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Episodes of atrial fibrillation and meteorological conditions.
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. The natural history of AF tends to begin with short paroxysms which gradually evolve into longer episodes, frequently treatment-resistant, and finally take a permanent ... | {
"pile_set_name": "PubMed Abstracts"
} |
A single-institution retrospective cases series of childhood undifferentiated embryonal liver sarcoma (UELS): success of combined therapy and the use of orthotopic liver transplant.
Undifferentiated embryonal liver sarcoma (UELS) makes up 9% to 15% of all malignant liver tumors in children. UELS is characteristically d... | {
"pile_set_name": "PubMed Abstracts"
} |
Presbyopia and near spectacle correction coverage among public school teachers in Ifo Township, South-West Nigeria.
Presbyopia is an age-related loss of lens accommodation resulting in difficulty in performing near task with attendant effect on the quality of life. The objective of the study was to determine the preval... | {
"pile_set_name": "PubMed Abstracts"
} |
NTP Lifetime Carcinogenesis Studies of Chrysotile Asbestos (CAS No. 12001-29-5) in Syrian Golden Hamsters (Feed Studies).
NTP Carcinogenesis studies of short range (SR), intermediate range (IR), or intermediate range chrysotile asbestos in combination with the intestinal carcinogen 1,2-dimethylhydrazine dihydrochloride... | {
"pile_set_name": "PubMed Abstracts"
} |
Do gastrointestinal symptoms accompanying sore throat predict streptococcal pharyngitis? An UPRNet study. Upper Peninsula Research Network.
The purpose of this study was to determine whether gastrointestinal (GI) symptoms are more common in streptococcal than nonstreptococcal pharyngitis, and, if so, whether these symp... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat.
A series of experiments were conducted to examine the potential role of phase I metabolism in halothane-induced liver injury in the hyperthyroid rat. The metabolism of halothane was determined in both hyperthyroid (triiodo... | {
"pile_set_name": "PubMed Abstracts"
} |
Influence of dietary lysine on the utilization of zinc from zinc sulfate and a zinc-lysine complex by young pigs.
We conducted two trials (n = 144 and 96) to evaluate the response of feeding either ZnSO4 x H2O or a zinc-lysine complex (ZnLys) in combination with various lysine levels on growth performance, liver, kidne... | {
"pile_set_name": "PubMed Abstracts"
} |
Insulin secretory responses in patients with glucose intolerance due to extra-pancreatic causes. Comparison with idiopathic diabetes mellitus.
Insulin responses during 100 g glucose tolerance tests (GTT) were compared between three groups of patients with varying degrees of glucose intolerance. Patients who had no dise... | {
"pile_set_name": "PubMed Abstracts"
} |
Changes of macrovascular endothelial ultrastructure and gene expression of endothelial nitric oxide synthase in diabetic rats.
The most intimidatory pathological changes in patients with DM are cardiovascular illnesses, which are the major causes of death in diabetic patients and are far more prevalent than in nondiabe... | {
"pile_set_name": "PubMed Abstracts"
} |
The effect of bexarotene on atorvastatin pharmacokinetics: results from a phase I trial of bexarotene plus chemotherapy in patients with advanced non-small cell lung cancer.
Bexarotene (Targretin(®) capsules) is a retinoid-X-receptor agonist and an inducer of CYP3A4-mediated metabolism. This phase I trial evaluated the... | {
"pile_set_name": "PubMed Abstracts"
} |
Symptoms and the distress they cause: comparison of an aldosterone antagonist and a calcium channel blocking agent in patients with systolic hypertension.
Although there has been increasing recognition that a substantial part of the cardiovascular, central nervous system, and renal conditions induced by renin-angiotens... | {
"pile_set_name": "PubMed Abstracts"
} |
Changes in axonal physiology and morphology after chronic compressive injury of the rat thoracic spinal cord.
The spinal cord is rarely transected after spinal cord injury. Dysfunction of surviving axons, which traverse the site of spinal cord injury, appears to contribute to post-traumatic neurological deficits, altho... | {
"pile_set_name": "PubMed Abstracts"
} |
Her2-targeted pegylated liposomal doxorubicin: retention of target-specific binding and cytotoxicity after in vivo passage.
