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22653314
CONCLUSION: This analysis provides a current evidence-based estimate of PACG prevalence in European derived populations and suggests there are 130,000 people in the UK, 1.60 million people in Europe and 581,000 people in the USA with PACG today. Accounting for ageing population structures, cases are predicted to increa...
PURPOSE: Primarily to determine the prevalence of various types of glaucoma and ocular hypertension in Wroclaw inhabitants aged 40-79 years. The second aim of the study was to determine the number of undiagnosed glaucoma cases in this population. METHODS: A representative group of the Wroclaw population (4853 people ag...
[ { "source_pmid": "16283988", "source_text": "PURPOSE: Primarily to determine the prevalence of various types of glaucoma and ocular hypertension in Wroclaw inhabitants aged 40-79 years. The second aim of the study was to determine the number of undiagnosed glaucoma cases in this population.\nMETHODS: A repr...
20665044
CONCLUSIONS: Current data suggests that IVB is an effective short-term treatment for diabetic macular edema, and that its efficacy wanes after 6 weeks. More trials exploring the therapeutic role of intravitreal bevacizumab in DME need to be conducted to define the role of bevacizumab.
OBJECTIVE: To provide data on the short-term effect of intravitreal bevacizumab for diabetic macular edema (DME). DESIGN: Randomized phase II clinical trial. PARTICIPANTS: One hundred twenty-one eyes of 121 subjects (109 eligible for analysis) with DME and Snellen acuity equivalent ranging from 20/32 to 20/320. INTERVE...
[ { "source_pmid": "17698196", "source_text": "OBJECTIVE: To provide data on the short-term effect of intravitreal bevacizumab for diabetic macular edema (DME).\nDESIGN: Randomized phase II clinical trial.\nPARTICIPANTS: One hundred twenty-one eyes of 121 subjects (109 eligible for analysis) with DME and Snel...
23741296
CONCLUSION: Ex-Press was associated with equivalent efficacy to Trab in lowering IOP. Comparable proportions of patients reached the IOP target with Ex-Press and Trab. Ex-Press was better tolerated than Trab.
INTRODUCTION: The purpose of this study was to establish the efficacy and safety of the Ex-PRESS (Optonol Ltd., Neve Ilan, Israel) mini glaucoma shunt in open-angle glaucoma. METHODS: This was a prospective, randomized trial. Eyes from enrolled patients were randomly assigned to either Ex-PRESS implantation under a scl...
[ { "source_pmid": "19337705", "source_text": "INTRODUCTION: The purpose of this study was to establish the efficacy and safety of the Ex-PRESS (Optonol Ltd., Neve Ilan, Israel) mini glaucoma shunt in open-angle glaucoma.\nMETHODS: This was a prospective, randomized trial. Eyes from enrolled patients were ran...
27846316
CONCLUSION: The current literature suggests a possible association between GC use and the development of cataract. However, this risk cannot be accurately quantified in RA from the available evidence. RCTs have not adequately captured these outcomes and well-designed observational research is required.
OBJECTIVE: To assess the effect of 5 mg/day prednisolone on disease progression in patients with early rheumatoid arthritis (RA) receiving standardized disease-modifying antirheumatic drug (DMARD) therapy. METHODS: Patients with active RA of <2 years' duration were randomly assigned in a double-blinded manner to receiv...
[ { "source_pmid": "16255011", "source_text": "OBJECTIVE: To assess the effect of 5 mg/day prednisolone on disease progression in patients with early rheumatoid arthritis (RA) receiving standardized disease-modifying antirheumatic drug (DMARD) therapy.\nMETHODS: Patients with active RA of <2 years' duration w...
30030923
This meta-analysis strongly suggests improved VA outcomes at 12 months in patients with wet AMD for 2.0 mg aflibercept, comparable to but slightly lower than landmark trials. Increased injection frequency and younger age demonstrates a trend with improved outcomes.
PURPOSE: To study visual outcome and number of annual injections in treatment-naïve patients with neovascular age-related macular degeneration (nAMD) before and after a change in first-line therapy from ranibizumab to aflibercept in a high-volume clinical practice. METHODS: This was a retrospective chart review of rout...
[ { "source_pmid": "27535819", "source_text": "PURPOSE: To study visual outcome and number of annual injections in treatment-naïve patients with neovascular age-related macular degeneration (nAMD) before and after a change in first-line therapy from ranibizumab to aflibercept in a high-volume clinical practic...
26625212
AUTHORS' CONCLUSIONS: Overall, the use of devices with standard trabeculectomy may help with greater IOP reduction at one-year follow-up than trabeculectomy alone; however, due to potential biases and imprecision in effect estimates, the quality of evidence is low. When we examined outcomes within subgroups based on th...
INTRODUCTION: The purpose of this study was to establish the efficacy and safety of the Ex-PRESS (Optonol Ltd., Neve Ilan, Israel) mini glaucoma shunt in open-angle glaucoma. METHODS: This was a prospective, randomized trial. Eyes from enrolled patients were randomly assigned to either Ex-PRESS implantation under a scl...
[ { "source_pmid": "19337705", "source_text": "INTRODUCTION: The purpose of this study was to establish the efficacy and safety of the Ex-PRESS (Optonol Ltd., Neve Ilan, Israel) mini glaucoma shunt in open-angle glaucoma.\nMETHODS: This was a prospective, randomized trial. Eyes from enrolled patients were ran...
20179632
"CONCLUSIONS: Trabeculectomy was found to have a greater pressure-lowering effect compared with visc(...TRUNCATED)
"AIMS: To compare trabeculectomy with viscocanalostomy augmented with adjunctive antimetabolite use (...TRUNCATED)
[{"source_pmid":"15258016","source_text":"AIMS: To compare trabeculectomy with viscocanalostomy augm(...TRUNCATED)
30666092
"Compared with ranibizumab, corticosteroid implant did not have greater improved BCVA, but corticost(...TRUNCATED)
"PURPOSE: To evaluate whether treatment with dexamethasone intravitreal implant (DEX implant) 0.7 m(...TRUNCATED)
[{"source_pmid":"27632215","source_text":"PURPOSE: To evaluate whether treatment with dexamethasone (...TRUNCATED)
32504495
"State-of-the-art neural networks could effectively detect clinical significant DR. To further impro(...TRUNCATED)
"IMPORTANCE: More than 60 million people in India have diabetes and are at risk for diabetic retinop(...TRUNCATED)
[{"source_pmid":"31194246","source_text":"IMPORTANCE: More than 60 million people in India have diab(...TRUNCATED)
26966358
"CONCLUSION: This meta-analysis suggests lower cognitive function test scores in patients with AMD, (...TRUNCATED)
"Several previous studies showed that age-related macular degeneration (AMD) and Alzheimer's disease(...TRUNCATED)
[{"source_pmid":"24370621","source_text":"Several previous studies showed that age-related macular d(...TRUNCATED)
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