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Contrast Agent Mass Spectrometry Imaging Reveals Tumor Heterogeneity.
Mapping intratumoral heterogeneity such as vasculature and margins is important during intraoperative applications. Desorption electrospray ionization mass spectrometry (DESI-MS) has demonstrated potential for intraoperative tumor imaging using valid... | {
"pile_set_name": "PubMed Abstracts"
} |
Stent migration complicating treatment of inferior vena cava stenosis after orthotopic liver transplantation.
A case of inferior vena cava (IVC) stenosis after orthotopic liver transplantation was treated with balloon angioplasty and Wallstent placement. There was stent migration into the right atrium (RA), and percuta... | {
"pile_set_name": "PubMed Abstracts"
} |
Tryptophan metabolism: utility of plasmatic assay in phenylketonuria, a study in 6 adult patients.
Phenylketonuria (PKU, OMIM 261600) is an autosomal recessive inborn error of metabolism caused by a deficiency of the hepatic enzyme phenylalanine hydroxylase (PAH; EC 1.14.16.1). If untreated, the disease leads to an imp... | {
"pile_set_name": "PubMed Abstracts"
} |
Correction: The dilemma in prioritizing chemicals for environmental analysis: known versus unknown hazards.
Correction for 'The dilemma in prioritizing chemicals for environmental analysis: known versus unknown hazards' by Anna Sobek et al., Environ. Sci.: Processes Impacts, 2016, DOI: 10.1039/c6em00163g. | {
"pile_set_name": "PubMed Abstracts"
} |
Exfoliative dermatitis: presenting sign of internal malignancy.
Exfoliative dermatitis is most commonly associated with antecedent cutaneous disorders, medications, and lymphoreticular malignancies. Three patients with exfoliative dermatitis associated with internal carcinoma are described. The importance of thorough e... | {
"pile_set_name": "PubMed Abstracts"
} |
Impact of narrow-band imaging in screening colonoscopy.
Narrow band-imaging (NBI) enhances mucosal visualization of the vascular network and surface structure and helps to increase the visibility of neoplasia by improving contrast. Studies on the detectability of colorectal neoplastic lesions using NBI have primarily b... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of a single pentagastrin injection on diamine oxidase activity in the rat intestinal mucosa.
The effect of a single injection of pentagastrin on diamine oxidase (DAO) activity in the rat intestinal mucosa was examined. The animals of subsequent groups were sacrificed by decapitation at 6, 12 and 24 h after the ... | {
"pile_set_name": "PubMed Abstracts"
} |
Isolation of inclusion bodies from vegetative Clostridium perfringens: partial purification of a 47 kDa inclusion protein.
A refractile inclusion body produced by vegetative cells of Clostridium perfringens at temperatures above 40 degrees C was isolated and partially characterized. The inclusion was composed of protei... | {
"pile_set_name": "PubMed Abstracts"
} |
Polymer optical fiber Bragg grating acting as an intrinsic biochemical concentration sensor.
We demonstrate an intrinsic biochemical concentration sensor based on a polymer optical fiber Bragg grating. The water content absorbed by the polymer fiber from a surrounding solution depends on the concentration of the soluti... | {
"pile_set_name": "PubMed Abstracts"
} |
Oxidative stress developed during open heart surgery induces apoptosis: reduction of apoptotic cell death by ebselen, a glutathione peroxidase mimic.
Apoptosis, a genetically controlled programmed cell death, has been found to play a role in ischemic reperfusion injury in several animal species including rats and rabbi... | {
"pile_set_name": "PubMed Abstracts"
} |
Barriers to supported education implementation: implications for administrators and policy makers.
The economic impact of a lack of educational achievement for individuals with psychiatric disabilities is profound. Current poor economic conditions exacerbate the effects of low educational levels. This article presents ... | {
"pile_set_name": "PubMed Abstracts"
} |
Prepulse inhibition of the blink reflex is abnormal in functional movement disorders.
Patients with functional movement disorders also typically have functional somatic symptoms, including pain, fatigue, and sensory disturbance. A potentially unifying mechanism for such symptoms is a failure in processing of sensory in... | {
"pile_set_name": "PubMed Abstracts"
} |
Creating certainty and confidence with indirect bonding.
