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phasepure bicuose which is isostructural to the layered ptype transparent conductor lacuos has been synthesized in high yield by a singlestep hydrothermal reaction at LT degrees c and pressure atm a moderate reaction temperature of degrees c was sufficiently high to solubilize both bio and cuo and stabilize monovalent ... | 24 | low temperature |
two racemic atropisomeric nnchelate ligands bisnphpyindolyl and bisnnpyindolylphenylpyindolyl have been found to be able to distinguish the enantiomers of znrbrmebu and znsbrmebu where brmebu occhbrchme with a distinct and intense cd spectral response at approximately the microm concentration range computational studie... | 115|132|150|154|164|176 | binding|model|groups|fluorescent|fluorescent|binding |
the dehydrogenation of ammonia borane ab and methylammonia borane meab is shown to be catalyzed by several ruamido complexes up to equiv of h system wt is released from ab by as little as mol ru within min and up to equiv of h system wt are released from meab with mol ru in under min at RT the first equivalent emerging... | 57 | room temperature |
disulfiderich peptides represent a megadiverse group of natural products with very promising therapeutic potential to accelerate their functional characterization highthroughput chemical synthesis and folding methods are required including efficient mapping of multiple disulfide bridges here we describe a novel RPA for... | 39 | approach |
chiral mesoporous materials have been prepared with purely organic monomers employing an enantiomerically pure biphenyl bissiloxane as a dopant along with simple bistriethoxysilylbiphenyl as the bulk material analysis of these materials by cd spectroscopy indicates the formation of new chiral aggregates in the solid st... | 63 | biphenyl |
a novel class of derivatized acetylacetonate acac linkers for robust functionalization of tio NPs nps under AQ and oxidative conditions is reported the resulting surface adsorbate anchors are particularly relevant to engineering photocatalytic and photovoltaic devices since they can be applied to attach a broad range o... | 13|16|91|162 | nanoparticles|aqueous|effective|injection |
the unique symmetry properties of second harmonic generation shg microscopy enabled CS and selective imaging of protein microcrystals with negligible contributions from solvated proteins or amorphous protein aggregates in studies of microcrystallites of green FL protein gfp prepared in pl droplets the shg intensities r... | 11|34|85|100 | sensitive|fluorescent|detection limits|sensitive |
the first electrophilic pdiicatalyzed allylic c h alkylation is reported providing a novel method for formation of spsp c c bonds directly from c h bonds a wide range of aromatic and heteroaromatic linear ealphanitroarylpentenoates are obtained as single olefin isomers in excellent yields directly from terminal olefin ... | 92 | enriched |
highthroughput screening of national CA institute libraries of synthetic and NK EDC identified the vinylogous ureas aminotetrahydro hcyclohepta bthiophenecarboxamide nsc and naminocarbonyldimethylthienylfurancarboxamide nsc as inhibitors of the ribonuclease h rnase h activity of hiv and hiv reverse transcriptase rt a y... | 4|10|11 | cancer|natural|compounds |
samples of spanish virgin olive oils voos from different categories origins varieties and commercial brands were analyzed by hplc with a programmable fluorescence detector to determine the content of nine heavy polycyclic aromatic hydrocarbons pahs benzoaanthracene chrysene benzoepyrene benzobfluoranthene benzokfluoran... | 40|66|118 | benzoapyrene|european union|benzoapyrene |
black soybeans glycine max l merrill were germinated under fungal stress with food grade r oligosporus for days and were homogenized and fermented with lactic acid bacteria lab to produce soy yogurt fungal AS led to the generation of oxylipins oxooctadecadienoic acids kodes isomers and their respective glyceryl esters ... | 33|130|176|178 | stress|lactic acid|oligosaccharides|enriched |
the higher patency rates of cardiovascular implants including vascular bypass grafts stents and heart valves are related to their ability to inhibit thrombosis intimal hyperplasia and calcification in native tissue the endothelium plays a L1 role in inhibiting these processes various bioengineering research strategies ... | 34|61|87|111 | major|graft|vascular|endothelial |
we present the first enantioselective organocatalytic RPA for the synthesis of alphamethylenedeltalactones and deltalactams our methodology utilizes the michael addition of unmodified aldehydes to ethyl diethoxyphosphorylacrylate as the key step affording highly enantiomerically enriched adducts which can be transforme... | 6|59|63 | approach|general|active |
during binocular rivalry one stimulus is visible dominant while the other CS- is invisible suppressed after a few seconds perception reverses to determine whether these alternations involve competition between the eyes or between the images we measured suppression depth to monocular probes we did so in conventional riv... | 11 | stimulus |
