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67ceb846-ab6f-411b-8c28-d9e47f0fe14d | Most common cause of Papillary necrosis is | Diabetes Mellitus | Sickle cell anaemia | Analgesics | Pyelonephritis | 2c | single | Major causes of Papillary Necrosis1. Analgesic nephropathy2. Sickle cell nephropathy3. Diabetes with UTI4. Prolonged NSAID use Reference: Harrison&;s Principles of Internal Medicine; 19th edition; Chapter 340; Tubulointerstitial Diseases of the Kidney | Medicine | Kidney |
fd8ef88d-5c1d-408a-8821-22c2ad3a590f | Alzheimer's disease is associated with: September 2012 | Delerium | Delusion | Dementia | All of the above | 2c | multi | Ans. C i.e. Dementia Alzheimer's dementia Coical (NOT subcoical) dementia, Progressive, Associated with Apo E gene, Neurofibrillary tangles are seen and Donepezil is used in management | Psychiatry | null |
ebe354ca-9e17-4c7c-8d77-c2443abc2949 | Essential amino acids are all except: | Leucine | Lysine | Methionine | Proline | 3d | multi | 10 amino acid are essential - T - Threonine V -VALINE P- Phenylalanine A- Arginine T- Tryptophan M- Methionine I -Isoleucine L -Leucine L - Lysine 2 amino acid are semi essential -Arginine and histidine can be synthesized by adults and not by growing children | Biochemistry | DNB 2018 |
314a1cb9-da06-4362-a1fe-4b5a61a14392 | What is tuberculoma? | Granuloma present in the lungs | Tuberculous periapical granuloma | Tuberculous lesion of the lymph nodes | None of the above | 1b | multi | Tuberculosis may also involve the bone of the maxilla or mandible. One common mode of entry for the microorganisms is into an area of periapical inflammation by way of the blood stream; an anachoretic effect.
It is conceivable also that these microorganisms may enter the periapical tissues by direct immigration through... | Pathology | null |
8bcfe52e-721e-419b-b49e-3dc053045196 | Clinical features of rheumatic fever are all except- | Cardiomegaly | Joint pains | ST segment elevation | Increased PR interval | 0a | multi | Ref: R Alagappan - Manual of Practical Medicine 4th Edition.pg no:146-147 Rheumatic Fever Acute, recurrent, inflammatory disease, mainly of children (aged 5-15 years), typically occurring 1-5 weeks after group A streptococcal infection. Pathophysiology 1. Cross reactivity of host antistreptococcal antibodies to cardiac... | Medicine | C.V.S |
95443365-5133-4755-885b-b06fbe019af5 | A dense persistent nephrogram may be seen in all of the following except: | Acute ureteral obstruction | Systemic hypeension | Severe hydronephrosis | Dehydration | 1b | multi | B i.e. Systemic hypeension | Radiology | null |
dd2a0d9a-28f5-4679-9d0b-9d9c8f4d0e29 | Most common type of mesentric cyst is | Entergenous cyst | Chelolymphalic cyst | O mental cyst | Urogenital cyst | 1b | single | Chelolymphalic cyst :
It is commonest type of mesentric cyst.
It has congenital misplaced lymphatic tissue. | Surgery | null |
33adc3f0-e555-474f-841d-c61beb8963ed | According to WHO, membranous glomerulonephritis seen in SLE, is - | Class II | Class III | Class IV | Class V | 3d | single | Ans. is 'd' i.e., Class V | Pathology | null |
b6154c1e-79ee-461a-8c9e-1f7063c25db5 | All the following can be used to grow human viruses except? | Continuous cell lines | Suckling mice | Embryonated egg | Enriched media | 3d | multi | The virus needs cellular components for there growth | Microbiology | Virology |
3211af99-26bf-4fa3-a702-924410320c6c | When a child is not able to perform the following motor functions such as skipping, walking on heels, hopping in place or going forwards in tandem gati, his motor development is considered to be below ? | 3 years | 4 years | 6 years | 8 years | 1b | single | Ans. is 'b' i.e., 4 years o A child hops on one foot by 4 years and skips by 5 years. o As this child can not hop, the age of this child is less than 4 years. | Pediatrics | null |
8cb58471-ef9b-485d-89cb-89b15929bab3 | The alveoli are filled with exudate. The air is displaced, converting the lung into a solid organ. This description suggests- | Chronic bronchitis | Bronchial asthma | Bronchiectasis | Lobar pneumonia | 3d | single | • ‘Bacterial invasion of the lung parenchyma causes the alveoli to be filled with an inflammatory exudate, thus causing consolidation (“solidification”) of the pulmonary tissue’…..Robbins definition of pneumonia | Pathology | null |
8898babd-1c9e-4fbf-8cc6-2ac2d9364eeb | Antoni A & Antoni B Pattern's are seen in | Schwannoma | Neurofibroma | Meningioma | Teratoma | 0a | single | Schwannoma *Distinctive histologic patterns seen within the peripheral nerve sheath tumor Schwan noma include the Antoni A and Antoni B regions oThese are the classic microscopic appearances of a schwannoma, which is benign. oNote the more cellular "Antoni A" pattern on the left with palisading nuclei surrounding pink ... | Surgery | null |
73a922a7-4e62-497c-8246-1fdb550e29c2 | Incised wound which is not a feature ? | Length is the greatest dimention | Width is more than the thickness of the blade | Margins are inveed | Hesitation cuts are seen in suicidal attempt | 2c | single | Ans. is 'c' i.e., Margins are inveed Margins are eveed, clear, and clean cut. | Forensic Medicine | null |
ede0c847-d6e8-47f4-9442-6912bb0e2124 | Which among the following NOT a pharmacological action of opioids | Cough suppression | Anti-emesis | Miosis | Truncal rigidity | 1b | single | null | Pharmacology | null |
