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Fractionation and release of Cd, Cu, Pb, Mn, and Zn from historically contaminated river sediment in Southern China: Effect of time and pH.
The release of in situ heavy metals (cadmium [Cd], copper [Cu], lead [Pb], manganese [Mn], and zinc [Zn]) from contaminated river sediment near a Cu-iron mine in South China was experimentally studied. The effects of pH values and the kinetics of heavy metal release were investigated. In addition, species of the 5 meta...
Fractionation;Heavy metals;Release kinetics;Sediment;pH
pubmed
FABP4 silencing ameliorates hypoxia reoxygenation injury through the attenuation of endoplasmic reticulum stress-mediated apoptosis by activating PI3K/Akt pathway.
Endoplasmic reticulum (ER) stress and subsequent apoptosis play a vital role in myocardial ischemia reperfusion (IR) injury. Fatty acid binding protein 4 (FABP4) may induce ER stress. The aim of this study was to investigate the mechanism and effect of FABP4 on IR injury in vitro. Rat H9c2 cells were exposed to hypoxia...
Apoptosis;Endoplasmic reticulum stress;FABP4;Hypoxia reoxygenation;PI3K/Akt
pubmed
Appropriateness of initial dose of non-vitamin K antagonist oral anticoagulants in patients with non-valvular atrial fibrillation in the UK.
To evaluate the appropriateness of the initial prescribed daily dose of non-vitamin K antagonist oral anticoagulants (NOACs) according to label in patients with non-valvular atrial fibrillation (NVAF) in the UK. Population-based cross-sectional study. UK primary care. 30 467 patients with NVAF and a first prescription ...
Cardiac Epidemiology;EPIDEMIOLOGY;Thromboembolism
pubmed
Assessment of diets containing curcumin, epigallocatechin-3-gallate, docosahexaenoic acid and α-lipoic acid on amyloid load and inflammation in a male transgenic mouse model of Alzheimer's disease: Are combinations more effective?
Increasingly, evidence is accumulating pointing at a protective role of a healthy diet at decreasing the risk of Alzheimer's disease. To test the effectiveness of nutritional components, the following food-derived compounds: curcumin alone (curcumin), curcumin combined with (-)epigallocatechin-3-gallate (EGCG), docosah...
Amyloid plaque;Curcumin;Fish oil;Green tea;Inflammation;Lipoic acid;Microglia
pubmed
Combining Wireless Technology and Behavioral Economics to Engage Patients (WiBEEP) with cardiometabolic disease: a pilot study.
The long-term management of cardiometabolic diseases, such as type 2 diabetes and hypertension, is complex and can be facilitated by supporting patient-directed behavioral changes. The concurrent application of wireless technology and personalized text messages (PTMs) based on behavioral economics in managing cardiomet...
Blood pressure;Diabetes;Diet;Exercise;Text messages
pubmed
Can the gut be the missing piece in uncovering PD pathogenesis?
It is now well established that Parkinson's disease (PD) is not only a movement disorder of the CNS but also a gastrointestinal disorder affecting the enteric nervous system (ENS). The gut-brain axis is a bidirectional communication between the brain and the gastrointestinal tract, which comprises besides the CNS and t...
Enteric nervous system;Gut microbiota;Gut-brain axis;Inflammation;Intestinal epithelial barrier;Parkinson's disease
pubmed
Low partner testing in high HIV prevalence setting in Freetown, Sierra Leone: a retrospective study.
Despite a 1.5% National HIV prevalence, less than 40% of people living with HIV in Sierra Leone know their status. Limited activities on testing partners of HIV patients could be contributory to this substantial unawareness of HIV status. We carried out a retrospective study aimed at assessing partner testing and HIV p...
Clients;Connaught Hospital;Counselling;Provider
pubmed
Two new species of Batoctenus Sharp (Coleoptera: Staphylinidae: Pselaphinae) from French Guiana.
Two new species of the Neotropical pselaphine genus Batoctenus Sharp, 1887 are described from French Guiana, i.e., B. kawmontis sp. nov., and B. kociani sp. nov., with their habitus and major diagnostic characters illustrated.
Coleoptera, taxonomy, Batrisini, Batoctenus, new species, Neotropical region
pubmed
Clinical outcome and toxicity after simultaneous integrated boost IMRT in head and neck squamous cell cancer patients.
A simultaneous integrated boost (SIB) intensity modulated radiotherapy (IMRT) in patients with head and neck squamous cell carcinoma (HNSCC) allows to irradiate different target volumes to different dose levels within a single treatment session without increasing the toxicity. To analyze the outcome and toxicity of pat...
Head and neck cancer;IMRT;Outcome;Radiotherapy;Simultaneous integrated boost;Squamous cell carcinoma
pubmed
Functional transepithelial transport measurements to detect nephrotoxicity in vitro using the RPTEC/TERT1 cell line.
The kidney is a frequent target for organ-specific toxicity as a result of its primary function in controlling body fluids, for example, via resorption of amino acids, peptides, nutrients, ions, xenobiotics and water from the primary urine as well as excretion of metabolic waste products and hydrophilic and amphiphilic...
Epithelial transport;In vitro;Kidney;Nephrotoxicity;Proximal tubule
pubmed
Direct Feature Evaluation in Black-Box Optimization Using Problem Transformations.
Exploratory Landscape Analysis provides sample-based methods to calculate features of black-box optimization problems in a quantitative and measurable way. Many problem features have been proposed in the literature in an attempt to provide insights into the structure of problem landscapes and to use in selecting an eff...
ANOVA;Black-box optimization;ELA features;evaluation criteria;linearity;neutrality;problem transformations;ruggedness;sample size.
pubmed
Liddle's syndrome mechanisms, diagnosis and management.
Liddle's syndrome is a genetic disorder characterized by hypertension with hypokalemic metabolic alkalosis, hyporeninemia and suppressed aldosterone secretion that often appears early in life. It results from inappropriately elevated sodium reabsorption in the distal nephron. Liddle's syndrome is caused by mutations to...
ENaC;Liddle’s syndrome;blood pressure;distal nephron;hypertension
pubmed
Hypertension and Cardiovascular Morbidity Following Surgery for Kidney Cancer.
Despite better renal function following nephron-sparing surgery (NSS) relative to radical nephrectomy (RN), there is no consensus with respect to the long-term sequelae associated with surgery. To investigate the effect of surgery and the temporal pattern of two different cardiovascular event (CVe) categories after NSS...
