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Introduction {#Sec1}
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Coronary atherosclerosis (CAS) is a chronic and complicated metabolic disease, and is the pathogenesis of coronary heart disease (CHD). It is characterized by endothelial dysfunction and chronic inflammation that interact with metabolic changes to trigger, propagate and activate lesio... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Metabolic syndrome (MetS) is a cluster of metabolic abnormalities, including raised triglyceride levels, low high-density lipoprotein cholesterol levels, raised blood pressure, and raised glucose levels \[[@CR1]\]. Available evidences show that MetS is strongly increasing the risk of ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Insect colonies exhibit some of the most sophisticated social organizations in nature. The largest societies consist of thousands to millions of workers and are often characterized by elaborate systems of division of labor (reviewed in Beshers and Fewell, [@CR1]). This social complexi... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction {#s1}
================
Single nucleotide polymorphisms (SNPs) occur in 1% or more within the population \[[@RSOB170019C1]\]. Although these populations are identical in 99.5% at the DNA level \[[@RSOB170019C2]\], there are approximately 10 million SNPs in the human genome, indicating that they occur o... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
It is estimated that colorectal cancer is the third most frequently diagnosed cancer in males and the second in females [@B1]. In 2008, an estimated 12 million new cases of colorectal cancer were diagnosed, and approximately 608,700 people died from colorectal cancer [@B2]. In 2010, the death... | {
"pile_set_name": "PubMed Central"
} |
Lu Y, Pang X, Yang T. Microwave cooking increases sulforaphane level in broccoli. Food Sci Nutr. 2020;8:2052--2058. 10.1002/fsn3.1493
1. INTRODUCTION {#fsn31493-sec-0001}
===============
Broccoli contains a group of secondary metabolites called glucosinolates (GSL). The basic chemical structure of GSL is depicted in ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-nutrients-12-00075}
===============
Leukemias and lymphomas are the most commonly diagnosed types of childhood cancer worldwide \[[@B1-nutrients-12-00075]\], and are responsible for the most cancer deaths among children \[[@B1-nutrients-12-00075]\]. Thus, underutilized avenues of care must be ex... | {
"pile_set_name": "PubMed Central"
} |
Correction to: *Scientific Reports* <https://doi.org/10.1038/s41598-018-36573-z>, published online 21 December 2018
A Supplementary Information file containing the accession numbers for the uncultured clones was omitted from the original version of this Article. This has been corrected in the HTML and PDF version of t... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Foot ulcers are one of the most serious complications for diabetics (Burns and Jan, [@B1]). Previous studies have reported that impaired functionality of microcirculation can cause plantar tissue ischemia, and increase the incidence of foot lesions and ulcers (Wiernsperger, [@B30]; Jan ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Advanced engineered biosurfaces have to not only recognize but also modulate complex molecular biointerfacial processes occurring in biological microenvironments. The current biomimetic surface engineering strategies have been developed to create graded and adaptive synthetic bi... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1}
============
In Alzheimer's disease, the β-amyloid peptide Aβ assembles to form a multitude of soluble oligomers as well as insoluble fibrils.^[@ref1],[@ref2]^ The Aβ oligomers have emerged as neurotoxic agents that lead to neurodegeneration in Alzheimer's disease. The heterogeneity and metastabil... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
*Toxoplasma gondii* is a zoonotic protozoan parasite distributed worldwide and globally ranked fourth among food-borne parasites that pose a threat to public health ([@bb0085]). *Toxoplasma gondii* has a complex life cycle where felids are the only known definitive hosts ([@bb0... | {
"pile_set_name": "PubMed Central"
} |
*On March 18, 2019, this report was posted as an*MMWR*Early Release on the*MMWR*website (<https://www.cdc.gov/mmwr>).*
Introduction
============
