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Computational simulation of spontaneous bone straightening in growing children. Periosteal surface pressures have been shown to inhibit bone formation and induce bone resorption, while tensile strains perpendicular to the periosteal surface have been shown to inhibit bone resorption and induce new bone deposition. A ne...
{ "pile_set_name": "PubMed Abstracts" }
Vinyl-vinyl coupling on late transition metals through C-C reductive elimination mechanism. A computational study. A detailed density functional study was performed for the vinyl-vinyl reductive elimination reaction from bis-sigma-vinyl complexes [M(CH=CH(2))(2)X(n)]. It was shown that the activity of these complexes d...
{ "pile_set_name": "PubMed Abstracts" }
Chasing the genes that control resistance to gastrointestinal nematodes. The host-protective immune response to infection with gastrointestinal (GI) nematodes involves a range of interacting processes that begin with recognition of the parasite's antigens and culminate in an inflammatory reaction in the intestinal muco...
{ "pile_set_name": "PubMed Abstracts" }
Mobile iron nanoparticle and its role in the formation of SiO2 nanotrench via carbon nanotube-guided carbothermal reduction. The detailed role of iron nanoparticles (NPs) involved with the formation of SiO2 nanotrenches is revealed. The physical movements of iron NPs, such as levitation and adsorption, turn out to be r...
{ "pile_set_name": "PubMed Abstracts" }
Differential effects of post-implantation time on potassium- versus D-amphetamine-evoked dopamine overflow in the striatum of F344 rats. Effects of post-implantation time on potassium (K+)- versus D-amphetamine (D-AMPH)-evoked striatal dopamine (DA) overflow were measured using microdialysis in freely moving young and ...
{ "pile_set_name": "PubMed Abstracts" }
An aptasensor for detection of potassium ions based on RecJ(f) exonuclease mediated signal amplification. An electrochemical biosensor for potassium has been developed combining specific potassium-aptamer binding and RecJf exonuclease mediated signal amplification. Generally, the DNA probe with a stem-loop structure co...
{ "pile_set_name": "PubMed Abstracts" }
Analysis of foraminifera assemblages and sediment geochemical properties to characterise the environment near Araçá and Saco da Capela domestic sewage submarine outfalls of São Sebastião Channel, São Paulo State, Brazil. Superficial bottom samples were collected near diffusers of domestic sewage submarine outfalls at A...
{ "pile_set_name": "PubMed Abstracts" }
New strip immunoblot for the confirmation of HTLV-I/II infection. In The Netherlands, anti-human T-cell lymphotropic virus type I (HTLV-I) blood donor screening became mandatory in January 1993. Donations reactive in the enzymelinked immunosorbent assay (ELISA) screening test are confirmed with Western blot analysis (W...
{ "pile_set_name": "PubMed Abstracts" }
Application of Alu-splice PCR on chromosome 21: DSCR1 and Intersectin. Down syndrome (DS) is a major cause of mental retardation and congenital heart defects, with an overall incidence of one in 700 live births. DS is caused by increases in the amounts of a number of normal gene products, the exact number and identity ...
{ "pile_set_name": "PubMed Abstracts" }
Endobronchial tuberculosis presenting as tumorous mass. We report a case of an 18-year-old boy presenting with features of right middle lobe collapse. On bronchoscopy, a tumorous type of endobronchial tuberculosis was found to be obstructing the lumen of the right middle lobe bronchus. On treatment with anti-tuberculou...
{ "pile_set_name": "PubMed Abstracts" }
[Adult human retinal pigment epithelial cells - a potential source of cells for regeneration retina]. Retinal pigment epithelium (RPE) arises from neuroectoderm and plays a key role in support of photoreceptor functions. Several degenerative eye diseases, such as macular degeneration or retinitis pigmentosa, are associ...
{ "pile_set_name": "PubMed Abstracts" }
Rate of false source attributions depends on how questions are asked. Lindsay and Johnson (1989) and Zaragoza and Koshmider (1989) report evidence indicating that "eyewitness" subjects are much less likely to falsely claim to have seen information suggested to them verbally when they receive a source monitoring test th...
{ "pile_set_name": "PubMed Abstracts" }
Mineralocorticoid excess and inhibition of 11 beta-hydroxysteroid dehydrogenase in patients with ectopic ACTH syndrome. 11 beta-Hydroxysteroid dehydrogenase protects renal mineralocorticoid receptors from cortisol by converting cortisol to inactive cortisone. We hypothesize that 11 beta-dehydrogenase is inhibited by AC...