Cardiovascular events;Hypertension;Kidney cancer;Partial nephrectomy;Radical nephrectomy;Renal cancer
pubmed
Convergence of human and Old World monkey gut microbiomes demonstrates the importance of human ecology over phylogeny.
Comparative data from non-human primates provide insight into the processes that shaped the evolution of the human gut microbiome and highlight microbiome traits that differentiate humans from other primates. Here, in an effort to improve our understanding of the human microbiome, we compare gut microbiome composition ...
Cercopithecine;Human evolution;Human gut microbiome;Primate gut microbiome
pubmed
The interplay between substance use and intimate partner violence perpetration: A meta-ethnography.
The relationship between intimate partner violence (IPV) perpetration and substance use is not well understood. We conducted a meta-ethnography of qualitative studies to explore how substance use features in survivors' and perpetrators' accounts of IPV perpetration. Qualitative studies from 1995 to 2016 were identified...
Alcohol;Intimate partner violence;Meta-ethnography;Perpetrator;Qualitative research;Substance use;Survivor;Victim
pubmed
Relation between adaptive function and IQ among youth with histories of heavy prenatal alcohol exposure.
Adaptive function and general intellectual function are two important and often correlated domains. While youth with prenatal alcohol exposure frequently demonstrate impairments in both domains, it is not clear whether the relation between these domains is consistent across levels of ability or whether, for example, ad...
adaptive function;fetal alcohol spectrum disorders (FASD);fetal alcohol syndrome (FAS);intellectual functioning
pubmed
Clinical retrospective analysis of long-pulsed 1064-nm Nd:YAG laser in the treatment of onychomycosis and its effect on the ultrastructure of fungus pathogen.
The objective of this study was to analyze retrospectively the clinical efficacy and fungal clearance of long-pulsed 1064-nm Nd:YAG laser for treating onychomycosis and explore the inhibitory effects of laser on the fungus pathogen-induced onychomycosis in vitro. We performed a systematic retrospective analysis of clin...
Electron microscopy;Irradiation;Long-pulsed 1064-nm Nd:YAG laser;Onychomycosis;Trichophyton mentagrophytes;Trichophyton rubrum
pubmed
Factors Associated with Mammographic Density in Postmenopausal Women.
Breast density increases the risk of breast cancer, but also in the interpretation of mammography is also important. This study examine the risk factors affecting breast density in postmenopausal women. Between January 2013 and January 2014, 215 patients admitted to The Clinics of Gynecology and Obstetrics with complai...
Mammary glands human;Mammography;Postmenopause
pubmed
A proton current associated with sour taste: distribution and functional properties.
Sour taste is detected by taste receptor cells that respond to acids through yet poorly understood mechanisms. The cells that detect sour express the protein PKD2L1, which is not the sour receptor but nonetheless serves as a useful marker for sour cells. By use of mice in which the PKD2L1 promoter drives expression of ...
PKD2L1;acid;ion channel;pH;sensory transduction
pubmed
Pathogenesis of cerebral malaria: new diagnostic tools, biomarkers, and therapeutic approaches.
Cerebral malaria is a severe neuropathological complication of Plasmodium falciparum infection. It results in high mortality and post-recovery neuro-cognitive disorders in children, even after appropriate treatment with effective anti-parasitic drugs. While the complete landscape of the pathogenesis of cerebral malaria...
Plasmodium falciparum;cerebral malaria;diagnostic;new therapies;pathophysiology;research tools
pubmed
Larvicidal activity of catechin isolated from Leucas aspera against Aedes aegypti, Anopheles stephensi, and Culex quinquefasciatus (Diptera: Culicidae).
Vector control is facing a threat due to the emergence of resistance to synthetic insecticides. Insecticides of plant origin my serve as an alternative biocontrol technique in the future. The aim of the present study was to evaluate the larvicidal activity of fractions and compounds from the whole-plant methanol extrac...
Aedes aegypti;Anopheles stephensi;Catechin;Culex quinquefasciatus;Larvicidal activity;Leucas aspera
pubmed
Prediction of the thickness of the compensator filter in radiation therapy using computational intelligence.
In this study, artificial neural networks (ANNs) and adaptive neuro-fuzzy inference system (ANFIS) are investigated to predict the thickness of the compensator filter in radiation therapy. In the proposed models, the input parameters are field size (S), off-axis distance, and relative dose (D/D0), and the output is the...
Computational intelligence;Filter in radiation therapy;Radiation therapy;Thickness of the compensator
pubmed
Higher breastfeeding performance index is associated with lower risk of illness in infants under six months in Ethiopia.
Breastfeeding performance index is an explanatory attempt to summarize key breastfeeding practices by summarizing the different dimensions of breastfeeding practices into a single summary variable. Breastfeeding performance index is used to assess optimal breastfeeding practices by constructing a single composite index...
Breastfeeding;DHS;Ethiopia;Index;Infants
pubmed
Crystal structure of 1-(2-amino-phen-yl)-3-phenyl-urea.
In the title compound, C13H13N3O, the phenyl ring makes a dihedral angle of 47.0 (1)° with the mean plane of the -NC(=O)N- unit, while the dihedral angle between the latter mean plane and the amino-phenyl ring is 84.43 (7)°. In the crystal, mol-ecules are linked via N-H⋯O hydrogen bonds involving the central -NHC(=O)NH...
N—H⋯N hydrogen bonds;N—H⋯O hydrogen bonds;crystal structure;twinned structure;urea derivatives
pubmed
A dual-valve system to minimize loss of pneumoperitoneum in laparoscopic surgery.
Loss of visualization of the surgical field due to pneumoperitoneum deflation when CO2 insufflator cylinders become empty can occur at key moments during laparoscopic surgery. The purpose of this study was to examine the incidence of intraoperative cylinder exhaustion in the United Kingdom, determine its impact on pati...
CO2 cylinder exchange;Loss of insufflation
pubmed
Fall risk is associated with amplified functional connectivity of the central executive network in patients with Parkinson's disease.
Falls are debilitating problems that markedly impact the health-related quality of life of many patients with Parkinson's disease (PD). Numerous studies point to the role of executive function and attention in falls; however, the brain mechanisms underlying these relationships are less clear. Here, we aim to evaluate t...
Caudate;Central executive network;Falls;Function connectivity;Parkinson’s disease
pubmed
Causes and consequences of habitat fragmentation in river networks.
