Datasets:
siddharthtumre
/
Revised-JNLPBA

Dataset card Data Studio Files
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1
id
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1
5
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5501
[ "We", "used", "histochemical", "markers", "to", "define", "the", "immunophenotype", "of", "43", "IDCs", "with", "respect", "to", "comedo", "versus", "noncomedo", "status", "and", "patterns", "of", "angiogenesis", "." ]
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5502
[ "RESULTS", "--", "Reactions", "in", "comedo", "carcinomas", "were", "significantly", "negative", "for", "estrogen", "receptor", "and", "progesterone", "receptor", ",", "and", "positive", "for", "p53", "and", "HER-2/neu", "more", "often", "than", "the", "noncomedo"...
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5503
[ "All", "seven", "IDCs", "associated", "with", "Paget", "'s", "disease", "showed", "positive", "reactions", "for", "HER-2/neu", "." ]
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5504
[ "Basement", "membrane", "immunoreactivity", "for", "type", "IV", "collagen", "and", "laminin", "was", "discontinuous", "in", "most", "examples", "of", "IDC", "regardless", "of", "type", ",", "with", "a", "trend", "toward", "more", "intense", "staining", "in", ...
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5505
[ "Periductal", "angiogenesis", "was", "not", "significantly", "related", "to", "the", "type", "of", "IDC", "but", "was", "more", "pronounced", "with", "comedo", "carcinomas", "." ]
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5506
[ "CONCLUSIONS", "--", "These", "observations", "indicate", "that", "there", "are", "immunophenotypic", "correlates", "to", "the", "current", "structural", "classification", "of", "IDC", "." ]
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5507
[ "The", "immunophenotype", "of", "IDC", "is", "helpful", "in", "subclassifying", "an", "IDC", "and", "could", "prove", "useful", "as", "a", "prognostic", "indicator", "for", "local", "control", "in", "patients", "treated", "by", "breast-conserving", "therapy", "....
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5508
[ "Inhibition", "of", "protein", "phosphatase", "2A", "induces", "serine/threonine", "phosphorylation", ",", "subcellular", "redistribution", ",", "and", "functional", "inhibition", "of", "STAT3", "." ]
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5509
[ "Signal", "transducers", "and", "activators", "of", "transcription", "(", "STATs", ")", "are", "rapidly", "phosphorylated", "on", "tyrosine", "residues", "in", "response", "to", "cytokine", "and", "growth", "factor", "stimulation", "of", "cell", "surface", "recept...
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5510
[ "STATs", "hereafter", "are", "translocated", "to", "the", "nucleus", "where", "they", "act", "as", "transcription", "factors", "." ]
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5511
[ "Recent", "reports", "suggest", "that", "serine", "phosphorylation", "of", "STATs", "also", "is", "involved", "in", "the", "regulation", "of", "STAT", "-mediated", "gene", "transcription", "." ]
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5512
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5513
[ "We", "show", "that", "an", "inhibitor", "of", "protein", "phosphatases", "(", "PPs", ")", "PP1/PP2A", ",", "calyculin", "A", ",", "induces", "(", "i", ")", "phosphorylation", "of", "STAT3", "on", "serine", "and", "threonine", "residues", ",", "(", "ii", ...
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5514
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5515
[ "Pretreatment", "with", "the", "broad", "serine/threonine", "kinase", "inhibitor", "staurosporine", "partly", "blocked", "the", "calyculin", "A", "-induced", "STAT3", "phosphorylation", ",", "whereas", "inhibitors", "of", "serine/threonine", "kinases", ",", "such", "a...
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5516
[ "In", "conclusion", ",", "we", "provide", "evidence", "that", "PP2A", "plays", "a", "crucial", "role", "in", "the", "regulation", "of", "STAT3", "phosphorylation", "and", "subcellular", "distribution", "in", "T", "cells", "." ]
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5517
[ "Moreover", ",", "our", "findings", "suggest", "that", "the", "level", "of", "STAT3", "phosphorylation", "is", "balanced", "between", "a", "staurosporine-sensitive", "kinase", "(", "s", ")", "and", "PP2A", "." ]
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5518
[ "Polyamines", "in", "human", "breast", "cancer", "and", "its", "relations", "to", "classical", "prognostic", "features", ":", "clinical", "implications", "." ]
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5519
[ "Experimental", "evidence", "suggest", "an", "important", "role", "of", "polyamines", "in", "breast", "cancer", "development", "." ]
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5520
[ "Polyamines", "have", "been", "determined", "in", "tissue", "and", "erythrocyte", "samples", "from", "100", "patients", "with", "primary", "invasive", "breast", "cancer", "and", "30", "patients", "with", "fibroadenomas", "." ]
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5521
[ "Statistical", "analysis", "was", "performed", "in", "order", "to", "determine", "the", "prognostic", "value", "of", "the", "polyamine", "patterns", "of", "tumor", "tissues", "and", "erythrocytes", "in", "comparison", "with", "clinical", "and", "histological", "pr...
