Sailor2: Sailing in South-East Asia with Inclusive Multilingual LLMs
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qnguyen3
authored a
paper 5 days ago
MaziyarPanahi
posted an update 14 days ago
Post
1139
Training mRNA Language Models Across 25 Species for $165
We built an end-to-end protein AI pipeline covering structure prediction, sequence design, and codon optimization. After comparing multiple transformer architectures for codon-level language modeling, CodonRoBERTa-large-v2 emerged as the clear winner with a perplexity of 4.10 and a Spearman CAI correlation of 0.40, significantly outperforming ModernBERT. We then scaled to 25 species, trained 4 production models in 55 GPU-hours, and built a species-conditioned system that no other open-source project offers. Complete results, architectural decisions, and runnable code below.
https://huggingface.co/blog/OpenMed/training-mrna-models-25-species
We built an end-to-end protein AI pipeline covering structure prediction, sequence design, and codon optimization. After comparing multiple transformer architectures for codon-level language modeling, CodonRoBERTa-large-v2 emerged as the clear winner with a perplexity of 4.10 and a Spearman CAI correlation of 0.40, significantly outperforming ModernBERT. We then scaled to 25 species, trained 4 production models in 55 GPU-hours, and built a species-conditioned system that no other open-source project offers. Complete results, architectural decisions, and runnable code below.
https://huggingface.co/blog/OpenMed/training-mrna-models-25-species
MaziyarPanahi
posted an update 21 days ago
Post
2213
We annotated 119K medical images with two frontier VLMs (Qwen 3.5, Kimi K2.5), cross-validated at 93% agreement, and produced 110K training records, all for under $500. Fine-tuning 3 small models (2-3B params) improved all benchmarks: best model reaches +15.0% average exact match.
Everything is open-sourced: datasets, adapters, and code.
https://huggingface.co/blog/OpenMed/synthvision
Everything is open-sourced: datasets, adapters, and code.
https://huggingface.co/blog/OpenMed/synthvision
- 2 replies
Goekdeniz-Guelmez
submitted a
paper to Daily Papers about 1 month ago
MaziyarPanahi
posted an update about 1 month ago
Post
4825
DNA, mRNA, proteins, AI. I spent the last year going deep into computational biology as an ML engineer. This is Part I of what I found. 🧬
In 2024, AlphaFold won the Nobel Prize in Chemistry.
By 2026, the open-source community had built alternatives that outperform it.
That's the story I find most interesting about protein AI right now. Not just the science (which is incredible), but the speed at which open-source caught up. Multiple teams, independently, reproduced and then exceeded AlphaFold 3's accuracy with permissive licenses. The field went from prediction to generation: we're not just modeling known proteins anymore, we're designing new ones.
I spent months mapping this landscape for ML engineers. What the architectures actually are (spoiler: transformers and diffusion models), which tools to use for what, and which ones you can actually ship commercially.
New post on the Hugging Face blog: https://huggingface.co/blog/MaziyarPanahi/protein-ai-landscape
Hope you all enjoy! 🤗
In 2024, AlphaFold won the Nobel Prize in Chemistry.
By 2026, the open-source community had built alternatives that outperform it.
That's the story I find most interesting about protein AI right now. Not just the science (which is incredible), but the speed at which open-source caught up. Multiple teams, independently, reproduced and then exceeded AlphaFold 3's accuracy with permissive licenses. The field went from prediction to generation: we're not just modeling known proteins anymore, we're designing new ones.
I spent months mapping this landscape for ML engineers. What the architectures actually are (spoiler: transformers and diffusion models), which tools to use for what, and which ones you can actually ship commercially.
New post on the Hugging Face blog: https://huggingface.co/blog/MaziyarPanahi/protein-ai-landscape
Hope you all enjoy! 🤗
- 2 replies
Goekdeniz-Guelmez
authored a
paper about 1 month ago
MaziyarPanahi
authored a
paper about 2 months ago
MaziyarPanahi
posted an update 2 months ago
Post
2371
Announcing: OpenMed Multilingual PII Detection Models
Today I am releasing 105 open-source models for Personally Identifiable Information (PII) detection in French, German, and Italian.
All Apache 2.0 licensed. Free for commercial use. No restrictions.
Performance:
- French: 97.97% F1 (top model)
- German: 97.61% F1 (top model)
- Italian: 97.28% F1 (top model)
All top-10 models per language exceed 96% F1
Coverage:
55+ PII entity types per language
Native ID formats: NSS (French), Sozialversicherungsnummer (German), Codice Fiscale (Italian)
Language-specific address, phone, and name patterns
Training Data:
French: 49,580 samples
German: 42,250 samples
Italian: 40,944 samples
Why Multilingual?
