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Identification of type II procollagen in rabbit vitreous. A procollagen in the soluble fraction of rabbit vitreous was isolated by dialysis against dilute acetic acid and partially purified by Bio-Gel A 5M gel filtration. The molecule was identified to be type II procollagen by comparing its segment-long-spacing (SLS) ...
{ "pile_set_name": "PubMed Abstracts" }
Aplasia cutis congenita, elevated alpha-fetoprotein, and a distinct amniotic fluid acetylcholinesterase electrophoretic band. Aplasia cutis congenita affecting the elbows, knees, hips, and gluteal area was observed in a female newborn, product of a twin pregnancy. One of the twins was a fetus papyraceous detected at 15...
{ "pile_set_name": "PubMed Abstracts" }
[On the occasion of unveiling a memorial plaque to Dr. Bozidar Spisic]. The first rehabilitation center was founded and organized in Zagreb, 1908, by prof. dr. Bozidar Sisić. Its importance was stressed through the history, as unique and first in this part of Europe. On the occasion of the 90th anniversary of its found...
{ "pile_set_name": "PubMed Abstracts" }
Pathologic fracture of the mandible associated with simultaneous occurrence of an odontogenic keratocyst and traumatic bone cyst. A case is presented which involved a pathologic fracture of the mandible associated with a large radiolucent lesion extending from the parasymphysis to the coronoid notch. The osseous defect...
{ "pile_set_name": "PubMed Abstracts" }
Predictors of sick leave and reduced productivity at work among persons with early inflammatory joint conditions. This study attempted to identify predictors of sick leave and reduced productivity at work among persons with early inflammatory joint conditions. In a prospective cohort study of 210 workers with inflammat...
{ "pile_set_name": "PubMed Abstracts" }
Evidence against chronic antigen-specific T lymphocyte activation in myasthenia gravis. Myasthenia gravis (MG) is an antigen-specific autoimmune disease caused by antibodies against acetylcholine receptors (AChR) at the post-synaptic membrane of the neuromuscular junction. Clinical and immunological data imply the invo...
{ "pile_set_name": "PubMed Abstracts" }
Lipid droplet accumulation and lipoprotein lipase activity in the rat salivary gland during the perinatal period. The submandibular and sublingual glands of foetal and newborn rats aged 21 days in utero to 7 days after birth were examined morphologically and biochemically. Lipid droplets tended to be localized in secre...
{ "pile_set_name": "PubMed Abstracts" }
Auditive stimulation therapy as an intervention in subacute and chronic tinnitus: a prospective observational study. Tinnitus is a noise, a ringing, or a roaring sound in the affected ear and is becoming an increasingly serious problem for health care systems. Integrative treatment concepts are currently regarded as pr...
{ "pile_set_name": "PubMed Abstracts" }
The use of endo-GIA vascular staplers in liver surgery and their potential benefit: a review. Stapling devices have been introduced for safety and to reduce the overall operative time in many surgical procedures. In hepatobiliary surgery, i.e. liver resection, several types of staplers are in use. While transection of ...
{ "pile_set_name": "PubMed Abstracts" }
Plasma vitamin A composition and retinol-binding protein concentration during egg formation in laying hens. Blood plasma vitamin A composition (retinol, retinyl ester) and retinol-binding protein (RBP) were determined in three phases (empty; soft- and hard egg) of the egg formation period in laying hens. The retinyl es...
{ "pile_set_name": "PubMed Abstracts" }
Circular beams. A very general beam solution of the paraxial wave equation in circular cylindrical coordinates is presented. We call such a field a circular beam (CiB). The complex amplitude of the CiB is described by either the Whittaker functions or the confluent hypergeometric functions and is characterized by three...
{ "pile_set_name": "PubMed Abstracts" }
Reconstructing the hidden states in time course data of stochastic models. Parameter estimation is central for analyzing models in Systems Biology. The relevance of stochastic modeling in the field is increasing. Therefore, the need for tailored parameter estimation techniques is increasing as well. Challenges for para...
{ "pile_set_name": "PubMed Abstracts" }
Improvement of the embalming perfusion method: the innovation and the results by light and scanning electron microscopy. Embalming is a chemical process that aims the preservation and sanitization of the human body indefinitely. The technique of embalming is an important tool in teaching and research in anatomy enablin...