466854b8-df37-4c54-b353-c104058b0846 | Which one of the following is a malignant bone tumour? | Osteoid osteoma | Chondroma | Chondrosarcoma | Osteochondroma | 2c | single | (C) Chondrosarcoma # MALIGNANT PRIMARY BONE TUMORS include osteosarcoma, chondrosarcoma, Ewing's sarcoma, malignant fibrous histiocytoma, fibrosarcoma, and other sarcoma types. Multiple myeloma is a hematologic cancer which also frequently presents as one or more bone tumors.# CLASSIFICATION of BONE TUMOURS:> Cartilage... | Orthopaedics | Miscellaneous |
2a8fd512-a3c3-495d-abb9-414f08273de8 | New born term baby born by vaginal delivers' had respiratory' distress, grunt, with scaphoid abdomen -Most probable diagnosis is - | HMD | Diphragmatic hernia | Pneumothorax | Meconium aspiration syndrome | 1b | single | Ans. is 'b' i.e., Diaphragmatic hernia o Diaphragmatic Hernia is defined as a communication between abdominal & thoracic cavities with or without abdominalContents in thorax.MC Bochdalek type.More common on left (85%)30% of CDH have associated anomalesCardiac anomalis is MC anomalis.In cardiac (Hypoplastic left heart s... | Pediatrics | Disorders of the Respiratory Tract |
06c22c8b-b4d1-47e5-941a-807cdb23bd24 | Confirmatory test for syphilis is-rpt qun | FTA-ABS | VDRL | PCR | Culture and sensitivity | 0a | single | rpt qun | Microbiology | Bacteriology |
4b5598b2-e166-4a6b-bd05-9debb46d2d87 | The placenta secretes a hormone that is utilized in the early detection of pregnancy. This hormone is: | Endothelial growth factor (EGF) | Human chorionic gonadotropin (hCG) | Human chorionic somatotropin (HCS) | Relaxin | 1b | single | The synthesis and secretion of hCG begins about day 6 of pregnancy, presumably from the trophoblast cells. Pregnancy tests utilize the measurement of hCG for detection of the embryo. Endothelial growth factor (EGF) is synthesized by the cytotrophoblast cells in the early placenta, then is synthesized by the syncytiotro... | Physiology | null |
2e50b900-3b19-43e9-bfb9-351ce8907426 | Ulceration of the vulva is commonly seen in all except | Bacterial vaginosis | Syphilis | Chancroid | Behcet's disease | 0a | multi | Ans. is a, i.e. Bacterial vaginosisRef: Dutta Gynae 6th/ed, p262Vulval ulcersVulval ulcers are predominantly due to sexually transmitted diseases. Rarely, it may be due to non-specific causes.Malignant ulcer is also rare. The various etiological factors related to vulval ulcers are given in the below Table.Ulcers of th... | Gynaecology & Obstetrics | Sexually Transmitted Disease in the Female |
7d3a48c9-9cfe-4a48-b402-cb45913c8a2d | Thalidomide can be used in all of the followingconditions except? | Behcet syndrome | HIV associated peripheral neuropathy | HIV associated mouth ulcers | Erythema nodosum leprosum | 1b | multi | HIV associated peripheral neuropathy | Pharmacology | null |
63f37b72-1533-4ca9-985c-1fc78ad9caaa | In children with classical galactosemia all are true except: | E. coli neonatal sepsis is common | Elimination of galactose in diet will not reverse cataract | Galactose conves to galactitol which is toxic to brain | Children with Duae variant of galactosemia are asymptomatic | 1b | multi | E. coli sepsis is common and the onset often precedes the diagnosis of galactosemia Elimination of galactose reverse growth failure, cataract, renal and hepatic dysfunction Galactokinase deficiency -> accumulation of galactose and galactitol Duae variant- a single amino acid substitution, has 50% of normal enzyme activ... | Pediatrics | Disorders of Carbohydrate Metabolism |
1871cc41-1e63-4584-a2fe-8b62b4e136b3 | When a person changes position from standing to lying down, following change is seen: | Hea rate increases | Venous return to hea increases immediately | Cerebral blood flow increases | Blood flow at apices of lung decreases | 1b | single | B i.e. Venous return to hea increases immediately In standing posture, 300- 500m1 of blood pools in venous capacitance vessels of lower extremities, which is immediately returned towards heaQ on assuming lying down posture. Cardiovascular system Onlying On standing - Stroke volume - Cardiac output - Venous return - Cen... | Physiology | null |
58cb2f04-f0c1-4ff8-b693-ad8734746d6b | Metrorrhagia is | Heavy menstrual bleeding | Intermenstrual bleeding | Break through bleeding | Post coital bleeding | 1b | single | The term intermenstrual bleeding is updated nomenclature for metrorrhagia. | Gynaecology & Obstetrics | null |
4600d02f-5965-4b62-8549-0626a3952919 | Effective red cell diameter | Different in males and females | Diameter of 500 microns | Thalassemia minor anemia may present with normal RBC diameter | Mixed iron and folic deficiency anemia produce microcytic | 2c | single | Answer: (C) Thalassemia minor anemia may present with normal RBC diameter (265-68-Hrshmohon 7th) (630= Rabbins- basis disease)Red blood cell distribution width (RDW or RCDW) is a measure of the variation of red blood cell (RBC) volume that is reported as part of a standard complete blood count. Usually red blood cells ... | Pathology | Blood |
0373c995-1375-4b64-b4fc-757f2ee9055c | The most impoant indication for surgical repair of a Bicornuate Uterus is - | Infeility | Dysmenorrhoea | Menorrhagia | Recurrent aboions | 3d | single | The most impoant indication for surgical repair of a Bicornuate Uterus is Recurrent aboions Recurrent aboions occur due to - Decreased space for embryo to grow and Relatively less blood supply | Gynaecology & Obstetrics | Aboions, Spontaneous & Induced Emergency Contraception (Hey,whats the hurry !) |
e8a22fc1-13a5-4097-a643-4c67ec2b090b | Uses of α2 agonists are all EXCEPT: | To produce sedation | Glaucoma | Benign hyperplasia of prostate | Hypertension | 2c | multi | null | Pharmacology | null |
f52691c3-72ef-4683-808b-fb8ce8418f83 | Treatment of solitary rectal ulcer are A/E:a) Laxativesb) Rectopexyc) Bandingd) Sclerosant injectione) Enema | cd | bc | bd | ac | 0a | single | null | Surgery | null |