to recover surface reflectance and illuminance from the raw luminance signal the visual system must use prior assumptions and strategies that make use of additional sources of information indeed it has been found that depending on experimental conditions lightness apparent reflectance may refer to judgments that are si... | 99 | experimental |
recent findings demonstrate that the perception of other peoples eye gaze direction can be dramatically biased by previous adaptation to that gaze direction here we further investigated this aftereffect by examining its development over time with particular attention to the potential role of the ambiguity of the TS fol... | 47|89|99 | test stimulus|minutes|function |
microsaccades are one component of the small eye movements that constitute fixation their implementation in the oculomotor system is unknown to better understand the physiological and mechanistic processes underlying microsaccade generation we studied microsaccadic inhibition a transient drop of microsaccade rate in re... | 85|191 | after|behavior |
after PE to moving stimuli illusory motion is perceived in stimuli that do not contain consistent motion a phenomenon termed the motion aftereffect mae in this T0 we tested maes under binocular suppression that renders the motion adaptor invisible for the entire adaptation period we developed a variant of the continuou... | 1|26|75 | prolonged exposure|study|functional |
we measured the justnoticeable difference jnd in orientation variance between two textures figure as we varied the baseline pedestal variance present in both textures jnds first fell as pedestal variance increased and then rose producing a dipper function similar to those previously reported for contrast blur and orien... | 51 | function |
this T0 investigated the link between drivers gaze positioning and steering SMB when negotiating bends this was conducted by directing the drivers point of gaze toward a target situated in the vicinity of the tangent point tp a region known to attract a significant amount of ocular fixations and thought to provide some... | 1|11|78|99|108 | study|behavior|behavior|behavior|fixation point |
we investigate the relationship between illusory figure detection and discrimination of its shape asking whether these depend on a single two separate or two sequential processes in a simultaneous detectiondiscrimination experiment we presented subjects with brief backwardmasked kanizsatype patterns consisting of four ... | 195|222 | detection|detection |
the objective of this study was to investigate the OD of visually driven postural regulation in typically developing children of different ages thirtytwo typically developing participants from age CG years years years years or years were asked to stand within a virtual tunnel that oscillated in an anteriorposterior fas... | 9|28 | development|groups |
a variety of mechanisms have been proposed to explain illusory contour formation however since prior studies have focused on a single mechanism there is no clear consensus regarding contour formation mechanisms here we developed a novel vivid dynamic display we call the chomping pacman that allows measurement of minute... | 94 | general |
ambiguous stimuli can look different in different contexts here we demonstrate that subjective appearance of motion depends not only on current visual input but critically on which aspects of the context are attended observers fixated a central oblique test grating flanked by two pairs of orthogonally oriented context ... | 61|125|158 | stimulus|test stimulus|physical |
binocular disparity is the input to stereopsis which is a very strong depth cue in humans however the CSD of binocular disparities in NK environments has not been quantitatively measured in this T0 we converted distances from accurate range maps of forest scenes and indoor scenes into the disparities that an observer w... | 18|23|32 | distribution|natural|study |
conflicting results have been reported about the earliest true erp differences related to face processing with the bulk of the literature focusing on the signal in the first ms after stimulus onset part of the discrepancy might be explained by uncontrolled lowlevel differences between images used to assess the timing o... | 95|161 | stimulus|onset |
we demonstrate that as an object moves color and motion signals from successive widely spaced locations are integrated but letter and digit shapes are not the features that integrate as an object moves match those that integrate when the eyes move but the object is stationary spatiotopic integration we suggest that thi... | 56|149|187|230|236|292 | large|identification|stimulus|identification|alternating|large |
the BB encounters input varying with many different time courses given such temporal R2 it would seem practical for adaptation to operate at multiple timescales indeed to account for peculiar effects such as spacing savings and spontaneous recovery many recent models of learning and adaptation have postulated multiple ... | 1|13|85 | brain|variability|cortex |