{ "pile_set_name": "PubMed Abstracts" }
Short- and long-term functional alterations of the skeletal muscle calcium release channel (Ryanodine receptor) by Suramin: apparent dissociation of single channel current recording and [3H]ryanodine binding. The present study demonstrates the following characteristic suramin actions on the purified skeletal muscle cal...
{ "pile_set_name": "PubMed Abstracts" }
Nasal obstruction following septorhinoplasty: how well does acoustic rhinometry work? Septorhinoplasty aims to improve not only the esthetic appearance but also breathing function of the nose. Although the esthetic improvement can be judged by the patient and the surgeon easily, evaluation of nasal breathing is more co...
{ "pile_set_name": "PubMed Abstracts" }
Heterogeneous effect of an Emergency Department Expert Charting System. We compare results from different modules (occupational exposure to blood and body fluids, low back pain, and fever in children) of the Emergency Department Expert Charting System. Each module of this electronic medical record provides real-time ad...
{ "pile_set_name": "PubMed Abstracts" }
[Parkinson disease : how to improve the voice and the quality of life]. Parkinson disease is a progressive neurodegenerative disease affecting the basal ganglia and causing the degeneration of dopaminergic neurons. It is a chronic affection with a slow evolution characterized by motor dysfunctions. Considering voice an...
{ "pile_set_name": "PubMed Abstracts" }
Rotator cuff regeneration using a bioabsorbable material with bone marrow-derived mesenchymal stem cells in a rabbit model. Rotator cuff regeneration using tissue engineering techniques is a challenging treatment in elderly patients with irreparable rotator cuff tears. A polyglycolic acid sheet scaffold with seeded mes...
{ "pile_set_name": "PubMed Abstracts" }
Feline bone marrow transplantation: its use in FIV-infected cats. The use of autologous and allogenic bone marrow transplantations (BMT) in FIV-infected and uninfected cats is a novel therapy for feline hematopoietic diseases and retroviral infections. A total of 13 specific pathogen-free (SPF) cats received either aut...
{ "pile_set_name": "PubMed Abstracts" }
A comparative joint simulator study of the wear of metal-on-metal and alternative material combinations in hip replacements. While total hip replacement represents the major success story in orthopaedic surgery in the twentieth century, there is much interest in extending even further, early in the twenty first century...
{ "pile_set_name": "PubMed Abstracts" }
Next generation prophylactic human papillomavirus vaccines. The two licensed bivalent and quadrivalent human papillomavirus (HPV) L1 (the major papillomavirus virion protein) virus-like particle (VLP) vaccines are regarded as safe, effective, and well established prophylactic vaccines. However, they have some inherent ...
{ "pile_set_name": "PubMed Abstracts" }
Nursing Home Physicians' Assessments of Barriers and Strategies for End-of-Life Care in Norway and The Netherlands. Working conditions in nursing homes (NHs) may hamper teamwork in providing quality end-of-life (EOL) care, especially the participation of NH physicians. Dutch NH physicians are specialists or trainees in...
{ "pile_set_name": "PubMed Abstracts" }
Association between antennal phenotype, wing polymorphism and sex in the genus Mepraia (Reduviidae: Triatominae). Mepraia spinolai and Mepraia gajardoi (Hemiptera, Reduviidae) are only found in the arid regions of northern Chile. Mepraia is the only genus of Triatominae with marked wing polymorphism. Females of both sp...
{ "pile_set_name": "PubMed Abstracts" }
Speed cameras in Sweden and Victoria, Australia--a case study. In this article, the ideas behind two different speed camera systems in Australia, Victoria, and Sweden are explored and compared. The study shows that even if the both systems technically have the same aim--to reduce speeding--the ideas of how that should ...
{ "pile_set_name": "PubMed Abstracts" }
Total synthesis of antofine using the net [5+5]-cycloaddition of gamma,delta-unsaturated carbene complexes and 2-alkynylphenyl ketones as a key step. A compound containing all of the carbons of the anticancer agent antofine was produced in a single step from the coupling of a gamma,delta-unsaturated carbene complex wit...