4a2d3570-642b-4afb-812a-761a67380ef9 | Craniotabes is seen in following except – | Rickets | Syphilis | Osteogenesis imperfecta | Thalassemia | 3d | multi | null | Pediatrics | null |
686cd2ab-481a-4ae2-9939-5de79056ae75 | Maternal moality rate is - | Maternal deaths / 100000 live bihs | Maternal death /100 live bihs | Maternal death /1000 bihs | Maternal death /1000 live bihs | 0a | single | Park&;s textbook of preventive and social medicine 23rd edition. * Maternal moality rate is the no of maternal deaths in a given period per 100,000 women of reproductive age during the same time period. | Social & Preventive Medicine | obstetrics,pediatrics and geriatrics |
7010f58c-0284-4199-bf04-72b8821ca5a2 | Colour of crystals in positive Florence test is - | Yellow | White | Purple | Dark Brown | 3d | single | Ref:The essential of forensic medicine and toxicology Dr.K.S NARAYAN REDDY 32nd edition pg no 415 the stain is estracted by 10% HCL and a drop is placed on a glass slide and allow to dry a cover slip is place dover this , and a drop of florence solution(KI,iodide and water) this allowed to run under the cover slip .if ... | Forensic Medicine | Special topics |
039f5c62-0aad-41af-af51-6f98b51cd97e | Factor Xa is necessary for conversion of prothrombin to thrombin | Only in the extrinsic pathway | Only in the intrinsic pathway | As part of both extrinsic and intrinsic pathways | Only if the normal blood clotting cascade is inhibited | 2c | multi | Ans. (c) As part of both extrinsic and intrinsic pathways(Ref: Robbins 9th/pg 118-119; 8th/pg 119)Activated factor IX along with factor VIIIa (Intrinsic pathway) & factor VIIa (extrinsic pathway), converge to activate Factor X to Xa is necessary for conversion of prothrombin to thrombin (common pathway) | Pathology | Bleeding Disorders |
abec181b-7779-41cf-87de-124ae93f5e69 | True about Rotameter – | Rotameter reading may not get affected by dirt inside the tube | Rotameter reading may not get affected by static electricity | The height to which bobbin rises indicates the flow rate | A rotameter is a variable pressure flowmeter | 2c | multi | As the gas flows through the rotameter, bobbin rises and the upper end of bobbin determines the flow rate.
Rotameter works on variable area (variable orifice) and constant pressure principle (not variable pressure).
Causes of inaccurate reading in rotameter are :- Static electricity, Dirt inside the tube, Non-vertical ... | Anaesthesia | null |
7c5f7238-1b8d-4c64-a1cc-1ed6965d42f0 | Neurocysticercosis is treated by all the following drugs, EXCEPT - | Albendazole | Niclosamide | Flubendazole | Praziquantel | 1b | multi | null | Medicine | null |
78647e01-58cb-4288-98b9-1044314042fb | What is an ideal method to prevent aspiration pneumonia? | Cuffed endotracheal tube | Inhalational anaesthesia | Increased intra abdominal pressure | Full stomach | 0a | single | Ans: A (Cuffed endotracheal tube) Ref: Bailey, 24th ed, p. 46; Ajay Yadav, p. 101A cuffed endotracheal tube is used to:1. Facilitate artificial airway ventilation or surgery around face or airway.2. Protection of lung if there is a risk of pulmonary aspiration.Predisposing factors for aspiration:1. Full stomach-- singl... | Unknown | null |
9d401433-8335-487e-8723-fcfc3b43c520 | A mutation that results in a value replacement for glutamic acid at position 6 of the B chain of hemoglobin 5 hinders normal hemoglobin function and results in sickle-cell anemia when the patient is homozygous for this mutation. This is an example of which of the following types of mutation? | Deletion | Frameshift | Inseion | Missense | 3d | single | Missense mutations are those in which a single base change (point mutation) results in a codon that encodes for a different amino acid residue. The effects of these types of mutations can range from very minor or even undetectable to major, depending on the impoance of the altered residue to protein folding and functio... | Biochemistry | null |
1c6b51f6-061b-4337-be54-7a3afdb0121a | Which of the following vessel does not cross the midline of the body: | Left gonadal vein | Left renal vein | Left brachiocephalic vein | Hemiazygous vein | 0a | single | The left gonadal vein drains into the left renal vein which crosses the midline to join inferior vena cava. All the other options (Left renal vein, left brachiocephalic vein and hemiazygous vein) cross the midline.Ref: Human Anatomy, B D Chaurasia, 4th Edition, Volume 2, Chapter 24, Page 297, 307, 316; Clinical Anatomy... | Anatomy | null |
88f65fcf-7f12-4cd9-a59d-7e1933832055 | Daily maintenance fluid for a child weighing 24 kg is: | 1000 mL/day | 800 mL/day | 1540 mL/day | 1580 mL/day | 3d | single | Fluid requirement in a child in this child weighing 24 kg is:1540 mL. For first 10 kg: 100ml/kg For next 10 kg : 50ml/kg For each kg. above 20 : 20 ml/kg (1-10 kg) 100 x 10 = 1000 mL (11-20 kg) 50 x 10 = 500 mL; For next 4 kg (21-24 kg) 20 x 4= 80 mL | Pediatrics | Fluid, Electrolyte |
21ccfd25-2de4-4c76-a545-4e8e20990135 | OCP protects against all EXCEPT: September2012 | Hepatic adenoma | Fibroadenoma breast | Carcinoma ovary | Uterine malignancy | 0a | multi | Ans. A i.e. Hepatic adenoma OCP's administration may result in hepatic adenoma. Oral contraceptive pills Protects against: - Uterine Ca, - Ovarian Ca, - RA, - Endometriosis etc. | Gynaecology & Obstetrics | null |
9d9ab080-4904-4d16-8c55-91d9f246d59e | In a chronic alcoholic, all the following may be seen in the liver except - | Fatty degeneration | Chronic hepatitis | Granuloma formation | Cholestatic hepatitis | 2c | multi | Alcoholic liver disease
