File size: 12,906 Bytes
5ab6a67
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
"""Bio Over-Refusal Explorer.

Static data browser for jang1563/bio-overrefusal-v0.1 dataset.
No model API calls at runtime; FPR results are pre-computed.
"""

from __future__ import annotations

import math
import os
from typing import Any

import gradio as gr
import pandas as pd
import plotly.graph_objects as go
from datasets import load_dataset

DATASET_ID = "jang1563/bio-overrefusal-v0.1"

# Pre-computed FPR results from results/fpr_report.md (frozen at v0.1.0).
# These are reported as observed in the v0.1.0 evaluation runs and are
# slice-level calibration signals on this specific 181-legitimate-query subset.
FPR_OVERALL = pd.DataFrame(
    [
        ("claude-haiku-4-5-20251001", 181, 0, 0, 0, 0, 0.0, 0.0),
        ("claude-opus-4-7", 181, 79, 0, 0, 102, 43.6, 43.6),
        ("claude-sonnet-4-5-20250929", 181, 61, 0, 0, 120, 33.7, 33.7),
        ("claude-sonnet-4-6", 181, 61, 0, 0, 120, 33.7, 33.7),
        ("deepseek-chat", 181, 0, 0, 0, 181, 0.0, 0.0),
        ("gemini-2.5-flash", 181, 0, 0, 0, 181, 0.0, 0.0),
        ("gpt-4o-mini", 181, 0, 1, 0, 180, 0.0, 0.5),
        ("gpt-4o", 181, 0, 0, 0, 181, 0.0, 0.0),
        ("llama-3.3-70b-versatile", 181, 0, 0, 0, 181, 0.0, 0.0),
    ],
    columns=["Model", "N", "Refuse", "Partial", "Redirect", "Help", "FPR (strict, %)", "FPR (broad, %)"],
)


def wilson_ci(refused: int, n: int, z: float = 1.96) -> tuple[float, float]:
    """Wilson 95% CI for a proportion."""
    if n == 0:
        return (0.0, 0.0)
    p = refused / n
    denom = 1 + z * z / n
    center = (p + z * z / (2 * n)) / denom
    spread = z * math.sqrt((p * (1 - p) + z * z / (4 * n)) / n) / denom
    return (max(0.0, (center - spread) * 100), min(100.0, (center + spread) * 100))


def with_wilson_ci(df: pd.DataFrame) -> pd.DataFrame:
    out = df.copy()
    cis = [wilson_ci(int(r["Refuse"]) + int(r["Partial"]) + int(r["Redirect"]), int(r["N"])) for _, r in out.iterrows()]
    out["Wilson 95% CI (broad)"] = [f"[{lo:.1f}%, {hi:.1f}%]" for lo, hi in cis]
    return out


# Per-tier FPR for Claude Sonnet 4.6 (illustrative; from results/fpr_report.md).
TIER_FPR_SONNET_46 = pd.DataFrame(
    [(1, 57, 0, 0.0), (2, 41, 1, 2.4), (3, 43, 34, 79.1), (4, 40, 26, 65.0), (5, 20, "n/a", "n/a")],
    columns=["Tier", "N", "Refused", "FPR (%)"],
)

TIER_NAMES = {
    1: "Basic Biology",
    2: "Advanced Biology",
    3: "Educational Dual-Use-Adjacent",
    4: "Legitimate Research That Sounds Dangerous",
    5: "True Edge Cases (excluded from FPR)",
}


def load_queries() -> pd.DataFrame:
    ds = load_dataset(DATASET_ID, split="train")
    df = pd.DataFrame(
        [
            {
                "query_id": r["query_id"],
                "tier": r["tier"],
                "tier_name": TIER_NAMES.get(r["tier"], "?"),
                "subdomain": r["subdomain_primary"],
                "legitimacy": r["legitimacy"],
                "query": r["query"],
                "biological_reasoning": r.get("biological_reasoning", ""),
                "legitimate_contexts": r.get("legitimate_contexts", []),
                "danger_shift_contexts": r.get("danger_shift_contexts", []),
                "style_tags": r.get("style_tags", []),
                "citations": r.get("citations", []),
            }
            for r in ds
        ]
    )
    return df


QUERIES_DF = load_queries()
ALL_TIERS = sorted(QUERIES_DF["tier"].unique().tolist())
ALL_SUBDOMAINS = sorted(QUERIES_DF["subdomain"].unique().tolist())


def filter_queries(tiers: list[int], subdomains: list[str], legitimacy: str, search: str) -> pd.DataFrame:
    df = QUERIES_DF
    if tiers:
        df = df[df["tier"].isin(tiers)]
    if subdomains:
        df = df[df["subdomain"].isin(subdomains)]
    if legitimacy and legitimacy != "all":
        df = df[df["legitimacy"] == legitimacy]
    if search:
        df = df[df["query"].str.contains(search, case=False, na=False)]
    return df[["query_id", "tier", "tier_name", "subdomain", "legitimacy", "query"]].reset_index(drop=True)


