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A highly convergent and effective synthesis of the phytoalexin elicitor hexasaccharide.
The peracetylated hexasaccharide 1,2,4-tri-O-acetyl-3-O-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-6- O- (2,3,4-tri-O-acetyl-6-O-(2,4-di-O-acetyl-3,6-di-O-(2,3,4,6-tetra-O-acety l- beta-D-glucopyranosyl)-beta-D-glucopyranosyl)-b... | {
"pile_set_name": "PubMed Abstracts"
} |
Microsatellites, single nucleotide polymorphisms and a sequence tagged site in starch-synthesizing genes in relation to starch physicochemical properties in nonwaxy rice (Oryza sativa L.).
Starch characteristics determine the quality of various products of rice, e.g., eating, cooking and processing qualities. Our previ... | {
"pile_set_name": "PubMed Abstracts"
} |
[Cytotoxicity of dendritic cells pulsed by CpG ODN on ovarian carcinoma cells: in vitro experiment with ovarian carcinoma cells].
To investigate the effect of dendritic cells (DCs) pulsed by oligonucleotide containing "un-methylated cytimidine-phosphodiester bond-guanylic acid" motif (CpG ODN) on ovarian carcinoma cell... | {
"pile_set_name": "PubMed Abstracts"
} |
Autoantibody profile and clinical patterns in 619 Italian patients with cutaneous lupus erythematosus.
Anti-nuclear antibodies (ANA), anti-extractable nuclear antigens (ENA) and anti-dsDNA antibodies are often associated with cutaneous lupus erythematosus (CLE), with variable frequency depending on skin subtype. Howeve... | {
"pile_set_name": "PubMed Abstracts"
} |
Sulfated oligosaccharides isolated from the respiratory mucins of a secretor patient suffering from chronic bronchitis.
The most acidic carbohydrate chains released by alkaline borohydride treatment of the bulk of airway mucins secreted by a patient (blood group O, secretor) suffering from a mildly infected chronic bro... | {
"pile_set_name": "PubMed Abstracts"
} |
Strain variation of immature female rats in response to various superovulatory hormone preparations and routes of administration.
The purpose of this study was to examine the response of rats of different genetic backgrounds to various superovulatory hormonal treatments. Immature Sprague Dawley (SD), FBNF1, and F344 fe... | {
"pile_set_name": "PubMed Abstracts"
} |
[Correlation between positive reaction point of auricular points and stroke].
To explore the auricular point specificity of the electric determination in stroke so as to provide the evidence for the objective study on the auricular point diagnosis in stroke. Thirty patients of stroke were selected in an observation gro... | {
"pile_set_name": "PubMed Abstracts"
} |
Intramolecular alkyl phosphine dehydrogenation in cationic rhodium complexes of tris(cyclopentylphosphine).
[Rh(nbd)(PCyp(3))(2)][BAr(F) (4)] (1) [nbd = norbornadiene, Ar(F) = C(6)H(3)(CF(3))(2), PCyp(3) = tris(cyclopentylphosphine)] spontaneously undergoes dehydrogenation of each PCyp(3) ligand in CH(2)Cl(2) solution ... | {
"pile_set_name": "PubMed Abstracts"
} |
[Impact of chronic aluminum exposure on NMDAR1 in the cortex and peripheral blood lymphocytes in rats].
To study the impact of the chronic aluminum exposure on Nmethyl-D-aspartate receptor 1( NMDAR1) in the cortex and peripheral blood, and to explore the possibility that whether NMDAR1 of peripheral blood lymphocytes c... | {
"pile_set_name": "PubMed Abstracts"
} |
Light-Driven Proton, Sodium Ion, and Chloride Ion Transfer Mechanisms in Rhodopsins: SAC-CI Study.
Bacteriorhodopsin (BR) and halorhodopsin (HR) are well-known light-driven ion-pumping rhodopsins. BR transfers a proton from the intracellular medium to the extracellular medium. HR takes in chloride ion from the extracel... | {
"pile_set_name": "PubMed Abstracts"
} |
A strategy for the design of membrane-permeable folypoly-gamma-glutamate synthetase inhibitors: "bay-region"-substituted 2-desamino-2-methyl-5,8-dideazafolate analogs.