Receptor-directed targeting of ligand-bearing liposomes to tumor cells may enhance therapeutic efficacy by intracellular delivery of a concentrated payload of liposomal drug. The goal of this stud... | {
"pile_set_name": "PubMed Abstracts"
} |
Clinicopathological characterization of TSH-producing adenomas: special reference to TSH-immunoreactive but clinically non-functioning adenomas.
Thyrotropin (thyroid-stimulating hormone (TSH))-producing pituitary adenomas have been known to be quite variable in clinical features covering from typical functioning TSH-pr... | {
"pile_set_name": "PubMed Abstracts"
} |
A rainbow ratiometric fluorescent sensor array on bacterial nanocellulose for visual discrimination of biothiols.
Considering the crucial role of biothiols in many biological processes, which turns them into highly valuable biomarkers for the early diagnosis of various diseases, the development of an affordable, sensit... | {
"pile_set_name": "PubMed Abstracts"
} |
Thermosensitive hydrogel system assembled by PTX-loaded copolymer nanoparticles for sustained intraperitoneal chemotherapy of peritoneal carcinomatosis.
Intraperitoneal (IP) chemotherapy is a preferable treatment option for peritoneal carcinomatosis of malignancies by delivering chemotherapeutic drugs into the abdomina... | {
"pile_set_name": "PubMed Abstracts"
} |
Cefepime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.
Cefepime is a 'fourth' generation cephalosporin that has a broader spectrum of antibacterial activity than the third generation cephalosporins and is more active in vitro against Gram-positive aerobic bacteria. The fact th... | {
"pile_set_name": "PubMed Abstracts"
} |
Melatonin as add-on treatment for epilepsy.
This is an updated version of the original Cochrane review published in Issue 6, 2012.Epilepsy is one of the most common chronic neurological disorders. Despite the plethora of antiepileptic drugs (AEDs) currently available, 30% of people continue having seizures. This group ... | {
"pile_set_name": "PubMed Abstracts"
} |
Infectious complications of human bone marrow transplantation.
Infections are an almost inevitable complication of human bone marrow transplantation and account for the majority of deaths in transplant recipients. Even prior to the initiation of the transplantation procedure, patients may present with infections compli... | {
"pile_set_name": "PubMed Abstracts"
} |
The Patient Experience of Hemophilia and Human Immunodeficiency Virus: A Systematic Review of Qualitative Evidence.
The objective of this review is to describe and synthesize the experiences and perspectives of illness for patients living with both hemophilia and human immunodeficiency virus (HIV). Hemophilia is an inh... | {
"pile_set_name": "PubMed Abstracts"
} |
Prevalence of Immunodeficiency in Children With Invasive Pneumococcal Disease in the Pneumococcal Vaccine Era: A Systematic Review.
Despite increasing access to vaccination, invasive pneumococcal disease (IPD) is responsible for approximately 826 000 deaths worldwide in children younger than 5 years each year. To allow... | {
"pile_set_name": "PubMed Abstracts"
} |
[Emil Kraepelin: a pioneer of modern psychiatry. On the occasion of the hundred and fiftieth anniversary of his birth].
Emil Kraepelin (1856-1926) whose hundred and fiftieth birth anniversary we are celebrating this year, is one of the most renowned figures of psychiatry. His Memoirs published in 1983 provide insight o... | {
"pile_set_name": "PubMed Abstracts"
} |
Clinical Utility of Multiparametric Magnetic Resonance Imaging as the First-line Tool for Men with High Clinical Suspicion of Prostate Cancer.
Transrectal ultrasound-guided biopsy (TRUS-Bx) is recommended by the European Urology Association (EAU) as the first diagnostic modality for men at risk of prostate cancer (PCa)... | {
"pile_set_name": "PubMed Abstracts"
} |
Methods for obtaining unpublished data.
