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Local control following therapeutic nodal dissection for melanoma.
Regional recurrence of melanoma is usually treated with surgical resection alone. Unfortunately sites of failure following surgical resection are poorly documented. Little information exists regarding local failure following surgery. In order to define ... | {
"pile_set_name": "PubMed Abstracts"
} |
Two components of GABA-induced currents in catfish retinal horizontal cells.
In cone-driven horizontal cells dissociated from the catfish retina, we recorded GABA-induced currents by using a whole-cell voltage-clamp technique. The current consisted of two components. The major component was blocked by picrotoxin, but n... | {
"pile_set_name": "PubMed Abstracts"
} |
Tracheal morphology in patients with tracheomalacia: prevalence of inspiratory lunate and expiratory "frown" shapes.
To identify the spectrum of tracheal morphologies in patients with tracheomalacia, and to determine the prevalence of specific inspiratory (lunate) and expiratory (frown) shapes that have been associated... | {
"pile_set_name": "PubMed Abstracts"
} |
Morphological characteristics of styloid process evaluated by computerized axial tomography.
Morphological characteristics of styloid process and ossified stylohyoid ligament and their overall relationships to age and sex were studied by using computerized axial tomography images. The styloid process and ossified stylo... | {
"pile_set_name": "PubMed Abstracts"
} |
Observational study of job satisfaction in hospital pharmacy technicians.
Intrinsic and extrinsic factors contributing to job satisfaction of pharmacy technicians in two community hospitals were studied. A pharmacy student employed part-time as a pharmacy technician by one of the hospitals observed fellow technicians i... | {
"pile_set_name": "PubMed Abstracts"
} |
Cloning and expression of cynomolgus monkey and baboon zona pellucida proteins.
Partial clones for the three cynomolgus monkey (Macaca fasicularis) zona pellucida genes (cmZPA, cmZPB, and cmZPC) have previously been isolated. These partial clones contained the sequences for the C-terminal portion of each rcmZP protein.... | {
"pile_set_name": "PubMed Abstracts"
} |
Association between angiotensin-converting enzyme gene polymorphisms and QT duration in a multiethnic population in Hawaii.
Recent studies have suggested that heart-rate corrected QT interval (QTc) in normal populations may be influenced by genetic factors. We report findings of a study of the relationship between QTc,... | {
"pile_set_name": "PubMed Abstracts"
} |
[Metabolic activity of Krebs cycle in the liver during experimental burns].
Metabolic capacity of the Krebs cycle was limited in liver tissue of rats with experimental thermic burns of the IIIa-IIIb grade, involving 25-30% of a body surface; the phenomenon was primarily manifested in a decrease in the citrate synthesis... | {
"pile_set_name": "PubMed Abstracts"
} |
Monoclonal antibody-based fluorescence polarization immunoassay for sulfamethoxypyridazine and sulfachloropyridazine.
In this paper, a new monoclonal antibody (Mab) against sulfamethoxypyridazine (SMP) was produced, and a fluorescence polarization immunoassay (FPIA) based on the produced Mab was developed and optimized... | {
"pile_set_name": "PubMed Abstracts"
} |
SEM examination of human erythrocytes in uncoated bloodstains on stone: use of conventional as environmental-like SEM in a soft biological tissue (and hard inorganic material).
Although nowadays the so-called environmental scanning electron microscopes (ESEMs) allow the observation of the samples without metal or carbo... | {
"pile_set_name": "PubMed Abstracts"
} |
Dose-intensified chemoradiation is associated with altered patterns of failure and favorable survival in patients with newly diagnosed glioblastoma.
We evaluated whether dose-intensified chemoradiation alters patterns of failure and is associated with favorable survival in the temozolomide era. Between 2003 and 2015, 8... | {
"pile_set_name": "PubMed Abstracts"
} |
Surgical correction of severe hammer digit syndrome: a case report.
Survivors of a stroke are forever in a battle for complete recovery. Signs and symptoms of the initial stroke may remain. Patients who has had a stroke may retain some of their initial manifestations, e.g., hemiparesis. Limbs that were initially paraly... | {
"pile_set_name": "PubMed Abstracts"
} |
The bone-anchor sub-urethral sling for the treatment of iatrogenic male incontinence: subjective and objective assessment after 41 months of mean follow-up.