patterned backgrounds can induce large shifts in color appearance even with patterns of only scone contrast s k shevell p monnier the present study tested whether a background DP could induce color shifts even at a belowthreshold contrast in the first experiment scone contrast threshold for discriminating a DP from a h... | 28|48|115|162 | pattern|pattern|pattern|background |
we propose an efficient methodology for comparing computational models of a perceptually discriminable quantity rather than comparing MM responses to subjective responses on a set of preselected stimuli the stimuli are computersynthesized so as to optimally distinguish the models specifically given two computational mo... | 17|117 | model|stimulus |
recent results show that humans can respond with a saccadic eye movement toward faces much faster and with less error than toward other objects what feature information does your visual SC need to distinguish between different objects so rapidly in a first step we replicated the fast saccadic bias toward faces we simul... | 30 | cortex |
s kitayama s duffy t kawamura and j t larsen found that east asians when shown a line inside a square memorized more accurately the ratio of the lines length relative to the square than the lines absolute length whereas north americans showed the opposite results because of this studys important implications on cultura... | 87|101 | culture|reference |
the human face is an important and complex communication channel humans can however easily read in a face not only identity information but also facial expressions with high accuracy here we present the results of four psychophysical experiments in which we systematically manipulated certain facial areas in video seque... | 92 | correlation |
perceptual studies suggest that processing facial identity emphasizes upperface information whereas processing expressions of anger or happiness emphasizes the lowerface the two goals of the present T0 were to determine a if the distributions of eye fixations reflect these upperlowerface biases and b whether this bias ... | 26 | study |
three signals are used to visually localize targets and stimulate saccades retinal location signals for intended saccade amplitude sensorymotor transform smt of retinal signals to extraocular muscle innervation and estimates of eye position from extraretinal signals we investigated effects of adapting saccade amplitude... | 46|101 | change|after |
multifocal visual evoked potentials mfvep were recorded simultaneously for both the target and the neighbor stimuli each varying over C2 of contrast and for most conditions the relationship between the amplitude of target response and the contrast of the neighbor stimulus as well as the amplitude of the response to the... | 19|52|88|131 | levels|stimulus|model|model |
we elucidate two properties of the intrinsic constraint ic model of depth cue combination f domini c caudek h tassinari first we show that ic combines depth cues in a weighted sum that maximizes the signaltonoise ratio of the combined estimate second we show that ic predicts that any two depthmatched pairs of stimuli a... | 121 | stimulus |
this study examined the role of spatiotemporal feature attribution in the perception of the visual size of objects a small or a large leading disk a test disk of variable size and a probe disk of a fixed size were sequentially presented at the same position for durations of ms with interstimulus intervals of ms observe... | 104 | apparent motion |
physiological and psychophysical studies have demonstrated the importance of colinearity in visual processing motivated by these empirical findings we present a novel computational MM of recurrent longrange processing in the primary visual cortex unlike other models we restrict the longrange interaction to cells of par... | 23|72|73|137|145 | model|activities|after|element|classical |
sensory information travels to visual and motor areas via several distinct pathways some of them being fastlike the achromatic MC and retinotectal routesand others slowerthose carrying chromatic signals in particular sopponent signals it is debated whether common visual processing stages are used for different types of... | 19 | magnocellular |
vernier alignment thresholds are strongly compromised when the vernier is embedded in an array of equallength flanking lines here we show that these contextual interactions can be diminished by giving the flanks the opposite contrast polarity eg WG flanks surrounding a black vernier similar results are obtained for red... | 37 | white |
information in the cortex is thought to be represented by the joint activity of SN here we describe how fundamental questions about neural representation can be cast in terms of the topological structure of population activity a new method based on the concept of persistent homology is introduced and applied to the T0 ... | 14|52|59|72|75|82|108 | neurons|study|cortex|cortex|active|natural|spatial frequency |
numerous studies indicate that perceiving global object motion results from the integration of local component motions across space and time less attention has been paid to the issue of motion selection necessary to avoid spurious associations of component motions belonging to different objects and to solve the socalle... | 237 | binding |