Increases in river fragmentation globally threaten freshwater biodiversity. Rivers are fragmented by many agents, both natural and anthropogenic. We review the distribution and frequency of these major agents, along with their effects on connectivity and habitat quality. Most fragmentation research has focused on terre...
barrier;biodiversity;connectivity;defragmentation;edge effect;matrix permeability
pubmed
Amnesia in an actor: Learning and re-learning of play passages despite severe autobiographical amnesia.
We describe the case of an accomplished actor, whom we term AB, who suffered severe amnesia following a cardiac arrest and hypoxic brain damage, affecting medial temporal and thalamic structures. His performance on standard episodic memory tests, and on measures of retrograde amnesia, including autobiographical memory,...
Actor;Autobiographical amnesia;Episodic memory;Semantic learning
pubmed
Relationship between echocardiographic and cardiac magnetic resonance imaging-derived measures of right ventricular function in patients with chronic thromboembolic pulmonary hypertension.
Echocardiography is widely used to evaluate right ventricular (RV) function. However, the value of echocardiographic parameters to assess RV function in patients with chronic thromboembolic pulmonary hypertension (CTEPH) is unknown. In this study, we analyzed the correlations between echocardiographic parameters and th...
CMR;chronic thromboembolic pulmonary hypertension;echocardiography;right ventricular function
pubmed
The growth of computer-assisted (robotic) surgery in urology 2000-2014: The role of Asian surgeons.
A major role in the establishment of computer-assisted robotic surgery (CARS) can be traced to the work of Mani Menon at Vattikuti Urology Institute (VUI), and of many surgeons of Asian origin. The success of robotic surgery in urology has spurred its acceptance in other surgical disciplines, improving patient comfort ...
Asian;IDEAL;Kidney transplant;Nephrectomy;Radical cystectomy;Radical prostatectomy;Reconstructive urology;Robotic surgery
pubmed
Stressful life events and leukocyte telomere attrition in adulthood: a prospective population-based cohort study.
Telomere attrition might be one of the mechanisms through which psychosocial stress leads to somatic disease. To date it is unknown if exposure to adverse life events in adulthood is associated with telomere shortening prospectively. In the current study we investigated whether life events are associated with shortenin...
Adversity;life events;observational cohort study;prospective;stress;telomere
pubmed
Structural characterization and anti-tumor activity of polysaccharide produced by Hirsutella sinensis.
HSP-III, a novel homogeneous polysaccharide with 513.89 kDa molecular weight, was fractionated from submerged cultures of Hirsutella sinensis by Sevag and chromatography on Sephadex G-100 column. The total sugar content of HSP-III was amounted to 89.87%. Based on the results of high performance gel permeation chromatog...
Anti-tumor activity;Polysaccharide;Structure
pubmed
Complete annotated genome sequence of Mycobacterium tuberculosis (Zopf) Lehmann and Neumann (ATCC35812) (Kurono).
We report the completely annotated genome sequence of Mycobacterium tuberculosis (Zopf) Lehmann and Neumann (ATCC35812) (Kurono), which is a used for virulence and/or immunization studies. The complete genome sequence of M. tuberculosis Kurono was determined with a length of 4,415,078 bp and a G+C content of 65.60%. Th...
Complete genome;Kurono;PE-PPE;PacBio sequencer;Phyrogenetic tree
pubmed
Adverse childhood experiences and substance use among Hispanic emerging adults in Southern California.
Emerging adults who experienced stressful childhoods may engage in substance use as a maladaptive coping strategy. Given the collectivistic values Hispanics encounter growing up, adverse childhood experiences may play a prominent role in substance use decisions as these events violate the assumptions of group oriented ...
Adverse childhood experiences;Emerging adults;Hispanics;Prevention;Substance use;Young adults
pubmed
Sodium bicarbonate ingestion augments the increase in PGC-1α mRNA expression during recovery from intense interval exercise in human skeletal muscle.
We tested the hypothesis that ingestion of sodium bicarbonate (NaHCO3) prior to an acute session of high-intensity interval training (HIIT) would augment signaling cascades and gene expression linked to mitochondrial biogenesis in human skeletal muscle. On two occasions separated by ∼1 wk, nine men (mean ± SD: age 22 ±...
glycogen;high-intensity interval training;mitochondria;supplementation
pubmed
Glucagon-like polypeptide agonists in type 2 diabetes mellitus: efficacy and tolerability, a balance.
Glucagon-like polypeptide (GLP-1) receptor agonist treatment has multiple effects on glucose metabolism, supports the β cell, and promotes weight loss. There are now five GLP-1 agonists in clinical use with more in development. GLP-1 treatment typically can induce a lowering of hemoglobin A1c (HbA1c) of 0.5-1.5% over t...
albiglutide;dulaglutide;exenatide;liraglutide;lixisenatide
pubmed
Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73.
We describe a novel nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum among 30 children (ages 1.0 to 28 years) from diverse Amish demes. Children with nephrocerebellar syndrome had progressive microcephaly, visual impairment, stagnant psychomotor development, abnormal extrapyramidal movements and nephro...
cerebellar hypoplasia;mTOR;mitosis;nephrosis;progressive microcephaly
pubmed
The prehospital management of traumatic brain injury.
Traumatic brain injury (TBI) is an important cause of death and disability, particularly in younger populations. The prehospital evaluation and management of TBI is a vital link between insult and definitive care and can have dramatic implications for subsequent morbidity. Following a TBI the brain is at high risk for ...
Airway management;emergency medical services;traumatic brain injury
pubmed
Bile acid accelerates erbB2-induced pro-tumorigenic activities in biliary tract cancer.
Although very few studies have addressed the molecular and cellular mechanisms underlying the development of biliary tract cancer (BTC), several lines of evidence suggest a role for the erbB receptor family. Overexpression and activation of erbB2 has been reported in a significant percentage of human BTC. Further, we p...
bile acid;biliary tract cancer;erbB2
pubmed
The value of forceps biopsy and core needle biopsy in prediction of pathologic complete remission in locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy.
Patients with pathological complete remission (pCR) after treated with neoadjuvant chemoradiotherapy (nCRT) have better long-term outcome and may receive conservative treatments in locally advanced rectal cancer (LARC). The study aimed to evaluate the value of forceps biopsy and core needle biopsy in prediction of pCR ...
core needle biopsy;forceps biopsy;locally advanced rectal cancer;neoadjuvant chemoradiotherapy
pubmed
Heart failure patients' descriptions of participation in structured home care.