{ "pile_set_name": "PubMed Abstracts" }
Selective inhibition and naming performance in semantic blocking, picture-word interference, and color-word Stroop tasks. In 2 studies, we examined whether explicit distractors are necessary and sufficient to evoke selective inhibition in 3 naming tasks: the semantic blocking, picture-word interference, and color-word ...
{ "pile_set_name": "PubMed Abstracts" }
Mental health and the response to financial incentives: Evidence from a survey incentives experiment. Although mental health disorders such as anxiety and depression are common, there is little research on whether individuals in poor mental health react differently from others to financial incentives. This paper exploi...
{ "pile_set_name": "PubMed Abstracts" }
Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthma. Protease-activated receptors (PARs), which are G protein-coupled receptors that are activated after proteolytic cleavage of the amino terminus of the receptor, are likely to play a major role in air...
{ "pile_set_name": "PubMed Abstracts" }
The role of basic sciences in diagnostic oral radiology. Although it is generally taken for granted that dental education must include both basic science and feature-based knowledge components, little is known about their relative roles in visual interpretation of radiographs. The objectives of this study were twofold....
{ "pile_set_name": "PubMed Abstracts" }
Effect of the abrasive properties of sedges on the intestinal absorptive surface and resting metabolic rate of root voles. Recent studies on grasses and sedges suggest that the induction of a mechanism reducing digestibility of plant tissues in response to herbivore damage may drive rodent population cycles. This defen...
{ "pile_set_name": "PubMed Abstracts" }
Mass spectrometry for rapid characterization of microorganisms. Advances in instrumentation, proteomics, and bioinformatics have contributed to the successful applications of mass spectrometry (MS) for detection, identification, and classification of microorganisms. These MS applications are based on the detection of o...
{ "pile_set_name": "PubMed Abstracts" }
Conversations about binge drinking among vocational community college students: the relation with drinking attitudes and intentions and the moderating role of conversation partner popularity. Objective: The association between conversational valence (i.e. how positive/negative people perceive their conversations to be)...
{ "pile_set_name": "PubMed Abstracts" }
An electric cutter for all surgical prostheses. A new electric cutter for surgical prostheses has been developed and was compared with surgical scissors for efficacy. This comparison of the two methods was done by cutting the edges of nine popular prostheses. It was concluded from gross and microscopical results after ...
{ "pile_set_name": "PubMed Abstracts" }
Use and toxicity of the colony-stimulating factors. The colony-stimulating factors (CSFs) have emerged as effective drugs in a variety of clinical situations. These drugs stimulate the production and activity of haematopoietic cells in vitro and in vivo. Two members of this group, granulocyte CSF (G-CSF) and granulocyt...
{ "pile_set_name": "PubMed Abstracts" }
Shelf-life extension of semi-dried buckwheat noodles by the combination of aqueous ozone treatment and modified atmosphere packaging. The present study investigated the combined effects of aqueous ozone treatment and modified atmosphere packaging (MAP) on prolonging the shelf-life of semi-dried buckwheat noodles [SBWN;...
{ "pile_set_name": "PubMed Abstracts" }
KF26777 (2-(4-bromophenyl)-7,8-dihydro-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one dihydrochloride), a new potent and selective adenosine A3 receptor antagonist. We investigated the biochemical and pharmacological properties of a new adenosine A(3) receptor antagonist, KF26777 (2-(4-bromophenyl)-7,8-dihydro-4-propyl-1H-i...
{ "pile_set_name": "PubMed Abstracts" }
Functional expression of CXC chemokine recepter-4 mediates the secretion of matrix metalloproteinases from mouse hepatocarcinoma cell lines with different lymphatic metastasis ability. CXC chemokine recepter-4 (CXCR4) and its ligand, stromal cell-derived factor-1alpha (SDF-1alpha) have been implicated in the organ-spec...
{ "pile_set_name": "PubMed Abstracts" }
[Influence of endogenous factors on the ash, calciu, magnesium, potassium, sodium, phosphorus, zinc, iron, copper and manganese contents in the bristles of pigs. 4. Effect of time of cutting and heredity on the inorganic components in the hair of the pigs (bristles of sows and piglets, newly grown hair)]. Samples of so...
