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135
583121fc-95c1-4e8a-bd7d-f80f1d223566
Scar endometriosis can occur following :
Classical Cesarean Section
Hysterotomy
Episiotomy
All of the above
3d
multi
Ans. is d i.e. All of the above Endometriosis sometimes occurs in abdominal wall scars following operations on uterus or tubes and is known as Scar endometriosis. Operations most likely to be followed by scar endometriosis Hysterotomydeg * Classical cesarean sectiondeg Myomectomydeg * Ventrofixationdeg Following operat...
Gynaecology & Obstetrics
null
846be67d-4d7b-4eea-b950-c81d2fd17e08
Which of the following is the most common predisposing factor for placenta accreta?
Myomectomy
Recent curettage
Previous cesarean section
Placenta pre
3d
single
Placenta accreta is the attachment of placenta directly to the myometrium without any intervening decidua basalis Impoant risk factor : * Placenta pre ( most common ) * Prior cesarean section
Gynaecology & Obstetrics
Placenta - Types and their complications
c57f9567-484b-45ce-b570-a2e35abbdbe9
What is the best characterizes of the sinusoids
Have smaller diameter than lymph capillaries
Are not found in skeletal muscle
Have a continuous endothelial lining
Have a continuous basement membrane
1b
multi
sinusoids - In some tissues the 'exchange' network is made up of vessels that are somewhat different from capillaries, and are called sinusoids. Sinusoids are found typically in organs that are made up of cords or plates of cells. These include the liver, the adrenal coex, the hypophysis cerebri, and the parathyroid gl...
Anatomy
General anatomy
de51cebe-a745-4538-ab7c-e066f4c0b07f
The chest CXR of patient shows?
Emphysema
Reticular shadows
Batwing edema
Kerley B lines
1b
single
CXR shows the presence of reticular nodular shadows in both lung fields. Choice A is ruled out since emphysema shows hyperinflation with flattening of the diaphragm. Choice C and D are associated with increased CT ratio and cardiac borders can be ruled out. Hence answer by exclusion is choice B
Medicine
Interstitial Lung Disease
c8dd1209-766f-4901-8ec0-6a83d54510d9
Elschnig&;s pearls are a sign of
Secondary cataract
Cystoid macular oedema
Chronic uveitis
All of the above
0a
multi
After cataract It is also known as 'secondary cataract'. It is the opacity which persists or develops after extracapsular lens extraction. Causes: (i) Residual opaque lens matter may persist as after cataract when it is imprisoned between the remains of the anterior and posterior capsule, surrounded by fibrin (followin...
Ophthalmology
Lens
5954e5fb-b9c6-4e0b-836f-5dd56503a6cb
Regarding urinary bladder stone one is Not true ?
Common in Paediatric pt in tropics than that of non tropical areas
Uric acid stones are dropped from above
Jack stone is due to urea splitting bacteria
Commonly distal passage obstruction cause stone
1b
multi
Answer is 'b' i.e. Uric acid stones are dropped from above It is the oxalate stones that are usually dropped from above (i.e. formed in the kidney and dropped in the bladder through ureter). Uric acid stones are mostly formed within the bladder. In general most of the bladder calculi are formed within the bladder itsel...
Surgery
null
7b660d57-98de-454d-aa47-292b265f3ec2
A 13 year old boy has bilateral gynecomastia. i is height is 148 cm, weight 58 kg; the sexual maturity rating is stage 2. The gynecomastia is most likely due to –
Prolactinoma
Testicular tumour
Pubertal gynecomastia
Chronic liver disease
2c
single
null
Pediatrics
null
edda2042-4ce7-49bf-8b78-c128ba93381d
Following is used to stain fungi
PAS
Fontana stain
Ferrous trichrome
Pearls prussian blue
0a
single
null
Pathology
null
2fb7dc3b-1c9c-4523-81e5-f638a6d60476
Fluoresciene stain is used in the eye to stain ?
Cornea
Retina
Choroid
Iris
0a
single
Ans. is 'a' i.e., Cornea Impoant corneal examinations Keratometry, Corneal topography Specular microscopy Slit lamp Pachymeter Placido's disc Fluorescein, Alacian blue & Bengal rose stain Window reflex, slit lamp biomicroscopy, Placidos' disc Used for Curvature of cornea Corneal endothelial density Corneal opacity Thic...
Ophthalmology
null
0b024109-b675-4d63-aa96-6594b245f35f
Hea failure cells are -
Lipofuscin granules in cardiac cells
Pigmented alveolar macrophages
Pigmented pancreatic acinar cells
Pigment cells seen in liver
1b
single
Ans. is `b' i.e., Pigmented alveolar macrophageso Hea failure cells (siderophages) are hemosiderin containing macrophages in alveoli that are seen in left ventricular failure and denote previous episodes of pulmonary edema.Left sided hea failure o The major morphological and clinical effects of LVF are due increased ba...
Pathology
null
c333ea69-4004-464a-8b28-8ad492afc746
Submental lymph nodes drains from -
Centre of lower lips
Posterior 1 /3 of tongue
Anterior 2/3 of tongue
Angle of mouth
0a
single
Ans. is 'a' i.e., Centre of lower lips Submental lymph nodeso These lymph nodes lie on the mylohyoid in the submental triangle. The receive afferents from superficial tissue below chin, central part of lower lip, adjoining gums, anterior part of the floor of the mouth and tip of the tongue. These nodes, themselves, dra...
Anatomy
Oral Cavity & Tongue
a65c561a-3316-49be-bd2d-1a624d03bf8c
Amoebic liver abscess most commonly affects -
Right lobe of liver
Left lobe of liver
Portal vein
Right pleural cavity
0a
single
Ans. is 'a' i.e., Right lobe of liver Amoebic Liver abscesso Caused by Entamoeba histolytica whose cysts are acquired through the feco-oral route and their trophozoites reach the liver through portal venous systemo Like pyogenic abscess they are also common in rt. lobe of livero Clinical Picture# the typical clinical p...
