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Analytical Chemistry
2025_6
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Analytical Chemistry/2025_6.png
D
98
MAC_Bench/ACS/Story/Analytical Chemistry/1987_13.txt
vitg
1987_13.txt
ptamer
MAC_Bench/ACS/Story/Analytical Chemistry/2024_37.txt
clip
2024_37.txt
, wherein we substitute the target-specific antibody with designer DNA nanostructure-based molecular probes for recognizing the SARS-CoV-2 virus via multivalent, pattern-matching interactions.
MAC_Bench/ACS/Story/Analytical Chemistry/2024_45.txt
vith
2024_45.txt
The inclusive droplet digital ELISA (iddELISA) expands the boundaries of digital immunoassays by incorporating all types of bead encapsulations into the analysis, enhancing assay efficiency, and simplifying operations. This innovative approach holds great promise for the early detection of low-abundance biomarkers.
MAC_Bench/ACS/Story/Analytical Chemistry/2025_6.txt
groundtruth
2025_6.txt
train
ACS Energy Letters
2025_2
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS Energy Letters/2025_2.png
B
The cover depicts magnetic couplings between redox-active transition metal centers in typical intercalation-type battery electrodes, which lead to characteristic electron spin and magnetic properties. Such properties can be probed as the battery operates using electron paramagnetic resonance (EPR) and magnetometry and ...
MAC_Bench/ACS/Story/ACS Energy Letters/2020_1.txt
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in situ
MAC_Bench/ACS/Story/ACS Energy Letters/2025_2.txt
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2025_2.txt
Metal halide perovskites are generating enormous excitement for use in both photovoltaic and light-emission applications. The cover art shows the perovskite crystal structure capable of strongly absorbing light to generate electrical power as a solar cell or efficiently generating light emission from electrical power a...
MAC_Bench/ACS/Story/ACS Energy Letters/2017_6.txt
ave_2
2017_6.txt
A collage of perovskite covers featured in previous issues of ACS Energy Letters. To commemorate ten years of perovskite photovoltaics, researchers from around the world tell their own stories and how they became interested in perovskite research. Cover art in the collage appeared on the following covers: Top row, left...
MAC_Bench/ACS/Story/ACS Energy Letters/2019_9.txt
vitg
2019_9.txt
train
Caner Cell
42_7
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Caner Cell/42_7.png
D
On the cover: Defeating a complex disease like cancer will require a united, concerted effort by different types of people from diverse backgrounds who can bring together distinctive experiences and ways of thinking. This issue of Cancer Cell features Voices, Letter, and Commentary pieces discussing the importance of d...
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38_4.txt
On the cover: In this issue of Cancer Cell, Sagnella et al. (pp. 354–370) show that nanocells attack tumors by delivering a cytotoxin and engaging multiple arms of the immune system. The cytotoxin binds and kills tumor cells. Dendritic cells and macrophages engulf dying tumor cells and display tumor-associated antigens...
MAC_Bench/Cell/Story/Caner Cell/37_4.txt
vitg
37_4.txt
On the cover: With the festive red and gold theme of this cover, the Cancer Cell editorial team celebrates the new year and kicks off the celebration of Cancer Cell’s 20th anniversary, which will span 2022 with many exciting articles.
MAC_Bench/Cell/Story/Caner Cell/40_12.txt
vith
40_12.txt
On the cover: Liu et al. reveal the evolutionary dynamics and tumor-immune interplay in acral melanoma (AM). The cover metaphorically represents the progression from AM in situ (AMis) to invasive AM (iAM). AMis tumors (grapes near vines) are homogeneous (green), and iAM close to them are also green, indicating monoclon...
MAC_Bench/Cell/Story/Caner Cell/42_7.txt
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42_7.txt
train
NATURE GENETICS
56_7
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE GENETICS/56_7.png
D
Mendel and memories In celebration of the 200th anniversary of Gregor Mendel’s birth and the 30th anniversary of the launch of Nature Genetics, we look both forwards and backwards at how far the genetics field has come. This cover image is inspired by the cover of the first issue of Nature Genetics in 1992. Image and C...