{ "pile_set_name": "PubMed Abstracts" }
Posttraumatic stress symptoms in adolescent survivors of childhood cancer and their mothers. We examined symptoms of posttraumatic stress disorder (PTSD) in adolescent survivors of childhood cancer and their mothers and the contribution of family functioning, including perceived emotional support and familial conflict,...
{ "pile_set_name": "PubMed Abstracts" }
The synthesis of 7 alpha-methyl-substituted estrogens labeled with fluorine-18: potential breast tumor imaging agents. The 7 alpha-methyl substituent is reported to increase the binding affinity of estradiol for the estrogen receptor (ER). In order to evaluate whether this substituent would improve the in vitro binding...
{ "pile_set_name": "PubMed Abstracts" }
Quantitative determinations of immunoglobulins and complement components in human aortic atherosclerotic wall. Saline and acid eluates of intima with only fatty streaks, fibrous plaque and intima surrounding the fibrous plaque were obtained from 42 human aortae. IgG, IgA, IgM, C1q, C3c, C4, C9, C3A, C-reactive protein,...
{ "pile_set_name": "PubMed Abstracts" }
[The role of disturbances in the hormonal signaling systems in etiology and pathogenesis of diabetes mellitus]. The role of disturbances in the hormonal signaling systems of brain and peripheral tissues in etiology and pathogenesis of diabetes mellitus (DM) of the types 1 and 2 is discussed. Available data confirming t...
{ "pile_set_name": "PubMed Abstracts" }
How to build optically active alpha-amino acids. Various methodologies published in the literature dealing with alpha-amino carboxylic acid asymmetric synthesis are presented in a digest form. In each case, only some recent or most typical works are mentioned.
{ "pile_set_name": "PubMed Abstracts" }
Transcriptional regulation by infliximab therapy in Kawasaki disease patients with immunoglobulin resistance. Infliximab (IFX), a known monoclonal antibody against tumor necrosis factor-α (TNF-α), is used to treat Kawasaki disease (KD) patients with intravenous immunoglobulin (IVIG) resistance. The transcriptional modu...
{ "pile_set_name": "PubMed Abstracts" }
Effects of various neuroleptics on rabbit hyperthermia induced by N, N-Dimethyltryptamine (DMT) and d-amphetamine. The effects of various neuroleptics were studied on N, N-dimethyltryptamine (DMT, 3.2 mg/kg) and d-amphetamine (3.2 mg/kg) induced hyperthermia in the rabbit. Complete dose-effect curves were obtained. The...
{ "pile_set_name": "PubMed Abstracts" }
Complex effects of interleukin 6 on clonogenic blast cell growth in acute myeloblastic leukemia. The present in vitro study shows how interleukin (IL)-6 modulates clonogenic blast cell growth in complex ways in acute myeloblastic leukemia when used either as a single factor or in different hematopoietic growth factor c...
{ "pile_set_name": "PubMed Abstracts" }
Smoking Prevalence Among Users of Primary Healthcare Units in Brazil: The Role of Religiosity. The objective of this cross-sectional study is to examine the association between religious involvement and tobacco use in a large representative sample of users of primary healthcare units of Ribeirão Preto, Southeast Brazil...
{ "pile_set_name": "PubMed Abstracts" }
Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer's disease. The progressive accumulation of extracellular amyloid plaques in the brain is a common hallmark of Alzheimer's disease (AD). We recently identified a novel species of Aβ phosphorylated at serine r...
{ "pile_set_name": "PubMed Abstracts" }
Preventing unintended pregnancies and improving contraceptive use among young adult women in a rural, Midwestern state: health promotion implications. Despite high rates of unintended pregnancy among women aged 18 to 30 years, little research has been conducted to understand the factors associated with their contracept...
{ "pile_set_name": "PubMed Abstracts" }
Relaxed rrn expression and amino acid requirement of a Corynebacterium glutamicum rel mutant defective in (p)ppGpp metabolism. The stringent response in Corynebacterium glutamicum was investigated. Sets of rrn-cat fusions were constructed in their native chromosomal position to examine the effects of amino acid starvat...
{ "pile_set_name": "PubMed Abstracts" }
Multi-locus species delimitation in closely related animals and fungi: one marker is not enough. Despite taxonomy's 250-year history, the past 20 years have borne witness to remarkable advances in technology and techniques, as well as debate. DNA barcoding has generated a substantial proportion of this debate, with its...
