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# QUESTIONS Diagnosis/Staging
What benefit to clinical management does positron emission tomography (PET) or positron emission tomography/computed tomography (PET/CT) contribute to the diagnosis or staging of head and neck cancer? What benefit to clinical management does PET or PET/CT contribute to the assessment of tr... |
# GUIDELINE OBJECTIVES
To update clinical guidance on the use of multigene profiling assays in individuals with earlystage invasive breast cancer.
# TARGET POPULATION
Individuals diagnosed with early-stage invasive breast cancer for whom further information is needed for prognosis and treatment decision making. In thi... |
# GUIDELINE OBJECTIVES
To make recommendations with respect to the use of T2-weighted magnetic resonance imaging (MRI) ± functional sequences in the pre-treatment local staging of patients with newly diagnosed prostate cancer.
- MRI refers to T2-weighted MRI.
- Functional sequences include dynamic contrast-enhanced ima... |
Evidence-Based Series 4-5 is CURRENT as of November 2022. In June 2016 a literature search and review determined that the recommendations were still valid and not causing harm but all relevant aspects of the topic were not covered by the original guideline. This document was identified for an UPDATE but it is anticipat... |
# GUIDELINE OBJECTIVES
To make recommendations with respect to the role of adjuvant systemic chemotherapy in stage II and III colon cancer patients who have undergone complete resection with curative intent.
# TARGET POPULATION
The target population consists of adult patients with stage II and III colon cancer who hav... |
# Section 1:
Recommendations Section 2:
Recommendations and Key Evidence Section 3: Guideline Methods Overview Section 4: Systematic Review Section 5:
Internal and External Review
For information about this document, please contact Alex Sun, the lead author, through the PEBC via: Phone: 905-527-4322 ext. 42822 Fax: 905... |
These guideline recommendations have been ENDORSED, which means that the recommendations are still current and relevant for decision making.# GUIDELINE OBJECTIVE
How should patients presenting to family physicians and other primary care providers (PCPs) with signs and/or symptoms of prostate cancer, including incidenta... |
To jointly update the Cancer Care Ontario guideline on brachytherapy for patients with prostate cancer to account for new evidence.An Update Panel conducted a targeted systematic literature review and identified more recent randomized controlled trials comparing dose-escalated external beam radiation therapy (EBRT) wit... |
In Canada in 2010, an estimated 2600 new cases of ovarian cancer will be diagnosed and, of those cases, 1750 women will die, making ovarian cancer the seventh most prevalent form of cancer in Canadian women and their fifth leading cause of cancer death (1). Women with ovarian cancer typically have subtle, non-specific ... |
To determine the risk of cutaneous malignant melanoma (herein referred to as melanoma) associated with use of indoor tanning devices, including impact of age at first use and frequency of use on the relative risk of developing melanoma.
# TARGET POPULATION
All users of indoor tanning beds are the target population of ... |
# RECOMMENDATIONS, KEY EVIDENCE, AND JUSTIFICATION
RECOMMENDATION 1 DNMT3A mutation testing should be included as a biomarker test in cytogenetically normal AML patients.
# Summary of Key Evidence for Recommendation
Four (8,10,13,15) of the eight studies (8)(9)(10)(11)(12)(13)(14)(15) included in the systematic review... |
# TARGET POPULATION
All adult MM patients considered for treatment that includes blood or marrow transplantation.
# RECOMMENDATIONS AND SUPPORTING EVIDENCE
Autologous SCT is the recommended treatment option for patients with newly diagnosed MM, as part of the initial treatment plan.
# Supporting evidence
Evidence inc... |
# GUIDELINE OBJECTIVES
# INTENDED USERS
This guideline is intended for provincial policy makers, primary care physicians, nurse practitioners, radiologists, respirologists, thoracic surgeons, thoracic oncologists, and any health professionals involved with patients who may be at risk for developing lung cancer.
# REC... |
# INTENDED PURPOSE
- This recommendation report is primarily intended to guide the Ontario PET Steering Committee in their decision making concerning indications for the use of PET imaging. - This recommendation report may also be useful in informing clinical decision making regarding the appropriate role of PET imagin... |
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