the primate visual system faces a difficult problem whenever it encounters the motion of an object moving over a patch of the retina objects typically contain a number of edges at different orientations and so a range of image velocities are generated within the receptive field of a neuron processing the object movemen... | 83|122|157 | substrate|pattern|model |
in sensory neurophysiology reverse correlation analyses have advanced our understanding of the spatiotemporal structure of receptive fields rfs and the tuning properties of individual neurons here we used a psychophysical variant of the motion reverse correlation technique to investigate how visual selective attention ... | 46|68 | tuning curves|sequence |
image gradientssmooth changes in color and luminancemay be caused by intrinsic surface reflectance properties or extrinsic illumination phenomena including shading shadowing and interreflections in turn image gradients may provide the visual system with information concerning the origin of these factors such as the ori... | 165|219 | reference|recovery |
the standard psychophysical MM of our early visual system consists of a linear filter stage followed by a nonlinearity and an internal noise source if a rectification mechanism is introduced at the SO of the linear filter stage as has been suggested on some occasions this model actually predicts that human performance ... | 3|32|65|103|140 | model|output|levels|identical|detection |
in a visual search experiment the subject must find a target item hidden in a display of other items and their performance is measured by their reaction time rt here i look at how visual search reaction times are correlated with past reaction times targetabsent rts ie rts to displays that have no target are strongly co... | 97|101|148|157 | pattern|power spectra|after|active |
crowding effect is the visibility reduction of a target when presented with neighboring distractors it has been explained by either lateral inhibition at a preattentive level or coarse spatial resolution of attention to test these theories highresolution fmri was used to measure v response to the target in the presence... | 145 | stimulus |
objects in a scene are often partially occluded without causing the viewer any problem the occluded parts are apparently represented via amodal completion to evaluate human ability to perceive and remember partially occluded pictures we showed sequences of pictures using rapid serial visual presentation rsvp for durati... | 87|105|155|196 | detection|detection|detection|factors |
discontinuities in feature maps serve as important cues for the location of object boundaries here we used multiinput nonlinear analysis methods and eeg source imaging to assess the role of several different boundary cues in visual scene segmentation synthetic figureground displays portraying a circular figure region w... | 59 | background |
the responses of SN in the V1 v are generally inhibited by stimuli surrounding their classical receptive fields crf this surround suppression can influence the visual perception of stimuli for instance the presence of a surround stimulus can decrease the apparent contrast of a central stimulus a recent neurophysiologic... | 3|6|49 | neurons|primary visual cortex|study |
stereoscopic depth processing for static objects depends on retinal disparities between the two eyes and has been shown in previous functional imaging fmri work to involve widely distributed activity in the human visual SC including both dorsal and VP streams stereoscopic depth processing of moving objects on the other... | 33|38|98|134|143|163|232 | cortex|ventral|twodimensional|large|intraparietal sulcus|stimulus|study |
we used groundplane motion stimuli displayed on a computer monitor positioned below eye level to induce involuntary versionvergence nystagmus vvn the vvn was recorded with a search coil system it was shown that the vvn had both vertical versional and horizontal vergence components the vvn induced by backward motion tow... | 141|145|156 | peak velocity|peak velocity|model |
BMs are recognized with speed and precision even from strongly IC stimuli while cortical structures involved in biological motion recognition have been identified the nature of the underlying perceptual representation remains largely unknown we show that visual representations of complex BMs are characterized by percep... | 0|10|40|51|73|138|144 | body movements|impoverished|body movements|multidimensional scaling|stimulus|delayed matchtosample|stimulus |
whenever two or more sensory inputs are highly consistent in one or more dimensions observers will be more likely to perceive them as a single multisensory event rather than as separate unimodal events for audiovisual speech but not for other noncommunicative events participants exhibit a unity effect whereby they are ... | 51|90|130 | sensitive|specific|audiovisual |
magnetic resonance DWI coupled with fiber tractography dft is the only noninvasive method for measuring VWM pathways in the living human BB dft is often used to discover new pathways but there are also many applications particularly in visual neuroscience in which we are confident that two brain regions are connected a... | 2|15|21 | diffusionweighted imaging|white matter|brain |
