siddharthtumre/Revised-JNLPBA · Datasets at Hugging Face

id stringlengths 1 5	tokens list	ner_tags list
4601	[ "Inhibition", "by", "IL-10", "of", "proinflammatory", "cytokine", "release", "appears", "to", "occur", "at", "the", "level", "of", "gene", "transcription", "for", "TNF-alpha", "and", "both", "transcriptionally", "and", "posttranscriptionally", "for", "IL-1beta", "."...	[ 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 9, 0 ]
4602	[ "Characterization", "and", "purification", "of", "a", "protein", "kinase", "C", "substrate", "in", "human", "B", "cells", "." ]	[ 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 7, 8, 8, 0 ]
4603	[ "Identification", "as", "lymphocyte-specific", "protein", "1", "(", "LSP1", ")", "." ]	[ 0, 0, 9, 10, 10, 0, 9, 0, 0 ]
4604	[ "Incubation", "of", "B-chronic", "lymphocytic", "leukemia", "(", "B-CLL", ")", "cells", "with", "phorbol", "esters", "resulted", "in", "the", "phosphorylation", "of", "two", "major", "PKC", "substrates", ",", "MARCKS", "(", "myristoylated", ",", "alanine-rich", ...	[ 0, 0, 7, 8, 8, 8, 8, 8, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 9, 0, 9, 10, 10, 10, 10, 10, 0, 0, 9, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, ...
4605	[ "p60", "phosphorylation", "was", "time", "and", "PMA", "dose", "dependent", ",", "and", "was", "induced", "by", "cell-permeable", "diacylglycerol", ",", "but", "not", "by", "inactive", "phorbol", "esters", "." ]	[ 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4606	[ "Two-dimensional", "electrophoretic", "analysis", "of", "the", "protein", "phosphorylation", "pattern", "from", "the", "B", "cell", "line", "CESS", "demonstrated", "the", "identity", "between", "the", "p60", "protein", "expressed", "in", "this", "cell", "line", "a...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 6, 6, 6, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0 ]
4607	[ "p60", "was", "purified", "from", "CESS", "cells", "and", "peptide", "microsequencing", "of", "this", "protein", "revealed", "that", "it", "was", "lymphocyte-specific", "protein", "1", "(", "LSP1", ")", ",", "that", "is", "here", "characterized", "as", "the", ...	[ 9, 0, 0, 0, 5, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 7, 8, 0 ]
4608	[ "Transcription", "factors", "of", "T", "and", "B", "lymphocytes", "--", "basic", "research", "and", "clinical", "perspectives", "for", "gastroenterology", "." ]	[ 0, 0, 0, 7, 8, 8, 8, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4609	[ "Tissue", "specific", "regulation", "of", "gene", "expression", "by", "transcription", "factors", "is", "a", "fascinating", "new", "field", "in", "molecular", "immunology", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4610	[ "This", "review", "summarizes", "data", "on", "specific", "regulation", "of", "promoters", "and", "enhancers", "by", "nuclear", "trans-acting", "factors", "in", "lymphocytes", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0 ]
4611	[ "The", "structural", "classes", "of", "transcription", "factors", "are", "described", "and", "basic", "methods", "for", "detection", "and", "analysis", "of", "transcription", "factors", "are", "detailed", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4612	[ "Furthermore", ",", "the", "most", "important", "trans-acting", "factors", "of", "T", "and", "B", "lymphocytes", "(", "e.g", ".", "NF-kB", ",", "NF-AT", "and", "STAT", "families", ")", "and", "their", "functional", "importance", "are", "described", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 8, 0, 0, 0, 9, 0, 9, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0 ]
4613	[ "Several", "methods", "for", "specific", "down-regulation", "of", "transcription", "factors", "are", "shown", "that", "may", "be", "relevant", "to", "treatment", "of", "human", "disease", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4614	[ "The", "data", "are", "discussed", "with", "regard", "to", "their", "potential", "clinical", "relevance", "for", "gastroenterology", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4615	[ "Selective", "effects", "of", "DNA", "damaging", "agents", "on", "HIV", "long", "terminal", "repeat", "activation", "and", "virus", "replication", "in", "vitro", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0 ]
4616	[ "Much", "attention", "has", "recently", "focused", "on", "the", "observation", "that", "UV", "light", "can", "activate", "the", "long", "terminal", "repeat", "(", "LTR", ")", "of", "the", "human", "immunodeficiency", "virus", "(", "HIV", ")", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4617	[ "Although", "the", "mechanism", "of", "LTR", "activation", "remains", "obscure", ",", "several", "lines", "of", "investigation", "have", "suggested", "that", "it", "is", "a", "result", "of", "activation", "of", "the", "NF-kappa", "B", "transcription", "factor", ...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4618	[ "In", "this", "report", ",", "we", "present", "data", "demonstrating", "that", "HIV", "LTR", "activation", "is", "not", "a", "general", "consequence", "of", "cellular", "DNA", "damage", ",", "but", "rather", "a", "process", "unique", "to", "specific", "genot...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0 ]
