siddharthtumre/jnlpba-split · Datasets at Hugging Face

id stringlengths 1 5	tokens list	ner_tags list
4984	[ "Indeed", ",", "monocytes", "pretreated", "with", "IL-10", "are", "able", "so", "inhibit", "NF-kappa", "B", "nuclear", "activity", "in", "purified", "T", "lymphocytes", "stimulated", "with", "OKT3", "." ]	[ 0, 0, 7, 0, 0, 9, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 7, 8, 0, 0, 9, 0 ]
5327	[ "In", "an", "attempt", "to", "identify", "changes", "in", "gene", "expression", "that", "accompany", "the", "T-cell", "stimulation", "defects", "associated", "with", "the", "loss", "of", "Rel", ",", "we", "have", "examined", "the", "expression", "of", "cell", ...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 7, 8, 8, 0 ]
15305	[ "Similarly", ",", "in", "transfection", "experiments", "in", "which", "the", "selective", "kappa", "B", "binding", "sites", "were", "used", "to", "drive", "the", "expression", "of", "a", "chloramphenicol", "acetyltransferase", "reporter", "construct", ",", "the", ...	[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 9, 10, 0, 0, 9, 10, 10, 10, 0, 9, 10, 10, 0, 0, 0, 0, 0, 0, 0, ...
11536	[ "The", "Bmax", "in", "these", "subjects", "significantly", "increased", "to", "6.61", "+/-", "2.02", "(", "257.7", "+/-", "107.8", "%", ")", "after", "24", "h", "stimulation", "with", "concanavalin", "A", "(", "p", "<", "0.01", ")", ",", "while", "the", ...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
9648	[ "The", "NH2Cl-treated", "neutrophils", "showed", "a", "decrease", "in", "both", "PKC", "activity", "and", "PMA-induced", "phosphorylation", "of", "a", "47-kDa", "protein", ",", "which", "corresponds", "to", "the", "cytosolic", "factor", "of", "NADPH", "oxidase", ...	[ 0, 5, 6, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 9, 10, 0, 9, 10, 0, 9, 10, 10, 10, 0 ]
17040	[ "The", "1", ",", "25", "(", "OH", ")", "2D3", "receptor", "of", "S-LB1", "was", "comparable", "to", "the", "well-characterized", "chick", "intestinal", "1", ",", "25", "(", "OH", ")", "2D3", "receptor", "in", "terms", "of", "its", "ligand", "binding", ...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 0, 0, 0, 0, 0, 9, 10, 10, 10, 10, 10, 10, 10, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
8778	[ "C-fos", "has", "been", "reported", "to", "be", "one", "of", "the", "immediate", "early", "genes", "in", "signal", "transduction", "systems", "after", "many", "kinds", "of", "stresses", ",", "including", "ionizing", "radiation", "." ]	[ 1, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
13767	[ "UT-7/GM", "was", "used", "as", "a", "model", "system", ",", "because", "this", "cell", "line", "can", "differentiate", "into", "erythroid-lineage", "cells", "with", "EPO", "treatment", "(", "Komatsu", "et", "al", ",", "Blood", "89", ":", "4021", ",", "199...	[ 5, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
15775	[ "During", "embryogenesis", ",", "the", "BSAP", "gene", "is", "transiently", "expressed", "in", "the", "mesencephalon", "and", "spinal", "cord", "with", "a", "spatial", "and", "temporal", "expression", "pattern", "that", "is", "distinct", "from", "that", "of", ...	[ 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
12724	[ "The", "class", "II", "transactivator", "(", "CIITA", ")", "is", "essential", "for", "the", "expression", "of", "major", "histocompatibility", "complex", "(", "MHC", ")", "class", "II", "antigens", "." ]	[ 0, 9, 10, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 10, 10, 10, 10, 10, 0 ]
17953	[ "The", "induction", "of", "Tax", "expression", "in", "JPX9", "cells", "resulted", "in", "about", "a", "twofold", "increase", "in", "the", "mRNA", "expression", "levels", "compared", "with", "the", "basal", "level", "." ]	[ 0, 0, 0, 9, 0, 0, 5, 6, 0, 0, 0, 0, 0, 0, 0, 0, 3, 0, 0, 0, 0, 0, 0, 0, 0 ]