To evaluate retrospectively the objective and subjective parameters in 42 male patients who underwent bone anchored sub-urethral sling positioning (BAUS) for SUI (... | {
"pile_set_name": "PubMed Abstracts"
} |
Hemodynamic tolerance and pharmacokinetics of nicorandil in experimental heart failure.
We tested whether nicorandil (NCR), a nitrovasodilator which also possesses K+ channel action, will produce in vivo hemodynamic tolerance commonly observed with other nitrovasodilators such as nitroglycerin (NTG). NCR was infused at... | {
"pile_set_name": "PubMed Abstracts"
} |
Thalassemia-like phenotype in a novel complex hemoglobinopathy with α, β, δ globin chain abnormalities.
The occurrence of multiple abnormalities of α, β, δ, and γ globin genes may lead to unusual and complex phenotypes when they arise simultaneously in the same individual. Here, we report the findings of an African Ame... | {
"pile_set_name": "PubMed Abstracts"
} |
Dietary Iron Modulates Glucose and Lipid Homeostasis in Diabetic Mice.
Imbalance of iron homeostasis has been involved in clinical courses of metabolic diseases such as type 2 diabetes mellitus, obesity, and nonalcoholic fatty liver, through mechanisms not yet fully elucidated. Herein, we evaluated the effect of dietar... | {
"pile_set_name": "PubMed Abstracts"
} |
[Rare cases of prostatitis caused by invasion of Trichomonas vaginalis with Candida albicans].
Three cases of prostatitis caused by the invasion of T. vaginalis and C. albicans which has been found in different biological materials were described. After per rectum examination perineum biopsy of prostata was performed i... | {
"pile_set_name": "PubMed Abstracts"
} |
Computerised tomography localisation of intrarenal calculi prior to nephrolithotomy.
The use of the EMI CT 5005 scanner in patients with renal calculus disease is described. This investigation was found to be a useful aid in the accurate localisation of calculi within the renal collecting system prior to surgery. | {
"pile_set_name": "PubMed Abstracts"
} |
Duration of homologous porcine reproductive and respiratory syndrome virus immunity in pregnant swine.
The duration of porcine reproductive and respiratory syndrome virus (PRRSV) homologous immunity was tested in this study and found to last for at least 604 days post experimental exposure to field PRRSV. Eleven gilts ... | {
"pile_set_name": "PubMed Abstracts"
} |
Nuclear import of cellular retinoic acid-binding protein type I in mouse embryonic cells.
Using confocal microscopy we show that cellular retinoic acid-binding protein type I (CRABP I), expressed in several embryonic cell types, displays a compartmentalized subcellular distribution. The protein was excluded from the nu... | {
"pile_set_name": "PubMed Abstracts"
} |
Collective oscillations in the classical nonlinear response of a chaotic system.
We establish a general semiquantitative phase-space picture of the classical nonlinear response in a strongly chaotic system. As opposed to the case of stable dynamics, the response functions decay exponentially at long times. Damped oscil... | {
"pile_set_name": "PubMed Abstracts"
} |
Effect of diet restriction on some biochemical parameters related to aging in mice.
The effects of chronic diet restriction in mice on some biochemical parameters related to aging have been investigated. Restriction of food intake to about one-half of the ad libitum consumption resulted in a significantly decreased gro... | {
"pile_set_name": "PubMed Abstracts"
} |
[Evidence-based pharmacotherapy and other somatic treatment approaches for obsessive-compulsive disorder: state of the art].
Meta-analyses of the randomized controlled trials (RCT) in obsessive-compulsive disorder (OCD) have clearly demonstrated that selective serotonin reuptake inhibitors (SSRIs) are the medication tr... | {
"pile_set_name": "PubMed Abstracts"
} |
Abdominal wall hernia repair in cirrhotic patients: outcomes seen at a tertiary care hospital in a developing country.
The outcome of hernia repair in patients with cirrhosis remains poor when compared to non-cirrhotics. The aim of our study was to evaluate the outcome of hernia repair in cirrhotic patients at our tert... | {
"pile_set_name": "PubMed Abstracts"
} |
Is medically assisted death a special obligation?
Several distinct arguments conclude that terminally ill patients have a right to a medically assisted death; two are especially influential: the autonomy argument and the non-harm argument. Both have proven convincing to many, but not to those who view the duty not to k... | {
"pile_set_name": "PubMed Abstracts"
} |
[Spanish study of quality of life in migraine (I). Profile of the patient with migraine attending neurology clinics].
