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Appropriately spaced nuclear localizing signals are necessary for efficient nuclear import of nonnuclear proteins.
To deliver nonnuclear proteins into the nucleus, we have examined the locations and number of nuclear localizing signals by use of simian virus 40 large T-antigen (SV40Ta) and yeast enhanced green fluoresc... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of cabbage leaves compared to gel packs for mothers with breast engorgement: Randomised controlled trial.
The effects of cold cabbage leaves and cold gel packs on breast engorgement management have been inconclusive. No studies have compared the effects of these methods on breast engorgement using a rigorou... | {
"pile_set_name": "PubMed Abstracts"
} |
Cloning and characterization of the SERK1 gene in triploid Pingyi Tiancha [Malus hupehensis (Pamp.) Rehd. var. pingyiensis Jiang] and a tetraploid hybrid strain.
This study aims to explore the roles of somatic embryogenesis receptor-like kinase (SERK) in Malus hupehensis (Pingyi Tiancha). The full-length sequences of S... | {
"pile_set_name": "PubMed Abstracts"
} |
High high-density lipoprotein-cholesterol reduces risk and extent of percutaneous coronary intervention-related myocardial infarction and improves long-term outcome in patients undergoing elective percutaneous coronary intervention.
The study tested whether high-density lipoprotein-cholesterol (HDL-C) has an effect on ... | {
"pile_set_name": "PubMed Abstracts"
} |
THE EFFECTS OF ACCLIMATION TEMPERATURE ON THE DYNAMICS OF CATECHOLAMINE RELEASE DURING ACUTE HYPOXIA IN THE RAINBOW TROUT ONCORHYNCHUS MYKISS
The response of cannulated rainbow trout (Oncorhynchus mykiss) to acute hypoxia was studied in fish acclimated to two temperatures (5 and 15 °C). Blood/water respiratory vari... | {
"pile_set_name": "PubMed Abstracts"
} |
ERK7 regulates ciliogenesis by phosphorylating the actin regulator CapZIP in cooperation with Dishevelled.
Cilia are essential for embryogenesis and maintenance of homeostasis, but little is known about the signalling pathways that regulate ciliogenesis. Here, we identify ERK7, an atypical mitogen-activated protein kin... | {
"pile_set_name": "PubMed Abstracts"
} |
New synthesis of 2 beta-hydroxy-19-oxoandrost-4-ene-3,17-dione and its 2 beta-18O analog.
Treatment of 19-[oxygenated]-androst-4-ene-3,17-dione with Mn(AcO)3 and ClCH2COOH in benzene gave epimeric mixtures of the corresponding 2 zeta-chloroacetates and 2 zeta-acetates. The products were processed to give the title comp... | {
"pile_set_name": "PubMed Abstracts"
} |
A Comparison of Brand and Biosimilar Granulocyte-Colony Stimulating Factors for Prophylaxis of Chemotherapy-Induced Febrile Neutropenia.
Filgrastim-sndz, a granulocyte-colony stimulating factor (G-CSF), was introduced as a biosimilar to filgrastim in 2015, but real-world comparative effectiveness for filgrastim versus ... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis, spectral, thermal and magnetic studies of Mn(II), Ni(II) and Cu(II) complexes with some benzopyran-4-one Schiff bases.
The Schiff bases of N(2)O(2) dibasic ligands, H(2)La and H(2)Lb are prepared by the condensation of ethylenediamine (a) and trimethylenediamine (b) with 6-formyl-7-hydroxy-5-methoxy-2-methyl... | {
"pile_set_name": "PubMed Abstracts"
} |
IFN-alpha regulates TLR-dependent gene expression of IFN-alpha, IFN-beta, IL-28, and IL-29.
Toll-like receptors (TLRs) mediate host cell activation by various microbial components. TLR2, TLR3, TLR4, TLR7, TLR8, and TLR9 are the receptors that have been associated with virus-induced immune response. We have previously r... | {
"pile_set_name": "PubMed Abstracts"
} |
New Cytotoxic Alkylated Chalcones from Fatoua villosa.
Three new alkylated chalcones, villosins A - C (1 - 3), five known analogues, together with ten known coumarins, were isolated from Fatoua villosa. The structures of the new compounds were elucidated by extensive spectroscopic analysis, including 1D-, 2D-NMR, and M... | {
"pile_set_name": "PubMed Abstracts"
} |
Syk mediates IL-17-induced CCL20 expression by targeting Act1-dependent K63-linked ubiquitination of TRAF6.
IL-17 has an important role in the immunopathogenesis of autoimmune diseases, and spleen tyrosine kinase (Syk) has been implicated as a critical molecule in the signaling pathways of various immunoreceptors. Chem... | {
"pile_set_name": "PubMed Abstracts"
} |
Thrombopoietin, but not cytokines binding to gp130 protein-coupled receptors, activates MAPKp42/44, AKT, and STAT proteins in normal human CD34+ cells, megakaryocytes, and platelets.
