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A Comparison of Brand and Biosimilar Granulocyte-Colony Stimulating Factors for Prophylaxis of Chemotherapy-Induced Febrile Neutropenia.
Filgrastim-sndz, a granulocyte-colony stimulating factor (G-CSF), was introduced as a biosimilar to filgrastim in 2015, but real-world comparative effectiveness for filgrastim versus ... | {
"pile_set_name": "PubMed Abstracts"
} |
Synovitis: a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis -- results of a 1 year longitudinal arthroscopic study in 422 patients.
To evaluate the prevalence of synovitis in painful medial tibiofemoral knee osteoarthritis (OA) and to evaluate correlation between synovi... | {
"pile_set_name": "PubMed Abstracts"
} |
Recent progress in asymmetric bifunctional catalysis using multimetallic systems.
The concept of bifunctional catalysis, wherein both partners of a bimolecular reaction are simultaneously activated, is very powerful for designing efficient asymmetric catalysts. Catalytic asymmetric processes are indispensable for produ... | {
"pile_set_name": "PubMed Abstracts"
} |
The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Recently, the effects of nutritional supplementation on improvement or prevention of polycystic ovary syndrome (PCOS) have been consi... | {
"pile_set_name": "PubMed Abstracts"
} |
Application of cabbage leaves compared to gel packs for mothers with breast engorgement: Randomised controlled trial.
The effects of cold cabbage leaves and cold gel packs on breast engorgement management have been inconclusive. No studies have compared the effects of these methods on breast engorgement using a rigorou... | {
"pile_set_name": "PubMed Abstracts"
} |
Fractionation of phosphorus and trace elements species in soybean flour and common white bean seeds by size exclusion chromatography-inductively coupled plasma mass spectrometry.
Soluble species of phosphorus, sulfur, selenium and eight metals (Mn, Fe, Co, Ni, Cu, Zn, Mo and Cd) in soybean flour and common white bean s... | {
"pile_set_name": "PubMed Abstracts"
} |
Tenecteplase: a review of its pharmacology and therapeutic efficacy in patients with acute myocardial infarction.
Tenecteplase is a triple combination mutant variant of alteplase with high fibrin specificity and resistance to plasminogen activator inhibitor-1. The reduced rate of systemic clearance of the drug relative... | {
"pile_set_name": "PubMed Abstracts"
} |
How does magnetic resonance imaging represent histologic findings in the equine digit?
Magnetic resonance (MR) imaging is increasingly used in the diagnosis of equine foot pain, but improved understanding of how MR images represent tissue-level changes in the equine foot is required. We hypothesized that alterations in... | {
"pile_set_name": "PubMed Abstracts"
} |
Effect of Early Vasopressin vs Norepinephrine on Kidney Failure in Patients With Septic Shock: The VANISH Randomized Clinical Trial.
Norepinephrine is currently recommended as the first-line vasopressor in septic shock; however, early vasopressin use has been proposed as an alternative. To compare the effect of early v... | {
"pile_set_name": "PubMed Abstracts"
} |
Multidisciplinary rounds (MDR): an implementation system for sustained improvement in the American Heart Association's Get With The Guidelines program.
Hospitals throughout the United States face the challenge of developing implementation systems able to sustain improved clinical care over years. The American Heart Ass... | {
"pile_set_name": "PubMed Abstracts"
} |
[In vitro synergistic activity of sulbactam in combination with imipenem, meropenem and cefoperazone against carbapenem-resistant Acinetobacter baumannii isolates].
Acinetobacter baumannii which is an opportunistic pathogen leading to nosocomial epidemics, exhibit high rates of antimicrobial resistance. Treatment of Ac... | {
"pile_set_name": "PubMed Abstracts"
} |
[Total intravenous anesthesia (TIVA) and balanced anesthesia with short-acting anesthetics for ENT surgery in children].