4619	[ "Furthermore", ",", "we", "demonstrate", "that", "several", "of", "these", "agents", "can", "significantly", "increase", "HIV", "replication", "and", "accelerate", "CD4", "-positive", "lymphocyte", "cytotoxicity", "in", "vitro", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0, 0, 0, 0 ]
4620	[ "These", "findings", ",", "therefore", ",", "could", "have", "clinical", "significance", "to", "AIDS", "patients", "with", "malignancies", "who", "are", "undergoing", "radiotherapy", "and", "chemotherapy", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4621	[ "Receptors", "for", "interleukin", "(", "IL", ")", "-10", "and", "IL-6-type", "cytokines", "use", "similar", "signaling", "mechanisms", "for", "inducing", "transcription", "through", "IL-6", "response", "elements", "." ]	[ 0, 0, 9, 10, 10, 10, 10, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0 ]
4622	[ "The", "cytoplasmic", "domain", "of", "the", "receptor", "for", "interleukin", "10", "(", "IL-10R", ")", "contains", "two", "box", "3", "sequence", "motifs", "that", "have", "been", "identified", "in", "the", "signal-transducing", "receptor", "subunits", "for", ...	[ 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 1, 2, 0 ]
4623	[ "To", "determine", "whether", "the", "IL-10R", "has", "signaling", "functions", "similar", "to", "IL-6R", "in", "cells", "normally", "expressing", "these", "receptors", ",", "leukocytes", "of", "the", "B-", ",", "T-", ",", "and", "NK-cell", "lineages", "were",...	[ 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 7, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 0 ]
4624	[ "Both", "cytokines", "activated", "factors", "that", "bound", "to", "the", "sis-inducible", "element", "and", "included", "STAT1", "and", "STAT3", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0 ]
4625	[ "The", "cell", "response", "to", "IL-10", "characteristically", "differed", "from", "that", "to", "IL-2/IL-15", ",", "IL-4", ",", "and", "interferon", "gamma", "." ]	[ 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 9, 10, 0 ]
4626	[ "The", "signaling", "capabilities", "of", "the", "IL-10R", "for", "activating", "specific", "STAT", "proteins", "and", "inducing", "gene", "transcription", "were", "defined", "by", "reconstitution", "of", "receptor", "functions", "in", "transfected", "tissue", "cult...	[ 0, 0, 0, 0, 0, 9, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4627	[ "COS-1", "cells", ",", "co-expressing", "the", "human", "IL-10R", "and", "individual", "STAT", "proteins", ",", "confirmed", "a", "preference", "of", "the", "IL-10R", "for", "STAT3", "and", "STAT1", "." ]	[ 5, 6, 0, 0, 0, 0, 9, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 9, 0 ]
4628	[ "Unlike", "many", "hematopoietin", "receptors", ",", "the", "IL-10R", "did", "not", "detectably", "activate", "STAT5", "." ]	[ 0, 0, 9, 10, 0, 0, 9, 0, 0, 0, 0, 9, 0 ]
4629	[ "The", "IL-10R", ",", "together", "with", "reporter", "gene", "constructs", "containing", "different", "IL-6-responsive", "gene", "elements", ",", "reconstituted", "in", "hepatoma", "cells", "an", "induction", "of", "transcription", "by", "IL-10", "that", "was", "...	[ 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 9, 0 ]
4630	[ "This", "regulation", "could", "not", "be", "appreciably", "modified", "by", "enhanced", "expression", "of", "STAT", "proteins", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0 ]
4631	[ "The", "similar", "actions", "of", "IL-10R", "and", "IL-6R", "on", "the", "induction", "of", "endogenous", "IL-6-responsive", "genes", "were", "demonstrated", "in", "hepatoma", "cells", "stably", "expressing", "the", "IL-10R", "." ]	[ 0, 0, 0, 0, 9, 0, 9, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 7, 8, 0, 0, 0, 9, 0 ]
4632	[ "These", "receptor", "functions", "required", "the", "presence", "of", "the", "box", "3", "motifs", ",", "as", "shown", "by", "the", "analysis", "of", "the", "mouse", "IL-10R", "constructs", "containing", "progressively", "truncated", "cytoplasmic", "domains", "...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0 ]
4633	[ "The", "data", "demonstrate", "that", "the", "IL-10R", ",", "unlike", "other", "members", "of", "the", "interferon", "receptor", "family", ",", "is", "highly", "effective", "in", "recruiting", "the", "signaling", "pathways", "of", "IL-6-type", "cytokine", "recep...	[ 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0 ]
4634	[ "Induction", "of", "CIITA", "and", "modification", "of", "in", "vivo", "HLA-DR", "promoter", "occupancy", "in", "normal", "thymic", "epithelial", "cells", "treated", "with", "IFN-gamma", ":", "similarities", "and", "distinctions", "with", "respect", "to", "HLA-DR-...	[ 0, 0, 9, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 7, 8, 8, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0 ]
4635	[ "In", "this", "study", ",", "the", "IFN-gamma", "induction", "of", "MHC", "class", "II", "gene", "expression", "in", "primary", "cultures", "of", "thymic", "epithelial", "cells", "(", "TEC", ")", "was", "analyzed", "." ]	[ 0, 0, 0, 0, 0, 9, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 7, 8, 8, 0, 7, 0, 0, 0, 0 ]
