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Introduction
============
Obstructive sleep apnea (OSA) is a chronic disease that influences several systems *in vivo*. It is characterized by the obstruction of the upper airways with repetitive pauses in breathing during sleep (despite efforts to breathe) as well as by daytime sleepiness ([@B01]). OSA affects at lea... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Hypertension is present in 71--95% of adult patients with chronic kidney disease (CKD) [@pone.0084848-Parikh1]--[@pone.0084848-Sarafidis1]. High blood pressure (BP) is a major risk factor for cardiovascular morbidity and mortality [@pone.0084848-Sarnak1] and is associated with an increa... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The progressive increase in the global area and number of GM crops has lead to numerous empirical studies on transgene flow in field trials aimed at developing containment strategies, which are required by regulators and policy makers to legislate, on a case-by-case basis, how deliberat... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Delineating a set of essential genomic elements and proteins that make up a living organism helps to understand critical cellular processes that sustain life ([@gkt1131-B1]). Identification of essential genes is especially useful to studies of synthetic biology ([@gkt1131-B4]), which seeks to... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijms-17-00900}
===============
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic synovial inflammation. Small joints of the hands and feet are more frequently affected; however, this varies with each individual. RA affects about 0.5%--1% of the population \[[@B1-ijms-1... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
There are more than 35,000 new oral and pharyngeal cancers (OPCs) diagnosed each year in the USA \[[@CR1]\]. This represents an increase during the past few years. While tongue is the most common site, malignancies of the tonsillar region are increasing. Unfortunately, in-spite of adv... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Bloodworms are a group of bristle worms found at the bottom of marine waters. They have pale skin, which allows their red body fluid, which contains hemoglobin, to show through, hence the name "bloodworm". Bloodworms are often used as bait in fishing and are also available commercially as a f... | {
"pile_set_name": "PubMed Central"
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Introduction
============
Cardiovascular disease, including atherosclerosis, stroke, and MI, is the leading cause of death in the world ([@B10]). In 2015, CVD accounted for one-third of all deaths, and there was an estimated 422.7 million cases of CVD and 17.92 million CVD-related deaths ([@B54]). Ischemic heart disea... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Carbapenemase-producing *Enterobacteriaceae* have become a challenge to clinical therapy because of the rapid worldwide dissemination of multi-drug resistance ([@B19]). Among the newly emerged carbapenemases, New Delhi metallo-β-lactamase-1 (NDM-1)-producing strains, which are capable of hydr... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Autobiographical memories (AMs) are recollections of the first-person experience of past episodes. They refer to spatially and temporally specific events rather than factual (semantic) knowledge about the world [@pone.0044809-Manns1]--[@pone.0044809-VarghaKhadem1]. From the neuropsychol... | {
"pile_set_name": "PubMed Central"
} |
The cavities beneath Antarctic ice shelves are among the least sampled components of the climate system. Yet, ice shelf retreat is today the leading driver of change in the grounded Antarctic ice sheet, and ocean forcing is, in turn, an important driver of change in ice shelves ([@r1], [@r2]). Ice shelf basal melting i... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
It has been 2 months since reports began to appear in the medical literature and on social media discussing the appearance of chilblain like lesions on the toes of children and young adults \[[@CR1], [@CR2]\]. The phenomenon received a lot of coverage in the media - at a time when availab... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#section1-0042098017730520}
============
Wealth inequality, as a separate dimension of socio-economic stratification, has recently attracted much scholarly attention ([@bibr33-0042098017730520]). Although housing wealth is the largest component of wealth for the majority of households, only a few studies... | {
"pile_set_name": "PubMed Central"
} |
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1. Introduction
===============
Marine sponges of the genus *Acanthella* have proven to be a rich source of new diterpenes and sesquiterpenes containing nitrogenous functional groups, including isonitrile (--NC), isothiocyanate (--NCS), isocyanate (--NCO), and formamide (--NHCHO) functionalities, which show various pr... | {
"pile_set_name": "PubMed Central"
} |
European health systems have increasingly come under pressure to implement cost-containment measures while simultaneously maintaining or even enhancing high-quality health care. In the field of medication of minor ailments, a promising approach to achieve this is initiatives promoting patient involvement (i.e. self-car... | {
"pile_set_name": "PubMed Central"
} |
###### Key questions
What is already known?