Previous attempts to design inhibitors of mammalian folylpolyglutamate synthetase (FPGS) have resulted in three classes of active compounds, all of whic... | {
"pile_set_name": "PubMed Abstracts"
} |
MiR-146 regulates the repair and regeneration of intervertebral nucleus pulposus cells via Notch1 pathway.
The aim of this study was to investigate the effects of regulation of micro-ribonucleic acid (miR)-146 expression targeting the Notch1 pathway on the repair and regeneration of intervertebral nucleus pulposus cell... | {
"pile_set_name": "PubMed Abstracts"
} |
Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes.
The cytosolic fraction of human polymorphonuclear leukocytes precipitated with 60% ammonium sulfate produced 5-lipoxygenase products fro... | {
"pile_set_name": "PubMed Abstracts"
} |
Interleukin 1-stimulated prostacyclin synthesis in endothelium: lack of phospholipase C, phospholipase D, or protein kinase C involvement in early signal transduction.
The cascade of transmembrane signaling events that follow the occupancy of the interleukin 1 receptor remain poorly defined. We examined potential postr... | {
"pile_set_name": "PubMed Abstracts"
} |
Ion-deficient environment induces the expression of basolateral chloride channel, ClC-3-like protein, in gill mitochondrion-rich cells for chloride uptake of the tilapia Oreochromis mossambicus.
Gill mitochondrion-rich (MR) cells contain different molecules to carry out functionally distinct mechanisms. To date, the pu... | {
"pile_set_name": "PubMed Abstracts"
} |
Apolipoprotein B-containing lipoproteins in renal failure: the relation to mode of dialysis.
The aim of this study was to establish whether there is a differential effect of mode of dialysis, hemodialysis (HD), or continuous ambulatory peritoneal dialysis (CAPD) on the dyslipidemia of renal failure. The lipoprotein pro... | {
"pile_set_name": "PubMed Abstracts"
} |
Glycine transport by hemolysed and restored pigeon red cells. Effects of a Donnan-induced electrical potential on entry and exit kinetics.
The influence of a Donnan effect on the transport of glycine by hemolysed and restored pigeon red cells was examined. The Donnan effect was produced by replacing Cl- with 2,4-toluen... | {
"pile_set_name": "PubMed Abstracts"
} |
Turning on red and near-infrared phosphorescence in octahedral complexes with metalated quinones.
We report the synthesis of π-bonded ruthenium, rhodium, and iridium o-benzoquinones [Cp*M(o-C(6)H(4)O(2))](n) [M = Ru (2), n = 1-; Rh (3), n = 0; Ir (4), n = 0] following a novel synthetic procedure. Compounds 2-4 were ful... | {
"pile_set_name": "PubMed Abstracts"
} |
Treatment of atherosclerotic ostial renal artery stenosis with the intravascular stent.
Traditional approaches to revascularization for atherosclerotic ostial renal artery stenosis (RAS) have been suboptimal because of the invasiveness and relatively high perioperative morbidity and mortality of surgery and the low rat... | {
"pile_set_name": "PubMed Abstracts"
} |
Selectivity in the modification of the alpha-amino groups of hemoglobin on reductive alkylation with aliphatic carbonyl compounds. Influence of derivatization on the polymerization of hemoglobin S.
The reactivity of the alpha-amino groups of the alpha- and beta-chains of hemoglobn toward reductive alkylation using limi... | {
"pile_set_name": "PubMed Abstracts"
} |
Streptomyces iconiensis sp. nov. and Streptomyces smyrnaeus sp. nov., two halotolerant actinomycetes isolated from a salt lake and saltern.
The taxonomic positions of two novel actinomycetes, designated strains BNT558(T) and SM3501(T), were established by using a polyphasic approach. The organisms had chemical and morp... | {
"pile_set_name": "PubMed Abstracts"
} |
Expression patterns of hepatic genes involved in lipid metabolism in cows with subclinical or clinical ketosis.
Dairy cows with ketosis are characterized by high blood concentrations of ketone bodies and hepatic lipid metabolism disorder. The discrepancies in the abundance of mRNA encoding a variety of hepatic candidat... | {
"pile_set_name": "PubMed Abstracts"
} |
[Angiotensin II activates large-conductance Ca(2+)-activated potassium channels in human mesenteric artery smooth muscle cells].
