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135
e0c2cf58-aa5c-4516-b250-79b76d99a2cc
Drug of choice for OCD is?
Clomipramine
Fluoxetine
Carbamezapine
Chlorpromazine
1b
single
ANSWER: (B) FluoxetineREF: Kaplan 9th ed p - 622OCDTreatment of choice: behaviour therapyDrug of choice: SSRI2nd drug of choice: comipramine
Psychiatry
Neurotic Disorders
7a895da1-0450-40b7-a201-1a6db801461f
PAS positive are all the following except -
Glycogen
Lipids
Fungal cell wall
Basement membrane of bacteria
3d
multi
Ans-DThe basement membrane of bacteria
Unknown
null
9b6f8e62-54e1-4b6d-9ec7-1acd174bdd71
Increased serum amylase in pleural effusion is seen in
Rheumatoid arthritis
Tuberculosis
Malignancy
Pulmonary embolism
2c
single
(Malignancy) (269- CMDT-08) (1658-H17th)Serum amylase level in PE - suggest pancreatits, pancreatic pseudocyst, adenocarcinoma of the lung or pancreas or esophageal rupture, - MalignancyGlucose < 60 mg/ dL - occurs in Malignancy, Bacterial infections, Rheumatoid pleuriticIncreased amvlase acids are found in perforated ...
Medicine
Respiratory
b6cd0c9f-13ee-4b1f-8f40-6d7f1252d99e
Diffuse specific lesions on intestinal biopsy are seen in -a) Celiac sprueb) Whipples diseasec) Agammaglobulinemia d) Abetalipoproteinemal
abc
bcd
ac
bd
1b
single
null
Medicine
null
bdf06820-2bf1-4f27-b49d-64a09e85366a
Pyrogens act on which site of brain ?
Basal ganglia
Limbic system
Thalamus
Hypothalamus
3d
single
Ans. is 'd' i.e., Hypothalamus PyrogenesPyrogenes are substances that cause fever.Pyrogens may be exogenous or endogenousExogenous - Bacterial toxinsEndogenous - IL-1, TNF-a, IL-6, Interferons, Ciliory's neurotropic factorThese pyrogenes increase the level of PGE, in the hypothalamus that elevates the thermoregulatory ...
Physiology
null
647da693-d046-4b8a-a0ad-89abff2cbee2
Hypertrophy means -
Increased protein content of the cells
Increase in size of cells
Increase in number of cells
None of the above
1b
multi
Ans. is 'b' i.e., Increase in size of cells Hypertrophy o Hypertrophy refers to an increase in the size of cells without increase in the number, resulting in an increase in the size of tissue. Hypertrophy involves cell enlargement without cell division. So, hypertrophied organ has just larger cells, but no new cells Hy...
Pathology
Cellular Responses and Adaptations to Stress
aaa09f14-d097-401e-a543-a9a9e4fa9a7d
A patient was diagnosed with schizophrenia and was staed on haloperidol 5mg. On 3rd day he presented with uprolling of eyes. A complete neurological examination revealed no spasticity or any other abnormalities except uprolling of eyeballs. Visual acuity was found to be normal. What is your likely diagnosis?
Seizure
Acute dystonia
Malingering
Akathesia
1b
multi
* <48 hours of staing antipsychotics * M.C in======Younger black males * If a patient develops dystonia he is more prone for eps Patient considers this as an Allergic reaction , thereby may stop drugs Layryngeal dystonia is a Psychiatric emergency, should be treated with IV lorazepam TREATMENT * Diphenhydramine * Benzt...
Psychiatry
Pharmacotherapy in psychiatry
02979b58-aa6b-426a-814c-f377d7ac99ab
Risk factor prevention at which level
Primordial
Primary
Secondary
Tertiary
0a
single
(A) (Primordial) (39 - Park 22nd)PRIMORDIAL PREVENTION* Special attension is the prevention of chronic disease* Prevention of the emergence or development of risk factors in countries or population groups in which they have not yet appeared* For example, many adult health problems (eg obesity hypertension) have their e...
Social & Preventive Medicine
Concept of Health and Disease
40b70c47-183a-4a11-b538-f5455a12f8c1
Venous drainage of upper pa of uterus and placenta is through :
Ovarian vein
Uterine vein
Internal iliac vein
None
0a
multi
Ovarian vein
Gynaecology & Obstetrics
null
b562b1ef-4224-4995-a146-28efae045d88
As compared to permanent tooth, root formation in primary tooth:
Take less time
Take more time
Same time
Is complete when tooth erupts in oral cavity
0a
single
null
Dental
null
9db30337-67b8-48ca-a713-8a6ffe0b5af1
Which of the following is true about venous thrombosis?
It affects only the deep venous system
Most impoant factor for development of deep venous thrombosis is hospital admission
Coralline thrombus is platelet aggregate surrounded by white blood cells
Lung infarction is a common complication of deep venous thrombosis
1b
multi
Answer- B. Most impoant factor for development of deep venous thrombosis is hospital admissionVenous thrombosis is the formation of a semi-solid coagulum within the venous system and may occur in the superficial system.Patients are at risk of dweloping a post-thrombotic limb and venous ulceration Virchow triad-Changes ...
Surgery
null
58a070e3-b4d0-458e-bf72-97ba8f1eea5e
Gateway of tears is:
Rathke pouch
Sinus of morgagni
Killians dehiscence
Pharyngeal bursa
2c
single
Killians dehiscence is also called 'gateway of tears'
ENT
null
2da0387f-a1c4-43c1-8096-fe225e278ec6
A 27 year old sexually active male develops a vesiculobullous lesion on the glans soon after within 8hrs taking tablet diclofenac for viral fever. The lesion healed with hyperpigmentation.The most likely dignosis is-
Behcet's syndrome
herpes genitalis
fixed drug erruption
pemphigus vulgaris
2c
multi
Fixed drug eruption It characteristically recur at the same site following administration of offending drugs or occasionally a member of the same group of drugs. They occur 30min to 8hrs after drug administration Most common drugs: Sulfonamides NSAIDS Dapsone Batbiturates Ciprofloxacin Phenytoin Griseofulvin Metronidaz...