Medical treatment has substantially improved the health, quality of life, and life expectancy of persons with HIV infection ([@R1]). The benefits of treatment are maximized ... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Identification of appropriate tumor antigens is the first and most important step in the successful development of antigen-specific immunotherapy. Cancer-testis antigens (CTAgs) are expressed in a broad range of human tumors, but their normal expression is restricted to immunologically ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Social cognition is the way in which individuals process, remember, and use information in social contexts to explain and predict how people behave ([@B22]). In the current study, two aspects of social cognition were examined: Theory of Mind (ToM) and Emotion Understanding (EU). ToM concerns ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S0001}
============
Phenolic compounds of plant origin integrate a large group of plant secondary metabolites with remarkably rich structural variations, and with a large variety of biological functions and activities. Functions are inherently involved in biochemical processes of the producing plant its... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s0005}
===============
Protein structure is determined by the interactions among the amino acids and with the environment, resulting in a stable 3D structure. In the folding process, a stable 3D conformation of the protein corresponds to a minimum of the Gibbs free energy (ΔG) of the protein-environm... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-19-03503}
===============
Human action recognition is an active research topic with several applications in surveillance and security \[[@B1-sensors-19-03503]\], healthcare and assisted living \[[@B2-sensors-19-03503],[@B3-sensors-19-03503]\], and human--computer interaction \[[@B4-senso... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Leishmaniasis is a disease caused by protozoan parasites of the genus*Leishmania* and transmitted by the bite of infected female phlebotomine sandflies. The disease can be seen in three forms: cutaneous, mucocutaneous, and visceral leishmaniasis \[[@B1]--[@B3]\]. Leishmaniasis i... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Cardiogenic shock (CS) represents the leading cause of death in patients hospitalized with acute myocardial infarction (AMI) \[[@CR1]-[@CR3]\]. Despite advances in treatment over the last decades, mortality rates are still approaching 50%. The pathophysiology of CS is characterized by... | {
"pile_set_name": "PubMed Central"
} |
<https://dhsprogram.com/data/available-datasets.cfm>.
Introduction {#sec001}
============
In recent years, modelling of count response data is of primary interest in many fields such as public health, epidemiology and demography. Poisson regression (PR) is commonly used as the base or standard model for the analysis ... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
The Great East Japan Earthquake that occurred on 11 March 2011 and the Fukushima Daiichi nuclear disaster forced people to evacuate their hometowns with notice, caused them to change their lifestyle to fit a completely new situation, and produced anxiety about radiation. In response to co... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Anterior knee pain (AKP) is "a common symptom complex typically characterized by diffuse retropatellar or peripatellar knee pain exacerbated by activities that load the flexed knee joint"[@r1]^)^. Such activities include ascending or descending stairs, squatting, walking, running, or si... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Brain tissue is anatomically composed of 3 compartments: neural cells, vascular system, and brain extracellular space (ECS). Although neural cells have long been considered as the most important functional element of the brain, they only occupy 70--80% of the total brain volume \[[@b1-medscimonit... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Osteoarthritis (OA) is the most common form of arthritis, involving approximately 10% of Canadians \[[@B1]\]. The disease is characterised by disruption of chondrocyte homeostasis with the balance being shifted toward tissue degradation, leading to the progressive loss of cartilage extracellu... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Protein subcellular localization requires tight and timely regulation, to ensure proper environment and interaction partners, and ultimately function \[[@CR1]\]. Localization regulation is achieved through diverse mechanisms which can act sequentially, combinatorially or competitively, th... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Hepatocellular carcinoma (HCC), the fourth leading cause of all cancer-related deaths worldwide, accounts for 90% of all primary liver malignancies \[[@r1]\], the major attributable factors of which are chronic hepatitis B or C virus infection and the abuse of alcohol \[[@r2]\].
Current anti... | {
"pile_set_name": "PubMed Central"
} |
**Correction to:** *British Journal of Cancer* (2006) **95**, 401--405, doi:10.1038/sj.bjc.6603246
Owing to an author error, there was an erroneous statement presented in the Abstract of the above paper.