In order to minimise publication bias, authors of systematic reviews often spend considerable time trying to obtain unpublished data. These include data from studies conducted but not published (unpublished data), as either an abstract or full-text paper, as well as missing data ... | {
"pile_set_name": "PubMed Abstracts"
} |
Obesity in Malaysia.
This study was undertaken to assess the recent data on Malaysian adult body weights and associations of ethnic differences in overweight and obesity with comorbid risk factors, and to examine measures of energy intake, energy expenditure, basal metabolic rate (BMR) and physical activity changes in ... | {
"pile_set_name": "PubMed Abstracts"
} |
[Management of Lung Abscess].
A lung abscess is an infectious pulmonary disease characterised by the presence of a pus-filled cavity within the lung parenchyma. The content of an abscess often drains into the airways spontaneously, leading to an air-fluid level visible on chest X-rays and CT scans. Primary lung abscess... | {
"pile_set_name": "PubMed Abstracts"
} |
Caries experience, oral disorders, oral hygiene practices and socio-demographic characteristics of autistic children.
The aim of the present study was to comparatively evaluate the oral health status and influential factors, brushing, developmental and orthodontic disorders, bruxism, drug intake, sweet eating habits, s... | {
"pile_set_name": "PubMed Abstracts"
} |
Overview and expert assessment of off-label use of misoprostol in obstetrics and gynaecology: review and report by the Collège national des gynécologues obstétriciens français.
The literature suggests that misoprostol can be offered to patients for off-label use as it has reasonable efficacy, risk/benefit ratio, tolera... | {
"pile_set_name": "PubMed Abstracts"
} |
A comparison of the efficacy and safety of ceftizoxime with doxycycline versus conventional CDC therapies in the treatment of upper genital tract infection with or without a mass.
It is well known that sexually transmitted infections of the upper genital tract are widespread. A variety of regimens are used to treat the... | {
"pile_set_name": "PubMed Abstracts"
} |
Structure-function relations of antithrombin III-heparin interactions as assessed by biophysical and biological assays and molecular modeling of peptide-pentasaccharide-docked complexes.
The serine proteinase inhibitor antithrombin III (ATIII) is a key regulatory protein of intrinsic blood coagulation. ATIII attains it... | {
"pile_set_name": "PubMed Abstracts"
} |
The effect of left-behind phenomenon and physical neglect on behavioral problems of children.
Left-behind children have a high incidence of behavioral problems in some Eastern countries, especially China. We sought to assess the combined effects of physical neglect, a major embodiment of the left-behind phenomenon, and... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of chemical stimulation of masseter muscle nociceptors on trigeminal motoneuron and interneuron activities during fictive mastication in the rabbit.
An electrophysiological study was carried out in sixteen decerebrate and paralyzed New Zealand rabbits to determine how a bolus injection of a nociceptor stimulant... | {
"pile_set_name": "PubMed Abstracts"
} |
Possible involvement of cathepsin B/D and caspase-3 in deferoxamine-related neuroprotection of early brain injury after subarachnoid haemorrhage in rats.
Deferoxamine (DFX) has recently been shown to have a neuroprotective effect in animal models of subarachnoid haemorrhage (SAH). However, the precise mechanisms underl... | {
"pile_set_name": "PubMed Abstracts"
} |
Pharmacokinetic and pharmacodynamic profile of rosuvastatin in patients with end-stage renal disease on chronic haemodialysis.
Rosuvastatin has been shown to provide effective treatment of dyslipidaemia in patients with end-stage renal disease (ESRD) undergoing haemodialysis, but data from controlled trials are very li... | {
"pile_set_name": "PubMed Abstracts"
} |
Patterns of care for patients with primary differentiated carcinoma of the thyroid gland treated in Germany during 1996. U.S. and German Thyroid Cancer Group.
To determine current patterns of care and disease characteristics for patients with thyroid carcinoma, a Patient Care Evaluation Study was initiated in 1996 in t... | {
"pile_set_name": "PubMed Abstracts"
} |
Comparative tooth whitening and extrinsic tooth stain removal efficacy of two tooth whitening dentifrices: six-week clinical trial.