======================
- HIV-exposed children in resource-limited settings face multiple and complex stressors associated directly and indirectly with HIV infection.
- Early interventions for HIV-exposed children have led to documented improvements in child outcomes in... | {
"pile_set_name": "PubMed Central"
} |
Related literature {#sec1}
====================
For a related structure, see: Jamal *et al.* (2011[@bb3]). For background to Schiff bases, see: Chaluvaraju & Zaranappa (2011[@bb2]); Khan *et al.* (2009[@bb4]).
Experimental {#sec2}
==============
{#sec2.1}
### Crystal data {#sec2.1.1}
C~16~H~15~N~3~O*M* *~r~... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Cardiovascular disease (CVD) has been a major cause of death around the world \[[@CR1]\]. Although CVD mortality has decreased in developed countries in recent decades \[[@CR1]\], CVD accounts for 46 % of total deaths in Europe \[[@CR2]\] and creates high socioeconomic burdens, costing up... | {
"pile_set_name": "PubMed Central"
} |
Nature Communications 8: Article number: 15840; DOI: 10.1038/ncomms15840 (2017); Published 06 15 2017; Updated 11 29 2017
In this Article, two papers are mistakenly listed as having made use of the antibody 14C8 instead of the antibody PPG5/10. In the Discussion section, ref. 45 is incorrectly cited as having shown th... | {
"pile_set_name": "PubMed Central"
} |
Epidemiology of pulmonary complications in patients with haematological malignancies {#bjh13934-sec-0001}
====================================================================================
Respiratory symptoms or signs such as dyspnoea, cough, sputum, chest pain, rales, haemoptysis, impaired oxygenation and/or pulmo... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Visualization is an essential aspect of the statistical analysis of large-scale genomic data collections. It plays important roles in exploring, analyzing, and presenting patterns and correlations found in multidimensional genomic data.[@b1-cin-13-2014-013] The circular plot with multiple "do... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#S1}
============
Since 1980, the prevalence of obesity among children and adolescents has almost tripled. Current estimates suggest that approximately 17% of children 2--19 years of age are obese. This percentage equates to 12.7 million children in the United States ([@B1]). These data are more striking... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has become the procedure of choice to obtain samples to reach the definitive diagnosis of lesions of the gastrointestinal (GI) tract and of adjacent organs.\[[@ref1]\] EUS-FNA is safe and very accurate, especially when ra... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Betaine (trimethylglycine, glycine betaine, lycine, or oxyneurine) is a zwitterionic quaternary ammonium compound, discovered in the nineteenth century in the juice of sugar beets. Since betaine is characterized by a pKa value of 2.33 \[[@CR1]\] (Fig. [1](#Fig1){ref-type="fig"}), at e... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-biomolecules-10-00454}
===============
Recognizing the features of small, drug-like ligand molecules and protein structures that synergize to create an active protein state (binding to an agonist ligand) versus an inactive protein state (binding an inhibitory ligand) is essential to design drugs... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#S1}
============
Increasing evidence suggests that nuclear processes such as transcription, recombination, and repair can be influenced not only by local chromatin structure but also by three-dimensional (3D) genome architecture. Genomes of higher eukaryotes are compartmentalized into discrete structura... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Osteoporosis is a common skeletal system disease characterized by bone density attenuation and normal bone microstructure deterioration. All these changes can lead to an increased risk of fracture \[[@CR1]\]. Many of these fractures are related to increased morbidity and mortality seen in... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
The seed plays an important role in the transfer of genetic characters and improvement of qualitative and quantitative traits of production. One of the most important factors in maximizing crop yield is planting a high-quality seed. Seed size is an important physical indicator o... | {