The aim of present study was to explore the vasodilatation mechanism of angiotensin II (AngII) at the molecular level by investigating the effect of AngII on large-conductance Ca²⁺-activated ... | {
"pile_set_name": "PubMed Abstracts"
} |
Immunoprecipitation of alpha 2a-adrenergic receptor-GTP-binding protein complexes using GTP-binding protein selective antisera. Changes in receptor/GTP-binding protein interaction following agonist binding.
The nature of the interaction of cloned alpha 2a-adrenergic receptors from LLC-PK1-O clone cells with G proteins ... | {
"pile_set_name": "PubMed Abstracts"
} |
Discordant recovery of bone mass and mechanical properties during prolonged recovery from disuse.
Profound bone loss at weight bearing sites is a primary effect of long-duration spaceflight. Moreover, a significant increase in estimated fracture risk remains even 1 year after returning to Earth; hence, it is important ... | {
"pile_set_name": "PubMed Abstracts"
} |
Kinetic studies on endo-beta-galactosidase by a novel colorimetric assay and synthesis of N-acetyllactosamine-repeating oligosaccharide beta-glycosides using its transglycosylation activity.
Novel chromogenic substrates for endo-beta-galactosidase were designed on the basis of the structural features of keratan sulfate... | {
"pile_set_name": "PubMed Abstracts"
} |
Reductive approach to mixed valency (n = 1-) in the pyrazine ligand-bridged [(acac)2Ru(μ-L(2-))Ru(acac)2](n) (L(2-) = 2,5-pyrazine-dicarboxylate) through experiment and theory.
The diruthenium(III) complex [(acac)(2)Ru(μ-L(2-))Ru(acac)(2)] (1) with acac(-) = acetylacetonato = 2,4-pentanedionato and a 2,5-pyrazine-dicar... | {
"pile_set_name": "PubMed Abstracts"
} |
Anti-AB titer changes in patients with ABO incompatibility after living related kidney transplantations: survey of 101 cases to determine whether splenectomies are necessary for successful transplantation.
A shortage of organ donors for transplantation has become a serious problem throughout the world. To overcome this... | {
"pile_set_name": "PubMed Abstracts"
} |
Activation of 5-HT3 receptors enhances the electrically evoked release of [3H]noradrenaline in rat brain limbic structures.
The ability of 5-HT receptor agonists to modulate the electrically evoked release of [3H]noradrenaline was tested on preloaded slices of the rat brain. The 5-HT3 receptor agonist 2-methyl-5-hydrox... | {
"pile_set_name": "PubMed Abstracts"
} |
Phalangeal quantitative ultrasound technology and dual energy X-ray densitometry in patients with primary hyperparathyroidism: influence of sex and menopausal status.
Fifty-one patients with surgically proven primary hyperparathyroidism (PHPT), 11 males and 40 females, mean age+/-SD: 55.9+/-14.1 years, and 58 age- and ... | {
"pile_set_name": "PubMed Abstracts"
} |
Health-promoting effects of Lactobacillus-fermented barley in weaned pigs challenged with Escherichia coli K88.
Fermented feeds are being considered as practical alternatives to antimicrobial growth promoters (AGP) supplemented in nursery pig diets. This study aimed to investigate health-promoting effects of fermented ... | {
"pile_set_name": "PubMed Abstracts"
} |
Insulin like growth factor binding protein-7 reduces growth of human breast cancer cells and xenografted tumors.
Previously, we have shown that insulin-like growth factor binding protein-7 (IGFBP-7) expression is inversely correlated with disease progression in breast cancer and is associated with poor outcome. To furt... | {
"pile_set_name": "PubMed Abstracts"
} |
Systematic evaluation of tumoral 99mTc-MAA uptake using SPECT and SPECT/CT in 502 patients before 90Y radioembolization.