The objective of this six-week, examiner-blind clinical study was to assess the tooth whitening and extrinsic tooth stain removal efficacy of a new dentifrice delivering 1.0% hydrogen pero... | {
"pile_set_name": "PubMed Abstracts"
} |
Nerve growth factor receptor immunoreactivity in the rat septohippocampal pathway: a light and electron microscope investigation.
Nerve growth factor receptor immunoreactivity in the septohippocampal pathway of adult Fischer 344 rats was assessed at the light and electron microscope level. The medial septum possesses i... | {
"pile_set_name": "PubMed Abstracts"
} |
The organochlorine pesticide heptachlor disrupts the structure of model and cell membranes.
Heptachlor is an organochlorine pesticide which is particularly toxic for aquatic life. A significant source of this pesticide for infants is breast milk, where its concentration is considerably higher than in dairy milk. Given ... | {
"pile_set_name": "PubMed Abstracts"
} |
Impact of biocontrol strain Pseudomonas fluorescens CHA0 on rhizosphere bacteria isolated from barley (Hordeum vulgare L.) with special reference to Cytophaga-like bacteria.
To assess the impact of the biocontrol strain Pseudomonas fluorescens CHA0 on a collection of barley rhizosphere bacteria using an agar plate inhi... | {
"pile_set_name": "PubMed Abstracts"
} |
TPP-dendrimer nanocarriers for siRNA delivery to the pulmonary epithelium and their dry powder and metered-dose inhaler formulations.
The regulation of genes utilizing the RNA interference (RNAi) mechanism via the delivery of synthetic siRNA has great potential in the treatment of a variety of lung diseases. However, t... | {
"pile_set_name": "PubMed Abstracts"
} |
NTP toxicity studies of carisoprodol (CAS No. 78-44-4) administered by Gavage to F344/N rats and B6C3F1 mice.
[carisoprodol structure: see text] Carisoprodol is a widely used skeletal muscle relaxant and analgesic and is available as a prescription drug. Comparative studies were conducted to determine the toxicity of c... | {
"pile_set_name": "PubMed Abstracts"
} |
Antibiotic susceptibility of acute otitis media pathogens in otitis-prone Belgian children.
A regional surveillance study was carried out in children with recurrent acute otitis media (AOM) to determine the antimicrobial susceptibility of three common AOM pathogens. Susceptibility to relevant antimicrobial agents was d... | {
"pile_set_name": "PubMed Abstracts"
} |
Tension viscerothorax after blunt abdominal trauma: a case report and review of the literature.
Tension viscerothorax is herniation of abdominal viscera into the thorax. Tension viscerothorax can simulate tension pneumothorax. Immediate decompression with a nasogastric tube is required for hemodynamic stabilization. A ... | {
"pile_set_name": "PubMed Abstracts"
} |
The safety of newer antidepressants in pregnancy and breastfeeding.
The pregnancy and postpartum periods are considered to be relatively high risk times for depressive episodes in women, particularly for those with pre-existing psychiatric illnesses. Therefore, it may be necessary to start or continue the pharmacologic... | {
"pile_set_name": "PubMed Abstracts"
} |
Double-blind trials of azelastine nasal spray monotherapy versus combination therapy with loratadine tablets and beclomethasone nasal spray in patients with seasonal allergic rhinitis. Rhinitis Study Groups.
Azelastine hydrochloride is an H1-receptor antagonist with antiinflammatory properties that is available in the ... | {
"pile_set_name": "PubMed Abstracts"
} |
Factors affecting the changes in amphotericin sensitivity of Candida albicans during growth.
The sensitivity of Candida albicans, grown in batch culture at 37 degrees C, to amphotericin methyl ester (AME), judged by the concentration of AME required to induce a standard rate of leakage of K+ from suspensions of organis... | {
"pile_set_name": "PubMed Abstracts"
} |
Occurrence of autoimmunity after xenothymus transplantation in T-cell-deficient mice depends on the thymus transplant technique.
Xenothymus transplantation under the kidney capsule in athymic rodents frequently leads to multiorgan autoimmunity. Herein, we explore whether this is an intrinsic risk of xenothymus grafting... | {
"pile_set_name": "PubMed Abstracts"
} |
Expression and prognosis of MYOZ2 in gastric cancer.