Dental
Autoimmune skin disorders
972c5769-f186-4a55-a10a-e56c9866c7dc
Isotope (s) used in high dose rate brachytherapy – a) lr192b) Co–60c) Cs–l33d) Ra 226 e) Pd103
ac
a
ab
bc
2c
single
"Although cobalt - 60 and cesium - 137 have been used in the past, iridium - 192 is the most commonly used radioisotope in HDR brachytherapy".                                                                       — The physics of radiation therapy Note - Cs-137 is used in HDR brachytherapy, while option c i.e. Cs - 133...
Radiology
null
324bcd12-a946-43cc-8081-ddd693151c9c
A patient presents with erythematous scaly lesions on extensor aspect of elbows and knee. The clinical diagnosis is got by :
Auspitz sign
KOH smear
Tzanck smear
Skin biopsy
0a
single
Ans. is 'a' ie Auspitz signErythematous scaly lesions on extensor aspect of elbow and knee favours the diagnosis of Psoriasis.The clinical diagnosis of psoriasis can be made by demonstrating Auspitz sign.It is a characteristic finding of psoriasis in which removal of scale leads to pinpoint bleeding.Tzanck testis used ...
Skin
Psoriasis
aa8cbb1e-a090-42b7-af4b-f674b719efe8
27-year-old white man presents to his family doctor complaining of being tired all the time and having a slight fever for the past two weeks. He recently returned from a trip to Las Vegas, where he indulged in some of the infamous nightlife. His physical exam is unremarkable except for a macular rash over his trunk and...
Chlamydia trachomatis
Neisseria gonorrhea
Treponema pallidum
Borrelia burgdorferi
2c
multi
Treponema pallidum Transmitted through unprotected sexual activity with an infected individual. Presents with the symptoms of secondary syphilis, which includes malaise, mild fever, and rash on the palms and trunk. The primary lesion (chancre) may go unnoticed because it is painless and subsides in a few weeks.
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
80771152-c449-45c4-a556-0345e358dccc
Which of the following is having a 90% associated with HLA B27
Ankylosing spondylitis
Rheumatoid ahritis
Psoriasis
Reiter's syndrome
0a
single
Ref Robbins 9/e p205 A positive result meansHLA-B27 was found in your blood. You may have a higher-than-average risk of ceain autoimmune diseases, such as ankylosing spondylitis and reactive ahritis.
Anatomy
General anatomy
5f56f86a-2f02-4acb-a1dd-7a5eaf4385dc
Growth of oral structures is mainly influenced by factors:
Hereditary
Environmental
Hereditary-influenced by environmental factor
None of the above
2c
multi
Van Limborgh after review of the sutural theory, cartilaginous theory and functional matrix theory has summarized the following features: 1. Intrinsic genetic factor controls chondrocranial growth. 2. Epigenetic factors originating from skull cartilages and head tissues control desmocranial growth. 3. Local environment...
Dental
null
c7192eea-2a32-460a-a071-13bc5c005fe4
Foramen of Morgagni refers to an opening in?
The brain
The lesser omentum
The skull
The diaphragm
3d
single
The sinus of Morgagni or ventricle of the larynx is a narrow fusiform cleft between the vestibular and vocal folds. the anterior pa of the sinus is prolonged upwards as diveiculum between the vestibular fold and the lamina of the thyroid cailage .this extension is known as the saccule of the larynx. The saccule contain...
Anatomy
Head and neck
840f27e2-82d1-414c-92db-eff63a396c74
A 10-year-old boy presents with increase bilirubin, increased bilirubin in urine and no urobilinogen Diagnosis is:
Gilbert syndrome
Hemolytic jaundice
Viral hepatitis
Obstructive jaundice
3d
single
Ans. D. Obstructive jaundiceLaboratory tests in three different types of JaundiceConditionSerum BilirubinUrine UrobilinogenUrine BilirubinNormalDirect: 0.1-0.4mg/dL Indirect: 0.2-0.7mg/dL0-4mg/24hAbsentHemolytic anemiaIndirectIncreasedAbsentHepatitisDirect and indirectDecreased if micro-obstruction is presentPresent if...
Biochemistry
Vitamins and Minerals
20e03796-d08a-472e-8c58-303fdf196dae
Negative nitrogen balance is the characteristic feature of which phase of convalescence after surgery?
Catabolic phase
Anabolic phase
Fat gain phase
Tuning point phase
0a
single
null
Biochemistry
null
c29591fc-1ee7-4be3-b878-dd82dffc9b99
All are true regarding fetal BBC's except –
Elevated 2,3 DPG
Decreased carbonic anhydrase activity
Decreased life span
High RBC volume
0a
multi
Fetal RBC contains less 2, 3 DPG.
Pediatrics
null
c26ff4e0-825a-4916-9b06-405ba81be1fa
NREM sleep is associated with:-
Basal forebrain area
Dorsal raphe nucleus
Medulla
All of the above
3d
multi
NREM sleep generation is associated with 5 anatomical sites: * Basal forebrain area Thalamus Hypothalamus Dorsal raphe nucleus Nucleus tractus solitaries of the medulla Preoptic lesions produce hyposomnia, whereas electrical and thermal stimulation of this area produces sleep changes. Thalamus (especially reticular for...
Psychiatry
Sleep Disorders
f7456bfd-fc46-4c00-b326-2c4cd6bfea77
Which of the following is the most specific test for Rheumatoid ahritis
Anti-ccp antibody
Anti Igm antibody
Anti IgA antibody
Anti IgG antibody
0a
single
to establish diagnosis of rheumatoid ahritis are * Clinical criteria * ESR and CRP * Ultrasound or MRI * Rheumatoid factor and anti-citrullinated peptide antibodies DAVIDSON&;S 22nd EDITION;PAGE NO 1100
Medicine
Immune system
92f241b1-5dd7-4309-be7d-575987eb3c07
A young male presents with ear discharge since three years; recently developed swelling in the neck below and behind the angle of mandible, toicollis; on the examination, the external auditory canal was filled with granulation tissue. What is the diagnosis?