"pile_set_name": "PubMed Central"
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"pile_set_name": "PubMed Central"
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Introduction
============
The total proteins in cereal grains mainly consist of grain storage proteins (SPs) and metabolic proteins. In wheat, SPs gliadins and glutenins, make up 60--80% of the total protein content. Glutenins are classified as high-molecular-weight or low-molecular-weight glutenin subunits (HMW-GS an... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Despite knowledge of the negative impact of environmental tobacco smoke (ETS) exposure on non-smokers\' health \[[@B1]\], children are still being exposed to ETS, most often by their parents \[[@B2]\]. The adverse impact of ETS exposure on the health of children is significant and increases the r... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Background
----------
The use of digital technology continues to rise, with an estimated 4.13 billion internet users worldwide \[[@ref1]\]. The United Kingdom has the second highest number of internet users in Europe \[[@ref2]\], and most people in the United Kingdom own a smartphone, with o... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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The Editors of *FEBS Open Bio* would like to thank all those who have given their time and expertise to review articles submitted for publication in Volume 8. Although *FEBS Open Bio* does not seek to judge the importance of submissions, our reviewers carefully scrutinize the experimental design and results of all pape... | {
"pile_set_name": "PubMed Central"
} |
{
"pile_set_name": "PubMed Central"
} | |
Introduction {#s1}
============
*Toxoplasma gondii* is an intracellular protozoan parasite which can be found in all warm-blooded animals. This parasite can only complete its full life cycle in cats, but nevertheless around 30% of the human population, globally, is estimated to be infected \[[@C1]--[@C3]\]. Current es... | {
"pile_set_name": "PubMed Central"
} |
One of the major limitations of nuclear magnetic resonance spectroscopy (NMR) and magnetic resonance imaging (MRI) is their intrinsic low sensitivity, which arises from low thermal equilibrium (Boltzmann) polarization of the nuclear spins at room temperature, even with the highest field instruments. This low sensitivit... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#sec1-2045894019879396}
============
Acute right heart failure (RHF) is a complex syndrome with structural and functional cardiac abnormalities of the right ventricle (RV).^[@bibr1-2045894019879396]^ RHF is a part of heart failure, whose mortality rate was 17% within 12 months of hospitalization.^[@bibr2... | {
"pile_set_name": "PubMed Central"
} |
Introduction and Background: Brain Stimulation and Hormesis (Walter J. Kozumbo) {#section1-1559325816685467}
===============================================================================
For a number of years, the US Air Force Office of Scientific Research (AFOSR) has supported research to elucidate and engage brain... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#s1}
============
Predicting the outcome for the level of activities of daily living (ADL) is important in the rehabilitation of stroke patients, and various methods are used. One easy-to-use method of prediction is calculation of the initial ADL level and final ADL level[@r1], [@r2]^)^. The Functional I... | {
"pile_set_name": "PubMed Central"
} |
Astaxanthin in the diet was used to degrade the oxidative stress caused by microcystin-LR, and bioaccumulation was significantly affected by the astaxanthin content. The appropriate content of astaxanthin in feed may be around 9--12 mg/g and it may make the crayfish *Procambarus clarkii* a more secure food for people.
... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Parkin, a RING-HECT hybrid E3 ubiquitin ligase ([@B1]), is mutated in most cases of autosomal recessive early onset Parkinson disease, which is a neurodegenerative disease associated with loss of dopaminergic neurons in the midbrain ([@B2], [@B3]). Parkin plays a central role in mitochondrial... | {
"pile_set_name": "PubMed Central"
} |
The authors confirm that all data underlying the findings are fully available without restriction. All relevant data are within the paper.
