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Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity.
Repeated daily cocaine injections have been shown to alter mu-opioid receptor densities in the caudate putamen and nucleus accumbens of rat brain (Unterwald et al., 1991, 1992). Adenylyl cyclase activity was measured in... | {
"pile_set_name": "PubMed Abstracts"
} |
Stereospecific formation of dinuclear vanadium(V) tartrato complexes.
The first dinuclear nonperoxido tartrato complexes of vanadium(V), (NMe(4))(2)[V(2)O(4)((2R,3R)-H(2)tart)(2)] x 6 H(2)O (1), (NMe(4))(2)[V(2)O(2)((2R,3R)-tart)((2S,3S)-tart)] (2), (NEt(4))(2)[V(2)O(2)((2R,3R)-tart)((2S,3S)-tart)] (3) (tart = tartrato... | {
"pile_set_name": "PubMed Abstracts"
} |
[Significance of multiple analysis of platelet Ca2+ mobilization by using some available methods measuring cytosolic Ca2+ concentration, membrane-bound Ca2+ and Ca2+ flux across the plasma membrane].
Intracellular Ca2+ mobilization in the resting platelets undergoing Ca2+ influx and in the activated platelets stimulate... | {
"pile_set_name": "PubMed Abstracts"
} |
[The role of signal transduction systems in the regulation of the production and secretion of hCG (alpha, beta) by cultured human choriocarcinoma cells (BeWo)].
The BeWo cell line, derived from choriocarcinoma, produces and releases human chorionic gonadotropin (hCG) and its alpha- and beta-subunits. The authors have a... | {
"pile_set_name": "PubMed Abstracts"
} |
[Pulsatility index and resistance index in the aortic bifurcation area of growth retarded fetuses].
To specify diagnostic importance of fetoplacental flow parameters PI, RI during pregnancy complicated by ultrasonografically detected intrauterine growth retardation-IUGR. Dpt. of Obstetric and Gynaecology, Safarik's Uni... | {
"pile_set_name": "PubMed Abstracts"
} |
Comparison of the mutations at Hprt exon 3 of T-lymphocytes from B6C3F1 mice and F344 rats exposed by inhalation to 1,3-butadiene or the racemic mixture of 1,2:3,4-diepoxybutane.
Experiments were conducted to define the spectra of mutations occurring in Hprt exon 3 of T-cells isolated from spleens of female B6C3F1 mice... | {
"pile_set_name": "PubMed Abstracts"
} |
Template syntheses of copper(II) complexes from arylhydrazones of malononitrile and their catalytic activity towards alcohol oxidations and the nitroaldol reaction: hydrogen bond-assisted ligand liberation and E/Z isomerisation.
A one-pot template condensation of 2-(2-(dicyanomethylene)hydrazinyl)benzenesulfonic acid (... | {
"pile_set_name": "PubMed Abstracts"
} |
Correlation Between 18F-FDG PET/CT Findings and BI-RADS Assessment Using Ultrasound in the Evaluation of Breast Lesions: A Multicenter Study.
To analyze the correlation between ultrasound breast imaging reporting and data system (BI-RADS) category and fluorodeoxyglucose [18F] (18F-FDG) positron emission tomography/comp... | {
"pile_set_name": "PubMed Abstracts"
} |
Relationship between actions of transforming growth factor (TGF)-beta and cell surface expression of its receptors in clonal osteoblastic cells.
Various osteoblastic cell lines were examined for the relationship between the presence of cell-surface transforming growth factor (TGF)-beta receptors and the synthesis of ma... | {
"pile_set_name": "PubMed Abstracts"
} |
Liver X receptor agonist methyl-3β-hydroxy-5α,6α-epoxycholanate attenuates atherosclerosis in apolipoprotein E knockout mice without increasing plasma triglyceride.
Liver X receptors (LXRs) promote macrophage reverse cholesterol transport and cholesterol excretion from the body. The synthetic LXR ligands T0901317 and G... | {
"pile_set_name": "PubMed Abstracts"
} |
Coordination and Coupling of OH-Functionalized C2 Units at a Single Metal Center: The Synthesis of Alkynyl(Vinylidene), Alkynyl(Enyne), Bis(Alkynyl)Hydrido, Enynyl, and Hexapentaene Rhodium Complexes from Propargylic Alcohols as Precursors.
