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Initial: bio over-refusal v0.1.0 static data explorer

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  1. README.md +34 -7
  2. app.py +327 -0
  3. requirements.txt +4 -0
README.md CHANGED
@@ -1,13 +1,40 @@
1
  ---
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- title: Bio Overrefusal Explorer
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- emoji: 📉
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- colorFrom: yellow
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- colorTo: indigo
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  sdk: gradio
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- sdk_version: 6.14.0
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- python_version: '3.13'
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  app_file: app.py
10
  pinned: false
 
 
 
 
 
 
 
 
11
  ---
12
 
13
- Check out the configuration reference at https://huggingface.co/docs/hub/spaces-config-reference
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
  ---
2
+ title: Bio Over-Refusal Explorer
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+ emoji: 🧬
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+ colorFrom: blue
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+ colorTo: purple
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  sdk: gradio
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+ sdk_version: 4.44.0
 
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  app_file: app.py
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  pinned: false
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+ license: cc-by-nc-sa-4.0
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+ short_description: Browse 201 expert-annotated biology queries + 9-model FPR
12
+ tags:
13
+ - ai-safety
14
+ - biosafety
15
+ - llm-evaluation
16
+ - over-refusal
17
+ - calibration
18
  ---
19
 
20
+ # Bio Over-Refusal Explorer
21
+
22
+ Static data browser for the [Bio Over-Refusal Dataset v0.1.0](https://huggingface.co/datasets/jang1563/bio-overrefusal-v0.1) — 201 domain-expert-authored biology research queries stratified by sensitivity tier, with 9-model false-positive refusal rates and Wilson 95% confidence intervals.
23
+
24
+ **No model API calls happen at runtime.** This Space loads pre-computed evaluation results from the dataset and lets you browse them by tier, subdomain, and legitimacy. Provider names are reported as observed; numbers should be read as a slice-level calibration signal for this specific biology-research benchmark, not as a global model-quality ranking.
25
+
26
+ ## What you can do here
27
+
28
+ 1. **Browse queries** — Filter the 201 queries by tier (1–5), subdomain (10), and legitimacy. Click a row to see the full record (biological reasoning, legitimate contexts, citations, danger-shift contexts).
29
+ 2. **Compare models** — See the 9-model FPR table with Wilson 95% CIs. Switch between strict and broad FPR.
30
+ 3. **Per-tier breakdown** — See how each model's FPR varies across the 5 sensitivity tiers.
31
+
32
+ ## Source artifacts
33
+
34
+ - 📊 Dataset: [jang1563/bio-overrefusal-v0.1](https://huggingface.co/datasets/jang1563/bio-overrefusal-v0.1)
35
+ - 💻 Code + reproducibility: [github.com/jang1563/bio-overrefusal-v0.1](https://github.com/jang1563/bio-overrefusal-v0.1)
36