The development of megakaryocytes is regulated by thrombopoietin (TPO), which binds to the c-mpl receptor, and by several other cytokines... | {
"pile_set_name": "PubMed Abstracts"
} |
Short-term vitamin D3 supplementation lowers plasma renin activity in patients with stable chronic heart failure: an open-label, blinded end point, randomized prospective trial (VitD-CHF trial).
Many chronic heart failure (CHF) patients have low vitamin D (VitD) and high plasma renin activity (PRA), which are both asso... | {
"pile_set_name": "PubMed Abstracts"
} |
Immunohistochemical Cross-Reactivity Between Paracoccidioides sp. from Dolphins and Histoplasma capsulatum.
Paracoccidioidomycosis ceti is a cutaneous disease of cetaceans caused by uncultivated Paracoccidioides brasiliensis or Paracoccidioides spp. Serological cross-reactions between paracoccidioidomycosis ceti and pa... | {
"pile_set_name": "PubMed Abstracts"
} |
New cyclooxygenase-2/5-lipoxygenase inhibitors. 3. 7-tert-butyl-2, 3-dihydro-3,3-dimethylbenzofuran derivatives as gastrointestinal safe antiinflammatory and analgesic agents: variations at the 5 position.
We report an expansion of the scope of our initial discovery that 5-keto-substituted 7-tert-butyl-2,3-dihydro-3,3-... | {
"pile_set_name": "PubMed Abstracts"
} |
Thyrotropin receptor-stimulating Graves' disease immunoglobulins induce hyaluronan synthesis by differentiated orbital fibroblasts from patients with Graves' ophthalmopathy not only via cyclic adenosine monophosphate signaling pathways.
Both expression of the thyrotropin receptor (TSHR) and the production of hyaluronan... | {
"pile_set_name": "PubMed Abstracts"
} |
High-sensitivity troponin T for prediction of left ventricular function and infarct size one year following ST-elevation myocardial infarction.
Data relating high-sensitivity cardiac troponin T (hs-cTnT) to long-term myocardial function and infarct size in patients after ST-elevation myocardial infarction (STEMI) are l... | {
"pile_set_name": "PubMed Abstracts"
} |
Three sizes of subunits in RNAs from feline sarcoma-leukaemia virus mixtures.
RNA from the Snyder-Theilen feline sarcoma-leukaemia virus complex (ST-FeSV-FeLV) sedimented in a double-peaked band between 50 and 70S, but Gardner-Arnstein (GA) FeSV-FeLV RNA sedimented in a single 70S peak. FeLV isolated from the ST virus ... | {
"pile_set_name": "PubMed Abstracts"
} |
Thirteen-year randomized controlled clinical trial of a two-step self-etch adhesive in non-carious cervical lesions.
The objective of this randomized controlled clinical trial was to evaluate the 13-year clinical performance of a mild two-step self-etch adhesive in non-carious cervical lesions with and without prior se... | {
"pile_set_name": "PubMed Abstracts"
} |
THE ANALYSIS OF SPONTANEOUS CLOSURE MECHANISMS AND REGENERATION OF RETINAL LAYERS OF A FULL-THICKNESS MACULAR HOLE: Relationship with Visual Acuity Improvement.
To analyze the spontaneous closure mechanisms, retinal layer regeneration, and best corrected visual acuity (BCVA) in the full-thickness macular hole (FMTH). T... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis procedure for routine production of [carbonyl-11C]desmethyl-WAY-100635.
An improved one-pot synthesis procedure for routine production of [carbonyl-(11)C]desmethyl-WAY-100635 ([(11)C]DWAY) is described. An efficient purification of the crude product has also been developed and was accomplished by C-18 reverse... | {
"pile_set_name": "PubMed Abstracts"
} |
AP-2alpha modulates human corticotropin-releasing hormone gene expression in the placenta by direct protein-protein interaction.
Since AP-2alpha induces the expression of hPL, hCG and other syncytiotrophoblast-specific marker genes in cytotrophoblast cells during in vitro differentiation, we have examined whether AP-2a... | {
"pile_set_name": "PubMed Abstracts"
} |
Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter.
The role of ERK and Jun N-terminal kinase (JNK) in basal- and GnRH-stimulated LHbeta-promoter activity was examined in the gonadotroph cell line Lbet... | {
"pile_set_name": "PubMed Abstracts"
} |
New insights into the aggregation of silver pyrazolides using sterically hindered bidentate pyrazole ligands.
Recrystallisation of Ag[L(1)] (HL(1) = 3{5}-[pyrid-2-yl]-5{3}-tert-butylpyrazole) in the presence of halide anions leads to two polymorphs of [Ag(3)(μ-Br)(μ-L(1))(2)], which differ in their mode of supramolecul... | {
"pile_set_name": "PubMed Abstracts"
} |
Sulfimidation--a new and versatile strategy for the post ring-closure derivatisation of mixed thia/oxa crowns.
