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The dataset generation failed
Error code: DatasetGenerationError
Exception: CastError
Message: Couldn't cast
PMID: string
Title: string
Abstract: string
PublicationDate: string
-- schema metadata --
pandas: '{"index_columns": [], "column_indexes": [], "columns": [{"name":' + 539
to
{'PMID': Value('string'), 'Abstract': Value('string'), 'PublicationDate': Value('string')}
because column names don't match
Traceback: Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1405, in compute_config_parquet_and_info_response
fill_builder_info(builder, hf_endpoint=hf_endpoint, hf_token=hf_token, validate=validate)
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 597, in fill_builder_info
num_examples_and_sizes: list[tuple[int, int]] = thread_map(
File "/src/services/worker/.venv/lib/python3.9/site-packages/tqdm/contrib/concurrent.py", line 69, in thread_map
return _executor_map(ThreadPoolExecutor, fn, *iterables, **tqdm_kwargs)
File "/src/services/worker/.venv/lib/python3.9/site-packages/tqdm/contrib/concurrent.py", line 51, in _executor_map
return list(tqdm_class(ex.map(fn, *iterables, chunksize=chunksize), **kwargs))
File "/src/services/worker/.venv/lib/python3.9/site-packages/tqdm/std.py", line 1169, in __iter__
for obj in iterable:
File "/usr/local/lib/python3.9/concurrent/futures/_base.py", line 609, in result_iterator
yield fs.pop().result()
File "/usr/local/lib/python3.9/concurrent/futures/_base.py", line 446, in result
return self.__get_result()
File "/usr/local/lib/python3.9/concurrent/futures/_base.py", line 391, in __get_result
raise self._exception
File "/usr/local/lib/python3.9/concurrent/futures/thread.py", line 58, in run
result = self.fn(*self.args, **self.kwargs)
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 469, in retry_validate_get_num_examples_and_size
validate(pf)
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 535, in validate
raise TooBigRowGroupsError(
worker.job_runners.config.parquet_and_info.TooBigRowGroupsError: Parquet file has too big row groups. First row group has 1102253535 which exceeds the limit of 300000000
During handling of the above exception, another exception occurred:
Traceback (most recent call last):
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1815, in _prepare_split_single
for _, table in generator:
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 692, in wrapped
for item in generator(*args, **kwargs):
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/packaged_modules/parquet/parquet.py", line 106, in _generate_tables
yield f"{file_idx}_{batch_idx}", self._cast_table(pa_table)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/packaged_modules/parquet/parquet.py", line 73, in _cast_table
pa_table = table_cast(pa_table, self.info.features.arrow_schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2272, in table_cast
return cast_table_to_schema(table, schema)
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/table.py", line 2218, in cast_table_to_schema
raise CastError(
datasets.table.CastError: Couldn't cast
PMID: string
Title: string
Abstract: string
PublicationDate: string
-- schema metadata --
pandas: '{"index_columns": [], "column_indexes": [], "columns": [{"name":' + 539
to
{'PMID': Value('string'), 'Abstract': Value('string'), 'PublicationDate': Value('string')}
because column names don't match
The above exception was the direct cause of the following exception:
Traceback (most recent call last):
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 1428, in compute_config_parquet_and_info_response
parquet_operations, partial, estimated_dataset_info = stream_convert_to_parquet(
File "/src/services/worker/src/worker/job_runners/config/parquet_and_info.py", line 994, in stream_convert_to_parquet
builder._prepare_split(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1702, in _prepare_split
for job_id, done, content in self._prepare_split_single(
File "/src/services/worker/.venv/lib/python3.9/site-packages/datasets/builder.py", line 1858, in _prepare_split_single
raise DatasetGenerationError("An error occurred while generating the dataset") from e
datasets.exceptions.DatasetGenerationError: An error occurred while generating the datasetNeed help to make the dataset viewer work? Make sure to review how to configure the dataset viewer, and open a discussion for direct support.
