Molecule name
stringlengths
12
12
SMILES
stringlengths
30
101
LogD
float64
-0.7
4.5
ASAP-0022474
NCC1=CC=CC(NC(=O)C2=CC=CN3C=C(CN4CCCC4)N=C23)=C1
0.2
ASAP-0021312
CN(C)C(=O)C1=NOC(CCCOC2=CC=C3C(OCC4CC4)=NOC3=C2)=C1
3.7
ASAP-0021658
CCOC1=NOC2=CC(OCCCC3=CC(C(=O)N(C)C)=NO3)=CC=C12
3.5
ASAP-0021134
CCOC1=NOC2=C(C)C(OCCCC3=CC(C(=O)N(C)C)=NO3)=CC=C12
4
ASAP-0021262
CCOC1=NOC2=CC(OCCCC3=CC(C(=O)N(C)C)=NO3)=C(C)C=C12
4
ASAP-0021070
C#CCCC1=CC=C(OCCCC2=CC(C(=O)N(C)C)=NO2)C=C1
3.5
ASAP-0020849
NCC1=CC=CC(NC(=O)C2=CC(Cl)=CC(CN)=C2)=C1
-0.6
ASAP-0020936
CN(C)C(=O)C1=NOC(CCCOC2=CC=CC(F)=C2)=C1
2.7
ASAP-0020930
O=C1NC(=O)[C@H](CC2=NC3=C(COCC3)S2)C2=CC=CC=C12
0.6
ASAP-0020875
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1COCCC1=CC(C(=O)N(C)C)=NO1
3.5
ASAP-0020904
C#CCCCCC1=CC=C(OCCCC2=CC(C(=O)N(C)C)=NO2)C=C1
4.4
ASAP-0020843
CN(C)C(=O)C1=NOC(CCCOC2=CC=C(F)C=C2)=C1
2.6
ASAP-0020827
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1OCCCC1=NC(C2=CC=NC=C2)=NO1
4.5
ASAP-0020873
CN(C)C(=O)C1=NOC(CCCOC2=CC=C(C3=NOC(C4CC4)=N3)C=C2)=C1
3.6
ASAP-0020818
CN(C)C(=O)C1=NOC(CCCOC2=CC=C(CCC3CCNCC3)C=C2)=C1
0.5
ASAP-0020915
O=C(NC1=CC(Cl)=CC(C(=O)NC2=CC=C3CNCC3=C2)=C1)OCC1=CC=CC=C1
2.8
ASAP-0017673
O=C(O)C1=CC(Cl)=CC=C1S(=O)(=O)NC1CCN(C2=NC(C3CC3)=CC(C(F)(F)F)=N2)CC1
2.8
ASAP-0017614
CC1=NN=C(CCCOC2=CC=C(C3=NOC(C(F)(F)F)=N3)C=C2C)N1
4.1
ASAP-0017652
CN(C)C(=O)C1=NOC(CCCN2C=CC3=NC(C4=NOC(C(F)(F)F)=N4)=CC=C32)=C1
2.7
ASAP-0017692
NCCC1=CC=C(NC(=O)C2=CC(Cl)=CC(NC(=O)OCC3=CC=CC=C3)=C2)C=C1
2.9
ASAP-0017520
CC1=CC(OCC2=CC=CC=C2)=CC=C1NS(=O)(=O)C1=CC=C(Cl)C=C1C(=O)O
2.7
ASAP-0017501
CCOC1=CC=CC(C2=CC=C(S(=O)(=O)NC3=CC=C(Cl)C=C3C(=O)O)C=C2)=C1
2.8
ASAP-0017573
O=C(O)C1=CC(Cl)=CC=C1NS(=O)(=O)C1=CC=C(C2=CC=CC=C2Cl)C=C1
3.6
ASAP-0017585
O=C(O)C1=CC(Cl)=C(F)C=C1S(=O)(=O)NC1=CC=C(OC2=CC=CC=C2Cl)C=C1
3.3
ASAP-0017436
CCOC1=NOC2=CC(OCCC3CCN(C4=CC=C(C)N=N4)CC3)=CC=C12
3
ASAP-0017440
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1OCCCC1=NN=CO1
4
ASAP-0017437
CN(C)C(=O)C1=NOC(CCCOC2=CC=C3CCCCC3=C2F)=C1
4.2
ASAP-0017441
CCOC(=O)C1=CC=C(OCCC2CCN(C3=CC=C(C)N=N3)CC2)C=C1
4.1
ASAP-0017292
CC1=NN=C(CCCOC2=CC=C(C3=NOC(C(F)(F)F)=N3)C=C2C)O1
4.4
ASAP-0017303
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1OCCCC1=CC(C(=O)N2CC[C@](C)(O)C2)=NO1
4.4
ASAP-0017302
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1OCCCC1=CC(C(=O)N2CC[C@@H](O)C2)=NO1
4.4
ASAP-0017297
CN(C)C(=O)C1=NOC(CCCN2N=CC3=CC(C4=NOC(C(F)(F)F)=N4)=CC=C32)=C1
3.6
ASAP-0017285
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1OCCCC1=CNN=C1
4
ASAP-0017296
CC1=NC(C2=CC=C(OCCCCCN3CCN(C4=CC=NC(N)=C4)C3=O)C=C2)=NO1
2.5
ASAP-0017289
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1OCCCC1=CN(C)N=C1