{ "pile_set_name": "PubMed Abstracts" }
Simultaneous ocular and systemic cysticercosis and tuberculosis. Human cysticercosis and tuberculosis are endemic diseases in developing countries. Both these diseases have certain common factors of origin. We would like to present the co-existence of these infections in a 20-year-old female. She was a known case of pu...
{ "pile_set_name": "PubMed Abstracts" }
[A change of the medium salinity as a functional load for evaluation of physiological state of the crayfish Astacus leptodactylus]. The necessity of developing criteria for evaluation of the functional state of benthic invertebrates for toxicological studies or for their use as biosensors in systems of the water qualit...
{ "pile_set_name": "PubMed Abstracts" }
Antioxidant activity of diterpenes and polyphenols from Ophryosporus heptanthus. The antioxidant activity of 14 compounds (1-14) isolated from the ether and butanolic extracts of the aerial parts of Ophryosporus heptanthus has been assayed using a beta-carotene bleaching method and the DPPH technique. Compounds 1 and 1...
{ "pile_set_name": "PubMed Abstracts" }
Hemocyanin from Tachypleus gigas. II. Cooperative interactions of the subunits. Six subunits (I to VI) were isolated from hemocyanin of an Asian horseshoe crab, Tachypleus gigas, by anion exchange chromatography of the dissociated hemocyanin. The subunit preparations were nearly homogeneous as judged by alkaline electr...
{ "pile_set_name": "PubMed Abstracts" }
IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes. The long-held view that many autoimmune disorders are primarily driven by a Th1 response has been challenged by the discovery of Th17 cells. Since the identification of this distinct T cell subset, Th17 cells have been implicated in the p...
{ "pile_set_name": "PubMed Abstracts" }
Psychological Determinants of Heart Failure Self-Care: Systematic Review and Meta-Analysis. Psychological distress has been associated with poor outcomes in patients with chronic heart failure (HF), which is assumed to be partly due to poor HF self-care behavior. This systematic review and meta-analysis describes the c...
{ "pile_set_name": "PubMed Abstracts" }
Selective growth and ordering of SiGe nanowires for band gap engineering. Selective growth and self-organization of silicon-germanium (SiGe) nanowires (NWs) on focused ion beam (FIB) patterned Si(111) substrates is reported. In its first step, the process involves the selective synthesis of Au catalysts in SiO₂-free ar...
{ "pile_set_name": "PubMed Abstracts" }
Immunization update: a community-based nursing education program. Nurses play key roles as advocates, educators, and researchers to eliminate barriers to access as well as educate the public on the importance of vaccines for children in the United States. Fifty-four nurses attending a community-based immunization progr...
{ "pile_set_name": "PubMed Abstracts" }
Neonatal Morbidity Count Is Associated With a Reduced Likelihood of Achieving Recommendations for Protein, Lipid, and Energy in Very Low Birth Weight Infants: A Prospective Cohort Study. Serious morbidity may elevate nutrient requirements and affect adherence to feeding guidelines for very low birth weight (VLBW) infan...
{ "pile_set_name": "PubMed Abstracts" }
[Prevention of extremities amputation in patients with diabetic foot complications]. In order to decrease the number of amputations for "diabetic foot", these patients should undergo elective or delayed operations. It is obligatory before the operation to correct carbohydrate metabolism and hemodynamics. Sodium succina...
{ "pile_set_name": "PubMed Abstracts" }
Synthesis and photochemical properties of a novel iron-sulfur-nitrosyl cluster derivatized with the pendant chromophore protoporphyrin IX. The novel Roussin red-salt ester (PPIX-RSE) with a pendant porphyrin chromophore was prepared and investigated as a precursor for the photochemical generation of nitric oxide. PPIX-...
{ "pile_set_name": "PubMed Abstracts" }
Addition-subtraction osteotomy with ligamentoplasty for symptomatic trapezial dysplasia with metacarpal instability. Trapeziometacarpal instability with trapezial dysplasia is a disabling condition long before the radiological changes of osteoarthritis appear. In dysplastic joints surgical soft tissue correction fails ...
