pmc stringlengths 9 14 | journal stringlengths 3 231 | title stringlengths 4 1.59k | pub_date stringlengths 8 10 | abstract stringlengths 0 33.9k | paragraphs listlengths 0 12.8k |
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PMC10521587 | Cureus | Eosinophilic Enteritis Flare-Up Mimicking Acute Gastroenteritis: A Rare Case | 27-08-2023 | Eosinophilic enteritis is a rare subset of eosinophilic gastrointestinal disorders. It typically presents with chronic symptoms of abdominal pain, nausea, vomiting, diarrhea, and ascites. However, the clinical presentation can vary due to acute flare-ups. Here, we present a case of eosinophilic enteritis in a young fem... | [
"Eosinophilic gastrointestinal by its association with GI symptoms and eosinophil-rich infiltration of the intestinal mucosa, without secondary intestinal eosinophilia [ ]. After eosinophilic esophagitis, both eosinophilic gastroenteritis and EE represent the most frequent subset of disorders [ ]. Although the dise... |
PMC10813894 | Children | Statins—Beyond Their Use in Hypercholesterolemia: Focus on the Pediatric Population | 17-01-2024 | Statins are a class of medications primarily used in adults to lower cholesterol levels and reduce the risk of cardiovascular events. However, the use of statins in children is generally limited and carefully considered despite the well-documented anti-inflammatory, anti-angiogenic, and pro-apoptotic effects, as well a... | [
"Statins primarily function by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A primarily due to elevated LDL cholesterol, can be attributed to the cumulative effect of multiple single nucleotide variants scattered throughout the genome [ ]. These individuals are at a high risk of developing atherosclerosis due to ... |
PMC10137892 | Gels | Nano-Gels: Recent Advancement in Fabrication Methods for Mitigation of Skin Cancer | 13-04-2023 | In the 21st century, melanoma and non-melanoma skin cancers have become an epidemic outbreak worldwide. Therefore, the exploration of all potential preventative and therapeutic measures based on either physical or bio-chemical mechanisms is essential via understanding precise pathophysiological pathways (Mitogen-activa... | [
"The concept “novel drug delivery system” into different categories such as physically-chemically cross-linked, hybrid nano-gel, polymeric, bio-mimetic nano-gel, pH, thermo, magnetic, hypoxia, ultrasound, enzyme, and reduction responsive nano-gel on the basis of synthesis procedure, nature of materials used and res... |
PMC10369066 | Frontiers in Immunology | Gut colonization with an obesity-associated enteropathogenic microbe modulates the premetastatic niches to promote breast cancer lung and liver metastasis | 12-07-2023 | Introduction Obesity, an independent risk factor for breast cancer growth and metastatic progression, is also closely intertwined with gut dysbiosis; and both obese state and dysbiosis promote each other. Enteric abundance of Bacteroides fragilis is strongly linked with obesity, and we recently discovered the presence ... | [
"The impact of obesity on breast cancer can be appreciated by the fact that a 5-unit increase in body mass index. Adiposity and altered body fat composition can significantly influence breast cancer outcomes through an upsurge of proinflammatory cytokines and immune modulation. Likewise, dysbiotic gut microbiota ca... |
PMC10785397 | BMC Health Services Research | Causes and consequences of quack medicine in health care: a scoping review of global experience | 11-01-2024 | Background The field of health has been facing challenges with fraudulent practices and the prevalence of “quack medicine”. Many cases have given rise to this issue. Therefore, this study aims to comprehensively investigate and categorize the causes and consequences of quack medicine in the healthcare. Methods A scopin... | [
"Issues such as quackery and charlatanism have long been a concern for human civilizations and communities since the development of health service delivery structures and processes. While the forms and severity of these issues may vary across nations, it can be argued that all health systems are susceptible to some... |
PMC10350961 | The Journal of Physical Chemistry Letters | Bond Polarizability as a Probe of Local Crystal Fields
in Hybrid Lead-Halide Perovskites | 05-07-2023 | A rotating organic
cation and a dynamically disordered soft inorganic
cage are the hallmark features of organic-inorganic lead-halide perovskites.