Where it was stated, 'Assuming average lead times of 5 to 10 years, 40--64% of the PSA-detected cases were estimat... | {
"pile_set_name": "PubMed Central"
} |
The editorial team is grateful to all the experts who dedicated their time to peer-review our articles over the past 12 months. We wish to thank them and all those whose names are not listed below but gave helpful advice and support. We apologise to any reviewers whose names we may have missed.
Our reviewers in 2017 w... | {
"pile_set_name": "PubMed Central"
} |
Genotypes of all individuals from the 30 populations included are available from the Dryad database (accession number doi:[10.5061/dryad.dh38n](http://dx.doi.org/10.5061/dryad.dh38n)).
Introduction {#sec001}
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The Biological Species Concept defines species as reproductively isolated units \[[@pone.0161266.... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
In vertebrates, melatonin serves as a hormonal signal of night, and consequently, as a signal of the night\'s duration through the changing seasons. In a number of mammalian species, the duration of the nocturnal melatonin elevation regulates seasonal changes in reproductive hormones such as lute... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
Introduction
============
Granuloma formation is a hallmark of *Mycobacterium tuberculosis* (*Mtb*) infection and represents the histological correlate of inflammatory tissue responses generally associated with protective immunity \[1,2\]. Disease develops when an initial granulomatous focus cannot fully contain mycob... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Liver transplant recipients are at risk of a number of metabolic complications including new-onset diabetes mellitus, hypertension, hyperlipidemia, and vascular disease. Many of these complications are caused or exacerbated by immunosuppression. As graft survival has improved, t... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Child growth monitoring is aimed at improving and maintaining child health and nutrition \[[@CR1]\]. It is so far the best strategy carried out worldwide to tackle malnutrition \[[@CR2]\]. It involves regular measurement and plotting of a child's weight on a growth chart \[[@CR3], [@C... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Human pluripotent stem cells (hPSCs), including human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), can be differentiated into all cell types of the human body and have been applied in regenerative medicine and the pathophysiological analysis of intractab... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
Secondary forests comprise woody vegetation that recovers naturally after a complete anthropogenic forest clearance \[[@pone.0152596.ref001], [@pone.0152596.ref002]\]. They are valuable remnants as they ar... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The amygdala, an important structure within the limbic forebrain, interacts with both the cortex and the striatum to influence motivated behavior. The amygdala itself has long been associated with emotional processing, particularly the emotion of fear. Monkeys with amygdala damage are t... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-20-01826}
===============
Atomic magnetometers have been used in a wide range of applications to detect weak magnetic fields, such as magnetoencephalography (MEG) \[[@B1-sensors-20-01826],[@B2-sensors-20-01826],[@B3-sensors-20-01826]\], magnetocardiography (MCG) \[[@B4-sensors-20-01826],... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The prevalence of diabetes mellitus (DM) is increasing each year. The International Diabetes Federation has estimated that 415 million people have been diagnosed with DM worldwide and anticipates an increase of up to 640 million by 2040 ([@b1-etm-0-0-7383]). Diabetic neuropathy (DN) is one of... | {
"pile_set_name": "PubMed Central"
} |
All protein structure files are available from the PDB database (accession code 5TJF).
