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Introduction {#sec1-1}
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With the better understanding of the developmental neurobiology, it is now a well recognized fact that nervous system is sufficiently sensitive to nociception even before birth, and thus, children should not be undertreated for pain. This aspect has received considerable attention s... | {
"pile_set_name": "PubMed Central"
} |
The interstitial lung disease clinical nurse specialist {#s2}
=======================================================
Interstitial lung diseases (ILDs) are associated with fibrotic changes in the interstitium of the lung \[[@C1]\]. Whilst some forms of ILD are short lived, many are irreversible. ILDs are associated wi... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Most patients with acute pancreatitis (AP) present a mild course while 10%--20% of them develop severe disease with significant mortality \[[@B1]\]. Early prediction of disease severity of AP would be helpful for triaging patients to the appropriate level of care and interventio... | {
"pile_set_name": "PubMed Central"
} |
What's new?Current remote-monitoring technology in implantable devices enables the identification of patient-specific slopes of atrial electrical remodelling (AER) during atrial fibrillation (AF) progression.Time-to-completion of AER can be estimated using the computed patient-specific slope of atrial activation rate c... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
Classification of *Croton* and uses in ethnomedicine {#sec002}
----------------------------------------------------
*Croton* (Euphorbiaceae) is one of the largest genera of flowering plants, with between ... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
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The formation of amyloid is one of key characteristics in many neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's diseases. In these diseases, under particular conditions, structu... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
The Children with HIV Early Antiretroviral Therapy (CHER) study recently found that more infants randomized to deferring antiretroviral therapy (ART) until their CD4 fell below 25% died compared to those who started ART before the age of three months \[[@B1]\] but there is currently no randomized... | {
"pile_set_name": "PubMed Central"
} |
The elderly population has been growing for many years and is estimated to increase even more worldwide because of an increasing life expectancy. Therefore, organizations such as the World Health Organization (WHO) and the European Union have been articulating strategies focusing on promoting health globally among the ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s0001}
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The impact of visual impairment (VI) on the communication development in young children has been underestimated and undertreated (House & Davidson, [@CIT0022]; James & Stojanovik, [@CIT0023]). Underestimation and undertreatment may be because communication difficulties in children wi... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
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With modernization and advances in motorized technology, the pattern and problems associated with trauma are also changing. The 'floating knee' is one such injury, the incidence of which appears to be increasing. It is described as an ipsilateral concurrent break in the femur and ti... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Transfer RNA (tRNA) is an essential molecule used in protein biosynthesis by all living organisms. Maturation of tRNA involves many ribonucleases to correctly process the precursor tRNA into a functional form. In most Eukaryotes, precursor tRNAs are often interrupted by a short intron inserte... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S1}
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Crustaceans face a range of variable environmental stressors during their complex life cycle. Temperature and salinity are commonly considered as the most important abiotic factors for the survival, growth, and reproduction of crustaceans ([@B80]; [@B51]). However, ongoing ocean acidifi... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s01}
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To reach the cell surface, secreted proteins are transported along intracellular routes from the endoplasmic reticulum (ER) through the Golgi complex. Cargos exit the Golgi complex in transport carriers that use microtubules to be addressed rapidly to the plasma membrane before exocyto... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The complement system is part of innate immunity and is one of the major pathogenic event that drives various inflammatory responses in numerous diseases.^([@B1],[@B2])^ The complement system consists of three major pathways: the classical, mannose-binding lectin, and alternative pathways. Al... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Plantarflexion is achieved through the combined action of the soleus and gastrocnemius muscles, located in the calf \[[@B1], [@B2]\]. The gastrocnemius and soleus muscles share the Achilles tendon, the thickest and strongest human tendon, and are also known as the triceps surae ... | {
"pile_set_name": "PubMed Central"
} |
Aims and Scope
==============
*Annals of Clinical and Translational Neurology* is a peer-reviewed journal for rapid dissemination of high-quality research related to all areas of neurology. The journal publishes original research and scholarly reviews focused on the mechanisms and treatments of diseases of the nervous... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
The current therapeutic challenges in cancer, including chronic lymphocytic leukemia (CLL) the most prevalent leukemia of adults in the western world, involve the targeting of tumor-specific pathways in a more profound fashion than accomplished by conventional cytostatics \[[@CR1]\]. ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The palliative care, or comfort care, movement in the USA is on the rise ([@b1]). Over the last several years, hospitals have developed comfort and pain management programs that support minimizing pain and maximizing comfort for their patients. Accrediting institutions, such as the Joint Comm... | {
"pile_set_name": "PubMed Central"
} |
All software, data, and documentation are freely available under Apache v2.0 and Creative Commons licenses. All input, output, example, and evaluation data as well as reports and figures are publicly accessible from the Mindboggle Open Science Framework website (<https://osf.io/ydyxu/>). The Mindboggle-101 manually edi... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Otitis media (OM), inflammation of the middle ear, remains the most common cause of hearing impairment in children \[[@pgen-0020149-b001],[@pgen-0020149-b002]\]. Acute episodes of OM in infants and children are most often associated with middle ear infections involving the pathogens Str... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
A randomized, double-blind, placebo-controlled study was performed to evaluate the effect of adding protein (PRO) to a recovery mixture on exogenous and endogenous substrate oxidation during post-recovery exercise. Many studies have shown that carbohydrates (CHO) effectively restore glycogen post... | {
"pile_set_name": "PubMed Central"
} |
The authors confirm that all data underlying the findings are fully available without restriction. All data are included within the manuscript and Supporting Information files.