Migraine is the main reason for neurological consultation. To analyse the profile of the patient with migraine attending the Neurological Services of our country. Neurologists from 7 hospitals in differ... | {
"pile_set_name": "PubMed Abstracts"
} |
Local therapy of corneal allograft rejection with cyclosporine.
We evaluated the therapeutic effect of 0.5% topical cyclosporine on human corneal allograft rejection. Sixteen patients (16 eyes) with corneal allograft rejection, refractory to the conventional treatments, were recruited and treated with 0.5% cyclosporine... | {
"pile_set_name": "PubMed Abstracts"
} |
Purification, crystallization, and preliminary x-ray diffraction studies of the flavoenzyme mercuric ion reductase from Bacillus sp. strain RC607.
The flavoenzyme mercuric ion reductase from Bacillus sp. strain RC607 was purified by dye-ligand affinity chromatography. The protein was crystallized from solutions of high... | {
"pile_set_name": "PubMed Abstracts"
} |
Radiation-induced bilateral coronary ostial stenosis in a 17-year-old patient.
Mediastinal irradiation can induce coronary artery disease characterized by the localization of lesions at the proximal segment of the arteries. We report the case of a 17-year-old patient who underwent a mediastinal irradiation for pulmonar... | {
"pile_set_name": "PubMed Abstracts"
} |
Mycoplasma genitalium, a stealth female reproductive tract.
Mycoplasma genitalium was first isolated from the urethral swabs of two symptomatic men with urethritis in 1980. It is a sexually transmitted bacterium associated with a number of urogenital conditions in women like cervicitis, endometritis, pelvic inflammator... | {
"pile_set_name": "PubMed Abstracts"
} |
The Lewis-Y carbohydrate antigen is expressed by many human tumors and can serve as a target for genetically redirected T cells despite the presence of soluble antigen in serum.
In this study we aimed to determine the suitability of the Lewis-Y carbohydrate antigen as a target for immunotherapy using genetically redire... | {
"pile_set_name": "PubMed Abstracts"
} |
Familial fatal fetal cardiomyopathy with isolated myocardial calcifications: a new syndrome?
We describe three male sib fetuses with isolated myocardial calcifications resulting in intrauterine fetal death (IUFD) as early as the second trimester. No evidence for an underlying mitochondrial cytopathy, dystrophinopathy o... | {
"pile_set_name": "PubMed Abstracts"
} |
[Stent graft for rapidly growing thoracic mycotic aneurysm in a patient with advanced lung cancer].
We report a compromised patient with mycotic aneurysm, who was successfully treated by urgent placement of a stent graft. A man in his seventies was admitted to our hospital with relapsing high fever and back pain during... | {
"pile_set_name": "PubMed Abstracts"
} |
[Intertrochanteric flexion osteotomy in aseptic osteonecrosis of the femoral head in adults. Apropos of 52 cases].
Fifty-two intertrochanteric osteotomies were performed in 42 cases of idiopathic avascular necrosis of the femoral head of which 10 were bilateral. By flexion at the osteotomy site, the operation aims to p... | {
"pile_set_name": "PubMed Abstracts"
} |
[Roles of p53 in chemotherapy of glioblastoma].
LN382, a glioblastoma cell line, has a temperature-sensitive mutant p53. At the permissive temperature (34 degrees C), arrest of cell growth at the G1 phase occurred with recovered p53's transcriptional activity, and restored p53 protein turnover. In order to understand t... | {
"pile_set_name": "PubMed Abstracts"
} |
Computed tomography of intracranial lymphoma.
The appearances on computed tomography (CT) of 17 patients with histologically proven intracranial lymphoma have been analysed and abnormalities detected in 16. Four of the patients had systemic lymphoma. Multiple lesions were seen in eight patients (47%), in six of whom th... | {
"pile_set_name": "PubMed Abstracts"
} |
Formation of ascochitine by plant pathogens of the genus Ascochyta.
Strains of fungi isolated from pulse crops: pea (Pisum sativum) and faba beans (Vicia faba) plants with symptoms of Ascochyta blight, footrot and stems lesions have been examined under laboratory conditions for their ability to produce ascochitine and ... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of fixation method on image cytometric measurement of DNA content and distribution in cells stained for fluorescence with propidium iodide.
We performed image cytometric measurements of DNA content and distribution on cycling human HCT-8 cells stained for fluorescence with propidium iodide (PI). Seven different... | {
"pile_set_name": "PubMed Abstracts"
} |
Experimental observations of the threshold-like onset of mode instabilities in high power fiber amplifiers.