Surgery
Hepatic Tumors, Cysts, and Abscesses
4d94fb8f-f3be-4392-a555-2256015f61d4
Apple-jelly nodules is/are seen in:
Lupus vulgaris
DLE
Lichen planus
Psoriasis
0a
single
Ans: A (Lupus vulgaris) Apple jelly nodules:characterized by yellow-brown nodules with tiny darker granules. On probing, the noduies are soft jelly-like"- Neena Khanna 3rd/217Lupus Vulgaris Neena Khanna 3rd/217MorphologySingle (or few) lesions.Well demarcated, annular or arcuate plaques which slowly extend centrifugall...
Skin
C. Mycobacteria
72f2d5c0-9419-4fc5-a396-b8316e5d68ee
Both PT and APTT are prolonged in -
Factor II deficiency
Thrombocytopenia
Factor VII deficiency
Heparin therapy
0a
multi
Ans. is 'a' i.e., Factor II deficiencyo Prolongation of both PT and A PPT is typically seen in deficiency of involoved in the common pathway, namely factor //, factor V and factor X (and fibrinogen).o Heparin in clinical concentrations is typically associated with isolated prolongation of APTT while PT is normal be cau...
Medicine
Bleeding and Thrombotic Disorders
b205e045-f3af-4dc9-9049-d348a22b1c87
Fejereskov and Thylstrup index is used for
Caries Index in primary teeth
Index to measure Fluorosis
Gingival Bleeding Index
Periodontal Index
1b
single
null
Dental
null
a875ff74-4138-4641-816c-c1037cecf34d
At which level the somites initially form-
Thoracic level
Cervical level
Lumbar level
Sacral level
1b
multi
The first pair of somites develop a short distance posterior to the cranial end of the notochord, and the rest of the somites from caudally.
Anatomy
null
3c621a20-423a-48e1-ba8f-bf4d4759fce5
An infant has papulovesicular lesions on palms, soles, face and trunk. The diagnosis would he
Scabies
Atopic dermatitis
Uicaria
Seborrhoic dermatitis
0a
single
Ans. a. Scabies Scabies: Primary lesions are of three types:Q Burrow: Serpentine (S-shaped) path traversed by parasite in stratum corneumQ. It is pathognomic of lesion. Papules and papulovesicles: Due to hypersensitivityto the mite Fine pin head size follicular papules Scalp, face, palms and soles are characteristicall...
Skin
null
167efc54-fa4d-4d2c-904b-b36cf7040875
Blood supply of femoral head is:
Femoral aery
Obturator aery
Internal pudendal aery
All
1b
multi
B i.e. Obturator aery
Anatomy
null
2bf471cf-6bce-4665-bffa-7e06e131c2e6
Hyperpolarization is due to
Influx of chlorine
Influx of potassium
Influx of sodium
All
0a
multi
In hyperpolarization the membrane becomes more negative It is due to continued potassium efflux or chloride ion influx. Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:67,68,69
Anatomy
General anatomy
fd61091f-97e0-4d50-9ea4-9f325c7f662b
Which of the following cancer makes up the majority in reproductive tract neoplasms during pregnancy?
Vaginal
Cervical
Uterine
Ovarian
1b
single
Cancer in the reproductive tract may also complicate pregnancy and of these cervical neoplasia makes up the majority.Cervical > Ovary > Uterus, Vulva or Vagina(Ref: William's Obstetrics; 25th edition)
Gynaecology & Obstetrics
All India exam
5d9a0623-6ec1-4dc5-bf90-8b6e0b42049f
Resistance to acyclovir is most commonly due to mutation in a viral gene that encodes a protein that:
Conves viral RNA into DNA
Phosphorylates acyclovir
transpos acyclovir into the cell
Transpos acyclovir out of the cell
1b
single
(Ref: KDT 6/e p768) Nucleoside/tide analogues (like acyclovir) act by conveing to NTPs. First phosphorylation step occurs inside the virs and resistance occurs if there is mutation in this gene.
Pharmacology
Other topics and Adverse effects
f74bef4a-c236-4fa2-8e13-13faa3e3b47f
Which of the following stages of gypsum expansion shows initial crystal growth?
I
II
III
IV
1b
single
Imagine that the initial mix is represented in the figure (stage I) by the three round particles of hemihydrate surrounded by water. Under normal setting conditions, the crystals of the dihydrate begin to form on the nuclei. The water around the particles is reduced by hydration and these particles are drawn more close...
Dental
null
923fbe25-caa5-4388-9465-63b9133a416c
In neonates, spinal cord ends at:March 2010 and 2012, March 2013
L1
L2
L3
L4
2c
single
Ans. C: L3
Anatomy
null
f2a070f5-c219-4479-b9df-acf2ca2123e3
Which of the following is the most important interaction in the formation of cell membrane lipid bilayer and in lipid-protein interaction?
Hydrophobic interactions
Both hydrophobic and convalent interactions
Covalent bonds
Hydrogen bonds
0a
multi
Interactions in the cell membrane. -        Hydrophobic (most important)– Between lipids- Information of lipid bilayer​ Transmembrane proteins and lipids -        Van der walls interaction Between lipids- Information of lipid bilayer​ Transmembrane proteins and lipids -        Electrostatic bonds Between transmemb...
Physiology
null
19383a25-6995-4415-a34b-7e5ae4da4563
Spot the diagnosis in the following IVU
Horse shoe kidney
Bladder diveiculum
Pelvic mass
Ectopic kidney
3d
single
Note the ectopic kidney seen in the pelvis on left side above the urinary bladder. This patient had solitary right kidney, which was normal in position. Ectopic kidneys are found in one in 1000 people, usually on the left near the pelvic brim. The other kidney is generally normal. A diseased ectopic kidney may present ...
Radiology
Genitourinary radiology
c6d037fd-bbc7-43b4-a3ef-bf05ce9c4eab
Which of the following is true regarding the principle of use of MRCP
Intra liminal dye is used to create the three dimension view of the structures
Dye is instilled percutaneously first then MRI is used
Use of heavily T2-weighted image without contrast to create the three dimensional image of the biliary tree using MIP algorithm
Use of systemic Gadolinium as a contrast agent to create the three dimensional image of the biliary tree
2c
multi
MRI cholangiography and MRI cholangiopancreaticography (MRCP) are imaging techniques used to evaluate the biliary system. Heavily T2- weighted images are used to provide an overview of the biliary system and pancreatic duct Excellent diagnostic - quality images are obtainable, with high sensitivity and specificity for ...
