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How is Advanced organizing pneumonia, featuring transformation of exudates to fibromyxoid masses infiltrate?
by macrophages and fibroblasts
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What are infiltrated with lymphocytes and some plasma cells, which spill over into alveolar spaces?
the thickened alveolar walls
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What are the thickened alveolar walls infiltrated with?
lymphocytes and some plasma cells
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What are filled with a characteristic foamy acellular exudate?
the alveoli
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What are the alveoli filled with?
a characteristic foamy acellular exudate
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What does the histologic appearance demonstrate?
small
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What shows mesangial cell proliferation, basement membrane duplication, leukocyte infiltration, and accentuation of lobular architecture?
membranoproliferative glomerulonephritis (mpgn)
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What shows complete replacement of virtually all glomeruli by blue-staining collagen?
a masson trichrome preparation
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What does a Masson trichrome preparation show?
complete replacement of virtually all glomeruli by blue-staining collagen
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How does a Masson trichrome preparation show complete replacement of virtually all glomeruli?
by blue-staining collagen
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What remain within the predominantly metaplastic, reddish mucosa of the distal esophagus?
a few areas of pale squamous mucosa
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What do only a few areas of pale squamous mucosa remain within?
the predominantly metaplastic
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What is composed of nests of malignant cells that partially recapitulate the stratified organization of squamous epithelium?
squamous cell carcinoma
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What are highlighted in this Warthin-Starry silver stain?
spiral-shaped helicobacter pylori bacilli
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How are spiral-shaped Helicobacter pylori bacilli?
highlighted in this warthin-starry silver stain
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What are abundant within surface mucus?
organisms
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What are organisms abundant within?
surface mucus
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What are prominent?
intraepithelial and lamina propria neutrophils
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What is composed of granulation tissue overlaid by degraded blood?
the necrotic ulcer base
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What is the necrotic ulcer base composed of?
granulation tissue overlaid by degraded blood
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What is markedly thickened?
the gastric wall
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Infiltration of the surface epithelium by T lymphocytes , which can be recognized by whose stained nuclei labeled T ?
their
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What shows regularly spaced stool-filled diverticulae?
gross examination of a resected sigmoid colon
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What are cut in cross-section?
glands
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How are the glands cut?
in cross-section
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What produces a serrated architecture when glands are cut in cross-section?
epithelial crowding
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What does epithelial crowding produce when glands are cut in cross-section?
a serrated architecture
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What are present along with a dominant polyp (right)?
hundreds of small colonic polyps
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What are hundreds of small colonic polyps present along with?
a dominant polyp
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What are present within the colon wall?
areas of chalky necrosis
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Where are areas of chalky necrosis present?
within the colon wall
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What is typical?
necrotic debris
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What is small (700 g), bile-stained, soft, and congested?
the liver
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How much does the liver weigh?
700 g
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How is the liver?
small (700g)
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What is entrapped in a dense, onion-skin concentric scar?
a bile duct undergoing degeneration
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What is a bile duct undergoing degeneration entrapped in?
a dense
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What is removed at autopsy showing a unifocal, massive neoplasm replacing most of the right hepatic lobe in a noncirrhotic liver?
the liver
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What replaced most of the right hepatic lobe in a noncirrhotic liver?
neoplasm
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What is infiltrated by chronic inflammatory cells?
the gallbladder mucosa
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What is the gallbladder mucosa infiltrated by?
chronic inflammatory cells
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What compress the urethra into a slitlike lumen?
well-defined nodules
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What do well-defined nodules compress?
the urethra into a slitlike lumen
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What is seen on the posterior aspect (lower left)?
carcinomatous tissue
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Where is carcinomatous tissue seen ?
on the posterior aspect
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What is caused by gonococcal infection?
acute epididymitis
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What is acute epididymitis caused by?
gonococcal infection
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How is acute epididymitis caused?
by gonococcal infection
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What is involved by an abscess?
the epididymis
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What is seen on the right?
normal testis
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Where is normal testis seen?
on the right
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What is characterized by increased numbers of epithelial cells, as in this example of epithelial hyperplasia?
proliferative breast disease
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What is proliferative breast disease characterized by?
an increased numbers of epithelial cells
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What tend to be larger at the time of diagnosis than those that secrete a hormone?
nonfunctioning adenomas
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What do nonfunctioning adenomas tend to be?