PMID string | Abstract string | PublicationDate string |
|---|---|---|
1129941 | Studied was the vitamin B12 activity of minced meat obtained under productional conditions from freshly cooled. | 1975-01-01 |
8585095 | We studied the ability of four commercially available antivenoms to neutralize several toxic and enzymatic activities of Bothrops asper (terciopelo) venom from Costa Rica. Experiments with preincubation of venom and antivenom were carried out to test the neutralization of lethal, hemorrhagic, coagulant and indirect hem... | 1995-09-01 |
9592208 | This paper presents a detailed review of Suicide, the sociological classic by Durkheim, 100 years after it was first published, The first part of the article focuses on the author's interest in the theme, within the scope of concerns on the importance of studying suicide dating from the 18th century. The article then p... | 1998-05-21 |
9592209 | This article discuss the complex relations between drugs and violence. Drawing on empirical studies and current forms of discourse, it analyzes conceptual and methodological problems related to the establishment of causal nexuses, risks, and associations. By demonstrating the theoretical and practical difficulties in s... | 1998-05-21 |
9592210 | This study is based on a medical audit of the Vila Municipal Health Clinic, Pelotas, Rio Grande do Sul. We collected data from family medical records in 1992,1993, and 1994. The data concerned the Women's Integral Health Care Program. We collected information on age, visits for medical and non-medical reasons, blood pr... | 1998-05-21 |
9592211 | On the basis of social representations, we detected gender differences in family and individual living experiences for people with Hansen's disease (HD, or leprosy) in a sample of 202 HD patients (132 men and 70 women) enrolled in a public treatment and control program in Ribeirão Preto, São Paulo State. Information ... | 1998-05-21 |
9592212 | This study focuses on the Pediatric Clinic of the UNICAMP University Hospital, teaching and care facility belonging to the Brazilian National Health System, providing secondary and tertiary health care for children aged 0 to 18 years. A total of 221 questionnaires were applied with users of the general pediatric out pa... | 1998-05-21 |
9592213 | This study presents a diagnosis and evaluation of the availability of services related to family violence against women in Greater Metropolitan Buenos Aires, Argentina. The paper focuses on institutional development, theoretical foci, intervention modalities, and production of information and research. Existing network... | 1998-05-21 |
9592214 | Drug advertisements for prescription drugs gathered from private clinics and hospitals in southern Brazil were analyzed. None of the 127 advertisement inserts that were analyzed complied with all the criteria specified by Brazilian legislation. The official Brazilian generic drug name was present in 95% of the advertis... | 1998-05-21 |
9592215 | This study presents the results of research done at the Pedro II Psychiatric Center in 1995, as part of a partnership between the Center and the Universidade do Estado do Rio de Janeiro. Research includes the development of a profile for inpatients based on clinical and socioeconomic data from patient files, emergency ... | 1998-05-21 |
9592216 | Failure of intensive chemotherapy to control schistosomiasis in a highly endemic area of Northeast Brazil led to the hypothesis that sociodemographic and/or behavioral variables could be involved in the persistent transmission. A univariate analysis of such variables in relation to infection by Schistosoma mansoni show... | 1998-05-21 |
9592218 | This article is part of a larger study in which epidemiological and anthropological methods were used to help understand the production and maintenance of schistosomiasis in a small endemic area in Pernambuco State. A cross-sectional study identified several local risk factors for schistosomiasis, quantifying socioecon... | 1998-05-21 |
9592217 | The main objective of this study was to evaluate the effectiveness of the Program Targeting Children with 'Chest Wheezing' carried in the city of Embu, São Paulo. The study analyzed a total of 434 children aged zero to 14 years, admitted to the program from May 1988 to July 1993. Over 90% had never been treated for th... | 1998-05-21 |
9592219 | The aim of this study was to evaluate the effectiveness of an educational program carried out in 1993. The intervention took place after the first external quality assessment in coproparasitology, conducted in 77 laboratories of Havana City. Centers receiving training were compared with those that did not, and better r... | 1998-05-21 |
9592221 | This study aimed to establish a correlation between anthropometric and socioeconomic variables and repetition in school for first grade pupils, as well to determine the predictive value of such variables vis-à-vis repetition. A study with a prospective and concurrent approach was developed in four elementary schools i... | 1998-05-21 |