Introduction {#s1}
============
The Japanese traditional medicine (Kampo) daikenchuto (TU-100) has been established to have anti-inflammatory... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Glaucoma is a blinding optic neuropathy affecting nearly 60 million people world-wide. Among all forms of glaucoma, primary open angle glaucoma is the most frequent etiology \[[@CR1]\]. The therapeutic arsenal for primary open angle glaucoma includes pressure lowering medications, laser t... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Preterm premature rupture of membranes (PPROM), which is defined as spontaneous rupture of fetal membranes before labor begins before 37 weeks' gestation, affects approximately 3% of all pregnancies ([@ref1]). It is closely related with significant maternal and fetal morbidity and morta... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
Pathology diagnosis has been performed by a human pathologist observing the stained specimen on the slide glass using a microscope. In recent years, attempts have been made to capture the entire slide with a scanner and save it as a digital image (whole slide image, WSI) \[[@bb... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Short-chain fatty acids (SCFA, mainly acetate, propionate and *n*-butyrate) are produced during bacterial fermentation in the large intestine. Among these, *n*-butyrate (butyrate) in particular has attracted much attention because it is the major energy substrate for colonocytes and may... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#ece32120-sec-0001}
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Seasonal polyphenism is a phenomenon observed in species that respond to seasonally changing environmental parameters by expressing distinct phenotypes (Shapiro [1976](#ece32120-bib-0038){ref-type="ref"}; Simpson et al. 2011). The ability of environmental stimuli to deter... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Chronic lymphocytic leukemia (CLL) is the most frequent leukemia in Western countries and is characterized by a marked clinical, molecular, and prognostic heterogeneity \[[@B1]\]. While some patients without treatment have a life expectancy equal to that of the healthy populatio... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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INTRODUCTION
============
Attention deficit hyperactivity disorder (ADHD) is a clinical disorder characterized by persistent hyperactivity, inattention, and impulsivity.[@B1] Symptoms appear to be developmentally inappropriate and lead to functional impairments at home or in school.[@B2] Children with ADHD are more li... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
The breast is the most common site of primary malignancies in adult women, but is an uncommon site for metastasis from extramammary malignancies. The incidence of metastasis to the breast varies from 1.7 to 6.6% in autopsy series, due to the inclusion or exclusion of patients with leukemia or... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Intra-abdominal hemangiomas are rarely found outside of the liver \[[@R01]\]. Gastric haemangioma accounts for only 0.05% of all gastrointestinal (GI) neoplasms \[[@R02]\]. Isolated gastric hemangiomas generally manifest in routine clinical practice as epigastric pain and upper gastroin... | {
"pile_set_name": "PubMed Central"
} |
1 Introduction
==============
Since its introduction more than a century ago, random walks ([@btaa291-B63]) have been successfully applied to a wide range of sciences including Physics, Chemistry, Biology, Computer Science and Engineering. With its effective algorithmic layout, easy realization and efficiently produce... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1}
============
The Centers for Disease Control (CDC) projects that the proportion of adults older than 65 years of age in the US population will grow from 12.4 to 19.6% reflecting the aging baby boom generation and declining birth rates in the United States. Furthermore, the population of persons ol... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Traumatic cervical spinal injury is a common cause of severe disability. It is reported that about 11000 patients are admitted to hospitals due to cervical spinal injury annually[@B15] and around 75% of them require intubation and mechanical ventilation due to respiratory problems[@B21]. Trac... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Reactive oxygen species (ROS) are generated in the normal metabolism of living organisms, and besides of their useful role in signal transduction; they are also involved in the dispersion of several degenerative diseases like malignant tumors, rheumatic joint inflammation, cataracts, Parkinson's ... | {
"pile_set_name": "PubMed Central"
} |