MAC_Bench/Nature/Story/NATURE GENETICS/54_6.txt
vitg
54_6.txt
Peanut global phenotypic variation Chloroplast and whole-genome sequencing of Arachis accessions sheds light on peanut evolutionary history and phenotypic diversification. See Zheng et al. Image: Nastasic/DigitalVision Vectors/Getty. Cover design: Laoise Mac Gabhann.
MAC_Bench/Nature/Story/NATURE GENETICS/56_4.txt
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56_4.txt
Dynamic single-cell genetic effects A new statistical method known as GASPACHO identifies nonlinear dynamic genetic effects using single-cell RNA-sequencing data. See Kumasaka et al. Image: Alamy. Cover Design: Tulsi Voralia.
MAC_Bench/Nature/Story/NATURE GENETICS/55_7.txt
ave_2
55_7.txt
Engineering crop polyploid genomes Generation of clonal gametes in tomato enables polyploid genome design through controlled combination of pre-defined genome haplotypes. See Wang et al. Image: Rainer Franzen, Yazhong Wang and Rob Kesseler. Cover design: Tulsi Voralia
MAC_Bench/Nature/Story/NATURE GENETICS/56_7.txt
groundtruth
56_7.txt
val
Nature Structural & Molecular Biology
31_11
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Structural & Molecular Biology/31_11.png
C
NSMB’s 30th anniversary To celebrate Nature Structural & Molecular Biology’s 30th anniversary, our cover features original artwork that was submitted by our reader Pedro Rebelo-Guiomar for our cover competition. See Rebelo-Guiomar and Editorial IMAGE CREDIT: Pedro Rebelo-Guiomar, University of Cambridge. COVER DESIGN: ...
MAC_Bench/Nature/Story/Nature Structural & Molecular Biology/31_12.txt
vitg
31_12.txt
Ordered water molecules in respiratory complex I A cryo-EM structure of Y. lipolitica mitochondrial complex I reveals ordered water molecules involved in proton relay and catalysis. See Article by Grba and Hirst Cover Image: Laszlo Podor / Moment / Getty. Cover Design: Erin Dewalt.
MAC_Bench/Nature/Story/Nature Structural & Molecular Biology/27_3.txt
ave_1
27_3.txt
Understanding writers and readers of ubiquitylation In this issue, we feature seven studies that progress our understanding of writers and readers of ubiquitylation, in addition to a Historical Perspective and several Comment pieces reflecting on the ever-expanding roles of this critical modification. See Editorial IMA...
MAC_Bench/Nature/Story/Nature Structural & Molecular Biology/31_11.txt
groundtruth
31_11.txt
Targeting a SARS-CoV-2 pseudoknot A cryo-EM structure of the pseudoknot-forming SARS-CoV-2 frameshift stimulation element guides development of antisense oligonucleotides that impair virus replication. SeeZhang et al. Image:Filip Obr / Alamy Stock Photo. Cover Design: Bethany Vukomanovic
MAC_Bench/Nature/Story/Nature Structural & Molecular Biology/28_4.txt
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28_4.txt
train
Trends in Genetics
41_3
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Genetics/41_3.png
C
Transposable elements comprise a large part of the genome in most organisms. At first thought to serve no beneficial purpose to the host and considered “junk” DNA, recent work has shown these elements to be important players in shaping the genome, often providing benefit to the host. This Special Issue of Trends in Gen...
MAC_Bench/Cell/Story/Trends in Genetics/33_3.txt
ave_2
33_3.txt
In this special issue of Trends in Genetics, we turn the lens on ourselves. The articles this month focus on human genetics, with topics ranging from resources and methods to make the most of the explosion of sequencing data to evolutionary questions about mutation rates and how selection acts through pregnancy.