The aim of this study was to evaluate the (99m)Tc-macroaggregated albumin ((99m)Tc-MAA) uptake of primary and secondary liver tumors in a large patient cohort before (90)Y radioembolization. We inclu... | {
"pile_set_name": "PubMed Abstracts"
} |
Development of hypertension in a pyelonephritis-induced model: the effect of salt intake and inability of renal sodium handling.
The role of the kidney in the control of blood pressure has been convincingly demonstrated by several studies. Recent evidence has suggested that subtle acquired tubulointerstitial injury may... | {
"pile_set_name": "PubMed Abstracts"
} |
Mutant 5-hydroxytryptamine 1A receptor D116A is a receptor activated solely by synthetic ligands with a rich pharmacology.
Like other biogenic amine G protein-coupled receptors, mutation of the conserved aspartatic residue into alanine at position 116 (D116A(3.32)) in the 5-hydroxytryptamine (5-HT)(1A) receptor greatly... | {
"pile_set_name": "PubMed Abstracts"
} |
Intestinal absorption, blood transport and hepatic and muscle metabolism of fatty acids in preruminant and ruminant animals.
Current research on lipid metabolism in ruminants aims to improve the growth and health of the animals and the muscle characteristics associated with meat quality. This review, therefore, focuses... | {
"pile_set_name": "PubMed Abstracts"
} |
The influence of RN genotype, including the new V199I allele, on the eating quality of pork loin.
The eating quality of M. longissimus dorsi (LD) from RN(-) homozygotes, RN(-) heterozygotes and RN(-) non-carriers was investigated in a Swedish Hampshire×Finnish Landrace pig population. The recently identified new allele... | {
"pile_set_name": "PubMed Abstracts"
} |
Psoriatic arthritis: a retrospective study of 162 patients.
The aim of our study was to determine the prevalence of psoriatic arthritis in the patients with psoriasis and to analyze retrospectively the results of a 34-year multidisciplinary management of the patients with psoriatic arthritis. The study included 162 out... | {
"pile_set_name": "PubMed Abstracts"
} |
Intracellular pH regulation and buffer capacity in CO2/HCO3-buffered media in cultured epithelial cells from rainbow trout gills.
The influence of a CO2/HCO3(-)-buffered medium on intracellular pH regulation of gill pavement cells from freshwater rainbow trout was examined in monolayers grown in primary culture on glas... | {
"pile_set_name": "PubMed Abstracts"
} |
Plasticity in the synthesis and storage of substance P and calcitonin gene-related peptide in primary afferent neurons during peripheral inflammation.
Several indices of peptidergic, primary afferent neural transmission in rat at the level of the lumbar spinal cord exhibited differential changes over time in response t... | {
"pile_set_name": "PubMed Abstracts"
} |
The claudin-16 channel gene is transcriptionally inhibited by 1,25-dihydroxyvitamin D.
What is the central question of this study? In the kidney, the bulk of the filtered Mg(2+) is reabsorbed in the thick ascending limb by paracellular conductance, mediated by the tight junction protein, claudin-16, which is encoded by... | {
"pile_set_name": "PubMed Abstracts"
} |
Development of the non-palindromic adaptor polymerase chain reaction (NPA-PCR) for the amplification of alpha- and beta-chain T-cell receptor cDNAs.
We have developed a highly efficient new method for the amplification of alpha- and beta-chain human T-cell receptor (TCR) cDNAs. This method is designated non-palindromic... | {
"pile_set_name": "PubMed Abstracts"
} |
Xenon(IV)-carbon bond of [C6F5XeF2]+; structural characterization and bonding of [C6F5XeF2][BF4], [C6F5XeF2][BF4]·2HF, and [C6F5XeF2][BF4]·nNCCH3 (n = 1, 2); and the fluorinating properties of [C6F5XeF2][BF4].
The [C6F5XeF2](+) cation is the only example of a Xe(IV)-C bond, which had only been previously characterized ... | {
"pile_set_name": "PubMed Abstracts"
} |
Parathyroid hormone deficiency and excess: similar effects on trabecular bone but differing effects on cortical bone.
Parathyroid hormone (PTH) may be anabolic at trabecular bone and catabolic in cortical bone. As many regions of the skeleton contain both types of bone, the effects of PTH deficiency or excess may be di... | {
"pile_set_name": "PubMed Abstracts"
} |
An unusual organoyttrium alkyl complex containing a [C5HMe3(η(3)-CH2)-C5H4N-κ]- ligand and an elusive cyclopentadienide-based scandium tuck-over zwitterion obtained by C-H bond activation.