Indirect bonding offers a superior method of adhering brackets to teeth, but few orthodontists use it. The neglect of this procedure has many origins, including expense, lack of expertise, and inconsistent results. This paper presents an indirect-bonding method t... | {
"pile_set_name": "PubMed Abstracts"
} |
FTZ-F1 and FOXL2 up-regulate catfish brain aromatase gene transcription by specific binding to the promoter motifs.
Cytochrome P450 aromatase (cyp19) catalyzes the conversion of androgens into estrogens. Teleosts have distinct, ovarian specific (cyp19a1a) and brain specific (cyp19a1b) cyp19 genes. Previous studies in t... | {
"pile_set_name": "PubMed Abstracts"
} |
Cyclic AMP and ethanol interact to control apoptosis and differentiation in hypothalamic beta-endorphin neurons.
In this study we have determined the role of cyclic AMP on the function and differentiation of beta-endorphin (beta-EP) neurons in rat fetal hypothalamic cell cultures. Addition of Bt2cAMP or the cAMP elevat... | {
"pile_set_name": "PubMed Abstracts"
} |
[Alcohol's impact on children and families. A population survey].
Alcohol is widely used among young families, and leisure time is frequently family time. Heavy alcohol consumption can adversely affect children. The objective of this work is to measure the harm to others in Chile. This descriptive and probabilistic stu... | {
"pile_set_name": "PubMed Abstracts"
} |
Prognostic factors in patients undergoing complete resection of pulmonary metastases of colorectal cancer: a multi-institutional cumulative follow-up study.
The aim of this retrospective study was to establish the prognostic factors for overall survival after pulmonary resection for lung metastases of colorectal carcin... | {
"pile_set_name": "PubMed Abstracts"
} |
Experimental spike-and-wave discharges induced by pentylenetetrazol and tolerance to repeated injections: an electrophysiological and biochemical study.
This study was designed to obtain experimental data to correlate duration of spike-and-wave (SW) paroxysms with levels of pentylenetetrazol (PTZ) in several brain regi... | {
"pile_set_name": "PubMed Abstracts"
} |
Possible role of endogenous histamine in mediation of LPS-induced secretion of corticosterone in mice.
Escherichia coli lipopolysaccharide (LPS) induced a strong secretion of corticosterone in C3H/HeN mice with a concomitant increase in the splenic histidine decarboxylase activity. Treatment of the mice with alpha-fluo... | {
"pile_set_name": "PubMed Abstracts"
} |
Discrete dinuclear complex to extended 2D compound in a Cu-azido system by controlling coligand stoichiometry: synthesis and magneto-structural correlations.
This article describes syntheses, structural characterizations and magnetic studies of two different Cu(II)-azido compounds, a discrete dinuclear complex and an e... | {
"pile_set_name": "PubMed Abstracts"
} |
Generation of lipoxygenase metabolites of arachidonic acid by monolayer cultures of tracheal epithelial cells and intact tracheal segments from rabbits.
We compared the profile of lipoxygenase metabolites of arachidonic acid (AA) generated by cultured rabbit tracheal epithelial (TE) cells with that produced by intact r... | {
"pile_set_name": "PubMed Abstracts"
} |
Kinetics of low density lipoprotein interactions with rabbit aortic wall following balloon catheter deendothelialization.
The kinetics of the interaction of circulating lipoproteins with the balloon catheter-injured aortic wall of rabbits were investigated. The fate of radioiodinated low density lipoprotein (LDL) was f... | {
"pile_set_name": "PubMed Abstracts"
} |
γ irradiation with different dose rates induces different DNA damage responses in Petunia x hybrida cells.
In plants, there is evidence that different dose rate exposures to gamma (γ) rays can cause different biological effects. The dynamics of DNA damage accumulation and molecular mechanisms that regulate recovery fro... | {
"pile_set_name": "PubMed Abstracts"
} |
Proteomic approaches in neuroblastoma: a complementary clinical platform for the future.
Neuroblastoma (NB) is one of the most common solid tumors of childhood and displays a remarkable diversity in both biologic characteristics and clinical outcomes. Availability of high-throughput 'omics technologies and their subseq... | {
"pile_set_name": "PubMed Abstracts"
} |
Differentiated cervical intraepithelial neoplasia-associated invasive cervical squamous cell carcinoma as a source of major cytopathological and surgical pathological discrepancy in Papanicolaou smear screening tests.