We report on the observation and experimental characterization of a threshold-like onset of mode instabilities, i.e. an apparently random relative power content change of different transverse modes, occurring in ... | {
"pile_set_name": "PubMed Abstracts"
} |
True histiocytic lymphoma with multiple skin nodules.
A 73-year-old white woman developed multiple cutaneous nodules that fluctuated in size and occasionally regressed. The tumor cells infiltrating the dermis were histiocytic by light microscopy, marker studies, and electron microscopy. Similar cells were present in a ... | {
"pile_set_name": "PubMed Abstracts"
} |
Transport of pyruvate by luminal membrane vesicles from pars convoluta and pars recta of rabbit proximal tubule.
The characteristics of renal transport of pyruvate by luminal membrane vesicles from pars convoluta and pars recta of rabbit proximal tubule were studied. It was found that the uptake of pyruvate in these ve... | {
"pile_set_name": "PubMed Abstracts"
} |
Mutagenicity of expectorate from workers in a coke plant.
Methanol extracts of hydrolyzed expectorate samples from workers in a coke plant were tested with the Salmonella reversion assay. The expectorates from exposed smokers (but also to a certain extent from exposed non-smokers) were mutagenic; however, the control s... | {
"pile_set_name": "PubMed Abstracts"
} |
Martian dust storm impact on atmospheric H2O and D/H observed by ExoMars Trace Gas Orbiter.
Global dust storms on Mars are rare1,2 but can affect the Martian atmosphere for several months. They can cause changes in atmospheric dynamics and inflation of the atmosphere3, primarily owing to solar heating of the dust3. In ... | {
"pile_set_name": "PubMed Abstracts"
} |
[A case of membranous nephropathy with ANCA-associated necrotizing glomerulonephritis during oral administration of PTU for Graves' disease].
We experienced a coincidental case of two types of glomerulopathy associated with Graves' disease. A 64-year-old man, who had been treated with propylthiouracil(PTU) for Graves' ... | {
"pile_set_name": "PubMed Abstracts"
} |
[The antihypertensive activity of benazepril in the long-term treatment of hypertension patients and its effect on adrenal cortical function].
Changes in arterial hypertension, heart rate and adrenocortical hormones (11-OCS, aldosteron, progestins) in the blood and 24-h urine were followed up in the course of 24-week u... | {
"pile_set_name": "PubMed Abstracts"
} |
Use of complexing agents for effective ion-exchange separation of Co(II)/Ni(II) from aqueous solutions.
Cation-exchange separation of Co(2+)/Ni(2+) from aqueous solutions using water-soluble complexing agents of ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid (NTA), iminodiacetic acid (IDA), and citrate w... | {
"pile_set_name": "PubMed Abstracts"
} |
Caspase-3 is involved in IFN-γ- and TNF-α-mediated MIN6 cells apoptosis via NF-κB/Bcl-2 pathway.
TNF-α and IFN-γ are the major pro-inflammatory cytokines in the β-cell destruction. However, the underlying mechanism remains unclear. The present study used a murine insulinoma cell line MIN6 for further investigation of t... | {
"pile_set_name": "PubMed Abstracts"
} |
Determination of ester carbonyl 18O/16O ratios in phospholipids by gas chromatography-mass spectrometry.
A method is described for the quantitation of 18O enrichment in phospholipid acyl groups. Methyl esters are prepared by transesterification with sodium hydroxide in methanol and are hydrogenated prior to gas chromat... | {
"pile_set_name": "PubMed Abstracts"
} |
Microcrystalline Zinc Coordination Polymers as Single-site Heterogeneous Catalysts for the Selective Synthesis of Mono-oxazolines from Amino Alcohol and Dinitriles.
In our effort to develop coordination polymers (CPs)-based single-site catalysts for the selective synthesis of mono-oxazolines, two Zn-based CPs, [{Zn6 (i... | {
"pile_set_name": "PubMed Abstracts"
} |
Fabrication of novel magnetic graphene oxide nanocomposites for selective adsorption of mercury from aqueous solutions.
In this work, a novel functionalized graphene oxide (GO) was used as an effective and selective adsorbent for removal of mercury (Hg2+). The magnetic nanocomposite adsorbent (MNA) based on GO was prep... | {
"pile_set_name": "PubMed Abstracts"
} |
Computational insights into the molecular interactions of environmental xenoestrogens 4-tert-octylphenol, 4-nonylphenol, bisphenol A (BPA), and BPA metabolite, 4-methyl-2, 4-bis (4-hydroxyphenyl) pent-1-ene (MBP) with human sex hormone-binding globulin.