Anatomy
G.I.T
9a05da9b-02ba-4a30-a5e2-2d5cb2298df4
A 5 years old boy presents with hepatomegaly, hypoglycaemia, ketosis. The diagnosis is:
Mucopolysaccharidosis
Glycogen storage disorder
Lipopolysaccharidosis
Diabetes mellitus
1b
single
Ans. B. Glycogen Storage Disorder(Ref: Nelson 20e Chapter 715 Defects in metabolism of Carbohydrates)Patients with type IGSD may present in the neonatal period with hypoglycemia and lactic acidosisThese children often have doll-like faces with fat cheeks, relatively thin extremities, short stature, and a protuberant ab...
Biochemistry
Carbohydrates
dce8de49-8525-4e50-a17c-4e770c840a87
Early fusion of coronal suture along with other skull sutures is seen in:
Brachycephaly
Oxycephaly
Trigonocephaly
Scapocephaly
1b
single
Premature closure of the coronal suture results in a ahigh, tower-like cranium, called oxycephaly or turricephaly. It is more common in females.
Anatomy
null
855cf896-4f81-4f71-94ba-c5076d3ba405
In Hanup's disease, the following amino acids are excreted into the urine
Basic amino acids
Acidic amino acids
Neutral amino acids
Hydrophilic aminoacids
2c
single
Hanup disease reflects impaired intestinal and renal transpo of tryptophan and other neutral amino acids.The defect limits tryptophan availability for niacin biosynthesis and accounts for the pellagra-like signs and symptomsHarper 30th edition Pg: 308
Biochemistry
Metabolism of protein and amino acid
985953c7-eb82-4a46-9205-5d5e86a2c3f3
The contribution of operation of sodium potassium electrogenic pump for the development of net -90 millivolt on resting membrane potential is
-4 millivolt
-80 millivolt
-70 millivolt
+4 millivolt
0a
single
null
Surgery
null
86e0203a-807c-46ee-aa01-8769ac31c285
Malleus and Incus are derived from?
First arch
Second arch
Third arch
Fouh arch
0a
multi
A i.e. First arch
Anatomy
null
db773618-4e3a-4c1a-b2d2-8da77cb74621
Which of the following is known to cause Pedal Botryomycosis -
Actinomyces somaliensis
Nocardia asteroides
Staphylococcus aureus
All of the above
2c
multi
null
Microbiology
null
1a75f21b-fae8-4c17-b4a1-732899826a80
A farmer is found convulsing in the farm. Diarrhea, sweating and urination are apparent. Pupils are pin point. Drug poisoning is suspected. Most probable cause is:
Acetaminophen overdose
Amphetamine toxicity
Organophosphate poisoning
Atropine poisoning
2c
single
Ans. C. Organophosphate poisoningThese are characteristic features of anti-cholinesterase (organophosphate and carbamate) poisoning.A. Symptom due to muscarinic actions: (DUMBELS)* Diarrhoea, Diaphoresis* Urination* Miosis* Bronchoconstriction* Excitation CNS* Lacrimation,* SalivationB. Symptom due to nicotinic action:...
Pharmacology
Anaesthesia
bcd2bd64-68a5-437f-a0e4-1990576cf211
In post-ductal coarctation of aoa, collaterals may be formed by which of the following:
Veebral aery
Suprascapular aery
Subscapular aery
None
3d
multi
Suprascapular aery, Subscapular aery, Posterior intercostal aery and Veebral Aery may all form channels for collateral ciculation in coarctation of aoa. The veebral aery is probably the least prominent pathway for collateral circulation amongst the options provided and hence may be accepted as the single best answer by...
Anatomy
null
b0fa4358-b1d3-4405-8b29-2c0dab66816c
Which enzymatic mutation is responsible for immortaity of cancer cells
DNA reverse transcipatase
RNA polymerase
Telomerase
DNA polymerase
2c
single
Prevention of telomere shortening with every cell division, due to activity of telomerase is the cause of immortality in cancer cells, germ cells, and stem cells as it protects from cellular aging and apoptosis.
Biochemistry
null
eaa79ce5-2cda-4404-9c7e-4aa7176a8cb6
Because of an inflammatory bowel disease (Crohn's disease) and a small bowel obstruction leading to bowel ischemia, an elderly woman requires bypass of her ileum and jejunum and is scheduled for a gastrocolostomy. The surgeon will ligate all aeries that send branches to the stomach. Which of the following aeries may be...
Splenic aery
Gastroduodenal aery
Inferior pancreaticoduodenal aery
Left gastroepiploic aery
2c
multi
The inferior pancreaticoduodenal aery does not supply the stomach. All the other aeries supply the stomach.
Anatomy
Stomach and aerial supply of abdomen
18817371-aae2-4e83-9db8-732b06531d7a
Multiple drug resistance is transferred through -
Transduction
Transformation
Conjugation
Mutation
2c
single
Ans. is 'c' i.e., Conjugation Resistance to multiple drugs is transmitted by R factor (plasmid) o R factor is transferred from one bacterium to other by conjugation. o Transduction and mutation usually cause resistance to one drug. o Transformation is not involved significantly in drug resistance.
Pharmacology
null
fa2e5107-26ee-487d-97a7-7a957e4a5eca
Which line of death ceificate represent major antecedent cause of death -
Ia
Ib
Ic
II
2c
single
Ans. is 'c' i.e., Ic International death ceificate The basis of moality data is death ceificate. For ensuring national and international comparability, it is necessary to have a uniform and standardized system of recording and classifying deaths. For this purpose WHO has recommended international death ceificate. Consi...
Social & Preventive Medicine
null
52854007-73d3-45e5-9b38-ef30cda2723a
Which of the following is not associated with mucous secretion?
Paneth cell
Goblet cell
Brunner's glands
Crypts of Lieberkuhn
0a
single
Panthet cells are not associated with mucous secretion, it secretes lysozyme and also has some phagocytic functions. Goblet cells are specialized mucus secreting cells present throughout the intestine. Brunners glands are found in the submucosa of small intestine, they produce viscid, mucoid, alkaline secretion which n...