Introduction {#s1}
============
During robot assisted laparoscopic radical prostatectomy (RALRP), adequate surgical exposure requires the application of a CO~2~ pneumoperitoneum (... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Intestinal inflammation in fish is a detrimental condition that affects growth and the ability to respond to pathogens \[[@B1]\]. Preventing this pathology is of particular relevance for fish farming as small fish size and/or high fish mortality drastically affect the competitiv... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Hepatocellular carcinoma (HCC) is the fifth most common malignancy in the world and its incidence is increasing.[@B1] But, HCC is usually found in advanced stages and often associated with other comorbidities, making curative therapies only be applicable to less than 30-40% of the patients.[@... | {
"pile_set_name": "PubMed Central"
} |
Supported in part by grants from the Emory University Research Committee, the Emory-Egleston Children\'s Research Center, the American Lung Association, the American Lung Association of Georgia, and by Biomedical Research Support Grant SO7RRO5364 and United States Public Health Service Grant AI21072.
| {
"pile_set_name": "PubMed Central"
} |
Introduction {#ejoc201801745-sec-0010}
============
Indoles have been an important target in organic synthesis ever since Baeyer reported the first synthesis of the parent heterocycle in 1866.[1](#ejoc201801745-bib-0001){ref-type="ref"} In these early days of organic chemistry, many classical methods (e.g. the Fischer... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Biodiversity refers to the variability of life on Earth, ranging from genetic variation to ecosystem diversity (Gaston [@CR21]). Taxonomic species diversity, one of the most commonly studied facets of biodiversity, does not consider that species have different traits (Villéger et al. ... | {
"pile_set_name": "PubMed Central"
} |
Risk factors for in-stent restenosis, such as diabetes mellitus, diameter of the treated artery, length of the lesion and localisation are well known. In-stent restenosis (ISR) results from excessive fibroproliferative and inflammatory responses to the insult on the arterial wall, leading to neo-intimal proliferation.
... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-micromachines-10-00838}
===============
Manufacturing technologies for material removal have been constantly evolving to fulfill consumer requirements. Currently, downscaling of processes such as machining, injection molding, and electric discharge machining (EDM) is needed to produce microscale... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Food animals such as cattle, poultry and pigs have been extensively reared worldwide, not only as a source of food but also a source of income. The modes of productions are intensive \[[@CR1]\], due to the rapidly increasing demand for livestock products driven by human population gro... | {
"pile_set_name": "PubMed Central"
} |
All relevant data are within the paper.
Introduction {#sec001}
============
Recently, much attention has been focused on polymeric composite materials filled with nano-sized particles called nanocomposites \[[@pone.0150043.ref001]\]. Starch nanoparticles (SNPs) are considered one of the most promising polymers for fa... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Propylthiouracil (PTU)-induced severe hepatotoxicity is a relatively rare occurrence, despite observed transient increases in liver function test values at the initiation of treatment \[[@B1],[@B2]\]. A one in 10,000 incidence of liver failure following PTU treatment has been reported in the ... | {
"pile_set_name": "PubMed Central"
} |
Bcl2-associated athanogene 3 (BAG3) protein is a member of BAG family of co-chaperones that interacts with the ATPase domain of the heat shock protein (Hsp) 70 through a specific domain known as BAG domain.^[@bib1]^ In addition to this structural domain, BAG3 also contains a WW domain that is a protein interaction modu... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The genus *Acinetobacter* is comprised of a number of Gram-negative species that are ubiquitous in the environment. Notably, some of the species within this genus have emerged as opportunistic human pathogens. *A. baumannii* is the most notorious among *Acinetobacter* species for causin... | {
"pile_set_name": "PubMed Central"
} |
An 87-year-old woman was admitted to our hospital with acute heart failure, NYHA class IV. An echocardiography revealed severe mitral regurgitation and heart failure with pulmonary hypertension. She had been diagnosed as having severe mitral stenosis and had undergone mitral valve replacement with a 27-mm Carpentier-Ed... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION
============