Differentiated cervical intraepithelial neoplasia (dCIN) analogous to differentiated squamous intraepi... | {
"pile_set_name": "PubMed Abstracts"
} |
CSF 5-HIAA and exposure to and expression of interpersonal violence in suicide attempters.
Serotonin is implicated in impaired impulse control, aggression and suicidal behaviour. Low cerebrospinal fluid (CSF) concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) have been found in violent suici... | {
"pile_set_name": "PubMed Abstracts"
} |
Homocysteine thiolactone inhibits insulin signaling, and glutathione has a protective effect.
Hyperhomocysteinemia and insulin resistance are independent factors for cardiovascular disease. Most of the angiotoxic effects of homocysteine are related to the formation of homocysteine thiolactone and the consequent increas... | {
"pile_set_name": "PubMed Abstracts"
} |
Endometrial response to unopposed estrogens remains unaltered in patients with chronic renal failure receiving hemodialysis.
Most patients with chronic renal failure who are on maintenance hemodialysis are anovulatory and have menstrual abnormalities. This study was designed to determine the prevalence of organic cause... | {
"pile_set_name": "PubMed Abstracts"
} |
Early use of immunosuppressives or TNF antagonists for the treatment of Crohn's disease: time for a change.
Crohn's disease is a chronic inflammatory disorder that follows a progressive and destructive course. Ultimately, uncontrolled inflammation leads to bowel damage from disease-related complications such as strictu... | {
"pile_set_name": "PubMed Abstracts"
} |
Diminished material properties and altered bone structure in rat femora during pregnancy.
Pregnancy and lactation are known to cause structural and mechanical changes in bone, but the effects of pregnancy alone have not been evaluated thoroughly. This study used radiographic measurements, torsion testing, mineral analy... | {
"pile_set_name": "PubMed Abstracts"
} |
Availability, affordability, and consumption of fruits and vegetables in 18 countries across income levels: findings from the Prospective Urban Rural Epidemiology (PURE) study.
Several international guidelines recommend the consumption of two servings of fruits and three servings of vegetables per day, but their intake... | {
"pile_set_name": "PubMed Abstracts"
} |
Follicle cell development is partly independent of germ-line cell differentiation in Drosophila oogenesis.
The developmental potential of the cells of the somatic follicular epithelium (follicle cells) was studied in mutants in which the differentiation of the germ-line cells is blocked at different stages of oogenesis... | {
"pile_set_name": "PubMed Abstracts"
} |
Sorting of B lymphoblasts based upon cell diameter provides cell populations enriched in different stages of cell cycle.
Here we report analysis and correlation of changes in cell size and cycle state resulting from exposure of murine B lymphocytes to the mitogens lipopolysaccharide (LPS) and dextran sulfate (DxSO4). C... | {
"pile_set_name": "PubMed Abstracts"
} |
Getting your research published: adapting the thesis style.
Writing a research report is similar to the research experience; both are processes with many distinct steps. Break your research project into parts and write about key accomplishments as you complete each milestone in the project. | {
"pile_set_name": "PubMed Abstracts"
} |
The quantitative alteration of 5s rRNA during the development of mammalian erythroid cells and its effect on DNA synthesis in SP2/0 mouse myeloma cells.
Mouse myeloma cells (SP2/0) were incubated with 125I-5s rRNA from rabbit reticulocytes and processed for autoradiography. The results indicated that 5s rRNA could pass... | {
"pile_set_name": "PubMed Abstracts"
} |
Validation of a targeted DNA microarray for the clinical evaluation of recurrent abnormalities in chronic lymphocytic leukemia.
Recurrent genomic alterations, mainly losses and gains of specific chromosomes and/or regions, in chronic lymphocytic leukemia (CLL) are recognized as important independent predictors of progn... | {
"pile_set_name": "PubMed Abstracts"
} |
Small intestinal bacterial overgrowth: diagnosis and treatment.
Small intestinal bacterial overgrowth (SIBO) is a clinical condition characterized by a malabsorption syndrome due to an increase in microorganisms within the small intestine. The main mechanisms restricting bacterial colonization in the upper gut are the ... | {
"pile_set_name": "PubMed Abstracts"
} |
Molecular and functional characterization of pigeon (Columba livia) tumor necrosis factor receptor-associated factor 3.