The reaction of [Rh(η3 -C3 H5 )-(PiPr3 )2 ] (1) with HCCCH(Ph)OH yields the a... | {
"pile_set_name": "PubMed Abstracts"
} |
Comparison of follicular fluid amphiregulin and EGF concentrations in patients undergoing IVF with different stimulation protocols.
Epidermal growth factor (EGF)-like growth factors, such as amphiregulin (AR) and EGF, have emerged as mediators to propagate Luteinizing hormone (LH) stimulus for the oocyte maturation thr... | {
"pile_set_name": "PubMed Abstracts"
} |
Effect of limit feeding high- and low-concentrate diets with Saccharomyces cerevisiae on digestibility and on dairy heifer growth and first-lactation performance.
Growth and digestibility were examined for heifers limit fed high- (HC; 60%) and low-concentrate (LC; 20%) diets with or without yeast culture (YC) addition ... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of cabbage leaves compared to gel packs for mothers with breast engorgement: Randomised controlled trial.
The effects of cold cabbage leaves and cold gel packs on breast engorgement management have been inconclusive. No studies have compared the effects of these methods on breast engorgement using a rigorou... | {
"pile_set_name": "PubMed Abstracts"
} |
[Comparative analysis between origin of cooked traditional Chinese medicine powder and modern formula granules].
In this study, the origin and causes of cooked traditional Chinese medicine powder were reviewed, and a comprehensive analysis was made for the time background of modern traditional Chinese medicine formula ... | {
"pile_set_name": "PubMed Abstracts"
} |
[Effect of vitamin D supplementation and outdoor time on the 25(OH)D level in adolescents].
To assess the effect of vitamin D( VD) supplementation and outdoor time intervention on the 25( OH) D level in adolescents. In April2015, participants from three classes in a college of North Anhui were randomly assigned to VD s... | {
"pile_set_name": "PubMed Abstracts"
} |
Contribution of expiratory muscle pressure to dynamic intrinsic positive end-expiratory pressure: validation using the Campbell diagram.
In spontaneously breathing (SB) patients expiratory muscle contraction leads to an overestimation of dynamic intrinsic PEEP (PEEP(i),dyn). To quantify this overestimation, PEEP(i),dyn... | {
"pile_set_name": "PubMed Abstracts"
} |
mer, fac, and Bidentate Coordination of an Alkyl-POP Ligand in the Chemistry of Nonclassical Osmium Hydrides.
Nonclassical and classical osmium polyhydrides containing the diphosphine 9,9-dimethyl-4,5-bis(diisopropylphosphino)xanthene (xant(PiPr2)2), coordinated in κ3-mer, κ3-fac, and κ2-P,P fashions, have been isolate... | {
"pile_set_name": "PubMed Abstracts"
} |
Effect of supplementation of dried distillers grains with solubles on forage intake and characteristics of digestion of beef heifers grazing small-grain pasture.
Sixteen ruminally cannulated, English-crossbred heifers (378 ± 28.4 kg) grazing small-grain pasture (SGP) were used in a completely randomized design to evalu... | {
"pile_set_name": "PubMed Abstracts"
} |
[Wnt5a modulates vincristine resistance through PI3K/Akt/GSK3β signaling pathway in human ovarian carcinoma SKOV3/VCR cells].
The aim of this study was to investigate the effect of Wnt5a on the vincristine (VCR) resistance in human ovarian carcinoma SKOV3 cells and its possible mechanism. The drug-resistant SKOV3/VCR c... | {
"pile_set_name": "PubMed Abstracts"
} |
H-magnetic resonance spectroscopy of retrobulbar tissue in Graves ophthalmopathy.