4636	[ "This", "cellular", "system", "offers", "the", "advantage", "that", "MHC", "class", "II", "induction", "is", "studied", "in", "a", "``", "physiologic", "''", "cell", "lineage", "that", ",", "as", "a", "result", "of", "this", "expression", "within", "the", ...	[ 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0 ]
4637	[ "It", "was", "found", "that", "the", "MHC", "class", "II", "gene", "expression", "was", "associated", "with", "the", "de", "novo", "transcription", "of", "the", "gene", "encoding", "the", "CIITA", "trans-activator", ",", "a", "crucial", "MHC", "class", "II",...	[ 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 9, 10, 10, 10, 10, 10, 0 ]
4638	[ "Furthermore", ",", "the", "anatomy", "of", "interaction", "between", "the", "MHC", "class", "II", "DRA", "promoter", "and", "corresponding", "binding", "factors", "was", "analyzed", "by", "in", "vivo", "DNAse", "I", "footprint", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0 ]
4639	[ "It", "was", "found", "that", "treatment", "with", "IFN-gamma", "induces", "changes", "in", "the", "occupancy", "of", "the", "DRA", "gene", "regulatory", "sequences", "by", "nuclear", "factors", "." ]	[ 0, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0 ]
4640	[ "The", "resulting", "occupancy", "displays", "strong", "similarities", "with", "the", "one", "observed", "in", "the", "MHC", "class", "II-constitutive", "B", "cells", ",", "represented", "by", "both", "the", "Burkitt", "lymphoma", "line", "Raji", "and", "normal"...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0, 0, 0, 0, 0, 5, 6, 6, 6, 0, 0, 0, 0, 7, 8, 0 ]
4641	[ "However", ",", "some", "peculiar", "differences", "were", "observed", "between", "the", "TEC", ",", "either", "IFN-gamma", "-induced", "or", "not", ",", "and", "the", "constitutive", "B", "cells", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 7, 0, 0, 9, 0, 0, 0, 0, 0, 0, 0, 7, 8, 0 ]
4642	[ "These", "results", "suggest", "that", "both", "common", "mechanisms", ",", "such", "as", "the", "one", "mediated", "by", "the", "CIITA", "trans-activator", ",", "and", "distinct", "tissue-specific", "constraints", "contribute", "to", "the", "transcriptional", "co...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 1, 2, 2, 2, 0, 0 ]
4643	[ "Inhibitory", "effect", "of", "E3330", ",", "a", "novel", "quinone", "derivative", "able", "to", "suppress", "tumor", "necrosis", "factor-alpha", "generation", ",", "on", "activation", "of", "nuclear", "factor-kappa", "B", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 0, 9, 10, 10, 0 ]
4644	[ "(", "2E", ")", "-3-", "[", "5-", "(", "2", ",", "3-Dimethoxy-6-methyl-1", ",", "4-benzoquinoyl", ")", "]", "-2-nonyl-2-", "propenoic", "acid", "(", "E3330", ")", ",", "is", "a", "novel", "agent", "with", "hepatoprotective", "activity", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4645	[ "We", "report", "the", "effect", "of", "E3330", "on", "transcriptional", "activation", "of", "tumor", "necrosis", "factor", "(", "TNF", ")", "-alpha", "gene", "and", "on", "nuclear", "factor", "(", "NF", ")", "-kappa", "B", "activation", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 2, 2, 2, 0, 0, 9, 10, 10, 10, 10, 10, 10, 0, 0 ]
4646	[ "Nuclear", "run-on", "experiments", "showed", "that", "E3330", "decreases", "transcriptional", "activation", "of", "TNF-alpha", "gene", "induced", "by", "lipopolysaccharide", "(", "LPS", ")", "stimulation", "in", "human", "peripheral", "monocytes", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 7, 8, 8, 0 ]
4647	[ "To", "investigate", "the", "inhibitory", "mechanisms", ",", "we", "constructed", "a", "secreted-type", "placental", "alkaline", "phosphatase", "(", "PLAP", ")", "reporter", "gene", "whose", "transcription", "is", "controlled", "by", "a", "1.4-kb", "human", "TNF-a...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 2, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0 ]
4648	[ "A", "stable", "transformant", "of", "the", "PLAP", "reporter", "gene", "derived", "from", "human", "monocytic", "cell", "line", "showed", "very", "little", "activity", "on", "the", "promoter", "before", "stimulation", ",", "whereas", "LPS", "stimulation", "led"...	[ 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 5, 6, 6, 6, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 0 ]
4649	[ "E3330", "inhibited", "this", "induced", "promoter", "activity", "in", "a", "dose-dependent", "manner", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
4650	[ "There", "are", "four", "putative", "NF-kappa", "B", "binding", "sites", "(", "kappa", "B-1", ",", "kappa", "B-2", ",", "kappa", "B-3", ",", "kappa", "B-4", ")", "in", "human", "TNF-alpha", "promoter", "." ]	[ 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0 ]
4651	[ "By", "using", "mutated", "promoter-PLAP", "plasmids", ",", "we", "established", "that", "these", "NF-kappa", "B", "sites", "were", "necessary", "for", "induction", "of", "TNF-alpha", "transcription", "on", "stimulation", "with", "LPS", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 2, 0, 0, 0, 0, 0, 9, 0, 0, 0, 0, 0, 0 ]
