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the response of nadph cytochrome c reductase nccr activity in CL of labeo rohita fish exposed to the pesticides microgl endosulfan and mgl MCP was studied in terms of specific enzyme activity mumg protein a significant level of nccr was observed in the liver tissues of labeo rohita exposed to the pesticides when compar... | 10|23|114 | liver|monocrotophos|liver |
synthetic pyrethroids are the recent major class of broad spectrum photostable organic insecticides used in agricultural domestic and veterinary applications and now account for more than of global insecticide use cypermethrin is metabolized and eliminated significantly more slowly by fish than by mammals or birds whic... | 103|127|131 | exposure|general|exposure |
ceratophyllum demersum homwort was subjected to toxic concentrations of al and mg l zn and mg l and cu and mg l in SC solutions for days the higher dose of al enhanced the chlorophyll content significantly p in the first days of treatment while other treatments caused marked reductions NRA nra was significantly reduced... | 23|50|130 | culture|nitrate reductase activity|factors |
during and hr of exposure the digestive PG of lymnaea treated with a lethal concentration of mgl cuso revealed intense activity of acid phosphatase in perilobular margin on the other hand same area of the gland showed moderate activity of atpase during and hr of SE however ALP phosphatase showed average activity in per... | 7|45|47|63 | glands|exposure|alkaline|exposure |
lake uluabat known for its scenic beauty and richness of aquatic life is situated in marmara region bursa turkey on account of its importance lake uluabat was designated by the ministry of environment as a ramsar site in physical chemical and microbiological parameters of the aquatic ecosystem in lake uluabat were meas... | 93|178 | dissolved oxygen|study |
dichlorophenoxyacetic acid d is a post emergence herbicide the tests were conducted to study the toxicity of d using ec value in four dilutions d was applied at concentration of and mg l in the potato dextrose agar medium the effect of this herbicide was evaluated as the colony forming unit cfu ec value for dilution of... | 77|85 | untreated|administered |
investigation on physicochemical parameters and bacteial characteristics of the coral reef environs of the gulf of mannar biosphere reserve was studied the study found the influence of different physicochemical parameters on one another and also on the distribution of the total heterotrophic bacteria thb in the coral r... | 64 | areas |
a T0 concerning the effects of elevation and exposure of the spruce forests on defoliation C2 of oriental spruce picea orientalis l link by ips typographus l was carried out during and in artvinhatila national park turkey nine spruce stands were selected at zones of elevations m m and m and at different aspects to asse... | 1|15|61|96|125|158 | study|levels|exposure|study|northern|levels |
the present investigation deals with fluoride removal from aqueous solution by thermally G1 neem azadirachta indica leaves carbon anc and thermally activated kikar acacia arabica leaves carbon akc adsorbents in this study neem leaves carbon and kikar leaves carbon prepared by heating the leaves at degrees c in electric... | 12|126|134|176|183|231 | activated|activated|activated|line|ambient temperature|natural |
in this paper shannonweaver si sii siii siv and sv diversity index was applied to surface phytoplankton to T0 the water quality status of river bhadra receiving mysore paper mill and iron and steel mill effluent a total of species of phytoplankton belonging to classes were recorded and study indicated that the phytopla... | 18|73 | study|quality |
the present study was to evaluate heavy metal toxicity stress PS in fish blood during longterm exposure of sublethal concentration of copper sulphate cuso the effects of copper on various heamatological parameters were evaluated exposing indian fresh water fish channa punctatus to a sublethal concentration of copper su... | 10|127|186 | symptoms|exposure|after |
the pesticides are one of the most potentially harmful chemicals liberated in the environment in an unplanned manner malathion is widely used as a potent pesticide in many countries and has been shown to produce some adverse health effects a study was conducted to asses the effects of malathion on the male reproductive... | 65|160|177 | dose levels|alkaline|study |