There are three distinct forms of liver disease -
1. Hepatic steatosis (fatty liver)
2. Alcoholic hepatitis
(a) Acute alcoholic hepatitis
Focal necrosis
Cholestasis
Mallory hyaline bodies
(b) Chronic hepatitis
3. Alcoholic cirrhosis | Pathology | null |
d72f1d0f-b091-48f0-8986-c1920d587db4 | Ring sideroblasts, with iron laden occurs in | Endoplasmic reticulum | Nucleus | Mitochondria | Nuclear membrane | 2c | single | i.e. (Mitochondria) : (301-Harsh Mohan 6th ) (625-Robbins & Cotran-Pathologic basis of disease 8th)Ringed sideroblasts is characteristic of sideroblastic anemia /Myelodysplastic SyndromeRinged sideroblast in which haem synthesis is disturbed as occurs in sideroblastic anaemiasRinged sideroblasts containing numerous lar... | Pathology | Blood |
20bea810-4e48-472f-9763-77c1bc4abfc6 | Signal from Baroreceptors goes to - | Caudal ventrolateral medulla | Rostral dorsolateral medulla | Nucleus of tractus solitarius | None of the above | 2c | multi | Ans. is C Nucleus of tractus solitarius o Baroreceptors are mechanoreceptors that are located in the adventia of carotid artery and aorta, at specialized locations called sinuses. Carotid sinus is a little bulge at the root of internal carotid artery, located just above the bifurcation of the common carotid artery. It ... | Unknown | null |
6a25c0d5-4d53-429a-ac5c-0bf0145cba6d | Intrinsic factor of castle is secreted by which of the following cells in gastric glands | Chief cells | Parietal cells | Enterochromaffin cells | B cells | 1b | single | The stomach also adds a significant volume of digestive juices to the meal. Like salivary secretion, the stomach actually readies itself to receive the meal before it is actually taken in, during the so-called cephalic phase that can be influenced by food preferences. The gastric secretions arise from glands in the wal... | Physiology | G.I.T |
424f3042-0451-4000-b7b0-98263483b83b | Which is not echogenic while doing ultrasonography- | Bile | Gas | Bone | Gall stones | 0a | multi | Bile and urine are least echogenic.
Bone, gas, and organ boundaries are most echogenic. | Radiology | null |
90c70586-ea3f-41f4-8ac1-708dc4adf6a8 | Features of mycotic aneurysm are all except | Bacterial endocarditis is common etiology | Commonly it is fusiform aneurysm | Aorta and visceral vessels affected commonly | Multilobed aneurysm with narrow neck | 1b | multi | Mycotic aneursm is commonly saccular. | Surgery | null |
69eaa494-e859-4153-8835-b552dddc2d21 | Microvesicular fatty liver is caused by - | DM | Valproate | Starvation | IBD | 1b | single | Ans. is 'b' i.e., Valproate Steatosiso Accumulation of triglyceride fat droplets within the heaptocytes is known as steatosis or fatty liver. It may be of two types -1. Microvesicular steatosis - Multiple tiny droplets accumulate that do not displace the nucleus.2. Macrovasicular steatosis - A single large droplet accu... | Pathology | Liver |
4319f41c-953a-4903-82a9-96c4b32c6849 | Child protection scheme is under which ministry - | Ministry of health and family welfare | Ministry' of Social welfare | Ministry' of women and child development | Ministry of education | 2c | single | Ans. is 'c' i.e., Ministry of women and child developmento In 2006 the Ministry' of Women and Child Development (MWCD) proposed adoption of Integrated Child Protection Scheme (ICPS).o In 2009 the central government take the scheme its approval and has begun the extensive task of providing children with a protective and... | Social & Preventive Medicine | Health Programmes in India |
7084cbc3-05da-4499-bfb4-df024e39ebe5 | Indication for surgery in a case of adrenal incidentaloma | Size>5 cm | Bilateral adrenal metastasis | Functional tumor | All of the above | 3d | multi | Ref: Bailey&;s 26thE pg: 780. Treatment of Incidentaloma: Any non-functioning adrenal tumour greater than 4 cm in diameter and smaller tumours that increase in size over time should undergo surgical resection. Non-functioning tumours smaller than 4 cm should be followed-up after 6, 12 and 24 months by MRI and hormonal ... | Surgery | Endocrinology and breast |
06d06437-d265-4554-ab42-19b43d7aa768 | In case control study of buccal carcinoma- | CA is commoner in zarda pan users than non users | Zarda pan is a cause of buccal CA | Zarda pan is associated with buccal CA | If use of zarda pan is stopped, number of cases will reduce | 2c | single | Case control studies often retrospective studies are a common first approach to test causal hypothesis. In recent years case control study has emerged as a permanent method of epidemiological investigation. Both exposure and outcome has occurred before the study. Study proceeds backwards from effect to cause. It uses a... | Social & Preventive Medicine | Epidemiology |
55ba5eb4-7157-40c5-988f-26f06ff082f9 | Nephrotic syndrome is characterised by | Proteinuria | Hyperlipidemia | Oedema | All | 3d | multi | Ans. is 'a' i.e., Proteinuria; 'b' i.e., Hyperlpidemia; 'c' i.e., Oedema Pathophvsiologv of nephrotic syndrome Proteinuria o The most impoant feature of nephrotic syndrome is massive proteinuria (>3.5 gm/day) o Proteinuria results from altered permeability of glomerular filtration barrier for protein. o The largest pro... | Pathology | null |
821f6586-f2f3-4fee-9c2f-eb7e53aa5a03 | All the following are the risk factors for cervical cancer except | Young age at first intercourse | Multiple sexual paners | Low parity | Low socioeconomic status | 2c | multi | There are numerous risk factors for cervical cancer: Young age at first intercourse (younger than 16 years), Multiple sexual paners, Cigarette smoking, race, High parity, Low socioeconomic status, and Chronic immune suppression. Reference: Novak's gynaecology; 14th edition; Chapter 35; Uterine cancer | Gynaecology & Obstetrics | Gynaecological oncology |