Luc's abscess
Citelli's abscess
Bezold's abscess
Parapharyngeal abscess
2c
single
Bezold's abscess It can occur following acute coalescent mastoiditis when pus breaks through the thin medial side of the tip of the mastoid and presents as a swelling in the upper pa of the neck. The abscess may Lie deep to sternocleidomastoid, pushing the muscle outwards. Follow the posterior belly of digastric and pr...
ENT
Ear
ec560c3b-7ce3-46f5-9020-9263cb87db0f
Not a pa of kangaroo mother care -
Skin to skin contact
Early discharge
Free nutritional supplements
Exclusive breast feeding
2c
single
The 4 components of kangaroo mother care are all essential for ensuring the best care option especially for low bih weight babies. This include: Skin to skin contact on mothers chest Adequate nutrition through breast feeding Ambulatory care as a result of earlier discharge Suppo for mother and family in caring baby. Pa...
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
a3ebfb78-6640-488c-a174-1a8aeb345690
A 6-year-old child has an accident and had elbow, after 4 years presented with tingling and numbness in the ulnar side of finger, fracture is
supra condylar humerus
lateral condylar humerus
olecranon
dislocation of elbow
1b
single
Ans. is 'b' i.e.lateral condyle humerus This child had lateral condyle of humerus 4 yrs back. He is now presenting with symptoms of tardy ulnar palsy. Lateral condyle of humerus may lead to cubitus valgus deformity because of diminished growth at the lateral side of distal humeral epiphyses. Cubitus valgus deformity le...
Orthopaedics
Supracondylar Fracture
0270af35-eb8b-4c23-b7fb-31e989140960
All of the following can be used to treat alcohol dependence except
Naltrexone
Acamprosate
Flumazenil
Disulfiram
2c
multi
Naltrexone is orally effective opiod antagonist useful in alcohol withdrawal. Acamprosate an NMDA receptor antagonist is useful in preventing relapse. Disulfiram is used to make alcohol consumption an unpleasant experience. It inhibit the enzyme aldehyde dehydrogenase. Ref: KD Tripathi 8th ed.
Pharmacology
Central Nervous system
805f167d-13ad-4949-9267-1ebce3a48a9f
A 26 years old G2P1L1 at 10 weeks complains of pain abdomen and bleeding per vaginum. On examination products of conception are seen paially extruding through the cervix. What is your diagnosis?
Inevitable aboion
Threatened aboion
Complete aboion
Incomplete aboion
3d
multi
Bleeding follows paial or complete placental separation and dilation of the cervical os in incomplete aboion. The fetus and the placenta may remain entirely within the uterus or paially extrude through the dilated os.Management is Evacuation or medical termination (if stable).Reference: William's Obstetrics; 25th editi...
Gynaecology & Obstetrics
General obstetrics
131a180a-602e-417e-86c0-38e8b6f3a50a
Initial ECG change in Hyperkalemia is?
Tall tented T waves
PR prolongation
qRS widening
ST segment depression
0a
multi
Ans.(a) Tall tented T wavesRef: Harrison 19th ed. / 310Serum potassium > 5.5 mEq/L is associated with repolarization abnormalities:* Peaked T waves (usually the earliest sign of hyperkalemia) Serum potassium >6.5 mEq/L is associated with progressive paralysis of the atria:* P wave widens and flattens* PR segment length...
Medicine
Electrocardiography
caf01230-6feb-4cd6-b44b-1bfc9fea1b9e
ANCA positive vasculitis include all of the following Except:
Wegner's granulomatosis
Churg strauss syndrome
Microscopic PAN
Good pasture's syndrome
3d
multi
Answer is D (Good pasture's syndrome): Goodpasture's syndrome is not classified as an ANCA positive vasculitis.
Medicine
null
532a83fe-5b91-4f6f-ae20-e6e690696a8a
The type of estrogen found in highest concen- tration in adult female is-
Estrone
Estriol
Estradiol
None
2c
multi
Ans. is 'c' i.e.. Estradiol f Ref: Principles of medical physiology p. 216]o Estradial, estrone and estrial, all three are found in blood, but estradiol is the most potent estrogen.o Major estrogen in normal adult women - Estradiolo Major estrogen in postmenoapusal women - Estroneo Major estrogen in pregnant women - Es...
Physiology
Sex Hormones
a9a5febc-b0bf-45a6-bedc-f540276ca002
Apical transportation is also known as
Curing
Zipping
Ledging
Apical perforation
1b
single
null
Dental
null
c6d962ab-9dbb-4c07-9e13-6020d3c59b72
Pro - inflammatory cytokine is?
IL-1
IL-3
IL-6
IL-10
0a
single
Ans. is 'a' i.e., IL-1 Proinflammatory cytokinesi) Major:- IL-1, TNF- a, IL-6ii) Other:- IL-2, IL-4, IL-5, IL-6, IL-8, IL-11, IL-12, IL-15, IL-21, IL-23, IFN- g, GM-CSFAnti-inflammatory cytokines* IL-4, IL-10, IL-13, and transforming growth factor-b (TGF-b).
Pathology
Inflammation & Repair
a8af28cb-9dae-4584-a3b8-2d3f635f532c
Direct standardization is used to compare the moality rates between two countries. This is done because of the difference in -
Cause of death
Numerators
Age distributions
Denominators
2c
single
ref: Park&;s 23rd edition pg 58 A standard population is defined as the one for which the numbers in each age and sex group are known.
Social & Preventive Medicine
Epidemiology
d90c3714-243a-40af-b497-1dbec4fd341f
Which is the most common cause of thrombocytopenia in an ICU patient?
Sepsis
Bone marrow failure
ITP
Drug induced
0a
single
Ans. is 'a' i.e., Sepsis Thrombocytopenias in ICU patients :* Thrombocytopenia is a common laboratory abnormality that has been associated with adverse outcomes in ICU patients.* Thrombocytopenia is defined as platelet count < 150 X 103 cells / mcL.* Following table depicts the probable mechanisms and the causes for pr...
Medicine
Blood
02f60eb9-0c8b-4bb9-9de4-bbdef04292a8
Which is not primary amenorrhea?