Reaction of [18]aneO(5)S with the aminating agent MSH results in the {[18]aneO(5)SNH(2)}+ cation which may be converted through to the linked crown system [({[18]aneO(5)S}(2)N)]+ via deprotonation, bromination... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of Telemedicine for the Control of Patients with Acute and Chronic Heart Diseases.
Introduction: Telemedicine (TM) has transformed the field of emergency cardiology, particularly the treatment of acute myocardial infarction (AMI). The ability to record an electrocardiogram (EKG) in the early prehospital pha... | {
"pile_set_name": "PubMed Abstracts"
} |
New delay-dependent stability criteria for neural networks with two additive time-varying delay components.
This brief is concerned with delay-dependent stability for neural networks with two additive time-varying delay components. By constructing a new Lyapunov functional and using a convex polyhedron method to estima... | {
"pile_set_name": "PubMed Abstracts"
} |
New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes.
A new series of compounds were designed as structural analogues of the alpha(1)-AR ligand RN5 (4), characterized by a tricyclic 5H-pyrimido[5,4-b]indole-(1H,3H)2,4-dione system connected through an alkyl chain to a phenylpiperazine (PP) moiety. T... | {
"pile_set_name": "PubMed Abstracts"
} |
IL28B rs12979860 gene polymorphism in Egyptian patients with chronic liver disease infected with HCV.
Egypt has one of the highest prevalences of hepatitis C virus (HCV) infection worldwide. Although the IL28B gene polymorphism has been shown to modify the course of chronic HCV infection, this has not been properly ass... | {
"pile_set_name": "PubMed Abstracts"
} |
Probing the rotational dynamics of meso-(2-substituted)aryl substituents in A2B-type subporphyrins.
A2 B-type B-methoxy subporphyrins 3 a-g and B-phenyl subporphyrins 7 a-c,e,g bearing meso-(2-substituted)aryl substituents are synthesized, and their rotational dynamics are examined through variable-temperature (VT) (1)... | {
"pile_set_name": "PubMed Abstracts"
} |
Site-specific acylation of GABA-gated Cl- channels: effects on 36Cl- uptake.
Radioligand binding studies indicate that p-isothiocyanato-t-butylbicycloorthobenzoate (p-NCS-TBOB) specifically acylates GABA-gated chloride channels. Preincubation of synaptoneurosomes with p-NCS-TBOB followed by washing resulted in a concen... | {
"pile_set_name": "PubMed Abstracts"
} |
Applications of hydrophilic disposable contact lenses as therapeutic bandages.
We employed Acuvue (Johnson & Johnson) and SeeQuence (Bausch & Lomb) disposable hydrophilic contact lenses for therapeutic purposes on 39 patients with varying pathology. Concomitant medial therapy was implemented where appropriate. The disp... | {
"pile_set_name": "PubMed Abstracts"
} |
Transesophageal echocardiography probe insertion failure in infants undergoing cardiac surgery.
The use of intraoperative transesophageal echocardiography (iTEE) in neonates ≤4 kg has not been systematically described. We sought to describe the use of and determine risk factors for iTEE probe insertion failure in small... | {
"pile_set_name": "PubMed Abstracts"
} |
Implantation of cardioverter defibrillators without induction of ventricular fibrillation.
The upper limit of vulnerability (ULV) is the weakest shock at which ventricular fibrillation (VF) is not induced by a T-wave shock. This study tested the hypothesis that a vulnerability safety margin based on the ULV can be used... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis and structural characterization of tin(II) and zinc(II) derivatives of cyclic alpha-hydroxyketones, including the structures of Sn(maltol)(2), Sn(tropolone)(2), Zn(tropolone)(2), and Zn(hinokitiol)(2).
Zinc(II) and tin(II) derivatives of maltol (Hmalt), ethylmaltol (HEtmalt), tropolone (Htrop), hinokitiol (Hh... | {
"pile_set_name": "PubMed Abstracts"
} |
Association of Irisin Circulating Level with Diabetic Retinopathy: A Case-Control Study.
Obesity and obesity induced diabetes (DM II) development and progression have been associated with sedentary lifestyle. Irisin, a newly discovered myokine, has been demonstrated at lower levels in obese and DM II patients compared ... | {
"pile_set_name": "PubMed Abstracts"
} |
New cladiellane diterpenes from the soft coral Cladiella australis of the Andaman and Nicobar Islands.