9592220 | This paper focuses on specific aspects of male sexuality and how this sexual identity is built in the Aids era, based on conversations with low-income youth, ages 14-21 years, living in Greater Metropolitan Rio de Janeiro. We examine how Aids is perceived and investigate sexuality in this epidemic context. The goal is ... | 1998-05-21 |
9592222 | This study reports on deaths due to acute rheumatic fever declined: total from 7.68 to 1.08. ARF-AMR declined (-93.5%) as did CRHD-AMR (-85.1%). Proportional death by ARF and CRHD in patients 45 years old and younger increased. Venezuela experienced a continuous decline in RF-AMR from 1955 to the l980s, followed by a p... | 1998-05-21 |
9592223 | This study evaluates food intake of 244 children between ages 7-13 years using records of ingested foods on three non-consecutive days. The study analyzes energy and nutrient adequacy based on standards for the Brazilian population. Diet was generally found to be energy-deficient: meals consumed at the CIEPs met less t... | 1998-05-21 |
9592224 | This paper provides a checklist of 15 known species of the Triatominae subfamily in Maranhão State. On the coastal São Luís Island there are a total of 10 species associated with sylvatic areas (Eratyrus mucronatus, Psammolestes tertius, Panstrongylus diasi) and periurban and urban areas (Panstrongylus geniculatus, ... | 1998-05-21 |
9592226 | As more is known about the complexity of the relationships between social, economic, and environmental contexts and the health of the population, it appears clear that the concepts of illness and health, while not independent, are not synonymous. A major challenge now facing the field of public health is to organize a ... | 1998-05-21 |
9592225 | Drug advertisements for non-prescription emphasize absence of risks, with claims such as "no contraindications" inducing consumers to use such drugs indiscriminately. The study showed that drugs were advertised like any other merchandise with no concern over fundamental information such as product identification, preca... | 1998-05-21 |
9592227 | The nationwide use of a 'Multimixture' a formula based on alternative foods such as rice and/or wheat bran, sesame and squash seeds, cassava, beet and carrot leaves, several indigenous leafy vegetables, and ground egg shells has been proposed by the National Institute of Food and Nutrition (INAN) as an official solutio... | 1998-05-21 |
9593996 | The presence of tuberculosis in the upper Rio Negro region showed 699 cases, with an extremely high annual incidence rate of over two per thousand, predominantly pulmonary cases, and distribution of the disease among all age groups. Data on compliance with outpatient treatment are not reliable. In the present context o... | 1998-05-21 |
9593998 | Modern reproductive technologies, particularly in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT), have made possible the establishment of new families through the birth of hundreds of thousands of children worldwide. Meanwhile, these technologies have compelled men to face the possibility of interv... | 1998-05-21 |
9593999 | The Program for Integrated Women's Health Care a program regulating fertility. This raised suspicions as to disguised promotion of birth control. However, a brief analysis of the history of this program and its social significance suggests that the PAISM was a pioneering undertaking (even within the international scena... | 1998-05-21 |
9594000 | The purpose of the study is to explore some characteristics of women's perspectives on their sexuality, as there is information that associates the population's sexual culture with the incidence of cervical cancer. The value of sexual pleasure, sexual activity after menopause, and ways of preventing cervical cancer are... | 1998-05-21 |
9594001 | Reproductive-age women, especially in developing countries, have failed to receive proper attention from the health care sector except during pregnancy. This study's objective was to contribute to the knowledge of the most frequent causes of death in this population group. The main purpose was to evaluate the occurrenc... | 1998-05-21 |
9594002 | Brazil has a high prevalence of tubal ligation. The hypothesis that it indicates undercover birth control efforts specifically addressed to the poorest sector of Brazilian society has been raised. The purpose of this paper is to evaluate whether there are differences in rates of tubal ligation depending on socioeconomi... | 1998-05-21 |
9594003 | Female sterilization is the most widely used contraceptive method among Brazilian women, although it has not been provided by the National Health System. Due to its legal ambiguity, it has not been recommended by Medical Boards as an ethical procedure. A study in which 3,149 women were asked about contraceptive use was... | 1998-05-21 |