Intraoperative neuromonitoring (IONM) has been widely performed to prevent permanent neurological injury in high-risk spine surgeries. There is no definitely established consensus regarding the feasibility of transcranial motor evoked potential (TcMEP) monitoring, however TcMEP monitoring has... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Gastrointestinal stromal tumors (GISTs) are the most common type of subepithelial tumor of the gastrointestinal tract (GI) and account for only 0.1% to 0.3% of all GI tumors.([@B1]) After finding out that GISTs originate from the interstitial cell of Cajal, an immunohistochemical marker CD 11... | {
"pile_set_name": "PubMed Central"
} |
Increased signal intensity on noncontrast T1-weighted magnetic resonance imaging (MRI) scans in various healthy brain structures (notably the dentate nucleus \[DN\] and globus pallidus) after repeated administration of linear gadolinium (Gd)-based contrast agents (GBCAs) was first reported in early 2014.^[@bib1]^ A num... | {
"pile_set_name": "PubMed Central"
} |
Related literature {#sec1}
==================
For applications of anthranilic acid derivatives, see: Congiu *et al.* (2005[@bb5]); Nittoli *et al.* (2005[@bb9]). For a related structure, see: Bahadur *et al.* (2007[@bb2]); For bond-length data, see: Allen *et al.* (1987[@bb1]). For ring puckering parameters, see: Crem... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Cerec CAD/CAM machines are currently used to manufacture ceramic restorations based on computer-assisted design and produce a restoration on a single dental appointment. These restorations, commonly made with ceramic material, are becoming increasingly popular worldwide ([@B1]-[@B4]). Because... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Currently, we are observing an increase of the incidence of colorectal cancer (CRC). In 2012, according to GLOBCAN, there were 1360000 new CRC cases, which with 9.7% made it the third most common cancer after lung and breast cancers \[[@B1], [@B2]\]. While causes of CRC remain u... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
The epidermal growth factor receptor (EGF-R) remains one of the best-established targets for anti-tumor therapies. This receptor is involved in cellular processes that contribute to the survival of epithelial cells. Deregulation of the EGF/EGF-R pathway by receptor overexpression or c... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Since December 2019, an increasing number of pneumonia cases caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, Hubei, China, and subsequently, an outbreak of coronavirus disease 2019 (COVID-19) swept the globe \[[@CR1]--[@CR4]\]. As of Februa... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#Sec1}
============
Renal dysfunction and worsening of renal function are frequently found in acute heart failure patients and are both associated with prolonged hospital stay, and higher risk of rehospitalization and mortality \[[@CR1]--[@CR7]\]. The Relaxin in Acute Heart Failure (RELAX-AHF) trial stud... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
The intricacies of embryonic development have captivated developmental biologists for centuries. The process by which a single cell undergoes gastrulation, morphogenesis and organogenesis to ultimately give rise to a fully formed body still captures the curiosity of scientists. This cur... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Type 2 diabetes mellitus (T2DM) is a chronic progressive disease affecting over 370 million patients worldwide in 2012 \[[@CR1]\]. In France, the prevalence of T2DM has been estimated to be around 5.5 % in 2012 and this figure is constantly rising as obesity and ageing of the population p... | {
"pile_set_name": "PubMed Central"
} |
mSystems® *vol. 3, no. 2, is a special issue sponsored by Janssen Human Microbiome Institute (JHMI)*.
PERSPECTIVE {#s0}
===========
Nature selects for individuals based upon the relative fitness of their phenotypes. Accordingly, evolutionary biology has focused on discovering the genomic determinants of fitness, with... | {
"pile_set_name": "PubMed Central"
} |
**Dear Editor,**
Nowadays, essential oils are used in different products such as food as natural antioxidants, antibacterial and flavoring compounds ([@A20128R1]). Essential oils are used as a replacement for chemical preservatives such as butylated hydroxytoluene (BHT) and tertiary butyl hydroquinone (TBHQ) that can ... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
In 1989 the concept of epilepsy syndromes was defined as "clusters of signs and symptoms customarily occurring together" \[[@CR1]\]. This definition based on electroclinical features had the aim of facilitating clinical practice and research. Over time the "epilepsy syndromes" concept has... | {
"pile_set_name": "PubMed Central"
} |
*Rogha M, Najafi N, Azari A, Kaji M, Pourmoghaddas Z, Rajabi F, Rezaee *M*. (Islamic Azad University, Iran)*. ***Non-Alcoholic Steatohepatitis in a sample Iranian Adult Population***. *Int J Prev Med 2011; 2: 24-27*.