Sheehan's syndrome
Kallmann's syndrome
Mayer Rokitansky Koster Hauser syndrome
Turner syndrome
0a
multi
Ans. is a, i.e. Sheehan's syndromeRef: Shaw 14th/ed, p256-257* Kallmann's sydnrome is due to hypothalamic dysfunction characterized by a deficiency of gonadotropin releasing hormone (GnRH) causing a hypogonadotrophic hypogonadism. This is associated with anosmia. It can occasionally be associated with optic problems, s...
Gynaecology & Obstetrics
Disorders in Menstruation
445ec67f-406e-489e-bd05-783378ba94e4
A female undergone surgery for left breast cancer 3 yrs back now developed blue nodule on same side
Lymphangiosarcoma
Recurrence
Hemangioma
Cellulitis
0a
single
Answer- A. LymphangiosarcomaAngiosarcoma is a vascular tumor which may arise de novo in the breast or as a complication of the radiation therapy.
Surgery
null
048cbd81-a263-4a46-ad8f-19b37a33fa48
An expansion alliance made with an expansion screw is an example of:
Simple anchorage
Reciprocal anchorage
Multiple anchorage
Reinforced anchorage
1b
multi
null
Dental
null
a1cd9953-168a-41fa-a948-9f6ef8dd9aca
Day care anesthesia is best achieved with
Enflurane
Isoflurane
Propofol
Methoxyflurane
2c
single
Propofol
Anaesthesia
null
4a7e4a82-c921-46b8-b8e5-9d903fc7b76e
Not true about post-transcriptional modification of RNA-
5' Capping
Addition of poly A tail
Removal of introns
Glycosylation
3d
multi
Ans. is 'd' i.e., Glycosyiution.m-RNA processingo Prokaryotic mRNA is functional immediately upon synthesis, i.e. prokaryotic primary transcript of mRNA is functional. Thus it does not require post-transcriptional modification. In Eukaryotes the primary transcript of mRNA is the hn RNA (hetrogeneous nuclear RNA). After...
Biochemistry
Transcription
bdcbae06-7aab-4225-97e7-a7d1162bb400
Rigor mois not seen in: AIIMS 13
Fetus < 7 months of age
Full term fetus
Elderly
Anemic person
0a
single
Ans. Fetus < 7 months of age
Forensic Medicine
null
418a3875-0237-4742-82eb-70337557f49a
Most commonly used tuning fork in ear examination is
128 Hz
256 Hz
512 Hz
1024 Hz
2c
single
512Hz is used normally Note: These tests are performed with tuning forks of different frequencies such as 128, 256, 512, 1024, 2048 and 4096 Hz, But for routine clinical practice, tuning fork of 512 Hz is ideal. Forks of lower frequencies produce a sense of bone vibration while those of higher frequencies have a shoer ...
ENT
Ear
5abd5e16-15ad-40eb-9011-b51703c08d37
Subtrochanteric fractures of the femur can be treated by all of the following methods except
Skeletal traction on Thomas' splint
Smith Petersen Nail
Condylar blade plate
Ender's nail
1b
multi
Smith Peterson Nail is a cannulated tri-flanged nail that was used for internal fixation of fracture neck of femur Results obtained by S-P nail were dissatisfactory and it is no more recommended for use these days. Other three options are used for the treatment of the subtrochanteric fracture.
Orthopaedics
null
d3d67009-2921-4da2-9482-bd1a5cc49538
All of the following side effects are produced by Cisplatin except
Ototoxicity
Nephrotoxicity
Coasting effect
Pulmonary fibrosis
3d
multi
Cisplatin can cause ototoxicity, nephrotoxicity, coasting effect (peripheral neuropathy) and severe nausea and vomiting. Pulmonary fibrosis is seen with Bleomycin and Busulfan.
Pharmacology
null
da68c86d-0381-434c-85d0-fe1356f9b946
True about measles is/are a) Incubation period (I.P.) is 10-12 days b) Confunctivitis common c) Rash starts on abdomen d) Koplik spots are seen on fundus examination
ab
bc
cd
bd
0a
multi
null
Medicine
null
3a47f062-8be2-4f63-94d9-bc7cbf944290
Depressor reflex, Bezold-Jarisch reflex, produced by the following stimulus:
Atrial overload
Myocardial infarction
Ventricular distension
Isotonic exercise
2c
single
Ventricular distension can produce a powerful depressor reflex called the Bezold-Jarisch reflex; vagal afferents of this cardiopulmonary reflex are also activated by chemical stimulation (eg, prostanoids, cytokines, serotonin, and classically, Veratrum alkaloids). The central connections for this reflex are in the nucl...
Physiology
null
4133a483-ab83-4a33-a86c-6c5e00b1f709
Shape of birbeck granules is -
Tennis racket
Hockey stick
Bat
Ball
0a
multi
Ans. is 'a' i.e., Tennis racket o Under the electron microscope, Birbeck granules have a pentalaminar, rodlike, tubular appearance and some- times a dilated terminal end resembling tennis-racket appearance.
Pathology
Blood
6da33607-b0fe-4ce0-88a0-275d35bf1ee0
Extremely low birth weight -
<1000
<1500
<2500
<2800
0a
single
Ans. (a) <1000 gmRef : OP Ghai 8th ed./125* Normal birth weight - 2800 gm- 3000gm* Low birth weight(LBW) - < 2500 gm* Very low birth weight(VLBW) - < 1500 gm* Extremely low birth weight (ELBW) - < 1000 gm.
Pediatrics
Newborn Infant - Physical Examination
0e97cd05-876b-4a27-9710-0ae41c0b0ec0
Memory T cells can be identified by using the following
CD 45RA
CD45RB
CD45RC
CD45RO
3d
single
Ref Harrison 17/e p2021 CD45 (lymphocyte common antigen) is a receptor-linked protein tyrosine phosphatase that is expressed on all leucocytes, and which plays a crucial role in the function of these cells. ... These CD45-associated molecules may play an impoant role in regulatingCD45 tyrosine phosphatase activity and ...