{ "pile_set_name": "PubMed Abstracts" }
Na,K-ATPase receptor subunits alpha 1, alpha 2 and alpha 3 mRNA in dilated cardiomyopathy. Na,K-ATPase receptor density has been shown to be down-regulated with decreasing ejection fraction in patients with chronic heart failure. It was the aim of the present study to determine whether down-regulation is detected also ...
{ "pile_set_name": "PubMed Abstracts" }
Systemic collateral and pulmonary artery stenosis in patients with congenital pulmonary valve atresia and ventricular septal defect. Angiograms of 30 patients with congenital pulmonary valve atresia, ventricular septal defect, and large systemic-pulmonary collateral arteries (SPCAs) were evaluated. All had aortography,...
{ "pile_set_name": "PubMed Abstracts" }
Macrophage colony-stimulating factor accelerates wound healing and upregulates TGF-beta1 mRNA levels through tissue macrophages. Macrophage colony-stimulating factor (M-CSF) is produced by many cell types involved in wound repair, yet it acts specifically on monocytes and macrophages. The monocyte-derived cell is thoug...
{ "pile_set_name": "PubMed Abstracts" }
M-PEIs nanogels: potential nonviral vector for systemic plasmid delivery to tumor cells. Successfully systemic gene therapy has been hindered by vector-related limitations, including toxicity and inefficient gene delivery to tumor cells after intravenous administration. In this study, we evaluated the potential of sphe...
{ "pile_set_name": "PubMed Abstracts" }
Methods for implanting steroid-containing cannulae into the paraventricular nucleus of neonatal rats. Implantation of cannulae into brains of neonatal rats presents methodological difficulties. We discuss such issues as avoiding tissue injury, and describe successful techniques. Cannulae size, methods of preparation, i...
{ "pile_set_name": "PubMed Abstracts" }
Emotional response to the ano-genital examination of suspected sexual abuse. Concerns have arisen among professionals working with children regarding potential emotional distress as a result of the ano-genital examination for suspected child sexual abuse. The purpose of this study was to describe and compare children's...
{ "pile_set_name": "PubMed Abstracts" }
Causes and therapy of microinflammation in renal failure. Microinflammation in renal failure has been the subject of numerous studies, but the causes of the inflammatory response in these patients are not clear. There are several potential causes and possible therapies for microinflammation, and they are discussed in t...
{ "pile_set_name": "PubMed Abstracts" }
How have people who have stopped or reduced their alcohol consumption incorporated this into their social rituals? Limiting alcohol consumption is beneficial for health, but can be challenging given the role alcohol plays in the rituals of many social occasions. We examined how people who stopped or reduced their alcoh...
{ "pile_set_name": "PubMed Abstracts" }
Some aspects of the epidemiology, clinical manifestations, and diagnosis of human dirofilariasis caused by Dirofilaria repens. In recent years, zoonotic filariae Dirofilaria immitis and Dirofilaria (Nochtiella) repens are gaining popularity as incidental human parasitic pathogens. The usual hosts for these nematodes ar...
{ "pile_set_name": "PubMed Abstracts" }
Use of pulmonary capillary wedge aspirates for the antemortem diagnosis of pulmonary microvascular tumor. The diagnosis of pulmonary lymphangitic carcinoma usually requires fiberoptic bronchoscopy with transbronchial biopsy, percutaneous needle aspiration of the lung, and/or open lung biopsy. We performed right heart c...
{ "pile_set_name": "PubMed Abstracts" }
Endothelin stimulates steroid secretion by frog adrenal gland in vitro: evidence for the involvement of prostaglandins and extracellular calcium in the mechanism of actin of endothelin. Endothelin (ET-1) is a pleiotropic regulatory peptide which exerts multiple endocrine actions on the cardiovascular system. In the pre...
{ "pile_set_name": "PubMed Abstracts" }
Neutrophil-Kupffer-cell interaction in host defenses to systemic infections. Most relevant textbooks characterize phagocytosis by Kupffer cells as the principal mechanism for clearing bacterial pathogens from the bloodstream and eliminating them from the liver. Here, Stephen Gregory and Edward Wing discuss recent evide...
{ "pile_set_name": "PubMed Abstracts" }
Photochromic Hydrazone Switches with Extremely Long Thermal Half-Lives. A family of easily accessible light-activated hydrazone switches has been developed having thermal half-lives of up to 2700 years! Structure-property analysis shows that replacing the rotor pyridyl group of our typical hydrazone switch with a pheny...