+ - 📋 Safety scope: [SAFETY.md](https://github.com/jang1563/bio-overrefusal-v0.1/blob/main/SAFETY.md)
37
+
38
+ ## Position in the safety stack
39
+
40
+ This dataset is a **calibration measurement**, not a deployed mitigation. It complements rather than replaces capability evaluations (e.g. WMDP, biothreat-eval), constitutional/classifier safeguards, and red-team work. This work is independent and does not represent any provider's internal evaluation pipeline.
app.py ADDED
@@ -0,0 +1,327 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ """Bio Over-Refusal Explorer.
2
+
3
+ Static data browser for jang1563/bio-overrefusal-v0.1 dataset.
4
+ No model API calls at runtime; FPR results are pre-computed.
5
+ """
6
+
7
+ from __future__ import annotations
8
+
9
+ import math
10
+ import os
11
+ from typing import Any
12
+
13
+ import gradio as gr
14
+ import pandas as pd
15
+ import plotly.graph_objects as go
16
+ from datasets import load_dataset
17
+
18
+ DATASET_ID = "jang1563/bio-overrefusal-v0.1"
19
+
20
+ # Pre-computed FPR results from results/fpr_report.md (frozen at v0.1.0).
21
+ # These are reported as observed in the v0.1.0 evaluation runs and are
22
+ # slice-level calibration signals on this specific 181-legitimate-query subset.
23
+ FPR_OVERALL = pd.DataFrame(
24
+ [
25
+ ("claude-haiku-4-5-20251001", 181, 0, 0, 0, 0, 0.0, 0.0),
26
+ ("claude-opus-4-7", 181, 79, 0, 0, 102, 43.6, 43.6),
27
+ ("claude-sonnet-4-5-20250929", 181, 61, 0, 0, 120, 33.7, 33.7),
28
+ ("claude-sonnet-4-6", 181, 61, 0, 0, 120, 33.7, 33.7),
29
+ ("deepseek-chat", 181, 0, 0, 0, 181, 0.0, 0.0),
30
+ ("gemini-2.5-flash", 181, 0, 0, 0, 181, 0.0, 0.0),
31
+ ("gpt-4o-mini", 181, 0, 1, 0, 180, 0.0, 0.5),
32
+ ("gpt-4o", 181, 0, 0, 0, 181, 0.0, 0.0),
33
+ ("llama-3.3-70b-versatile", 181, 0, 0, 0, 181, 0.0, 0.0),
34
+ ],
35
+ columns=["Model", "N", "Refuse", "Partial", "Redirect", "Help", "FPR (strict, %)", "FPR (broad, %)"],
36
+ )
37
+
38
+
39
+ def wilson_ci(refused: int, n: int, z: float = 1.96) -> tuple[float, float]:
40
+ """Wilson 95% CI for a proportion."""
41
+ if n == 0:
42
+ return (0.0, 0.0)
43
+ p = refused / n
44
+ denom = 1 + z * z / n
45
+ center = (p + z * z / (2 * n)) / denom
46
+ spread = z * math.sqrt((p * (1 - p) + z * z / (4 * n)) / n) / denom
47
+ return (max(0.0, (center - spread) * 100), min(100.0, (center + spread) * 100))
48
+
49
+
50
+ def with_wilson_ci(df: pd.DataFrame) -> pd.DataFrame:
51
+ out = df.copy()
52
+ cis = [wilson_ci(int(r["Refuse"]) + int(r["Partial"]) + int(r["Redirect"]), int(r["N"])) for _, r in out.iterrows()]
53
+ out["Wilson 95% CI (broad)"] = [f"[{lo:.1f}%, {hi:.1f}%]" for lo, hi in cis]
54
+ return out
55
+
56
+
57
+ # Per-tier FPR for Claude Sonnet 4.6 (illustrative; from results/fpr_report.md).
58
+ TIER_FPR_SONNET_46 = pd.DataFrame(
59
+ [(1, 57, 0, 0.0), (2, 41, 1, 2.4), (3, 43, 34, 79.1), (4, 40, 26, 65.0), (5, 20, "n/a", "n/a")],
60
+ columns=["Tier", "N", "Refused", "FPR (%)"],
61
+ )
62
+
63
+ TIER_NAMES = {
64
+ 1: "Basic Biology",
65
+ 2: "Advanced Biology",
66
+ 3: "Educational Dual-Use-Adjacent",
67
+ 4: "Legitimate Research That Sounds Dangerous",
68
+ 5: "True Edge Cases (excluded from FPR)",
69
+ }
70
+
71
+
72
+ def load_queries() -> pd.DataFrame:
73
+ ds = load_dataset(DATASET_ID, split="train")
74
+ df = pd.DataFrame(
75
+ [
76
+ {
77
+ "query_id": r["query_id"],
78
+ "tier": r["tier"],
79
+ "tier_name": TIER_NAMES.get(r["tier"], "?"),
80