the effluent from a lucknow based distillery mohan meakin distillery was analyzed for physicochemical and biological parameters of pollution and concentration of potentially toxic heavy metals cd cr ni and zn and the effect of the distillery effluent as such and on dilution with tap water was studied on seed germinatio... | 106|204 | chemical oxygen demand|symptoms |
this T0 describes the histological alterations of the internal organs of prince joseph habsburg and his first wife alexandra pavlovna romanova both corpses were mummified and the internal organs were stored separately in rosemary oil in metal vessels royal prince joseph habsburg died on january the microscopic study co... | 1|120|138 | study|newborn|nodes |
whereas AIP is an established entity characterized by high SS concentrations of igg igg cholangitis is a quite new entity characterized by a massive infiltration of bile ducts by igg positive lymphoplasmocytic cells igg cholangitis should therefore be differentiated from primary SC based on clinics radiological and bio... | 1|9|41 | autoimmune pancreatitis|serum|sclerosing cholangitis |
in the course of a chronic infection with the hepatitis c virus the fibrosis progression rate varies among individuals and depends on the existence of certain cofactors in this context a growing interest has emerged and has focused on insulin resistance in fact the SH c virus is now recognized as being responsible for ... | 44|99 | hepatitis|chronic hepatitis c |
diarrhea is a frequent adverse event involving the most frequently antibiotics laxatives and nsai drug induced diarrhea may be acute or chronic it may be due to expected dose dependant properties of the drug to immunoallergic or biogenomic mechanisms several pathophysiological mechanisms have been described resulting i... | 48|74 | secretory|ischemic |
gastroesophageal reflux disease is a common condition that requires no additional exam if the diagnosis is straightforward and no complications is suspected ph monitoring is often used for atypical PS or if there is no response to therapy with proton pump inhibitors this was considered for decades as a gold standard bu... | 29|84|92 | symptoms|symptoms|symptoms |
in the first peroral appendectomy was carried out in a human subject in order to prevent the premature adoption in clinical practice of the socalled natural orifice transluminal endoscopic surgery notes a rational framework for its development was proposed in T3 animal experimentation further ABD interventions were car... | 40|44|61 | after|abdominal|approach |
to study the early postoperative tau and safety of combined viscocanalostomy with trabeculectomy viscotrab for treating faradvanced glaucoma | 5 | efficacy |
a survey was undertaken to ascertain current practices in ophthalmic RA with an emphasis on subtenons block despite its increasing use there are currently no guidelines for its explicit management | 10 | regional anesthesia |
this study evaluates the effectiveness of akten akorn inc buffalo grove il a novel ophthalmic gel anesthetic agent for CR ocular anesthesia | 19 | complete |
a yearold woman had convergent strabismus fixus associated with high myopia bilateral medial rectus recession and loop myopexy of lateral and MR muscles was performed the clinical characteristics and the possible surgical treatment modalities were discussed this surgery seems ERP on both the restoration of dislocation ... | 21|39 | medial rectus|effective |
a patient with a painful blind eye underwent enucleation and bioceramic orbital implantation the bioceramic implant was wrapped with polyglactin mesh and anteriorly capped with a scleral patch graft because there was tension on the wound a relaxing conjunctival incision on the fornix was performed implant exposure with... | 54|67|69|94 | after|graft|graft|after |
the purpose of this article was to report the misposition and subsequent retrieval of an express optonol ltd neve ilan israel glaucoma drainage device implanted in an eye with pseudoexfoliative glaucoma the formation of excessive fibrosis at the site of the implant which was partly dislocated into the anterior chamber ... | 81 | trabeculectomy |
a yearold man was treated with one session of endoscopic cyclophotocoagulation for uncontrolled elevated intraocular pressure before treatment the eye was quiet and uninflamed pretreatment visual acuity was and the intraocular pressure was mm hg treatment was applied to the ciliary processes for nearly degrees during t... | 68|82|106 | visual acuity|visual acuity|cyclophotocoagulation |