Accumulation of glycosaminoglycans in the orbit may play an important role in the development of Graves ophthalmopathy. Therefore, it might be clinically useful to evaluate the concentration of glycosaminoglycans in the orbit in patients ... | {
"pile_set_name": "PubMed Abstracts"
} |
L-Tyr-Induced Phosphorylation of Tyrosine Hydroxylase at Ser40: An Alternative Route for Dopamine Synthesis and Modulation of Na+/K+-ATPase in Kidney Cells.
Dopamine (DA) is a natriuretic hormone that inhibits renal sodium reabsorption, being Angiotensin II (Ang II) its powerful counterpart. These two systems work toge... | {
"pile_set_name": "PubMed Abstracts"
} |
Increased neuronal and glial expression of protein kinase C isoforms in neocortex of transgenic Tg2576 mice with amyloid pathology.
We investigated the influence of five- to sevenfold neuronal overexpression of the Swedish mutation of human APP695 (APPsw) in the transgenic mouse strain Tg2576 on neocortical protein kin... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of MDR1 1236C > T-2677G > T-3435C > T polymorphisms on the intracellular accumulation of tacrolimus, cyclosporine A, sirolimus and everolimus.
1. Overexpression of P-glycoprotein (P-gp, encoded by MDR1) mediates resistance to multiple immunosuppressors. Several common MDR1 variants (1236C > T, 2677G > T, 3435C ... | {
"pile_set_name": "PubMed Abstracts"
} |
Bioequivalence evaluation of a folate-supplemented oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium versus ethinylestradiol/drospirenone and levomefolate calcium alone.
Neural tube defects (NTDs) are congenital malformations that occur during early embryonic development. Suboptimal mater... | {
"pile_set_name": "PubMed Abstracts"
} |
Low temperature synthesis, structural and dosimetric characterization of ZnAl2O4:Ce3+ nanophosphor.
Dosimetric properties of γ-irradiated ZnAl2O4:Ce(3+) (1-9 mol%) nanophosphors were studied and reported for the first time. The phosphor prepared by solution combustion route was well characterized by powder X-ray diffra... | {
"pile_set_name": "PubMed Abstracts"
} |
Retrograde axonal transport after radioactive hydroxyindole injections into the olfactory bulb-an autoradiographic study.
Light microscope autoradiography was used to study the retrograde transport of labelled material after injection of [(3)H]serotonin ([(3)H]5-HT), [(3)H]5-hydroxytryptophan ([(3)H]5-HTP) and [(14)C]5... | {
"pile_set_name": "PubMed Abstracts"
} |
Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor.
Multipin peptide synthesis has been employed to produce biotinylated 11-mer phosphopeptides tha... | {
"pile_set_name": "PubMed Abstracts"
} |
Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter.
The role of ERK and Jun N-terminal kinase (JNK) in basal- and GnRH-stimulated LHbeta-promoter activity was examined in the gonadotroph cell line Lbet... | {
"pile_set_name": "PubMed Abstracts"
} |
Common and distinct factors regulate expression of mRNA for ETV5 and GDNF, Sertoli cell proteins essential for spermatogonial stem cell maintenance.
Ets variant gene 5 (ETV5) and glial cell-derived neurotrophic factor (GDNF) are produced in Sertoli cells and required for maintenance and self-renewal of spermatogonial s... | {
"pile_set_name": "PubMed Abstracts"
} |
Glucose-6-phosphate dehydrogenase and leptin are related to marbling differences among Limousin and Angus or Japanese Black x Angus steers.
This work investigated the metabolic basis for the variability of carcass and i.m. adiposity in cattle. Our hypothesis was that the comparison of extreme breeds for adiposity might... | {
"pile_set_name": "PubMed Abstracts"
} |
Control of insulin-like growth factor binding protein-5 protease synthesis and secretion by human fibroblasts and porcine aortic smooth muscle cells.
IGF binding protein-5 (IGFBP-5) is an important trophic factor for controlling the actions of IGF-I in human dermal fibroblasts and porcine aortic smooth muscle cells. Wh... | {
"pile_set_name": "PubMed Abstracts"
} |
Purification by affinity chromatography of 2,4-dienoyl-CoA reductases from bovine liver and Escherichia coli.