It was the aim of this study to compare total intravenous anaesthesia (TIVA) with balanced anaesthesia using modern short-acting anaesthetics for ENT-surgery in children regarding the influence on ha... | {
"pile_set_name": "PubMed Abstracts"
} |
ElaC encodes a novel binuclear zinc phosphodiesterase.
ElaC is a widespread gene found in eubacteria, archaebacteria, and mammals with a highly conserved sequence. Two human ElaC variants were recently associated with cancer (Tavtigian, S. V., Simard, J., Teng, D. H., Abtin, V., Baumgard, M., Beck, A., Camp, N. J., Car... | {
"pile_set_name": "PubMed Abstracts"
} |
Taxonomic exploration of Neotropical Microdontinae (Diptera: Syrphidae) mimicking stingless bees.
Several species of Neotropical Microdontinae (Diptera: Syrphidae) are mimics of stingless bees. Most of these species have previously been grouped in Ubristes Walker, 1852, with Carreramyia Doesburg, 1966, Hypselosyrphus H... | {
"pile_set_name": "PubMed Abstracts"
} |
Prognostic value of visceral pleural invasion in resected non-small cell lung cancer diagnosed by using a jet stream of saline solution.
Visceral pleural invasion caused by non-small cell lung cancer is a factor in the poor prognosis of patients with that disease. We investigated the relationship between the diagnosis ... | {
"pile_set_name": "PubMed Abstracts"
} |
Comparison of MRI IVIM and MR perfusion imaging in acute ischemic stroke due to large vessel occlusion.
Intravoxel incoherent motion is a diffusion-weighted imaging magnetic resonance imaging technique that measures microvascular perfusion from a multi-b value sequence. Intravoxel incoherent motion microvascular perfus... | {
"pile_set_name": "PubMed Abstracts"
} |
A model for gene evolution of the ets-1/ets-2 transcription factors based on structural and functional homologies.
The chicken c-ets-1 locus encodes two transcription factors, p54c-ets-1 and p68c-ets-1 that differ in their N-termini, encoded respectively by the I54 and alpha beta exons. p68c-ets-1 equivalents are only ... | {
"pile_set_name": "PubMed Abstracts"
} |
Efficacy of chemical root surface modifiers in the treatment of periodontal disease. A systematic review.
Periodontal regeneration has been a relentless goal of the periodontist. Perhaps the oldest and most frequently attempted type of regeneration has involved chemical modification of the root surface. Varying results... | {
"pile_set_name": "PubMed Abstracts"
} |
Minimally invasive aortic valve replacement in octogenarian, high-risk, transcatheter aortic valve implantation candidates.
Risk-stratifying algorithms are currently used to determine which patients may be at prohibitive risk for surgical aortic valve replacement, and thus candidates for transcatheter aortic valve impl... | {
"pile_set_name": "PubMed Abstracts"
} |
Incidence of mucocutaneous reactions in children treated with niflumic acid, other nonsteroidal antiinflammatory drugs, or nonopioid analgesics.
Results from a relatively small case-control study recently showed that niflumic acid increases the risk of serious mucocutaneous reactions in children. As a consequence, the ... | {
"pile_set_name": "PubMed Abstracts"
} |
Test-retest repeatability of lumbar sagittal alignment and disc height measurements with or without axial loading: a computed tomography study.
In vivo study using young healthy volunteers, CT scan, and an axial compression device. This study was conducted to evaluate the test-retest repeatability of the measurements o... | {
"pile_set_name": "PubMed Abstracts"
} |
Ambulatory blood pressure response to once-daily fimasartan: an 8-week, multicenter, randomized, double-blind, active-comparator, parallel-group study in Korean patients with mild to moderate essential hypertension.
Fimasartan, a selective angiotensin II type 1 receptor blocker, was approved in Korea for the treatment ... | {
"pile_set_name": "PubMed Abstracts"
} |
Pharmacokinetic and pharmacodynamic profile of rosuvastatin in patients with end-stage renal disease on chronic haemodialysis.