To strengthen the patient's position in health care, patient participation has been decreed in policy documents and legalizations. For patients suffering from heart failure, self-care is an important part of disease management and participation is crucial to succeed with this. To examine how heart failure patients rece...
decision making;heart failure;home care;involvement;patient participation;qualitative method
pubmed
Evaluation of hydrogel matrices for vessel bioplotting: Vascular cell growth and viability.
Developing matrices biocompatible with vascular cells is one of the most challenging tasks in tissue engineering. Here, we compared the growth of vascular cells on different hydrogels as potential materials for bioplotting of vascular tissue. Formulations containing alginate solution (Alg, 2%, w/v) blended with protein...
alginate-protein hydrogels;biocompatibility;fibroblasts;scaffold endothelialisation;smooth muscle cells
pubmed
From Clinical Misdiagnosis to Electrophysiological Diagnosis: Two Male Asystole Cases.
Differential diagnosis of epilepsy and syncope may be difficult. Arrhythmias such as asystole, or ventricular fibrillation, may lead to cerebral hypoperfusion mimicking partial or secondary generalized tonic-clonic seizures. While performing an electroencephalogram (EEG) for epilepsy diagnosis, simultaneous electrocard...
EEG;asystole;diagnosis;epilepsy;syncope
pubmed
Influence of natural zeolite and nitrification inhibitor on organics degradation and nitrogen transformation during sludge composting.
Sludge composting is one of the most widely used treatments for sewage sludge resource utilization. Natural zeolite and nitrification inhibitor (NI) are widely used during composting and land application for nitrogen conservation, respectively. Three composting reactors (A--the control, B--natural zeolite addition, and...
3,4-Dimethylpyrazole phosphate (DMPP);Composting;Natural zeolite;Nitrification inhibitor (NI);Nitrogen transformation functional genes;Sewage sludge
pubmed
Clinical manifestations of pneumonia according to the causative organism in patients in the intensive care unit.
Whether the causative organism influences the clinical course of pneumonia in the intensive care unit (ICU) is controversial. We assessed the clinical manifestations and prognosis of pneumonia according to the causative pathogens in patients in a medical ICU. A retrospective observational study was performed in a medic...
Drug resistance, multiple;Intensive care units;Pathogenicity;Pneumonia
pubmed
The urothelium of a hibernator: the American black bear.
The American black bear undergoes a 3-5 month winter hibernation during which time bears do not eat, drink, defecate, or urinate. During hibernation renal function (GFR) is 16-50% of normal but urine is reabsorbed across the urinary bladder (UB) urothelium thus enabling metabolic recycling of all urinary constituents. ...
Black bear;hibernation;urinary bladder microscopy;urine reabsorption;urothelium
pubmed
Nurses' and personal care assistants' role in improving the relocation of older people into nursing homes.
This article presents findings from a study that explored nurses' and personal care assistants' role in improving the relocation of older people into a nursing home. Suggestions for improving the relocation process for older people moving into a nursing home have been the outcomes of studies that have interviewed resid...
aged care;aged care facilities;enrolled nurses;nursing homes;older people;personal care assistants;registered nurses;relocation
pubmed
Improved Bacterial 16S rRNA Gene (V4 and V4-5) and Fungal Internal Transcribed Spacer Marker Gene Primers for Microbial Community Surveys.
Designing primers for PCR-based taxonomic surveys that amplify a broad range of phylotypes in varied community samples is a difficult challenge, and the comparability of data sets amplified with varied primers requires attention. Here, we examined the performance of modified 16S rRNA gene and internal transcribed space...
16S;ITS;marker genes;microbial ecology;primers
pubmed
Chokeberry attenuates the expression of genes related to de novo lipogenesis in the hepatocytes of mice with nonalcoholic fatty liver disease.
Nonalcoholic fatty liver disease (NAFLD), which is characterized by steatosis, is a major public health concern. Previous studies have shown that chokeberry has anti-inflammatory, antimutagenic, hepatoprotective, cardioprotective, and antidiabetic effects. In this study, we hypothesized that chokeberry powder can atten...
Aronia melanocarpa;Chokeberry;De novo lipogenesis;High-fat diet;Lipid metabolism;Nonalcoholic fatty liver disease
pubmed
Enamel matrix derivative, inflammation and soft tissue wound healing.
Over 15 years have now passed since enamel matrix derivative (EMD) emerged as an agent capable of periodontal regeneration. Following thorough investigation, evidenced-based clinical application is now established for a multitude of clinical settings to promote regeneration of periodontal hard tissues. Despite the larg...
Emdogain;enamel matrix proteins;inflammation;periodontal regeneration;periodontal wound healing
pubmed
P < 5 × 10(-8) has emerged as a standard of statistical significance for genome-wide association studies.
In genome-wide association studies (GWASs), the practice regarding the choice of thresholds of significance and of thresholds used to include single nucleotide polymorphisms (SNPs) in a further validation stage is not well known. Here, we performed a systematic analysis of all GWASs published in two recent but nonconse...
Evaluation studies as topic;False discovery rate;Genome-wide association study;Multiple testing;Significance thresholds;Validation studies
pubmed
Impact of regional femoral nerve block during general anesthesia for hip arthoplasty on blood pressure, heart rate and pain control: A randomized controlled study.
Adequate pain management is essential for preventing hemodynamic instability which can affect the perfusion of vital organs during the perioperative period, particularly in geriatric patients. For hip arthroplasty, peripheral nerve block is frequently used, limiting the adverse effects of opioid and non-opioid analgesi...
Femoral nerve block;hemodynamic control;hip arthroplasty;postoperative analgesics
pubmed
Co-operative intermolecular kinetics of 2-oxoglutarate dependent dioxygenases may be essential for system-level regulation of plant cell physiology.
Can the stimulus-driven synergistic association of 2-oxoglutarate dependent dioxygenases be influenced by the kinetic parameters of binding and catalysis?In this manuscript, I posit that these indices are necessary and specific for a particular stimulus, and are key determinants of a dynamic clustering that may functio...
2-oxoglutarate;co-operative kinetics;facial triad;iron deficiency;non-linear regression;system-level
pubmed
Learning curve for endoscopic submucosal dissection of esophageal neoplasms.
There is a significant learning curve for endoscopic submucosal dissection of esophageal neoplasms that has not been fully characterized. This retrospective study included 33 consecutive superficial esophageal neoplasms for analysis of the learning curve for esophageal endoscopic submucosal dissection based on a single...
endoscopic submucosal dissection;learning curve;superficial esophageal neoplasm
pubmed
Situational analysis and future directions of AYUSH: An assessment through 5-year plans of India.