a patient with uncontrolled primary openangle glaucoma underwent SLT and developed a significant AC reaction shallow AC and choroidal effusion common complications associated with selective LTP include conjunctival injection mild anterior chamber reaction and posttreatment intraocular pressure elevation the authors bel... | 8|13|16|25 | selective laser trabeculoplasty|anterior chamber|anterior chamber|laser trabeculoplasty |
a yearold woman presented to the emergency room hours after a jellyfish sting to the left eye centrally located linear epithelial defects were observed on slitlamp evaluation the epithelial defects improved but did not heal totally after meticulous patching with antibiotic ointment and cycloplegic drops small subepithe... | 79|90|118 | areas|visual acuity|bodies |
a yearold man with T3 glaucoma status post trabeculectomy and pseudophakia had a symptomatic recurrent band and bullous keratopathy in his left eye three previous ethylenediaminetetraacetic acid chelations with immediate recurrence of the calcic band keratopathy with frequent breakdown produced recurrent painful cornea... | 4 | advanced |
an yearold man underwent penetrating keratoplasty for pseudophakic bullous keratopathy in the left eye postoperatively a thin transparent membrane in the anterior chamber was noted the differential diagnosis included vitreous prolapse retained capsule fibrinous anterior chamber membrane and retained descemets membrane ... | 43|54|58 | anterior chamber|descemets membrane|optical coherence tomography |
iris arteriovenous malformation also labeled as iris racemose hemangioma is a rare condition in which abnormal vessels are present on the iris surface slitlamp findings in addition to anterior segment fluorescein angiographic features of such lesions have been described in the past the authors report anterior segment O... | 47 | optical coherence tomography |
a scleral fixation technique for posterior dislocated intraocular lens performed through gauge vitrectomy cannulas is presented it is based on the creation of PP loops at opposite meridians through which haptics are engaged and placed in the sulcus repositioning of the intraocular lens as opposed to substitution that r... | 23|92 | polypropylene|after |
juvenile idiopathic arthritis is the most common chronic autoimmune disease the outcome of this inflammatory disease is uncertain patients may suffer from severe joint damage leading to mutilations as well as from extraarticular manifestations the prognosis is VL and depends in part on the number of affected joints and... | 37|67|76|128 | variable|combination therapy|classical|placebo |
the need for measures of the quality of healthcare provided to children and adolescents is well documented however children have been underrepresented in national healthcare SQ measurement and reporting efforts the pediatric data quality systems pediqs collaborative is addressing this gap two consensus measure sets and... | 25|65 | quality|development |
teamwork and good communication are central to the provision of highquality care a standardized focusgroup protocol was used analysis assessed emergent themes of patient safetyrelated effective and problematic clinician communication sixtythree focus CG were conducted with clinicians from five chicago pediatric patient... | 32 | groups |
when children are dying in a hospital setting healthcare providers need to help families make important endoflife care decisions most providers use the term do not resuscitate dnr when suggesting a course of action that involves not using extraordinary lifesaving measures some healthcare providers use the term allow na... | 57 | study |
infection of the prosthetic aortic graft bypass remains one of the most serious complications of aortoiliac bypass grafts use of an aortoiliac allograft as a replacement for an infected prosthetic VG is an effective treatment for this problem however the availability of aortoiliac grafts is affected by the high rate of... | 30|52|82 | graft|errors|abdominal |
to compare university of wisconsin solution viaspan the universal standard for organ preservation with HTK an analysis of each solution in REF to PCTs with specific organs is presented and assessed to find the tau of each in a clinical environment also to view each solution from an economical standpoint and in the end ... | 14|21|23|34 | histidinetryptophanketoglutarate solution|reference|clinical trials|efficacy |
information about the relationship between family disagreement and donation decisions may facilitate OD of strategies to help families resolve conflict and possibly increase donation consent rates | 12 | development |