1. Dye-ligand chromatography using immobilized Cibacron blue F3GA (blue Sepharose CL-6B) and Procion red HE3B (Matrex gel red A) as matrices and general ligand chromatography employing immobilized 2',5'-ADP (2'... | {
"pile_set_name": "PubMed Abstracts"
} |
Warning thresholds on the basis of origin of amplitude changes in transcranial electrical motor-evoked potential monitoring for cervical compression myelopathy.
A retrospective analysis of prospectively collected data from consecutive patients undergoing transcranial electrical motor-evoked potential (TCE-MEP: compound... | {
"pile_set_name": "PubMed Abstracts"
} |
Retinoblastoma (Rb) tumor-suppressor pathway alterations in meningeal hemangiopericytomas: High E2F transcription factor 1 expression and loss of Rb expression: study by double immunofluorescence staining and laser-scanning confocal microscopy.
The authors analyzed the retinoblastoma (Rb) tumor-suppressor pathway in me... | {
"pile_set_name": "PubMed Abstracts"
} |
CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.
Induction of CYP2E1 (cytochrome P450 2E1) by ethanol appears to be one of the central pathways by which ethanol generates a state of oxidative stress. CYP2E1 is a loosely coupled enzyme... | {
"pile_set_name": "PubMed Abstracts"
} |
[Effects of As2O3 on tissue factor, plasminogen activator inhibitor-1 and -2 expression in NB4, HL-60 and THP-1 cells].
To explore the effects of arsenic trioxide (As2O3) on tissue factor (TF), plasminogen activator inhibitor-1(PAI-I) and PAI-2 expression in NB4, HL-60 and THP-1 cells. Inhibition of the cell proliferat... | {
"pile_set_name": "PubMed Abstracts"
} |
Investigation of gene expressions related to cholesterol metabolism in rats fed diets enriched in n-6 or n-3 fatty acid with a cholesterol after long-term feeding using quantitative-competitive RT-PCR analysis.
We have developed a method to quantitate hepatic apolipoprotein (apo) B, LDL receptor, 3-hydroxy-3-methylglut... | {
"pile_set_name": "PubMed Abstracts"
} |
Spectroscopic, Electrochemical and Computational Characterisation of Ru Species Involved in Catalytic Water Oxidation: Evidence for a [Ru(V) (O)(Py2 (Me) tacn)] Intermediate.
A new family of ruthenium complexes based on the N-pentadentate ligand Py2 (Me) tacn (N-methyl-N',N''-bis(2-picolyl)-1,4,7-triazacyclononane) has... | {
"pile_set_name": "PubMed Abstracts"
} |
Direct fusion of subunits of heterodimeric nitric oxide sensitive guanylyl cyclase leads to functional enzymes with preserved biochemical properties: evidence for isoform specific activation by ciguates.
Nitric oxide sensitive guanylyl cyclase (NOsGC) is a heterodimeric enzyme consisting of an α and a β subunit. Two he... | {
"pile_set_name": "PubMed Abstracts"
} |
Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative atrophic glossitis patients.
Approximately 27% of atrophic glossitis (AG) patients have the serum gastric parietal cell antibody (GPCA) positivity. This study assessed whether the serum GPCA or AG itself wa... | {
"pile_set_name": "PubMed Abstracts"
} |
Sodium butyrate-mediated induction of the glycoprotein hormone alpha-subunit gene: requirement for continued protein synthesis, identification of a butyrate-responsive element, and inhibition of promoter activation by 2-deoxyglucose.
Production of the glycoprotein hormone alpha-subunit (GPH alpha) was enhanced by sodiu... | {
"pile_set_name": "PubMed Abstracts"
} |
Repeated ruminal acidosis challenges in lactating dairy cows at high and low risk for developing acidosis: feeding, ruminating, and lying behavior.
An experiment was conducted to determine whether the susceptibility to ruminal acidosis, as defined through differences in days in milk (DIM), milk production level, and ra... | {
"pile_set_name": "PubMed Abstracts"
} |
Predictors of first repeat biopsy cancer detection with suspected local stage prostate cancer.