addd9f5a-ff2d-4161-a9f7-8409749ff195 | Characteristic feature of korsakoff psychosis is | Disorientation | Delirium | Coarse tremor | Amnesia | 3d | single | null | Medicine | null |
e64863b6-ded9-4aa5-b987-b06de7b394d3 | Person preoccupied by worries about ill health is : | Hypochondriac | Maniac | Depressed | Delirium | 0a | single | A i.e. Hypochondriasis | Psychiatry | null |
07e8f3a1-63b5-4eae-a132-0286b9ef48d3 | Terminal branches of facial nerve are all, EXCEPT: | Mandibular nerve | Marginal branch | Temporal | Cervical | 0a | multi | The facial nerve crosses lateral to the styloid process and penetrates the parotid gland. In the parotid gland, the nerve divides at the pes anserinus into 2 major divisions; ie, the superiorly directed temporal-facial and the inferiorly directed cervicofacial branches. After the main point of division, 5 major branche... | Anatomy | null |
d53153f0-8be3-4794-9307-aafc24da8c85 | Which of the following is orexigenic? | Serotonin | Ghrelin | OCX | GA | 1b | single | Ghrelin: Anorexigenic and somatotrophic signal from the stomach Akio Inui1 About the author top of page Abstract Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is synthesized principally in the stomach and is released in response to fasting. Ghrelin is structurally related to motilin and, t... | Physiology | General physiology |
455bf6be-62c3-4ec0-ba1e-eafa0b49459b | Metformin is NOT effective in lowering of blood sugar level in which of the following patients? | Non diabetics | Obese diabetics | Type 2 diabetics | Diabetics not responding to sulfonylureas | 0a | single | (Ref:KDT 6/e p269) Metformin is the drug of choice for the treatment of obese diabetic patients, as it causes weight loss. It does not cause release of insulin, therefore less chances of hypoglycemia. | Anatomy | Other topics and Adverse effects |
9f553c15-928f-41f8-8e94-021521702b9b | You are conducting a survey in your village and the person you are interviewing is a 32 year old post graduate working as a clerk. His total family income is 20,000 Rs per month. According to Kuppuswamy's socio economic status scale, he belongs to: | Upper socioeconomic class | Upper socioeconomic class | Lower middle socioeconomic class | Upper lower socioeconomic class | 1b | single | Kuppuswamy's socio economic status scale takes into account education, occupation and monthly family income. Since he is a post graduate he gets 6 points for education. His job as a clerk gives him 5 points and a monthly family income of 20000 Rs gives him 12 points which gives him a total of 23 points and so he belong... | Social & Preventive Medicine | null |
3bad04f5-219b-4bb5-ae68-388ffbc6415f | True regarding the development of ear: | Eustachian tube opens at the level of interior turbinate | Pinna develops from the cleft of Ist arch | Growth of the inner- ear completed by 4th month | All | 3d | multi | A i.e. Eustachian tube opens at the level of inferior turbinate; B i.e. Pinna develops from the cleft of arch; C i.e. Growth of inner ear completed by 4th monthEustachian tube connects tympanic cavity with nasopharynx. It is about 36cm long in adults and runs downwards, forwards & medially at an angle of 45deg with hor... | Anatomy | null |
6c222a4a-e7b4-49f9-a9ee-e09f8545f7df | Gastric irritation is least with following NSA1D: (PGI June 2008) | Diclofenac | Acetaminophen | Ibuprofen | Naproxen | 1b | single | Ans. B (Acetaminophen) "Gastric mucosal damageQ: Gastric pain, mucosal erosion/ ulceration and blood loss are produced by all MSAIDs to varying extents: relative gastric toxicity is a major consideration in the choice of MSAIDs. Paracetamol", a very weak inhibitor of COX is practically free of gastric toxicity and sele... | Pharmacology | Prostaglandins |
bbfbb8af-7798-4233-8908-54a4b8611430 | The concetration of potassium in microgram in ORS is- | 30 meq | 20 meq | 90 meq | 60 meq | 1b | single | Ans. is 'b' i.e., 20 meq | Pediatrics | null |
64f80edc-9494-4b09-b361-0d50d21ff9cb | Abnormal mousy/mushy odour of urine is associated with | Phenylketonuria | Tyrosinemia | Maple syrup urine disease | Hawkinsuria | 0a | single | Ans. a (Phenylketonuria) (Ref. Harrison's Internal Medicine 17th/Ch. 358)Inborn errors of amino acid metabolism associated with abnormal odourInborn error of metabolismUrine odorGlutaric acidemia (type II)Sweaty feet, acridHawkinsinuriaSwimming poolIsovaleric acidemiaSweaty feet, acridMaple syrup urine diseaseMaple syr... | Pediatrics | Inborn Errors of Metabolism |
38ccb378-9091-4565-a595-bfd77b13ea9a | Clinical features of infectious mononucleosis | Glandular involvement | Febrile | Palatine petechiae | All of the above | 3d | multi | null | Pathology | null |
cae8e457-d314-4013-b5a3-15fc16015f33 | Small cuff size will lead to? | Falsely increased BP | Falsely low BP | No effect on BP | Fluctuating BP | 0a | multi | a. Falsely increased BP(Ref: Nelson's 20/e p 2164)In older children, a mercury sphygmomanometer with a cuff that covers approximately two-thirds of the upper part of the arm or leg may be used for blood pressure measurement. A cuff that is too small results in falsely high readings, whereas a cuff that is too large rec... | Pediatrics | Miscellaneous |
8ea4240e-bfb6-448a-9a91-288b8198fd93 | Ulcer with undermined edges is seen in | Malignant ulcer | Tubercular ulcer | Venous ulcer | Diabetic ulcer | 1b | single | Tubercular ulcers typically have undermined edges. Reference: Bailey & Love&;s Sho Practices of Surgery 27th Edition, Page no. 78 | Surgery | General surgery |