the Tx kidney lying heterotopically in the iliac fossa is especially vulnerable to damage from blunt trauma particularly compression by vehicle seatbelt we present a case wherein a functioning renal allograft lying in the right iliac fossa was severely injured by seatbelt compression resulting in significant PET compro... | 1|46 | transplanted|functional |
the need for deceased donor organs for kidney transplantation in the united states continues to increase the increasing demand has fueled desperate attempts by patients to circumvent the long waiting list of the united network for organ sharing we report patients with endstage kidney disease who sought and obtained a l... | 108|114 | transplant|transplant |
organ transplantation is a complex and highly regulated field this review focuses on the role of nurses and transplant coordinators in solid organ transplantation excluding both inpatient staff nursing and procurement activities the literature describes a robust and autonomous transplant coordinator role a key member o... | 48|90|110 | transplant|transplant|levels |
the expected number of unacceptable patient results due to an undetected malfunctionenucan be set as a patientbased quality goal using the number of patients tested between qc specimens as a design parameter allows one to design qc strategies that meet specified patientbased SQ goals the qc utilization rate can be mini... | 42 | quality |
thoracic surgeons participating in this survey seemed to have clearly indicated their perception of vats major lung resections in particular vats lobectomy the acronym vats as a short form of videoassisted thoracic surgery was the preferred terminology according to the respondents the need or use of rib spreading serve... | 171|297 | posterolateral thoracotomy|development |
vats lobectomy is an acceptable alternative to open lobectomy for treating earlystage nsclc although no large randomized control trial has compared these procedures recent C1 series and casecontrol studies provide strong evidence that patients undergoing vats lobectomy have less pain fewer perioperative complications s... | 24 | large |
thoracoscopic lobectomy is emerging as the procedure of choice for patients with early stage nonsmall cell LC based on advantages in quality of life as well as longterm outcomes in addition thoracoscopic lobectomy has been demonstrated to be safe and effective for selected patients with locally advanced disease and for... | 16|68 | lung cancer|complete |
vats lobectomy as defined by calgb provides the same oncologic surgery as that performed through a thoracotomy standardizing the terminology is the first step that must be undertaken to standardize the T0 vats lobectomy is the use of technology to aid in performing an established procedure this technology and OD of the... | 31|49 | operation|development |
this article describes minimally invasive open surgery for resection of intrapulmonary HM this RPA compensates for the weak points of videoassisted thoracic surgery while remaining minimally invasive overall it is respected as a technically feasible alternative to conventional lobectomy by way of open thoracotomy with ... | 11|13 | malignancies|approach |
surgery remains the mainstay for the treatment of lung cancer while pulmonary resection has been safe for years there is a trend toward minimally invasive vats pulmonary resections studies have now shown that standard complete CA operations performed via vats offer patients a shorter hospital stay and quicker recovery ... | 35 | cancer |
the past two decades have witnessed a revolutionary transition in surgical technique and technology with the OD of minimally invasive approaches many advantages were obtained by using VATS less surgical trauma and pain shorter hospital stay and satisfactory cosmetic results limitations still remain however because of i... | 16|27 | development|videoassisted thoracoscopic surgery |
fasttracking protocols or postoperative care computerized algorithms have been shown to reduce hospital los and reduce costs for patients who undergo both open and vats procedures the ability to fasttrack is not governed by the type of procedure closed versus open but rather by patient characteristics and the mindset o... | 184 | physical |
the effort to reduce the invasiveness of thoracic surgery is increasing in this specialty in this context preliminary evidence has shown that uniportal VATS represents a valuable option to perform different diagnostic and curative procedures this article addresses the topic of uniportal videoassisted thoracic surgery a... | 23|50|60 | videoassisted thoracic surgery|approach|intrathoracic |