Physiology
null
dcc3c697-23eb-4dca-bfdc-4d3c3f35115f
Which of the following cranial nerves do not carry parasympathetic outflow
Occulomotor
Trochlear
Facial
Glossopharyngeal
1b
single
Parasympathetic cranial nerves are 3-occulomotor 7-facial 9-glossopharyngeal 10-vagus Refer kDT 7/e p78
Pharmacology
Autonomic nervous system
697a4432-84aa-49fc-9be9-52f7f71abfc4
Which is not given in anaphylactic reaction?
Epinephrine
Anti-histamine
Blood transfusion
Beta-adrenergic agonists
2c
single
null
Pharmacology
null
da2e7620-e32d-4298-b5bd-eb6f5b5e1908
A hospitalized patient has an ejection fraction of 0.4, a hea rate of 95 beats/min, and a cardiac output of 3.5 L/min. What is the patient's end-diastolic volume?
14 mL
37 mL
55 mL
92 mL
3d
single
First, calculate stroke volume from the cardiac output and hea rate: Cardiac output = stroke volume x hea rate; thus, stroke volume = cardiac output/ hea rate = 3500 mL/95 beats/min = 36.8 mL. Then, calculate end-diastolic volume from stroke volume and ejection fraction: Ejection fraction = stroke volume/end-diastolic ...
Physiology
Cardiac Output
9e758ccb-3bcc-461d-a31b-0feb910ee961
Phantom limb is an example of disorder of:
Thought
Perception
Cognition
None of the above
1b
multi
Perception is defined as any information which is perceived through sensory organs In phantom limb, the patient feels sensations in the amputated limb which in reality is not present. Hence, it's a disorder of perception.
Psychiatry
Basics of Psychiatry
9011e96e-d8d9-481d-9847-19b48c8f7466
The most common prescription medication for sialorrhea
Glycopyrrolate
Atropine sulphate
Scopolamine
Amitriptyline
0a
single
Traditional medications for the treatment of drooling target the reduction of saliva production using anticholin- ergic mechanisms. While they will reduce salivary output, they do not treat the underlying neuromuscular problems, so some patients may find the anticholinergic side effects out - weigh the benefit of the d...
Pathology
null
6091e027-b401-4a86-9fd3-164e480ca485
True about Measles rash appearance:
Along with Koplik spots
1-2 days before Koplik spots
1-2 days after Koplik spots
Post measles stage
2c
multi
RASH IN MEASLES Stas 12-24 hours after appearance of Koplik spots. Retro -auricular origin spreads to other pas of body (fades in opposite direction). Takes 1 - 2 days to cover body * Fever is highest and patient is sickest on day of rash.
Social & Preventive Medicine
Respiratory Infections
2a07a02a-45c3-4d00-87b9-09165148e4ad
Grading disease severity as mild, moderate, severe is an example of which scale?
Nominal
Ordinal
Interval
Ratio
1b
single
There are characteristics that should be measured in terms of quantities but nonavailability of a good instrument compels measure in terms of what is called an ordinal scale. Example is disease severity measured as mild, moderate or severe. Ref: Medical biostatistics, 1st edition pg: 99
Social & Preventive Medicine
null
1040818c-4093-449d-b4ad-a2445c4e7a2d
Which of the following antitubercular drugs is not hepatotoxic
Isoniazid
Rifampicin
Ethionamide
Streptomycin
3d
single
Refer KDT 6/e p743 Streptomycin and Ethambutol are not hepatotoxic Read carefully option (c) is Ethionamide AMD not Ethambutol
Pharmacology
Chemotherapy
32b366a1-fb34-4016-a2c1-3d52381cb5e7
Landau-Kleffner syndrome is characterized by all of following except
Seizure
Loss of language skill
Normal EEG during sleep
Normal brain CT scan
2c
multi
Ans. C. Normal EEG during sleep Ref : Nelson Textbook of Pediatrics 20th/ed p2837ExplanationLandau-Kleffner syndrome is a condition of unknown cause characterized by:# Loss of language skills attributed to auditory agnosia in a previously normal child# Seizures (focal, generalized tonic-clonic, atypical absence, partia...
Pediatrics
Central Nervous System
8a6cd863-7239-4364-922a-4a22f0f71904
Nicotinic acid ?
Increases HDL
Increased triglyceride synthesis
Type II hyperlipoproteinemia
Decreased hydrolysis of VLDL
0a
single
Ans. is 'a' i.e., Increases HDL Nicotinic acid (Niacin) There arc three main type of lipases related to metabolism of lipoproteins ? Lipoprotein lipase - Present in blood vessels and causes hydrolysis of tryglyceride content of VLDL and chylomicrones. Hepatic lipase - Conves IDL to LDL by hydrolysing the triglyceride c...
Pharmacology
null
d779bcc8-f9ab-4bf5-a78c-84693308e74a
Circulus aeriosus iridis major is formed by the anastomosis of
Long posterior ciliary aeries with sho posterior ciliary aeries
Long posterior ciliary aeries with anterior conjunctival aeries
Long posterior ciliary aeries with anterior ciliary aeries
Anterior ciliary aeries with sho posterior ciliary aeries
2c
single
Anterior ciliary aeries: These are derived from the muscular branches of ophthalmic aery. These aeries pass anteriorly in the episclera, give branches to sclera, limbus and conjunctiva; and ultimately pierce the sclera near the limbus to enter the ciliary muscle; where they anastomose with the two long posterior ciliar...
Ophthalmology
Anatomy, Development and clinical examination
d5210d12-6dda-4a4c-b9c2-cd2d934a4118
A 20 year old patient presents with syncope. His current ECG is shown below. His elder brother had died suddenly while watching television. The patient was given Cardioversion and subsequent cardiac MRI revealed fibro-fatty changes in RV myocardium. What is the diagnosis of this patient?