{ "pile_set_name": "PubMed Abstracts" }
Blood levels of cadmium and lead in relation to breast cancer risk in three prospective cohorts. Cadmium and lead have been classified as carcinogens by the International Agency for Research on Cancer. However, their associations with breast cancer risk are unknown despite their persistence in the environment and ubiqu...
{ "pile_set_name": "PubMed Abstracts" }
The tumour suppressor, miR-137, inhibits malignant melanoma migration by targetting the TBX3 transcription factor. The transcription factor, TBX3, is a key driver of malignant melanoma and any drug that impacts its expression is likely to have an impact on the treatment of this highly aggressive and treatment resistant...
{ "pile_set_name": "PubMed Abstracts" }
Surface immobilization of bio-functionalized cubosomes: sensing of proteins by quartz crystal microbalance. A strategy for tethering lipid liquid crystalline submicrometer particles (cubosomes) to a gold surface for the detection of proteins is reported. Time-resolved quartz crystal microbalance (QCM-D) was used to mon...
{ "pile_set_name": "PubMed Abstracts" }
Scutellaria baicalensis, a herbal medicine: anti-proliferative and apoptotic activity against acute lymphocytic leukemia, lymphoma and myeloma cell lines. Scutellaria baicalensis (S.B.) is a widely used Chinese herbal medicine. We initially investigated its in vitro anti-tumor activities. S.B inhibited the growth of AL...
{ "pile_set_name": "PubMed Abstracts" }
Acquisition of chemoresistance to gemcitabine is induced by a loss-of-function missense mutation of DCK. The anti-tumor activity of gemcitabine (GEM) has been clinically proven in several solid tumors, including pancreatic cancer, biliary tract cancer, urinary bladder cancer, and non-small cell lung cancer. However, pr...
{ "pile_set_name": "PubMed Abstracts" }
[Overview of lymphoid neoplasms in the fourth edition of the WHO classification]. The fourth edition of the "WHO Classification of Tumours of Haematopoietic and Lymphoid tissues" was published in 2008 as an updated version of the third edition published in 2001. In this review, the revised points in the lymphoid neopla...
{ "pile_set_name": "PubMed Abstracts" }
Temperature-dependent formation of octadecylsiloxane self-assembled monolayers on mica as studied by atomic force microscopy. We have investigated the growth of octadecylsiloxane (ODS) self-assembled monolayers on mica. Freshly cleaved muscovite mica and octadecyltrichlorosilane (OTS) dissolved in toluene (c = 1.0 mmol...
{ "pile_set_name": "PubMed Abstracts" }
Correlation between dissociation and catalysis of SARS-CoV main protease. The dimeric interface of severe acute respiratory syndrome coronavirus main protease is a potential target for the anti-SARS drug development. We have generated C-terminal truncated mutants by serial truncations. The quaternary structure of the e...
{ "pile_set_name": "PubMed Abstracts" }
Audiograms of three subterranean rodent species (genus Fukomys) determined by auditory brainstem responses reveal extremely poor high-frequency hearing. Life underground has shaped the auditory sense of subterranean mammals, shifting their hearing range to low frequencies. Mole-rats of the genus Fukomys have, however, ...
{ "pile_set_name": "PubMed Abstracts" }
[Evaluation of the degree of tryptophan residue immersion into the lipid phase of low density serum lipoproteins]. Based on the theory of inductive resonance energy transfer, it was demonstrated that in a two-phase waterlipid system the efficiency of the transfer from the donor to the acceptor, which is evenly distribu...
{ "pile_set_name": "PubMed Abstracts" }
Pros and cons of automatic milking in Europe. During the last several decades, new milking management systems have been introduced, of which development of automatic milking (AM) systems is a significant step forward. In Europe, AM has become an established management system and has shown to be much more than milking m...
{ "pile_set_name": "PubMed Abstracts" }
Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer. Ataxia-telangiectasia is characterized by radiosensitivity, genome instability and predisposition to cancer. Heterozygous carriers of ATM, the gene defective in ataxia-telangiectasia, have a high...
{ "pile_set_name": "PubMed Abstracts" }
Compressive force-produced CCN2 induces osteocyte apoptosis through ERK1/2 pathway. Osteocytes produce various factors that mediate the onset of bone formation and resorption and play roles in maintaining bone homeostasis and remodeling in response to mechanical stimuli. One such factor, CCN2, is thought to play a sign...