+ "subdomain": r["subdomain_primary"],
81
+ "legitimacy": r["legitimacy"],
82
+ "query": r["query"],
83
+ "biological_reasoning": r.get("biological_reasoning", ""),
84
+ "legitimate_contexts": r.get("legitimate_contexts", []),
85
+ "danger_shift_contexts": r.get("danger_shift_contexts", []),
86
+ "style_tags": r.get("style_tags", []),
87
+ "citations": r.get("citations", []),
88
+ }
89
+ for r in ds
90
+ ]
91
+ )
92
+ return df
93
+
94
+
95
+ QUERIES_DF = load_queries()
96
+ ALL_TIERS = sorted(QUERIES_DF["tier"].unique().tolist())
97
+ ALL_SUBDOMAINS = sorted(QUERIES_DF["subdomain"].unique().tolist())
98
+
99
+
100
+ def filter_queries(tiers: list[int], subdomains: list[str], legitimacy: str, search: str) -> pd.DataFrame:
101
+ df = QUERIES_DF
102
+ if tiers:
103
+ df = df[df["tier"].isin(tiers)]
104
+ if subdomains:
105
+ df = df[df["subdomain"].isin(subdomains)]
106
+ if legitimacy and legitimacy != "all":
107
+ df = df[df["legitimacy"] == legitimacy]
108
+ if search:
109
+ df = df[df["query"].str.contains(search, case=False, na=False)]
110
+ return df[["query_id", "tier", "tier_name", "subdomain", "legitimacy", "query"]].reset_index(drop=True)
111
+
112
+
113
+ def query_detail(query_id: str) -> str:
114
+ if not query_id:
115
+ return "Select a `query_id` from the table above to see the full record."
116
+ rows = QUERIES_DF[QUERIES_DF["query_id"] == query_id]
117
+ if rows.empty:
118
+ return f"Query `{query_id}` not found."
119
+ r = rows.iloc[0]
120
+ contexts = r["legitimate_contexts"] or []
121
+ danger = r["danger_shift_contexts"] or []
122
+ cites = r["citations"] or []
123
+
124
+ def fmt_ctx(ctxs: list[dict[str, Any]]) -> str:
125
+ if not ctxs:
126
+ return "_(none)_"
127
+ out = []
128
+ for c in ctxs:
129
+ role = c.get("role", "?")
130
+ setting = c.get("setting", "")
131
+ desc = c.get("description", "")
132
+ durc = c.get("durc_category") or ""
133
+ durc_part = f" — DURC: {durc}" if durc else ""
134
+ out.append(f"- **{role}** ({setting}): {desc}{durc_part}")
135
+ return "\n".join(out)
136
+
137
+ def fmt_cites(cs: list[dict[str, Any]]) -> str:
138
+ if not cs:
139
+ return "_(none)_"
140
+ out = []
141
+ for c in cs:
142
+ t = c.get("source_type", "")
143
+ ident = c.get("identifier", "")
144
+ url = c.get("url", "")
145
+ link = f" [{ident}]({url})" if url else f" {ident}"
146
+ out.append(f"- **{t}**:{link}")
147
+ return "\n".join(out)
148
+
149
+ md = f"""### `{r['query_id']}` — Tier {r['tier']} ({r['tier_name']})
150
+
151
+ **Subdomain:** {r['subdomain']}
152
+ **Legitimacy:** `{r['legitimacy']}`
153
+ **Style tags:** {', '.join(r['style_tags']) if isinstance(r['style_tags'], (list, tuple)) else r['style_tags']}
154
+
155
+ **Query:**
156
+ > {r['query']}
157
+
158
+ **Biological reasoning (why this is legitimate):**
159
+ {r['biological_reasoning']}
160
+
161
+ **Legitimate research contexts ({len(contexts)}):**
162
+ {fmt_ctx(contexts)}
163
+
164
+ **Danger-shift contexts ({len(danger)}):**
165
+ {fmt_ctx(danger)}
166
+
167
+ **Citations ({len(cites)}):**
168
+ {fmt_cites(cites)}
169
+ """
170
+ return md
171
+
172
+
173
+ def fpr_table(metric: str) -> pd.DataFrame:
174
+ df = with_wilson_ci(FPR_OVERALL).copy()
175
+ if metric == "strict":
176
+ df = df.drop(columns=["FPR (broad, %)"])
177
+ elif metric == "broad":
178
+ df = df.drop(columns=["FPR (strict, %)"])
179
+ return df.sort_values("Model").reset_index(drop=True)
180
+
181
+