Hyperophic obstructive Cardiomyopathy
Arythmogenic RV dysplasia
Brugada syndrome
Tako- Tsubo Cardiomyopathy
1b
single
Arythmogenic RV dysplasia(ARVD) ECG shows HR of 300/min with broad complex tachycardia. Variation in amplitude of QRS complexes which indicates a diagnosis of polymorphic Ventricular Tachycardia. In acute setting DC shock 200 J Biphasic should be given. The Cardiac MRI repo showing fibro-fatty changes in RV myocardium ...
Medicine
ECG and Arrhythmias 1
22285557-454d-4537-8d8b-096ccaad4c38
Most common phase I biotransformation reaction is?
Oxidation
Hydrolysis
Cyclisation
Reduction
0a
single
Ans. is 'a' i.e., Oxidation Oxidation is the most impoant metabolizing reaction.
Pharmacology
null
00d2ec9a-b4a0-4e1f-8806-b30803ad4bd3
Sulfasalazine is used in -
Ulcerative colitis
Osteoarthritis
Gouty arthritis
Irritable bowel syndrome
0a
single
Ans. is 'a' i.e., Ulcerative colitis Inflammatory bowel disease (crohn's disease & ulcerative colitis)o 5-aminosalicylic acid (5-ASA) is the main anti-inflammatory compound that acts locally in colon. It is the first line of treatment in mild to moderate UC and CD. When given alone 5-ASA is absorbed > 80% in proximal i...
Pharmacology
G.I.T
5e6eadec-afaf-47d1-b8c6-259852f3d548
Kaposi sarcoma is caused by: March 2013
HHV 6
HHV 7
HHV 8
All of the above
2c
multi
Ans. C i.e. HHV 8 Kaposi sarcoma (KS) It is a tumor caused by Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV). It was originally described by Moritz Kaposi , a Hungarian dermatologist practicing at the University of Vienna in 1872. It became more widely known as one of the AIDS-de...
Microbiology
null
c0b26902-473a-4579-9674-20a9aef5ab3d
All of the following are examples of microdeletion syndromes, EXCEPT:
Wilms' tumor-aniridia complex
Miller Dieker syndrome
Velocardiofacial syndrome
None of the above
3d
multi
The term contiguous gene syndrome refers to genetic disorders that mimic a combination of single-gene disorders. They result from the deletion of a small number of tightly clustered genes. Because some are too small to be detected cytogenetically, they are termed microdeletions. The application of molecular techniques ...
Medicine
null
a9d6a4df-029e-4955-bf03-388dc4580f0b
All are true for PTSD except
Hippocampus & amygdala
Anhedonia
Depression and quilt
Anxiolytic is treatment of choice
3d
multi
D i.e. Anxiolytic is treatment of choice
Psychiatry
null
114a81b1-9922-4108-84e7-9fcac92978f2
Which of the following is true regarding Pneumothorax?
May occur in asthma patient
Pleuritic chest pain may be present
Decreased breath sounds
All the above
3d
multi
Spontaneous pneumothorax in most patients occurs from the rupture of blebs and bullae. Primary spontaneous pneumothorax (PSP) is typically observed in tall, young people without parenchymal lung disease and is thought to be related to increased shear forces in the apex. Secondary spontaneous pneumothoraces (SSP) occur ...
Medicine
null
66b83499-305c-4995-9dda-1d73d559451d
'Herald patch' is seen in:
Pityriasis rosea
Pityriasis rubra pilaris
Pityriasis lichenoides et varioliformis acuta
Pityriasis alba
0a
single
Ans. A. Pityriasis rosea. (Ref. Harrison's 18lh/pg. 367)In Pityriasis rosea, initially, there is a single 2- to 6-cm annular salmon-colored patch (herald patch) with a peripheral rim of scale, followed in days to weeks by a generalized eruption involving the trunk and proximal extremities.Pityriasis rosea:# It is an ac...
Skin
Papulosquamous Disorders
af398a68-b91e-4911-a7c2-fe1228b53042
Common fungus causing corneal ulcer -a) Aspergillusb) Mucorc) Fusariumd) Sprothrix
a
bc
ad
ac
3d
single
null
Microbiology
null
abd22ebe-9179-43ca-b09c-8fdb4d8bf4f6
A 34-year-old man is brought to the emergency room by his family because of extreme lethargy. After further questioning, he admits to taking a large number of phenobarbital tablets. Which of the following is the most appropriate next step in management?
acidification of urine to pH 3.0
repetitive administration of activated charcoal
ipecac to induce vomiting
hemoperfusion
1b
multi
Activated charcoal absorbs barbiturates very effectively and is useful in decontamination of the GI tract. Renal elimination of phenobarbital is enhanced by alkalinization of the urine to a pH of 8 with sodium bicarbonate and fluids. Hemodialysis and hemoperfusion are reserved for extreme cases with refracting hypotens...
Medicine
Miscellaneous
1eec3dab-7c27-4682-b67a-622efaa6eac9
Degree of freedom for 2/2 contingency table is?
1
Zero
2
4
0a
single
Ref: Parks 23rd edition Degree of freedom = (r-1)(c-1) =(2-1)(2-1)= 1
Social & Preventive Medicine
Biostatistics
051b8b6f-020c-426b-8a19-623e0ba582a2
Most common cause of lobar hemorrhage in the elderly
Coagulopathy
Aneurysm
Amyloid angiopathy
Trauma
2c
single
Answer- C. Amyloid angiopathyLobar intracerebral hemorrhage is bleeding in the largest pa of the brain called the cerebrum.Intracerebral hemorrhage are attributed to hypeensive vasculopathy in small penetrating brain aeries and subcoical vessels in patients with amyloid angiopathy.Amyloid angiopathn a chronic depositio...
Medicine
null
c072acce-9fbe-4bde-bfc5-0f4b8da4cb72
Which of the following is not true about spasmodic dysphonia
Local laryngeal disorder
May be associated with other focal dysphonia
Patient with the abductor type have strained and strangled voice
Botulinum toxin is the standard treatment for it
0a
multi
SPASMODIC DYSPHONIA Spasmodic dysphonia is also called as laryngeal dysphonia. The condition is characterised by spasm of phonatory muscles. It is a neurological disorder and is of following types: (A) Adductor spasm (M/C):- Adductor muscles go into spasm lead ing to strained and strangled voice (scratchy creaky voice)...