{ "pile_set_name": "PubMed Abstracts" }
Natural Disasters and Public Health. 2018 brought multiple, unprecedented natural disasters, including hurricanes, floods, and in the United States, the deadliest wildfire in California's history. After the immediate emergency is over and the media attention wanes, communities must deal with the long process of recover...
{ "pile_set_name": "PubMed Abstracts" }
Evaluation of a commercial exoantigen test system for the rapid identification of systemic fungal pathogens. Seventy-nine mycelial-form stock cultures of Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum, and morphologically similar fungi were extracted and tested by using commercial macroimmunodif...
{ "pile_set_name": "PubMed Abstracts" }
Percutaneous bypass: subintimal recanalization of peripheral occlusive disease with IVUS guided luminal re-entry. Angioplasty of chronic total occlusions (CTOs) has lower technical success rates with longer procedure times and poorer outcomes. Subintimal recanalization remains limited by the lack of controlled re-entry...
{ "pile_set_name": "PubMed Abstracts" }
[Discussion on randomized controlled trials about clinical researches of acupuncture and moxibustion medicine]. The characteristics of clinical tests of acupuncture and moxibustion were analyzed by studies of the literature about clinical evidence-based trials of acupuncture and moxibustion medicine at present and on t...
{ "pile_set_name": "PubMed Abstracts" }
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. In contrast to stably repressive, constitutive heterochromatin and stably active, euchromatin, facultative heterochromatin has the capacity to alternate between repressive and activated states of transcription. As such, it is an in...
{ "pile_set_name": "PubMed Abstracts" }
Aβ43 is the earliest-depositing Aβ species in APP transgenic mouse brain and is converted to Aβ41 by two active domains of ACE. Amyloid-β protein (Aβ) varies in length at its carboxyl terminus. The longer Aβ species, Aβ43 and Aβ42, are highly amyloidogenic and deposit more frequently than Aβ40 in the brain of Alzheimer...
{ "pile_set_name": "PubMed Abstracts" }
Toxic nodular goiter and cancer: a compelling case for thyroidectomy. Recent American Thyroid Association guidelines call for thyroidectomy or (131)I (Recommendation 31) in managing hyperthyroidism due to toxic nodular goiter (TNG). Concern for concomitant malignancy favors surgery. A 3 % thyroid cancer incidence in TN...
{ "pile_set_name": "PubMed Abstracts" }
Anabolic-androgenic steroid and adrenal steroid effects on hippocampal plasticity. Anabolic-androgenic steroids (AAS) are synthetic androgen-like compounds which are taken in high doses by athletes with the intention of enhancing muscular appearance, strength and/or athletic performance. Recent research indicates that ...
{ "pile_set_name": "PubMed Abstracts" }
Wavelet PCA for automatic identification of walking with and without an exoskeleton on a treadmill using pressure and accelerometer sensors. Nowadays portable devices with more number of sensors are used for gait assessment and monitoring for elderly and disabled. However, the problem with using multiple sensors is tha...
{ "pile_set_name": "PubMed Abstracts" }
Transient thrombopoietin peak after liver transplantation for end-stage liver disease. Knowledge about synthesis of thrombopoietin (TPO) by human liver cells is now well established and makes the study of TPO serum levels and interdependency with platelet concentrations important before and after liver transplantation....
{ "pile_set_name": "PubMed Abstracts" }
Clinical Value of Ultrasonography in Diagnosing Diffuse Thyroid Diseases Accompanied with Suspicious Nodules. To investigate the diagnostic value of ultrasonography for diffuse thyroid disease accompanied with suspicious nodules. A total of 148 patients with diffuse thyroid diseases accompanied with suspicious nodules ...
{ "pile_set_name": "PubMed Abstracts" }
Single-dose intravenous iron infusion or oral iron for treatment of fatigue after postpartum haemorrhage: a randomized controlled trial. To evaluate the clinical efficacy of a single-dose intravenous infusion of iron isomaltoside compared with current treatment practice with oral iron measured by physical fatigue in wo...