Professor Roghan and his teams' objective in this study was to assess the prevalence of Non Alcoholic ... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Dendritic cells (DCs) are a heterogeneous group of bone marrow-derived cells within various organs, which display different cell surface phenotypes and serve different functions depending on location, development, and activation status. DCs bridge two arms of the immune response: the innate immun... | {
"pile_set_name": "PubMed Central"
} |
Background {#Sec1}
==========
Parasitic diseases caused by a wide range of arthropods, helminths and protozoans can cause serious, even life-threatening clinical conditions in dogs and cats, with a number of them also affecting the human population, due to their zoonotic potential, a situation that requires a One Heal... | {
"pile_set_name": "PubMed Central"
} |
Phosphorylation is an important protein post-translational modification. Phosphoproteomics experiments have successfully identified thousands of phosphorylation sites, predominantly using CID with relatively low resolution ion trap detection ([@r1]--[@r3]). For phosphoproteomics data to be of most use to the wider biol... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-sensors-20-02483}
===============
Intelligent Transportation System (ITS) aim at facilitating urban mobility economically and ecologically by connecting vehicles with the network infrastructure and therefore using various information services. In general, five types of services are expected to b... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
The family neurotrophic tyrosine receptor kinase (NTRK), also known as tropomyosin receptor kinases (Trk), includes receptors regulating synaptic strength and plasticity in the mammalian nervous system \[[@B1]\]. NTRK1 is one of the three major family members. NTRK1 is synthesiz... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction
===============
Respiratory syncytial virus is one of the most leading causes that lead to lower respiratory tract disease in infants and young children.^\[[@R1][@R2][@R3][@R4][@R5]\]^ It mostly occurs in infants of 2 to 3 months old with high morbidity and mortality.^\[[@R6][@R7][@R8]\]^ The major ris... | {
"pile_set_name": "PubMed Central"
} |
1.. INTRODUCTION
================
Idiopathic scoliosis is the most common form of scoliosis and its incidence in the total nubmer of scoliosis is from 67% to 90% depending on types of reasrch and the observed age groups. ([@R1], [@R2], [@R3]). It is present in 2 -- 4% of children aged from 10 to 16 years of age ([@R4]... | {
"pile_set_name": "PubMed Central"
} |
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"pile_set_name": "PubMed Central"
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All relevant data are within the paper and its Supporting Information files.
Introduction {#sec005}
============
Stroke is a leading cause of disability in western society \[[@pone.0139746.ref001]\]. The European Registers of Stroke study (EROS) show that of 2000 patients with first-ever strokes, 40% had a poor outco... | {
"pile_set_name": "PubMed Central"
} |
Subscapularis (SSc) tendon tears are increasingly recognized and are present in up to half of all arthroscopic rotator cuff operations.^[@bibr4-2325967120913036],[@bibr7-2325967120913036],[@bibr25-2325967120913036]^ As the largest rotator cuff muscle and anterior portion of the rotator cuff force couple, the SSc is vit... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s1}
============
Sulfide, a common toxin, may be harmful for organisms by reducing the affinity of hemoglobin to oxygen [@pone.0081885-Carrico1], inhibiting the activity of cytochrome c oxidase and succinate oxidase complexes [@pone.0081885-Beauchamp1], [@pone.0081885-Khan1], depolarizing mitochondria [... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Natural antisense transcripts (NATs) are endogenous transcripts that contain sequences complementary to each other. NATs have been shown to regulate gene expression by generating small RNAs from the overlapping region ( [@ref-15]). NATs are classified into two subgroups according to the site ... | {
"pile_set_name": "PubMed Central"
} |
ANNOUNCEMENT {#s1}
============
Group A *Streptococcus* (GAS) (Streptococcus pyogenes), which is responsible for many life-threatening invasive infections, is a highly diverse and rapidly emerging pathogen ([@B1], [@B2]). As more than 200 *emm* types of GAS have been identified worldwide, attempts to develop a vaccine... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction
================