ENT
Larynx
35c720cf-9c40-43a8-b936-e9b0f17f5878
Which of the following organism is biggest ?
Balantidium coli
Entamoeba coli
Escherichia coli
Entamoeba histolytica
0a
single
Ans. is 'a' i.e., Balantidium coli
Microbiology
null
81009b09-9466-4ba6-9bf4-87d0d79bd920
Drug producing haematological side effect is:
Nitrous oxide
Halothane
Ketamine
Sevoflurane
0a
single
Ans: A (Nitrous oxide) Ref: Ajax Yadav, Short Textbook of Anesthesia, 1st edition, pg 59.Explanation:Nitrous oxide produces Aplastic anemia and Megaloblastic anemiaNITROUS OXIDE (LAUGHING GAS)Stored as liquid in blue color cylinderE5 times more heavier than air35 times more soluble than nitrogenAnesthetic propertiesIt ...
Anaesthesia
Miscellaneous General Anesthesia
2139c14b-367c-41dc-85bb-8bd6ab36da77
A patient presents with endocrinopathy. fibrous dysplasia of bone and hyperpigmentation. What should be the possible diagnosis?
Ollier's syndrome
Mazabraud syndrome
Mc Cune-Albright syndrome
Maffucci's syndrome
2c
single
Mc Cune Albright syndrome is a triad of Precocious puberty (endocrinopathies) fibrous dysplasia, cafe-au-lait spots.
Pathology
null
2374249c-f96b-4f33-a825-a614587d5f71
Paneth cells characterized by
More number of lysosomal enzyme
High concentration of zinc
More concentration of EFR
Foamy cells
1b
single
Paneth cells are zinc-containing cells widely distributed in Lieberkuhn's crypts of small intestine in many species, but their function has remained obscure. Our previous study showed that a single intravenous injection of diphenylthiocarbazone (dithizone), a zinc chelator, forms zinc-dithizonate complexes in the cytop...
Pathology
G.I.T
184f084d-e54b-4886-bcf2-166829061f30
The following drug has significant drug interaction with the digoxin except
Cholestyramine
Thiazide diuretics
Quinidine
Amlodipine
3d
multi
Cholistyramine inhibits intestinal absorption of digoxin Thiazides result in hypokalemia and thus me precipitate digitalis toxicity by pharmacodynamic interaction Quinidine and verapamil reduces the excretion of digoxin and Thus may precipitate the toxicity(pharmakokinetic interaction) Refer kDT 6/e p499
Pharmacology
Cardiovascular system
70e42988-5271-46b9-9bd7-d1b7669c0694
Acute cholinesterase inhibitors intoxication include all of the following except
Salivation, sweating
Mydriasis
Bronchial constriction
Vomiting and diarrhea
1b
multi
Cholinesterase inhibitors have cholinomimetic actions. The major source of such intoxications is pesticide use in agriculture.The dominant initial signs are those of muscarinic excess: miosis, salivation, sweating, bronchial constriction, vomiting, and diarrhea. Central nervous system involvement (cognitive disturbance...
Pharmacology
Autonomic nervous system
4fabc0a1-0b39-44bc-bd47-df23f119fd29
Calcium is absorbed from:
Duodenum
Jejunum
Ileum
Colon
0a
single
All the divalent cations, except Mg++ , are absorbed from duodenum. Mg++ is absorbed from ileum. Calcium is absorbed mainly in duodenum and upper jejunum, not whole of jejunum.
Physiology
Gastrointestinal System
d8245966-fb0e-4aab-8c10-d60c6aa586e0
A 62-year-old childless woman noticed a blood-tinged vaginal discharge twice during the past month. Her last menstrual period was 10 years ago. Bimanual pelvic examination shows that the uterus is normal in size, with no palpable adnexal masses. There are no cervical erosions or masses. Her body mass index is 33. Her m...
Adenocarcinoma
Choriocarcinoma
Leiomyosarcoma
Malignant mullerian mixed tumor
0a
single
Postmenopausal vaginal bleeding is a red flag for endometrial carcinoma. Such carcinomas often arise in the setting of endometrial hyperplasia. Increased estrogenic stimulation is thought to drive this process, and risk factors include obesity, type 2 diabetes mellitus, hypertension, and infertility. Choriocarcinomas a...
Pathology
Female Genital Tract
9d861117-6c17-4302-8648-af97b7d78acd
Aquaporin deficiency cause?
Nephrogenic diabetes insipidus
Liddle syndrome
Baer syndrome
Gitelman syndrome
0a
single
1. Nephrogenic diabetes insipidus: Aquaporin 2" gene mutation impede the normal functionality of the kidney water channel, which results in the kidney being unable to absorb water. Autosomal recessivemanner. 2. Liddle syndrome: Gain of function of epithelial Na channel (ENaC) 3. Bater syndrome:- Defect in "Na-K-2Cl cot...
Medicine
NEET Jan 2020
6596667c-daff-4ad9-838f-1d7e370bf7d1
Sonographic criteria for diagnosing PCOD includes all except
Enlarged ovaries > 10mL
Presence of > 20 cysts in ovary
Cyst size 2 → 9 mm
Cysts in either one or both ovaries
1b
multi
Presence of 12 or more cysts on ultrasound is diagnostic of PCOD.
Gynaecology & Obstetrics
null
83fb5ffb-3d0c-4f8c-a55f-f5e819d2f37b
Letrozole belongs to which group?
SERM
SERD
LHRH analogues
Aromatse inhibitors
3d
single
Ans. is 'd' i.e., Aromatase inhibitors Aromatase inhibitorso Aromatase inhibitors are drugs which inhibit the enzyme Aromatase.o Aromatase is an enzyme responsible for the conversion of testosterone (androgens) to estrogens.o This conversion of androgens to estrogens occur in several tissues including ovary, adrenal co...
Pharmacology
Sex-Hormone
93f32b42-91e6-4a96-874d-79f0ebae9491
CAD predisposing factors-a) Homocysteinemiab) ↓ Lipoprotein Bc) ↑ Fibrinogend) ↑ HDLe) ↑ plasminogen activator inhibitors 1
acd
bde
cde
ace
3d
single
Homocysteine and Prothrombotic (↑ fibrinogen and ↑ plasminogen activator inhibitors) factors are emerging risk factors for atherosclerosis and coronary heart disease.