9594004 | The objective of this paper is to point out the positive and negative aspects of female sterilization as seen by two groups of sterilized women in Florianópolis, Santa Catarina, Brazil, based on a sociological discussion of their present health status, evaluating the associations that they generally make with the fact... | 1998-05-21 |
9594005 | The article deals with the psychosocial and cultural dimensions of sexually transmitted diseases. Based on results from a qualitative study with lower-class males and females (young and adult) from a neighbourhood in the metropolitan area of Buenos Aires, the author discusses how lay beliefs (about symptoms, transmissi... | 1998-05-21 |
9594006 | This study aims to identify analytical approaches to situate men in processes pertaining to reproductive health. We challenge the position that identifies them only as actors that can support improvements in the health of women and children. More recently there has been a concern over reshaping their role, as individua... | 1998-05-21 |
9594007 | Vasectomy service providers at the Clínica del Hombre (Men's Clinic) in Bogotá, Colombia, construct their representations concerning male sterilization on the basis of biomedical discourse, their interaction with clinic users, and their own life experiences. During provision of such services, the counselors are the h... | 1998-05-21 |
9594008 | The population's high growth rate, age profile, and geographical distribution have aroused increasing public concern in Paraguay. The country is involved in a moderate demographic transition, compatible with the consequences of modernity and the uneven rate of both social and economic changes. Reduction of mortality an... | 1998-05-21 |
9594009 | This article is an analytical essay on a historical moment in the formation of public health thinking vis-à-vis adolescent pregnancy: the 1960s. Its relevance lies in the fact that several assertions produced then still bear great influence on ideas and models concerning adolescent maternity in current public health t... | 1998-05-21 |
9594010 | Historically, family planning programs have targeted women almost exclusively. More recently it has become clear that men have a strong influence on their partners' use of contraception, either by opposing the use of any or one specific method, or by deciding that a woman has to either use a given method or be steriliz... | 1998-05-21 |
9594011 | Climacteric is constructed by medicine, lay knowledge, and the social sciences. This article examines the interrational models involving these different discourses and proposes that the contribution of the social sciences lies in a reformulation of the cognitive base of the health professions at an integrative level. | 1998-05-21 |
9594012 | Catholics do not follow official Roman Catholic teachings on matters of sexuality and reproduction, including the position that contraception, even for married couples, is always evil, and that direct abortion, even to save a woman's life, is always illegal. Less well known is the extent of the Church's involvement in ... | 1998-05-21 |
9664733 | Project Audit of diagnostic and therapeutic procedures in patients with acute coronary syndromes was approved by the Ministry of Health of the Slovak Republic on 13 May 1996. The essence of the project resides in a systematic and complex analysis of quality of provided medical care and the use of sources with the seeki... | 1998-07-17 |
9664735 | The therapy of AMI is aimed at the prevention of death, minimalization of discomfort caused by the disease and the reduction of the infarction focus (as soon and as markedly as possible) since the success of this step links with the later short-term as well as the long-term prognoses of the patient. (Tab. 2, Ref. 15.) | 1998-07-17 |
9664734 | Diabetes mellitus type 2 (DM type 2) is a common disease that is associated with high mortality and morbidity due to macrovascular and microvascular complications. CHD mortality and morbidity is 2--3 times higher in diabetic than in non-diabetic patients/. There are many potentially atherogenic factors in diabetes thes... | 1998-07-17 |
9664736 | The article reviews the possibilities of biochemical markers in coincidence with the assessment of prognosis in acute coronary syndromes and in the revealing of effectivity of their therapy. The current options of clinical biochemistry in many cases allow to supplement, confirm, or exclude the results of modern physica... | 1998-07-17 |
9664737 | The data gained from clinical studies in the past years have indicated that the thrombolytic therapy (TL) has favourable effect on patients with acute myocardial infarction (AMI). It is aimed at reperfusion in the ischaemic area, a decrease in the extent of infarction site and a decrease in mortality. TL administered w... | 1998-07-17 |