previous work suggests there are mechanisms at intermediate levels of visual processing specialized for the PCD of radial and circular form the evidence in favor of specialized global form mechanisms is derived from structure PCD experiments that have told us very little about their bandwidth or number to address these... | 15|34|111 | detection|detection|variable |
intraventricular anatomy has been detailed as it pertains to endoscopic surgery within the third IVT particularly for performing ETV etv and endoscopic colloid cyst resection the expanding role of endoscopic surgery warrants a careful appraisal of these techniques as they relate to frequent anatomical variants given th... | 14|18|50 | ventricle|endoscopic third ventriculostomy|cavum septum pellucidum |
the combination of unilateral trigeminal and vagal nerve dysfunction is a rare presentation in patients with CM type i cmi the authors present a case of incomplete lateral medullary syndrome in a patient with cmi the patients symptoms of decreased unilateral facial sensitivity to pain and temperature and her vocal cord... | 16|53|54 | chiari malformation|after|posterior fossa |
cephaloceles represent primary axial mesodermal defects occurring in per live births prior studies have reported posterior location hydrocephalus microcephaly seizure and presence of brain tissue as poor prognostic markers for neurological outcome however these studies were small and the results were analyzed using uni... | 49 | study |
central nervous system maldevelopment can have different presentations in twins we report on a case of different presentations of spina bifida occulta in MZ the first twin presented at birth with a lipomyelomeningocele a tethered cord was diagnosed in the second twin at years of age neural tube defects ntds are a group... | 23 | monozygotic twins |
olfactory schwannomas are rare tumors of the anterior skull base that are possibly derived from ectopic SCs perivascular neural tissue or sensory SN of the meninges the authors report the case of a yearold boy with an olfactory schwannoma that D2 inferiorly through the cranial base and superiorly into the frontal lobe ... | 16|22|40|81|98|110|147|158 | schwann cells|nerves|extended|brain|tumor|epithelial membrane antigen|tumor|brain tumors |
meningiomas are rare in children chordoid meningioma is a very rare variant as only cases in children have been reported the authors report the first case of a chordoid meningioma in the third ventricle a yearold boy presented with HA abnormal behaviors and ataxia brain mr imaging revealed a cm wellenhanced mass in the... | 39|55|57|90|164 | headache|ventricle|hydrocephalus|caudate|tumor |
lymphangioma localized to the bones of the skull base is rare the authors report herein the case of a yearold boy who presented with lymphangioma of the bone localized to the skull base and leading to cerebrospinal fluid csf rhinorrhea with meningitis neuroimaging demonstrated lytic destruction with a cyst in the RA mi... | 51|64 | right|tumor |
postoperative progressive spinal deformity often complicates PET outcome after resection of pediatric intramedullary spinal cord PT imscts the authors propose a preoperative grading scale that correlates with the postoperative development of progressive spinal deformity requiring subsequent F0 | 6|15|36 | functional|tumors|fusion |
ventriculoperitoneal shunts vpss are commonly placed into the peritoneal cavity via a small laparotomy or blindly by using a split trocar larger patients require larger incisions and placement is made more difficult by previous abdominal operations and obesity for GA surgeons laparoscopy has become the firstchoice appr... | 39 | general |
in this singlecenter T0 the authors examined the clinical characteristics risk factors treatment strategies and outcomes in patients with thrombosis associated with ventriculoatrial va shunts | 3 | study |
to evaluate the feasibility and efficacy of salvage endoscopic extraperitoneal radical prostatectomy eerpe in recurrent prostate cancer after failed high intensity FUS therapy hifu external beam radiotherapy ebt and brachytherapy | 21 | focused ultrasound |
the merits of laparoscopic sealing devices have been poorly characterized the purpose of this T0 was to compare two bipolar sealing devices ligasure v ls and gyrus pk gp an ultrasonic device harmonic scalpel ace hs and a novel device using nanotechnology enseal ptc es | 14 | study |
previous attempts to correlate preoperative patient characteristics with operative complexity and operative time prior to laparoscopic donor nephrectomy have found few consistent relationships the purpose of this study is to determine the effect of ABD and perirenal fat measured with preoperative computerized tomograph... | 34|51 | abdominal|handassisted laparoscopic |
review of experience with endoscopic extraperitoneal radical prostatectomy eerpe for localized prostate CA | 12 | cancer |