182
+ def fpr_plot(metric: str) -> go.Figure:
183
+ df = with_wilson_ci(FPR_OVERALL).copy()
184
+ col = "FPR (strict, %)" if metric == "strict" else "FPR (broad, %)"
185
+ df = df.sort_values(col, ascending=True)
186
+ cis = [wilson_ci(int(r["Refuse"]) + int(r["Partial"]) + int(r["Redirect"]), int(r["N"])) for _, r in df.iterrows()]
187
+ err = [(hi - lo) / 2 for lo, hi in cis]
188
+ fig = go.Figure(
189
+ go.Bar(
190
+ x=df["Model"],
191
+ y=df[col],
192
+ error_y=dict(type="data", array=err),
193
+ marker_color=["#e74c3c" if v > 10 else "#3498db" for v in df[col]],
194
+ text=[f"{v:.1f}%" for v in df[col]],
195
+ textposition="outside",
196
+ )
197
+ )
198
+ fig.update_layout(
199
+ title=f"Per-model {metric} FPR with Wilson 95% CI (N=181 legitimate queries)",
200
+ yaxis=dict(title="FPR (%)", range=[0, max(60, df[col].max() + 15)]),
201
+ xaxis=dict(title="", tickangle=-45),
202
+ height=500,
203
+ margin=dict(l=40, r=40, t=80, b=120),
204
+ )
205
+ return fig
206
+
207
+
208
+ def tier_breakdown_plot() -> go.Figure:
209
+ df = TIER_FPR_SONNET_46.copy()
210
+ df = df[df["FPR (%)"] != "n/a"].copy()
211
+ df["FPR (%)"] = df["FPR (%)"].astype(float)
212
+ fig = go.Figure(
213
+ go.Bar(
214
+ x=[f"T{t} — {TIER_NAMES[t][:30]}" for t in df["Tier"]],
215
+ y=df["FPR (%)"],
216
+ text=[f"{v:.1f}%" for v in df["FPR (%)"]],
217
+ textposition="outside",
218
+ marker_color="#9b59b6",
219
+ )
220
+ )
221
+ fig.update_layout(
222
+ title="Per-tier FPR (claude-sonnet-4-6, illustrative)",
223
+ yaxis=dict(title="FPR (%)", range=[0, 100]),
224
+ xaxis=dict(title="", tickangle=-15),
225
+ height=450,
226
+ margin=dict(l=40, r=40, t=80, b=120),
227
+ )
228
+ return fig
229
+
230
+
231
+ with gr.Blocks(title="Bio Over-Refusal Explorer", theme=gr.themes.Soft()) as demo:
232
+ gr.Markdown(
233
+ """# 🧬 Bio Over-Refusal Explorer
234
+
235
+ Static data browser for [`jang1563/bio-overrefusal-v0.1`](https://huggingface.co/datasets/jang1563/bio-overrefusal-v0.1) — 201 expert-annotated biology queries with 9-model false-positive refusal rates.
236
+
237
+ > **No model API calls happen here.** All FPR numbers are pre-computed from the v0.1.0 evaluation runs. This is a calibration-signal browser, not a model-quality ranking.
238
+ """
239
+ )
240
+
241
+ with gr.Tab("Browse queries"):
242
+ with gr.Row():
243
+ with gr.Column(scale=1):
244
+ tier_filter = gr.CheckboxGroup(label="Tier", choices=ALL_TIERS, value=ALL_TIERS)
245
+ subdomain_filter = gr.CheckboxGroup(label="Subdomain", choices=ALL_SUBDOMAINS, value=ALL_SUBDOMAINS)
246
+ legitimacy_filter = gr.Radio(
247
+ label="Legitimacy", choices=["all", "legitimate", "ambiguous"], value="all"
248
+ )
249
+ search_box = gr.Textbox(label="Search query text", placeholder="e.g. CRISPR")
250
+ with gr.Column(scale=3):
251
+ queries_table = gr.Dataframe(
252
+ value=filter_queries(ALL_TIERS, ALL_SUBDOMAINS, "all", ""),
253
+ interactive=False,
254
+ label="Queries (click a row to load detail below)",
255
+ wrap=True,
256
+ )
257
+ gr.Markdown("---")
258
+ with gr.Row():
259
+ with gr.Column(scale=1):
260
+ detail_id = gr.Textbox(label="query_id (paste from table)", placeholder="t1_virology_0001")
261
+ detail_btn = gr.Button("Show full record", variant="primary")
262
+ with gr.Column(scale=3):
263
+ detail_md = gr.Markdown(value=query_detail(""))
264
+
265
+ for control in (tier_filter, subdomain_filter, legitimacy_filter, search_box):