Introduction {#sec001}
============
Aquatic organisms, such as cyanobacteria, eukaryotic red alga and cryptophyta, present accessory light harvesting protein complexes called phycobilisomes (PBS) \[[@pone.0177540.ref001]\]. The str... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Immunoglobulin (Ig)A antibodies (Abs) are a first line of immune protection for many viral infections at mucosal surfaces. The mechanisms by which mucosal IgA is induced and how innate immune recognition of pathogenic microorganisms have a role in Ig class switch recombination are an area of ... | {
"pile_set_name": "PubMed Central"
} |
I[NTRODUCTION]{.smallcaps} {#sec1-1}
==========================
Protease-activated receptors (PARs) are a family of G-proteincoupled receptors activated by site-specific proteolytic cleavage of a "tethered ligand" or PAR-activating peptide (PAR-AP).\[[@ref1]\] Four members of this family have been identified to date,... | {
"pile_set_name": "PubMed Central"
} |
BACKGROUND {#sec1-1}
==========
The remnants of India\'s colonial past are carried today in systems that have styled inequities that create a clear health burden for some Indian citizens. European hegemony has long ended and a global world of communication, evidence, and a deeper understanding of the interaction of ou... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
Working in a stressful setting such as intensive care unit (ICU) may have detrimental effects on nurses' psychological health. "Post mortem care, seeing patients die, involvement with end-of-life care, ope... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Non-alcoholic fatty liver disease (NAFLD) is one of the increasing metabolic disorders which has a direct link with obesity, glucose intolerance, inflammatory pathways and dyslipidemia.^[@R1]^ Fatty liver disease refers to a wide range of liver damages, ranging from plain steatosis to s... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
*Megalictis ferox* Matthew, 1907 \[[@pone.0152430.ref001]\] is a giant mustelid of the subfamily Oligobuninae and belongs to the paraphyletic group of "paleomustelids" \[[@pone.0152430.ref002]\]. It lived ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
The search for new energy systems based on renewable sources which require less energy consumption and are more environmentally friendly draws more and more attention. Over the past years, significant emphasis has been put on the development and understanding of light-driven charge sepa... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S0001}
============
Phototherapy is usually a part of the total treatment plan for the management of patients with atopic dermatitis (AD) \[[@CIT0001], [@CIT0002]\]. Ultraviolet A1 (UVA1) is effective in managing flares, whereas narrow-band UVB has been recommended for chronic moderate forms of the dise... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The morbidity of pancreatic cancer has been increased globally in recent years. Moreover, the prognosis of pancreatic cancer is very poor. With the development of research in molecular biology, oncology and the related subjects, the gene therapy of pancreatic cancer is regarded as a new mode ... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
A sedentary lifestyle is known to be a major cardiovascular risk factor predisposing individuals to cardiac events such as myocardial infarction (MI) ([@b1-cln_68p549]), which is the most common etiology of heart failure (HF). In recent years, studies have provided strong evidence for the ben... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Few studies have been published regarding attention deficit and hyperactivity disorder (ADHD) and child development in aboriginal children, and none of them has discussed autism spectrum disorder (ASD) in aboriginal children. The Australian longitudinal birth cohort study of urban aboriginal ... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper and its Supporting Information files.
Introduction {#sec001}
============
Verticillium wilt, a devastating disease of more than 200 crops worldwide, is typically caused by the soil-borne fungus *Verticillium dahliae* \[[@pone.0153988.ref001]\]. *V*. *dahliae* secretes various ef... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
H~2~ energy has drawn attention as an alternative energy source^[@CR1],\ [@CR2]^. Currently, the annual production of H~2~ is approximately 0.1 Gtons, of which 98% comes from the reforming of fossil fuels^[@CR3]^: 40% of H~2~ is produced from natural gas, 30% is produced from heavy oi... | {
"pile_set_name": "PubMed Central"
} |
**Background:** During the seasons 2013--2014 and 2014--2015 10 cities of Russia were involved into sentinel surveillance (SS). SS hospitals and laboratories were located in 6 Federal Districts (FDs) of Russia.