the authors initial experience with awake videothoracoscopic lung resection suggests that these procedures can be easily and safely performed under sole TEA with no mortality and negligible morbidity one major concern was that operating on a ventilating lung would render surgical maneuvers more difficult because of the... | 21|92|162|165|206|209|356|476|501 | thoracic epidural anesthesia|general anesthesia|control patients|epidural anesthesia|development|panic attacks|peripheral|active|pneumothorax |
in summary from the different alternatives to conventional hospitalization developed in the last decades outpatient surgery has been the one with the greatest growth however only few studies have been reported on thoracic surgery and there is still great potential for an increase in OP thoracic surgery the aim of this ... | 44|75 | outpatient|bilateral |
longterm hematopoietic cell transplantation hct survivors have a high prevalence of severe and chronic health conditions placing significant demands on the healthcare system the objective of the current T0 was to evaluate and compare the healthcare utilization by adult hispanic and nonhispanic white LTS of hct | 28|43 | study|longterm survivors |
this paper details the responses made by social scientists as well as criminal justice practitioners during to a study focusing on the status of criminology by the bureau of social hygiene these responses ultimately led to the publication of the controversial crime law and social science which gave muchneeded direction... | 52 | development |
isolation of adequate numbers of fetal cells circulating in the maternal circulation is the L1 hurdle in developing noninvasive prenatal diagnostic procedures we used flow cytometry and a combination of different monoclonal antibodies to compare the yield and purity of the fetal nucleated red blood cells at different p... | 14 | major |
prebiotics are nondigestible fermentable SF that are reported to have health benefits for the host older as well as more recent studies show beneficial effects in experimental colitis and lately also in human inflammatory bowel diseases ibd such as crohns disease ulcerative colitis and chronic pouchitis in this review ... | 4|96|140|194|197 | fibers|proinflammatory|function|large|clinical trials |
it has been speculated that prenatal or perinatal exposure to infections affects the risk for developing inflammatory bowel disease ibd the aims of the study were to investigate the seasonal and monthly variations of birth dates among patients with CD cd and ulcerative colitis uc | 39 | crohns disease |
overactivity of glutamatergic neurotransmission in the basal ganglia is known to be closely related to the onset and pathogenesis of parkinsons disease glu homeostasis around glutamatergic synapses is tightly regulated by two groups of glutamate transporters glial glu transporters glt eaat and glast eaat and neuronal g... | 22|37|56|57|59|61|66|157|205|206 | glutamate|glutamate|glutamate transporters|after|onset|parkinsons disease|animal model|glutamate|glutamate transporters|after |
neuroactive substances such as serotonin and other monoamines have been suggested to be involved in the transmission of gustatory signals from taste bud cells to afferent fibers lampreys are the earliest vertebrates that possess taste buds although these differ in structure from taste buds in jawed vertebrates and thei... | 67|139|207 | glutamate|large|fibers |
implantation serine protease isp was first identified in the uteri of Pr mice it is thought that isp may have an important role in the initiation of implantation however the expression status and detailed functions of isp remain unclear in this study the expression of isp was investigated in the rat uterus the analysis... | 11|201 | pregnant|gene expression |
the objective of this study was to evaluate the efficacy safety and tolerability of istradefylline mg once daily versus placebo as an adjunct to levodopa in subjects with parkinsons disease pd who have motor fluctuations istradefylline kw is an adenosine aa receptor antagonist that in primate models of pd improves moto... | 51|89|95|182 | function|stable|stable|levodopa |
we describe the presenting features and longterm outcomes of patients with electrophysiologicallyconfirmed psychogenic tremor clinical information for all patients with psychogenic tremor confirmed by our MD neurophysiology laboratory was reviewed a followup questionnaire was administered to all included patients in ps... | 25|118|133|167 | movement disorders|after|symptoms|after |