9013	[ "This", "may", "explain", ",", "at", "least", "in", "part", ",", "the", "increased", "rate", "of", "HIV", "transmission", "in", "women", "with", "BV", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
10478	[ "Using", "a", "previously", "described", "mutant", "of", "the", "Jurkat", "T", "cell", "line", ",", "we", "show", "that", "proximal", "signaling", "events", "dependent", "on", "the", "presence", "of", "the", "CD45", "tyrosine", "phosphatase", "are", "required"...	[ 0, 0, 0, 0, 0, 0, 0, 5, 6, 6, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 9, 0, 9, 10, 0, 0 ]
323	[ "The", "inhibitory", "activity", "was", "heat", "labile", "and", "trypsin", "sensitive", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0 ]
1891	[ "In", "cells", "stimulated", "with", "anti-CD3", "mAb", ",", "PGE2", "inhibited", "cell", "proliferation", "and", "the", "production", "of", "all", "the", "cytokines", "examined", "." ]	[ 0, 0, 0, 0, 9, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0 ]
13547	[ "Qualitatively", "different", "effects", "were", "observed", "for", "the", "IL-1", "-induced", "activation", "of", "stress-activated", "protein", "(", "SAP", ")", "kinases", ":", "permanent", "overexpression", "of", "IRAK", "did", "not", "affect", "the", "dose", ...	[ 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 9, 10, 10, 10, 10, 10, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
379	[ "Finally", ",", "we", "show", "by", "both", "footprint", "analysis", "and", "functional", "assays", "that", "the", "ability", "of", "the", "G", "+", "C-rich", "region", "to", "increase", "alpha-globin", "promoter", "activity", "from", "a", "stably", "integrate...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 1, 2, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 1, 2, 2, 0, 0, 9, 10, 9, 0 ]
7167	[ "RESULTS", ":", "Therapeutic", "concentrations", "of", "As2O3", "(", "1-2", "microM", ")", "had", "dual", "effects", "on", "malignant", "lymphocytes", ":", "1", ")", "inhibition", "of", "growth", "through", "adenosine", "triphosphate", "(", "ATP", ")", "deplet...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
2060	[ "To", "define", "the", "mechanism", "of", "action", "of", "the", "Nef", "protein", ",", "the", "signal", "transduction", "pathways", "which", "may", "be", "affected", "in", "T", "cells", "by", "constitutive", "expression", "of", "the", "nef", "gene", "were",...	[ 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
11876	[ "Moreover", ",", "ACH-2", "cells", "treated", "with", "HOCl", "or", "H2O2", "released", "tumour", "necrosis", "factor-alpha", "(", "TNF-alpha", ")", "in", "the", "supernatants", "." ]	[ 0, 0, 5, 6, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 9, 0, 0, 0, 0, 0 ]
1886	[ "Anti-", "ZEBRA", "activity", "was", "not", "significantly", "increased", "in", "patients", "affected", "with", "ARNHL", ",", "the", "cells", "of", "which", "expressed", "replicative", "gene", "products", "(", "P", ">", "0.05", ")", "." ]	[ 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
10150	[ "The", "aim", "of", "the", "present", "study", "was", "to", "investigate", "whether", "glucocorticoids", "also", "regulate", "the", "expression", "of", "L-selectin", "and", "CD11/CD18", "integrins", "on", "human", "neutrophil", "granulocytes", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 9, 0, 7, 8, 8, 0 ]
14642	[ "Regulation", "of", "lymphoid-specific", "immunoglobulin", "mu", "heavy", "chain", "gene", "enhancer", "by", "ETS-domain", "proteins", "." ]	[ 0, 0, 1, 2, 2, 2, 2, 2, 2, 0, 0, 0, 0 ]