{ "pile_set_name": "PubMed Abstracts" }
Trait anxiety and autonomic indicators of the processing of threatening information: a cued S1-S2 paradigm. The aim of this study was to use autonomic parameters in a cued S1-S2 task to examine associations between the processing of threatening information and trait anxiety in normal individuals. Forty-six student volu...
{ "pile_set_name": "PubMed Abstracts" }
[PulseNet Japan: surveillance system for the early detection of diffuse outbreak based on the molecular epidemiological method]. As the foods are stocked below freezing and widely distributed, a kind of food-borne outbreak which occurs in separate regions or in different time, so called "diffuse outbreak", has been fou...
{ "pile_set_name": "PubMed Abstracts" }
Biocompatibility of silver nitrate and ofloxacine coated bioabsorbable SR-PLLA rods. The purpose of this study was to evaluate the biocompatibility of silver nitrate and ofloxacine coatings of bioresorbable self-reinforced poly-L-lactic acid (SR-PLLA) rods. SR-PLLA rods coated with pure poly(caprolactone-co-L-lactide) ...
{ "pile_set_name": "PubMed Abstracts" }
Critical illness neuromuscular syndromes. Critical illness neuromyopathy (CINM) is the most common peripheral neuromuscular disorder encountered in the ICU. Bilateral diffuse weakness predominant in the proximal part of the limbs after improvement of the acute phase of the critical illness is highly suggestive of CINM....
{ "pile_set_name": "PubMed Abstracts" }
The Brief COPE: Factor Structure and Associations With Self- and Other-Directed Aggression Among Emerging Adults. The Brief COPE has seen frequent use across populations despite lack of confirmatory factor-analytic examination. We further examine Brief COPE validity with respect to self- and other-directed aggression b...
{ "pile_set_name": "PubMed Abstracts" }
Platelet rap1B phosphorylation is a sensitive marker for the action of cyclic AMP- and cyclic GMP-increasing platelet inhibitors and vasodilators. Rap1B, a ras-like protein expressed in high concentrations in human platelets, serves as a substrate for protein kinase A (PKA) and, eventually, protein kinase G (PKG). We m...
{ "pile_set_name": "PubMed Abstracts" }
Repair or Reconstruction in Acute Posterolateral Instability of the Knee: Decision Making and Surgical Technique Introduction. Complex knee injury surgeons must frequently decide whether to repair or reconstruct an acute posterolateral corner (PLC) injury. If repair is not feasible or fails, reconstruction is often nec...
{ "pile_set_name": "PubMed Abstracts" }
Chemical properties of water-soluble porphyrins. 5. Reactions of some manganese (III) porphyrins with the superoxide and other reducing radicals. Solution properties of three manganese porphyrins, in monomeric form, were investigated. These were the 'picket-fence-like' porphyrin Mn(III)-alpha,alpha,alpha,beta- tetra-or...
{ "pile_set_name": "PubMed Abstracts" }
Distinctive pro-inflammatory gene signatures induced in articular chondrocytes by oncostatin M and IL-6 are regulated by Suppressor of Cytokine Signaling-3. To describe gene expression in murine chondrocytes stimulated with IL-6 family cytokines and the impact of deleting Suppressor of Cytokine Signaling-3 (SOCS-3) in ...
{ "pile_set_name": "PubMed Abstracts" }
[Doping and urologic tumors]. Several substances such as growth hormone (GH), erythropoietin (Epo), and anabolic steroids (AS) are improperly utilized to increase the performance of athletes. Evaluating the potential cancer risk associated with doping agents is difficult since these drugs are often used at very high do...
{ "pile_set_name": "PubMed Abstracts" }
A longitudinal study to identify constraints to dairy cattle health and production in rural smallholder communities in Northern Vietnam. The objective of the study was to investigate constraints to dairy cattle health and production in rural smallholder communities in northern Vietnam, one of the target areas of the Vi...
{ "pile_set_name": "PubMed Abstracts" }
Prevalence of anaerobic ammonium-oxidizing bacteria in contaminated groundwater. Anaerobic ammonium-oxidizing (anammox) bacteria perform an important step in the global nitrogen cycle: anaerobic oxidation of ammonium and reduction of nitrite to form dinitrogen gas (N(2)). Anammox organisms appear to be widely distribut...