The acid-base reaction between Y(CH(2)SiMe(3))(3)(thf)(2) and the pyridyl-functionalized cyclopentadienyl (Cp) ligand C(5)Me(4)H-C(... | {
"pile_set_name": "PubMed Abstracts"
} |
Bolus application of landiolol and esmolol: comparison of the pharmacokinetic and pharmacodynamic profiles in a healthy Caucasian group.
The aim of this prospective study was to compare in non-Asian subjects the pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability of two short-acting cardioselective β... | {
"pile_set_name": "PubMed Abstracts"
} |
[The role of signal transduction systems in the regulation of the production and secretion of hCG (alpha, beta) by cultured human choriocarcinoma cells (BeWo)].
The BeWo cell line, derived from choriocarcinoma, produces and releases human chorionic gonadotropin (hCG) and its alpha- and beta-subunits. The authors have a... | {
"pile_set_name": "PubMed Abstracts"
} |
[Effects and related mechanism of retinoid X receptor agonist bexarotene on atherosclerosis progression in diabetic apoE(-/-) mice].
To explore the effect of retinoid X receptor (RXR) agonist bexarotene on atherosclerosis and the potential mechanism in streptozotocin (STZ) induced diabetic apolipoprotein E knockout (ap... | {
"pile_set_name": "PubMed Abstracts"
} |
Mono- and dinuclear cobalt complexes with chelating or bridging bidentate P,N phosphino- and phosphinito-oxazoline ligands: synthesis, structures and catalytic ethylene oligomerisation.
Cobalt(ii) complexes of the type [CoCl(2)(P,N)], where P,N represents a heterobidentate phosphino- or phosphinito-oxazoline-type ligan... | {
"pile_set_name": "PubMed Abstracts"
} |
Maternal overnutrition enhances mRNA expression of adipogenic markers and collagen deposition in skeletal muscle of beef cattle fetuses.
Twenty-four pregnant Nellore cows were randomly assigned into 2 feeding level groups (control [CTL]; fed 1.0 times the maintenance requirement; n = 12; and overnourished [ON]; fed at ... | {
"pile_set_name": "PubMed Abstracts"
} |
[Anatomo-clinical study of arterioventricular disorders].
The relationship of the great arteries with their respective ventricles in the three toncoconal morphologies depends on the orientation and rotation of the septum of the trunk and cone. In this work we study a case of crossed great arteries and another of partia... | {
"pile_set_name": "PubMed Abstracts"
} |
[Epidemiological characteristics of waist circumference and abdominal obesity among Chinese adults in 2010-2012].
Objective: To investigate the epidemiological characteristics of waist circumference (WC) and abdominal obesity (AO) among Chinese adults aged 18 and above. Methods: Data were collected from China National ... | {
"pile_set_name": "PubMed Abstracts"
} |
Receptor-mediated stimulatory effect of atrial natriuretic factor, brain natriuretic peptide, and C-type natriuretic peptide on testosterone production in purified mouse Leydig cells: activation of cholesterol side-chain cleavage enzyme.
We have investigated the mechanism by which different natriuretic peptides stimula... | {
"pile_set_name": "PubMed Abstracts"
} |
Sasanquasaponin ΙΙΙ from Schima crenata Korth induces autophagy through Akt/mTOR/p70S6K pathway and promotes apoptosis in human melanoma A375 cells.
Melanoma is a high fatality skin cancer which lacks effective drugs. Sasanquasaponin, an important sort of constituents in theaceae, has been demonstrated to have potent a... | {
"pile_set_name": "PubMed Abstracts"
} |
Effect of physical training on lipids, lipoproteins, apolipoproteins, lipases, and endogenous sex hormones in men with premature myocardial infarction.
In 17 men, aged 27 to 54 years, with myocardial infarction 2 to 10 months before the current exercise study, we aimed to determine whether 3 months of exercise training... | {
"pile_set_name": "PubMed Abstracts"
} |
Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives.