4005	[ "They", "are", "composed", "of", "different", "structural", "domains", ",", "including", "distinct", "domains", "for", "DNA", "and", "ligand", "binding", "." ]	[ 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
8706	[ "Here", "we", "demonstrate", "that", "fusion", "of", "HeLa", "cells", "with", "either", "diploid", "or", "tetraploid", "B", "cells", "(", "Daudi", ")", "results", "in", "widespread", "extinction", "of", "several", "other", "B", "cell-encoded", "genes", "that",...	[ 0, 0, 0, 0, 0, 0, 5, 6, 0, 0, 7, 8, 8, 8, 8, 0, 5, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
14148	[ "Negative", "transcriptional", "regulation", "of", "human", "interleukin", "2", "(", "IL-2", ")", "gene", "by", "glucocorticoids", "through", "interference", "with", "nuclear", "transcription", "factors", "AP-1", "and", "NF-AT", "." ]	[ 0, 0, 0, 0, 1, 2, 2, 2, 2, 2, 2, 0, 0, 0, 0, 0, 9, 10, 10, 9, 0, 9, 0 ]
6021	[ "When", "the", "same", "MTHC", "lines", "are", "exposed", "to", "TNF-alpha", "in", "combination", "with", "IFN-gamma", ",", "the", "cells", "instead", "become", "DC", "." ]	[ 0, 0, 0, 5, 6, 0, 0, 0, 9, 0, 0, 0, 9, 0, 0, 0, 0, 0, 7, 0 ]
15114	[ "High", "affinity", "aldosterone", "binding", "to", "plasma", "membrane", "rich", "fractions", "from", "mononuclear", "leukocytes", ":", "is", "there", "a", "membrane", "receptor", "for", "mineralocorticoids", "?" ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 9, 10, 0, 0, 0 ]
12799	[ "This", "region", "contains", "binding", "sites", "for", "several", "transcription", "factors", ",", "including", "the", "STAT", "family", "and", "NF-IL6", ",", "and", "the", "expression", "of", "LOX-1", "was", "upregulated", "by", "several", "cytokines", "." ]	[ 0, 0, 0, 1, 2, 0, 0, 9, 10, 0, 0, 0, 9, 10, 0, 9, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 9, 0 ]
6984	[ "All", "tissues", "and", "cells", "studied", "were", "homozygous", "for", "the", "wild-type", "gene", ",", "and", "were", "heterozygous", "as", "well", "as", "homozygous", "for", "the", "codon-10-variant", "type", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0 ]
15200	[ "We", "have", "shown", "that", "the", "Z", "gene", "product", ",", "which", "binds", "to", "AP-1", "sites", "as", "a", "homodimer", "and", "has", "sequence", "similarity", "to", "c-Fos", ",", "can", "efficiently", "activate", "the", "EBV", "early", "promot...	[ 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 1, 2, 2, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 0, 0, 5, 6, 0, 0 ]
5060	[ "Coexpression", "of", "the", "interleukin-13", "and", "interleukin-4", "genes", "correlates", "with", "their", "physical", "linkage", "in", "the", "cytokine", "gene", "cluster", "on", "human", "chromosome", "5q23-31", "." ]	[ 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 1, 2, 2, 0 ]
8652	[ "CD23", "expression", "and", "IgE", "synthesis", "by", "IL-4", "were", "augmented", "in", "Ile50-bearing", "PBMC", ",", "compared", "with", "those", "bearing", "Val50", "." ]	[ 9, 0, 0, 9, 0, 0, 9, 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 0, 0 ]
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3369	[ "We", "next", "studied", "p65", "and", "c-Rel", "protein", "expression", "in", "FDC", "clusters", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0, 0 ]
406	[ "Moreover", ",", "both", "the", "mutant", "nm23-H2His", "protein", "and", "truncated", "nm23-H2", "protein", "containing", "N-terminal", "(", "1-60", ")", "peptide", ",", "which", "do", "not", "have", "NDP", "kinase", "activity", ",", "also", "inhibited", "ery...	[ 0, 0, 0, 0, 9, 10, 10, 0, 9, 10, 10, 0, 9, 10, 10, 10, 10, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 5, 6, 0 ]