f52cfc68-7b88-4f84-9a79-117dbce9da60 | Which of the following is NOT associated with elevation of prostatic specific antigen? | Acute prostatitis | BPH | Prostatic intraepithelial neoplasm | Prostatic needle biopsy | 2c | single | Prostatic Intraepithelial Neoplasia ( PIN) is a precancerous condition; not detected by rectal examination, TRUS , or MRI; does not cause rise in PSA level . It is usually identified after TURP for BPH with final histology or by prostatic biopsy.Reference: page1048 SRB&;s manual of surgery 5th edition | Surgery | Urology |
fa1276ec-3538-4c56-a23c-85732a5eb5b1 | Muscle relaxant used in renal failure : | Ketamine | Atracurium | Pancuronium | Fentanyl | 1b | single | B i.e. Atracurium | Anaesthesia | null |
17073b03-4f15-462e-86f2-79428819b591 | Redistribution phenomenon is seen in: | Halothane | Ether | Thiopentone | All | 2c | multi | null | Pharmacology | null |
b634a7e2-4f0b-4d25-ba86-3da9ccf4726a | A 20 years female has hepatosplenomegaly, fever, pallor and generalized lymphadenopathy. Lab test useful for diagnosis is/are -a) ESRb) Electrophoresisc) Parasite detection in aspirated) ELISAe) Routine haemogram | acd | ace | cde | ade | 1b | multi | null | Microbiology | null |
3a963c53-2aa9-4e2c-96e4-4570516f18fb | Gastrinoma a/w | Diarrhoea | Constipation | Achlorhydria | Multiple superficial gastric ulcers | 0a | single | Diarrhoea is due to hypergastrinaemia.It is associated with severe ulcers,not superficial SRB's manual of surgery,5th edition,710. | Surgery | G.I.T |
d9fd0e3c-af5e-4108-abd5-6e5c40f71bab | CAGE questionnaire is used in:AP 07; MP 09; NEET 13 | Alcohol dependence | Opiate poisoning | Dhatura poisoning | Barbiturate poisoning | 0a | single | Ans. Alcohol dependence | Forensic Medicine | null |
966accb6-3050-4ff9-9e8f-9b9d46f44bea | Which of the following is used in exocytosis? | Ca | Mg | Na | K | 0a | single | Ans. (a) CaExocytosis is a calcium dependent process where in the cellular contents are moved out of the cell in the form of vesicles (Cell Vomiting) | Physiology | General |
4d208459-fcab-41dc-a5b7-d984359ac2b9 | Therapeutic blood range of theophylline in microgram per L is: | 0-5 | 10-May | 15-May | 20-May | 3d | single | Theophylline is having a narrow margin of safety so therapeutic drug monitoring is essential If levels increase more than 20mg/L- side effects occurs ESSENTIAL OF MEDICAL PHARMACOLOGY SEVENTH EDITION KD TRIPATHI PGNO.226 | Pharmacology | Respiratory system |
00f2c259-7b5b-407e-81f1-172da8846455 | Lift off test is used for which of the following muscles? | Supraspinatus | Subscapularis | Infraspinatus | Biceps Breachii | 1b | single | Ans. is 'b' i.e., Subscapularis TestMuscle TestedLift off testSubscapularisJobe testSupraspinatusSpeed testBicepsYergason testBicepsBelly press testSubscapularis | Orthopaedics | Injuries Around Shoulder |
26b146ff-0f13-4e9d-b4fe-d3aac7fd1f7d | Which of the following is not a structural element of TMJ? | Sigmoid notch | Articular disc | Capsular ligament | Joint cavities | 0a | single | Sigmoid notch (or) mandibular notch forms the sharp upper border of the ramus the condyle and coronoid process. | Dental | null |
10ff3d1e-3020-4a37-956e-a1bc43b06fc8 | Prognostic stage groups in carcinoma breast include all except | Tumour size | Grade | HER-2 status | Age | 3d | multi | Prognostic stage groups include TNM plus grading, and status of biomarkers HER-2, ER, and PR Ref: AJCC 8th edition | Surgery | Endocrinology and breast |
e11268cf-9f08-491b-8937-3875cbd26f46 | Arrange the following subtypes of schizophrenia, in order of prognosis, with the best prognosis first and the worst prognosis last, 1. Paranoid schizophrenia2. Catatonic schizophrenia3. Simple schizophrenia4. Disorganised schizophrenia | 4-2-1-3 | 2-1-3-4 | 2-1-4-3 | 1-2-4-3 | 2c | single | The correct sequence is Catatonic schizophrenia followed by Paranoid schizophrenia followed by Disorganised schizophrenia followed by Simple Schizophrenia Please remember in both DSM-5 and ICD-11, these subtypes have been removed | Psychiatry | Schizophrenia Spectrum and Other Psychotic Disorders |
92659a1c-5537-4957-ba76-a9c6551a8730 | Mammalian Mitochondria are involved in all of the following Except | Fatty acid synthesis | DNA synthesis | Fatty acid oxidation (b-oxidation) | Protein synthesis | 3d | multi | Protein synthesis is a cytoplasmic process.Fatty acid synthesis stas with the production of Acetyl Co-A within the mitochondria. b-oxidation of fatty acid oxidation also occurs in mitochondria. Mitochondrial DNA synthesis occurs within the mitochondria. | Microbiology | All India exam |
46385fe7-8048-4d88-86e2-fea7ab1cef01 | Cross examination of the prosecution witness is done by- | Public prosecutor | Defence counsel | Judge | None | 1b | multi | In government prosecutions, cross examination is done by defense lawyer. | Forensic Medicine | null |
802fc468-07e6-4fe2-af8b-5843c890a6b2 | Pseudo pocket is seen in the | Base of the pocket lies on cementum | Gingivitis | Periodontitis | Base of the pocket and lies on alveolar bone | 1b | single | null | Dental | null |
da060f81-4590-4c94-a8e7-76d29351bb61 | Thickness of oxygen inhibition layer in composite curing is: | 1-50 micrometer | 15-150 micrometer | 50-500 micrometer | 1000-2000 micrometer | 2c | single | When composite is light cured, oxygen in the air causes an interference in the polymerization resulting in the formation of an oxygen inhibition layer on the surface of the composite.The oxygen-inhibited layer is the sticky, resin-rich uncured layer that is left on the surface.Thickness is about 50-500 micrometer.