4652	[ "A", "gel", "retardation", "experiment", "with", "synthetic", "double-stranded", "oligonucleotides", "showed", "that", "activated", "NF-kappa", "B", "consisting", "of", "p50/p65", "heterodimer", "bound", "to", "all", "four", "putative", "NF-kappa", "B", "DNA", "prob...	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 9, 10, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 0, 1, 2, 2, 2, 0, 0, 0, 0, 0, 0, 9, 0, 0 ]
4653	[ "E3330", "decreased", "activated", "NF-kappa", "B", "in", "nuclei", ",", "suggesting", "that", "E3330", "inhibits", "NF-kappa", "B", "activation", "and/or", "translocation", "of", "the", "nuclei", "." ]	[ 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 0, 0, 0, 0 ]
4654	[ "Western", "blotting", "analysis", "with", "anti-I", "kappa", "B-alpha", "antibody", "indicated", "that", "E3330", "inhibited", "degradation", "of", "I", "kappa", "B-alpha", ",", "which", "is", "an", "inhibitory", "protein", "of", "NF-kappa", "B", ",", "in", "...	[ 0, 0, 0, 0, 9, 10, 10, 10, 0, 0, 0, 0, 0, 0, 9, 10, 10, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0, 0, 0, 7, 0 ]
4655	[ "E3330", "may", "suppress", "the", "production", "of", "active", "oxygen", "species", "serving", "as", "common", "messengers", "to", "activate", "NF-kappa", "B", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 10, 0 ]
4656	[ "C-terminal", "activating", "and", "inhibitory", "domains", "determine", "the", "transactivation", "potential", "of", "BSAP", "(", "Pax-5", ")", ",", "Pax-2", "and", "Pax-8", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0, 9, 0, 0, 9, 0, 9, 0 ]
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4658	[ "In", "this", "study", "we", "have", "analysed", "the", "structural", "requirements", "for", "transcriptional", "activation", "by", "BSAP", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 9, 0 ]
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4669	[ "The", "ability", "to", "regulate", "AR", "gene", "transcription", "via", "the", "second", "messenger", "pathway", "is", "lost", "in", "the", "PC-3", "and", "DU-145", "cell", "lines", "." ]	[ 0, 0, 0, 0, 1, 2, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 5, 0, 5, 6, 6, 0 ]
4670	[ "This", "may", "be", "an", "important", "primary", "mechanism", "of", "androgen", "insensitivity", "in", "prostate", "cancer", "." ]	[ 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0 ]
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4601

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4602

[ "Characterization", "and", "purification", "of", "a", "protein", "kinase", "C", "substrate", "in", "human", "B", "cells", "." ]

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4603

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4604

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4605

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4610

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4624

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4630

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4633

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4636

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4637

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4638

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4640

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4641

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4642

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4643

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4644

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4645

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4647

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4648

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4649

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4650

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4660

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4669

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4670

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4671

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4673

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4674

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4677

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4678

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4680

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4681

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4682

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4683

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4685

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4688

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4689

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4692

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4693

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4696

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4698

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4699

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4700

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