9664738 | Reperfusion arrhythmias originate as a consequence of the complex of cellular and humoral reactions accompanying the opening of coronary artery. As the primary cause of their generation are considered the chemically defined substances that are produced and accumulated in myocardium during reperfusion. The key role id a... | 1998-07-17 |
9664739 | In addition to ventricular arrhythmias, various forms of supraventricular arrhythmias (SVA) and atrioventricular (AV) and intraventricular (IV) conduction disturbances occur also in acute myocardial infarction (AMI). In the setting of AMI, SVA may be caused by relevant atrial ischemia or infarction. SVA complicate the ... | 1998-07-17 |
9664740 | On the basis of long-term personal experiences and critical evaluation of the present literatury sources authors described the role of invasive diagnostic methodes and transcathetral and cardiosurgical possibilities in the recognition and therapy of acute coronary syndromes. These techniques are, and in the forthcoming... | 1998-07-17 |
9664741 | The confirmation of ischaemic disease of the heart increases the probability of death due to cardiovascular causes to more than 80%. The overcoming of myocardial infarction increases, according to the past AHA data, the risk of the origin of a new coronary episode 5 or 7 fold. The necessity of decreasing this risk in t... | 1998-07-17 |
9664742 | Endothelium represents a large paracrine gland with an enormous reactive surface. By means of its numerous vasodilation and vasospastic factors it manages the basal and working tonus of vessels and thus also the regional flow and the access of target tissues to hormones and metabolic substrates. It manages also the pro... | 1998-07-17 |
10036384 | 3)- beta - D -Glucan and she showed some signs of improvement. Case 2: A 52-year-old male with jaundice was hospitalized in November 1997. The third day following the operation on the pancreas head carcinoma, the body temperature rose higher with a negative blood culture. The fourth day, the plasma beta -glucan concent... | 1999-02-26 |
10036385 | Clinical isolates which belong to the "Streptococcus milleri" group were identied by the referral uorogenic phenotypic tests described by Whiley et al. and a rapid, commercially available test kits; Fluo-Card Milleri (KEY Scientific Products, Round Rock, Tex., U.S.A.) to the species level. Of 218 clinical isolates incl... | 1999-02-26 |
10068814 | Intensive care of the surgical patient is an integral part of the treatment and continuing medical education mission of surgery. Working on the intensive care unit educates surgeons with regard to emergency treatment, pathophysiological thinking, and judging the risks of surgical procedures. The importance of preoperat... | 1999-03-09 |
10068815 | Intensive care medicine for both surgical and medical patients has a common scientific and clinical basis. In critically ill patients the medical conditions are complex and can be managed only by specialists thoroughly trained in intensive care medicine. Therefore, surgeons as well as anesthesiologists must have a deta... | 1999-03-09 |
10068816 | The complexity of daily clinical work requires a sophisticated collaboration of surgery and anesthesiology. This can be accomplished by a rational approach to the following topics: clear definition of areas of competence respecting the principle of mutual trust, integration of anesthesiologists into the basic physical ... | 1999-03-09 |
10068817 | Soaring health care costs are also forcing surgeons and anaesthesiologists to introduce practice patterns that allow more efficient use of expensive hospital resources. Because perioperative ward expenditures account for approximately one-third of the hospital costs incurred for surgical inpatients, with personnel cost... | 1999-03-09 |
10068818 | The increasing number of high-risk patients and the limited number of intensive care beds and shrinking hospital budgets make it necessary to review perioperative management processes. Analyzing the data of the Heidelberg Anesthesia documentation system revealed improvement strategies in operating room management. The ... | 1999-03-09 |
10068819 | Perioperative management requires close cooperation between the referring practitioner, anesthesiologist, surgeon, and nursing staff. Standards in diagnostics, risk assessment, and choice of procedure, as well as integration of the anesthesiologist into the surgical out-patient department, are all important prerequisit... | 1999-03-09 |
10068820 | Solid tumors do not grow beyond a size of a few millimetres without supply of nutrients and growth factors by the vascular system. Only when tumors produce angiogenic growth factors new vessels are formed by sprouting of capillaries from the existing vascular system. The tumor can grow and tumor cells reach the circula... | 1999-03-09 |