Since Jacobs *et al*.[@b1] reported the first laparoscopic colectomy in 1991, the enthusiasm for mini-invasive surgery for colon cancer has been increasing every year[@b2]. A series of randomized, prospective clinical trials have confirmed that the oncologic outcomes of laparoscopic colectomy are equivalent to those of... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Malnutrition is responsible for about 24,000 deaths per day worldwide^[@CR1]^. Rice is staple food for more than half of the world population. It has a significant contribution in daily calorie-intake as millions of poor families depend mainly of rice for their nutrition. Rice supplie... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-pharmaceutics-07-00542}
===============
The field of genetics is the study of genes, inheritance and genetic variation, while genomics is the study of the complete DNA sequence in the genome. In recent years, genomics gave birth to a series of other omics that refer to the complete collection of... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
The Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disease of the neuromuscular transmission involving the presynaptic voltage-gated calcium channels (VGCCs) ([@b0040]). In most cases (60%), LEMS represents a paraneoplastic syndrome associated with small cell lun... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-18-00223}
===============
Just as the personal computer has revolutionized research in the sciences over recent decades, smartphones are now finding increasing application in a wide variety of research domains. This is expedited by the integrated data capture and processing capability (e... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Many carnivore species are currently threatened and are the focus of intense conservation concern [@pone.0024601-Baillie1]. Feline carnivores are often subject to illegal wildlife trade, thus the ability to estimate the geographic provenance of illegal tissue samples would constitute im... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Choledocholithiasis is the presence of gallstones in the common bile duct (CBD) and constitutes the dominating etiology of nonmalignant biliary obstruction \[[@b1-medscimonit-23-4500]\]. Choledocholithiasis develops in 8--20% of patients suffering from this common disorder, of which 5% are asympt... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Sharks are an important component of coral reefs, both in terms of the ecological role they play in reef ecosystems [@pone.0086682-Friedlander1]--[@pone.0086682-Sandin1], and increasingly because of their value for shark-diving tourism [@pone.0086682-Stoeckl1], [@pone.0086682-Vianna1]. ... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
The chemistry of ancient organic materials carries information of their original nature. Because this information is difficult to decode and limited by degradation, the depiction of chemical signatures preserved in the fossil record constitutes one of the essential challenges for paleontologi... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The bone extracellular matrix (ECM) has historically been described as a static and protective scaffold [@pone.0109078-Allori1]. Yet in reality, bone ECM is subjected to periodical remodeling to maintain its strength and integrity [@pone.0109078-Boyle1], [@pone.0109078-Rodan1]. The task... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
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"pile_set_name": "PubMed Central"
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Background {#Sec1}
==========
Osteoporotic hip fractures cause high mortality and morbidity in elderly adults \[[@CR1]--[@CR4]\]. One-year mortality rates after hip fracture were up to 30 % in the elderly \[[@CR1]--[@CR4]\]. After surgery for hip fractures in elderly patients, the short-term readmission or reoperation... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#gcbb12419-sec-0001}
============
*Miscanthus* is a bioenergy grass predominantly used for heat and power (Jensen *et al*., [2016](#gcbb12419-bib-0020){ref-type="ref"}). It is a perennial species that produces high annual yields and requires very low chemical inputs (Lewandowski *et al*., [2000](#gcbb124... | {
"pile_set_name": "PubMed Central"
} |
Please see related commentary by Balmelli *et al.*, <http://ccforum.com/content/15/2/131>
Introduction
============
N-terminal pro-brain natriuretic peptide (NT-proBNP) is the inactive polypeptide of the pre-prohormone brain natriuretic peptide (BNP). It is synthesized in the cardiac myocytes in response to hemodynam... | {
"pile_set_name": "PubMed Central"
} |
IN the course of this review, we will touch on many of the genes and processes conserved between mitosis and meiosis. Indeed, early studies in yeast and other fungi showed that mitotic recombination exhibited many of the same properties of meiotic recombination. For example, gene conversion, the nonreciprocal transfer ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
The industrial interest of carbon materials in any of their allotropic forms has considerably grown in the past century due to their interesting intrinsic physicochemical properties such as good electronic conductivity, high chemical stability, tailorable surface properties, eas... | {
"pile_set_name": "PubMed Central"
} |