Five new cladiellane diterpenes, (1R*,2R*,3R*,6S*,7S*,9R*,10R*,14R*)-3- acetoxy-6-(3-methylbutanoyloxy)cladiell-11(17)-en-7-ol [2], (1R*,2R*,3R*,6S*,7S*,9R*, 10R*,14R*)-3-butanoyloxycladiell-11(17)-en-6,7-diol [3], (1... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis and structural characterisation of neutral pentacoordinate silicon(IV) complexes with a tridentate dianionic N,N,S chelate ligand.
A series of novel neutral pentacoordinate silicon(IV) complexes with SiClSN(2)C, SiBrSN(2)C, SiSN(3)C, SiSON(2)C, SiS(2)N(2)C, SiSeSN(2)C and SiTeSN(2)C skeletons (compounds 1-12)... | {
"pile_set_name": "PubMed Abstracts"
} |
Newest human herpesvirus (HHV-6) in the Guillain-Barré syndrome and other neurological diseases.
To investigate the presence of human herpesvirus-6 (HHV-6) in patients affected by Guillain-Barré syndrome (GBS) and by other neurological diseases (OND), we examined by indirect immunofluorescence analysis (IFA) the sera a... | {
"pile_set_name": "PubMed Abstracts"
} |
Synergistic effect of low cytotoxic linear polyethylenimine and multiarm polyethylene glycol: study of physicochemical properties and in vitro gene transfection.
Novel star-shaped copolymers consisting of multiarm polyethylene glycol and low molecular weight linear polyethylenimines (MAPEG-LPEIs) with a high transfecti... | {
"pile_set_name": "PubMed Abstracts"
} |
Imaging the photodissociation of CH3SH in the first and second absorption bands: the CH3(X2A1)+SH(X2Pi) channel.
The CH3(X2A1)+SH(X2Pi) channel of the photodissociation of CH3SH has been investigated at several wavelengths in the first 1 1A"<--X 1A' and second 2 1A"<--X1A' absorption bands by means of velocity map imag... | {
"pile_set_name": "PubMed Abstracts"
} |
Imaging the photodissociation of CH3SH in the first and second absorption bands: the CH3(X2A1)+SH(X2Pi) channel.
The CH3(X2A1)+SH(X2Pi) channel of the photodissociation of CH3SH has been investigated at several wavelengths in the first 1 1A"<--X 1A' and second 2 1A"<--X1A' absorption bands by means of velocity map imag... | {
"pile_set_name": "PubMed Abstracts"
} |
New sesquiterpenes, JBIR-27 and -28, isolated from a tunicate-derived fungus, Penicillium sp. SS080624SCf1.
In the course of our screening program for novel metabolites from tunicate-derived fungi, novel sesquiterpenoids, named JBIR-27 (1) and -28 (2), together with known sporogen-AO1 and phomenone, were isolated from ... | {
"pile_set_name": "PubMed Abstracts"
} |
Salicylamide and salicylglycine oxidovanadium complexes with insulin-mimetic properties.
Reaction of N-(2-hydroxybenzyl)-N-(2-picolyl) glycine (H(2)papy) with VOSO(4) in water gives the oxidovanadium(V) oxido-bridged dimer [{(papy)(VO)}(2) μ-O)] (1). Similarly, reaction of N-(2-hydroxybenzyl) glycine (H(2)glysal) with ... | {
"pile_set_name": "PubMed Abstracts"
} |
Predissociation of Bi2 A(0u+), v'=21-39.
Collisionless lifetimes for Bi2 A(0u+), v'=20-39, J'<or=105 have been measured using pulsed laser induced fluorescence techniques to investigate the effects of predissociation. The observed predissociation rates, Gamma=kpd(v')J(J+1), are quite rapid, ranging from kpd=1.53x10(2) ... | {
"pile_set_name": "PubMed Abstracts"
} |
Steroidal saponins from Chlorophytum deistelianum.
Phytochemical investigation of the aerial parts of Chlorophytum deistelianum led to the isolation of four previously undescribed steroidal saponins called chlorodeistelianosides A-D with five known ones. Their structures were established mainly by extensive 1D and 2D N... | {
"pile_set_name": "PubMed Abstracts"
} |
A C-terminal PDZ motif in NHE3 binds NHERF-1 and enhances cAMP inhibition of sodium-hydrogen exchange.
NHERF-1, a protein adapter containing two tandem PDZ domains, was first identified as an essential cofactor required for the phosphorylation and downregulation of NHE3 activity in response to elevated intracellular cA... | {
"pile_set_name": "PubMed Abstracts"
} |
Solid-state 31P CP/MAS and static 65Cu NMR characterization of polycrystalline copper(I) dialkyldithiophosphate clusters.
Polycrystalline tetra-nuclear Cu4[S2P(O-i-C3H7)2]4, hexa-nuclear Cu6[S2P(OC2H5)2]6, and octa-nuclear Cu8[S2P(O-i-C4H9)2]6(S) complexes were synthesized and analyzed by means of solid-state 31P CP/MA... | {
"pile_set_name": "PubMed Abstracts"
} |
Effect of preceding inspiratory speed and end-inspiratory pause on forced expiratory manoeuvre in healthy subjects and chronic obstructive pulmonary disease patients.