this study was designed to specifically characterize the autonomic phenotype of cardiorespiratory dysregulation during the nighttime in young girls with mecp mutationconfirmed rett syndrome rs studied in their home environment computerized breathtobreath and beattobeat characterization of athome continuously recorded R... | 39|111|155|157 | respiratory inductance plethysmography|respiratory inductance plethysmography|breathing|heart |
the rate limiting step in dna biosynthesis is the reduction of ribonucleotides to form the corresponding deoxyribonucleotides this reaction is catalyzed by ribonucleotide reductases rnrs and is an attractive target against rapidly proliferating pathogens class i rnrs are binuclear nonheme iron enzymes and can be furthe... | 178|189|224 | tyrosine|binding|development |
enzymes of the rnf family are believed to be bacterial redoxdriven ion pumps coupling an oxidoreduction process to the translocation of na across the CM here we show for the first time that rnf is a flavoprotein with fmn covalently bound to threonine in rnfg and a second flavin bound to threonine in rnfd rnf subunits d... | 24|197|248 | cell membrane|binding|semiquinone |
exp and computational studies have indicated that hydrophobicity plays a key role in driving the insertion of transmembrane alphahelices into lipid bilayers MD allow exploration of the nature of the interactions of TM alphahelices with their lipid bilayer environment in particular coarsegrained simulations have conside... | 0|22|32|90|188|196|229 | experimental|molecular dynamics simulations|transmembrane|model|insertion|model|energy |
to establish a direct method for monitoring ATP binding in cytochrome peryf applicable at elevated hydrostatic pressures we introduce a laser dye fluorolga fga as a novel fluorescent ligand the high intensity of fluorescence and the reasonable resolution of the excitation band from the absorbance bands of p allowed us ... | 7|53|78|89|125|132|174 | substrate|sensitive|resonance energy transfer|binding|displacement|lowspin|binding |
lipid binding of human apolipoprotein ai apoai occurs initially through the cterminal alphahelices followed by conformational reorganization of the NT helix bundle this led us to hypothesize that apoai has multiple lipidbound conformations in which the nterminal helix bundle adopts either open or closed conformations a... | 19|48|92|186|218 | nterminal|cterminal domain|pyrene|isothermal titration calorimetry|nterminal |
a new approach the immunospin trapping CA used a novel rabbit polyclonal antidmpo dimethylpyrroline noxide AS to detect protein radicalderived dmpo nitrone adducts in the hemoprotein mycobacterium tuberculosis catalaseperoxidase katg this work demonstrates that the formation of protein nitrone adducts is dependent on t... | 6|15|52|55|92|101|123 | assay|antiserum|western blotting|enzymelinked immunosorbent|amino acid|tyrosine|isoniazid |
phosphoinositide kinase gamma pikgamma is activated by gbetagamma PR after stimulation of galpha i coupled receptors involving a recruitment of the enzyme to the plasma membrane via interaction of the regulatory subunit p or p with gbetagamma the receptormediated release of gbetagamma was however insufficient to elicit... | 8|53|94|175|178|187|189 | release|classical|after|approach|plasma membrane|after|release |
the electronic structure and chemical bonding in the ta cluster are investigated using photoelectron spectroscopy and density functional theory calculations photoelectron spectra are obtained for ta at four photon energies and nm while congested spectra are observed at high electron IB energies several lowlying electro... | 40|66 | binding|density functional calculations |
cyanoacetaldehyde ncch cho which may have played a role in the prebiotic formation of the pyrimidine bases cytosine and uracil is formed in water solutions by addition of water to cyanoacetylene hcccn a compound that exists in interstellar space in comets and planetary atmospheres a gasphase model of the uncatalyzed ad... | 132 | energy |
the multiple cf bond character of phcfme ions has been examined by means of theory vibrational spectroscopy of the gaseous ions and unimolecular decomposition chemistry atoms in molecules analysis of dft wave functions gives a cf bond order of n as compared with n for me cf relative to n for fluoromethane and n for dia... | 94|181 | agreement|transition state |