{ "pile_set_name": "PubMed Abstracts" }
[Posttetanic changes in the background gamma oscillations in interhemispheric interactions]. The influence of high-frequency microstimulation (HFMS) of one of the hemispheres on the parameters of spontaneous gamma-oscillations in the neural network containing callosal cells of the motor cortex of both hemispheres. Ther...
{ "pile_set_name": "PubMed Abstracts" }
11th GCC Closed Forum: cumulative stability; matrix stability; immunogenicity assays; laboratory manuals; biosimilars; chiral methods; hybrid LBA/LCMS assays; fit-for-purpose validation; China Food and Drug Administration bioanalytical method validation. The 11th Global CRO Council Closed Forum was held in Universal Ci...
{ "pile_set_name": "PubMed Abstracts" }
Assessment of in vivo CYP2D6 activity: differential sensitivity of commonly used probes to urine pH. Drug/metabolite ratios (MRs) are used as in vivo markers of enzyme activity. The ratios are potentially confounded by the renal clearance of the drug (urine-based MRs) or metabolite (plasma-based MRs). The authors have ...
{ "pile_set_name": "PubMed Abstracts" }
Molecular cloning of two novel protein kinase genes from Arabidopsis thaliana. We have isolated two novel protein kinase genes, MHK and NAK, from the plant Arabidopsis thaliana by using low stringency hybridization with the catalytic domain of a putative plant receptor protein kinase. Sequence analysis of the cDNAs rev...
{ "pile_set_name": "PubMed Abstracts" }
[Prevention of thrombo-embolic venous disease]. Large epidemiological studies have shown that nearly all risk factors for deep vein thromboses have a different impact on the manifestation of the disease, which aids in their differentiation into high, moderate and low risk. North American authors have introduced a fourt...
{ "pile_set_name": "PubMed Abstracts" }
[Respiratory muscle weakness after prolonged use of hydrocortisone and pancuronium bromide]. A 30-year-old man was admitted because of status asthmaticus. He required 7 days of artificial ventilation and was treated with hydrocortisone 1.2 g.day-1 and bronchodilaters. Pancuronium bromide 0.08 mg.kg-1.hr-1 was given for...
{ "pile_set_name": "PubMed Abstracts" }
Multi-level barriers to obtaining mammograms for women with mobility limitations: post workshop evaluation. To assess the barriers and facilitators to mammogram use in middle aged women with mobility limitations who had completed an educational workshop, Promoting Access to Health Service (PATHS), on clinical preventiv...
{ "pile_set_name": "PubMed Abstracts" }
Catecholamines in murine bone marrow derived mast cells. Cultured murine bone marrow derived mast cells (BMMC) were found to store high levels of dopamine (3753+/-844 pg/10(7) cells) and occasionally produce norepinephrine and epinephrine. The catecholamine synthesis inhibitor, alpha-methyl-para-tyrosine, decreased int...
{ "pile_set_name": "PubMed Abstracts" }
Temperature-induced fusion of small unilamellar vesicles formed from saturated long-chain lecithins and diheptanoylphosphatidylcholine. Small unilamellar vesicles which form when gel-state long-chain phosphatidylcholines are mixed with micellar short-chain lecithins undergo an increase in size as the long-chain species...
{ "pile_set_name": "PubMed Abstracts" }
Interaction between leukotriene D4 and adenosine or iloprost in the isolated working guinea-pig heart: prevention of the leukotriene D4 effect. The interaction between leukotriene D4 and adenosine or the prostacyclin analogue iloprost was studied in isolated guinea-pig hearts. Adenosine (1 X 10(-6) M) or iloprost (5 X ...
{ "pile_set_name": "PubMed Abstracts" }
Deficit versus negative syndrome in schizophrenia: prediction of attentional impairment. Findings on neuropsychological associates of the negative syndrome of schizophrenia have been inconsistent. The "deficit syndrome," a reconceptualization of the negative syndrome, was developed in part to address this inconsistency...
{ "pile_set_name": "PubMed Abstracts" }
Role of lecithin:cholesterol acyltransferase and apolipoprotein A-I in cholesterol esterification in lipoprotein-X in vitro. Lipoprotein-X (Lp-X) is an abnormal particle present in the plasma of patients with familial lecithin:cholesterol acyltransferase (LCAT) deficiency syndromes or cholestatic liver disease. Compare...