{ "pile_set_name": "PubMed Abstracts" }
[Mortality prognostic factors of cardiogenic shock complicating an acute myocardial infarction and treated by percutaneous coronary intervention]. To determine the in-hospital prognosis and late outcome of cardiogenic shock complicating acute myocardial infarction treated by early (< 24 hours) percutaneous coronary int...
{ "pile_set_name": "PubMed Abstracts" }
Human alkyladenine DNA glycosylase uses acid-base catalysis for selective excision of damaged purines. Human alkyladenine DNA glycosylase (AAG) protects against alkylative and oxidative DNA damage, flipping damaged nucleotides out of double-stranded DNA and catalyzing the hydrolytic cleavage of the N-glycosidic bond to...
{ "pile_set_name": "PubMed Abstracts" }
Peripheral gene expression profile of mechanical hyperalgesia induced by repeated cold stress in SHRSP5/Dmcr rats. Repeated cold stress (RCS) is known to transiently induce functional disorders associated with hypotension and hyperalgesia. In this study, we investigated the effects of RCS (24 and 4 °C alternately at 30...
{ "pile_set_name": "PubMed Abstracts" }
Xenografted human amniotic fluid-derived stem cell as a cell source in therapeutic angiogenesis. Amniotic fluid-derived stem cells (AFSCs) are pluripotent with high renewal capacity and are not tumorigenic. We tested whether AFSCs can function as a cell source for therapeutic angiogenesis in a mouse hindlimb ischemia m...
{ "pile_set_name": "PubMed Abstracts" }
Characteristics of rehabilitation services in high-FIM efficiency hospitals after hip fracture. Characteristics of rehabilitation services probably explain a large proportion of the variation in clinical outcomes following hip fracture. The aim of this study was to clarify rehabilitation characteristics of high-perform...
{ "pile_set_name": "PubMed Abstracts" }
Fasting times in caregivers of children presenting for ambulatory surgery. It has been the anecdotal experience in this unit that many parents and guardians of children presenting for day-case surgery also fast along with their child for prolonged periods of time. There have been several episodes of parents feeling diz...
{ "pile_set_name": "PubMed Abstracts" }
[Nursing education: integrating gender equity consciousness]. Gender sensitivity influences the way a nurse handles the nursing process and can influence both patient care and public perception of the nursing profession. Nurses unaware of the influences of gender are unable to perform holistic nursing, the practice of ...
{ "pile_set_name": "PubMed Abstracts" }
Treatment of tobacco addiction and the cardiovascular specialist. Tobacco smoking is the leading cause of avoidable deaths worldwide, and half of these deaths are due to cardiovascular disease (CVD). Physicians specialized in the management of CVD play a key role in ensuring that all smokers with cardiovascular disorde...
{ "pile_set_name": "PubMed Abstracts" }
Symposium: Normal and abnormal REM sleep regulation: REM sleep in successful, usual, and pathological aging: the Pittsburgh experience 1980-1993. Successful psychological and physical adaptation in late life correlates with preservation of sleep quality and physiological integrity of nocturnal EEG sleep measures. Failu...
{ "pile_set_name": "PubMed Abstracts" }
Some shallow-water hydroids (Cnidaria: Hydrozoa) from the central east coast of Florida, USA. This paper gives a systematic account of 67 species, referable to 22 families and 40 genera, identified in a small collection of hydroids from the central Atlantic coast of Florida between Melbourne and Palm Beach. The fauna m...
{ "pile_set_name": "PubMed Abstracts" }
[An analysis of combined desensitizing acupoints therapy in 419 cases of allergic rhinitis accompanying asthma]. To explore the effective therapy in treating allergic rhinitis accompanying asthma. A combined desensitizing therapy in treating 419 cases of allergic rhinitis accompanying asthma caused by allergens has bee...
{ "pile_set_name": "PubMed Abstracts" }
Open bite treatment using clear aligners. A 35-year-old female patient with dentoalveolar open bite of 4 mm, molar Class I malocclusion, centered midlines, moderate crowding, and labial inclination of the lower incisor was treated with clear aligners to reduce protrusion and close the anterior open bite. The result sho...
{ "pile_set_name": "PubMed Abstracts" }
STRA13 interacts with STAT3 and modulates transcription of STAT3-dependent targets. STRA13 is a pVHL-dependent bHLH transcription factor up-regulated on the mRNA level in multiple cancer cell lines and implicated recently in the regulation of immune cell homeostasis and autoimmunity. In searching for STRA13-interacting...