Anatomy
General anatomy
d3fcd822-1bc8-4fb3-b8b7-85937a9628d2
Which of the following fuel gases used for soldering, has the highest heat content
Hydrogen
Natural gas
Acetylene
Propane
3d
single
null
Dental
null
12098247-4d8f-4980-99d1-325014f72bcd
Which is true of typhoid -
Female carriers are less common
Male carriers though less are more dangerous
Gall bladder usually not involved in carrier state
Tetracycline is the DOC for carriers
1b
multi
null
Social & Preventive Medicine
null
09a2273c-f6e5-4124-a1f0-c17d6a8d3144
All of the following are globular proteins except:
Prolamines
Albumin
Globulin
Myosin
3d
multi
null
Biochemistry
null
9ec100e0-c6b0-4164-b3c6-a2685e2a4cd3
A 4-month-old infant has undergone surgical treatment for meningomyeloencephalocele. At bih, an operation was carried out in the posterior cranial fossa to paially replace brain cerebellar contents to an intracranial position. In investigations for progressive hydrocephalus, it is noted that there is herniation of the ...
Fusion of the frontal lobes
Fusion of the temporal, parietal, and occipital lobes
Abnormal elongation of the medulla and lower cranial nerves
Paial or complete absence of the pituitary gland
2c
multi
Abnormal elongation of the medulla and lower cranial nerves may be evident in Arnold-Chiari syndrome. Additional features include fusion of the corpora quadrigemina, leading to a "beaked" tectum; paial or complete absence of the corpus callosum; and microgyria.
Surgery
Cerebrovascular Diseases
932f40b0-3df1-445c-8932-36262e63e157
A patient of RHD developed infective endocarditis after dental extraction. Most likely organism causing this is -
Streptococcus viridans
Streptococcus pneumoniae
Streptococcus pyogenes
Staphylococcus aureus
0a
single
Viridans streptococci Commensals in the mouth and upper respiratory tract. Cause transient bacteremia following tooth extraction or other dental procedures; -MC cause of subacute endocarditis: Streptococcus Viridans - MC Streptococcal species in Viridans group causing endocarditis: S. sanguis mc cause of Native valve e...
Microbiology
Systemic Bacteriology Pa 1 (Gram Positive Cocci, Gram Negative Cocci)
91f27218-d7f2-4e06-a676-7e320bf5ebe8
Disease highly transmitted during incubation period is -
Peussis
Cholera
Measles
Brucellosis
0a
single
Whooping cough is most infectious during the catarrhal stage. The infective period may be considered to extend from a weak after exposure to about 3 weeks after the onset of the paroxysmal stage although communicability diminishes rapidly after the catarrhal stage. (refer pgno:163 park 23 rd edition)
Social & Preventive Medicine
Epidemiology
7b7dbc9c-5bf8-40d0-8c01-9647180f289b
Uveitis is associated most commonly with :
Rheumatoid arthritis
Systemic JRA
Pauciarticular JRA
Poly articular JRA
2c
single
Ans. is 'c' ie Pauciarticular JRA Uveitis can be seen in both pauciarticular and polyarticular JRA but is much more commonly associated with pauciarticular JRA.It is seen in about 20-25% of cases of pauciarticular and only 5% of polyarticular JRA.
Ophthalmology
Uveal Tract
0f605372-c677-410f-8ada-0abf9019e865
A 10-mm calculus in the right lower ureter associated with proximal hydroureterone-phrosis is best treated with
ESWL
PCNL
Open ureterolithotomy
Ureteroscopic retrieval
3d
single
null
Surgery
null
dd875203-5ebe-409b-8bb2-7924f5f881bf
All of the following are seen in deep vein thrombosis except
Pain
Discolouration
Swelling
Claudication
3d
multi
Claudication occurs in arterial occlusion
Surgery
null
2c5d5a57-0ded-47a6-8987-a10488ea427f
Integrated management of childhood illness (IMCI) intiative was taken to prevent morbidity and moality from all of the following except -
Malaria
Malnutrition
Otitis Media
Neonatal tetanus
3d
multi
Ans. is `d' i.e., Neonatal tetanus Integrated management of childhood iliness.tIMCD The extent of childhood morbidity and moality caused by following diseases is substantial. i) Diarrhea iii) Malaria v) Malnutrition ii) ARI (pneumonia, otitis media) iv) Measles o Most sick children present with signs and symptoms of mo...
Social & Preventive Medicine
null
d8e7f6bb-791f-4235-b1fe-3a5aae120d20
Hostile witness is covered under IPC section
191
192
193
194
0a
single
Sec 191 IPC states that whoever, being legally bound by an oath or by an express provision of law to state the truth, or being bound by law to make a declaration upon any subject, makes any statement which is false, and which he either knows or believes to be false or does not believe to be true, is said to give false ...
Forensic Medicine
Medico legal procedures
ebff54b9-c931-4287-9c78-35b2e07cdf86
All statements are true except remifentanil is true except
Useful for sho painful procedures
Metabolized by plasma esterases
Equipotent as fentanyl
Long acting anesthetic
3d
multi
Refer Goodman Gilman 11/e p 572 Remifentanil is shoest acting opioid due to its metabolism by plasma esterases Due to its sho duration of action, it is indicated for sho term painful procedures Intravenous bolus dosing is not practical Potency is equal to fentanyl
Pharmacology
Anesthesia
224d86e3-a1a1-44f2-8c45-66cdac69980a
EMLA constituent is –
Lidocaine + Cocaine
Lidocaine + Prilocaine
Lidocaine + Bupivacaine
Bupivacaine + Prilocaine
1b
single
Eutectic mixture of local anaesthetics (EMLA) is a mixture of 2.5% lidocaine and 2.5 prilocaine.
Anaesthesia
null
7b2b29f4-0bb8-4f42-8d49-73df68ebc337
Keratic precipitates are most commonly seen in -
Corneal ulcers
Uveitis
Nuclear cataracts
Keratoconus
1b
single
Ans. is 'b' i.e., Uveitis o Keratic precipitates (KPs) are proteinaceous cellular deposits occurring at the back of cornea (corneal endothelial deposits). Keratic precipitates are formed by the aggregation of polymorphonuclear cells, lymphocytes, and epitheloid cells. In the setting of uveitis, the bimicrosopic appeara...