Tumor necrosis factor receptor-associated factor 3 (TRAF3) plays a key antiviral role by promoting type I interferon production. We cloned the pigeon TRAF3 gene (PiTRAF3) according to its predicted mR... | {
"pile_set_name": "PubMed Abstracts"
} |
Concurrent increase of oxidative DNA damage and lipid peroxidation together with mitochondrial DNA mutation in human lung tissues during aging--smoking enhances oxidative stress on the aged tissues.
Although mutation of mitochondrial DNA (mtDNA) in human tissues has been established to associate with intrinsic aging, t... | {
"pile_set_name": "PubMed Abstracts"
} |
Focusing on outcomes and methods in removable prosthodontics trials: a systematic review.
The aim of this study was to systematically examine the outcomes of interest of trials in removable prosthodontics and to assess their overall quality. Electronic databases were searched up to August 2011 and complemented by hand ... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of solvent exposure on testosterone levels and butyrylcholinesterase activity in mice.
In female and male mice the effect of exposure to trichloroethylene (TCE) seen at the lowest concentration is an increase in liver weight. The activity of plasma butyrylcholinesterase (BuChE) increases even more than the live... | {
"pile_set_name": "PubMed Abstracts"
} |
Patterns of splenic arterial enhancement on computed tomography are related to changes in portal venous pressure.
One of the striking features of splenic imaging is variable heterogeneous gyriform arterial enhancement on dynamic computed tomography (CT). We speculated that these patterns of arterial enhancement may ref... | {
"pile_set_name": "PubMed Abstracts"
} |
Impact of student pharmacist-led naloxone academic detailing at community pharmacies in Texas.
Each U.S. state and the District of Columbia has passed legislation expanding access to naloxone, the opioid overdose antidote. Most naloxone access laws allow for standing orders, whereby prescribers may authorize pharmacist... | {
"pile_set_name": "PubMed Abstracts"
} |
Significance of molecular signaling for protein translation control in neurodegenerative diseases.
It has long been known that protein synthesis is inhibited in neurological disorders. Protein synthesis includes protein transcription and translation. While many studies about protein transcription have been done in the ... | {
"pile_set_name": "PubMed Abstracts"
} |
A grouped retina provides high temporal resolution in the weakly electric fish Gnathonemus petersii.
Weakly electric fish orient, hunt and communicate by emitting electrical pulses, enabling them to discriminate objects, conspecifics and prey. In addition to the electrosensory modality - although dominating in importan... | {
"pile_set_name": "PubMed Abstracts"
} |
Abdominal angina and intestinal gangrene--a catastrophic presentation of arterial fibromuscular dysplasia: case report and review of the literature.
A 5-year-old boy presented with episodic, postprandial abdominal pain and hypertension. A few days after the onset of symptoms, the pain became more severe, and progressed... | {
"pile_set_name": "PubMed Abstracts"
} |
Jugular foramen syndrome.
The jugular foramen syndrome (JFS) specifically refers to paralysis to the IX-XIth cranial nerves. In a more general meaning, however, any combination of palsies affecting the last four cranial nerves has been referred to as a JFS. The anatomy of the jugular foramen and the structures which tr... | {
"pile_set_name": "PubMed Abstracts"
} |
Antibodies in Escherichia coli urinary tract infection.
In 105 adults with E.Coli urinary tract infections, IgG coated bacteriuria was found in 8/9 with acute pyelonephritis (PN), 17/20 with chronic PN, and in only 2/76 with lower UTI. IgA was present in 66% of PN, but IgA secretory piece in less than 10%. These urinar... | {
"pile_set_name": "PubMed Abstracts"
} |
African trypanosomiasis: naturally occurring regulatory T cells favor trypanotolerance by limiting pathology associated with sustained type 1 inflammation.
Tolerance to African trypanosomes requires the production of IFN-gamma in the early stage of infection that triggers the development of classically activated macrop... | {
"pile_set_name": "PubMed Abstracts"
} |
Incarcerated Women's Experiences and Perceptions of Participating in Research.