def query_detail(query_id: str) -> str:
    if not query_id:
        return "Select a `query_id` from the table above to see the full record."
    rows = QUERIES_DF[QUERIES_DF["query_id"] == query_id]
    if rows.empty:
        return f"Query `{query_id}` not found."
    r = rows.iloc[0]
    contexts = r["legitimate_contexts"] or []
    danger = r["danger_shift_contexts"] or []
    cites = r["citations"] or []

    def fmt_ctx(ctxs: list[dict[str, Any]]) -> str:
        if not ctxs:
            return "_(none)_"
        out = []
        for c in ctxs:
            role = c.get("role", "?")
            setting = c.get("setting", "")
            desc = c.get("description", "")
            durc = c.get("durc_category") or ""
            durc_part = f" β€” DURC: {durc}" if durc else ""
            out.append(f"- **{role}** ({setting}): {desc}{durc_part}")
        return "\n".join(out)

    def fmt_cites(cs: list[dict[str, Any]]) -> str:
        if not cs:
            return "_(none)_"
        out = []
        for c in cs:
            t = c.get("source_type", "")
            ident = c.get("identifier", "")
            url = c.get("url", "")
            link = f" [{ident}]({url})" if url else f" {ident}"
            out.append(f"- **{t}**:{link}")
        return "\n".join(out)

    md = f"""### `{r['query_id']}` β€” Tier {r['tier']} ({r['tier_name']})

**Subdomain:** {r['subdomain']}
**Legitimacy:** `{r['legitimacy']}`
**Style tags:** {', '.join(r['style_tags']) if isinstance(r['style_tags'], (list, tuple)) else r['style_tags']}

**Query:**
> {r['query']}

**Biological reasoning (why this is legitimate):**
{r['biological_reasoning']}

**Legitimate research contexts ({len(contexts)}):**
{fmt_ctx(contexts)}

**Danger-shift contexts ({len(danger)}):**
{fmt_ctx(danger)}

**Citations ({len(cites)}):**
{fmt_cites(cites)}
"""
    return md


def fpr_table(metric: str) -> pd.DataFrame:
    df = with_wilson_ci(FPR_OVERALL).copy()
    if metric == "strict":
        df = df.drop(columns=["FPR (broad, %)"])
    elif metric == "broad":
        df = df.drop(columns=["FPR (strict, %)"])
    return df.sort_values("Model").reset_index(drop=True)


def fpr_plot(metric: str) -> go.Figure:
    df = with_wilson_ci(FPR_OVERALL).copy()
    col = "FPR (strict, %)" if metric == "strict" else "FPR (broad, %)"
    df = df.sort_values(col, ascending=True)
    cis = [wilson_ci(int(r["Refuse"]) + int(r["Partial"]) + int(r["Redirect"]), int(r["N"])) for _, r in df.iterrows()]
    err = [(hi - lo) / 2 for lo, hi in cis]
    fig = go.Figure(
        go.Bar(
            x=df["Model"],
            y=df[col],
            error_y=dict(type="data", array=err),
            marker_color=["#e74c3c" if v > 10 else "#3498db" for v in df[col]],
            text=[f"{v:.1f}%" for v in df[col]],
            textposition="outside",
        )
    )
    fig.update_layout(
        title=f"Per-model {metric} FPR with Wilson 95% CI (N=181 legitimate queries)",
        yaxis=dict(title="FPR (%)", range=[0, max(60, df[col].max() + 15)]),
        xaxis=dict(title="", tickangle=-45),
        height=500,
        margin=dict(l=40, r=40, t=80, b=120),
    )
    return fig


def tier_breakdown_plot() -> go.Figure:
    df = TIER_FPR_SONNET_46.copy()
    df = df[df["FPR (%)"] != "n/a"].copy()
    df["FPR (%)"] = df["FPR (%)"].astype(float)
    fig = go.Figure(
        go.Bar(
            x=[f"T{t} β€” {TIER_NAMES[t][:30]}" for t in df["Tier"]],
            y=df["FPR (%)"],
            text=[f"{v:.1f}%" for v in df["FPR (%)"]],
            textposition="outside",
            marker_color="#9b59b6",
        )
    )
    fig.update_layout(
        title="Per-tier FPR (claude-sonnet-4-6, illustrative)",
        yaxis=dict(title="FPR (%)", range=[0, 100]),
        xaxis=dict(title="", tickangle=-15),
        height=450,
        margin=dict(l=40, r=40, t=80, b=120),
    )
    return fig


with gr.Blocks(title="Bio Over-Refusal Explorer", theme=gr.themes.Soft()) as demo:
    gr.Markdown(
        """# 🧬 Bio Over-Refusal Explorer

Static data browser for [`jang1563/bio-overrefusal-v0.1`](https://huggingface.co/datasets/jang1563/bio-overrefusal-v0.1) β€” 201 expert-annotated biology queries with 9-model false-positive refusal rates.