**Methods:** The investigations were conducted at 19 hospitals reporting weekly data on severe acute respira... | {
"pile_set_name": "PubMed Central"
} |
The purine ribonucleoside adenosine is an endogenous modulator of brain function uniquely positioned to integrate a wide variety of signalling pathways. Due to its early evolutionary roots -- adenosine was already part of the "RNA-world" and strategically placed to bridge cellular activities (as building block of nucle... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Chlorophyll (Chl) is the abundant pigment involved in the sunlight absorption of photosynthesis, and is annually broken down into more than 10 billion tons in nature. Chl biosynthesis and degradation are regulated by plant development, the environment, and stress response. Chlorophyllas... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Recently, smart surfaces with switchable wettability have attracted broad interest because they can selectively exhibit different and even inversed superwetting states.^[@ref1]−[@ref4]^ Such materials can reversibly switch their static and dynamic wettabilities by responding to ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Growth rates of tropical tree species vary widely between species and in response to resource availability (e.g. light, soil moisture, nutrients) and individual condition (e.g. size, vigor) [@pone.0025330-Dalling1], [@pone.0025330-Herault1]. Tree growth is an important component of demo... | {
"pile_set_name": "PubMed Central"
} |
Hypertension is a well-recognized risk factor for cardiovascular and renal diseases; moreover, even slightly elevated blood pressure (BP) levels lead to increased risk in cardiovascular diseases (CVD) or stroke.^[@R1]^ Hence, it is one of the leading causes of global burden of disease.^[@R2]^ As age is an important ris... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Fatigue is common after stroke, with estimates of prevalence ranging from 16% [@pone.0016988-Glader1] to 70% [@pone.0016988-Leegard1]. Fatigue is one of the most distressing symptoms after stroke [@pone.0016988-vander1], yet its aetiology remains uncertain. In the general non-stroke pop... | {
"pile_set_name": "PubMed Central"
} |
Symptoms of disordered eating are common among patients seeking bariatric surgery, and assessment of eating pathology is typical in pre-surgical evaluations. This systematic review evaluates the methods used to assess disordered eating in bariatric surgery candidates. A systematic literature search of papers published ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-1}
============
Meningiomas in children are a rare occurrence. They comprise approximately 3% of all pediatric brain tumors.\[[@ref1]\] Primary intraventricular meningiomas (IVMs) are even rarer with reported incidence of 0.5%--5% of all meningiomas. IVM arise from arachnoid cap cells embedded in c... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
In case-control studies, the search for disease-causing variants is typically focused on those single base substitutions that bring about a direct change in the primary sequence of a protein (that is, missense variants), the consequence of which may be structural or functional changes to the ... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Nonmonogamy is part of the evolutionary trends preserved in humans \[[@B1]\]. In fact, infidelity constitutes probably one of the most complex problems faced by mental health professionals, especially couple therapists, marriage and family therapists, and psychotherapists \[[@B2... | {
"pile_set_name": "PubMed Central"
} |
LETTERS TO EDITORS
==================
We have read with curiosity a recently published article in *The Korean Journal of Pain* by Kim and Abdi \[[@B1]\], entitled \"Rediscovery of nefopam for the treatment of neuropathic pain\". The authors skillfully reviewed the literature on nefopam\'s clinical applications, its me... | {
"pile_set_name": "PubMed Central"
} |
In mammals, the approximate 24 h oscillation of the circadian clock is critical for maintaining metabolic homoeostasis. A pacemaker in the suprachiasmatic nucleus (SCN) of the hypothalamus functions as a central clock to lead an orchestra of individual rhythms in peripheral tissues[@b1]. However, this dominance of the ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
There is increased attention toward using degradable, renewable films and coatings from polysaccharide, protein, and lipid biopolymers. Natural biopolymer-based packaging materials have great prospective for extending food quality and safety as an innovative packaging and processing technolog... | {
"pile_set_name": "PubMed Central"
} |
*\'So Hiraa where are you from?\'*
*\'I\'m from Manchester\'*
*\'No, where are you actually from?\'*
*\'Oh well actually, I\'m from Rochdale.\'*
*\'No I mean what are you?\'*
In response to those questions, I\'ve recently qualified as a Dentist from Birmingham and I\'m from a small town called Rochdale, but what a... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Interleukin-9 (IL-9) was at first characterised as a growth factor for mast cells and T cells ([@ref13]). Although the primary source of IL-9 is a subset of T lymphocytes called Th9, the other T cells subsets such as Th2, Th17, or Treg also can express IL-9 ([@ref6]; [@ref13]). IL-9 productio... | {
"pile_set_name": "PubMed Central"
} |
Peptidoglycan (Pg) Structure in Neisseria
=========================================