{ "pile_set_name": "PubMed Abstracts" }
Effect of a half dose of tamoxifen on proliferative activity in normal breast tissue. To investigate the proliferative activity of the mammary gland epithelium and plasma levels of progesterone, estradiol, prolactin, luteinizing hormone (LH), follicle-stimulating hormone (FSH) and sex hormone-binding globulin (SHBG) in...
{ "pile_set_name": "PubMed Abstracts" }
Detailed anatomy of penile neurovascular structures: surgical significance. In 10 formalin-preserved adult male cadavers, dissection of the penile veins, arteries and nerves revealed information of clinical importance. The main venous drainage of the corpora cavernosa is via the cavernous veins, with additional drainag...
{ "pile_set_name": "PubMed Abstracts" }
Peripheral conversion of L-5-hydroxytryptophan to serotonin induces drinking in rats. Female rats administered serotonin (0.25 to 4.0 mg/kg, s.c.) showed a dose-dependent increase in water intake. The dipsogenic response was nearly maximal when 2 mg/lg was administered s.c. and plateaued by 2 hr after treatment. l-5-Hy...
{ "pile_set_name": "PubMed Abstracts" }
Principles of burn dressings. Throughout history burn wounds have been treated by covering with dressings of many different materials. The successful application of a burn dressing remains an objective for biomaterial development. This paper examines how the burn wound differs from other skin injuries, the requirements...
{ "pile_set_name": "PubMed Abstracts" }
Propulsive force of Paramecium as revealed by the video centrifuge microscope. Using the video centrifuge microscope we constructed, we observed the behavior of Paramecium cells in a solution of graded densities under centrifugal acceleration. Beyond 300g, they not only gather in the zone where the density is closest t...
{ "pile_set_name": "PubMed Abstracts" }
Sensitive Determination of Cannabinoids in Whole Blood by LC-MS-MS After Rapid Removal of Phospholipids by Filtration. Direct analysis of Δ9-tetrahydrocannabinol (THC) and other cannabinoids in crude acetonitrile extracts of whole blood by liquid chromatography-tandem mass spectrometry using pneumatically assisted elec...
{ "pile_set_name": "PubMed Abstracts" }
Research ethics committees in Japan: A perspective from thirty years of experience at Tokushima University. The first Japanese ethics committee for biomedical research involving human subjects was established at Tokushima University in 1982. Although this committee was not formed as a response to national directives, t...
{ "pile_set_name": "PubMed Abstracts" }
Pure red cell aplasia. The so-called pure red cell aplasia or hypoplasia may occur in various instances: 1- Congenital form, usually occuring in childhood; 2-Drug-induced types; 3-The forms associated with thymoma, carcinoma and hypogamma-globulinemia; and 4-As an isolated syndrome. In the etiology of congenital PRCA s...
{ "pile_set_name": "PubMed Abstracts" }
The evolution of the vertebrate beta-globin gene promoter. Complexity analysis is capable of highlighting those gross evolutionary changes in gene promoter regions (loosely termed "promoter shuffling") that are undetectable by conventional DNA sequence alignment. Complexity analysis was therefore used here to identify ...
{ "pile_set_name": "PubMed Abstracts" }
Efficacy of mycophenolate mofetil on recurrent glomerulonephritis after renal transplantation. Recurrent glomerulonephritis in transplanted kidneys is not rare despite classical immunosuppressive drugs and depends on the etiology of nephropathy. Treatment of recurrence of renal disease on graft remains controversial. W...
{ "pile_set_name": "PubMed Abstracts" }
A missense mutation in a patient with guanosine triphosphate cyclohydrolase I deficiency missed in the newborn screening program. A patient with guanosine triphosphate cyclohydrolase I deficiency passed the newborn phenylketonuria screening program. The characteristic clinical phenotype developed in a 5-month-old patie...
{ "pile_set_name": "PubMed Abstracts" }
Analysis of VH gene rearrangement and somatic hypermutation in Sjogren's syndrome and IgG4-related sclerosing sialadenitis. IgG4-related sclerosing sialadenitis is currently considered as an autoimmune disease distinct from Sjogren's syndrome (SS) and responds extremely well to steroid therapy. To further elucidate the...
{ "pile_set_name": "PubMed Abstracts" }