Lower peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV(1)) have been consistently found after slow inspiration with end-inspiratory pa... | {
"pile_set_name": "PubMed Abstracts"
} |
(R)-3,5-Bis[(E)-benzylidene]-1-(1-phenylethyl)piperidin-4-one, 3,5-bis[(E)-4-chlorobenzylidene]-1-[(R)-1-phenylethyl]piperidin-4-one and 3,5-bis[(E)-2-chlorobenzylidene]-1-[(R)-1-phenylethyl]piperidin-4-one.
Polysubstituted piperidones, viz. the title compounds, C(27)H(25)NO, (I), C(27)H(23)Cl(2)NO, (II), and C(27)H(23... | {
"pile_set_name": "PubMed Abstracts"
} |
Subcellular distributions of rat CaM kinase phosphatase N and other members of the CaM kinase regulatory system.
Ca2+/Calmodulin-dependent protein kinase (CaM kinase) regulatory system is composed of multifunctional CaM kinases such as CaM kinases IV and I, upstream CaM kinases such as CaM kinase kinases alpha and beta... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis of phosphorus ylides bearing a P-H bond from a kinetically stabilized 1,3,6-triphosphafulvene.
In mixing 2,4,6-tris(2,4,6-tri-tert-butylphenyl)-1,3,6-triphosphafulvene with alkyllithium compounds and acetic acid, both of nucleophilic alkylation and electrophilic protonation occurred at the exo sp2-phosphorus ... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of the 8th edition of the AJCC yTNM staging system shows improved prognostication in a single center cohort of esophageal carcinomas.
The 8th edition of the AJCC TNM staging system presents for the first time a specific classification for esophageal carcinomas treated with neoadjuvant therapy (yTNM8). In th... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of pediatric appropriate use criteria for initial outpatient evaluation of syncope.
Syncope is a common reason for outpatient transthoracic echocardiography (TTE). We studied the applicability of pediatric appropriate use criteria (AUC) on initial outpatient evaluation of children (≤18 years) with syncope. ... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of a bubble column for evaporative cooling and a simple procedure for determining the latent heat of vaporization of aqueous salt solutions.
In this work we have studied the evaporative cooling effect produced in a continuous flow air bubble column, containing water and salt solutions. We have established t... | {
"pile_set_name": "PubMed Abstracts"
} |
Supra-Cervical Laparoscopic Hysterectomy (SCLH) vs. Total Laparoscopic Hysterectomy (LH): A Comparative Post-Operative Study
One hundred women without cervical lesions underwent hysterectomies for uterine myomas or menometrorrhagia unresponsive to medical therapy after being randomized into two groups (50 for LH and 50... | {
"pile_set_name": "PubMed Abstracts"
} |
Two forms of vitellogenin, yielding two distinct lipovitellins, play different roles during oocyte maturation and early development of barfin flounder, Verasper moseri, a marine teleost that spawns pelagic eggs.
Two forms of vitellogenin (Vg), Vg A and Vg B, were identified in serum from estrogen-treated barfin flounde... | {
"pile_set_name": "PubMed Abstracts"
} |
Thiol protease-like active site found in the enzyme dienelactone hydrolase: localization using biochemical, genetic, and structural tools.
The active site of dienelactone hydrolase (DLH), a microbial enzyme of the beta-ketoadipate pathway, has been conclusively located using a combination of crystallographic, biochemic... | {
"pile_set_name": "PubMed Abstracts"
} |
EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16.
AGR16/H218/EDG5 and EDG1 are functional receptors for lysosphingolipids, whereas EDG2 and EGD4 are receptors for lysophosphatidic acid (LPA). The present study ... | {
"pile_set_name": "PubMed Abstracts"
} |
M8MgSc(PO4)7:xDy3+ (M = Ca/Sr) Single-Phase Full-Color Phosphor with High Thermal Emission Stability.
Two series of phosphors of Ca8MgSc(PO4)7:Dy3+ and Sr8MgSc(PO4)7:Dy3+ single-phase white-emitting phosphors with high thermal emission stability are synthesized by the high-temperature solid-state reaction. The crystal ... | {
"pile_set_name": "PubMed Abstracts"
} |
New neo-clerodane diterpenoids with neurotrophic activity from the aerial parts of Salvia tiliifolia.
Five new neo-clerodane diterpenoids, tiliifolins A-E (1-5), along with ten known ones, were isolated from the aerial part of Salvia tiliifolia. Their structures were proposed based on 1D and 2D NMR spectroscopic data a... | {
"pile_set_name": "PubMed Abstracts"
} |
Short-term effects of streptozotocin-induced diabetes on the electrocardiogram, physical activity and body temperature in rats.