10068821 | Video-assisted thoracoscopic surgery is now recommended for the treatment of primary spontaneous pneumothorax. We studied the validity of this method at our general surgical department in a prospective group with regard to effectiveness and complication rate. The combination of thoracoscopic bulla resection with tetrac... | 1999-03-09 |
10068822 | Intraoperative radiotherapy received IORT (32 applications). Chemotherapy and percutaneous radiotherapy had already been given to all patients with advanced and recurrent colorectal tumors. The intraoperative irradiation was performed through HDR iridium afterloading. A flexible flab--individually adapted to the "tumor... | 1999-03-09 |
10068823 | BACKGROUND: Although the majority of surgeons regard Hartmann's operation as therapeutic standard in perforations of the colon complicated by peritonitis this procedure has been critically discussed in recent years. Advocates of one-stage techniques criticized bad postoperative results was 19. Seventeen patients died p... | 1999-03-09 |
10068831 | Twenty-seven patients presenting with complete rectal prolapse were treated by extracorporal resection using a stapling device. The mean age of the female patients was 74 +/- 15 years, the mean operation time 61 +/- 17 min, the mean length of hospital stay 17 +/- 8 days. 96% of the patients suffered from at least one c... | 1999-03-09 |
10068832 | The aim of this study was to investigate postoperative und long-term results after radical tumor surgery in complicated colorectal cancers. One hundred and twenty-six: or perforation (42; 3.9%). Postoperative mortality was significantly higher in complicated than in uncomplicated cancers (19% after bowel obstruction, 3... | 1999-03-09 |
10068833 | Mechanical ventilation is a well-established strategy in intensive care medicine. ICU trauma patients require analgesia, and sedation mostly consists of benzodiazepines and opioids with increasing doses over time. The weaning period is complicated by the withdrawal syndrome, showing tachycardia, hypertonia, tachypnea a... | 1999-03-09 |
10068834 | Since 1996 thoracic surgery has been invoiced according to fixed reimbursement rates (Sonderentgelte, SE). The legislator argues that fixed reimbursement rates cover operation costs and justify a 20% reduction in reimbursement for nursing. In order to examine this assumption we performed a cost analysis of thoracic sur... | 1999-03-09 |
10068835 | Cryophlebectomy, a more recent technique in varicose veins surgery, was evaluated in comparision with conventional techniques. Group IA: Microphlebectomy, invaginative stripping of the long saphenous vein, tourniquet, n = 90; group IB: only microphlebektomie and tourniquet, n = 72. Group IIA: Cryostripping of the long ... | 1999-03-09 |
10068837 | Mesenteric cysts are a rare cause of disease. In our hospital we treated one patient who suffered from bilateral ureteral obstruction followed by hydronephrosis, caused by a large mesenteric cyst. Because of its extent complete enucleation--the surgical procedure of choice--was not possible. We opened the cyst and made... | 1999-03-09 |
10068836 | Intimal sarcoma of the pulmonary artery is an extremely rare type of malignant tumor of the large vessels. Despite systematic diagnostics, distinguishing between pulmonary emboli and tumors is difficult. We report a patient who was referred because of suspected embolic occlusion of the pulmonary artery. The operation w... | 1999-03-09 |
10068838 | Adrenocortical insufficiency (Addison's disease) is a functional diagnosis. At the beginning of this century, tuberculosis was recognized as the main etiological cause (50-70%). Today, however, tuberculosis represents only 10% of the cases. Adrenocortical insufficiency is mainly caused by autoimmune adrenalitis (more t... | 1999-03-09 |
10068839 | To optimise the microsurgical training in our clinic we organized a permanent possibility to practice microsurgical techniques of vascular anastomosis. This includes step-wise education by means of plastic materials, human placenta and the rat model. The most important role in this concept is played by the placenta. It... | 1999-03-09 |
10200355 | OBJECTIVE: To understand the allele structure and reveal genetic polymorphism of Y chromosome specific short tandem repeat (Y-specific STR) loci in Chinese Han population. METHODS: The authors used a set of five Y-specific STR loci which were tetrameric tandem repeat loci chosen from the Genome Database. EDTA-blood spe... | 1999-04-14 |
10200357 | OBJECTIVE: To understand polymorphism of HLA-DRB1, DQB1 in the Hans of north China and obtain more comprehensive and accurate data on genetics at DNA level. METHODS: Polymerase chain reaction-sequence specific primers (PCR-SSP) were used to determine HLA-DRB1, DQB1 alleles in 107 unrelated healthy Han individuals of no... | 1999-04-14 |
10200356 | OBJECTIVE: To compare the HLA-A locus in a population selected from Beijing (northern group) with that in a population selected from Guangzhou (southern group). METHODS: HLA typing was performed by using PCR/SSOP method. A pair of primer and 54 probes were used. RESULTS: In 18 alleles identified, the differences in gen... | 1999-04-14 |