**Pregnant women have long been orphaned from drug studies. The application of physiologically based pharmacokinetic modeling to quantitatively describe drug disposition and effects during pregnancy is an attractive approach that is now actively pursued as it allows optimal use of available information for both efficie... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
At a global level, amongst the most important groups of emerging infectious diseases are those caused by arboviruses. These include West Nile virus (North America, 1999), Rift Valley Fever virus (Arabia, 2000), and Chikungunya virus (Indian Ocean rim, 2005/2006; Italy, 2007) \[[@CR1], [@C... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Prostate cancer is an androgen-dependent disease that is well known for its high sensitivity to androgen deprivation. In fact, for over 50 years, the exclusive treatment of advanced metastatic prostate cancer was androgen deprivation achieved through castration, as it was believed that ... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
Introduction
============
Cell migration is a fundamental aspect in numerous normal and pathological processes, including embryonic development, wound healing, inflammation, and metastasis of tumor cells (for reviews see [Hay 1995](#Hay1995){ref-type="bib"}; [Viebahn 1995](#Viebahn1995){ref-type="bib"}; [Birchmeier et... | {
"pile_set_name": "PubMed Central"
} |
I.. INTRODUCTION {#acm20070-sec-0001}
================
Historically, it was expected that every inversely‐planned radiotherapy course would receive some level of experimental dosimetric quality assurance (QA) prior to first treatment.[^(1)^](#acm20070-bib-0001){ref-type="ref"} In the United States, such "patient‐speci... | {
"pile_set_name": "PubMed Central"
} |
Neurodegenerative diseases such as Alzheimer\'s disease, Parkinson\'s disease, and amyotrophic lateral sclerosis (ALS) are untreatable conditions that collectively represent a major healthcare burden. Improved understanding of the biology of these diseases is required in order to develop neuroprotective and ultimately ... | {
"pile_set_name": "PubMed Central"
} |
a**aambeeld (van het oor)**anvil, incus**aambeien**hemorrhoids, piles, varicose veins of anus**aambeien, extirpatie van \~**hemorrhoidectomy**aanbiedingsbrief**cover(ing) letter, transmission letter**aanbod van zuurstof**oxygen supply**aanbrengen op de huid**application on the skin N *(met name van zalf)***aandachtscon... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Influenza A virus still is a major cause of disease in humans, accounting for three to five million cases of severe illness and 250,000 - 500,000 deaths each year \[[@B1]\]. Efficient influenza A vaccines are available, which induce antibodies predominantly against the two major components of the... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION: THE PRIMARY CILIUM AS A COMPARTMENTALIZED ORGANELLE
=================================================================
The primary cilium is a tiny, antenna-like projection from the apical membrane of most vertebrate cells ([@B83]). Most cilia are a few micrometers in length and are ∼200 nm in diameter. L... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#section5-2042018820931664}
============
Laboratory glycated hemoglobin A1c (HbA1c) is a standard metric for the assessment of glycemic control in patients with diabetes mellitus. However, there are several limitations in the use of laboratory HbA1c for assessing glycemic control. Laboratory HbA1c could ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Diabetes Mellitus has emerged as a global burden, as World Health Organization (WHO) has estimated a prevalence of more than 300 million people by the year 2025. Diabetes is associated with a 2--4 fold increased risk for developing unstable angina and myocardial infarction (MI) ... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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(J Am Heart Assoc. 2019;8:e011721 DOI: 10.1161/JAHA.118.011721.)30879373
Clinical PerspectiveWhat Is New?This is the first study to systematically survey known dual certified physicians in both cardiovascular disease and critical care medicine.Dual certified physicians outlined which critical care skills were most rel... | {
"pile_set_name": "PubMed Central"
} |
**Suggested citation:** EFSA FEEDAP Panel (EFSA Panel on Additives and Products or Substances used in Animal Feed) , Bampidis V, Azimonti G, Bastos ML, Christensen H, Dusemund B, Kos Durjava M, Kouba M, López‐Alonso M, López Puente S, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F, Sanz Y, Villa RE, Woutersen R, Gropp... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Recently, there has been a growing movement away from the use of synthetic antioxidants and toward the use of natural antioxidants. This trend is thought to be due to the adverse effects of synthetic antioxidants like butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) on ... | {
"pile_set_name": "PubMed Central"
} |
**Session:** 250. HAI: *C. difficile* - Diagnostic Testing
*Saturday, October 5, 2019: 12:15 PM*