Environmental contamination has been one of the major drawbacks of... | {
"pile_set_name": "PubMed Abstracts"
} |
INCAP studies of vegetable proteins for human consumption.
This article describes the efforts of the Institute of Nutrition of Central America and Panama (INCAP) to develop a relatively low-cost vegetable protein mixture suitable as a complementary food for infants and young children. As it turned out, the resulting pr... | {
"pile_set_name": "PubMed Abstracts"
} |
Neonatal exposure to methyl chloroform in tape remover.
Methyl chloroform (MC) is commonly used solvent found in some adhesive tape remover products used in intensive care nurseries. Since volatile substances can accumulate inside an infant incubator, we measured levels of MC following simulated use of 2 commercially a... | {
"pile_set_name": "PubMed Abstracts"
} |
FZD8, a target of p53, promotes bone metastasis in prostate cancer by activating canonical Wnt/β-catenin signaling.
Prostate cancer (PCa) is the second most frequently diagnosed cancer among men and exhibits a high propensity to metastasize to bone. Currently, bone metastasis remains incurable, and therapies are limite... | {
"pile_set_name": "PubMed Abstracts"
} |
Protein kinase C pathway potentiates androgen-mediated gene expression of the mouse vas deferens specific aldose reductase-like protein (MVDP).
Transcription of the mouse vas deferens protein (MVDP) gene, a member of the aldo-keto reductase superfamily, is stimulated by androgens via the androgen responsive element (AR... | {
"pile_set_name": "PubMed Abstracts"
} |
A comparative study of two antimicrobial/anti-inflammatory formulations in the treatment of canine otitis externa.
The efficacy and tolerability of a marbofloxacin-clotrimazole-dexamethasone otic suspension (MCD) was compared with a standard topical treatment using a phase III clinical trial protocol. In a total of 140... | {
"pile_set_name": "PubMed Abstracts"
} |
Video-assisted thoracic surgery for fibropurulent thoracic empyema: a bridge to open thoracic surgery.
Thoracic empyema remains a serious problem. We evaluated the feasibility and efficacy of video-assisted thoracic surgery (VATS) for fibropurulent thoracic empyema. Twenty-six consecutive patients with thoracic empyema... | {
"pile_set_name": "PubMed Abstracts"
} |
Synthesis and structures of Co bis-trifluoromethylpyrazolate complexes.
Reactions of Co(PMe3)3Cl or CoCl2 with 3,5-(CF3)2-PzNa in hexane give Co(PMe3)3(3,5-(CF3)2-Pz) (1) and Co(PMe3)3(3,5-(CF3)2-Pz)2 (2) respectively (3,5-(CF3)2-PzNa = sodium bis-trifluoromethylpyrazolate). Reaction of (3,5-(CF3)2-PzH) with Co(PMe3)4 ... | {
"pile_set_name": "PubMed Abstracts"
} |
Development and validation of an arthropod maceration protocol for zoonotic pathogen detection in mosquitoes and fleas.
Arthropod-borne diseases remain a pressing international public health concern. While progress has been made in the rapid detection of arthropod-borne pathogens via quantitative real-time (qPCR), or e... | {
"pile_set_name": "PubMed Abstracts"
} |
Serial decline of kidney function as a novel biomarker for the progression of atherothrombotic disease.
Impaired kidney function is associated with cardiovascular disease. However, from the available data it cannot be discerned which of the two entities presents first and entails the other. If renal dysfunction is firs... | {
"pile_set_name": "PubMed Abstracts"
} |
Sunspots and the recency theory of schizophrenia.
Schizophrenia, a disorder with a high, fairly uniform, global distribution, can occur with or without an accompanying family history of mental disorder. Given the preponderance of sporadic cases and the low fertility of genetic cases, this combination suggests that the ... | {
"pile_set_name": "PubMed Abstracts"
} |
Four disruptive strategies for removing drug discovery bottlenecks.
Drug discovery is shifting focus from industry to outside partners and, in the process, creating new bottlenecks. Technologies like high throughput screening (HTS) have moved to a larger number of academic and institutional laboratories in the USA, wit... | {
"pile_set_name": "PubMed Abstracts"
} |
Opioid and Cannabis Co-Use among Adults With Chronic Pain: Relations to Substance Misuse, Mental Health, and Pain Experience.