{ "pile_set_name": "PubMed Abstracts" }
[Treatment of neuromyelitis optica]. Neuromyelitis optica (NMO) or Devic's disease is an inflammatory neurologic disease characterized by severe optic neuritis and transverse myelitis. Other features of NMO include female preponderance, higher onset age, severe functional disability, longitudinally extensive spinal cor...
{ "pile_set_name": "PubMed Abstracts" }
Caffeine consumption and anxiety and depressive symptomatology among medical students. Caffeine is one of the most widely consumed psychoactive substances in the world and is ingested in a variety of favorites, such as coffee, tea, cola and so on. Although it has been suggested that high dose caffeine users have more a...
{ "pile_set_name": "PubMed Abstracts" }
New adjuvants: EU regulatory developments. This paper discusses EU regulatory texts that are relevant for the introduction of new adjuvants in human vaccines and discusses the EU requirements at the developmental level, during the manufacturing process and at the final product stage. The emphasis is on regulatory expec...
{ "pile_set_name": "PubMed Abstracts" }
Infectious agents and age-related neurodegenerative disorders. chlamdAs with other organ systems, the vulnerability of the nervous system to infectious agents increases with aging. Several different infectious agents can cause neurodegenerative conditions, with prominent examples being human immunodeficiency virus (HIV...
{ "pile_set_name": "PubMed Abstracts" }
[Venous ulcer on the hand due to a treatment-related arteriovenous fistula]. An arteriovenous fistula of the arm for hemodialysis needs to last long and provide easy access for puncture. A 50 year-old woman, with type 2 diabetes complicated by chronic renal failure, presented with an ulcer on the dorsum of the right ha...
{ "pile_set_name": "PubMed Abstracts" }
Involvement of oxidative stress, NF-IL-6, and RANTES expression in dengue-2-virus-infected human liver cells. The liver has been suspected to be one of the major targets of dengue virus infection. Here, we detected increasing secretion of the chemokine RANTES (regulated upon activation, normal T cell expressed and secr...
{ "pile_set_name": "PubMed Abstracts" }
[Ultrasound in the diagnostics of fatty liver in obesity]. Chronic diffuse liver diseases produce a characteristic ultrasound image called bright liver. On the basis of liver attenuation, two major appearances can be observed: low and high attenuation types. It is proved that high attenuation is associated with fatty l...
{ "pile_set_name": "PubMed Abstracts" }
Short- and long-term influence of the levonorgestrel-releasing intrauterine system (Mirena®) on vaginal microbiota and Candida. Recurrent vulvovaginal infections are a frequent complaint in young women in need of contraception. However, the influence of the contraceptive method on the course of the disease is not well ...
{ "pile_set_name": "PubMed Abstracts" }
Light- and electron microscopic characteristics of the vegetative centers in the guinea pig sacral spinal cord intermediate zone. A dense AChE-negative and NA fluorescent network was visualized by light microscopy in the sacral spinal cord intermediate zone of grown-up guinea pigs of both sexes. This network connects i...
{ "pile_set_name": "PubMed Abstracts" }
Association of Mean Platelet Volume with Acute Ischemic Cerebrovascular Accident Among Patients with Type 2 Diabetes Mellitus: A Hospital-Based Study. To study the association of MPV (mean platelet volume) and acute ischemic stroke in patients of type 2 diabetes mellitus (DM). This was a 1-year cross-sectional hospital...
{ "pile_set_name": "PubMed Abstracts" }
First and Second Step Characteristics of Amputee and Able-Bodied Sprinters. In sprint events, the first 2 steps are used to accelerate the center of mass horizontally and vertically. Amputee athletes cannot actively generate energy with their running-specific prosthesis. It is likely that sprint acceleration mechanics,...
{ "pile_set_name": "PubMed Abstracts" }
Halomonas beimenensis sp. nov., isolated from an abandoned saltern. A Gram-staining negative, motile, non-spore-forming, short rod-shaped (0.8-1.5 × 1.5-2.0 µm), halophilic bacterium, designated strain NTU-107(T), was isolated from brine samples collected from the abandoned Beimen saltern in southern Taiwan. The novel ...