10200358 | OBJECTIVE: To get preliminary genotype and allele frequency distributions of D6S366, D6S477, D12S375, D12S391 and PLA2A loci in Chinese Han population in Chengdu area and to validate more short Tandem repeat (STR) systems for forensic application. METHODS: The polymerase chain reaction (PCR) was used. Five STR systems ... | 1999-04-14 |
10200359 | OBJECTIVE: To observe the CA repeat polymorphism of the type I angiotensin II receptor gene on Chinese Han people, and evaluate the genetic linking to hypertension. METHODS: The CA repeat polymorphism at 3'-flanking region of AT1R gene was studied by amplified fragment length polymorphism (Amp-FLP ) in Chinese Han peop... | 1999-04-14 |
10200360 | OBJECTIVE: To study the genetic susceptibility of HLA-DQA1 alleles to duodenal ulcer in Chinese Hans from Wuhan and its nearby regions. METHODS: Seventy patients with duodenal ulcer and fifty healthy controls were examined for HLA-DQA1 genotypes. HLA-DQA1 typing was carried out by digesting the locus specific polymeras... | 1999-04-14 |
10200361 | OBJECTIVE: To analyze the frequency of mutation in exon 8 of Wilson's disease and 11 heterozygous (12.2%). The positive rate of mutation was 16.67%. The Arg778Leu mutation was validated by this study. CONCLUSION: The mutation in exon 8 of WD gene may play an important role in pathogenesis of Wilson's disease in Chinese... | 1999-04-14 |
10200362 | OBJECTIVE: To investigate the characteristics of mutations of exons 14 and 18 of Wilson's disease (WD) gene in Chinese patients. METHODS: The subjects of study included 60 unrelated normal controls and 44 unrelated WD patients. Genomic DNA was prepared from peripheral blood leukocytes by a salt-out method. Mutations of... | 1999-04-14 |
10200364 | OBJECTIVE: Investigating the correlation between the genotype and spinal muscular atrophy(SMA) clinical phenotype. METHODS: Neuronal apoptosis inhibitory protein(NAIP) gene analysis was performed by PCR amplification of exon 5 in 13 unrelated SMA patients with deletions of SMN gene. RESULTS: Two Type-I patients(2/5, 40... | 1999-04-14 |
10200363 | OBJECTIVE: To detect the relation between alpha1-antichymotrpsin(AACT)gene polymorphism and epsilon4 allele of apolipoprotein E (ApoE) gene in Alzheimer disease (AD) in Chinese. METHODS: The gene polymorphisms of ApoE and AACT were genotyped in 125 AD cases and 140 controls with PCR methods and RFLP typing. Then the as... | 1999-04-14 |
10200365 | OBJECTIVE: To search for the minimal overlap region of tumor suppressor gene in laryngeal carcinoma and discuss the correlation of p16 gene with laryngeal carcinogenesis. METHODS: Five microsatellite polymorphism markers near p16 gene were selected to detect loss of heterozygosity (LOH) and microsatellite instability (... | 1999-04-14 |
10200366 | OBJECTIVE: To determine the influence of aging and sex on the segregation of chromosome 21. METHODS: Lymphocytes were obtained from healthy donors of different ages, both sexes, and were treated with cytochalasin B. Binucleated cells were hybridized with chromosome 21 specific probe, and simultaneously, chromosome 21 l... | 1999-04-14 |
10200367 | OBJECTIVE: To study human ABO genotyping by means of multiplex PCR and restriction fragment length polymorphism. METHODS: Two specific fragments of ABO gene were simultaneously amplified in a single tube, and then the double restriction digestion with RE Kpn I and Alu I was performed in the same tube. The amplified pro... | 1999-04-14 |
10200368 | OBJECTIVE: To establish a rapid and convenient single strand conformation polymorphism (SSCP) analysis method for detecting the point mutation of non-deletional alpha-thalassemia. METHODS: The 543bp DNA fragment spanning the hot spot region mainly responsible for non-deletional alpha-thalassemia was nested amplified us... | 1999-04-14 |
10200369 | OBJECTIVE: To develope the method of two-color fluorescence in situ hybridization (FISH) assay and use it for detecting the aneuploidy frequency of human sperm chromosome. METHODS: Sperm sample was washed three times and the slides were prepared. The sperm heads were decondensed with dithiothreitol (DTT) and lithium di... | 1999-04-14 |
10399253 | OBJECTIVE: We examined the placental transfer of the calcium antagonists Flunarizine and Verapamil and their effects on the placental metabolism using the dual in vitro perfusion of the human placental lobulus. MATERIAL AND METHODS: Eight placental lobuli were perfused with either 10 micrograms/ml Flunarizine or Verapa... | 1999-07-10 |
10399254 | OBJECTIVE: The objective of the study was to analyse the prognostic impact of several criteria for median survival and recurrence free interval in patients with uterine sarcomas. Factors included to our analysis were the staging according to FIGO, DNA content (ploidy), mitotic index, histology, the kind of primary ther... | 1999-07-10 |