Pathology
null
61db1f3c-f8de-400b-9885-15e292e6f33d
Drug of choice for prophylaxis of acute mountain sickness is?
Diltiazem
Digoxin
Dexamethasone
Acetazolamide
3d
single
DOC for acute mountain sickness are Carbonic anhydrase inhibitors like Acetazolamide. BEST treatment is to descent down because it occurs due to decreased pO2 at high altitudes. DOC for motion sickness is Hyoscine.
Pharmacology
Kidney
2f831bc8-b2c6-47da-a76a-9ada20456324
In modern day obstetrics, most common cause of rupture uterus is -
Prolonged labour
Previous LSCS scar rupture
Forceps delivery
Internal podalic version
1b
single
Ans. is 'b' i.e., Previous LSCS scar rupture * Disruption in the continuity of all uterine layers: endometrium, myometrium and serosa anytime beyond 28 weeks of pregnancy is called rupture of uterus.Incidence* 1 in 2000 to 1 in 200 deliveries. Rupture uterus from obstructed labor is becoming less because of improved ob...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
24c0ce75-6e0e-47e2-aa9d-0c035ee63291
Which one of the following serum levels would help in distinguishing an acute liver disease from chronic liver disease -
minotransaminase
Alkaline phosphatase
Bilirubin
Albumin
3d
single
null
Medicine
null
fce84819-33a1-4d96-acc6-2a3124f92b68
Which of the following features are of naso alveolar cyst
An ovoid shaped radiolucency above the lateral incisor and canine teeth
Erosion of base above lateral incisor and canine teeth
An inverted funnel shaped radiolucent lesion above the roots of lateral incisor and canine teeth
A pear shaped radiolucent Lesion between roots of lateral incisor and canine teeth
1b
multi
null
Pathology
null
0050d8a4-a761-469b-b2cc-eb74efee146d
A child develops non blanching macules and papules on lower extremities, mild abdominal pain and skin biopsy showed IgA deposition. Most appropriate diagnosis is -
Drug induced vasculitis
HSP
Wegener's granuloniatosis
Kawasaki disease
1b
single
Henoch-Schonlein purpura (HSP), also known as IgA vasculitis, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. In the skin, the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain and abdominal pain. With...
Dental
Autoimmune skin disorders
fbabcda6-88f3-4f70-90b3-84f966b8e17c
Not true about iodophores ?
Inorganic compounds
Release iodine
Surfactants
Disifectant
0a
multi
Ans. is 'a' i.e., Inorganic compounds Iodine Iodine is more sporicidal than chlorine. Iodine is often used in aqueous and alcoholic solution as skin disinfectant. Aqueous and alcohol based povidone iodine preparations (Betadine) are best and safe skin disinfectants (antiseptics). Iodophores are organic compounds that s...
Social & Preventive Medicine
null
8d3fbb93-7987-4e7a-bdee-1ef5fbb1124b
Giant cells seen in Measles are called?
Hp bodies
Inclusion containing polykaryon
Koplik cells
Wahin-Finkeldey cells
3d
multi
Lymphoid organs typically have marked follicular hyperplasia, large germinal centers and randomly distributed multinucleated giant cells called Wahin-Finkeldey cells, which have eosinophilic nuclear and cytoplasmic inclusion bodies.Found in the paracoical region of hyperplastic lymph nodes in some patients of measles a...
Pathology
null
ab1932af-ff2f-458a-8b15-dd3bb48be8e7
The term anisometropia indicates
Refractive error
Long vision
Sho vision
Ageing process
0a
single
Ans. Refractive error
Ophthalmology
null
69a32c84-1fbd-43c1-a7ba-78ab7c542a11
A 40-year-old man presents to casualty with history of regular and heavy use of alcohol for 10 years and morning drinking for one year. The last alcohol intake was three days back. There is no history of head injury or seizures. On examination, there is no icterus, sign of hepatic encephalopathy or focal neurological s...
Diazepam
Haloperidol
Imipramine
Naltrexone
0a
multi
Ans. A i.e. Diazepam
Psychiatry
null
1b9ba6cb-4b24-4864-983f-132f6078274d
The features of uterine contraction in spastic lower segment are all except
Presence of fundal dominance
There may be reversed polarity
Inadequate relaxation in between contractions
Basal tonus is usually raised above the critical level of 20 mm Hg
0a
multi
Fundal dominance ,which indicates that the intensity is strongest ath the fundus,(not at the lower segment) with a gradual decrease downwards. Refer page no 109 of Text book of obstetrics ,sheila balakrishnan,2 nd edition.
Gynaecology & Obstetrics
Abnormal labor
ccbc242a-370c-45db-86c6-6ffe25cbeee3
10 year old child with posterior fossa mass. On biopsy following features were seen. What are these dense eosinophilic fibers marked with arrow?
Rosenthal fibers
The Alzheimer type II astrocyte
Corpora amylacea
None
0a
multi
Ans. (a) Rosenthal fibers*Rosenthal fibers are eosinophilic, corkscrew fibers found in pilocytic astrocytoma, the most common primary brain tumor in children. They contain two heat-shock proteins (aB-crystallin and hsp27) as well as ubiquitin.*They are seen in Alexander disease and, pilocytic astrocytoma.
Pathology
Central Nervous System
cc3b0128-9207-43ca-97bb-4b414a579a4e
A large baby is born with which complication in pregnancy
Gestational diabetes
Gestational hypeension
Cardiac disease
Anaemia
0a
single
Ans. is a i.e. Gestational diabetes
Gynaecology & Obstetrics
null
abf304fc-1d14-47cc-bace-facd6622a965
A woman was involved in an accident in which her left leg was crushed and immediate amputation had to be done but you couldn't get a prior consent as the victim was unconscious and the relatives were not available. Later her husband sues you you for doing an amputation without a valid consent. Which of the following se...