{ "pile_set_name": "PubMed Abstracts" }
Regulation of bone lysis in inflammatory diseases. Focal bone erosion is a major pathological feature of several common inflammatory diseases. Over the past decade there have been major advances in our understanding of the factors that regulate osteoclast formation and activity. It is now apparent that receptor activat...
{ "pile_set_name": "PubMed Abstracts" }
[Choice of antibiotic therapy for acute streptococcus A sore throat: new bacteriologic data]. The choice of antibiotic therapy for sore throat of bacterial origin must be directed against the beta-haemolytic streptococcus A, or more rarely C and G. Recent bacteriological data confirm the raised and constant antibacteri...
{ "pile_set_name": "PubMed Abstracts" }
Purification, crystallization and preliminary crystallographic studies of an integral membrane protein, cytochrome bo3 ubiquinol oxidase from Escherichia coli. Cytochrome bo(3) ubiquinol oxidase has been successfully purified for crystallization. Single crystals of this integral membrane protein diffract X-rays to 3.5 ...
{ "pile_set_name": "PubMed Abstracts" }
Intercalation of 3-phenyl-1-proponal into OTS SAMs on silica nanoasperities to create self-repairing interfaces for MEMS lubrication. Self-assembled monolayers (SAMs) have been widely studied as potential lubricants for microelectromechanical system (MEMS) devices. However, these single-layer films have nominally been ...
{ "pile_set_name": "PubMed Abstracts" }
Gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway. Radiotherapy is a widespread treatment in human solid tumors. However, therapy resistance and poor prognosis are still problems. Gambogic acid (GA), extracted from the dried y...
{ "pile_set_name": "PubMed Abstracts" }
The 'medical body' as philosophy's arena. Medicine, as Byron Good argues, reconstitutes the human body of our daily experience as a "medical body," unfamiliar outside medicine. This reconstitution can be seen in two ways: (i) as a salutary reminder of the extent to which the reality even of the human body is constructe...
{ "pile_set_name": "PubMed Abstracts" }
Countervailing social network influences on problem behaviors among homeless youth. The impact of countervailing social network influences (i.e., pro-social, anti-social or HIV risk peers) on problem behaviors (i.e., HIV drug risk, HIV sex risk or anti-social behaviors) among 696 homeless youth was assessed using struc...
{ "pile_set_name": "PubMed Abstracts" }
Feedback control of glomerular filtration rate in isolated, blood-perfused dog kidneys. Micropuncture studies were done in isolated, blood-perfused dog kidneys to investigate the intrarenal nature of tubuloglomerular feedback regulation of nephron filtration rate. Collections were made at early proximal tubular sites d...
{ "pile_set_name": "PubMed Abstracts" }
Secondary hyperparathyroidism in diabetic and nondiabetic patients on long-term continuous ambulatory peritoneal dialysis (CAPD). Serum values of calcium, phosphate, alkaline phosphatases and parathyroid hormone (PTH) are reported for 24 diabetic and 26 nondiabetic patients treated with continuous ambulatory peritoneal...
{ "pile_set_name": "PubMed Abstracts" }
[A case of infantile virilizing adrenocortical tumor]. The patient was a 16-month-old girl, born by mature natural delivery and weighing 3,320 g. Hirsutism was noted on birth. Development of pubic hair and hypertrophy of the labia minora were noted after 8 months. At the time of admission, the height was 80 cm and body...
{ "pile_set_name": "PubMed Abstracts" }
Hydroxyproline-rich protein in the capsule of a strain of Staphylococcus aureus. A protein fraction containing a high amount of hydroxyproline was found in the capsule of the Smith diffuse strain (encapsulated) when compared with that of dialysate medium. This content varied depending upon temperature, oxygen supply, s...
{ "pile_set_name": "PubMed Abstracts" }
Delay in diagnosis of breast cancer. A professional liability risk. This article notes that liability claims of failure to diagnose breast cancer are increasing in number and severity, at least in part because women understand that early diagnosis improves survival. Legal cases are presented that illustrate particular ...
{ "pile_set_name": "PubMed Abstracts" }
Single crystalline magnetite nanotubes. We descried a method to synthesize single crystalline Fe3O4 nanotubes by wet-etching the MgO inner cores of MgO/Fe3O4 core-shell nanowires. Homogeneous Fe3O4 nanotubes with controllable length, diameter, and wall thickness have been obtained. Resistivity of the Fe3O4 nanotubes wa...