AYUSH is an acronym for Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy. These are the six indigenous systems of medicine practiced in India. A department called Department of Indian System of medicine was created in March 1995 and renamed to AYUSH in November 2003 with a focus to provide increased attent...
Ancient medical manuscripts;Indian systems of medicine;Indian systems of medicine informatics;Sidha and Homeopathy;Unani;Yoga and Naturopathy;mainstreaming of Ayurveda;medical tourism
pubmed
The Tolerance and Accumulation of Miscanthus Sacchariflorus (maxim.) Benth., an Energy Plant Species, to Cadmium.
Miscanthus sacchariflorus (Maxim.) Benth. is a metallophyte suitable for the phytoremediation of mine wastes. The tolerance and accumulation of M. sacchariflorus to cadmium was studied by pot experiments. The results showed that O2·- generation rate, plasma membrane permeability and MDA content of M. sacchariflorus lea...
Miscanthus sacchariflorus (Maxim.) Benth.;cadmium stress;energy plant;phytostabilization;tolerance
pubmed
Population pharmacokinetics of ϵ-aminocaproic acid in adolescents undergoing posterior spinal fusion surgery.
Despite demonstrated efficacy of ϵ-aminocaproic acid (EACA) in reducing blood loss in adolescents undergoing spinal fusion, there are no population-specific pharmacokinetic data to guide dosing. The aim of this study was to determine the pharmacokinetics of EACA in adolescents undergoing spinal fusion surgery and make ...
antifibrinolytic agents;paediatrics;pharmacology;scoliosis;spinal fusion
pubmed
Blockade of Extracellular HMGB1 Suppresses Xenoreactive B Cell Responses and Delays Acute Vascular Xenogeneic Rejection.
Blockade of extracellular high mobility group box 1 (HMGB1) can significantly prolong murine cardiac allograft survival. Here, we determined the role of HMGB1 in xenotransplantation. Sprague-Dawley rat hearts were transplanted heterotopically into BALB/c mice. Xenografts without any treatment developed predominant acut...
Animal models: murine;basic (laboratory) research/science, heart transplantation/cardiology;immunobiology;innate immunity;rejection: vascular;xenoantibody;xenotransplantation
pubmed
Biomarker-based drug safety assessment in the age of systems pharmacology: from foundational to regulatory science.
Improved biomarker-based assessment of drug safety is needed in drug discovery and development as well as regulatory evaluation. However, identifying drug safety-related biomarkers such as genes, proteins, miRNA and single-nucleotide polymorphisms remains a big challenge. The advances of 'omics' and computational techn...
biomarker;drug safety assessment;regulatory science;systems biology;systems pharmacology
pubmed
The effect of thalidomide on ethanol-induced gastric mucosal damage in mice: involvement of inflammatory cytokines and nitric oxide.
Excessive ethanol ingestion causes gastric mucosal damage through the inflammatory and oxidative processes. The present study was aimed to evaluate the protective effect of thalidomide on ethanol-induced gastric mucosal damage in mice. The animals were pretreated with vehicle or thalidomide (30 or 60 mg/kg, orally), an...
Ethanol;Gastric mucosal damage;Inflammation;Nitric oxide;Thalidomide
pubmed
CONTROLLING ANTLER GROWTH IN A CASTRATED INDOCHINESE SIKA DEER CERVUS NIPPON PSEUDAXIS USING A COMMERCIALLY AVAILABLE TRENBOLONE ACETATE AND ESTRADIOL IMPLANT.
A captive Indochinese sika deer (Cervus nippon pseudaxis) was castrated at the age of 5 yr. The resultant abnormal antler growth over the next few years became difficult to manage from both the veterinary and husbandry standpoints. Using a commercially available trenbolone acetate and estradiol implant marketed for dom...
Antler;castrated deer;hormone implant;perruque;sika deer
pubmed
Vertical transmission in experimentally infected sheep despite previous inoculation with Neospora caninum NcNZ1 isolate.
Recent reports indicate N. caninum has a possible role in causing abortions in sheep in New Zealand. Knowledge about the mode of transmission of neosporosis in sheep in New Zealand is limited. This study aimed to determine the rate of vertical transmission that would occur in lambs born from experimentally inoculated e...
Lambs;N. caninum;Sheep;Vertical transmission
pubmed
Triple positive breast cancer: a distinct subtype?
Breast cancer is a heterogeneous disease, and within the HER-2 positive subtype this is highly exemplified by the presence of substantial phenotypical and clinical heterogeneity, mostly related to hormonal receptor (HR) expression. It is well known how HER-2 positivity is commonly associated with a more aggressive tumo...
Anti-HER-2 agents;Breast cancer;Chemotherapy;Hormonal therapy;Triple positive
pubmed
CTLA4-Ig suppresses development of experimental autoimmune uveitis in the induction and effector phases: Comparison with blockade of interleukin-6.
Recently, a number of biologics have been used in the treatment of autoimmune diseases. However, in the treatment of severe autoimmune uveitis, only TNF-alpha inhibitors are preferably used and the effect of other biologics such as interleukin-6 (IL-6) signaling blockade or cytotoxic T-lymphocyte antigen-4-immunoglobul...
Biologic;CTLA4;Cytokine;Experimental autoimmune uveitis;T cell;Uveitis
pubmed
Single pyruvate intake induces blood alkalization and modification of resting metabolism in humans.
Three separate studies were performed with the aim to 1) determine the effect of a single sodium pyruvate intake on the blood acid-base status in males and females; 2) compare the effect of sodium and calcium pyruvate salts and establish their role in the lipolysis rate; and 3) quantify the effect of single pyruvate in...
Acid-base status;Base excess;Blood bicarbonate;Free fatty acids;Glycerol;Respiratory exchange ratio;Resting energy expenditure
pubmed
Clinical outcomes following collagenase injections compared to fasciectomy in the treatment of Dupuytren's contracture.
The aim of this study is to compare the efficacy of collagenase injections with that of fasciectomy in the treatment of Dupuytren's contracture. This is a case-control retrospective study. We reviewed the electronic medical records from January 2009 through January 2013, identifying 142 consecutive patients who underwe...
Collagenase;Dupuytren’s disease;Faciectomy;Finger joint contracture;Xiaflex
pubmed
Effect of minodronate on the speed of sound of the calcaneus in postmenopausal women with an increased risk of fractures: A clinical practice-based observational study.