Rosuvastatin has been shown to provide effective treatment of dyslipidaemia in patients with end-stage renal disease (ESRD) undergoing haemodialysis, but data from controlled trials are very li... | {
"pile_set_name": "PubMed Abstracts"
} |
PhKv a toxin isolated from the spider venom induces antinociception by inhibition of cholinesterase activating cholinergic system.
Cholinergic agents cause antinociception by mimicking the release of acetylcholine (ACh) from spinal cholinergic nerves. PhKv is a peptide isolated from the venom of the armed spider Phoneu... | {
"pile_set_name": "PubMed Abstracts"
} |
Determination of Her-2/Neu status in breast carcinoma: comparative analysis of immunohistochemistry and fluorescent in situ hybridization.
Her-2/neu (H2N) status in breast carcinoma has been considered a prognostic factor that may have therapeutic implications; however, the correlation between H2N overexpression and ge... | {
"pile_set_name": "PubMed Abstracts"
} |
[Complete remission of nephrotic syndrome and improvement of renal function in a patient with light chain deposition disease following high dose chemotherapy with transplantation of autologous haematopoietic stem cells. A case study and review of literature].
Light chain deposition disease (LCDD) damages most frequentl... | {
"pile_set_name": "PubMed Abstracts"
} |
[Ethiopathogenesis of gastroesophageal reflux disease].
The primary cause of the gastroesophageal reflux disease is the impairment of motility and not that of acidic secretion. The reflux disease develops when the balance between aggressive and defensive factors becomes disequilibriated. Among the aggressive factors th... | {
"pile_set_name": "PubMed Abstracts"
} |
[Results of endovascular treatment of obstructive lesions of veins of the iliofemoral segment].
The purpose of the study was to assess the immediate and remote results of endovascular treatment of obstructive lesions of the veins of the iliofemoral segment. We performed balloon angioplasty and stenting for iliofemoral ... | {
"pile_set_name": "PubMed Abstracts"
} |
Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation.
Recent studies of drug-eluting intracoronary stents suggest that current antiplatelet regimens may not be sufficient to prevent late stent thrombosis. To assess the association between clopidogrel use and long-term clinical outcomes ... | {
"pile_set_name": "PubMed Abstracts"
} |
Siltuximab (Sylvant). Castleman's disease: good symptomatic efficacy in some patients.
Multicentric Castleman's disease is a rare lymphoproliferative disorder characterised by disseminated lymphadenopathy. Symptoms and outcomes differ widely from one patient to another. The median survival time is about 2.5 years. Ther... | {
"pile_set_name": "PubMed Abstracts"
} |
Abdominal computed tomography scans in the selection of patients with malignant peritoneal mesothelioma for comprehensive treatment with cytoreductive surgery and perioperative intraperitoneal chemotherapy.
Malignant peritoneal mesothelioma is a rare and fatal disease. Until recently, the treatment options were very li... | {
"pile_set_name": "PubMed Abstracts"
} |
Synaptic organization of tectal-facial pathways in cat. II. Synaptic potentials following midbrain tegmentum stimulation.
1. The organization of the synaptic pathways underlying midbrain tegmentum influence over the facial musculature was studied with the use of an acute electrophysiological approach in the cat. Under ... | {
"pile_set_name": "PubMed Abstracts"
} |
SPECT study with I-123-Ioflupane (DaTSCAN) in patients with essential tremor. Is there any correlation with Parkinson's disease?
The differential diagnosis between essential tremor (ET) and Parkinson's disease (PD) may be, in some cases, very difficult on clinical grounds alone. In addition, it is accepted that a small... | {
"pile_set_name": "PubMed Abstracts"
} |
Anatomical variation in mast cell nerve associations in the rat small intestine, heart, lung, and skin. Similarities of distances between neural processes and mast cells, eosinophils, or plasma cells in the jejunal lamina propria.