4.2
ASAP-0017298
CCON=CC1=CC=C(OCCC2CCN(C3=CC=C(C)N=N3)CC2)C=C1
4.4
ASAP-0017309
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1CCOCC1=CC(C(=O)N(C)C)=NO1
4
ASAP-0017305
CC1=CC(C2=NOC(C(F)(F)F)=N2)=CC=C1OCCCC1=CC(C(=O)N2CC[C@H](O)C2)=NO1
4.4
ASAP-0017037
O=C1NC(=O)[C@@H](CC2=CC=C3OCOC3=C2)C2=CC=CC=C12
2.4
ASAP-0016784
NCC1=CC=CC(NC(=O)C2=CC(OCC3=CC=CC=C3)=CC=C2CNC(=O)OCC2=CC=CC=C2)=C1
2.8
ASAP-0016778
NCC1=CC=CC(NC(=O)CN(C(=O)OCC2=CC=CC=C2)C2=CC=C(OCC3=CC=CC=C3)C=C2)=C1
2.9
ASAP-0016806
NCC1=CC=CC(NC(=O)C2=CC(Cl)=CC(NC(=O)OCC3=CC=CC=C3)=C2)=C1
2.7
ASAP-0016485
O=C(CC1=CNN=C1)NC1=CNC(=O)C2=CC=CC=C12
0.1
ASAP-0016445
CC1=CC(NC(=O)NC2=CNC(=O)C3=CC=C(F)C=C23)=NO1
1.9
ASAP-0016386
NCC1=CC=CC(CNC(=O)[C@H](NC(=O)OCC2=CC=CC=C2)C2=CC=C(OCC3=CC=CC=C3)C=C2)=C1
2.7
ASAP-0016242
NCC1=CC=CC(NC(=O)[C@H](NC(=O)OCC2=CC=CC=C2)C(C2CCC2)C2CCC2)=C1
2.5
ASAP-0016164
COC1=CC=C(CNC(=O)NC2=CNC(=O)C3=CC=NC=C23)C=N1
0.7
ASAP-0016130
O=C(NCC1=CC=CC=N1)NC1=CNC(=O)C2=CC(Cl)=CC=C12
1.7
ASAP-0016121
NCC1=CC=CC(NC(=O)[C@H](NC(=O)OCC2=CC=CC=C2)C2CCCCC2)=C1
2
ASAP-0016304
CC1=NOC(CCCOC2=C(C)C=C(C3=NOC(C(F)(F)F)=N3)C=C2C)=C1
4.2
ASAP-0015907
O=C(NCC1=CC=CC=N1)NC1=CNC(=O)C2=CC=CN=C12
0.9
ASAP-0015912
COC1=CC=CC=C1NC(=O)NC1=CNC(=O)C2=CC=CC=C12
2.2
ASAP-0015920
O=C(NCC1=CC=CC=N1)NC1=CNC(=O)C2=CC=C(F)C=C12
1
ASAP-0014722
C[C@H](C(=O)O)[C@@H](NC(=O)C1=NC=NC2=C1C=CN2)C1=CC=C(Br)C=C1
0.6
ASAP-0015682
O=C(O)C1=CC(Cl)=CC=C1NS(=O)(=O)C1=CC=C(OC2=CC=CC=C2Cl)C=C1
3
ASAP-0015381
COC1=CC=C([C@H](CC2=NN=NN2)NC(=O)C2=NC=NC3=C2C=CN3)C=C1
-0.5
ASAP-0015355
COC1=CC(CC2=C(C)ON=C2C2=CC=C(F)C=C2)=NC(N2CCNCC2)=N1
2.1
ASAP-0015367
NCC1=CC=CC(NC(=O)[C@@H](NC(=O)OCC2=CC=CC=C2)C2=CC=C(OCC3=CC=CC=C3)C=C2)=C1
3.2
ASAP-0015169
NC1=NN=C2C=CC(C3=CC=C4NC(=O)CNC4=C3)=CN12
0.8
ASAP-0014994
CNC(=O)C1=CC(Cl)=CC=C1NS(=O)(=O)C1=CC=C(OC2=CC=CC=C2Cl)C=C1
2.4
ASAP-0014913
CN1C=C(NC(=O)NCC2=CC=CC=N2)C2=CN=CC=C2C1=O
0.3
ASAP-0012944
O=C(/C=C/C1=CC=CC=C1)C(=O)N1CCN(CCC2=CC=CC=C2)CC1
3.3
ASAP-0014807
CC1=NC=CN1C[C@H](C)CNC(=O)C1=CC=C2COB(O)C2=C1
0.2
ASAP-0014822
C[C@H]1CN(C[C@H](O)CNC(=O)C2=CC=C3COB(O)C3=C2)CCO1
0
ASAP-0014818
CN1CCN(C)[C@H](CNC(=O)C2=CC=C3COB(O)C3=C2)C1
-0.5
ASAP-0014817
O=C(C1=CC=C2COB(O)C2=C1)N1CCN[C@H](C2=CC=CC=C2)C1
0.8
ASAP-0014813
O=C(C[C@H]1CCN2C=NC=C2C1)NC1=CC=CC(B(O)O)=C1
1.1
ASAP-0014761
CC1=CC(NC(=O)NC2=CNC(=O)C3=CC=CC=C23)=NO1
1.6
ASAP-0014724
CN1CC[C@H](NC(=O)C2=CC=CC(B(O)O)=C2)[C@H]1C1=CC=C(Cl)C=C1
2.8
ASAP-0014734
CN(C(=O)C1=CC=C2COB(O)C2=C1)[C@H]1CCN(C2CC2)C1
0.7
ASAP-0014739
O=C(NC1=CC=CC(B(O)O)=C1)[C@H]1CCN2CCC[C@H]2C1
0.3
ASAP-0014731
O=C(NC1=CC=CC(B(O)O)=C1)[C@H]1CCN(CC2=CC=CC=C2)C1
1.9
ASAP-0014613
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CC=NN=C1)C(=O)C1=CC=C(F)C=C12