The pathogenic Neisseria attracted the attention of peptidoglycan (PG) researchers due to the propensity of these bacteria to release small PG fragments during growth ([@B76]; [@B87]). During gonococcal infections, these released PG fr... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Artificial intelligence (AI) has become a topic of central importance to the ways in which health care will change in the coming decades, with recent commentaries addressing potential transformations in clinical care \[[@ref1],[@ref2]\], public health \[[@ref3]\], and health system planning \... | {
"pile_set_name": "PubMed Central"
} |
(To access the full article, please see PDF)
| {
"pile_set_name": "PubMed Central"
} |
Plain English Summary {#Sec1}
=====================
In Bangladesh, total fertility rate (TFR) is high and at a static level for the last two decades. Increasing use of contraceptives could reduce maternal and neonatal mortality. Within this country, the contraceptives prevalence rate (CPR) is lowest and TFR is highest... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Hartig \[[@B21]\] confirmed that wood discoloration was caused by a dark mycelial fungus. It was the start of wood stain fungi research. Since then, a large number of studies on stain fungi had been carried out. The molds caused sapstain of pine, kumquat, grapevine,*Abies balsam... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Attention-deficit/hyperactivity disorder (ADHD) is a neuropsychiatric disorder which is typified by developmentally inappropriate symptoms of inattention, impulsivity, and hyperactivity, that are present in various surroundings (e.g., school and home), leading to deficits in social, education... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
The usual signs and symptoms of organophosphate (OP) poisoning are characterized by muscarinic, nicotinic, and central nervous system effects, and those of pyrethrin poisoning depend on the type of pyrethrin ingested. Pyrethrins are strongly lipophilic esters; short-term exposure ca... | {
"pile_set_name": "PubMed Central"
} |
10.1093/infdis/jiu488
[To the Editor]{.smallcaps}---In response to our recent article on sex differences in pediatric infectious diseases \[[@JIU489C1]\], Eisenhut \[[@JIU489C2]\] highlighted the role of nucleotide binding oligomerization domain receptor 2 (NOD2) in the nonspecific (heterologous) effects of BCG immuni... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Many scientists view nanotechnology as the revolutionary technology of the twenty-first century because it opened new possibilities for improvement of products used in healthcare, cosmetics, and medicine. Nano-sized materials, on the other hand, can also have negative effects on human hea... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#s001}
===============
E[nceladus is an icy moon]{.smallcaps} of Saturn with surface features that range in age from old cratered terrains that formed 4.2--4.6 Ga (Porco *et al.*, [@B46]; Kirchoff and Schenk, [@B27]) to the south polar terrain (SPT) dominated by prominent tiger stripe troughs that may... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-molecules-22-00119}
===============
The 2015 Nobel Prize in physiology and medicine awarded to the Chinese scientist Youyou Tu, for her discoveries concerning a novel therapy against malaria \[[@B1-molecules-22-00119],[@B2-molecules-22-00119]\], honored a lifelong work in structure elucidation a... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Iron (Fe) is an essential micronutrient in biological systems and plays an important role in several cellular processes, such as adenosine triphosphate (ATP), deoxyribonucleic acid (DNA), and neurotransmitter synthesis.\[[@ref1][@ref2]\] Tissue iron is stored inside a porous protein... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .208}
| {
"pile_set_name": "PubMed Central"
} |
Essential Points
================
- Medroxyprogesterone acetate (MPA) is an outlier amongst progestins, acting via the glucocorticoid receptor (GR) and exhibiting relatively potent glucocorticoid-like effects similar to cortisol, unlike norethisterone (NET) and levonorgestrel (LNG) and luteal phase progesterone
- ... | {
"pile_set_name": "PubMed Central"
} |
(To access the full article, please see PDF)
| {
"pile_set_name": "PubMed Central"
} |
Background
==========
Preclinical models of articular cartilage repair are of paramount importance to translate experimental approaches into the clinical situation \[[@B1]\]. The sheep or goat stifle joint is one preferred model for those studies \[[@B2]-[@B4]\] as it combines unique advantages over other species, suc... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S1}
============
Psychosocial adjustment of people with mental disorders is severely diminished, in particular, they live 10 years less than the general population ([@B63]), with a lower quality of life ([@B2]; [@B21]) and a higher level of disability ([@B2]). To manage these disorders, the emphasis is ... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Individual identification is gaining importance like never before in the present world. Numerous methods have been used for personal identification in forensic odontology, which include rugoscopy, cheiloscopy, bite marks, tooth prints (ameloglyphics), radiographs, photographic study... | {
"pile_set_name": "PubMed Central"
} |
**Learning Point for this Article:**
Coxa vara in polyostotic fibrous dysplasia can be easily managed by appropriately timed valgus osteotomy to prevent pathological fracture.