We previously reported that alendronate and risedronate reduce the urinary levels of cross-linked N-terminal telopeptides of type I collagen (NTX) by 44.9% and 34.7%, respectively, at 3 months after the start of treatment, and increase the speed of sound (SOS) of the calcaneus by 0.6% and 0.65%, respectively, at 12 mon...
bone turnover;minodronate;postmenopausal women;quantitative ultrasound;speed of sound
pubmed
Pentoxifylline as a modulator of anticancer drug doxorubicin. Part I: Reduction of doxorubicin DNA binding.
Pentoxifylline--biologically active aromatic compound--has a well established capability to sequester aromatic ligands, such as an anticancer drug--doxorubicin--in mixed stacking aggregates. Formation of such hetero-complexes may influence biological activity of secluded drug. Presented work shows assessment of pentoxi...
De-intercalation;Hetero-aggregation;Stacking complexes
pubmed
The yeast chromatin remodeler Rsc1-RSC complex is required for transcriptional activation of autophagy-related genes and inhibition of the TORC1 pathway in response to nitrogen starvation.
The yeast RSC, an ATP-dependent chromatin-remodeling complex, is essential for mitotic and meiotic growth. There are two distinct isoforms of this complex defined by the presence of either Rsc1 or Rsc2; however, the functional differences between these complexes are unclear. Here we show that the RSC complex containing...
Autophagy induction;Chromatin remodeling;RSC;Saccharomyces cerevisiae;TORC1
pubmed
How Much In-Kind Support Do Low-Income Nonresident Fathers Provide? A Mixed-Method Analysis.
Past child support research has largely focused on cash payments made through the courts (formal support) or given directly to the mother (informal support), almost to the exclusion of a third type: non-cash goods (in-kind support). Drawing on repeated, semistructured interviews with nearly 400 low-income noncustodial ...
child support;family policy—child-related;low-income families;noncustodial parents
pubmed
Microbial surfactants: fundamentals and applicability in the formulation of nano-sized drug delivery vectors.
Microbial surfactants, so-called biosurfactants, comprise a wide variety of structurally distinct amphipathic molecules produced by several microorganisms. Besides exhibiting surface activity at the interfaces, these molecules present powerful characteristics including high biodegradability, low toxicity and special bi...
Biosurfactants;Drug delivery systems;Microemulsions;Nanoparticles;Self-aggregation
pubmed
Revision of the Massarineae (Pleosporales, Dothideomycetes).
We here taxonomically revise the suborder Massarineae (Pleosporales, Dothideomycetes, Ascomycota). Sequences of SSU and LSU nrDNA and the translation elongation factor 1-alpha gene (tef1) are newly obtained from 106 Massarineae taxa that are phylogenetically analysed along with published sequences of 131 taxa in this s...
Aquastroma Kaz. Tanaka & K. Hiray.;Aquastroma magniostiolata Kaz. Tanaka & K. Hiray.;Aquilomyces rebunensis Kaz. Tanaka & K. Hiray.;Clypeoloculus Kaz. Tanaka & K. Hiray.;Clypeoloculus akitaensis Kaz. Tanaka & K. Hiray.;Clypeoloculus hirosakiensis Kaz. Tanaka & K. Hiray.;Clypeoloculus microsporus Kaz. Tanaka & K. Hiray....
pubmed
Hyperactive RAS/PI3-K/MAPK Signaling Cascade in Migration and Adhesion of Nf1 Haploinsufficient Mesenchymal Stem/Progenitor Cells.
Neurofibromatosis type 1 (NF1) is an autosomal dominant disease caused by mutations in the NF1 tumor suppressor gene, which affect approximately 1 out of 3000 individuals. Patients with NF1 suffer from a range of malignant and nonmalignant manifestations such as plexiform neurofibromas and skeletal abnormalities. We pr...
mesenchymal stem/progenitor cells;neurofibroma;neurofibromatosis 1;oncogene protein p21 (ras)
pubmed
Amadori albumin in diabetic nephropathy.
Nonenzymatic glycation of macromolecules in diabetes mellitus (DM) is accelerated due to persistent hyperglycemia. Reducing sugar such as glucose reacts non enzymatically with free €-amino groups of proteins through series of reactions forming Schiff bases. These bases are converted into Amadori product and further int...
Amadori albumin;diabetic nephropathy;glycated albumin
pubmed
Conductive Inorganic-Organic Hybrid Distributed Bragg Reflectors.
A conductive hybrid distributed Bragg reflector (DBR) is demonstrated, consisting of inorganic and organic semiconductor films and assembled by a thermal deposition technique. A maximum reflectance of 92.2% and a wide spectral width of more than 70 nm are achieved. The hybrid DBR shows good electrical conductivity, whi...
distributed Bragg reflectors;electrical conductivity;inorganic-organic semiconductors
pubmed
Separation of phenolic acids and flavonoids from Trollius chinensis Bunge by high speed counter-current chromatography.
In this work, eleven compounds were successfully separated from Trollius chinensis Bunge by using a two-step high-speed counter-current chromatography (HSCCC) method. NRTL-SAC (nonrandom two-liquid segment activity coefficient) method, a newly developed solvent system selection strategy, was applied to screening the su...
Flavonoids;HSCCC;Phenolic acids;Separation;Trollius chinensis Bunge
pubmed
Antioxidant activity and kinetics studies of eugenol and 6-bromoeugenol.
In this work, we report the antioxidant and free radical scavenging activity of 6-bromoeugenol and eugenol. EC50, the concentration providing 50% inhibition, is calculated and the antioxidant activity index (AAI) is evaluated. The antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-sca...
antioxidant activity;antiradical efficiency;eugenol derivatives;kinetic study
pubmed
Relationship between gene polymorphisms and prostate cancer risk.
To investigate the relationship between genetic factor and prostate cancer (Pca) risk and the possible cause in it. The polymorphisms of cytochrome P450 family 17 (CYPl7) rs743572, p27 V109G and androgen receptor (AR) gene CAG repeat length in peripheral blood from 70 cases and 70 controls were detected through the pol...
Case–control study;LNcap cells;Prostate cancer;p27 V109G polymorphism
pubmed
Comparison of immunosuppressive therapies for IgA nephropathy after tonsillectomy: three-course versus one-course steroid pulse combined with mizoribine.