MAC_Bench/Cell/Story/Trends in Genetics/29_4.txt
vitg
29_4.txt
Sex chromosomes can cause expression imbalances between males and females that are often corrected through dosage compensation. In this issue, Kalita and Keller Valsecchi review our current understanding of dosage compensation across diverse insect species beyond traditional model organisms. They discuss the evolutiona...
MAC_Bench/Cell/Story/Trends in Genetics/41_3.txt
groundtruth
41_3.txt
This Special Issue of Trends in Genetics covers a range of themes related to organogenesis, from the formation of the central nervous system to the evolution of the insect eye. The articles in this issue highlight the commonalities of organ formation that are shared across species and kingdoms, and provide insight on t...
MAC_Bench/Cell/Story/Trends in Genetics/31_7.txt
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31_7.txt
train
ACS Medicinal Chemistry Letters
2025_2
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS Medicinal Chemistry Letters/2025_2.png
A
Preventing the release of the fusion peptide is a challenging approach to target influenza A virus hemagglutinin. This study explores the putative binding site of the pinanamine-containing compound M090. Computational tools were used to examine the feasibility of the binding mode and the structure–activity relationship...
MAC_Bench/ACS/Story/ACS Medicinal Chemistry Letters/2025_2.txt
groundtruth
2025_2.txt
PROTACs: a matter of vector. Two PROTACs based on the same BAZ2A/BAZ2B bromodomain ligand and linker differ only by attachment point to the VHL ligand. Albeit subtle, this difference is crucial: dBAZ2 (blue) degrades both BAZ2A and BAZ2B, while dBAZ2B (orange) is a BAZ2B-selective degrader.
MAC_Bench/ACS/Story/ACS Medicinal Chemistry Letters/2025_1.txt
ave_3
2025_1.txt
X-ray crystal structure of the carboplatin-loaded ferritin nanocage (PDB code 5MIJ). Pt centers coordinate to His49 and His132, on the inner surface of the Ft nanocage. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00025.  View the article.
MAC_Bench/ACS/Story/ACS Medicinal Chemistry Letters/2017_9.txt
vith
2017_9.txt
Mixed aryl acyloxy prodrugs readily cross the cell membrane, release a charged phosphonate ligand that binds to the intracellular domain of BTN3A1, and efficiently stimulate gd T cell proliferation. ACS Med. Chem. Lett. DOI: 10.1021/acsmedchemlett.7b00245. View the article.
MAC_Bench/ACS/Story/ACS Medicinal Chemistry Letters/2017_4.txt
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2017_4.txt
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Industrial & Engineering Chemistry Research
2024_33
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Industrial & Engineering Chemistry Research/2024_33.png
C
2O4 Octahedrons” (DOI: 10.1021/acs.iecr.7b04445); and W. Li et al., “Anisotropic Turbulent Mass Transfer Model and Its Application to a Gas-Particle Bubbling Fluidized Bed” (DOI: 10.1021/acs.iecr.7b03715)
MAC_Bench/ACS/Story/Industrial & Engineering Chemistry Research/2018_47.txt
vitg
2018_47.txt
Lemon juice, a readily available and biodegradable natural substance, was used to prepare carbon dots (CDs) in one step by a microflow approach. The derived CDs
MAC_Bench/ACS/Story/Industrial & Engineering Chemistry Research/2024_42.txt
vith
2024_42.txt
The cover sketches the challenge of integrating multiple scales into a process model and how this can be performed with compartment models. These compartment models are applied to an industrial rotary dryer shown in the figures and the background.
MAC_Bench/ACS/Story/Industrial & Engineering Chemistry Research/2024_33.txt
groundtruth
2024_33.txt
Schematic diagram of photogenerated electron transfer mechanism of tetracycline degradation by
MAC_Bench/ACS/Story/Industrial & Engineering Chemistry Research/2023_23.txt
clip
2023_23.txt
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Macromolecules
2024_13
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Macromolecules/2024_13.png
B
On the cover: Macroscopically aligned helical polyacetylene film was synthesized through acetylene polymerization under monodomain structured chiral nematic liquid crystal reaction field with applied magnetic field of 5 T. See page 5943. View the article.