A variety of contractility defects have been reported in the streptozotocin (STZ)-induced diabetic rat heart including alterations to the amplitude and time course of cardiac muscle contractio... | {
"pile_set_name": "PubMed Abstracts"
} |
Single Walled Carbon Nanohorns as Catalytic Counter Electrodes for Co(III)/(II) Electron Mediators in Dye Sensitized Cells.
The electrochemical properties of both pristine single walled carbon nanohorns (SWCNHS) and their chemically oxidized form (ox-SWCNHS) spray coated onto fluorine doped SnO2 (FTO) were investigated... | {
"pile_set_name": "PubMed Abstracts"
} |
Accuracy of CAPRA-S Score for Predicting Long-Term Biochemical Progression After Radical Prostatectomy.
The Cancer of the Prostate Risk Assessment Postsurgical (CAPRA-S) score is a tool to stratify patients into groups according to their risk for biochemical recurrence after radical prostatectomy. The aim of this study... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis and Deprotonation of Aminophosphane Complexes: First K/N(H)R Phosphinidenoid Complexes and Access to a Complex with a P2 N-Ring Ligand.
Synthesis of 1,1'-bifunctional aminophosphane complexes 3 a-e was achieved by the reaction of Li/Cl phosphinidenoid complex 2 with various primary amines (R=Me, iPr, tBu, Cy,... | {
"pile_set_name": "PubMed Abstracts"
} |
Surgical Treatment of Diverticulitis: Hand-Assisted Laparoscopic Resection Is Predominantly Used for Complex Cases and Is Associated With Increased Postoperative Complications and Prolonged Hospitalization.
Introduction Laparoscopic (LAP) colectomy is now the "gold" standard for diverticulitis; the role of hand-assiste... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis and properties of fac-Re(dmbpy)(CO)3CHO (dmbpy = 4,4'-dimethyl-2,2'-bipyridine), a possible intermediate in reductions of CO2 catalyzed by fac-Re(dmbpy)(CO)3Cl.
Synthesis of fac-Re(dmbpy)(CO)3CHO 2 and its reactions with CO2 in DMF and DMSO have been conducted; 2 transfers hydride to CO2 to give Re(dmbpy)(CO)... | {
"pile_set_name": "PubMed Abstracts"
} |
Activation of mTOR dependent signaling pathway is a necessary mechanism of antidepressant-like activity of zinc.
The rapid antidepressant response to the N-methyl-D-aspartate (NMDA) receptor antagonists is mediated by activation of the mammalian target of the rapamycin (mTOR) signaling pathway, an increase in the synth... | {
"pile_set_name": "PubMed Abstracts"
} |
New polymorph of InVO4: a high-pressure structure with six-coordinated vanadium.
A new wolframite-type polymorph of InVO4 is identified under compression near 7 GPa by in situ high-pressure (HP) X-ray diffraction (XRD) and Raman spectroscopic investigations on the stable orthorhombic InVO4. The structural transition is... | {
"pile_set_name": "PubMed Abstracts"
} |
IL28B rs12980275 and HLA rs4273729 genotypes as a powerful predictor factor for rapid, early, and sustained virologic response in patients with chronic hepatitis C.
Single-nucleotide polymorphisms (SNPs) in the Interleukin-28B (IL28B) gene and rs4273729 in the human leukocyte antigen (HLA) gene in chronic hepatitis C (... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis and oxidation of carboxylate-bridged diiron(II) complexes with substrates tethered to primary alkyl amine ligands.
The synthesis and crystallographic characterization of a series of diiron(II) complexes with sterically hindered terphenyl carboxylate ligands and alkyl amine donors are presented. The compounds ... | {
"pile_set_name": "PubMed Abstracts"
} |
New sodalite frameworks; synthetic tugtupite and a beryllosilicate framework with a 3:1 Si:Be ratio.
Compounds of the formula Na8[Si(6 +y)Be(y)Al(6 - 2y)O24]X2, with X = Cl and Br, and y = 1, 2 and 3 have been synthesised and structurally characterised by combined powder X-ray and neutron diffraction profile analysis. ... | {
"pile_set_name": "PubMed Abstracts"
} |
Applications of Perron-Frobenius theory to population dynamics.
By the use of Perron-Frobenius theory, simple proofs are given of the Fundamental Theorem of Demography and of a theorem of Cushing and Yicang on the net reproductive rate occurring in matrix models of population dynamics. The latter result, which is close... | {
"pile_set_name": "PubMed Abstracts"
} |
Appropriate Objective Functions for Quantifying Iris Mechanical Properties Using Inverse Finite Element Modeling.
Quantifying the mechanical properties of the iris is important, as it provides insight into the pathophysiology of glaucoma. Recent ex vivo studies have shown that the mechanical properties of the iris are ... | {
"pile_set_name": "PubMed Abstracts"
} |
Solvent extraction of copper(II) with chlorendic acid.