| {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Chronic kidney disease (CKD) is a well-known risk factor for cardiovascular disease and mortality.[@B1] CKD caused by nephrectomy may increase mortality by inducing cardiovascular disease; thus, to preserve kidney function, partial nephrectomy (PN) has become the standard surgical care for sm... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Although atherosclerosis is a systemic disease and the circulatory system is uniformly exposed to risk factors such as hyperglycemia and hypercholesterolemia, plaque development varies between vascular sites. For decades, clinicians have noted such heterogeneity of presentation,^[@b1]^ and re... | {
"pile_set_name": "PubMed Central"
} |
AbbreviationsATCCAmerican Type Culture CollectionBAYBAY 61‐3606Bsdblasticidine resistanceC+THP‐1 cells transduced with control (anti‐GFP) lentiviral particlesCD13cluster of differentiation 13CM‐H~2~DCFDA5‐(and 6‐)‐chloromethyl‐2′, 7′‐dichlorodihydrofluorescein diacetate acetyl esterCONACYTConsejo Nacional de Ciencia y ... | {
"pile_set_name": "PubMed Central"
} |
In the article titled "Topography Prediction of Helical Transmembrane Proteins by a New Modification of the Sliding Window Method" \[[@B1]\], the error occurred in formula (1): the summation index *i* of the function *f*~*n*~(*k* + *i*) was accidentally lost. It should be corrected as follows:$$\begin{matrix}
{f_{n}\le... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Autoimmune sialadenitis (AS) is characterized by chronic inflammation and swelling of the major or minor salivary glands (SGs), along with focal lymphocyte infiltration. In humans, AS is seen in primary Sjögren's syndrome (SS), and secondary SS associated with other autoimmune disease... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-19-04575}
===============
Flexible systems such as endoscopes are widely used for performing minimally invasive surgical interventions, as in intraluminal procedures or single port laparoscopy. Surgical platforms have been developed by companies and by laboratories to improve the capabil... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Obesity in children has become a serious public health problem similar to that found in the adult population. It is well known that obesity increases the risk of complications such as diabetes mellitus and cardiovascular disease in adults. Although obese children have lower incidences o... | {
"pile_set_name": "PubMed Central"
} |
Dr. Melissa Suh is not included in the author byline. She should be listed as the twelfth author and her affiliation is 1: Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska, United States of America. The contributions of this author are as follows: Data Curation, Methodology, Writing--Origin... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#S1}
============
Many babies are born preterm and despite improvements in their care, their extrauterine growth frequently falters ([@R1]--[@R3]). Although premature infants may be initially provided parenteral nutrition, the goal is to initiate and advance enteral feeding ([@R4]). However, enteral feed... | {
"pile_set_name": "PubMed Central"
} |
{#F1}
{#F2}
Eye injuries often occur in the workplace in low and middle-income countries, particularly in the construction, agricultural, mining, and manufacturing industries. Even if there are safety regulations in these industries, their enfor... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
Protein synthesis is an essential process undertaken by all organisms, but its necessity also presents cells with a myriad of challenges. An extensive network of molecular machines is active throughout tra... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction {#s2}
================
The log transformation, a widely used method to address skewed data, is one of the most popular transformations used in biomedical and psychosocial research. Due to its ease of use and popularity, the log transformation is included in most major statistical software packages inc... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
The discoveries of Interleukin-1 (IL-1) and IL-2 led to a better understanding of the effects of ILs, and till now more than 40 cytokines are discovered with specific functions \[[@B1]\]. Interleukin-4 (IL-4) is one of the extensively studied cytokines which induces specific fun... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-genes-10-00220}
===============
Microbial life is one of the most diverse and bioenergetically dominant forces in the earth's ecosphere \[[@B1-genes-10-00220]\], making microbiome research a critical component of modern ecology. The unparalleled taxonomic and functional diversity of microbial co... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Microtubules (MTs) are highly dynamic structures crucial for many cellular processes, such as cell division and cell polarity. MTs consist of α-β--tubulin heterodimer stacks ([@B51]) that generate a polarized structure. MT minus ends are usually stabilized at an MT-organizing center, whereas ... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