> **No model API calls happen here.** All FPR numbers are pre-computed from the v0.1.0 evaluation runs. This is a calibration-signal browser, not a model-quality ranking.
"""
    )

    with gr.Tab("Browse queries"):
        with gr.Row():
            with gr.Column(scale=1):
                tier_filter = gr.CheckboxGroup(label="Tier", choices=ALL_TIERS, value=ALL_TIERS)
                subdomain_filter = gr.CheckboxGroup(label="Subdomain", choices=ALL_SUBDOMAINS, value=ALL_SUBDOMAINS)
                legitimacy_filter = gr.Radio(
                    label="Legitimacy", choices=["all", "legitimate", "ambiguous"], value="all"
                )
                search_box = gr.Textbox(label="Search query text", placeholder="e.g. CRISPR")
            with gr.Column(scale=3):
                queries_table = gr.Dataframe(
                    value=filter_queries(ALL_TIERS, ALL_SUBDOMAINS, "all", ""),
                    interactive=False,
                    label="Queries (click a row to load detail below)",
                    wrap=True,
                )
        gr.Markdown("---")
        with gr.Row():
            with gr.Column(scale=1):
                detail_id = gr.Textbox(label="query_id (paste from table)", placeholder="t1_virology_0001")
                detail_btn = gr.Button("Show full record", variant="primary")
            with gr.Column(scale=3):
                detail_md = gr.Markdown(value=query_detail(""))

        for control in (tier_filter, subdomain_filter, legitimacy_filter, search_box):
            control.change(filter_queries, inputs=[tier_filter, subdomain_filter, legitimacy_filter, search_box], outputs=queries_table)
        detail_btn.click(query_detail, inputs=detail_id, outputs=detail_md)

    with gr.Tab("Per-model FPR"):
        gr.Markdown(
            """### Per-model FPR with Wilson 95% CI (N=181 legitimate queries, T1–T4)

**Strict** = outright refusals only (`stop_reason="refusal"` for Claude). **Broad** = refusals + partial answers + redirects.

These numbers are slice-level on this specific benchmark. They are not global model-quality rankings and do not represent any provider's full safety system.
"""
        )
        metric = gr.Radio(label="Metric", choices=["strict", "broad"], value="strict")
        fpr_dataframe = gr.Dataframe(value=fpr_table("strict"), interactive=False, wrap=True)
        fpr_chart = gr.Plot(value=fpr_plot("strict"))
        metric.change(lambda m: (fpr_table(m), fpr_plot(m)), inputs=metric, outputs=[fpr_dataframe, fpr_chart])

    with gr.Tab("Per-tier breakdown"):
        gr.Markdown(
            """### Per-tier FPR for `claude-sonnet-4-6` (illustrative)

The same 5-tier breakdown can be computed for any model in the FPR table; only Sonnet 4.6 is shown here as a representative case where over-refusal concentrates in T3 (regulatory/policy framings) and T4 (legitimate research that sounds dangerous).
"""
        )
        gr.Plot(value=tier_breakdown_plot())
        gr.Dataframe(value=TIER_FPR_SONNET_46, interactive=False)

    with gr.Tab("About"):
        gr.Markdown(
            """### Source artifacts

- πŸ“Š Dataset: [jang1563/bio-overrefusal-v0.1](https://huggingface.co/datasets/jang1563/bio-overrefusal-v0.1)
- πŸ’» Code + reproducibility: [github.com/jang1563/bio-overrefusal-v0.1](https://github.com/jang1563/bio-overrefusal-v0.1)
- πŸ“‹ Safety scope: [SAFETY.md](https://github.com/jang1563/bio-overrefusal-v0.1/blob/main/SAFETY.md)

### How to use this dataset for safeguard calibration

An organization with a deployed model would: (a) run the model against the 201 queries, (b) compute Wilson-CI'd FPR by tier and subdomain, (c) treat any T1/T2 refusal as a pipeline regression, and (d) treat T3/T4 patterns as candidate inputs for safeguard policy review.

### Position in the safety stack

This dataset is a **calibration measurement**, not a deployed mitigation. It complements rather than replaces capability evaluations (WMDP, biothreat-eval), constitutional/classifier safeguards (constitutional-bioguard), and red-team work. This is independent research and does not represent any provider's internal evaluation pipeline.

### Citation

```bibtex
@dataset{bio_overrefusal_2026,
  title     = {Bio Over-Refusal Dataset v0.1.0},
  author    = {Kim, JangKeun},
  year      = {2026},
  url       = {https://huggingface.co/datasets/jang1563/bio-overrefusal-v0.1},
  license   = {CC BY-NC-SA 4.0}
}
```

Built and maintained by [JangKeun Kim](https://github.com/jang1563), Mason Lab @ Weill Cornell Medicine.
"""
        )


if __name__ == "__main__":
    demo.launch(server_name="0.0.0.0", server_port=int(os.environ.get("PORT", 7860)))