We determine demographic and tumor related predictors of repeat biopsy cancer detection in men with suspected stage T1c-2 prostate cancer. The study population included 298 consecutive men with suspected stage T1c-2 prostate ... | {
"pile_set_name": "PubMed Abstracts"
} |
Cyclic AMP negatively controls c-myc transcription and G1 cell cycle progression in p210 BCR-ABL transformed cells: inhibitory activity exerted through cyclin D1 and cdk4.
Raised intracellular cyclic AMP (cAMP) has been demonstrated to exert an antiproliferative effect in myeloid cells. How the antiproliferative activi... | {
"pile_set_name": "PubMed Abstracts"
} |
[Establishment of enzalutamide-resistant human prostate cancer cell lines and screening of lncRNA and mRNA expression profiles].
To establish enzalutamide-resistant human prostate cancer cell lines and screen out the lncRNA and mRNA expression profiles associated with enzalutamide resistance. Human prostate cancer cell... | {
"pile_set_name": "PubMed Abstracts"
} |
Chinese phytotherapy to reduce stress, anxiety and improve quality of life: randomized controlled trial.
To evaluate the effect of Chinese phytotherapyto reduce stress levels, anxiety and improve quality of life. double-blind randomized controlled trial with 89 volunteers divided into three groups: control (no interven... | {
"pile_set_name": "PubMed Abstracts"
} |
[Features of immune proteasome expression in the development of rat central nervous system].
Formation of the central nervous system in ontogeny and function in adult mammals are controlled by universal ubiquitin-proteasome proteolytic system. The aim of this work was to study the dynamics of expression of immune prote... | {
"pile_set_name": "PubMed Abstracts"
} |
Increased intracellular pH is not necessary for ribosomal protein s6 phosphorylation, increased protein synthesis, or germinal vesicle breakdown in Xenopus oocytes.
An increase in intracellular pH (pHi) and ribosomal protein S6 phosphorylation during Xenopus oocyte maturation has been reported by several laboratories. ... | {
"pile_set_name": "PubMed Abstracts"
} |
Examination of the persistency of milk fatty acid composition responses to fish oil and sunflower oil in the diet of dairy cows.
Based on the potential benefits of cis-9, trans-11 conjugated linoleic acid (CLA) for human health, there is a need to develop effective strategies for enhancing milk fat CLA concentrations. ... | {
"pile_set_name": "PubMed Abstracts"
} |
An expression of IGF-binding proteins in normal and pre-eclamptic human umbilical cord serum and tissues.
Pre-eclampsia, is the most common, pregnancy-associated pathological syndrome accompanied by a significant increase in collagen and sulphated glycosaminoglycans (GAGs) contents in the umbilical cord arteries (UCAs)... | {
"pile_set_name": "PubMed Abstracts"
} |
Comparison of T1-weighted fast spin-echo and T1-weighted fluid-attenuated inversion recovery images of the lumbar spine at 3.0 Tesla.
T1-weighted fluid-attenuated inversion recovery (FLAIR) sequence has been reported to provide improved contrast between lesions and normal anatomical structures compared to T1-weighted f... | {
"pile_set_name": "PubMed Abstracts"
} |
Influence of energy source on forage intake, digestibility, in situ forage degradation, and ruminal fermentation in beef steers fed medium-quality brome hay.
Eight ruminally cannulated steers (average initial weight 196 +/- 13 kg) were arranged in a replicated 4 x 4 Latin square. Steers had ad libitum access to chopped... | {
"pile_set_name": "PubMed Abstracts"
} |
[Effect of Berberine on the Insulin Resistance and TLR4/IKKbeta/NF-kappaB Signaling Pathways in Skeletal Muscle of Obese Rats with Insulin Resistance].
To explore the possible mechanism of berberine improve insulin resistance in skeletal muscle of obese rats. Forty Wistar rats were divided into normal control group (NC... | {
"pile_set_name": "PubMed Abstracts"
} |
External Validation of the International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury: Prognostic Models for Traumatic Brain Injury on the Study of the Neuroprotective Activity of Progesterone in Severe Traumatic Brain Injuries Trial.