Opioid misuse constitutes a significant public health problem and is associated with a host of negative outcomes. Despite efforts to curb this increasing epidemic, opioids remain the most widely... | {
"pile_set_name": "PubMed Abstracts"
} |
Difference in the dynamic properties of chiral and racemic crystals of serine studied by Raman spectroscopy at 3-295 K.
Single-crystal polarized Raman spectra (60-4000 cm(-1) at 3 < or = T < or = 295 K) were measured for chiral L- and racemic DL-serine, alpha-amino-beta-hydroxypropionic acid, (NH3)+CH(CH2OH)(COO)-. The... | {
"pile_set_name": "PubMed Abstracts"
} |
BAY 11-7082, a nuclear factor-κB inhibitor, reduces inflammation and apoptosis in a rat cardiac ischemia-reperfusion injury model.
Despite development of therapeutic modalities, myocardial ischemia-reperfusion (I/R) injury remains an important cause of cardiac dysfunction. Multiple strategies exist experimentally, but ... | {
"pile_set_name": "PubMed Abstracts"
} |
MERTK polymorphisms associated with risk of haematological disorders among Korean SLE patients.
The MER receptor tyrosine kinase (MERTK) gene is critical for the efficient clearance of apoptotic cells and has implications for inflammation and autoimmune diseases such as systemic lupus erythematosus (SLE). We investigat... | {
"pile_set_name": "PubMed Abstracts"
} |
Neurobiological substrates of antisocial and borderline personality disorder: preliminary results of a functional fMRI study.
Neuropsychological and imaging studies of patients with antisocial (ASPD) and borderline personality disorder (BPD) are suggestive of frontal lobe dysfunction in these individuals. In normal sub... | {
"pile_set_name": "PubMed Abstracts"
} |
The role of miR-17-92 cluster in the expression of tumor suppressor genes in unrestricted somatic stem cells.
The miR-17-92 cluster consisted of seven miRNAs (mir-17-5p, -17-3p, -18a, -19a, -20a, -19b-1, and -92a-1). Previous studies have shown this cluster has been over-expressed in several cancers. The aim of this st... | {
"pile_set_name": "PubMed Abstracts"
} |
Role of climate in the spread of shiga toxin-producing Escherichia coli infection among children.
Haemolytic-uraemic syndrome (HUS) is a rare disease mainly affecting children that develops as a complication of shiga toxin-producing Escherichia coli (STEC) infection. It is characterised by acute kidney injury, platelet... | {
"pile_set_name": "PubMed Abstracts"
} |
A long-term study of doxazosin in the treatment of mild or moderate essential hypertension in general medical practice.
This study assessed the long-term (54 weeks) antihypertensive efficacy and safety of doxazosin in the treatment of mild or moderate essential hypertension, defined as sitting and standing diastolic bl... | {
"pile_set_name": "PubMed Abstracts"
} |
Nondestructive optical measurements of a single electron spin in a quantum dot.
Kerr rotation measurements on a single electron spin confined in a charge-tunable semiconductor quantum dot demonstrate a means to directly probe the spin off-resonance, thus minimally disturbing the system. Energy-resolved magneto-optical ... | {
"pile_set_name": "PubMed Abstracts"
} |
[Uncertain if physicians' shift work causes patient harm].
The role of physicians' shift work in adverse events causing patient harm is not clear. However, extended shifts reduce psychomotor performance and cognition in daytime after a 24-hour shift. The incidence and preventability of adverse events in Denmark are com... | {
"pile_set_name": "PubMed Abstracts"
} |
Reverse perfusion-metabolism mismatch predicts good prognosis in patients undergoing cardiac resynchronization therapy: a pilot study.
Cardiac resynchronization therapy (CRT) improves glucose metabolism in the septum of patients with heart failure, so in the present study the predictive value of combined fluorodeoxyglu... | {
"pile_set_name": "PubMed Abstracts"
} |
Subtrochanteric fractures of the femur.
A consecutive series of 103 patients with a subtrochanteric fracture were prospectively studied. Ten patients were treated non-operatively, whilst the other 93 had operative treatment. The overall fixation failure rate was 12 per cent with a re-operation rate of 6 per cent by 1 y... | {
"pile_set_name": "PubMed Abstracts"
} |
Investigation of excipient and processing on solid phase transformation and dissolution of ciprofloxacin.