the human and mouse genomes contain and connexin genes respectively during the last year period genetic research on connexins has been stimulated by two parallel approaches first the characterization of genetic diseases that are caused by connexin mutations and second the generation and characterization of connexin kno... | 160 | function |
direct IC via gap junctions is critical in the control and coordination of vascular CF in the CVS gap junctions are made up of one or more of four connexin proteins cx cx cx and cx the expression of more than one gapjunction protein in the vasculature is not redundant rather V1 connexins work in concert first during th... | 1|14|17|51|73|78|106|183 | intercellular communication|function|cardiovascular system|vascular|function|function|endothelial|function |
the eye lens is constantly subjected to oxidative AS from radiation and other sources the lens has several mechanisms to protect its components from oxidative AS and to maintain its redox state including enzymatic pathways and high concentrations of ascorbate and reduced glutathione with aging accumulation of Ox lens c... | 8|25|47 | stress|stress|oxidized |
the T0 for monitoring antimicrobial resistance trends smart is examining aerobic and facultatively anaerobic gramnegative bacilli gnb isolated from IA infections this report summarizes the annual data | 1|19 | study|intraabdominal |
amiloridesensitive epithelial sodium channels enac play an important role in lung sodium transport sodium transport is closely regulated to maintain an AGA fluid SL on the alveolar surface both alveolar type i and ii cells have several different sodiumpermeable channels in their apical membranes that play a role in nor... | 21|23 | appropriate|layer |
the objective of this T0 was to determine the effects of temporal hydrostatic pressure hp on the properties of scaffoldless bovine articular cartilage constructs the study was organized in three phases first a suitable control for hp application was identified second mpa static hp was applied at three different timepoi... | 4|60|196|201 | study|development|study|longterm |
the increasing demand for bone grafts combined with their limited availability and potential risks has led to much new research in bone TE current strategies of bone tissue engineering commonly use cellseeded scaffolds and flow perfusion bioreactors to stimulate the cells to produce bone tissue suitable for implantatio... | 22|129|267 | tissue engineering|stress|release |
in vitro mechanical stimulation has been reported to induce cell alignment and increase cellular proliferation and collagen synthesis our group has previously reported that in vitro mechanical stimulation of tissueengineered tendon constructs significantly increases construct stiffness and repair biomechanics after sur... | 108|176 | repetition|strain |
V1 TE represents a promising approach for the development of living smalldiameter V1 grafts that can be used for replacement therapy the culture of strong human tissueengineered te V1 grafts has required long SC times up to several months whether or not combined with GT this article describes the culture of strong gene... | 0|1|12|28|33|44|61|68|72|99|121|177 | vascular|tissue engineering|vascular|vascular|culture|gene therapy|vascular|polyglycolic acid|polyhydroxybutyrate|strain|internal mammary|fibrin |
under temperaturedependent sex determination tsd temperatures experienced by embryos during OD determine the sex of the offspring consequently populations of organisms with tsd have the potential to be strongly impacted by climatic warming that could bias offspring sex ratio a fundamental demographic parameter involved... | 10|60|62|91|102|120|254 | development|longterm|study|change|change|longterm|plasticity |
sulfadoxinepyrimethamine sp inhibits folate metabolism by the malaria parasite we investigated the association between folate C2 and sp failure in pregnant women data from a trial to assess the effect that folate supplementation has on sp failure in pregnant women were analyzed plasma folate levels were determined at e... | 15 | levels |
this study investigated pregnane x receptor polymorphisms in relation to unboosted atazanavir PC in cohorts of patients the polymorphism tc predicted concentrations below the minimum effective concentration ngml with odds ratios of p and p prospective studies determining potential clinical usefulness are now warranted | 12 | plasma concentrations |
the us food and drug administration has issued a warning that tipranavir may be associated with increased risk of intracranial hemorrhage we studied large cohorts to estimate the BG rate of intracranial hemorrhage and compared it with rates reported among persons who had been exposed to tipranavir | 28 | background |
ph pulmonary hypertension often complicates the disease course of patients with copd chronic obstructive pulmonary disease and is an indication of a worse prognosis in the present study we assessed whether pravastatin administration was ERP in improving ph and exercise capacity in copd patients with ph and whether the ... | 34|73|84|102|104|125|150|177 | effective|placebo|medical centre|placebo|after|artery pressure|study|exercise tolerance |