Prediction models for patients with traumatic brai... | {
"pile_set_name": "PubMed Abstracts"
} |
Hydrolysis and isomerization of trans,trans-farnesyl diphosphate by Andrographis tissue-culture enzymes.
Incubation of (3R,5S)-[5-3H1]mevalonate + (3RS)-[2-14C]mevalonate with Andrographis cell-free extract leads to trans,trans-farnesol and cis,trans-farnesol which both totally retain tritium. 2. This conflicts with ou... | {
"pile_set_name": "PubMed Abstracts"
} |
Protein kinase C can inhibit TRPC3 channels indirectly via stimulating protein kinase G.
There are two known phosphorylation-mediated inactivation mechanisms for TRPC3 channels. Protein kinase G (PKG) inactivates TRPC3 by direct phosphorylation on Thr-11 and Ser-263 of the TRPC3 proteins, and protein kinase C (PKC) ina... | {
"pile_set_name": "PubMed Abstracts"
} |
Nitric oxide mimics transcriptional and post-translational regulation during α-tocopherol cytoprotection against glycochenodeoxycholate-induced cell death in hepatocytes.
Reactive oxygen species (ROS) and nitric oxide (NO) exert a relevant role during bile acid-induced hepatotoxicity. Whether α-Tocopherol regulates oxi... | {
"pile_set_name": "PubMed Abstracts"
} |
TPP-dendrimer nanocarriers for siRNA delivery to the pulmonary epithelium and their dry powder and metered-dose inhaler formulations.
The regulation of genes utilizing the RNA interference (RNAi) mechanism via the delivery of synthetic siRNA has great potential in the treatment of a variety of lung diseases. However, t... | {
"pile_set_name": "PubMed Abstracts"
} |
DNA-PKcs deficiency sensitizes the human hepatoma HepG2 cells to cisplatin and 5-fluorouracil through suppression of the PI3K/Akt/NF-κB pathway.
The aim of the present study was to investigate the effects of DNA-PKcs deficiency on the chemosensitivity of human hepatoma HepG2 cells to cisplatin (CDDP) and 5-fluorouracil... | {
"pile_set_name": "PubMed Abstracts"
} |
Carboxyl residues in the active site of human phenol sulfotransferase (SULT1A1).
The carboxyl-specific amino acid modification reagent, Woodward's reagent K (WK), was utilized to characterize carboxyl residues (Asp and Glu) in the active site of human phenol sulfotransferase (SULT1A1). SULT1A1 was purified using the pM... | {
"pile_set_name": "PubMed Abstracts"
} |
Developmental changes in antioxidant enzymatic defences against oxidative stress in sheep placentomes.
Early pregnancy is susceptible to oxidative stress, and thus characterisation of antioxidant systems and pro- and anti-apoptotic pathways would improve understanding of placental development and function. We aimed, th... | {
"pile_set_name": "PubMed Abstracts"
} |
[Regulatory role of hypoxia inducible factor-1 alpha in the changes of contraction of vascular smooth muscle cell induced by hypoxia].
To observe the regulatory role and mechanism of hypoxia inducible factor-1 alpha (HIF-1 alpha) in the contractile changes of vascular smooth muscle cell (VSMC) induced by hypoxia. Cells... | {
"pile_set_name": "PubMed Abstracts"
} |
Comparison of diagnostic accuracy of aspartate aminotransferase to platelet ratio index and fibrosis-4 index for detecting liver fibrosis in adult patients with chronic hepatitis B virus infection: a systemic review and meta-analysis.
The aspartate aminotransferase-to-platelet ratio index (APRI) and fibrosis index base... | {
"pile_set_name": "PubMed Abstracts"
} |
Correlation of tumor necrosis factor-β and interleukin-1 gene cluster polymorphism with susceptibility to bacteremia in patients undergoing kidney transplantation.
Bacteremia remains a significant cause of morbidity and mortality after kidney transplantation. This study was conducted to investigate whether the polymorp... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis, radioiodination and in vitro and in vivo sigma receptor studies of N-1-allyl-N´-4-phenethylpiperazine analogs.