1.2
ASAP-0014544
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CC=C(Cl)N=N2)C2=CC(Cl)=CC=C2C1=O
2.1
ASAP-0013892
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CN=CS2)C2=CC(Cl)=CC=C2C1=O
1.8
ASAP-0013898
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CCN1CCN(S(C)(=O)=O)CC1)C(=O)C1=CC=C(Cl)C=C12
1.8
ASAP-0013925
O=C1C2=CC=C(Cl)C=C2[C@@]2(CN1CCN1CCOCC1)C(=O)N(C1=CN=CC3=CC=CC=C13)C[C@@H]2CNC1=NC=CC=N1
1.9
ASAP-0013827
CCNC(=O)C1=CC2=C(N[C@H](C3=CC=C4OCCOC4=C3)C(C)C)N=CN=C2N1
3.6
ASAP-0013814
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=C(C)N=CS2)C2=CC(Cl)=CC=C2C1=O
2.1
ASAP-0013824
CCNC(=O)C1=CC2=C(N[C@H](C3=CC=C4OCCOC4=C3)C(C)C)N=CN=C2N1
3.6
ASAP-0013833
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(=O)N(C)C)N=C1)N2)C1=CC=C2OCCOC2=C1
2.9
ASAP-0013837
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(=O)N(C)C)N=C1)N2)C1=CC=C2OCCOC2=C1
3
ASAP-0013747
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(=O)N(C)C)N=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
2.2
ASAP-0013744
CC(C)[C@H](NC1=NC=NC2=C1C=C(C1=CN(CC(=O)N(C)C)N=C1)N2)C1=CC=C2CCCS(=O)(=O)C2=C1
2.2
ASAP-0013717
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CS(=O)(=O)NC)C2=CC(Cl)=CC=C2C1=O
1.3
ASAP-0013646
COC1=CC=C(C(=O)NC2=CC=CC(/C=C3/C(=O)NC(=O)C4=CC=CC=C34)=C2)C=C1
3.6
ASAP-0013722
CC1=NOC(CN2C[C@@]3(C(=O)N(C4=CN=CC5=CC=CC=C45)C[C@@H]3C)C3=CC(F)=CC=C3C2=O)=C1
2.1
ASAP-0013721
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=NN=NN1C)C(=O)C1=CC=C(F)C=C12
1.5
ASAP-0013720
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=NC=CN1C)C(=O)C1=CC=C(F)C=C12
2
ASAP-0013719
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC#N)C(=O)C1=CC=C(F)C=C12
1.7
ASAP-0013718
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CN2N=CN=N2)C2=CC(Cl)=CC=C2C1=O
1.1
ASAP-0013716
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CNC2=CN=C(C)S2)C2=CC(Cl)=CC=C2C1=O
1.9
ASAP-0013398
CCN1N=CC=C1CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(F)=CC=C2C1=O
2.3
ASAP-0013413
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CC=NN1C)C(=O)C1=CC=C(F)C=C12
2
ASAP-0013412
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=CNN=N1)C(=O)C1=CC=C(F)C=C12
1.7
ASAP-0013405
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CN2C=CC=N2)C2=CC(Cl)=CC=C2C1=O
1.9
ASAP-0013407
CNCCN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2C)C2=CC(F)=CC=C2C1=O
0
ASAP-0013414
C[C@H]1CN(C2=CN=CC3=CC=CC=C23)C(=O)[C@@]12CN(CC1=COC=N1)C(=O)C1=CC=C(F)C=C12
1.9
ASAP-0013423
CC1=CN=C(CN2C[C@@]3(C(=O)N(C4=CN=CC5=CC=CC=C45)C[C@@H]3C)C3=CC(F)=CC=C3C2=O)C=N1
2
ASAP-0013303
CNC(=O)CN1C[C@@]2(C(=O)N(C3=CN=CC4=CC=CC=C34)C[C@@H]2CS(=O)(=O)NC)C2=CC(F)=CC=C2C1=O
0.7