European healthcare operates in European languages. Clinical notes, patient records, and medical documents are generated in French, German, Italian, and other languages.
Effective de-identification requires:
- Native language understanding — not translation
- Local ID format recognition — each country has unique patterns
- Cultural context awareness — names, addresses, and formats vary
- These models deliver production-ready accuracy without requiring data to leave your infrastructure or language.
HIPAA & GDPR Compliance
Built for US and European privacy regulations:
- On-premise deployment: Process data locally with zero external dependencies
- Data sovereignty: No API calls, no cloud services, no cross-border transfers
- Air-gapped capable: Deploy in fully isolated environments if required
- Regulatory-grade accuracy: Supporting Expert Determination standards
- HIPAA and GDPR compliance across languages, without compliance gaps.
Use Cases
- Hospital EHR systems: Automated patient record de-identification
- Clinical research: Multilingual dataset preparation for studies
- Insurance companies: Claims processing across
https://huggingface.co/collections/OpenMed/multilingual-pii-and-de-identification
Today I am releasing 105 open-source models for Personally Identifiable Information (PII) detection in French, German, and Italian.
All Apache 2.0 licensed. Free for commercial use. No restrictions.
Performance:
- French: 97.97% F1 (top model)
- German: 97.61% F1 (top model)
- Italian: 97.28% F1 (top model)
All top-10 models per language exceed 96% F1
Coverage:
55+ PII entity types per language
Native ID formats: NSS (French), Sozialversicherungsnummer (German), Codice Fiscale (Italian)
Language-specific address, phone, and name patterns
Training Data:
French: 49,580 samples
German: 42,250 samples
Italian: 40,944 samples
Why Multilingual?
European healthcare operates in European languages. Clinical notes, patient records, and medical documents are generated in French, German, Italian, and other languages.
Effective de-identification requires:
- Native language understanding — not translation
- Local ID format recognition — each country has unique patterns
- Cultural context awareness — names, addresses, and formats vary
- These models deliver production-ready accuracy without requiring data to leave your infrastructure or language.
HIPAA & GDPR Compliance
Built for US and European privacy regulations:
- On-premise deployment: Process data locally with zero external dependencies
- Data sovereignty: No API calls, no cloud services, no cross-border transfers
- Air-gapped capable: Deploy in fully isolated environments if required
- Regulatory-grade accuracy: Supporting Expert Determination standards
- HIPAA and GDPR compliance across languages, without compliance gaps.
Use Cases
- Hospital EHR systems: Automated patient record de-identification
- Clinical research: Multilingual dataset preparation for studies
- Insurance companies: Claims processing across
https://huggingface.co/collections/OpenMed/multilingual-pii-and-de-identification
- 1 reply
MaziyarPanahi
posted an update 2 months ago
Post
1315
From Golden Gate Bridge to Broken JSON: Why Anthropic's SAE Steering Fails for Structured Output
I ran 6 experiments trying to use Anthropic's SAE steering for JSON generation.
- Base model: 86.8% valid JSON
- Steering only: 24.4%
- Fine-tuned: 96.6%
- FSM constrained: 100%
Steering is for semantics, not syntax.
https://huggingface.co/blog/MaziyarPanahi/sae-steering-json
I ran 6 experiments trying to use Anthropic's SAE steering for JSON generation.
- Base model: 86.8% valid JSON
- Steering only: 24.4%
- Fine-tuned: 96.6%
- FSM constrained: 100%
Steering is for semantics, not syntax.
https://huggingface.co/blog/MaziyarPanahi/sae-steering-json
MaziyarPanahi
posted an update 2 months ago
Post
4062
🚨 Day 8/8: OpenMed Medical Reasoning Dataset Release - THE GRAND FINALE
Today I complete my 8-day release series with Medical-Reasoning-SFT-Mega.
The largest open medical reasoning dataset, combining 7 state-of-the-art AI models with fair distribution deduplication.
THE 7 SOURCE MODELS (Original Sample Counts):
1. Trinity-Mini: 810,284 samples
2. Qwen3-Next-80B: 604,249 samples
3. GPT-OSS-120B: 506,150 samples
4. Nemotron-Nano-30B: 444,544 samples
5. GLM-4.5-Air: 225,179 samples
6. MiniMax-M2.1: 204,773 samples
7. Baichuan-M3-235B: 124,520 samples
TOTAL BEFORE DEDUPLICATION: 2,919,699 samples
TOKEN COUNTS:
- Content tokens: 2.22 Billion
- Reasoning tokens: 1.56 Billion
- Total tokens: 3.78 Billion
- Samples with chain-of-thought: 100%
Quick Start:
All datasets Apache 2.0 licensed. Free for research and commercial use.