To investigate the expression of human myozenin 2 (MYOZ2) in cancer tissues and its effect on the prognosis of patients with gastric cancer. Gastric cancer tissue and adjacent normal tissue specimens were obtained from a total of 258 patients together with complete c... | {
"pile_set_name": "PubMed Abstracts"
} |
Pharmacologic and surgical treatment of dyslipidemic children and adolescents.
A wide variety of treatment modalities have been used in children with dyslipidemias to reduce the concentrations of atherogenic lipoprotein particles. Most of the published experience has focused upon children with familial hypercholesterol... | {
"pile_set_name": "PubMed Abstracts"
} |
Bone mineral density in children with myelomeningocele.
Difficulties with ambulation in patients with myelomeningocele often lead to physical inactivity, osteoporosis, and subsequent development of pathologic fractures. The purpose of this study was to examine bone mineral density and biochemical markers of bone metabo... | {
"pile_set_name": "PubMed Abstracts"
} |
In vitro activity of various antibiotics against clinical strains of Legionella species isolated in Japan.
The activities of various antibiotics against 58 clinical isolates of Legionella species were evaluated using two methods, extracellular activity (minimum inhibitory concentration [MIC]) and intracellular activity... | {
"pile_set_name": "PubMed Abstracts"
} |
Morphology and histology of the digestive system of the vector leafhopper Psammotettix striatus (L.) (Hemiptera: Cicadellidae).
The vector leafhopper Psammotettix striatus (L.) (Hemiptera: Cicadellidae) is an important economic pest that is a serious threat to wheat in Northwest China, causing great losses to agricultu... | {
"pile_set_name": "PubMed Abstracts"
} |
Accumulation of HMX (octahydro-1,3,5,7-tetranitro-1,3,5,7-tetrazocine) in indigenous and agricultural plants grown in HMX-contaminated anti-tank firing-range soil.
To investigate their potential for phytoremediation, selected agricultural and indigenous terrestrial plants were examined fortheir capacity to accumulate a... | {
"pile_set_name": "PubMed Abstracts"
} |
Presentation, etiology, and outcome of stroke in pregnancy and puerperium.
The purpose of this study was to evaluate the presentation, timing, etiology, and outcome of ischemic stroke (IS), hemorrhagic stroke (HS), and cerebral venous thrombosis (CVT) occurring during pregnancy and puerperium at 3 Indianapolis hospital... | {
"pile_set_name": "PubMed Abstracts"
} |
Clinical and bacteriological efficacy of the ketolide telithromycin against isolates of key respiratory pathogens: a pooled analysis of phase III studies.
A pooled analysis of data from 13 phase III studies of telithromycin in the treatment of community-acquired pneumonia, acute exacerbations of chronic bronchitis, acu... | {
"pile_set_name": "PubMed Abstracts"
} |
Activation of the baboon fetal hypothalamic-pituitary-adrenocortical axis at midgestation by estrogen-induced changes in placental corticosteroid metabolism.
We have hypothesized that the change in placental cortisol (F)-cortisone (E) metabolism induced by estrogen late in gestation is important to activation of the ba... | {
"pile_set_name": "PubMed Abstracts"
} |
The morphology of acute disc herniation: a clinically relevant model defining the role of flexion.
Hydrostatically induced disruption of flexed lumbar intervertebral discs followed by microstructural investigation. To investigate how flexion affects the anulus' ability to resist rupture during hydrostatic loading, and ... | {
"pile_set_name": "PubMed Abstracts"
} |
Piretanide. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Piretanide is a potent 'loop' diuretic whose principal site of action is in the thick ascending limb of the loop of Henle. When administered orally or intravenously to healthy volunteers it rapidly increase... | {
"pile_set_name": "PubMed Abstracts"
} |
Study of Relationship Between Illness Perception and Delay in Seeking Help for Breast Cancer Patients Based on Leventhal's Self-Regulation Model.