Several studies have indicated that mast cells occur in close proximity to enteric nerves... | {
"pile_set_name": "PubMed Abstracts"
} |
iTRAQ analysis of the tobacco leaf proteome reveals that RNA-directed DNA methylation (RdDM) has important roles in defense against geminivirus-betasatellite infection.
Geminiviruses have caused serious losses in crop production. To investigate the mechanisms underlying host defenses against geminiviruses, an isobaric ... | {
"pile_set_name": "PubMed Abstracts"
} |
First Report of Phytophthora ramorum and P. inflata in Ornamental Rhododendrons in Finland.
Phytophthora ramorum was found for the first time in Finland during the spring of 2004 on marketed plants of Rhododendron spp. originating in other EU member states. During August of 2004, the pathogen was also found in one Finn... | {
"pile_set_name": "PubMed Abstracts"
} |
Pharmacology of Ranolazine versus Common Cardiovascular Drugs in Patients with Early Diastolic Dysfunction Induced by Anthracyclines or Nonanthracycline Chemotherapeutics: A Phase 2b Minitrial.
We have reported that anthracyclines and nonanthracycline chemotherapeutics caused diastolic dysfunction in cancer patients wi... | {
"pile_set_name": "PubMed Abstracts"
} |
Amino acid loss and nitrogen balance in critically ill children with acute renal failure: a prospective comparison between classic hemofiltration and hemofiltration with dialysis.
Amino acid (AA) loss is not equivalent on continuous venovenous hemofiltration (CVVH) compared with continuous venovenous hemodiafiltration ... | {
"pile_set_name": "PubMed Abstracts"
} |
Self-emulsifying drug delivery systems: In vivo evaluation of their potential for oral vaccination.
Oral Immunization remains a challenge as antigens are rapidly metabolized in the gastrointestinal tract. In numerous previous studies, Self-emulsifying drug delivery systems (SEDDS) have demonstrated to be a promising to... | {
"pile_set_name": "PubMed Abstracts"
} |
Replication competence and senescence in central and peripheral human corneal endothelium.
To compare replication competence and senescence in human corneal endothelial cells (HCECs) between the central and peripheral areas and between younger and older donors. Human corneas were obtained from the eye bank and separate... | {
"pile_set_name": "PubMed Abstracts"
} |
Increased rates of pulmonary metastases following sham laparotomy compared to CO2 pneumoperitoneum and the inhibition of metastases utilizing perioperative immunomodulation and a tumor vaccine.
Subcutaneous tumor growth and establishment is increased after laparotomy; significantly smaller increases have been noted aft... | {
"pile_set_name": "PubMed Abstracts"
} |
[Effect of acute progressive normovolemic hemodilution with lactated Ringer's, gelatin and hydroxyethyl starch on coagulation and survival rate in rabbits].
To observe acute progressive normovolemic hemodilution with lactated Ringer's, gelatins, and hydroxyethyl starch in vivo and in vitro on blood coagulation and surv... | {
"pile_set_name": "PubMed Abstracts"
} |
Medium chain acyl-CoA dehydrogenase deficiency human genome epidemiology review.
Medium chain acyl-CoA dehydrogenase (MCAD) is a tetrameric flavoprotein essential for the beta-oxidation of medium chain fatty acids. MCAD deficiency (MCADD) is an inherited error of fatty acid metabolism. The gene for MCAD is located on c... | {
"pile_set_name": "PubMed Abstracts"
} |
Polycystic kidney disease: etiology, pathogenesis, and treatment.
Once viewed as hopelessly incurable disorders and the dustbin for careers in academic medicine, the polycystic kidney diseases have emerged as prime targets of pathophysiologic study and palliative and definitive treatment in the era of molecular medicin... | {
"pile_set_name": "PubMed Abstracts"
} |
[Multiple-level instrumented anterior cervical fusion: a risk factor for pseudoarthrosis? A prospective study with a minimum of 3-year follow-up].