Thank you for following OpenMed's release series. I can't wait to see what you build. 🔥
OpenMed/Medical-Reasoning-SFT-Mega
OpenMed/Medical-Reasoning-SFT-GPT-OSS-120B-V2
OpenMed/Medical-Reasoning-SFT-Trinity-Mini
OpenMed/Medical-Reasoning-SFT-GLM_4.5_Air
OpenMed/Medical-Reasoning-SFT-MiniMax-M2.1
OpenMed/Medical-Reasoning-SFT-Qwen3-Next-80B
OpenMed/Medical-Reasoning-SFT-Nemotron-Nano-30B
OpenMed/Medical-Reasoning-SFT-Baichuan-M3-235B
https://huggingface.co/collections/OpenMed/medical-datasets
Today I complete my 8-day release series with Medical-Reasoning-SFT-Mega.
The largest open medical reasoning dataset, combining 7 state-of-the-art AI models with fair distribution deduplication.
THE 7 SOURCE MODELS (Original Sample Counts):
1. Trinity-Mini: 810,284 samples
2. Qwen3-Next-80B: 604,249 samples
3. GPT-OSS-120B: 506,150 samples
4. Nemotron-Nano-30B: 444,544 samples
5. GLM-4.5-Air: 225,179 samples
6. MiniMax-M2.1: 204,773 samples
7. Baichuan-M3-235B: 124,520 samples
TOTAL BEFORE DEDUPLICATION: 2,919,699 samples
TOKEN COUNTS:
- Content tokens: 2.22 Billion
- Reasoning tokens: 1.56 Billion
- Total tokens: 3.78 Billion
- Samples with chain-of-thought: 100%
Quick Start:
from datasets import load_dataset
ds = load_dataset("OpenMed/Medical-Reasoning-SFT-Mega")All datasets Apache 2.0 licensed. Free for research and commercial use.
Thank you for following OpenMed's release series. I can't wait to see what you build. 🔥
OpenMed/Medical-Reasoning-SFT-Mega
OpenMed/Medical-Reasoning-SFT-GPT-OSS-120B-V2
OpenMed/Medical-Reasoning-SFT-Trinity-Mini
OpenMed/Medical-Reasoning-SFT-GLM_4.5_Air
OpenMed/Medical-Reasoning-SFT-MiniMax-M2.1
OpenMed/Medical-Reasoning-SFT-Qwen3-Next-80B
OpenMed/Medical-Reasoning-SFT-Nemotron-Nano-30B
OpenMed/Medical-Reasoning-SFT-Baichuan-M3-235B
https://huggingface.co/collections/OpenMed/medical-datasets
- 6 replies
MaziyarPanahi
posted an update 3 months ago
Post
3760
🎉 OpenMed 2025 Year in Review: 6 Months of Open Medical AI
I'm thrilled to share what the OpenMed community has accomplished since our July 2025 launch!
📊 The Numbers
29,700,000 downloads Thank you! 🙏
- 481 total models (475 medical NER models + 6 fine-tuned LLMs)
- 475 medical NER models in [OpenMed](
OpenMed ) organization
- 6 fine-tuned LLMs in [openmed-community](
openmed-community )
- 551,800 PyPI downloads of the [openmed package](https://pypi.org/project/openmed/)
- 707 followers on HuggingFace (you!)