The solvent extraction of Cu(II) with chlorendic acid has been studied The composition of the extracted species appears to be a function of pH. In the pH range 3.2-4.6, a monomeric species exists [Cu(II)(L(2-)], while at pH values greater than 4.5, a dimer in the f... | {
"pile_set_name": "PubMed Abstracts"
} |
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases myocardial glucose uptake during reperfusion and induces late pre-conditioning: potential role of AMP-activated protein kinase.
Late pre-conditioning protects against myocardial ischaemic-reperfusion injury. AMP-activated protein kinase (AMPK) is activate... | {
"pile_set_name": "PubMed Abstracts"
} |
New ruminant hosts and wider geographic range identified for Babesia odocoilei (Emerson and Wright 1970).
Babesia odocoilei was found to infect two previously unknown host species, desert bighorn sheep (Ovis canadensis nelsoni) and musk oxen (Ovibos moschatus), both of which are members of the family Bovidae. Previousl... | {
"pile_set_name": "PubMed Abstracts"
} |
Appetitive characteristics in children with cystic fibrosis: Questionnaire validation and associations with nutritional status.
Appetitive characteristics are an important factor in the nutritional status of children with cystic fibrosis (CF). We administered a brief parent-report eating behavior questionnaire, validat... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis, characterization and anticancer studies of mixed ligand dithiocarbamate palladium(II) complexes.
Six mixed ligand dithiocarbamate Pd(II) complexes (1-6) of general formula [(DT)Pd(PR(3))Cl], where DT = dimethyldithiocarbamate (1, 5), diethyldithiocarbamate (2, 3), dicyclohexyldithiocarbamate (4), bis(2-metho... | {
"pile_set_name": "PubMed Abstracts"
} |
Acceleration of H+ extrusion via Na(+)-H+ exchange in guinea-pig ventricular papillary muscle under intracellular acidic condition.
We investigated mechanisms by which intracellular pH was regulated under intracellular acidic condition in resting guinea-pig ventricular papillary muscles in vitro. Intracellular sodium i... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of the Folin-Ciocalteau reagent to the determination of salbutamol in pharmaceutical preparations.
A method for the determination of salbutamol in both tablets and syrups is described. It utilizes the reduction of the Folin-Ciocalteau reagent by the phenolic group, monitoring the absorbance of the resulting... | {
"pile_set_name": "PubMed Abstracts"
} |
Gate tunable surface plasmon resonance enhanced graphene/Ag nanoparticles-polymethyl methacrylate/graphene/p-GaN heterostructure light-emitting diodes.
By combining the surface plasmon enhancement technique with gating effect, a tunable blue lighting emitting diode (LED) based on graphene/Ag nanoparticles (NPs)-polymet... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis of Bis{(2-dimethylphosphino)ethane-1-thiolato}bis(tert-butylthiolato)- molybdenum(IV) and Its Cluster-Forming Reactions with FeCl(2) and CuBr.
Reaction of Mo(S(t)Bu)(4) with 2 equiv of HSCH(2)CH(2)PMe(2) (Hdmsp) produced Mo(dmsp)(2)(S(t)Bu)(2) (1) in high yield. Treatment of 1 with FeCl(2) and CuBr led to the... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis of Bis{(2-dimethylphosphino)ethane-1-thiolato}bis(tert-butylthiolato)- molybdenum(IV) and Its Cluster-Forming Reactions with FeCl(2) and CuBr.
Reaction of Mo(S(t)Bu)(4) with 2 equiv of HSCH(2)CH(2)PMe(2) (Hdmsp) produced Mo(dmsp)(2)(S(t)Bu)(2) (1) in high yield. Treatment of 1 with FeCl(2) and CuBr led to the... | {
"pile_set_name": "PubMed Abstracts"
} |
Two binuclear cyanide-bridged Cr(III)-Mn(III) complexes based-on [Cr(2,2'-bipy)(CN)4]- building block: synthesis, crystal structures and magnetic properties.
Tetracyanide building block [Cr(2,2'-bipy)(CN)(4)]- and two bicompartimental Schiff-base based manganese(III) compounds have been employed to assemble cyanide-bri... | {
"pile_set_name": "PubMed Abstracts"
} |
Sustained norepinephrine contraction in the rat portal vein is lost when Ca(2+) is replaced with Sr(2+).
Agonist-induced activation of smooth muscle involves a rise in intracellular Ca(2+) concentration and sensitization of myosin light chain phosphorylation to Ca(2+). Sr(2+) can enter through Ca(2+) channels, be seque... | {
"pile_set_name": "PubMed Abstracts"
} |
(+/-)-Epibatidine elicits a diversity of in vitro and in vivo effects mediated by nicotinic acetylcholine receptors.