Ciprofloxacin, a very slightly soluble antibiotics, is known to exist as both anhydrous and hydrous forms. This study was carried out to investigate the solid phase transformation of ciprofloxacin during convention... | {
"pile_set_name": "PubMed Abstracts"
} |
Mibefradil, a T-type Ca2+ channel blocker, protects against mesenteric ischemia-reperfusion-induced oxidative injury and histologic alterations in intestinal mucosa in rats.
The purpose of the present study was to investigate whether mibefradil can reduce oxidative stress and histologic damage in the rat small bowel su... | {
"pile_set_name": "PubMed Abstracts"
} |
Negative synergism of rainfall patterns and predators affects frog egg survival.
1. The importance of rainfall is recognized in arid habitats, but has rarely been explored in ecosystems not viewed as rainfall limited. In addition, most attempts to study how rainfall affects organismal survival have focused on long-term... | {
"pile_set_name": "PubMed Abstracts"
} |
Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats.
Diabetes is associated with an increased risk of fracture, although type 2 diabetes is often characterized by normal bone mineral density (BMD). Enzymatic and glycation-induced non-enzym... | {
"pile_set_name": "PubMed Abstracts"
} |
TB Alliance regimen development for multidrug-resistant tuberculosis.
The recent approval of new tuberculosis (TB) drugs raises hope for new and more effective anti-tuberculosis treatment regimens. The Global Alliance for TB Drug Development (TB Alliance) is committed to ensuring that new anti-tuberculosis drugs fulfil... | {
"pile_set_name": "PubMed Abstracts"
} |
Rational theophylline use in older asthmatics.
In the sick adult, the variability of clearance from patient to patient may be greater than 50%. A given dose of theophylline that is predicted to result in a serum concentration of 15 micrograms/ml may result in an actual range of serum concentrations from 6.6 to 33 micro... | {
"pile_set_name": "PubMed Abstracts"
} |
Interference of xenoestrogen o,p'-DDT on the action of endogenous estrogens at environmentally realistic concentrations.
Estrogenic effects of individual chemicals and mixtures of 17β-estradiol (E2) and o,p'-DDT were examined using pS2 and PR gene expressions in MCF-7 cells. Interactions between E2 and o,p'-DDT were ev... | {
"pile_set_name": "PubMed Abstracts"
} |
Effects of the capsaicin analogue resiniferatoxin on spinal nociceptive mechanisms in the rat: behavioral, electrophysiological and in situ hybridization studies.
The effect of a single subcutaneous (s.c.) injection of the ultrapotent capsaicin analogue resiniferatoxin (RTX) on responses of adult rats to noxious therma... | {
"pile_set_name": "PubMed Abstracts"
} |
Wafer-Scale and Wrinkle-Free Epitaxial Growth of Single-Orientated Multilayer Hexagonal Boron Nitride on Sapphire.
Large-scale growth of high-quality hexagonal boron nitride has been a challenge in two-dimensional-material-based electronics. Herein, we present wafer-scale and wrinkle-free epitaxial growth of multilayer... | {
"pile_set_name": "PubMed Abstracts"
} |
Small-molecule fluorophores and fluorescent probes for bioimaging.
Fluorescent compounds based on synthetic small molecules are powerful tools to visualize biological events in living cells and organisms. Ever since the discovery of organic fluorescent compounds in the late nineteenth century, efforts have been made to... | {
"pile_set_name": "PubMed Abstracts"
} |
The tragedy of Tauccamarca: a human rights perspective on the pesticide poisoning deaths of 4 children in the Peruvian Andes.
The pesticide poisoning deaths of 24 children in an isolated Peruvian village make a compelling case that corporate accountability for pesticide poisonings in the developing south should be exam... | {
"pile_set_name": "PubMed Abstracts"
} |
Water and methanolic extracts of Salvia officinalis protect HepG2 cells from t-BHP induced oxidative damage.
Common sage (Salvia officinalis L., Lamiaceae) is an aromatic and medicinal plant well known for its antioxidant properties. Some in vivo studies have shown the biological antioxidant effects of sage. However, t... | {
"pile_set_name": "PubMed Abstracts"
} |
[The initial stage of disease].
The many-year experience of comparing the clinical picture of human disease with its pathological picture indicates that man begins to be aware of the pathological process typical of a given disease in many cases after some, not infrequently long period after its initiation and against t... | {
"pile_set_name": "PubMed Abstracts"
} |
Influence of tertiary structure domain properties on the functionality of apolipoprotein A-I.