- 97 GitHub stars on the [toolkit repo](https://github.com/maziyarpanahi/openmed)
🏆 Top Models by Downloads
1. [OpenMed-NER-PharmaDetect-SuperClinical-434M]( OpenMed/OpenMed-NER-PharmaDetect-SuperClinical-434M) — 147,305 downloads
2. [OpenMed-NER-ChemicalDetect-ElectraMed-33M]( OpenMed/OpenMed-NER-ChemicalDetect-ElectraMed-33M) — 126,785 downloads
3. [OpenMed-NER-BloodCancerDetect-TinyMed-65M]( OpenMed/OpenMed-NER-BloodCancerDetect-TinyMed-65M) — 126,465 downloads
🔬 Model Categories
Our 481 models cover comprehensive medical domains:
- Disease Detection (~50 variants)
- Pharmaceutical Detection (~50 variants)
- Oncology Detection (~50 variants)
- Genomics/DNA Detection (~80 variants)
- Chemical Detection (~50 variants)
- Species/Organism Detection (~60 variants)
- Protein Detection (~50 variants)
- Pathology Detection (~50 variants)
- Blood Cancer Detection (~30 variants)
- Anatomy Detection (~40 variants)
- Zero-Shot NER (GLiNER-based)
OpenMed
OpenMed NER: Open-Source, Domain-Adapted State-of-the-Art Transformers for Biomedical NER Across 12 Public Datasets (2508.01630)
https://huggingface.co/collections/OpenMed/medical-and-clinical-ner
https://huggingface.co/collections/OpenMed/zeroshot-medical-and-clinical-ner
OpenMed/Medical-Reasoning-SFT-GPT-OSS-120B
I'm thrilled to share what the OpenMed community has accomplished since our July 2025 launch!
📊 The Numbers
29,700,000 downloads Thank you! 🙏
- 481 total models (475 medical NER models + 6 fine-tuned LLMs)
- 475 medical NER models in [OpenMed](
- 6 fine-tuned LLMs in [openmed-community](
- 551,800 PyPI downloads of the [openmed package](https://pypi.org/project/openmed/)
- 707 followers on HuggingFace (you!)
- 97 GitHub stars on the [toolkit repo](https://github.com/maziyarpanahi/openmed)
🏆 Top Models by Downloads
1. [OpenMed-NER-PharmaDetect-SuperClinical-434M]( OpenMed/OpenMed-NER-PharmaDetect-SuperClinical-434M) — 147,305 downloads
2. [OpenMed-NER-ChemicalDetect-ElectraMed-33M]( OpenMed/OpenMed-NER-ChemicalDetect-ElectraMed-33M) — 126,785 downloads
3. [OpenMed-NER-BloodCancerDetect-TinyMed-65M]( OpenMed/OpenMed-NER-BloodCancerDetect-TinyMed-65M) — 126,465 downloads
🔬 Model Categories
Our 481 models cover comprehensive medical domains:
- Disease Detection (~50 variants)
- Pharmaceutical Detection (~50 variants)
- Oncology Detection (~50 variants)
- Genomics/DNA Detection (~80 variants)
- Chemical Detection (~50 variants)
- Species/Organism Detection (~60 variants)
- Protein Detection (~50 variants)
- Pathology Detection (~50 variants)
- Blood Cancer Detection (~30 variants)
- Anatomy Detection (~40 variants)
- Zero-Shot NER (GLiNER-based)
OpenMed NER: Open-Source, Domain-Adapted State-of-the-Art Transformers for Biomedical NER Across 12 Public Datasets (2508.01630)
https://huggingface.co/collections/OpenMed/medical-and-clinical-ner
https://huggingface.co/collections/OpenMed/zeroshot-medical-and-clinical-ner
OpenMed/Medical-Reasoning-SFT-GPT-OSS-120B
- 1 reply
Goekdeniz-Guelmez
authored a
paper 4 months ago
MaziyarPanahi
authored 2
papers 8 months ago
MaziyarPanahi
posted an update 9 months ago
Post
13035
🧬 Breaking news in Clinical AI: Introducing the OpenMed NER Model Discovery App on Hugging Face 🔬
OpenMed is back! 🔥 Finding the right biomedical NER model just became as precise as a PCR assay!
I'm thrilled to unveil my comprehensive OpenMed Named Entity Recognition Model Discovery App that puts 384 specialized biomedical AI models at your fingertips.
🎯 Why This Matters in Healthcare AI:
Traditional clinical text mining required hours of manual model evaluation. My Discovery App instantly connects researchers, clinicians, and data scientists with the exact NER models they need for their biomedical entity extraction tasks.
🔬 What You Can Discover:
✅ Pharmacological Models - Extract "chemical compounds", "drug interactions", and "pharmaceutical" entities from clinical notes
✅ Genomics & Proteomics - Identify "DNA sequences", "RNA transcripts", "gene variants", "protein complexes", and "cell lines"
✅ Pathology & Disease Detection - Recognize "pathological formations", "cancer types", and "disease entities" in medical literature
✅ Anatomical Recognition - Map "anatomical systems", "tissue types", "organ structures", and "cellular components"
✅ Clinical Entity Extraction - Detect "organism species", "amino acids", 'protein families", and "multi-tissue structures"
💡 Advanced Features:
🔍 Intelligent Entity Search - Find models by specific biomedical entities (e.g., "Show me models detecting CHEM + DNA + Protein")
🏥 Domain-Specific Filtering - Browse by Oncology, Pharmacology, Genomics, Pathology, Hematology, and more
📊 Model Architecture Insights - Compare BERT, RoBERTa, and DeBERTa implementations
⚡ Real-Time Search - Auto-filtering as you type, no search buttons needed
🎨 Clinical-Grade UI - Beautiful, intuitive interface designed for medical professionals
Ready to revolutionize your biomedical NLP pipeline?