{ "pile_set_name": "PubMed Abstracts" }
Raman spectroscopy of breast tissues. Breast cancer is one of the leading female cancers. The major drawback of the gold standard of screening, mammography, is the high rate of false reports, aside from the risk from repeated exposure to harmful ionizing radiations. Histopathology, the gold standard of diagnosis, is ti...
{ "pile_set_name": "PubMed Abstracts" }
New perspectives in the diagnosis of Echinococcus disease. Echinococcosis, an endemic disease on the Asian continent, is caused by the tapeworm Tenia Echinococcus, which produces cysts in the liver and other organs. I reviewed 157 patients with hydatid disease of the liver. The hydatid cysts were single in 125 patients...
{ "pile_set_name": "PubMed Abstracts" }
Regulation of D-amino acid oxidase expression in the yeast Rhodotorula gracilis. Rhodotorula gracilis is a oleaginous yeast which utilizes D-amino acids as a source of carbon and/or nitrogen. D-amino acid oxidase (DAAO), which converts D-amino acids in the corresponding alpha-keto acids and ammonia, is the first enzyme...
{ "pile_set_name": "PubMed Abstracts" }
Identification, clinical-pathological characteristics and treatment outcomes of patients with metastatic breast cancer and somatic human epidermal growth factor receptor 2 (ERBB2) mutations. The human epidermal growth factor receptor 2 (ERBB2) may harbour somatic mutations that drive breast tumorigenesis. Here, we stud...
{ "pile_set_name": "PubMed Abstracts" }
Histamine H3 Receptor Ligands in the Group of (Homo)piperazine Derivatives. Since its discovery in 1983, followed by gene cloning in 1999, the histamine H3 receptor served as an outstanding target for drug discovery. The wide spectrum of possible therapeutic implications makes H3R's one of the most researched areas in ...
{ "pile_set_name": "PubMed Abstracts" }
A Synaptic Basis for GLP-1 Action in the Brain. Unraveling the brain control of metabolism may generate opportunities to discover novel precision medicines for obesity and diabetes. In this issue of Neuron, Liu et al. (2017) identify a novel glucagon-like peptide (GLP)-1 receptor-dependent signaling process that exerts...
{ "pile_set_name": "PubMed Abstracts" }
High expression of DNA repair pathways is associated with metastasis in melanoma patients. We have identified a gene-profile signature for human primary malignant melanoma associated with metastasis to distant sites and poor prognosis. We analyse the differential gene expression by looking at whole biological pathways ...
{ "pile_set_name": "PubMed Abstracts" }
[Inhibition of the expression of prostate specific antigen by curcumin]. To study the effect of curcumin on the expression of prostate specific antigen (PSA). AXSYM system-chemical luciferase method was used to examine the content of PSA in prostate cancer cell lines, LNCap after treated with different doses of curcumi...
{ "pile_set_name": "PubMed Abstracts" }
Conjugated linoleic acid increased C-reactive protein in human subjects. We previously showed that conjugated linoleic acid (CLA) increases 15-keto-dihydro-prostaglandin F2alpha, a marker for cyclooxygenase-mediated lipid peroxidation and thus an indicator of cyclooxygenase-mediated inflammation. The aim of the present...
{ "pile_set_name": "PubMed Abstracts" }
c-Met expression is regulated by Mitf in the melanocyte lineage. Hepatocyte growth factor (HGF)/c-Met signaling is thought to be a key pathway in both melanocyte development and melanoma metastasis. Here, HGF stimulation of melanocytes was seen to up-regulate c-Met expression. In an effort to decipher the mechanism by ...
{ "pile_set_name": "PubMed Abstracts" }
Inhibition of steroidogenic response to corticotropin in mouse adrenal tumor cells (Y-1) by the ionophore A23187. Role of protein biosynthesis. Addition of the ionophore A23187 to Y-1 mouse adrenal tumor cells in monolayer culture inhibits steroidogenesis and the steroidogenic response to corticotropin (50% inhibition ...
{ "pile_set_name": "PubMed Abstracts" }
[Progress in streptothricin antibiotics - A review]. Streptothricins are a group of the earliest discovered antibiotics with broad antimicrobial spectrum, and have been used for crop protection. We reviewed the studies on streptothricin resistance, biosynthesis of the three components (streptolidine, carbamoylated D-gl...
{ "pile_set_name": "PubMed Abstracts" }