The research process within prisons has largely considered researchers' perspectives. Only one known study explicitly examined incarcerated persons' perceptions and no known studies have explored incarcerated persons' experiences with resear... | {
"pile_set_name": "PubMed Abstracts"
} |
The relationship between fast bowling workload and injury in first-class cricketers: a pilot study.
This study examined the relationship between the bowling workload of first-class fast bowlers and injury with the aim of identifying a "safe" fast bowling workload threshold. Twelve male fast bowlers (mean age 25 years) ... | {
"pile_set_name": "PubMed Abstracts"
} |
A scoring framework for assessing anatomy competence of undergraduate preclinical students.
Recent higher education changes toward outcomes-based education emphasize competent learners, but a widely accepted definition of competence is still lacking. Although the importance of anatomy in health professions education is... | {
"pile_set_name": "PubMed Abstracts"
} |
[Hyperechogenic fetal bowel as a marker of fetal cystic fibrosis].
Hyperechogenic bowel (HB) occurs in 0.1 to 1.8% of normal pregnancies. In most cases it has no consequence for the foetus, but can be associated with cystic fibrosis (CF), chromosomal defects, genetic syndromes, viral infections, gastrointestinal pathol... | {
"pile_set_name": "PubMed Abstracts"
} |
Gamma irradiation effects on stability of poly(lactide-co-glycolide) microspheres containing clonazepam.
This work was aimed at evaluating the effects of gamma irradiation on the stability of microspheres made of a poly(lactide-co-glycolide) copolymer (PLGA) and loaded with 15% w/w of clonazepam (CLO). The influence of... | {
"pile_set_name": "PubMed Abstracts"
} |
The use of transducer-tipped ultrasound catheter for recanalization of thrombotic arterial occlusions.
Ultrasound energy is currently being used and intensively investigated for recanalization of thrombotically occluded arteries. The ultrasonic energy is mainly applied either by a transcutaneous approach or by a percut... | {
"pile_set_name": "PubMed Abstracts"
} |
Damage control resuscitation.
Damage Control Resuscitation (DCR) is a novel concept that draws together a series of technical and organisational advances in combat casualty care. It is consistent with and encapsulates the established concept of damage control surgery (DCS). | {
"pile_set_name": "PubMed Abstracts"
} |
Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects.
While opioids are potent analgesics widely used in the management of pain, a number of well-known adverse effects limit their use. The sigma-1 receptor is a ligand-regulated molecular chape... | {
"pile_set_name": "PubMed Abstracts"
} |
Interaction of Shiga toxin from Escherichia coli with human intestinal epithelial cell lines and explants: Stx2 induces epithelial damage in organ culture.
Shiga toxins (Stx) produced by Escherichia coli are associated with systemic complications such as haemolytic-uraemic syndrome. The mechanism of Stx translocation a... | {
"pile_set_name": "PubMed Abstracts"
} |
Dose-dependent effect of rosuvastatin in the regulation of metalloproteinase expression.
The importance of rosuvastatin at therapeutic dosage in regulating the release, activity, protein level, and expression of matrix metalloproteinases (MMP)-2 and MMP-9 was investigated. Human umbilical artery smooth muscle cells wer... | {
"pile_set_name": "PubMed Abstracts"
} |
Primary precutting versus conventional over-the-wire sphincterotomy for bile duct access: a prospective randomized study.
Precut is a well-known technique that is used if repeated attempts at common bile duct (CBD) cannulation fail. Opinions on the complication rate of precut are conflicting, however. The aim of the pr... | {
"pile_set_name": "PubMed Abstracts"
} |
Added benfluorex in obese insulin-requiring type 2 diabetes.
To determine the effect of benfluorex on glycaemic control in obese insulin-requiring Type 2 diabetes, 76 patients (aged 53.8 +/- 12.8 years) receiving insulin (> or = 0.5 IU/kg) and an appropriate low-calorie diet were evaluated after a 1-month run-in follow... | {
"pile_set_name": "PubMed Abstracts"
} |
[History and medicine: the inheritance of an age-old paradigm].
Based on inheritance of a common model of knowledge, drawing links between history and medicine represents a proposal to not abandon the contribution the past has to make when reflecting upon the current stage of scientific production in both fields. With ... | {
"pile_set_name": "PubMed Abstracts"
} |
Fluorous hydroformylation.