(+/-)-Epibatidine, exo-2-(6-chloro-3-pyridyl)-7-azabicyclo-[2.2.1] heptane, is a novel, potent analgesic agent that acts through nicotinic acetylcholine receptor (nAChR) mechanisms. This study sought to ... | {
"pile_set_name": "PubMed Abstracts"
} |
Should cigarette pack sizes be capped?
Very few countries regulate maximum cigarette pack size. Larger, non-standard sizes are increasingly being introduced by the tobacco industry. Larger portion sizes increase food consumption; larger cigarette packs may similarly increase tobacco consumption. Here we consider the ev... | {
"pile_set_name": "PubMed Abstracts"
} |
Allele frequencies for markers CSF1PO, TPOX, TH01, F13A01, FESFPS, vWA, D16S539, D7S820, D13S317 in the general population of Nicaragua.
General Hispanic-admixed individuals from Nicaragua. | {
"pile_set_name": "PubMed Abstracts"
} |
A bioequivalence study of the cefuroxime axetil in healthy volunteers.
The bioequivalence of 250-mg cefuroxime axetil was evaluated; Furoxime (by the Siam Bheasach Company, Thailand) as the test and Zinnat (GlaxoWellcome) as the reference. The two products were administered as a single dose according to a two-way cross... | {
"pile_set_name": "PubMed Abstracts"
} |
Rapid release of substance P and LH-RH from synaptosomes prepared from the medial basal hypothalamus and substantia nigra.
We investigated Ca2+-dependent, depolarization-induced release of substance P (SP) and LH-RH from medial basal hypothalamic (MBH) and substantia nigra (SN) synaptosomes prepared from male rat brain... | {
"pile_set_name": "PubMed Abstracts"
} |
Antigen Receptor Sequence Reconstruction and Clonality Inference from scRNA-Seq Data.
In this chapter, we describe TraCeR and BraCeR, our computational tools for reconstruction of paired full-length antigen receptor sequences and clonality inference from single-cell RNA-seq (scRNA-seq) data. In brief, TraCeR reconstruc... | {
"pile_set_name": "PubMed Abstracts"
} |
Spectroscopic properties of a series of Co(II) coordination polymers and the influence of Co(II) coordination environment on photoelectric property.
Four Co(II) coordination polymers, [Co(suc)]n 1, [Co(pdc)]n 2, {[Co7(suc)4(OH)6(H2O)3]·8H2O}n 3, {[Co(bdc)(phen)(H2O)]·H2O}n 4 (H2suc=succinic acid, H2pdc=pyridine-3,4-dic... | {
"pile_set_name": "PubMed Abstracts"
} |
Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells.
Cyclic ADP-ribose (cADP-ribose) is a putative second messenger or modulator. However, the role of cADP-ribose in the downstream signals of the metabotropic glutamate receptors... | {
"pile_set_name": "PubMed Abstracts"
} |
Trithorax-group proteins ARABIDOPSIS TRITHORAX4 (ATX4) and ATX5 function in abscisic acid and dehydration stress responses.
Trithorax-group proteins (TrxGs) play essential regulatory roles in chromatin modification to activate transcription. Although TrxGs have been shown to be extensively involved in the activation of... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis, Raman spectra and crystal structures of [Cu(XeF2)n](SbF6)2 (n=2, 4).
Pure [Cu(XeF2)2](SbF6)2 was prepared by the reaction of Cu(SbF 6) 2 with a stoichiometric amount of XeF2 in anhydrous hydrogen fluoride (aHF) at ambient temperature. The reaction between Cu(SbF6)2 and XeF2 (1:4 molar ratio) in aHF yielded [... | {
"pile_set_name": "PubMed Abstracts"
} |
Tuning State Energies for Narrow Blue Emission in Tetradentate Pyridyl-Carbazole Platinum Complexes.
Narrow, deep blue emitters are highly desired in the field of organic light emitting diodes for high quality full color display and solid-state lighting applications. PtNON is reported as a deep blue emitting phosphor b... | {
"pile_set_name": "PubMed Abstracts"
} |
Product spin-orbit state resolved dynamics of the H+H2O and H+D2O abstraction reactions.
The product state-resolved dynamics of the reactions H+H(2)O/D(2)O-->OH/OD((2)Pi(Omega);v',N',f )+H(2)/HD have been explored at center-of-mass collision energies around 1.2, 1.4, and 2.5 eV. The experiments employ pulsed laser phot... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of known triplet phases in the crystallographic study of bovine pancreatic trypsin inhibitor. I: studies at 1.55 and 1.75 a resolution.
The structure of bovine pancreatic trypsin inhibitor could be re-determined both with data at 1.55 and 1.75 A resolution using direct methods strengthened by the applicatio... | {
"pile_set_name": "PubMed Abstracts"
} |
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