It has been reported that steroid pulse therapy for IgA nephropathy improves renal prognosis. However, because of the side effects, steroid dose must be restricted to some cases. Treatment effects of steroid on cases already presenting with reduced renal function are unknown. In this study, we performed tonsillectomy i...
IgA nephropathy;Mizoribine;Steroid pulse;Tonsillectomy
pubmed
Diagnostic values for the viral load in peripheral blood mononuclear cells of patients with chronic active Epstein-Barr virus disease.
Chronic active Epstein-Barr virus disease (CAEBV) is a distinct EBV-associated lymphoproliferative disease with a poor prognosis. Although the viral load in blood samples has been widely used for diagnosing CAEBV, well-defined viral load thresholds to guide clinicians are currently lacking. The aim of the present study...
CAEBV;Chronic active Epstein–Barr virus disease;Diagnosis;Peripheral blood mononuclear cells;Viral load
pubmed
Collecting in collections: a PCR strategy and primer set for DNA barcoding of decades-old dried museum specimens.
Natural history museums are vastly underutilized as a source of material for DNA analysis because of perceptions about the limitations of DNA degradation in older specimens. Despite very few exceptions, most DNA barcoding projects, which aim to obtain sequence data from all species, generally use specimens collected sp...
COI;DNA barcodes;DNA sequencing;insect
pubmed
Understanding How Sexual and Gender Minority Stigmas Influence Depression Among Trans Women and Men Who Have Sex with Men in India.
Few studies have assessed how sexual and gender minority stigmas affect the mental health of trans women and self-identified men who have sex with men (MSM) in India, populations with a high HIV burden. We tested whether social support and resilient coping act as mediators of the effect of sexual and gender minority st...
India;depression;gender minority stigma;men who have sex with men;sexual stigma;social support;trans women
pubmed
Validation of a quantitative method to measure neural respiratory drive in children during sleep.
Quantitatively measure and validate analysis of neural respiratory drive (NRD) using a commercial polysomnography system in children during sleep. Surface electromyogram of the diaphragm (sEMGdi) recorded from primary snoring children were analysed. A subset was re-analysed to assess intra- and inter-investigator repro...
Child;Diaphragm EMG;Physiology;Polysomnography;Reproducibility;Sleep
pubmed
Quality of life of patients with locally advanced head and neck cancer treated with induction chemotherapy followed by cisplatin-containing chemoradiotherapy in the Dutch CONDOR study: a randomized controlled trial.
The CONDOR study showed that docetaxel/cisplatin/5-fluorouracil (TPF) followed by conventional radiotherapy with cisplatin 100 mg/m<sup>2</sup> on days 1, 22, and 43 (cis100 + RT; n = 27)) versus accelerated radiotherapy with cisplatin weekly 40 mg/m<sup>2</sup> (cis40 + ART; n = 29) in locally advanced head and neck c...
Chemoradiotherapy;Induction chemotherapy;Locally advanced head and neck cancer;Quality of life;Symptoms
pubmed
Characterization, survival analysis, and expression of IGFR in tumor samples from patients diagnosed with Ewing family tumors treated at the Barretos Cancer Hospital.
Study the clinical characteristics of patients diagnosed with Ewing family tumors (EFTs) and survival analysis based on risk criteria and expression of the surface protein known as insulin-like growth factor (IGFR). This was a retrospective cohort study based on clinical data from 77 patients diagnosed with EFTs treate...
Bone neoplasms;Ewing;Insulin-like growth factor I;Neuroectodermal tumors;Oncology;Peripheral;Primitive;Sarcoma;Survival analysis
pubmed
<i>ALK</i> Fusions in a Wide Variety of Tumor Types Respond to Anti-ALK Targeted Therapy.
Genomic fusions of the anaplastic lymphoma kinase gene (<i>ALK</i>) are a well-established therapy target in non-small cell lung cancer (NSCLC). From a survey of 114,200 clinical cases, we determined the prevalence of <i>ALK</i> rearrangements (r<i>ALK</i>) in non-NSCLC tumors and report their responsiveness to therapi...
ALK;Alectinib;Comprehensive genomic profiling;Crizotinib;Fusion;Rearrangement
pubmed
Chondroprotective activity of N-acetyl phenylalanine glucosamine derivative on knee joint structure and inflammation in a murine model of osteoarthritis.
Osteoarthritis (OA), the most common chronic degenerative joint disease, is characterized by joint structure changes and inflammation, both mediated by the IκB kinase (IKK) signalosome complex. The ability of N-acetyl phenylalanine derivative (NAPA) to increase cartilage matrix components and to reduce inflammatory cyt...
IKKα pathway;Mouse model;NAPA;Osteoarthritis
pubmed
Developing standards for the development of glaucoma virtual clinics using a modified Delphi approach.
To obtain consensus opinion for the development of a standards framework for the development and implementation of virtual clinics for glaucoma monitoring in the UK using a modified Delphi methodology. A modified Delphi technique was used that involved sampling members of the UK Glaucoma and Eire Society (UKEGS). The f...
Delphi;glaucoma;standards;virtual clinic
pubmed
Variation analysis of norovirus among children with diarrhea in rural Hebei Province, north of China.
To understand the distribution of genotyping, as well as evolution of norovirus circulating among children<5yrs., a population-based diarrhea surveillance targeted children<5yrs. was conducted in rural Zhengding County, Hebei Province, China between October 2011 and March 2012. RT-PCR was used to amplify the capsid-enc...
China;Evolutionary rates;Genotyping;Haplotype network;Norovirus;Phylogenetic tree
pubmed
Sphingobacterium corticis sp. nov., isolated from bark of Populus × euramericana.
A Gram-stain negative, aerobic, non-motile bacterial strain, 23D10-4-9<sup>T</sup>, was isolated from symptomatic canker bark tissue of Populus × euramericana. The isolate grew between 4 and 35 °C, with optimal growth occurring at 25 °C. The species was positive for catalase and negative for oxidase activity. Nitrate w...
Populus × euramericana;Sphingobacterium corticis sp. nov.;bark
pubmed
Change-point analysis data of neonatal diffusion tensor MRI in preterm and term-born infants.
The data presented in this article are related to the research article entitled "Mapping the Critical Gestational Age at Birth that Alters Brain Development in Preterm-born Infants using Multi-Modal MRI" (Wu et al., 2017) [1]. Brain immaturity at birth poses critical neurological risks in the preterm-born infants. We u...
Axial diffusivity;Change-point analysis;Neonatal brain MRI;Preterm-born infants;Radial diffusivity
pubmed
Beyond Hygiene: Commensal Microbiota and Allergic Diseases.