The application of fluorous phosphine-modified catalysts for the hydroformylation of olefins is reviewed. | {
"pile_set_name": "PubMed Abstracts"
} |
Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats.
Ischemia and reperfusion are of the greatest importance in the pathology of many diseases. We investigated the roles of oxygen-derived free radicals and lipid peroxidation in gastric mucosal injury, such as s... | {
"pile_set_name": "PubMed Abstracts"
} |
Understanding the basis of Ehlers-Danlos syndrome in the era of the next-generation sequencing.
Ehlers-Danlos syndrome (EDS) is a clinically and genetically heterogeneous group of heritable connective tissue disorders (HCTDs) defined by joint laxity, skin alterations, and joint hypermobility. The latest EDS classificat... | {
"pile_set_name": "PubMed Abstracts"
} |
Genetic strain differences in the development of peritoneal fibroproliferative processes in mice.
Fibroproliferative processes are regulated by a wide variety of tissue components and genetic factors. However, whether there are genetic differences in peritoneal fibroproliferative tissue formation, with consequent diffe... | {
"pile_set_name": "PubMed Abstracts"
} |
Vertebroplasty for the treatment of osteoporotic compression spinal fracture: comparison of remedial action at different stages of injury.
Outstanding results have been achieved using vertebroplasty for the treatment of osteoporotic compression spinal fractures, and a number of studies have reported the results from th... | {
"pile_set_name": "PubMed Abstracts"
} |
Association of number of positive nodes and cervical stroma invasion with outcome of advanced endometrial cancer treated with chemotherapy or whole abdominal irradiation: a Gynecologic Oncology Group study.
To determine whether the number of positive pelvic nodes (PPN), cervical stromal involvement (CSI), and/or lympho... | {
"pile_set_name": "PubMed Abstracts"
} |
Two-dimensional electrophoresis of human urinary proteins following concentration by dye precipitation.
The use of dye precipitation for concentration of proteins prior to 2-DE has been demonstrated by application to human urine. The precipitation methods (T. Marshall and K. M. Williams, Clin. Chem. 1993, 39, 2314-2318... | {
"pile_set_name": "PubMed Abstracts"
} |
Glutamine attenuates hyperoxia-induced acute lung injury in mice.
1. Glutamine is an amino acid that is used to treat various diseases. Glutamine has been reported to have protective effects in human pulmonary epithelia-like cells exposed to hyperoxia. However, the effects of glutamine in hyperoxia-induced lung injury ... | {
"pile_set_name": "PubMed Abstracts"
} |
[Revascularization of the distal vertebral artery (3d segment). Indications in the treatment of vertebrobasilar insufficiency].
This article reviews 11 cases of distal revascularization of the extracranial vertebral artery above C2. Revascularization was indicated in 7 cases of extensive atheromatous stenotic or occlus... | {
"pile_set_name": "PubMed Abstracts"
} |
Transmission dynamics of two dengue serotypes with vaccination scenarios.
In this work we present a mathematical model that incorporates two Dengue serotypes. The model has been constructed to study both the epidemiological trends of the disease and conditions that allow coexistence in competing strains under vaccinati... | {
"pile_set_name": "PubMed Abstracts"
} |
Introducing a Gene Knockout Directly Into the Amastigote Stage of Trypanosoma cruzi Using the CRISPR/Cas9 System.
Trypanosoma cruzi is a pathogenic protozoan parasite that causes Chagas' disease mainly in Latin America. In order to identify a novel drug target against T. cruzi, it is important to validate the essential... | {
"pile_set_name": "PubMed Abstracts"
} |
Parental Vigilance in Caring for Their Children with Hypoplastic Left Heart Syndrome.
Hypoplastic left heart syndrome (HLHS) is a complex heart malformation that requires life-saving treatments. Parents experience numerous challenges as they learn to parent a child with complex care requirements. The following research... | {
"pile_set_name": "PubMed Abstracts"
} |
Potential therapeutic use of antibodies directed towards HuIFN-gamma.
IFN-gamma is an important regulator of immune responses and inflammation. Studies in animal models of inflammation, autoimmunity, cancer, transplant rejection and delayed-type hypersensitivity have indicated that administration of antibodies against ... | {
"pile_set_name": "PubMed Abstracts"
} |
Simvastatin inducing PC3 prostate cancer cell necrosis mediated by calcineurin and mitochondrial dysfunction.