Sigma-1 (σ(1)) receptor radioligands are useful for basic pharmacology studies and for imaging studies in neurology, psychiatry and oncology. We derived a hybrid structure, N-1-allyl-N´-4-phenethylp... | {
"pile_set_name": "PubMed Abstracts"
} |
Evaluation of osteocalcin and pyridinium crosslinks of bone collagen as markers of bone turnover in gingival crevicular fluid during different stages of orthodontic treatment.
Osteocalcin (Oc) and the collagen cross-links pyridinoline (Pyr) and deoxypyridinoline (dPyr) are used as markers of bone turnover in metabolic ... | {
"pile_set_name": "PubMed Abstracts"
} |
[The morphology and thickness of cornea in patients with Marfan syndrome].
To search for the characteristics of MFS in corneal morphology and thickness. Twenty-four patients (48 eyes) with MFS and 24 healthy age- and gender-matched volunteers (48 eyes) were recruited in this clinical prospective, and comparative series... | {
"pile_set_name": "PubMed Abstracts"
} |
Cyclin-dependent kinase 9 is required for tumor necrosis factor-alpha-stimulated matrix metalloproteinase-9 expression in human lung adenocarcinoma cells.
The proinflammatory cytokine tumor necrosis factor-alpha (TNF-alpha) promotes tumor progression through activation of matrix metalloproteinase (MMP) activity. MMP-9 ... | {
"pile_set_name": "PubMed Abstracts"
} |
Impact of Multicolored Asian Lady Beetles on the sensory properties of Concord and Niagara grape juice.
The presence of Multicolored Asian Lady Beetles (MALB) in grape juice is increasingly problematic. The overall objective of this study was to determine the specific sensory impacts of MALB on Concord and Niagara grap... | {
"pile_set_name": "PubMed Abstracts"
} |
[Down-regulation of Smoothened gene expression inhibits proliferation of breast cancer stem cells].
To investigate the influence of down-regulating Smoothened (SMO) gene expression through short hairpin RNA (shRNA) on the proliferation of breast cancer stem cells. Human SMO shRNA was designed, synthesized chemically, a... | {
"pile_set_name": "PubMed Abstracts"
} |
Identification and Characterization of the Nucleolar Localization Signal of Autographa californica Multiple Nucleopolyhedrovirus LEF5.
Autographa californica multiple nucleopolyhedrovirus (AcMNPV) late expression factor 5 (LEF5) is highly conserved in all sequenced baculovirus genomes and plays an important role in pro... | {
"pile_set_name": "PubMed Abstracts"
} |
Expression of IGF-1, IL-27 and IL-35 Receptors in Adjuvant Induced Rheumatoid Arthritis Model.
IGF-1 and certain other cytokines have been shown to exert inflammatory/anti-inflammatory roles in chronic joint diseases. To assess the effect of IGF-1, IL-27 and IL-35, their interaction and their receptor expression in a r... | {
"pile_set_name": "PubMed Abstracts"
} |
Computer-Generated, Three-Dimensional Spine Model From Biplanar Radiographs: A Validity Study in Idiopathic Scoliosis Curves Greater Than 50 Degrees.
Reproducibility study of SterEOS 3-dimensional (3D) software in large, idiopathic scoliosis (IS) spinal curves. To determine the accuracy and reproducibility of various 3... | {
"pile_set_name": "PubMed Abstracts"
} |
Prognostic Accuracy of the SOFA Score, SIRS Criteria, and qSOFA Score for In-Hospital Mortality Among Adults With Suspected Infection Admitted to the Intensive Care Unit.
The Sepsis-3 Criteria emphasized the value of a change of 2 or more points in the Sequential [Sepsis-related] Organ Failure Assessment (SOFA) score, ... | {
"pile_set_name": "PubMed Abstracts"
} |
Impaired vascular function in exercising anovulatory premenopausal women is associated with low bone mineral density.
In estrogen-deficient post-menopausal women, osteoporosis shares a common link with cardiovascular disease risk, including endothelial dysfunction. The current study sought to examine associations betwe... | {
"pile_set_name": "PubMed Abstracts"
} |
Immunohistochemical Cross-Reactivity Between Paracoccidioides sp. from Dolphins and Histoplasma capsulatum.