One of the major causes of morbidity and mortality in breast cancer patients is delay in seeking help. Leventhal's self-regulation model provides an appropriate framework to ... | {
"pile_set_name": "PubMed Abstracts"
} |
Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors.
In the proliferative zone of the developing cerebral cortex, multipotential progenitors predominate early in development and divide to increase the progenitor pool. As cor... | {
"pile_set_name": "PubMed Abstracts"
} |
[Study on potentiation of nitrosourea-cytotoxicity by DNA repair enzyme inhibitors in human brain tumor cells].
Nitrosoureas are antitumor alkylating agents widely used in the chemotherapy of malignant brain tumors. However, the effectiveness of adjuvant nitrosourea chemotherapy has proved inadequate, failing to provid... | {
"pile_set_name": "PubMed Abstracts"
} |
The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2).
Hermansky-Pudlak syndrome (HPS) is a genetically heterogeneous inherited disease affecting vesicle trafficking among lysosome-related organelles. The Hps3, Hps5, and Hps6 genes are mutated... | {
"pile_set_name": "PubMed Abstracts"
} |
Effect of Pregnancy on Performance of a Standardized Physical Fitness Test.
Research has demonstrated the positive effects of exercise during pregnancy on maternal and fetal outcomes, but very little research has evaluated the effect of pregnancy on women's fitness or the length of time needed to recover prepregnancy f... | {
"pile_set_name": "PubMed Abstracts"
} |
Use of doxycycline to decrease the growth rate of abdominal aortic aneurysms: a randomized, double-blind, placebo-controlled pilot study.
Eradication of Chlamydia pneumoniae infection and inhibition of elastolytic matrix metalloproteinases with doxycycline have been suggested to reduce the growth rates of small abdomin... | {
"pile_set_name": "PubMed Abstracts"
} |
The hustle and bustle of city life: monitoring the effects of urbanisation in the African lesser bushbaby.
Urbanisation has become a severe threat to pristine natural areas, causing habitat loss and affecting indigenous animals. Species occurring within an urban fragmented landscape must cope with changes in vegetation... | {
"pile_set_name": "PubMed Abstracts"
} |
Consensus on "Basal insulin in the management of Type 2 Diabetes: Which, When and How?"
Type 2 diabetes mellitus (T2DM) has attained epidemic proportions and continues to increase despite the availability of a number of oral antidiabetic medications and major advances made in insulin delivery since its discovery nearly... | {
"pile_set_name": "PubMed Abstracts"
} |
Safety profile of oral and intravenous moxifloxacin: cumulative data from clinical trials and postmarketing studies.
The established safety profile of the fluoroquinolones has been disrupted in the past decade by the detection of low-frequency but potentially serious adverse events that have led to the license suspensi... | {
"pile_set_name": "PubMed Abstracts"
} |
Towards functional 3D-stacked electrospun composite scaffolds of PHBV, silk fibroin and nanohydroxyapatite: Mechanical properties and surface osteogenic differentiation.
Bone tissue engineering scaffolds have two challenging functional tasks to fulfil: to encourage cell proliferation, differentiation and matrix synthes... | {
"pile_set_name": "PubMed Abstracts"
} |
A changing culture in interpersonal and communication skills.
In summary it is essential that we improve our interpersonal and communication skills. We can learn and be taught better skills. We will be evaluated on these skills in the future, and it is important for us to establish ourselves as good role models for the... | {
"pile_set_name": "PubMed Abstracts"
} |
Laminar distribution of neurotransmitter receptors in different reeler mouse brain regions.
Mapping of multiple receptors of neurotransmitters provides insight into the spatial distribution of neurotransmission-relevant molecules in the cerebral cortex. During development, lack of reelin leads to impaired migration, di... | {
"pile_set_name": "PubMed Abstracts"
} |
Pathology and toxicology of beluga whales from the St. Lawrence Estuary, Quebec, Canada. Past, present and future.
An indigenous population of 450-500 beluga whales (Delphinapterus leucas) inhabiting the St. Lawrence Estuary has been exposed chronically for more than 50 years to a complex mixture of industrial pollutan... | {
"pile_set_name": "PubMed Abstracts"
} |
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