This prospective study with minimal 3-year follow-up was performed to compare fusion rates, course of fusion, collapse incidence and occurrence of subsidence in one- and two... | {
"pile_set_name": "PubMed Abstracts"
} |
Embryonic and fetal development of structures associated with the cerebro-spinal fluid in man and other species. Part I: The ventricular system, meninges and choroid plexuses.
Little is known about the development of the central nervous system (CNS) in humans. Ethical considerations preclude experimental studies in thi... | {
"pile_set_name": "PubMed Abstracts"
} |
Oxybenziporphyrins, oxypyriporphyrins, benzocarbaporphyrins, and their 23-oxa and 23-thia analogues: synthesis, spectroscopic characterization, metalation, and structural characterization of a palladium(II) organometallic derivative.
A series of nine porphyrin analogues have been synthesized using the "3 + 1" variant o... | {
"pile_set_name": "PubMed Abstracts"
} |
[The factor analysis of the incidence of complication in CT-guided lung automated cutting needle biopsy with extrapleural locating method].
To evaluate the complication rate and analyze its impact of multiple facts of CT-guided percutaneous lung automated cutting needle biopsies (ACNB) with extrapleural locating method... | {
"pile_set_name": "PubMed Abstracts"
} |
Vasopressin improves vital organ blood flow during closed-chest cardiopulmonary resuscitation in pigs.
This study was designed to compare the effects of epinephrine with those of vasopressin on vital organ blood flow during closed-chest cardiopulmonary resuscitation (CPR) in a pig model of ventricular fibrillation. Vas... | {
"pile_set_name": "PubMed Abstracts"
} |
Her2-targeted pegylated liposomal doxorubicin: retention of target-specific binding and cytotoxicity after in vivo passage.
Receptor-directed targeting of ligand-bearing liposomes to tumor cells may enhance therapeutic efficacy by intracellular delivery of a concentrated payload of liposomal drug. The goal of this stud... | {
"pile_set_name": "PubMed Abstracts"
} |
[Effects of chronic uranium internal exposure on mortality: results of a pilot study among French nuclear workers].
This article presents the mortality data compiled among a cohort of workers at risk of internal uranium exposure and discusses the extent to which this exposure might differentiate them from other nuclear... | {
"pile_set_name": "PubMed Abstracts"
} |
Mono- and dinuclear cobalt complexes with chelating or bridging bidentate P,N phosphino- and phosphinito-oxazoline ligands: synthesis, structures and catalytic ethylene oligomerisation.
Cobalt(ii) complexes of the type [CoCl(2)(P,N)], where P,N represents a heterobidentate phosphino- or phosphinito-oxazoline-type ligan... | {
"pile_set_name": "PubMed Abstracts"
} |
Phase I and pharmacokinetic study of tomudex combined with 5-fluorouracil plus levofolinic acid in advanced head and neck cancer and colorectal cancer.
In vitro studies have shown a schedule-dependent synergism between Tomudex and 5-fluorouracil (5-FU). Incubation of different types of head and neck and colorectal canc... | {
"pile_set_name": "PubMed Abstracts"
} |
Calcium signaling is involved in ethanol-induced volume decrease and gap junction closure in cultured rat gastric mucosal cells.
Ethanol is a well-established "barrier breaker" in gastric mucosa, but its detailed effects at the cellular level remain unclear. We have previously shown that the intracellular free calcium ... | {
"pile_set_name": "PubMed Abstracts"
} |
Targeting of the Cholecystokinin-2 Receptor with the Minigastrin Analog 177Lu-DOTA-PP-F11N: Does the Use of Protease Inhibitors Further Improve In Vivo Distribution?