Refe... | Dental | null |
61b825a9-0c74-4550-925c-ccd161969c2a | Hassall&;s corpuscles are present in | Thymus | Lymphnode | Spleen | Liver | 0a | multi | Inderbir Singh's Human Histology Sixth edition Pg 140 The medulla of thymus contains pink staining rounded masses called the corpuscles of Hassal | Anatomy | General anatomy |
84911b71-e906-4984-8346-6418c0aed663 | Triamterene causes | Better glucose tolerance | Muscle cramps | Decrease in urea level | Hypokalemia | 1b | single | Inhibitors of renal epithelial Na+ channel Include Triamterene and amiloride. Triamterene:- It is incompletely absorbed orally, paly bound to plasma proteins, largely metabolized in liver to an active metabolite and excreted in urine. Plasma t 1/2 is 4 hours, effect of a single dose lasts 6-8 hours. Side effects:- cons... | Pharmacology | Kidney |
f885e11a-4a80-464f-aa2a-9bdaa6baff55 | Persistent vomiting in G.O.O. causes -a) Hyponatremic hyperchloremia occurb) Hypernatremia without ↓ed Cl- alkalosisc) Hypokalemic metabolic alkalosisd) Paradoxical aciduria | cd | bc | bd | ac | 0a | single | Repetitive vomiting leads to hypochloremic, hypokalemic metabolic alkalosis. The urine is alkaline initially but eventually it becomes acidic (paradoxical aciduria)
Cause of paradoxical aciduria
Initially the kidney compensate for metabolic alkalosis by reabsorbing hydrogen and chloride ions in exchange for sodium... | Surgery | null |
cdf04af4-0d45-4d27-8595-36b6c320df52 | All are immediate causes of death in burns except | Injury | Suffocation | Toxemia | Shock | 2c | multi | Immediate causes of death in burns Shock Suffocation Injury Delayed causes of death Toxemia Inflammatory complications Ref: TEXTBOOK OF FORENSIC MEDICINE AND TOXICOLOGY KRISHNAN VIJ FIFTH EDITION PAGE 163 | Forensic Medicine | Thermal injury |
b2f91d4c-fb35-4117-a5a0-673197e79b72 | Mucositis is caused by: | 5-Fluorouracil | Methotrexate | Paclitaxel | Cisplatin | 0a | single | Flurouracil is used mainly for solid malignancies,i.e colon, rectum, pancreas, liver, urinary bladder, head, and neck. Genetic deficiency of dihydropyridine dehydrogenase(DPD) leads to Fluorouracil toxicity. Major toxicity is myelosuppression, mucositis, diarrhea, nausea, vomiting, peripheral neuropathy (hand-foot synd... | Pharmacology | Other topics and Adverse effects |
b39016d6-d5f1-4498-bef3-37d4eec914d7 | Complications of therapy with radioactive iodine includes - | Thyroid malignancy | Hypothyroidism | Leukemia | All | 1b | multi | Ans. is 'b' i.e. Hypothyroidism | Surgery | null |
f8bbd265-100a-4cda-9ec7-c1e9f4dafc0a | Uterine souffle : | Is a soft blowing murmur synchronous with foetal hea sounds | Is due to increase in blood flow through the dilated uterine vessels | Is due to the active foetal movements | Indicates the underlying foetal distress | 1b | single | Ans. is b i.e. Is due to increase in blood flow through the dilated uterine vessels Uterine souffle is a soft blowing systolic murmur The sound is synchronous with maternal pulse It is due to increase in blood flow through the dilated uterine vessels Heard low down at the sides of the uterus, best on the left side It c... | Gynaecology & Obstetrics | null |
d84bbbff-2835-4d0a-bd1f-2b8ee74e126c | Investigation of choice in bronchiectasis is | Bronchoscopy | MRI thorax | HRCT lung | Chest X-ray | 2c | single | HRCT chest is more specific for bronchiectasis and is the imaging modality of choice for confirming the diagnosis.CT findings include airway dilation(detected as parallel "tram tracks" or as the "signet-ring sign"-a cross sectional area of the airway with a diameter at least 1.5 times that of the adjacent vessel),lack ... | Medicine | Respiratory system |
cdc0bbbc-6b84-4ff4-927d-4641d2b07d58 | Nyctalopia is due to deficiency of | Vitamin A | Vitamin B | Vitamin C | Vitamin E | 0a | single | null | Biochemistry | null |
5287cf4d-ca07-40e0-b32a-81ebe7c460b8 | False about hepatic adenoma- | Benign lesion | OCP use | Older females | Cold on isotopescan | 2c | multi | Ans. is 'c' i.e., Older females o Hepatic adenomas are benign solid neoplasms of liver.MC seen in younger females (20-40 years of age)Usually solitaryRisk factor - Prior/current use of estrogens (OCP)o Clinical FeaturesPatients usually present with upper abdominal pain.Physical examinated is usually unrevealing,o Micro... | Surgery | Hepatic Tumors, Cysts, and Abscesses |
f9305a4e-40ad-41fa-8be2-3fe7dc212bfa | Renal threshold for serum glucose level- | 100 mg/dl | 200 mg/dl | 300 mg/dl | 400 mg/dl | 1b | single | Ans. is 'b' i.e., 200 mg/dl * The transport maximum for glucose is 375 mg/min whereas the filtered load of glucose is only 125 mg/min.* Therefore, in normal conditions 100% of glucose is reabsorbed in proximal tubules.* When plasma glucose concentration is 100 mg/dl the filtered load is at its normal level, 125 mg/min,... | Physiology | Kidneys and Body Fluids |
