Acute Lymphoblastic Leukemia",
"lang": "EN"
},
{
"name": "难治性 B 细胞急性淋巴细胞白血病",
"lang": "CN"
}
],
[
{
... | [
"Autologous CAR-T"
] | Phase 2 Clinical | 1,699,315,200,000 | [
[
{
"name": "Recurrent B Acute Lymphoblastic Leukemia",
"lang": "EN"
},
{
"name": "复发性 B 细胞急性淋巴细胞白血病",
"lang": "CN"
}
]
] | [
"China"
] |
[
{
"name": "茶苯海明/维生素B6",
"lang": "CN"
},
{
"name": "Dimenhydrinate/Pyridoxine Hydrochloride",
"lang": "EN"
}
] | null | [
[
{
"name": "Histamine H1 receptor",
"lang": "EN"
},
{
"name": "组胺H1受体",
"lang": "CN"
}
]
] | [
[
{
"name": "Motion Sickness",
"lang": "EN"
},
{
"name": "晕动病",
"lang": "CN"
}
]
] | [
"Small molecule drug"
] | Approved | 1,721,865,600,000 | [
[
{
"name": "Motion Sickness",
"lang": "EN"
},
{
"name": "晕动病",
"lang": "CN"
}
]
] | [
"South Korea"
] |
[
{
"name": "盐酸特泊替尼",
"lang": "CN"
},
{
"name": "Tepotinib Hydrochloride Hydrate",
"lang": "EN"
},
{
"name": "テポチニブ塩酸塩水和物",
"lang": "JP"
}
] | [
{
"name": "Tepotinib",
"lang": "EN"
},
{
"name": "Tepotinib Hydrochloride(USAN)",
"lang": "EN"
}
] | [
[
{
"name": "Hepatocyte growth factor receptor",
"lang": "EN"
},
{
"name": "肝细胞生长因子受体",
"lang": "CN"
}
]
] | [
[
{
"name": "MET Exon 14 Skipping Mutation Non-small Cell Lung Cancer",
"lang": "EN"
},
{
"name": "MET外显子14跳变的非小细胞肺癌",
"lang": "CN"
}
],
[
{
"name": "Non-Small Cell Lung Cancer",
"lang": "EN"
},
{
"name": "非小细胞肺癌",
"lang": "CN"
}
... | [
"Small molecule drug"
] | Pending | 1,585,094,400,000 | [
[
{
"name": "c-Met positive non-small cell lung cancer",
"lang": "EN"
},
{
"name": "c-Met阳性非小细胞肺癌",
"lang": "CN"
}
]
] | [
"United States",
"European Union",
"Japan",
"Australia",
"Iceland",
"South Korea",
"Liechtenstein",
"Norway"
] |
[
{
"name": "氢溴酸吡西替尼",
"lang": "CN"
},
{
"name": "Peficitinib Hydrobromide",
"lang": "EN"
},
{
"name": "ペフィシチニブ臭化水素酸塩",
"lang": "JP"
}
] | [
{
"name": "ASP-015K hydrobromide",
"lang": "EN"
},
{
"name": "Peficitinib",
"lang": "EN"
},
{
"name": "Peficitinib hydrobromide (JAN/USAN)",
"lang": "EN"
},
{
"name": "佩非替尼",
"lang": "CN"
}
] | [
[
{
"name": "Tyrosine-protein kinase JAK1",
"lang": "EN"
},
{
"name": "酪氨酸蛋白激酶JAK1",
"lang": "CN"
}
],
[
{
"name": "Tyrosine-protein kinase JAK2",
"lang": "EN"
},
{
"name": "酪氨酸蛋白激酶JAK2",
"lang": "CN"
}
],
[
{
"name": ... | [
[
{
"name": "Rheumatoid Arthritis",
"lang": "EN"
},
{
"name": "类风湿关节炎",
"lang": "CN"
}
],
[
{
"name": "Colitis, Ulcerative",
"lang": "EN"
},
{
"name": "溃疡性结肠炎",
"lang": "CN"
}
],
[
{
"name": "Plaque psoriasis",
"... | [
"Small molecule drug"
] | Pending | 1,553,558,400,000 | [
[
{
"name": "Rheumatoid Arthritis",
"lang": "EN"
},
{
"name": "类风湿关节炎",
"lang": "CN"
}
]
] | [
"China",
"Japan",
"South Korea"
] |
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