In the present study we analyzed the mechanisms of simvastatin toxicity for the PC3 human prostate cancer cell line. At 10 microM, simvastatin induced principally apoptosis, which was prevented by mevalonic aci... | {
"pile_set_name": "PubMed Abstracts"
} |
Excimer-monomer switch: a reaction-based approach for selective detection of fluoride.
A N-aryl-1,8-naphthalimide based sensor (ES-1) bearing a trimethylsilyl ether has been synthesized by a two-step reaction for quantitative detection of fluoride (F(-)). ES-1 exhibited monomer/excimer emissions at 410 and 524 nm respe... | {
"pile_set_name": "PubMed Abstracts"
} |
Lanthanide metal-organic frameworks: searching for efficient solvent-free catalysts.
Three Ln-based 2D metal-organic frameworks with the formula [Ln(3,5-DSB)(Phen)] (Ln = La, Pr, Nd; 3,5-DSB = 3,5-disulfobenzoate; Phen = 1,10-phenathroline) were hydrothermally synthesized. They belong to two 2D structural types, and th... | {
"pile_set_name": "PubMed Abstracts"
} |
Guillain-Barré syndrome associated with CASPR2 antibodies: two paediatric cases.
The pathogenesis of Guillain-Barré syndrome (GBS) is considered to be, at least in part, mediated by autoantibodies directed against neuronal antigens. Antibodies to contactin-associated protein-like 2 (CASPR2), part of the voltage-gated p... | {
"pile_set_name": "PubMed Abstracts"
} |
Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomics analysis.
Enhanced lipid peroxidation is well established in traumatic brain injury. However, its molecular targets, identity of peroxidized phospholipid species, and their signaling role have not been deciphered. Using contr... | {
"pile_set_name": "PubMed Abstracts"
} |
Vascular function and arginine and dimethylarginines in gentamicin-induced renal failure: a possible effect of heme oxygenase 1 inducer hemin.
Increased oxidative stress and disturbance in nitric oxide bioavailability lead to endothelial dysfunction and cardiovascular complication in renal disease. Gentamicin (GM), a c... | {
"pile_set_name": "PubMed Abstracts"
} |
[Independent lung ventilation during general anaesthesia--preliminary report].
Unitaleral lung pathology presents a serious challenge for the anaesthesiologist. Conventional ventilation usually leads to over distension of the non-affected lung and hypoventilation of the affected lung. The optimal ventilatory strategy i... | {
"pile_set_name": "PubMed Abstracts"
} |
Neurohormones and heart failure: the importance of aldosterone.
Heart failure is a major cause of cardiovascular morbidity and mortality and its incidence is on the increase. The pathophysiology of heart failure is multi-factorial but recent studies suggest that aldosterone plays an important and independent role in it... | {
"pile_set_name": "PubMed Abstracts"
} |
Adult post-traumatic stress disorder: screening and treating in primary care.
Trauma and post-traumatic stress disorder (PTSD) affect patients' physical health and daily functioning. Primary care physicians should remember to screen for trauma history and symptoms of PTSD when patients present with somatization, chroni... | {
"pile_set_name": "PubMed Abstracts"
} |
Expression of PEA3 and lack of correlation between PEA3 and HER-2/neu expression in breast cancer.
The ETS protein PEA3 functions as a transcription factor to regulate gene expression. Although members of the ETS family have been reported to be involved in tumor progression, ectopic expression of PEA3 has been shown to... | {
"pile_set_name": "PubMed Abstracts"
} |
Peptide deformylase inhibitors with non-peptide scaffold: synthesis and structure-activity relationships.
Peptide deformylase (PDF), which removes the formyl group at the N-terminal methionine residue of nascent protein, has been recognized as a potent target for antibacterial therapy. We report herein the synthesis an... | {
"pile_set_name": "PubMed Abstracts"
} |
Proclamation No. 214, 3 February 1988.
This Proclamation declares the second week of February 1988 and every year thereafter as Respect and Care for Life Week. The text of the Proclamation, including its preamble, is as follows: "Whereas, the UN Declaration on Rights of the Child provides that 'the Child, by reason of ... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of acupuncture on the levels of endothelin, TXB2, and 6-keto-PGF1 alpha in apoplexy patients.