Composite materials are obtained by assembling at least two non-miscible (but presenting a high adhesion capability) constituents that confer to the assembly physical properties not present in the constitutive materials taken alone \[[@b1-sensors-14-07394]\]. Composite materials are m... | {
"pile_set_name": "PubMed Central"
} |
GENOME ANNOUNCEMENT
===================
The cricket industry has been devastated worldwide recently by the *Acheta domesticus* densovirus (AdDNV) ([@B1]--[@B4]). We also observed several, thus far unknown, viruses such as volvoviruses, which have circular, single-stranded DNA (ssDNA) genomes ([@B5]), and a new densovi... | {
"pile_set_name": "PubMed Central"
} |
INTRODUCTION {#sec1-1}
============
Persistent Müllerian duct syndrome (PMDS) is a rare disorder in which a normally virilized 46 XY male retains Müllerian duct structures. Beginning at 7 weeks of gestation, Sertoli cells release anti-Müllerian hormone (AMH) which leads to the regression of the Müllerian ducts.\[[@ref... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijms-21-01770}
===============
Diabetes mellitus (DM), a chronic disease characterized by impaired glucose homeostasis, is a rising epidemic worldwide. The World Health Organization (WHO) reported that, globally, more than 425 million people are living with diabetes, and in the United States alo... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1}
===============
Microglia have been known to be present in the characteristic plaques of Alzheimer disease since the first descriptions of these cells by del Rio Hortega and Penfield in the 1920s \[[@B1]\], but half a century would pass before attention returned to these cells. The first sugges... | {
"pile_set_name": "PubMed Central"
} |
1.. Introduction
================
Ubiquitous positioning is considered to be the main goal for today\'s Location-Based Services (LBS). While satellite-based navigation has achieved great advances in the past few decades and has been applied to both military and civilian applications in a mature manner, positioning and... | {
"pile_set_name": "PubMed Central"
} |
Gozukara Bag HG. Association between *COMT* gene rs165599 SNP and schizophrenia: A meta‐analysis of case‐control studies. Mol Genet Genomic Med. 2018;6:845--854. 10.1002/mgg3.468
1. INTRODUCTION {#mgg3468-sec-0005}
===============
Schizophrenia (MIM \# 181500) is a complex psychiatric disorder in which genetic and en... | {
"pile_set_name": "PubMed Central"
} |
Background
==========
Myopia is a serious health problem in many countries, and the incidence of high myopia appears to be rising in Asia and other parts of the world. In East Asian countries, the prevalence of myopia is high, and the number of new cases and the severity of the condition continue to increase \[[@B1]\]... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Ultrasound is used to evaluate venous diseases of the lower extremities [@R0147-0001] [@R0147-0002] [@R0147-0003] . Pathological retrograde blood flow, i. e. reflux, in the superficial veins of the lower extremities indicates chronic venous disease. B-mode ultrasound is used for anatomical ma... | {
"pile_set_name": "PubMed Central"
} |
Introduction
============
Breast cancer, with increasing rates of incidence and mortality worldwide, is a major cause of mortality within female malignancies ([@b1-ol-0-0-7438],[@b2-ol-0-0-7438]). Due to its late disease presentation, breast cancer exhibits poor prognosis and frequently presents with distant metastase... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec1-ijms-20-05099}
===============
Forage legumes are important in agricultural systems as feed sources for livestock. Among them, alfalfa (*Medicago sativa* L.) is the most cultivated forage legume in the world \[[@B1-ijms-20-05099]\] and one of the most widely distributed forage crops from Patagon... | {
"pile_set_name": "PubMed Central"
} |
1. Introduction {#sec0005}
===============
Positive strand virus genomes serve as both a messenger RNA and templates for genomic RNA synthesis, encapsidation and subgenomic mRNA transcription ([@bib0140], [@bib0160]). The coordination among different stages of virus infection has been the focus for RNA virology. It is... | {
"pile_set_name": "PubMed Central"
} |
Introduction {#s0005}
============
In nature, symmetry can be found everywhere, including macroscopic and microcosmic objects. The palindrome, as one of the symmetrical sequences, consists of two arms of similar DNA-with one inverted and complemented relative to the other around a central point, usually nonhomologous ... | {
"pile_set_name": "PubMed Central"
} |
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