Introduction {#sec1-1}
============
The term "Fibrous Dysplasia" was given by Lichtenstein in 1938 \[[@ref1]\]. Fibrous dysplasia is a rarebe... | {
"pile_set_name": "PubMed Central"
} |
1 Introduction
==============
Important roles are emerging for local DNA structures in the regulation of basic biological processes ([@btz087-B2]; [@btz087-B19]). Sequences that can form G-quadruplex (G4) structures are widespread in a variety of genomes ([@btz087-B13]; [@btz087-B15]; [@btz087-B18]). G4 structures oft... | {
"pile_set_name": "PubMed Central"
} |
Equine coronavirus (ECoV) has been identified by electron microscopy, culture and more recently by PCR in feces of foals with and without enteric disease. A recent study reported on the isolation of ECoV from the feces of 2- to 4-year-old horses with pyrogenic and enteric disease living in stables of a racetrack in Jap... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .285}
{#sp2 .286}
| {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
BMP/RA-inducible neural-specific protein(s) (*Brinps*) are a family of three highly conserved vertebrate genes that are almost exclusively expressed in neurons in the central and peripheral nervous system (Kawano et al., [@B15]; Terashima et al., [@B25]). They form part of a larger prot... | {
"pile_set_name": "PubMed Central"
} |
1. Terminology of Tendon Diseases {#sec1-ijms-21-00844}
=================================
Tendon disorders have become very common in today's athletic and non-athletic population and account for a substantial proportion of activity-related diseases of the musculoskeletal system. Due to the increasingly aged demographi... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Two distinct heart fields, the FHF (first heart field) and the SHF (second heart field), are derived from anterior lateral plate mesoderm and splanchnic mesoderm, respectively. In the mouse embryo, the FHF forms a crescent shape at E7.5, and the cells coalesce along the ventral midline ... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s0001}
============
The Norwegian Coordination Reform (CR) has been gradually implemented in the period 2012 to 2016, but financial, juridical, organizational and professional measures were first presented in a national healthcare plan in 2010 \[[@C1]\]. The reform aimed at increasing the proportion of ... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
The role of any classification is to highlight the essential and defining element in a group of related phenomena, in order to facilitate some practical decision making. The major difficulty encountered in medical science is to find a criterion that can frame all forms of sickness in a cohere... | {
"pile_set_name": "PubMed Central"
} |
Relevant data are within the paper and its Supporting Information files. Additionally, cheetah camera trap data are available on Figshare at <http://dx.doi.org/10.6084/m9.figshare.1609865>.
Introduction {#sec001}
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Many large African carnivores have disappeared from their historical ranges due to habitat f... | {
"pile_set_name": "PubMed Central"
} |
{#sp1 .519}
{#sp2 .520}
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"pile_set_name": "PubMed Central"
} |
Introduction
============
Primary liver cancer is one of the most common malignant tumors, with the fifth highest incidence and third highest mortality rate of all malignancies worldwide.[@b1-ijn-8-1517],[@b2-ijn-8-1517] The incidence of liver cancer in the People's Republic of China accounts for about 55% of the glob... | {
"pile_set_name": "PubMed Central"
} |
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