In order to delve into the mechanism governing the treatment of apoplexy by acupuncture at yangming channel points as main points, we observed the changes in the endothelin (ET) level in plasma, TXB2 and 6-Keto-PGF1 al... | {
"pile_set_name": "PubMed Abstracts"
} |
Clinical and epidemiological significance of species identification of coagulase-negative staphylococci in a microbiological laboratory.
Although coagulase-negative staphylococci have been implicated in certain human infections, they are generally regarded as contaminants and their clinical significance has been questi... | {
"pile_set_name": "PubMed Abstracts"
} |
[Biomechanical analysis through numerical simulation of rupture of the tibial posterior tendon in valgus flat foot: a cadeveric study].
The insufficiency of the posterior tibial tendon is the most common acquired cause of pain related to valgus flatfoot deformity in adults. The acquired flatfoot adult is a very painful... | {
"pile_set_name": "PubMed Abstracts"
} |
Epstein-Barr virus related central nervous system lymphoma in a child after renal transplantation.
In this report, we describe the development of a rapidly progressive Epstein-Barr virus (EBV) related cerebral lymphoma in an 11 year old girl, eight months after renal transplantation. No serological evidence for a persi... | {
"pile_set_name": "PubMed Abstracts"
} |
Rapid changes in metabolic cold defense and GDP binding to brown adipose tissue mitochondria of rat pups.
To determine developmental changes of brown adipose tissue (BAT) thermogenic activity at defined circadian and thermal states, we evaluated the time course of cold-induced increases of in vitro guanosine 5'-diphosp... | {
"pile_set_name": "PubMed Abstracts"
} |
Obliteration of a coronary artery aneurysm with a PTFE-covered stent: endoluminal graft for coronary disease revisited.
This is the first reported use of the JOSTENT stent graft for aneurysm disease in native coronaries. Consideration can be given to using this polytetrafluoroethylene (PTFE)-covered stent in situations... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of selection for postweaning gain on testicular function in mice.
Changes in testicular and epididymal function and selected endocrine organ size were examined in a line of mice selected for rapid postweaning gain (M16) and in reciprocal crosses with an unselected pedigree control line (ICR). The larger body we... | {
"pile_set_name": "PubMed Abstracts"
} |
Subarachnoid hemorrhage without detectable aneurysm. A review of the causes.
In 15% to 20% of patients with a spontaneous subarachnoid hemorrhage, no aneurysm is found on the first angiogram. This review emphasizes that this group of patients is in fact heterogeneous and describes the clinical features, pattern of hemo... | {
"pile_set_name": "PubMed Abstracts"
} |
Blood rheology and oxygen uptake.
Continuously measured oxygen uptake during constant work exercise (15' 50W) reveals increasing oxygen consumption in individuals with elevated blood viscosity parameters, indicating persistent contribution of anaerobic glycolysis during steady state exercise far below expected "anaerob... | {
"pile_set_name": "PubMed Abstracts"
} |
Fear during labor.
The aims of the present study were to compare primiparous and multiparous women's experiences of fear of delivery during an early stage of active labor (cervix dilatation 3-5 centimeters) and to study whether fear of delivery, measured during the early stage of active labor, was a predictor of the am... | {
"pile_set_name": "PubMed Abstracts"
} |
Toxic anterior segment syndrome following penetrating keratoplasty.
To describe an outbreak of toxic anterior segment syndrome (TASS) following penetrating keratoplasty (PK) and to examine its possible causes. Owing to a series of TASS following PK between June 6, 2007, and October 2, 2007, we reviewed the records of a... | {
"pile_set_name": "PubMed Abstracts"
} |
[Therapeutic bath and Alzheimer's disease].
To safeguard the quality of life of people suffering from Alzheimer's by the creation of an individual care plan, by identifying pleasurable activities or fond memories of the individual, thereby restoring a sense of present well being. The therapeutic bath, an action which m... | {
"pile_set_name": "PubMed Abstracts"
} |
Plasma aldosterone and cortisol levels in experimental acute renal failure.
Deranged adrenal cortical function was previously described in different stress situations. The aim of this work was to study the plasma cortisol and aldosterone levels in acute renal failure induced by the uranyl nitrate injection or bilateral... | {
"pile_set_name": "PubMed Abstracts"
} |
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