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5522
[ "In", "malignant", "tissues", ",", "polyamine", "levels", "were", "significantly", "higher", "than", "in", "benign", "tissues", "." ]
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5523
[ "They", "correlated", "with", "markers", "of", "tumor", "aggressivity", "(", "axillary", "node", "involvement", "and", "especially", "with", "markers", "of", "high", "mitotic", "rate", "as", "Ki-67", "staining", ",", "histological", "grade", ")", "." ]
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5524
[ "No", "correlation", "was", "found", "between", "estrogen", "and", "progesterone", "status", ",", "tumor", "size", "and", "polyamine", "concentrations", "." ]
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5525
[ "Erythrocyte", "polyamines", "levels", "were", "identical", "between", "cancer", "patients", "and", "controls", "." ]
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5526
[ "The", "knowledge", "of", "the", "polyamine", "pattern", "in", "breast", "cancer", "could", "become", "useful", "in", "clinical", "practice", "particularly", "if", "polyamine", "metabolism", "is", "targeted", "as", "a", "therapeutic", "approach", "." ]
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5527
[ "Signal", "transduction", "pathways", "triggered", "by", "the", "FcepsilonRIIb", "receptor", "(", "CD23", ")", "in", "human", "monocytes", "lead", "to", "nuclear", "factor-kappaB", "activation", "." ]
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5528
[ "BACKGROUND", ":", "Alveolar", "macrophages", "play", "a", "key", "role", "in", "the", "initiation", "of", "the", "inflammatory", "reaction", "of", "allergic", "asthma", "." ]
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5529
[ "Alveolar", "macrophages", "and", "peripheral", "blood", "monocytes", "are", "activated", "when", "IgE/allergen", "immune", "complexes", "bind", "to", "the", "CD23", "receptor", ",", "which", "leads", "to", "the", "production", "of", "inflammatory", "cytokines", "...
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5530
[ "OBJECTIVE", ":", "We", "sought", "to", "investigate", "the", "molecular", "mechanisms", "regulating", "this", "early", "inflammatory", "response", "." ]
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5531
[ "We", "have", "focused", "on", "the", "study", "of", "the", "signal", "transduction", "pathways", "triggered", "by", "CD23", "in", "human", "monocytes", "and", "the", "promonocytic", "cell", "line", "U937", "." ]
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5532
[ "METHODS", ":", "CD23", "was", "cross-linked", "in", "human", "monocytes", "and", "U937", "cells", "with", "IgE", "immune", "complexes", "." ]
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5533
[ "Surface", "expression", "of", "CD23", "was", "determined", "by", "FACS", "analysis", "." ]
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5534
[ "Transcription", "factor", "activation", "and", "gene", "transcription", "were", "studied", "by", "gel-shift", "assays", "and", "Northern", "blot", "analysis", ",", "respectively", "." ]
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5535
[ "IkappaBalpha", "phosphorylation", "and", "degradation", "was", "analyzed", "by", "Western", "blot", "." ]
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5536
[ "RESULTS", ":", "Nuclear", "factor", "(", "NF", ")", "-kappaB", "is", "the", "main", "transcription", "factor", "involved", "in", "the", "gene", "activation", "that", "follows", "CD23", "cross-linking", "in", "monocytes", "." ]
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5537
[ "CD23-induced", "NF-kappaB", "is", "a", "heterodimer", "composed", "of", "p65/p50", "subunits", "." ]
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5538
[ "NF-kappaB", "nuclear", "translocation", "is", "secondary", "to", "the", "phosphorylation", "and", "subsequent", "degradation", "of", "the", "NF-kappaB", "inhibitory", "molecule", "IkappaBalpha", "." ]
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5539
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5540
[ "IkappaBalpha", "degradation", "and", "NF-kappaB", "nuclear", "translocation", "correlate", "with", "transcriptional", "activation", "of", "the", "inflammatory", "cytokines", "TNF-alpha", "and", "IL-1beta", "." ]
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5541
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5542
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5543
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5544
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5545
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5546
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5547
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5548
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5549
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5550
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5551
[ "Copyright", "1999", "Wiley-Liss", ",", "Inc", "." ]
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5552
[ "Bcl-2", "-mediated", "drug", "resistance", ":", "inhibition", "of", "apoptosis", "by", "blocking", "nuclear", "factor", "of", "activated", "T", "lymphocytes", "(", "NFAT", ")", "-induced", "Fas", "ligand", "transcription", "." ]
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5553
[ "Bcl-2", "inhibits", "apoptosis", "induced", "by", "a", "variety", "of", "stimuli", ",", "including", "chemotherapy", "drugs", "and", "glucocorticoids", "." ]
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5554
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5555
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5556
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5557
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5558
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5559
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5560
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5561
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5562
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5563
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5564
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