The tertiary structure of apolipoprotein (apo) A-I and the contributions of structural domains to the properties of the protein molecule are not well defined. We used a series of engineered human and mouse apoA-I molecules in ... | {
"pile_set_name": "PubMed Abstracts"
} |
Early detection of damage to nerves in leprosy.
Methods of examining and diagnosing damage to nerves commonly involved in leprosy are described. The equipment used is inexpensive, gives reliable and repeatable results and is useful in making objective assessments in terms of function in everyday living. | {
"pile_set_name": "PubMed Abstracts"
} |
Methodologies for the care, maintenance, and breeding of tropical poison frogs.
The Biodiversity Laboratories at Saint Joseph's University house more than 100 exotic and endangered animal species-including insects, fish, amphibians, and reptiles. Research in the laboratories is devoted, primarily, to understanding the ... | {
"pile_set_name": "PubMed Abstracts"
} |
Evaluation of a protease assay based on a natural protein for heavy metals inhibition of activated sludge.
An enzymatic assay employing 2,4,6-trinitrobenzenesulfonic acid to follow the hydrolysis reaction of peptide bonds of a natural protein by activated sludge was evaluated for assessing the inhibition caused by heav... | {
"pile_set_name": "PubMed Abstracts"
} |
Two cases with severe lethal course of Costello syndrome associated with HRAS p.G12C and p.G12D.
Costello syndrome (CS) is a rare congenital disorder characterized by severe failure to thrive, coarse facial appearance, cardiac and skin abnormalities, developmental delay, intellectual disability, and predisposition to m... | {
"pile_set_name": "PubMed Abstracts"
} |
The impact of three-dimensional tumor volume on cancer-specific survival for patients with pT1 clear-cell renal cell carcinoma.
To evaluate the impact of three-dimensional tumor volume on cancer-specific survival for patients with pT1 clear-cell renal cell carcinoma (ccRCC). We reviewed a prospectively maintained datab... | {
"pile_set_name": "PubMed Abstracts"
} |
An operative repair of acromioclavicular separation.
Sixteen patients underwent an open reduction for complete acromioclavicular separation with a loop of woven Dacron arterial graft. This technique of internal fixation permits an early range of shoulder motion and eliminates the need for a second procedure to remove w... | {
"pile_set_name": "PubMed Abstracts"
} |
Ultrastructural morphology of the olfactory pathway for cerebrospinal fluid drainage in the rabbit.
Previous physiological studies indicate that the olfactory region serves as a major pathway for cerebrospinal fluid (CSF) drainage into the lymphatic system. The present study was undertaken to determine the ultrastructu... | {
"pile_set_name": "PubMed Abstracts"
} |
Difficult clinical challenges in haemophilia: international experiential perspectives.
Haemostasis management in people with haemophilia can present a range of challenges to physicians. Specific challenges that may be encountered relate to regimens for immune tolerance induction, use of central venous access devices, o... | {
"pile_set_name": "PubMed Abstracts"
} |
[The role of host cells in the genetic regulation of plasmid transfer in Escherichia coli].
The role of serologically typed and nontyped E. coli cells in the expression of genetic regulation systems activity for repressed plasmids transfer (types fin OP, fin U, fin V) was studied. It is shown that the inhibiting action... | {
"pile_set_name": "PubMed Abstracts"
} |
Intrauterine devices: present and future.
Although the mortality associated with the use of intrauterine contraception is low, its morbidity is probably higher than that associated with oral contraception. Much anxiety has been generated and whole programs prejudiced by lack of attention to detail during counseling, th... | {
"pile_set_name": "PubMed Abstracts"
} |
K-CL co-transport plays an important role in normal and beta thalassemic erythropoiesis.
Cell volume changes are hallmarks of both cell maturation and apoptosis, and are paralleled by modulation of membrane ion transport pathways. We evaluated the possible role of K-Cl co-transport (KCC) in both normal and beta-thalass... | {
"pile_set_name": "PubMed Abstracts"
} |
High-resolution mapping of the optical near-field components at a triangular nano-aperture.
A triangular nano-aperture in an aluminum film was used as a probe in a scanning near-field optical microscope (SNOM) to image single fluorescent molecules with an optical resolution down to 30 nm. The differently oriented molec... | {
"pile_set_name": "PubMed Abstracts"
} |
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