Understanding the interplay between these two subsystems is a challenging
problem, but it is this coupling that is widely conjectured to be
responsible for the unique behavi... | [
"The efficiency\nof hybrid organic-inorganic\nlead-halide perovskite. The main reason for this choice is\nthat these modes are by far the strongest in terms of IR-intensity.^(17 , 30 , 41) Elementary counting of the degrees\nof freedom reveals. In C we show how the. To relate it to the polarizability\n⟨ α^(H) ⟩ mea... |
PMC10500542 | Cureus | Hand Scrubbing and Donning of Sterile Surgical Gloves: An Observational Clinical Audit of Novice Dental Surgeons | 15-08-2023 | Background The most critical factors in the satisfactory recovery of a patient post-surgery are obedience to sterilization and aseptic protocol. Using aseptic principles, the standard hand scrubbing and gloving procedure prevents contamination of the surgical site and aids in infection control. Methods Eighty dental in... | [
"Prevention of surgical site infections is critical for evaluating control mechanisms within healthcare systems and implementing the necessary changes. However, such monitoring can be costly, posing an enormous problem to healthcare systems around the world, particularly in impoverished countries [ ].",
"Putting ... |
PMC10757273 | Clinics | Preliminary outcomes of five-year survival for ovarian malignancies in profiled Serbian Oncology Centre | 04-05-2023 | Highlights • Analyzing predictors of survival in patients with ovarian carcinoma is crucial. • Independent estimators of mortality in ovarian carcinoma, are more precise by identifying histopathologic tumor grade, FIGO, and NACT. • The aforementioned predictors also involve the number of therapeutic cycles, type of sur... | [
"With the aging of the world's population, the authors are faced with changes in morbidity and mortality causes and cancer is becoming the leading cause of death. It is estimated that in the continent of Europe, which counts close to 10% of the world's population, there are about 23.4% newly diagnosed cancers and a... |
PMC10603682 | Animals : an Open Access Journal from MDPI | Hepatitis E Virus in Livestock—Update on Its Epidemiology and Risk of Infection to Humans | 17-10-2023 | Simple Summary Hepatitis E virus (HEV) is a public health problem worldwide, as it is an important food pathogen that humans can obtain from animals. The most common way to infect humans is by consuming contaminated, undercooked meat or raw meat from infected pigs. However, domestic cattle, small ruminants such as shee... | [
"Hepatitis E is an important public health problem worldwide. The World Health Organization estimates that 20 million infections with Paslahepevirus balayani have higher HEV-related seroprevalence rates than the general population [ ]. All livestock professionals should be aware of the risk of zoonotic-acquired hep... |
PMC10752250 | Ecology and Evolution | Between‐year and spatial variation in body condition across the breeding cycle in a pelagic seabird, the Red‐billed Tropicbird | 27-12-2023 | Abstract Body condition in pelagic seabirds impacts key fitness‐related traits such as reproductive performance and breeding frequency. Regulation of body condition can be especially important for species with long incubation periods and long individual incubation shifts between foraging trips. Here, we show that body ... | [
"Body condition in birds is a key factor underlying the success of breeding, migration and moult. In seabirds, parental body condition is known to influence and impact breeding and foraging regimes. In pelagic seabirds, spending much of their time at sea and only returning to land to breed, it is challenging to und... |
PMC10246788 | PLOS ONE | Trace quantification of GL-V9 and its glucuronide metabolites (5-O-glucuronide GL-V9) in Beagle dog plasma by UPLC–MS/MS and its application to a pharmacokinetic study | 07-06-2023 | GL-V9, a new synthetic flavonoid derived from wogonin, has shown beneficial biological functions. In this study, accurate and sensitive UPLC–MS/MS methods were developed and validated for the quantification of GL-V9 and its glucuronide metabolite (5-O-glucuronide GL-V9) in Beagle dog plasma. The chromatographic separat... | [
"Cancer, the abnormal growth of cells, is an enigmatic and frightening disease or group of diseases that places an enormous burden on society worldwide. Cancer occurs with the involvement of a variety of factors, genes, and pathways and shows multiple stages [ , ]. In recent years, advances such as exploring molecu... |
PMC10754979 | Frontiers in Neuroscience | TSPNet: a time-spatial parallel network for classification of EEG-based multiclass upper limb motor imagery BCI | 15-12-2023 | The classification of electroencephalogram (EEG) motor imagery signals has emerged as a prominent research focus within the realm of brain-computer interfaces. Nevertheless, the conventional, limited categories (typically just two or four) offered by brain-computer interfaces fail to provide an extensive array of contr... | [
"Brain-computer interface. Among various techniques, electroencephalography. A multitude of algorithms have been developed for EEG pattern classification in diverse BCI applications. In their research, Wang et al. redefined the common spatial pattern proposed a deep learning framework that incorporates convolutiona... |
PMC10372701 | JAMA Network Open | Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People | 26-07-2023 | The secondary analysis of a randomized clinical trial investigates the effect of low-dose aspirin on incidence of ischemic stroke and intracranial bleeding among healthy older people. | [
"Aspirin is an antiplatelet agent that has been used in low doses",
"People aged 70 years or older. A total of 9525 participants were allocated to aspirin and 9589 participants to placebo. At baseline, randomized treatment groups were well matched in demographic and risk factors for stroke.^(21)",
"During follo... |
PMC10152627 | Journal of Neuroinflammation | Role of macrophage autophagy in postoperative pain and inflammation in mice | 02-05-2023 | Background Postoperative pain and inflammation are significant complications following surgery. Strategies that aim to prevent excessive inflammation without hampering natural wound-healing are required for the management of postoperative pain and inflammation. However, the knowledge of the mechanisms and target pathwa... | [
"Postoperative pain is one of the most significant post-surgical complications and can delay functional recovery and impair patients’ quality of life. Inflammation plays crucial roles in the pathophysiology of postoperative pain. Once tissue damage occurs from surgical intervention, inflammatory cells proliferate a... |
PMC10995625 | Microbial Genomics | Optimising machine learning prediction of minimum inhibitory concentrations in Klebsiella pneumoniae | 26-03-2024 | Abstract Minimum Inhibitory Concentrations (MICs) are the gold standard for quantitatively measuring antibiotic resistance. However, lab-based MIC determination can be time-consuming and suffers from low reproducibility, and interpretation as sensitive or resistant relies on guidelines which change over time. Genome se... | [
"The scripts used to run and fit the models can be found athttps://github.com/gbatbiff/Kpneu_MIC_prediction. The Illumina sequences from Thorpe et al . are available from the European Nucleotide Archive under accession PRJEB27342 . All the other strains are available on https://www.bv-brc.org/ database.",
"Klebsi... |
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