10399255 | OBJECTIVE: The purpose of this study was to evaluate the effects of opioid addiction on pregnancy, perinatal period, and the long-term development of mother and child. MATERIAL AND METHODS: Records of 44 opioid-dependent women and their children were analyzed. Thirty-three patients were enrolled in methadone maintenanc... | 1999-07-10 |
10399256 | This paper was intended to settle the question whether the so-called gentle sectio caesarea with a high skin incision as described by Cohen in 1972 could be applied in combination with a sectio on the level of the classic Pfannenstiel's incision which would be more satisfying cosmetically. Furthermore a comparison was ... | 1999-07-10 |
10399257 | OBJECTIVE: The objective of this retrospective analysis was to compare the obstetrical procedures at premature birth and delivery at term. The aim was to show the influence of gestational time on mode of delivery and neonatal state. MATERIAL AND METHODS: 339 births from breech presentation between 1988-1990 were compar... | 1999-07-10 |
10399258 | Few cases of surgical scar endometriosis have been reported yet, which may occur following episiotomies and caesarean sections. The classic presentation is that of a tender mass becoming symptomatic with menstruation. Patients are complaining of cyclic pain and pre-menstrual swelling. In our case, a 34-year-old gravida... | 1999-07-10 |
10399261 | OBJECTIVE: Endometriosis is one of the most common benign gynaecological diseases. Its aetiology is uncertain and there are many unanswered questions about its pathogenesis and treatment. MATERIAL AND METHODS: Medline search of relevant publications. RESULTS: Particularly the early stages of endometriosis, usually loca... | 1999-07-10 |
10399262 | Since February 1997 the Departments of Dentistry and Oral & Maxillofacial Surgery of the University of Munster, Germany, can be visited on the Internet on more than 1400 HTML pages. These Web pages have been organized using an especially designed database which ensures standardized layout of the presented information a... | 1999-07-10 |
10425500 | The long-postulated reactive intermediates of polar fluoride-inititated trifluoromethylations with Me(3)SiCF(3) (see scheme) were identified by NMR spectroscopy as(-) and(-)(.) | 1999-07-30 |
10467687 | In a study 112 patients with histologically confirmed mostly recurrent endometriosis underwent a "three-step" therapy. Surgical removal of endometriosis implants was followed by a 6-months treatment with 3.75 mg of leuprorelin acetate depot as monthly subcutaneous injection and a second look laparoscopy with removal of... | 1999-09-01 |
10467686 | The assessment of the activity of endometriosis provides a challenge during endoscopic procedures. Novel approaches can be developed in future based on more detailed understanding of the mechanisms of the pathogenesis of endometriosis. Angiogenic factors of local immunoreactions are important agents in the development ... | 1999-09-01 |
10467688 | Endometriosis and infertility are frequently associated. There is controversy in the literature about the causal correlation. There is no doubt, that progressed disease causes infertility by mechanical disturbances of the reproductive organs. Mild and moderate endometriosis however is discussed to cause functional infe... | 1999-09-01 |
10467689 | Endometriosis is a proliferative disease, which is often diagnosed with delay. Laparoscopy and histology are necessary for diagnosis. Different factors influence the success of therapy. Proliferative markers are very important for the differential diagnosis of active and inactive endometriosis. In a study it could be s... | 1999-09-01 |
10467690 | A total of 94 pre- or peri-menopausal patients from eight centres with intractable uterine bleedings and completed family planning were assessed as part of a clinical trial on the use of leuprorelin acetate monthly depot prior to endometrial ablation. The primary target criterion was flattening of the endometrium after... | 1999-09-01 |
10467691 | GnRH agonist (GnRHa) administered for 6 months leads to an effective desensitisation of the pituitary and hypoestrogenism without exerting a particular effect on the whole metabolism. At the end of the first month's a suppression of the serum estradiol levels are achieved, the level of LH and FSH decline in the hypogon... | 1999-09-01 |
10467692 | In a European, randomised Phase III trial, we studied ovarian ablation using a GnRH-agonist (leuprorelin acetate 3M depot, Takeda Pharma GmbH, Aachen) with CMF combination chemotherapy in pre- and peri-menopausal, hormone receptor-positive patients with involvement of 1-9 axillary lymph nodes. All planned 600 patients ... | 1999-09-01 |
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Date: June 16, 2025
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