Patients with metastatic medullary thyroid cancer (MTC) have limited systemic treatment options. The use of radiolabeled gastrin analogs targeting the cho... | {
"pile_set_name": "PubMed Abstracts"
} |
Kinetics and mechanism of the benzenethiolysis of O-ethylS-(2,4-dinitrophenyl) and O-ethyl S-(2,4,6-trinitrophenyl) dithiocarbonates and O-methyl O-(2,4-dinitrophenyl) thiocarbonate.
Reactions of O-ethyl 2,4-dinitrophenyl dithiocarbonate (EDNPDTC), O-ethyl 2,4,6-trinitrophenyl dithiocarbonate (ETNPDTC), and O-methyl O-... | {
"pile_set_name": "PubMed Abstracts"
} |
Chromogranin A as serum marker of pituitary adenomas.
The diagnostic impact of chromogranin A (CgA) measurement has been studied in various neuroendocrine tumours (NET) such as pheochromocytomas, gastrinomas and neuroblastomas. Clinically nonfunctioning pituitary adenomas (NFPA) are generally diagnosed on tumoural symp... | {
"pile_set_name": "PubMed Abstracts"
} |
Presentation, etiology, and outcome of stroke in pregnancy and puerperium.
The purpose of this study was to evaluate the presentation, timing, etiology, and outcome of ischemic stroke (IS), hemorrhagic stroke (HS), and cerebral venous thrombosis (CVT) occurring during pregnancy and puerperium at 3 Indianapolis hospital... | {
"pile_set_name": "PubMed Abstracts"
} |
Clinical experience employing co-culture of human embryos with autologous human endometrial epithelial cells.
Attempts to improve the outcome in IVF and related techniques has drawn our attention to the development of culture systems that can grow embryos up to the blastocyst stage. We have developed a co-culture syste... | {
"pile_set_name": "PubMed Abstracts"
} |
Long-term effects of weight-reducing drugs in hypertensive patients.
All major guidelines for antihypertensive therapy recommend weight loss; anti-obesity drugs might be a helpful option. To assess the long-term effects of pharmacologically induced reduction in body weight with orlistat, sibutramine or rimonabant on:- ... | {
"pile_set_name": "PubMed Abstracts"
} |
Clinical Utility of Multiparametric Magnetic Resonance Imaging as the First-line Tool for Men with High Clinical Suspicion of Prostate Cancer.
Transrectal ultrasound-guided biopsy (TRUS-Bx) is recommended by the European Urology Association (EAU) as the first diagnostic modality for men at risk of prostate cancer (PCa)... | {
"pile_set_name": "PubMed Abstracts"
} |
Are Pulley Exercises Initiated 6 Weeks After Rotator Cuff Repair a Safe and Effective Rehabilitative Treatment? A Randomized Controlled Trial.
There are few level 1 or 2 evidence studies that examine rehabilitation after rotator cuff repair. Pulleys have been used in postoperative shoulder rehabilitation with the inten... | {
"pile_set_name": "PubMed Abstracts"
} |
Knee Recurvatum in Children With Spastic Diplegic Cerebral Palsy.
The purpose of this study is to determine which factors drive patients with diplegic cerebral palsy to walk without knee recurvatum despite hyperextension of the knee on physical examination. A retrospective review was conducted of all data collected in ... | {
"pile_set_name": "PubMed Abstracts"
} |
Epitope mapping of the human biliary amphipathic, anionic polypeptide: similarity with a calcium-binding protein isolated from gallstones and bile, and immunologic cross-reactivity with apolipoprotein A-I.
Biliary amphipathic anionic polypeptide (APF) the major protein of the pigment-lipoprotein complex in bile, and ca... | {
"pile_set_name": "PubMed Abstracts"
} |
Prevalence of feline heartworm infections among cats with respiratory and gastrointestinal signs: results of a multicenter study.
Although heartworm infection in cats was first described in 1921, the diagnosis of the infection remains elusive in many cases. This is due to nonspecific clinical signs of feline heartworm ... | {
"pile_set_name": "PubMed Abstracts"
} |
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