Complex communities of microorganisms, termed commensal microbiota, inhabit mucosal surfaces and profoundly influence host physiology as well as occurrence of allergic diseases. Perturbing factors such as the mode of delivery, dietary fibers and antibiotics can influence allergic diseases by altering commensal microbio...
Asthma;Atopic dermatitis;Commensal microbiota;Food allergy
pubmed
The component formula of <i>Salvia miltiorrhiza</i> and <i>Panax</i> ginseng induces apoptosis and inhibits cell invasion and migration through targeting PTEN in lung cancer cells.
Lung cancer still remains the leading cause of cancer-related death worldwide. It is an urgent need for development of novel therapeutic agents to improve current treatment of this disease. Here we investigate whether the effective component formula of traditional Chinese Medicine could serve as new potential therapeut...
PI3K/AKT signaling pathway;PTEN phosphorylation;orthogonal array design;the component formula of Salvia miltiorrhiza and Panax ginseng (FMG)
pubmed
Why georeferencing matters: Introducing a practical protocol to prepare species occurrence records for spatial analysis.
Species Distribution Models (SDMs) are widely used to understand environmental controls on species' ranges and to forecast species range shifts in response to climatic changes. The quality of input data is crucial determinant of the model's accuracy. While museum records can be useful sources of presence data for many ...
GIS;Species Distribution Models;biogeography;botany;georeferencing;herbarium records;museum collections
pubmed
Can gaze-contingent mirror-feedback from unfamiliar faces alter self-recognition?
This study focuses on learning of the self, by examining how human observers update internal representations of their own face. For this purpose, we present a novel gaze-contingent paradigm, in which an onscreen face mimics observers' own eye-gaze behaviour (in the congruent condition), moves its eyes in different dire...
Mirror recognition;Self-face learning;Self-face recognition;Self-face representation
pubmed
A panel of microRNAs can be used to determine oral squamous cell carcinoma.
Subjective histopathology is currently used to diagnose oral squamous cell carcinoma (OSCC). We tested if abundances of a panel of microRNA could be an objective OSCC indicator. Literature review enabled identification of 10 microRNAs associated with oral and head and neck malignancies. We extracted RNA from formalin-f...
algorithm;diagnostic;microRNAs;oral cancer
pubmed
Using the agricultural environment to select better surrogates for foodborne pathogens associated with fresh produce.
Despite continuing efforts to reduce foodborne pathogen contamination of fresh produce, significant outbreaks continue to occur. Identification of appropriate surrogates for foodborne pathogens facilitates relevant research to identify reservoirs and amplifiers of these contaminants in production and processing environ...
Adhesion;Biofilm;E. coli;Environment;Lettuce;Salmonella
pubmed
The influence of DOCA-salt hypertension and chronic administration of the FAAH inhibitor URB597 on K<sub>Ca</sub>2.3/K<sub>Ca</sub>3.1-EDH-type relaxation in rat small mesenteric arteries.
The aim of this study was to examine the influence of deoxycorticosterone acetate-salt (DOCA-salt) hypertension and chronic treatment with the fatty acid amide hydrolase inhibitor, URB597, on small and intermediate conductance calcium-activated potassium channels and endothelium-dependent hyperpolarization (K<sub>Ca</s...
DOCA-salt hypertension;EDH-type relaxation;FAAH inhibitor;K(Ca)2.3;K(Ca)3.1
pubmed
Reversible S<sup>0</sup> /MgS<sub>x</sub> Redox Chemistry in a MgTFSI<sub>2</sub> /MgCl<sub>2</sub> /DME Electrolyte for Rechargeable Mg/S Batteries.
The redox chemistry of magnesium and its application in rechargeable Mg batteries has received increasing attention owing to the unique benefits of Mg metal electrodes, namely high reversibility without dendrite formation, low reduction potentials, and high specific capacities. The Mg/S couple is of particular interest...
batteries;electrochemistry;magnesium;polysulfide;sulfur
pubmed
Whole-Body Docosahexaenoic Acid Synthesis-Secretion Rates in Rats Are Constant across a Large Range of Dietary α-Linolenic Acid Intakes.
Docosahexaenoic acid (DHA) is an ω-3 (n-3) polyunsaturated fatty acid (PUFA) thought to be important for brain function. Although the main dietary source of DHA is fish, DHA can also be synthesized from α-linolenic acid (ALA), which is derived from plants. Enzymes involved in DHA synthesis are also active toward ω-6 (n...
docosahexaenoic acid;kinetics;synthesis;α-linolenic acid;ω-3 PUFA
pubmed
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YAML Metadata Warning:The task_categories "text2text-generation" is not in the official list: text-classification, token-classification, table-question-answering, question-answering, zero-shot-classification, translation, summarization, feature-extraction, text-generation, fill-mask, sentence-similarity, text-to-speech, text-to-audio, automatic-speech-recognition, audio-to-audio, audio-classification, audio-text-to-text, voice-activity-detection, depth-estimation, image-classification, object-detection, image-segmentation, text-to-image, image-to-text, image-to-image, image-to-video, unconditional-image-generation, video-classification, reinforcement-learning, robotics, tabular-classification, tabular-regression, tabular-to-text, table-to-text, multiple-choice, text-ranking, text-retrieval, time-series-forecasting, text-to-video, image-text-to-text, image-text-to-image, image-text-to-video, visual-question-answering, document-question-answering, zero-shot-image-classification, graph-ml, mask-generation, zero-shot-object-detection, text-to-3d, image-to-3d, image-feature-extraction, video-text-to-text, keypoint-detection, visual-document-retrieval, any-to-any, video-to-video, other

SciDocs Keywords exKEYliWORD

Dataset Description

SciDocs2Keywords is a dataset consisting of scientific papers (title and abstract) and their associated author-provided keywords. It is designed for use in task of keyword extraction or abstraction.

Each entry in the dataset includes:

  • Title: The title of the scientific paper.
  • Abstract: A brief summary of the paper.
  • Author Keywords: Keywords provided by the authors to highlight the main topics or concepts of the paper.
  • Source: Paper provider source API.

Associated Model

soon...

How to Use

To use this dataset for model training or evaluation, you can load it using the Hugging Face datasets library as follows:

from datasets import load_dataset

dataset = load_dataset("nicolauduran45/scidocs-keywords-exkeyliword")
print(dataset[0])
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