| ====================================================================== |
| HLT-003 SIMULATION ENGINE — AUDIT LOG |
| XpertSystems.ai · Synthetic Data Factory |
| ====================================================================== |
| Generated: 2026-05-17 13:32:31 UTC |
| Engine Version: 1.0 |
| Trial ID: HLT003-ONC-TTE-001 |
| Therapeutic Area: Oncology |
| Trial Phase: II |
| Endpoint Type: TTE |
| Seed: 42 |
| N Participants: 600 |
| N Arms: 2 |
| Elapsed: 0.05s |
|
|
| ARM CONFIGURATION |
| ---------------------------------------- |
| Arm 0: SoC Chemotherapy | d=0.00 | AE mult=1.0 |
| Arm 1: Targeted Therapy | d=0.30 | AE mult=1.3 |
|
|
| RESULTS SUMMARY |
| ---------------------------------------- |
| Arm 0 [SoC Chemotherapy]: |
| n = 301 |
| Dropout = 8.6% |
| Events = 180 (59.8%) |
| AEs (mean) = 4.7 |
| Grade 3+ AEs (mean) = 1.9 |
| SAEs (mean) = 1.00 |
| Arm 1 [Targeted Therapy]: |
| n = 299 |
| Dropout = 8.4% |
| Events = 160 (53.5%) |
| AEs (mean) = 6.1 |
| Grade 3+ AEs (mean) = 2.9 |
| SAEs (mean) = 1.64 |
|
|
| REPRODUCIBILITY |
| ---------------------------------------- |
| Re-run command: python hlt003_simulation_engine.py --seed 42 |
| All outputs are deterministic with this seed. |
|
|
| OUTPUT FILES |
| ---------------------------------------- |
| /home/claude/hlt003_work/hlt003_sample/oncology_pfs_trial.csv |
| trial_config_schema.json |
| simulation_audit_log.txt |
| ====================================================================== |