the photophysics of the pyrene radical cation a polycyclic Ah pah and a possible source of diffuse interstellar bands dibs is investigated by means of hybrid molecular mechanicsvalence bond mmvb force field and multiconfigurational casscf and caspt ab initio methods potential SE surfaces of the first three electronic s... | 9|41 | aromatic hydrocarbon|energy |
our study is aimed at understanding the characteristics of PET group descriptors based on peaks of the electronic density distribution rhor the descriptors calculated are the rhor value at peak location volume ellipticity curvatures of rho r and the peakfunctional group distance by the implementation of an automated an... | 9|97|98|130 | functional|functional|groups|functional |
bidentate inhibitors of protein tyrosine phosphatase b ptpb are considered as a group of ideal inhibitors with high IB potential and high selectivity in treating type ii diabetes in this paper the binding models of five bidentate inhibitors to ptpb tcptp and shp were investigated and compared by using molecular dynamic... | 18|67|93|129|139|169 | binding|surface area|surface area|active|binding|binding |
the free energy surfaces and reaction mechanisms underlying the activation of amino acids by cos in bulk water at ambient conditions as well as extreme temperaturepressure thermodynamic conditions were studied using accelerated ab initio molecular dynamics the results for the reaction sequence leading from glycine to i... | 47|132|156 | activated|isocyanate|aqueous |
understanding the PSA functions of proteins is an important factor in elucidating their cellular and physiological functions due to the predominance of biopolymer interactions in biology many methods have been designed to interrogate and identify biologically relevant interactions that proteins make to dna rna and othe... | 2|52|86 | biochemical|binding|natural |
in an effort to probe the role of the znii sites in MBL l mononuclear metal ion containing and heterobimetallic analogues of the enzyme were generated and characterized using kinetic and spectroscopic studies MNC zniicontaining l which binds znii in the consensus zn site was shown to be slightly active however this enz... | 12|33|152 | metallobetalactamase|mononuclear|resting state |
reproducible detection of a target molecule is demonstrated using temporally SD solutionphase silicavoidgold nanoparticles and surfaceenhanced raman scattering sers these composite nanostructures are homogeneous diameter nm and entrap single nm gold nanoparticle cores inside porous Si membranes which prevent electromag... | 10|35|82|89 | stable|silica|silica|stable |
the glycerophosphodiesterase gpdq from enterobacter aerogenes is a promiscuous binuclear metallohydrolase that catalyzes the hydrolysis of mono di and triester substrates including some organophosphate pesticides and products of the Kd of nerve agents gpdq has attracted recent attention as a promising enzymatic bioreme... | 29|212 | degradation|regulatory |
disubstituted benzobisoxazoles have been synthesized by a highly efficient reaction of diaminobenzene diols with various orthoesters the scope of this new reaction for the synthesis of substituted benzobisoxazoles has been investigated using four different orthoesters the utility of these EDC as building blocks for the... | 39 | compounds |
a novel tandem aziridinationrearrangement reaction of allylic alcohols has been discovered in which the significant accelerating effect of Si gel has been identified on the basis of this methodology an efficient and highly stereoselective approach to various quaternary mannich bases has been put in place readily provid... | 18 | silica |
the ID of commercial shark species is a relevant issue to ensure the correct labeling of seafood products to maintain consumer confidence in seafood and to enhance the knowledge of the species and volumes that are at present being captured thus improving the management of shark fisheries the polymerase chain reaction w... | 1|113 | identification|identification |
during vdj recombination site TPS dna excision is dictated by the binding of rag proteins to the conserved recombination signal CS rss within the genome the interaction between rag and rss is thought to involve a large dna distortion that is permissive for dna cleavage in this study using atomic force microscopy imagin... | 4|20|82|133|156 | specific|sequence|specific|change|intact |
a method for sampling and electrophoretic analysis of aqueous plugs segmented in a stream of immiscible oil is described in the method an aqueous buffer and oil stream flow parallel to each other to form a stable virtual wall in a microfabricated kshaped fluidic element as aqueous sample plugs in the oil stream make co... | 80|152 | electrophoresis|aqueous |