the failure of most nonionic detergents to release patches of drm detergentresistant membrane at degrees c undermines the claim that drms consist of lipid nanodomains that exist in an lo liquid ordered phase on the living cell surface in the present T0 we have shown that inclusion of cations mg k to mimic the intracell... | 41 | study |
bclb is a transcriptional regulator with an important role in tcell development and leukaemogenesis we demonstrated recently that bclb controls expression from the il interleukin promoter through direct IB to the us upstream site in the present T0 we provide evidence that bclb also participates in the activation of il ... | 28|37|104|122|137|140|189|195 | binding|study|degradation|specific|necrosis factor alpha|light|cancer|levels |
seven different forms of the enzyme comt catechol omethyltransferase were found in isolated rat HCs by twodimensional gel electrophoresis and immunoblotting five small variants scomt and two large variants lcomt the identities of these comt forms were verified by tryptic fingerprinting using malditof matrixassisted las... | 14|73|176|209|216 | hepatocytes|liver|liver|liver|sites |
treatment of nonsmallcell lung cancer is dependent on disease stage for patients with metastasis or locally advanced disease the importance of finding therapeutic schemes that may benefit this population is important this review discusses therapeutic options for first and secondline treatment in patients with advanced ... | 97|242|255 | effective|placebo|administered |
explaining the evolution of cooperative behavior is a longstanding problem for which much theory has been developed a recent paper in bmc biology tests CE elements of this theory by manipulating a simple bacterial experimental system this approach is useful for assessing the principles of social evolution but we argue ... | 24 | central |
controversy surrounds the potential clinical importance of or erbeta in breast cancer and three recent papers have sought to resolve this in the present issue of breast cancer research novelli and colleagues explored the significance of erbeta expression in breast cancer patients and they showed diverse relationships a... | 7 | oestrogen receptor |
in extensive disease of small cell lung cancer a doubling of the oneyearsurvival rate was reported in august by prophylactic cranial irradiation applied to patients who experienced any response to initial chemotherapy we discuss the treatment concept of extensive disease in the face of the latest results and older stud... | 52|71|102|138|142|154|161 | thoracic irradiation|complete|responders|local control|radiochemotherapy|prophylactic cranial irradiation|tumor |
gastric outlet obstruction usually presents with nonbilious vomiting colicky epigastric pain loss of appetite and occasionally upper gastrointestinal bleeding causes can be classified as benign or malignant or as extra or IL gastrojejunostomy is a wellrecognised surgical procedure performed to bypass gastric outlet one... | 31|43 | intraluminal|obstruction |
PWS pws is a rare multisystem genetic disease leading to severe complications mainly related to obesity we strongly lack information on the NK history of this complex disease and on what factors are involved in its evolution and its outcome one of the objectives of the french reference centre for praderwilli syndrome s... | 0|22 | praderwilli syndrome|natural |
epidemiological data indicate elevated psychosocial health risks for physicians e g burnout depression marital disturbances alcohol and substance abuse and suicide the purpose of this study was to identify psychosocial health resources and risk factors in professionrelated behaviour and experience patterns of medical s... | 53 | appropriate |
the yusho poisoning incident which was caused by RB oil contaminated with polychlorinated biphenyls pcbs polychlorinated quarterphenyls pcqs and polychlorinated dibenzofurans pcdfs generated by heat denaturation of pcb occurred in in western japan annual physical dermatological dental ophthalmological and laboratory ex... | 8|46 | rice bran|after |
segmental duplications sds are euchromatic portions of genomic dna or kb that occur at more than one site within the genome and typically share a high level of sequence identity approximately of the human genome is composed of such duplicated sequences here we report the detailed investigation of chek duplications chek... | 59 | cell cycle |
an increasing number of scientific research projects require access to largescale computational resources this is particularly true in the biological field whether to facilitate the analysis of C1 highthroughput data sets or to perform large numbers of complex simulations a characteristic of the emerging field of syste... | 27 | large |
it is often the case that rat genes are alternatively spliced the resulting alternate transcripts often encode protein isoforms that differ in CAA sequences changes among the protein isoforms can alter the cellular properties of proteins the effect can range from a subtle modulation to a complete loss of function | 6|22 | mammalian|amino acid |
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