The methods of theoretical chemistry have been used to elucidate the molecular properties of the substituted imidazoline and oxazoline structures, a class of potent agonists and... | {
"pile_set_name": "PubMed Abstracts"
} |
The novel effects of 3,5,3'-triiodo-L-thyronine on myocyte contractile function and beta-adrenergic responsiveness in dilated cardiomyopathy.
Medical management of patients with chronic left ventricular dysfunction continues to be a difficult problem. Recent clinical and experimental studies have suggested that 3,5,3'-... | {
"pile_set_name": "PubMed Abstracts"
} |
Biomechanical evaluation of destabilization following minimally invasive decompression for lumbar spinal canal stenosis.
This study aimed to clarify changes in segmental instability following a unilateral approach for microendoscopic posterior decompression and muscle-preserving interlaminar decompression compared with... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of p38 mitogen-activated protein kinase on osteogenic differentiation of human periodontal ligament stem cells in inflammatory microenvironment.
To investigate the expression of mitogen-activated protein kinase (MAPK) in the chronic periodontitis tissue-derived in the periodontal ligament stem cells (PDLSCs) an... | {
"pile_set_name": "PubMed Abstracts"
} |
Maternal plasma and amniotic fluid angiogenic factors and their receptors in monochorionic twin pregnancies complicated by twin-to-twin transfusion syndrome.
Angiogenic factors play a role in human placentation and may be aberrant in severe twin-to-twin transfusion syndrome (TTTS). The aim of this study was to investig... | {
"pile_set_name": "PubMed Abstracts"
} |
Finite basis representations with nondirect product basis functions having structure similar to that of spherical harmonics.
The currently most efficient finite basis representation (FBR) method [Corey et al., in Numerical Grid Methods and Their Applications to Schrodinger Equation, NATO ASI Series C, edited by C. Cerj... | {
"pile_set_name": "PubMed Abstracts"
} |
Detection of the environmental antiandrogen p,p-DDE in CD and long-evans rats using a tier I screening battery and a Hershberger assay.
In this report, p,p'-DDE, a weak androgen receptor (AR) antagonist, has been examined in a Tier I screening battery designed to detect endocrine-active compounds (EACs). The screening ... | {
"pile_set_name": "PubMed Abstracts"
} |
[Susceptibilities of bacteria isolated from patients with respiratory infectious diseases to antibiotics (1993)].
Bacteria isolated from respiratory tract infections were collected in cooperation with institutions located throughout Japan, since 1981, and the Ikemotor et al. have been investigating susceptibilities of ... | {
"pile_set_name": "PubMed Abstracts"
} |
Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs).
The effect on cytotoxicity of combining a range of clinically important non-steroidal anti-inflammatory drugs (NSAIDs) with a variety of chemotherapeutic drugs was examined in the ... | {
"pile_set_name": "PubMed Abstracts"
} |
How effective are current therapies for acromegaly?
Currently available therapies for acromegaly are transsphenoidal surgery (TSS), radiotherapy (RT) and medical therapy with the dopamine agonists and somatostatin analogues. The goals of these therapies for acromegaly are to normalize excessive hormone secretion, thus ... | {
"pile_set_name": "PubMed Abstracts"
} |
Activated alpha 2-macroglobulin promotes mitogenesis in rat vascular smooth muscle cells by a mechanism that is independent of growth-factor-carrier activity.
Vascular smooth muscle cell (vSMC) proliferation is important in atherosclerosis. We previously demonstrated that methylamine-activated alpha 2-macroglobulin (al... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of changing the essential and functional fatty acid intake of dairy calves.
There is limited information on the effects and requirements of specific fatty acids for dairy calves. The starter diet based on corn and soybean meal, which is typical in the United States, is low in C(18:3), and the ratio of C(18:2) t... | {
"pile_set_name": "PubMed Abstracts"
} |
Immunohistochemical identification of discrete subsets of rat olfactory neurons and the glomeruli that they innervate.
Glomeruli at the posterior margin of the main olfactory bulb differ in several respects from those located in the remainder of the bulb; e.g., the olfactory sensory neurons (OSNs) that project here exh... | {
"pile_set_name": "PubMed Abstracts"
} |
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