larger at the time of diagnosis than those that secrete hormone
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What contains areas of fibrosis and cystic change?
the coarsely nodular gland
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What does the coarsely nodular gland contain?
areas of fibrosis and cystic change
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The hyperplastic follicles contain abundant pink colloid within whose lumina ?
their
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What contain abundant pink colloid within their lumina?
the hyperplastic follicles
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What do the hyperplastic follicles contain?
abundant pink colloid within their lumina
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The hyperplastic follicles contain abundant pink colloid within whose lumina ?
their
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What surrounds the neoplastic follicles?
a fibrous capsule
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What is derived from calcitonin molecules secreted by the neoplastic cells?
amyloid
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What contain amyloid derived from calcitonin molecules secreted by the neoplastic cells?
medullary carcinoma tumors
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What do these tumors contain?
amyloid derived from calcitonin molecules secreted by the neoplastic cells
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What is delineated from the residual normocellular gland on the upper right in this low-power view?
a solitary hypercellular adenoma
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What is a solitary hypercellular adenoma delineated from?
the residual normocellular gland on the upper right
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What shows minimal variation in nuclear size and occasional follicle formation?
high-power detail
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What is contrasted with a normal adrenal gland?
diffuse hyperplasia of the adrenal gland
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What is diffuse hyperplasia of the adrenal gland contrasted with?
a normal adrenal gland
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How is diffuse hyperplasia of the adrenal gland contrasted?
with a normal adrenal gland
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What is yellow and thickened?
the adrenal cortex
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What were diffusely hyperplastic?
adrenal glands in a patient with acth-dependent cushing syndrome
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What was from a patient with ACTH-dependent Cushing syndrome, in whom both adrenal glands were diffusely hyperplastic?
the adnormal gland
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What was the abnormal gland from?
a patient with acth-dependent cushing syndrome
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How was the abnormal gland?
from a patient with acth-dependent cushing syndrome
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What result in acute adrenal insufficiency?
bilateral adrenal hemorrhage
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What did bilateral adrenal hemorrhage in an infant with overwhelming sepsis result in?
acute adrenal insufficiency
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What is discernible in this photomicrograph?
little residual cortical architecture
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What were grossly hemorrhagic and shrunken at autopsy?
the adrenal glands
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What entraps native lamellar bone as a confluent mass of cartilage?
conventional chondrosarcoma
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What is composed of sheets of small round cells with small amounts of clear cytoplasm?
ewing sarcoma
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What is Ewing sarcoma composed of?
sheets of small round cells with small amounts of clear cytoplasm
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How is Ewing sarcoma composed of sheets of small round cells?
with small amounts of clear cytoplasm
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What is surrounded by a fibrous wall containing proliferating fibroblasts, reactive woven bone, and osteoclast-type giant cells?
aneurysmal bone cyst with blood-filled cystic space
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What is the aneurysmal bone cyst with blood-filled cystic space surrounded by?
a fibrous wall containing proliferating fibroblasts
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How is aneurysmal bone cyst with blood-filled cystic space surrounded?
by a fibrous wall containing proliferating fibroblasts
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What is composed of curvilinear trabeculae of woven bone that lack conspicuous osteoblastic rimming and arise in a background of fibrous tissue?
fibrous dysplasia
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What is fibrous dysplasia composed of?
curvilinear trabeculae of woven bone
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What contains a dense lymphoid aggregate?
subsynovial tissue
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What did subsynovial tissue contain?
a dense lymphoid aggregate
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What allow for examination of individual axons of peripheral nerves?
teased fiber preparations
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What do teased fiber preparations allow for?
examination of individual axons of peripheral nerves
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What is flanked by nodes of Ranvier?
a normal axon
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What is a normal axon with a long thick dark myelin internode flanked by?
nodes of ranvier with a long thick dark myelin internode
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How is a normal axon with a long thick dark myelin internode flanked?
by nodes of ranvier
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What shows a segment surrounded by a series of thinly myelinated internodes of uneven length flanked on both ends by normal thicker myelin internodes?
the right axon
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What does the right axon, by contrast, show?
a segment surrounded by a series of thinly myelinated internodes of uneven length flanked on both ends by normal thicker myelin internodes
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What share the same fiber type (fiber type grouping)?
large clusters of fibers
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Under what conditions do clusters of fibers appear that all share the same fiber type?
with ongoing denervation and reinnervation
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