65f2ce5a-dd89-45fc-a2cd-5f369acffe77 | A 9-year-old boy diagnosed as uncomplicated pulmonary tuberculosis. He is put on isoniazid, rifampin, and ethambutol at home after initial treatment given at hospital. Which is accurate statement for this scenario? | His 3-year-old sibling should receive INH prophylaxis | A baseline test of auditory function test is essential before drug treatment is initiated | Polyahralgia is a potential adverse effect of the drugs the boy is taking | His mother, who takes care of him, does not need INH prophylaxis | 0a | multi | Prophylaxis with INH is always advisable for family members and close contacts in active cases. None of the drugs prescribed is associated with nephrotoxicity. Polyahralgia is a side effect of pyrazinamide that's not given in this case. Routine LFTs should be done in younger patients if INH plus rifampin given in highe... | Pharmacology | Mycobacterial Diseases (TB, Leprosy and MAC) |
47d1dbea-e18b-4ece-8462-61a575298168 | How much luting agent is required for cementation of crown? | 3/4th filled slightly upto the margin | 1/4th filled | 1/2 filled | Full to prevent bubble | 2c | single | null | Dental | null |
7e4ff08e-29c7-47d1-9239-f79e6e0595d0 | Functional unit of muscle: | Sarcomere | Actin | Myosin | Troponin | 0a | single | Functional unit of muscle is : sarcomere It is the pa of myofibril present between two succsive z lines. Ref: Guyton and Hall textbook of medical physiology 12th edition, page number:86,87 | Physiology | Cardiovascular system |
86281c8e-6384-4402-aa3a-80420e029ef0 | Cause of exudative retinal detachment are: | Scleritis | Toxaemia of pregnancy | Central serous retinopathy | All | 3d | multi | Ans. All | Ophthalmology | null |
4d147d09-ab73-40ed-814e-379b8d4df231 | A 47-year-old man suddenly develops high fever and hypotension. He has a generalized erythematous macular rash, and over the next day, develops gangrene of his left leg. Which of the following is the most likely organism? | Corynebacterium diphtheriae | Streptococcus group C | Neisseria gonorrhoeae | Streptococcus group A | 3d | single | Streptococcus group A can cause a toxic shock-like syndrome, and has been increasing in frequency in North America. Streptococcal toxic shock-like syndrome was so named because of its similarity to staphylococcal toxic shock syndrome. The illness includes fever, hypotension, renal impairment, and the respiratory distre... | Medicine | Infection |
197f4476-5229-44a6-b9fb-813967c23cfc | In amyloidosis of the tongue, the amyloid is deposited primarily in the: | Stromal connective tissue | Cells of the surface epithelium | Nuclei of the striated muscle cells | Cytoplasm of the striated muscle cells | 0a | single | null | Pathology | null |
37585fbd-5eda-48c4-8b39-761335c90b6e | Which of the following is the most common cause of emergency depament visit related to LSD and its related substances? | Bad trip | Flashbacks | Synaesthesia | Papillary dilatation | 0a | single | The most frequent acute medical emergency associated with LSD use is a panic episode (the "bad trip"), which may persist up to 24 h.A trip is a period of intoxication from a hallucinogenic drug, such as lysergic acid (LSD) or magic mushrooms (psilocybin). It is called a trip because perceptions of the world change so d... | Microbiology | All India exam |
9f5413a7-dacf-4629-94f5-0e1ecc12dfbf | Bilateral destruction of auditory cortex in man causes | Almost total deafness | Hearing defect for higher frequency sounds | Deficiency in interpretation of sounds | Inability for the orientation of sounds | 2c | single | (C) Deficiency in interpretation of sounds # Lesion of auditory cortex leads to loss of recognition of total patterns with loss of analysis of properties of sound and sound localisation.> Thus lesion of auditory cortex leads to defect in interpretation of sounds. | Physiology | Special Senses: Hearing and Equilibrium |
db51ede8-e2b6-4637-9ff2-bc6efb98d662 | The following infection resembles malignancy - | Echinococcus granulosus | E. multilocularis | E.vogeli | E. oligarthus | 1b | single | Ans. is 4b' i.e., E. multilocularis o The chief character of E. multilocularis cyst is its tendency to proliferate, thereby resembling a neoplasm.Hydatid disease of liver is caused byo Echinococcus granulosuso Echinococcus multiloculariso Echinococcus vogeli- Unilocular cystic lesions- Multi locular alveolar hydatid cy... | Microbiology | Parasitology |
fc4ad074-28fe-4b8f-bde1-79c50dadad98 | A 1 year old child is brought to you with delayed milestones. On examination you note that the child is very fair with hypopigmented hair and blue eye. He has also got eczemas. The child was also very irritable. What is your diagnosis? | Albinism | Phenylketonuria | Alkaptonuria | Cystinosis | 1b | single | This child is suffering from Phenylketonuria. Here there is inability to conve phenylalanine to tyrosine due to phenylalanine hydroxylase deficiency. The decreased pigmentation in this condition is due to reduced melanin formation. The treatment is a diet low in phenylalanine with tyrosine supplementation. Delay in ini... | Pediatrics | null |
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