Paracoccidioidomycosis ceti is a cutaneous disease of cetaceans caused by uncultivated Paracoccidioides brasiliensis or Paracoccidioides spp. Serological cross-reactions between paracoccidioidomycosis ceti and pa... | {
"pile_set_name": "PubMed Abstracts"
} |
2-Fluoroadenosine 3':5'-monophosphate. A metabolite of 2-fluoroadenosine in mouse cytotoxic lymphocytes.
2-Fluoroadenosine (F-Ado) is a potent inhibitor of lymphocyte-mediated cytolysis studied in vitro. The inhibition of cytolysis by F-Ado was potentiated markedly by an inhibiotr (Ro 20-1724) of adenosine 3':5'-monoph... | {
"pile_set_name": "PubMed Abstracts"
} |
CD4+IL-21+T cells are correlated with regulatory T cells and IL-21 promotes regulatory T cells survival during HIV infection.
IL-21 enhances T and natural killer cells survival and antiviral functions without promoting T cell activation during HIV infection, which makes it a better adjuvant in anti-HIV immunotherapy. D... | {
"pile_set_name": "PubMed Abstracts"
} |
Comparison of succinimidyl [(125)I]iodobenzoate with iodogen iodination methods to study pharmacokinetics and ADME of biotherapeutics.
To assess the application of succinimidyl iodobenzoate (SIB) iodination method in labeling biotherapeutics to study their pharmacokinetics (PK) and biodistribution. An IgG molecule (pro... | {
"pile_set_name": "PubMed Abstracts"
} |
Induction of apoptosis and bcl-2 expression in acute lymphoblastic leukaemia and non-Hodgkin's lymphoma in children.
bcl-2 expression is associated with the expression of the multidrug resistance molecule (p-gp) and the resistance of leukaemia cells to the induction of apoptosis. The activity of p-gp is the main mechan... | {
"pile_set_name": "PubMed Abstracts"
} |
Transfer of eleven species of the genus Burkholderia to the genus Paraburkholderia and proposal of Caballeronia gen. nov. to accommodate twelve species of the genera Burkholderia and Paraburkholderia.
It has been proposed to split the genus Burkholderia into two genera according to phylogenetic clustering: (1) a genus ... | {
"pile_set_name": "PubMed Abstracts"
} |
Different circulating progesterone concentrations during synchronization of ovulation protocol did not affect ovarian follicular and pregnancy responses in seasonal anestrous buffalo cows.
Three experiments were designed to evaluate the effect of different circulating progesterone (P4) concentrations during synchroniza... | {
"pile_set_name": "PubMed Abstracts"
} |
[Effect of aberrant H3K27me3 modification in promoter regions on cAMP response element modulator α expression in CD4+ T cells from patients with systemic lupus erythematosus].
Increased cAMP response element modulator α (CREMα) in T cells plays an essential role in the pathogenesis of systemic lupus erythematosus (SLE)... | {
"pile_set_name": "PubMed Abstracts"
} |
Structural requirements for the growth factor activity of the amino-terminal domain of urokinase.
High molecular weight urokinase-type plasminogen activator (uPA) in which proteolytic activity was inactivated (diisopropyl fluorophosphate (DFP)-uPA), its amino-terminal fragment (ATF, amino acids (aa) 1-143), and fucosyl... | {
"pile_set_name": "PubMed Abstracts"
} |
[Exogenous PTEN enhances apoptosis in pancreas cancer cell line ASPC-1 induced by hypoxia].
To investigate the effect of exogenous phosphatase and tensin homologue deleted on chromosome ten (PTEN) on cell cycle, the expression of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) prot... | {
"pile_set_name": "PubMed Abstracts"
} |
L-Cysteine in vitro can restore cellular glutathione and inhibits the expression of cell adhesion molecules in G6PD-deficient monocytes.
L-Cysteine is a precursor of glutathione (GSH), a potent physiological antioxidant. Excess glucose-6-phosphate dehydrogenase (G6PD) deficiency in African Americans and low levels of L... | {
"pile_set_name": "PubMed Abstracts"
} |
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