🔗 Try it now: OpenMed/openmed-ner-models
🧬 Built with: Gradio, Transformers, Advanced Entity Mapping
OpenMed is back! 🔥 Finding the right biomedical NER model just became as precise as a PCR assay!
I'm thrilled to unveil my comprehensive OpenMed Named Entity Recognition Model Discovery App that puts 384 specialized biomedical AI models at your fingertips.
🎯 Why This Matters in Healthcare AI:
Traditional clinical text mining required hours of manual model evaluation. My Discovery App instantly connects researchers, clinicians, and data scientists with the exact NER models they need for their biomedical entity extraction tasks.
🔬 What You Can Discover:
✅ Pharmacological Models - Extract "chemical compounds", "drug interactions", and "pharmaceutical" entities from clinical notes
✅ Genomics & Proteomics - Identify "DNA sequences", "RNA transcripts", "gene variants", "protein complexes", and "cell lines"
✅ Pathology & Disease Detection - Recognize "pathological formations", "cancer types", and "disease entities" in medical literature
✅ Anatomical Recognition - Map "anatomical systems", "tissue types", "organ structures", and "cellular components"
✅ Clinical Entity Extraction - Detect "organism species", "amino acids", 'protein families", and "multi-tissue structures"
💡 Advanced Features:
🔍 Intelligent Entity Search - Find models by specific biomedical entities (e.g., "Show me models detecting CHEM + DNA + Protein")
🏥 Domain-Specific Filtering - Browse by Oncology, Pharmacology, Genomics, Pathology, Hematology, and more
📊 Model Architecture Insights - Compare BERT, RoBERTa, and DeBERTa implementations
⚡ Real-Time Search - Auto-filtering as you type, no search buttons needed
🎨 Clinical-Grade UI - Beautiful, intuitive interface designed for medical professionals
Ready to revolutionize your biomedical NLP pipeline?
🔗 Try it now: OpenMed/openmed-ner-models
🧬 Built with: Gradio, Transformers, Advanced Entity Mapping
- 5 replies
khang119966
authored a
paper over 1 year ago
Post
5047
nanoLLaVA-1.5 is here! Same size (1B), better performance 🔥🔥🔥
And it is much more powerful than v1.0
Try it out now on HF Spaces: qnguyen3/nanoLLaVA
Model: qnguyen3/nanoLLaVA-1.5
And it is much more powerful than v1.0
Try it out now on HF Spaces: qnguyen3/nanoLLaVA
Model: qnguyen3/nanoLLaVA-1.5
- 3 replies
Post
6400
🎉 Introducing nanoLLaVA, a powerful multimodal AI model that packs the capabilities of a 1B parameter vision language model into just 5GB of VRAM. 🚀 This makes it an ideal choice for edge devices, bringing cutting-edge visual understanding and generation to your devices like never before. 📱💻
Model: qnguyen3/nanoLLaVA 🔍
Spaces: qnguyen3/nanoLLaVA (thanks to @merve )
Under the hood, nanoLLaVA is based on the powerful vilm/Quyen-SE-v0.1 (my Qwen1.5-0.5B finetune) and Google's impressive google/siglip-so400m-patch14-384. 🧠 The model is trained using a data-centric approach to ensure optimal performance. 📊
In the spirit of transparency and collaboration, all code and model weights are open-sourced under the Apache 2.0 license. 🤝
Model: qnguyen3/nanoLLaVA 🔍
Spaces: qnguyen3/nanoLLaVA (thanks to @merve )
Under the hood, nanoLLaVA is based on the powerful vilm/Quyen-SE-v0.1 (my Qwen1.5-0.5B finetune) and Google's impressive google/siglip-so400m-patch14-384. 🧠 The model is trained using a data-centric approach to ensure optimal performance. 📊
In the spirit of transparency and collaboration, all code and model weights are open-sourced under the Apache 2.0 license. 🤝
- 1 reply
qnguyen3
authored a
paper over 2 years ago