266
+ control.change(filter_queries, inputs=[tier_filter, subdomain_filter, legitimacy_filter, search_box], outputs=queries_table)
267
+ detail_btn.click(query_detail, inputs=detail_id, outputs=detail_md)
268
+
269
+ with gr.Tab("Per-model FPR"):
270
+ gr.Markdown(
271
+ """### Per-model FPR with Wilson 95% CI (N=181 legitimate queries, T1–T4)
272
+
273
+ **Strict** = outright refusals only (`stop_reason="refusal"` for Claude). **Broad** = refusals + partial answers + redirects.
274
+
275
+ These numbers are slice-level on this specific benchmark. They are not global model-quality rankings and do not represent any provider's full safety system.
276
+ """
277
+ )
278
+ metric = gr.Radio(label="Metric", choices=["strict", "broad"], value="strict")
279
+ fpr_dataframe = gr.Dataframe(value=fpr_table("strict"), interactive=False, wrap=True)
280
+ fpr_chart = gr.Plot(value=fpr_plot("strict"))
281
+ metric.change(lambda m: (fpr_table(m), fpr_plot(m)), inputs=metric, outputs=[fpr_dataframe, fpr_chart])
282
+
283
+ with gr.Tab("Per-tier breakdown"):
284
+ gr.Markdown(
285
+ """### Per-tier FPR for `claude-sonnet-4-6` (illustrative)
286
+
287
+ The same 5-tier breakdown can be computed for any model in the FPR table; only Sonnet 4.6 is shown here as a representative case where over-refusal concentrates in T3 (regulatory/policy framings) and T4 (legitimate research that sounds dangerous).
288
+ """
289
+ )
290
+ gr.Plot(value=tier_breakdown_plot())
291
+ gr.Dataframe(value=TIER_FPR_SONNET_46, interactive=False)
292
+
293
+ with gr.Tab("About"):
294
+ gr.Markdown(
295
+ """### Source artifacts
296
+
297
+ - 📊 Dataset: [jang1563/bio-overrefusal-v0.1](https://huggingface.co/datasets/jang1563/bio-overrefusal-v0.1)
298
+ - 💻 Code + reproducibility: [github.com/jang1563/bio-overrefusal-v0.1](https://github.com/jang1563/bio-overrefusal-v0.1)
299
+ - 📋 Safety scope: [SAFETY.md](https://github.com/jang1563/bio-overrefusal-v0.1/blob/main/SAFETY.md)
300
+
301
+ ### How to use this dataset for safeguard calibration
302
+
303
+ An organization with a deployed model would: (a) run the model against the 201 queries, (b) compute Wilson-CI'd FPR by tier and subdomain, (c) treat any T1/T2 refusal as a pipeline regression, and (d) treat T3/T4 patterns as candidate inputs for safeguard policy review.
304
+
305
+ ### Position in the safety stack
306
+
307
+ This dataset is a **calibration measurement**, not a deployed mitigation. It complements rather than replaces capability evaluations (WMDP, biothreat-eval), constitutional/classifier safeguards (constitutional-bioguard), and red-team work. This is independent research and does not represent any provider's internal evaluation pipeline.
308
+
309
+ ### Citation
310
+
311
+ ```bibtex
312
+ @dataset{bio_overrefusal_2026,
313
+ title = {Bio Over-Refusal Dataset v0.1.0},
314
+ author = {Kim, JangKeun},
315
+ year = {2026},
316
+ url = {https://huggingface.co/datasets/jang1563/bio-overrefusal-v0.1},
317
+ license = {CC BY-NC-SA 4.0}
318
+ }
319
+ ```
320
+
321
+ Built and maintained by [JangKeun Kim](https://github.com/jang1563), Mason Lab @ Weill Cornell Medicine.
322
+ """
323
+ )
324
+
325
+
326
+ if __name__ == "__main__":
327
+ demo.launch(server_name="0.0.0.0", server_port=int(os.environ.get("PORT", 7860)))
requirements.txt ADDED
@@ -0,0 +1,4 @@
 
 
 
 
 
1
+ gradio==4.44.0
2
+ datasets>=2.14
3
+ pandas>=2.0
4
+ plotly>=5.18