Datasets:
ranime
/
hetionet-instructions

Dataset card Data Studio Files
xet
 Community
1
messages
listlengths
2
2
[ { "role": "user", "content": "Does the compound Haloperidol associate with the gene DRD4?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Does Trazodone exhibit affinity toward the target gene DRD4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does the compound Stanozolol associate with the gene DRD4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could there be a biochemical interaction between Hydromorphone and DRD4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is it likely that Paroxetine binds to or modulates CHRM4?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Does current data suggest that Mazindol targets CHRM4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could Bosutinib interact directly or indirectly with CHRM4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can we infer a potential binding event between Glucosamine and CHRM4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Might Tiludronate bind functionally to the gene product of PTPN1?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Does current data suggest that Verteporfin targets PTPN1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there relationship between the drug L-Lysine and the gene PTPN1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there a link between Retapamulin and PTPN1 indicating a possible binding relationship?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is ATP1A4 a plausible target for the compound Digoxin?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Is there any known binding between Linaclotide and ATP1A4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can the compound Pipecuronium potentially interact with the gene ATP1A4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Would Roflumilast be able to bind ATP1A4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does current data suggest that Benzocaine targets SCN7A?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Can the compound Phenoxybenzamine potentially interact with the gene SCN7A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does current data suggest that Levobunolol targets SCN7A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does Ibutilide exhibit affinity toward the target gene SCN7A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is ADRA1B a plausible target for the compound Olanzapine?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Could there be a biochemical interaction between Maprotiline and ADRA1B?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there any known binding between Suprofen and ADRA1B?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does current data suggest that Leucovorin targets ADRA1B?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does current data suggest that Dipyridamole targets PDE6D?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Does the compound Nedocromil associate with the gene PDE6D?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Might Desonide bind functionally to the gene product of PDE6D?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Would Mesoridazine be able to bind PDE6D?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does Ceftizoxime exhibit affinity toward the target gene SLC15A1?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Would Ajmaline be able to bind SLC15A1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there relationship between the drug Halofantrine and the gene SLC15A1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can we infer a potential binding event between Trilostane and SLC15A1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does the compound Marimastat associate with the gene MMP7?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Could there be a biochemical interaction between Ketazolam and MMP7?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can the compound Cefditoren potentially interact with the gene MMP7?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there a link between Pamidronate and MMP7 indicating a possible binding relationship?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there any known binding between Amlodipine and CYP2C8?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Can the compound L-Aspartic Acid potentially interact with the gene CYP2C8?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could Zanamivir interact directly or indirectly with CYP2C8?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there any known binding between Ropivacaine and CYP2C8?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there relationship between the drug Guanidine and the gene KCNQ4?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Could there be a biochemical interaction between Tetrabenazine and KCNQ4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can the compound Phenazopyridine potentially interact with the gene KCNQ4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does the compound Prilocaine associate with the gene KCNQ4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there any known binding between Melatonin and CYP19A1?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Might Regadenoson bind functionally to the gene product of CYP19A1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could there be a biochemical interaction between Isopropamide and CYP19A1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Would Pargyline be able to bind CYP19A1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could Amiloride interact directly or indirectly with SCNN1D?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Does the compound Medrysone associate with the gene SCNN1D?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Would Carisoprodol be able to bind SCNN1D?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there a link between Pentostatin and SCNN1D indicating a possible binding relationship?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does the compound Vidarabine associate with the gene ADORA2A?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Can we infer a potential binding event between Marimastat and ADORA2A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Would Imipenem be able to bind ADORA2A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there any known binding between Tiludronate and ADORA2A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is it likely that Sevoflurane binds to or modulates GABRA6?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Is there a link between Ofloxacin and GABRA6 indicating a possible binding relationship?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can we infer a potential binding event between Morphine and GABRA6?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is GABRA6 a plausible target for the compound Pyridostigmine?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does the compound Cocaine associate with the gene SCN10A?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Could Moxifloxacin interact directly or indirectly with SCN10A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can we infer a potential binding event between Cytarabine and SCN10A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Might Vildagliptin bind functionally to the gene product of SCN10A?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there relationship between the drug Atomoxetine and the gene SLC6A4?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Can we infer a potential binding event between Moricizine and SLC6A4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is SLC6A4 a plausible target for the compound Aprepitant?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is it likely that Dasatinib binds to or modulates SLC6A4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can we infer a potential binding event between Imatinib and HIPK4?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Is HIPK4 a plausible target for the compound Ditazole?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could there be a biochemical interaction between Bicalutamide and HIPK4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could there be a biochemical interaction between Dihydroergotamine and HIPK4?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does Tolcapone exhibit affinity toward the target gene COMT?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Is there a link between Adefovir Dipivoxil and COMT indicating a possible binding relationship?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Can the compound Tipranavir potentially interact with the gene COMT?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does the compound Zuclopenthixol associate with the gene COMT?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does the compound Cinnarizine associate with the gene CACNA1G?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Is CACNA1G a plausible target for the compound Ketoprofen?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there any known binding between Fosfomycin and CACNA1G?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could Dexrazoxane interact directly or indirectly with CACNA1G?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Might Estrone bind functionally to the gene product of CYP2C9?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Would Fusafungine be able to bind CYP2C9?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does current data suggest that Thioridazine targets CYP2C9?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there any known binding between L-Carnitine and CYP2C9?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Might Proflavine bind functionally to the gene product of F2?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Could Isosorbide Mononitrate interact directly or indirectly with F2?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there a link between Clinofibrate and F2 indicating a possible binding relationship?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Would Zinc be able to bind F2?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there relationship between the drug Probenecid and the gene SLC2A9?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Does current data suggest that Famotidine targets SLC2A9?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Could there be a biochemical interaction between Tetrahydrobiopterin and SLC2A9?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is SLC2A9 a plausible target for the compound Dabigatran etexilate?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is it likely that Acetaminophen binds to or modulates CNR1?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Would Ethinamate be able to bind CNR1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Would Cinoxacin be able to bind CNR1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does current data suggest that Allopurinol targets CNR1?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Might Metoclopramide bind functionally to the gene product of CYP11B2?" }, { "role": "assistant", "content": "Yes" } ]
[ { "role": "user", "content": "Might Dimethyl sulfoxide bind functionally to the gene product of CYP11B2?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Does current data suggest that Clobazam targets CYP11B2?" }, { "role": "assistant", "content": "No" } ]
[ { "role": "user", "content": "Is there relationship between the drug Acetylcysteine and the gene CYP11B2?" }, { "role": "assistant", "content": "No" } ]