Ophthalmology
Uveal Tract
34d3fb84-0234-40aa-ac97-7263a8cb1329
Regarding glutathione which of the following is/are true:
It helps in absorption of ceain amino acids
It inactivates some enzymes
It helps in membrane transpo
All
2c
multi
Ans:C.)It helps in membrane transpo. GLUTATHIONE: Glutathione is a tripeptide made up of glutamate, cysteine and glycine (T-glutamyl-cysteinyl-glycine). Glutathione is present in all mammalian cells except neurons. The sulphydryl (-SH) group of cysteine residue is the reactive poion of glutathione which can undergo oxi...
Biochemistry
null
67efd388-c8b7-49b8-b011-3f12f5a81805
Presenting symptom of nasal myiasis is
Severe irritation with sneezing
Maggots
Nasal pain
Impaired olfaction
0a
single
Clinical features of nasal myiasisInitial symptoms (3-4 days maggots):- Intense irritation, sneezing, headache, blood stained discharge, lacrimationLater:- Maggots may crawl out of the nose and there is a foul smellRef: PL Dhingra, Diseases of Ear, Nose & Throat, 7th edition, pg no. 181 - 182
ENT
Nose and paranasal sinuses
f499a21c-9b04-4146-b928-303c4198579a
Fouh ventricle develops from?
Telencephalon
Mesencephalon
Diencephalon
Rhombencephalon
3d
single
Lateral ventricle develops from the cavity of telencephalon. Third ventricle develops from diencephalon. Cavity of mesencephalon remains narrow and forms the aqueduct, while the cavity of rhombencephalon forms the fouh ventricle.
Anatomy
null
68b5caed-e01f-4385-aff7-44808d77250a
Diabetic neuropathy is a
Distal symmetric sensory polyneuropathy
Mononeuritis
Autonomic neuropathy
All of the above
3d
multi
Diabetic neuropathy causes substantial morbidity and increases moality. It is diagnosed on the basis of symptoms and signs, after the exclusion of other causes of neuropathy . Depending on the criteria used for diagnosis, it affects between 50% and 90% of patients with diabetes, and of these, 15-30% will have painful d...
Medicine
Endocrinology
720e1e5d-cacc-4bd0-8d66-a6c3d32a32fb
Chronotrophic means: March 2010
Drugs affecting the contractility of hea
Drugs affecting hea rate
Drugs affecting the myocardial blood flow
Drugs affecting diastolic relaxation
1b
single
Ans. B: Drugs affecting hea rate Chronotropic effects are those drugs that change the hea rate. Chronotropic drugs may change the hea rate by affecting the nerves controlling the hea, or by changing the rhythm produced by the sinoatrial node. Positive chronotropes increase hea rate; negative chronotropes decrease hea r...
Pharmacology
null
3d322929-64ee-40fa-a341-f6892fe631c0
In measuring Vickers hardness no. which of the following is used:
Spherical indenter
Steel ball indentation
Rhomboid shaped indenter
136-degree diamond pyramid
3d
multi
null
Dental
null
02d215cc-24a9-4c99-8971-e1fb81435c81
For pericardial calcifications, which is the best investigation-
MRI
Transesophageal echocardiography
USG
CT scan
3d
single
Calcification anywhere in the body - IOC is CT scan Except for gall stones - IOC is USG So, for pericardial calcifications, the best investigation is CT scan. Figure: An incidental discovery of focal calcific plaque within the visceral pericardium. The patient was asymptomatic.
Radiology
CT SCAN
cb6fb81a-ae0e-4946-8085-1447417de0d3
Most specific test for organophosphorous poisoning is:
RBC cholinesterase level
Plasma cholinestrase level
RBC uroporphyrin level
Measurment of serum level of organophosphorous
1b
single
B i.e. Plasma cholinesterase level
Forensic Medicine
null
685cd88a-d823-48ed-a78f-4d6b065ee25d
Lambda is meeting point of:
Coronal and sagittal suture
Coronal and lambdoid suture
Sagittal and lambdoid suture
None of the above
2c
multi
The lambda is the meeting point between the sagittal and lambdoid sutures. In the foetal skull, this is the site of the posterior fontanelle which closes at two to three months of age.
Anatomy
null
49fd22db-b917-4e72-9750-6c0fdb8643b7
CSF examination in a one day old term male infant with convulsions reveals cell count -- 10 RBCs/HPF, 50 cells; protein -- 70 mg/dl.; sugar -- 30 mg/dl/Blood sugar 40 mg/di The child is likely to be suffering from
Meningitis
Intracranial bleed
Hypoglycemia
None of the above
1b
multi
(B) Intracranial bleed # RBCs are normally not present in the CSF and their presence indicates traumatic tap or subarachnoid hemorrhage.# CSF characteristics:> Idiopathic seizures --Clear CSF with normal protein, normal glucose, no WBC's, no RBC's, normal opening pressure and normal % Gamma globulin.> Bacterial meningi...
Medicine
Miscellaneous
3f7da90b-7b58-4737-bf2a-03764640a865
Feature of osteoahritis is -
Heberden node
Increased ESR
Onycholysis
Z deformity
0a
single
Ans. is 'a' i.e., Heberden node Joint involvement in OA Common joints : Knee, Hip, Spine (cervical, lumbosacral), Hand (PIP, DIP, first carpometacarpal), first tarsometatarsal. Uncommon joint : Shoulder Spared : Wrist, elbow, ankle, metacarpophalangeal. In osteoahritis of hand : Distal interphalangeal joint :- Heberden...
Surgery
null
e0fe8e8a-62d2-49f2-a17b-ac856889a1b5
Most common cause of UTI in a neonate is
E.coli
S. aureus
Enterococcus
Anerobes
0a
single
Causative agents of UTI:Uncomplicated UTIComplicated UTI*E.coli *Klebsiella*Proteus species*Enterobacter*Staphylococcus saprophyticus*Enterococci *Chlamydia , Neisseria *Ureaplasma, Mycoplasma . Adenovirus *E.coli *Klebsiella*Proteus species*Serratia marcescens*Pseudomonas *Enterococci Staphylococci Ref:Harrison's infe...