4416	[ "Taken", "together", ",", "these", "results", "support", "our", "conclusion", "that", "transcriptional", "transactivation", "is", "a", "necessary", "signaling", "component", "of", "S49", "cell", "apoptosis", ",", "although", "an", "additional", "role", "for", "GR"...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0 ]
4884	[ "Expression", "of", "p13MTCP1", "is", "restricted", "to", "mature", "T-cell", "proliferations", "with", "t", "(", "X", ";", "14", ")", "translocations", "." ]	[ 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
8081	[ "In", "AITL/GC", ",", "GCs", "were", "less", "dense", ",", "GC", "borders", "were", "ill", "defined", "and", "irregular", ",", "and", "the", "number", "of", "interfollicular", "Bcl-6+", "cells", "was", "markedly", "increased", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 0, 0, 0, 0 ]
17959	[ "Human", "herpesvirus", "6", ",", "a", "predominantly", "T", "lymphotropic", "virus", ",", "has", "been", "recently", "shown", "to", "infect", "some", "EBV-positive", "B", "cell", "lines", ",", "and", "to", "induce", "in", "them", "the", "activation", "of", ...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 6, 6, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
5477	[ "IL-10", "cooperates", "with", "TNF-alpha", "to", "activate", "HIV-1", "from", "latently", "and", "acutely", "infected", "cells", "of", "monocyte/macrophage", "lineage", "." ]	[ 9, 0, 0, 9, 0, 0, 0, 0, 7, 8, 8, 8, 8, 0, 7, 8, 0 ]
1327	[ "We", "propose", "the", "common", "pathway", "as", "the", "simplest", "way", "of", "accounting", "for", "the", "common", "requirements", "and", "properties", "of", "the", "signaling", "pathway", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
7083	[ "Fibroblast", "growth", "factor-1", "(", "FGF-1", ")", "enhances", "IL-2", "production", "and", "nuclear", "translocation", "of", "NF-kappaB", "in", "FGF", "receptor-bearing", "Jurkat", "T", "cells", "." ]	[ 9, 10, 10, 0, 9, 0, 0, 9, 0, 0, 0, 0, 0, 9, 0, 5, 6, 6, 6, 6, 0 ]
15690	[ "In", "addition", ",", "activation", "of", "c-raf", "kinase", "was", "normal", "." ]	[ 0, 0, 0, 0, 0, 9, 10, 0, 0, 0 ]
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9909	[ "NF-kappaB", ",", "which", "resides", "in", "an", "inactive", ",", "cytoplasmic", "complex", "in", "unstimulated", "cells", ",", "is", "activated", "by", "phosphorylation", "and", "degradation", "of", "its", "inhibitory", "subunit", ",", "IkappaB", "." ]	[ 9, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 5, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 9, 0 ]
4436	[ "IL-2", "induced", "less", "STAT1", "alpha", "activation", "and", "IFN-alpha", "induced", "greater", "STAT5", "activation", "in", "NK3.3", "cells", "compared", "with", "preactivated", "primary", "NK", "cells", "." ]	[ 9, 0, 0, 9, 10, 0, 0, 9, 0, 0, 9, 0, 0, 5, 6, 0, 0, 5, 6, 6, 6, 0 ]
1854	[ "By", "contrast", ",", "the", "MAP", "kinases", "ERK1", "and", "ERK2", "were", "fully", "activated", "by", "TPA", "or", "TCR", "stimulation", "and", "were", "not", "affected", "by", "Ca2+", ",", "CD28", ",", "or", "CsA", "." ]	[ 0, 0, 0, 0, 9, 10, 9, 0, 9, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
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9890	[ "Transcription", "factor", "NF-kappaB", "regulates", "inducible", "Oct-2", "gene", "expression", "in", "precursor", "B", "lymphocytes", "." ]	[ 9, 10, 9, 0, 0, 1, 2, 0, 0, 7, 8, 8, 0 ]
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4984

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5327

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15305

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11536

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9648

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