TEs and their abundant relics are found in the genome of almost all organisms and are classified into many distinct families based on sequence features and transposition mechanisms \[[@CR1]\]. DNA transposons generally exhibit cut-and-paste transposition, while retrotransposons use an RNA... | {
"pile_set_name": "PubMed Central"
} |
As the adoption of electronic health records (EHRs) has made it easier to access and aggregate clinical data, there has been growing interest in conducting research with data collected during the course of clinical care.[@b1] [@b2] The Natonal Institutes of Health has called for increasing the reuse of electronic recor... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-nutrients-09-01140}
===============
Early nutrition is crucially important for children to survive, grow and develop into healthy adults who can lead rewarding lives and productively contribute to their communities, and improving nutrition among young children has widely been recognized as an in... | {
"pile_set_name": "PubMed Central"
} |
Duchenne muscular dystrophy (DMD) is the commonest form of muscular dystrophy in humans^(^[@ref1]^)^ and it is inherited from a recessive X-linked gene, affecting 1 in 3500 newborn males^(^[@ref2]^)^. The disease involves progressive muscle degeneration until death at about 20 years of age, usually caused by cardioresp... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Treatment with immune checkpoint inhibitors (ICIs) has transformed the field of oncology, improving long-term survival in patients across several types of cancer.[@R1] The most commonly used ICIs target cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), programmed cell death protein ... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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1. Introduction {#sec1}
===============
Fetal infection following maternal varicella, especially during the first 20 weeks of gestation, can result in varicella embryopathy, also known as congenital varicella syndrome or fetal varicella syndrome. This constellation of malformations was first described by LaForet and L... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Engaged patients are research *partners*, involved in the planning, conduct and governance of health research, rather than serving as passive study subjects \[[@CR1]--[@CR3]\]. Patient engagement could improve the relevance of health research, facilitate the adoption of research findings ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s0001}
============
Anthrax is a severe infectious disease caused by a bacterium known as *Bacillus anthracis*. Anthrax can be found naturally in soil and commonly affects domesticated and wild herbivores. Although anthrax is perceived to be a weapon of bioterrorism in most countries in the world (Siamu... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper.
Introduction {#sec001}
============
Vascular smooth muscle cells (VSMCs) are essential regulators of vascular function \[[@pone.0170699.ref001],[@pone.0170699.ref002]\]. In healthy arteries, VSMCs are located in the medial vascular layer, where they express contractile proteins... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Free water in the context of neuroimaging refers to extracellular non-flowing water in the cranium and brain tissue. Quantifying free water is of interest for estimating cerebral spinal fluid (CSF) contamination and as an index measured within brain tissue since it is sensitive ... | {
"pile_set_name": "PubMed Central"
} |
Summary
=======
Neuroprolotherapy and acupuncture for clinical trial of acute and chronic migraine treatment.
Objectives
==========
Formulation of protocol for clinical trial of neuroprolotherapy and acupuncture treatment of migraine, partially based upon treatment sites used in OnabotulinumtoxinA treatment of migra... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Lipopolysaccharide (LPS), a glycolipid constituent of the outer membrane of Gram-negative bacteria, initiates inflammatory signaling cascades in cells, including monocytes, macrophages, dendritic cells, and endothelial cells, leading to the upregulation of cytokines, chemokines, and other inf... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-children-07-00046}
===============
Anxiety may be defined as the bodily response to a perception of danger. If it is exaggerated or overplayed in case of the perception of danger that influences functionality, it may lead to a disorder in the long term \[[@B1-children-07-00046]\]. Contrary to so... | {
"pile_set_name": "PubMed Central"
} |
All data are included within the paper.
Introduction {#sec001}
============
The majority of viral, bacterial, and parasitic infections occur at mucosal surfaces, thus developing effective mucosal vaccines would greatly decrease the burden of infectious diseases. This task has however been challenging, mainly due to t... | {
"pile_set_name": "PubMed Central"
} |
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