Microbiology
Bacteriology
caccb5da-ef4b-44ad-bbde-9e54b45aecc5
Epinephrine added to a solution of lignocaine for a peripheral nerve block will :
Increase risk of convulsions
Increase the duration of action of the local anesthetic
Both (a) and (b)
None of these
1b
multi
null
Pharmacology
null
a0a4a01c-1d4c-48b6-aa74-349433d37e2a
In Patey's mastectomy all the following are removed except
Pectoralis major
Skin of the breast
Pectoralis minor
Ductular system of the breast
0a
multi
Ans. (a) Pectoralis major(Ref. Bailey and Love 26th edition Page 813)Structures removed in Patey's mastectomy:* Breast, nipple, areola including the skin overlying the tumor* Level 1,2,3 Lymphnodes* Fascia over Pectoralis major* Pectoralis minor muscle
Surgery
Breast
6c2fb816-bdbb-4774-89c3-dea2ad19c538
Axis is the name for:
IV cervical vertebra
III cervical vertebra
II cervical vertebra
I cervical vertebra
2c
single
Second cervical vertebra (axis) Presence of odontoid process. Transverse processes are small and lack the anterior tubercle. Anterior margin of the inferior surface of the body projects downwards to a considerable extent. Foramen transversarium is directed superolaterally (expand in typical vertebrae it is directed ve...
Anatomy
null
36d28bf3-f48d-4d2d-9fb4-12eb81ceeaf2
Reed sternberg cells are found in-
Hodkin's disease
Sickle cell anaemia
Thalassemia
CML
0a
single
Hodgkin&;s lymphoma is characterised by the presence of neoplastic giant cells called Reed Sternberg cells.These cells release factors that induce the accumulation of reactive lymphocytes, macrophages, and granulocytes, which typically make up greater than 90% of tumour cellularity. RS cells are derived from the germin...
Pathology
Haematology
57f5085c-5527-4fc7-ac9c-a3802ac8b4b6
16 yr unmarried girl came for vaccination against cervical cancer. Which vaccine to he given:
Gardasil
Rabivac
Biovac
Tvac
0a
single
Ans. (A) Gardasil(Ref: Shaw's Textbook of Gynecology 16th Ed; Page No 495)Gardasil is the vaccine of choice in this situation.Other options:Biovac: It is freeze-dried live attenuated vaccine indicated for the prevention of Hepatitis A in persons of age 1 year or older.Rabivac: It is monovalent inactivated rabies vaccin...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
34b88b65-cb4a-41a1-84b2-001ad9600303
Insulin stimulated glucose entry in seen in-
Cardiac muscles
Smooth muscles
Brain
Intestines
0a
single
Insulin stimulated glucose entry in seen in Cardiac muscles. Name Location Features GLUT-1 & GLUT-3 Brain, RBC, placenta Concerned with basal uptake of glucose GLUT-2 Liver, kidney, b-cells of pancreas Allows both entry & release of glucose GLUT-4 Skeletal muscles, adipocytes, cardiac muscles Insulin dependent transpoe...
Physiology
Endocrine System
ed26d6d3-f7ec-4f41-b26d-3c7793216ff4
Cribriform hymen is seen -
Post paum
Septate hymen
Sieve hymen
Virgin
3d
single
Ref: Textbook of Forensic medicine and toxicology (V.V.Pillay) 17th edition, page no.354 Hymen is a thin fold of connective tissue, covered by mucous membranes, about 1 mm in overall thickness, situated at the vaginal orifice. They are of different types. cribriform is one of them, characterized by many small holes. As...
Forensic Medicine
Sexual offences and infanticide
4fe38f45-7890-4319-8d84-a35d72845b11
A 7 year old child with rheumatic heart disease presents with pallor, fever and a palpable spleen. The following investigations would be needed to arrive at a diagnosis except –
Electrocardiogram
Echocardiogram
Blood culture
Urine examination
0a
multi
null
Pediatrics
null
c23b2919-7b9a-48c2-a54b-eb3a81113fea
In metabolic alkalosis, which Is true about excretion in urine
More of NH3
Less of aceto-acetic acid
Betahydroxy butyric acid
Less ammonia
3d
multi
The NH3 production is greatly increased in metabolic acidosis and negligible in alkalosis. It is also observed that activity of renal glutaminase is enhanced in acidosis. The NH3 mechanism is a valuable device for the conservation of fixed base. Under normal conditions, 30 to 50 mEq of H+ ions are eliminated per day, b...
Biochemistry
Metabolism of protein and amino acid
cc5e1e79-bb47-45d4-8a9c-45b311f7b4ab
In which of the following condition local excision in rectal carcinoma can not be done?
Within 10 cm of the dentate line
Lesion 2.7 cm
Involvement of <30% bowel circumference
T1 and T2 cancer with lymph node involvement
3d
single
Suggested criteria for local excision in rectal cancer: Physical examination Imaging Histology Tumor <3 cm Tumor <30% of bowel circumference Tumor within 15 cm of dentate line Tumor freely mobile Tumor limited to submucosa (T1) No lymph node involvement (N0) Well to moderately differentiated Absence of lymphovascular i...
Surgery
Rectum and anal canal
d8df3767-6a85-49b3-bb28-5ea967bf26fc
Electron microscopy finding indicating irreversible cell injury is:
Dilation of ER
Dissociation of ribosomes from rough ER
Flocculent densities in the mitochondria
Intact cell membrane
2c
single
Irreversible injury is associated morphologically with:- Mitochondrial swelling Plasma membrane damage which forms myelin figures Lysosomal swelling. Large, flocculent, amorphous densities develop in the mitochondrial matrix
Pathology
Irreversible cell Injury/Necrosis
4a753b66-6b14-49a4-882c-783401dc67ea
Which of the following excludes painful stimuli from awareness?
Repression
Reaction formation
Projection
Rationalization
0a
single
Repression is the defense mechanism which removes painful memories or unacceptable desires away from the consciousness or awareness.