Section 92 IPC
Section 52 IPC
Section 88 IPC
Section 90 IPC
0a
single
Any harm caused to a person in good faith, even without consent is not an offence if the circumstances are such that it is impossible for the person to signify consent and has no guardian from whom it is possible to obtain a consent in time for the thing to be done in benefit as per section 92 IPC. Also know: As per se...
Forensic Medicine
null
81fe9a94-47ed-413f-9a6a-ddc676c95fdc
The Rorschach Inkblot test consists of a set of .......... standardized inkblots. These vary in colour, shading, form, and complexity.
5
7
9
10
3d
single
Rorschach Inkblot test- Evaluation of Personality, it contains 10 cards having ambiguous inkblot patterns and the subject has to interpret what he is seeing in the card from preselected options Extra Edge Thematic Apperception Test- Test is built on the assumption that people's stories reveal impoant aspects of their n...
Psychiatry
Miscellaneous
6cf9c68b-6920-49e1-9617-0464ebc41bff
Following are acute porphyrias except
ACUTE INTERMITTENT PORPHYRIA
Variegate porphyria
Heriditary corpoporphyria
Porphyria cutanea tarda
3d
multi
The acute porphyrias are acute intermittent porphyria (AIP), variegate porphyria (VP), aminolevulinic acid dehydratase deficiency porphyria(ALAD) and hereditary coproporphyria (HCP). The non-acute porphyrias are X-linked dominant protoporphyria (XLDPP), congenital erythropoietic porphyria (CEP), porphyria cutanea tarda...
Medicine
Genetics
17e554cf-7198-4d1e-9af7-27b871e1e49d
Which of the following glycolytic enzymes is used in gluconeogenesis?
Glucokinase
Aldolase
Pyruvate kinase
Phosphofructokinase
1b
single
Aldolase is the enzyme which catalyses reversible reaction of glycolysis. So this enzyme is utilised in gluconeogenesis. Glucokinase, pyruvate kinase and phosphofructokinase are enzymes which catalyse the reversible reaction of glycolysis.
Biochemistry
null
fb8542e4-9450-477c-b516-27143d0ad578
An organism with sterols in their cell wall is
Mycoplasma
Bacillus
Streptococcus
Spirillum
0a
multi
“Mycoplasma lacks a rigid cell wall and they are bounded by a triple-layered unit membrane that contains sterols. ” Mycoplasma PPLO - by Nocard & Roux • Smallest free-living organism • Gram-negative.highly pleomorphic organism, stained by Giemsa • Found in the form of elementary bodies & filaments of various size • Fac...
Microbiology
null
60841234-fd08-40a3-a44e-95a16ab29bab
Gas' in the tissue should be differenciated with -
Pseudomyxoma peritonei
Pseudomonas infection
Clostridium nouyi
Non clostridial infection
2c
single
null
Surgery
null
901a16f5-37e9-4567-8e7c-e722b1655b62
Chest X-ray of an industrial worker exposed to asbestos for 20 yrs shows diffuse appearance of lower lobe with 'comet tail' infarct on PA view. The most likely diagnosis is:
Mesothelioma
Lobular collapse
Bronchogenic carcinoma
Round atelectasis
0a
single
This is a case of mesothelioma secondary to asbestos exposure. The diffuse appearance of lower lobe with 'comet tail' infarct is typical of mesothelioma. Ref: Aicle: The Comet Tail Sign1; 1999
Radiology
null
c6560a39-e305-4557-a9d1-291239b7d197
Most common presentation of Renal cell carcinoma is
Abdominal mass
Hematuria
Flank pain
Nocturia
1b
single
null
Medicine
null
97ab74ed-0abb-4268-9641-649cc4776c70
In starvation, earliest to become depleted -
Carbohydrates
Proteins
Fats
None
0a
multi
Ans. is 'a' i.e., CarbohydratesMetabolic alteration during fasting-starvationo he metabolic changes observed in fasting are generally opposite to those described for absorptive (fed) state. In the absence of food, plasma levels of glucose, amino acids, and TGs fall, triggering a decline in insulin secretion and an incr...
Physiology
Pancreas
f1c7fa40-82f8-4a6c-8a8e-b00c1c5eb2f0
Endocrinologic factors associated with recurrent aboion include all of the following except-
Thyroid disease
Hyperprolactinemia
Luteal phase insufficiency
Reduced secretion of luteinizing hormone (LH)
3d
multi
Endocrinologic factors associated with recurrent aboion include - Luteal phase insufficiency Diabetes mellitus Hypersecretion of luteinizing hormone (LH) Thyroid disease Insulin resistance Polycystic ovarian syndrome, Hyperprolactinemia Decreased ovarian reserve.
Gynaecology & Obstetrics
Aboions, Spontaneous & Induced Emergency Contraception (Hey,whats the hurry !)
ac9978e4-fe06-4656-82e9-14d693aeab6f
Primitive streak remanants give rise to ?
Neuroblastomas
Wilm's tumour
Sacrococcygeal teratoma
Hepatoblastoma
2c
single
Sacrococcygeal teratoma (SCT) is a type of tumor known as a teratoma that develops at the base of the coccyx (tailbone) and is thought to be derived from the primitive streak. Sacrococcygeal teratomas are benign 75% of the time, malignant 12% of the time, and the remainder are considered "immature teratomas" that share...
Surgery
Urology
1f5ebaf0-ca14-4175-9319-e2ffb82cc9f5
Which is safest to be used in asthmatic patients:
Nitrazepam
Phenobarbitone
Chloral hydrate
All hypnotics are safe
2c
multi
C i.e. Chloral hydrate
Anaesthesia
null
fbcd3309-51db-4fac-9419-a2c87550d542
True statements about the twin-to-twin transfusion syndrome include which of the following?
The donor twin develops hydramnios more often than does the recipient twin
Gross differences may be observed between donor and recipient placentas
The donor twin usually suffers from a hemolytic anemia
The donor twin is more likely to develop widespread thromboses
1b
multi
In the twin-to-twin transfusion syndrome, the donor twin is always anemic, owing not to a hemolytic process but to the direct transfer of blood to the recipient twin, who becomes polycythemic. The recipient may suffer thromboses secondary to hyper-transfusion and subsequent hemoconcentration. Although the donor placent...
Gynaecology & Obstetrics
Obstructed Labour