PA pa is a reactive low molecular weight compound used in the chemical industry the exposure of pa may lead to workrelated airway diseases such as rhinitis chronic bronchitis and asthma the SE gives rise to an increase in haptenspecific igg antibodies in workers but with a low presence of specific ige antibodies in thi... | 0|32|61|67|167 | phthalic anhydride|exposure|human hemoglobin|trypsin|binding |
interactions of oppositely charged macroions in aqueous solution give rise to intriguing aggregation phenomena resulting in finitesize longlived clusters characterized by a quite narrow size distribution particularly the adsorption of highly charged linear polyelectrolytes on oppositely charged colloidal particles is s... | 53|157|205 | polymer|central|polyacrylate |
the rapid advancement of nanotechnology has created a vast array of engineered nanomaterials enms which have unique PCS size shape crystallinity surface charge and chemical surface coating elemental composition and solubility attributes these physicochemical properties of enms can produce chemical conditions to induce ... | 17|101|119|155|219|232|237|293 | physical|alveolar|exposure|exposure|tumor necrosis|culture|exposure|stress |
four new cembranoids querciformolides ad along with two known cembranoids and have been isolated from the soft coral sinularia querciformis furthermore chemical investigation of sinularia granosa has afforded three new cembranoids querciformolide b and granosolides a and b the structures of the new metabolites were elu... | 84|121 | tetrahydrofuran|cancer |
many of todays drug discovery programs use highthroughput screening methods that rely on quick evaluations of protein activity to rank potential chemical leads by monitoring biologically relevant proteinligand interactions nmr can provide a means to validate these discovery leads and to optimize the drug discovery proc... | 51|85|86|127|140|185 | change|complete|binding|binding|binding|agreement |
we recently reported that the ferrocenecontaining cationic lipid bfdma bisferrocenylundecyldimethylammonium bromide can be used to mediate cell transfection and that levels of transfection depend critically upon the oxidation state of the ferrocenyl CG of the lipid here we report that the redox activity of bfdma can be... | 32|109|220|226 | groups|oxidized|study|approach |
redmond red a fluoropore containing a redoxactive phenoxazine core has been explored as a new electrochemical probe for the detection of abasic sites in doublestranded dna the electrochemical SMB of redmond redmodified dna at gold surfaces exhibits SD quasireversible voltammetry with a midpoint potential centered aroun... | 28|37 | behavior|stable |
we report the design and synthesis of an orthogonally protected peptide nucleic acid pna building block fmocpnauddeoh and its use in the construction of pna fret probes this building block allows for the postsynthetic attachment of reporter CG to the amino group attached to the position of uracil u following selective ... | 37 | groups |
a series of analogues of tetrahydrolipstatin thl were synthesized and tested as inhibitors of the formation or hydrolysis of the endocannabinoid 2-AG ag three of the novel compounds ie and inhibited ag formation via the diacylglycerol lipase alpha daglalpha with ic values lower than nm ic of thl microm and were between... | 21|75|76 | arachidonoylglycerol|fatty acid|amide |
a new type of superalkalisuperhalogen compound blix x f lif bef bf is theoretically predicted the interaction between superalkali bli and different shaped superhalogen x is found to be strong and ionic in nature bond energies of these blix species are in the range of kcalmol at the ccsdtaugccpvdz level which are much l... | 59 | energy |
the speciation of uraniumvi in micromolar aqueous solutions at ambient atmosphere was studied by ATR fouriertransform infrared atr ftir spectroscopy and by speciation modeling applying the updated nea thermodynamic database it can be shown that reliable infrared spectra of micromolar uvi solutions are obtained abolishi... | 14|63 | attenuated total reflection|change |
an original lowtemperature solidstate route for the preparation of metal betadiketonates in their unsolvated forms has been suggested four new first row divalent transition metal betadiketonates mhfac m mn fe co and ni hfac hexaluoroacetylacetonate have been isolated in quantitative yield compounds have been obtained b... | 63|101 | nickel|lewis |
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