Psychiatry
Psychoanalysis
5000f2e2-5e62-4d9e-9020-c40a5218f4b5
Risk factor for suicide -
Female sex
Unmarried
Age 30 years
Married
1b
single
Ans. is 'b' i.e., Unmarried Causes/Risk factors for suicidePsychiatric disorders : - Depression (most common), alcoholism (2nd me), Drug/Substance dependence, Schizophrenia, Dementia.Physical illness : - Cancer, AIDS, Multiple sclerosis, Head trauma.Psychosocial factors : - Failure in love, marital difficulties, family...
Psychiatry
Symptoms & Signs
7328f426-1a4f-473a-972a-531ab59afdd8
At the level of Arch of aoa, the relationship of left vagus nerve and left phrenic nerve?
Phrenic nerve anterior, vagus nerve posterior
Phrenic nerve posterior, vagus nerve anterior
Both in same plane anteroposteriorly
Variable in relationship
0a
multi
Phrenic nerve anterior, vagus nerve posterior
Anatomy
null
a5b2e089-3e8a-490a-9387-74687302149f
ACE inhibitor contraindicated in which of the following condition:
Bilateral renal artery stenosis
Chronic kidney disease
Post myocardial infarction
Diabetes mellitus
0a
single
Ans. (a) Bilateral renal artery stenosisRef. Katzung's pharmacology 10th ed. Ch 11* ACEI inhibits the converting enzyme peptidyl dipeptidase that hydrolyzes angiotensin I to angiotensin II and (under the name plasma kininase) inactivates bradykinin, a potent vasodilator, which works at least in part by stimulating rele...
Pharmacology
ACE Inhibitors
1549adc4-6fcc-48e2-b107-3fd67065e5f5
Nipple retraction in Ca breast due to infiltration of
Suspensory ligaments
Lactiferous ducts
Lymphatics
Pectoralis fascia
1b
single
Answer- B. Lactiferous ductsIt is seen in breast carcinoma due to infltration of the lactiferous ducts by carcinoma.It is due to extention of the growth along the lactiferous ducts and subsequent fibrosis.Nipple retraction is circumferential in carcinoma and slit like in periductal mastitis.
Surgery
null
11762b50-8c60-4a39-be4b-4cbf3aef7640
Regarding spring catarrh, all of the following are true, except:
Cobblestone appearance of conjunctiva
Common in spring months
Limbus conjunctival thickening
Sodium cromoglycate is a form of therapy
2c
multi
Limbus conjunctival thickening
Ophthalmology
null
35e2d662-b0ce-42fb-9bc3-69986cc3e23d
All the following malignancies are associated with HIV, except-
Kaposi's Ca.
Non Hodgkin's lymphoma
Astrocytoma
Gastric adeno Ca.
2c
multi
Ans. is 'c' i.e., Astrocytoma Neoplastic disease in AIDS o Kaposi sarcoma (most common tumor) o Non Hodgkin lymphoma Immunoblastic lymphoma (most common lymphoma) Primary CNS lymphoma (associated with EBV) Burkitt's lymphoma Other less common neoplasm are Hodgkin's disease Leukemia Cervical Ca Brain tumor Testicular Ca...
Pathology
null
e585c7fd-54e4-47dd-883c-67abe196f782
Genetic material is transferred from one bacteria to another by all except
Transduction
Transformation
Transfection
Conjugation
2c
multi
Transfection is the method by which DNA is transferred into eukaryotic cell.
Biochemistry
null
5aa39b7e-ef8a-4d42-85e1-b69eec6d0a99
True about Hodgkin's lymphoma are all except?
Often localized to single axial group of lymph nodes
Hepatomegaly is always present
Contiguous spread of lymph nodes
Can be cured by Chemotherapy and Radiotherapy
1b
multi
HODGKIN'S LYMPHOMA : - HL arises in lymphoid tissue & spreads to adjacent lymph node areas in a relatively orderly fashion. -Patients commonly present with painless, non-tender, firm, rubbery, cervical or supraclavicular lymphadenopathy and usually some degree of mediastinal involvement. HEPATOSPLENOMEGALY IS A FEATURE...
Pediatrics
Neoplastic disorders of WBCs
7e6dd171-f659-4be9-9d53-6fb8ebf8f71c
25 years old female has palatal ulcer and skin blister most likely diagnosis is –
Pemphigus vulgaris
Pemphigus foliaceous
Dermatitis herpetiformis
Pemphigoid
0a
single
Skin blister Oral mucosa involvement (palatal ulcer)
Dental
null
0aa505ac-bc68-40f2-8f61-a292fa8e8201
Concerning contraction of the diaphragm:
The nerves that are responsible emerge from the spinal cord at the level of the lower thorax
It tends to flatten the diaphragm
It reduces the lateral distance between the lower rib margins
It causes the anterior abdominal wall to move in
1b
multi
When the diaphragm contracts, it becomes flatter The phrenic nerves that innervate the diaphragm come from high in the neck, that is, cervical segments 3, 4, and 5. Contraction of the diaphragm causes the lateral distance between the lower rib margins to increase and anterior abdominal wall to move out. The intrapleura...
Physiology
Respiratory System Pa 1
f5955860-aa16-4f19-b13b-5e595e301389
Infants of diabetic mothers are likely to have the following cardiac anomaly:
Coarctation of aorta
Fallot's tetralogy
Ebstein's anomaly
Transposition of great arteries
3d
multi
Ans. is d, i.e. Transposition of great arteriesRef. Fernando Arias 3/e, p 454As VSD is not given in the options, transposition of great vessels is the single best answer.
Gynaecology & Obstetrics
Medical & Surgical Illness Complication Pregnancy
28e73efe-c768-4be7-ad94-d0f3fad85a48
Congo red staining of abdominal fat has confirmed a diagnosis of Amyloidosis in a 28-year-old man. Which is the most common cause of death in primary AL Amylodosis?
Respiratory failure
Cardiac failure
Renal failure
Septicemia
1b
single
Cardiac failure is the most common cause of death in primary or AL amyloidosis. Cardiac involvement is seen in 40% of patients with AL amyloidosis. Amyloid involvement of myocardium, intramural coronary aeries and conduction system may cause congestive hea failure, ischemic syndrome and rythm disturbances. Diagnosis of...
Pathology
null