MAC_Bench/ACS/Story/Macromolecules/2010_11.txt
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2010_11.txt
Schematic representation of a four-dimensional scanning transmission electron microscopy experiment, where the electron beam (in green) scans across a block copolymer sample (in black/white) recording diffraction patterns (below) that reveal the orientation (rainbow colors) of the semicrystalline crystalline structure ...
MAC_Bench/ACS/Story/Macromolecules/2024_13.txt
groundtruth
2024_13.txt
On the cover: The delicate interplay of structure and dynamics in macromolecular and supramolecular systems leads to increasing complexity and functionality. This poses considerable challenges for their physical characterization. No experimental or theoretical/simulation approach alone can provide complete information....
MAC_Bench/ACS/Story/Macromolecules/2010_12.txt
vitg
2010_12.txt
Self-immolative polymers provide an opportunity for controlled deconstruction of macromolecular architectures in response to environmental stimuli. See page 7317. View the article.
MAC_Bench/ACS/Story/Macromolecules/2012_7.txt
ave_2
2012_7.txt
test
Nature Reviews Rheumatology
20_11
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Rheumatology/20_11.png
A
Inspired by the Review on p81. Cover design: Steven Hall
MAC_Bench/Nature/Story/Nature Reviews Rheumatology/20_11.txt
groundtruth
20_11.txt
Inspired by the Review on p257. Cover design: S.Harris/Springer Nature Limited
MAC_Bench/Nature/Story/Nature Reviews Rheumatology/17_8.txt
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Inspired by the Review on p449. Cover design: S.Harris/Springer Nature Limited
MAC_Bench/Nature/Story/Nature Reviews Rheumatology/17_5.txt
vitg
17_5.txt
In our January issue: articles on myofibroblasts in fibrotic diseases, drug repurposing in patients with rheumatic diseases, and behavioural economics in rheumatology. Image of a bone tissue engineering scaffold implanted in a femur defect model. Image supplied by Betül Aldemir Dikici, University of Sheffield. Cover de...
MAC_Bench/Nature/Story/Nature Reviews Rheumatology/16_12.txt
vith
16_12.txt
train
Science
387_6732
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science/387_6732.png
A
COVER A breeding ruff male (Calidris pugnax) in alert posture scans the breeding area for mating opportunities at Liminka Bay, Finland. Ruff males deploy one of three mating tactics that differ in aggressive and courtship behaviors. Differences in aggression between tactics are tied to concentrations of circulating and...
MAC_Bench/Science/Story/Science/387_6732.txt
groundtruth
387_6732.txt
COVER Whiskers at the snout are instrumental for the rat to explore the external world. During development, sensory information provided by the whiskers is critical for the formation of their representation in the brain. Minlebaev et al. show how this process is controlled by gamma oscillations in developing neuronal n...
MAC_Bench/Science/Story/Science/334_6053.txt
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334_6053.txt
COVER Science, like the rest of society, has been swept up in the storms caused by social media. This special news section looks at how scientists study and fight mis- and disinformation, how harassment and intimidation have spiked during the COVID-19 pandemic, and how researchers use Twitter to inform the public and s...
MAC_Bench/Science/Story/Science/375_6587.txt
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COVER In early 2020, governments worldwide introduced lockdowns to curb the spread of COVID-19. These lockdowns severely altered human mobility, with many people confined to their homes. In response, animals such as the coyote (Canis latrans) traveled longer distances and occurred closer to roads. These changes suggest...
MAC_Bench/Science/Story/Science/380_6649.txt
vith
380_6649.txt
train
Med
5_9
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Med/5_9.png
B
On the cover: This issue of Med explores the applications of CAR T cell therapies beyond hematologic malignancies, including solid tumors and autoimmune diseases. A Q&A with Fabian Müller (University Hospital Erlangen) covers the latest developments in the field. A Review from Liu et al. discusses emerging combination ...
MAC_Bench/Cell/Story/Med/5_7.txt
vitg
5_7.txt
On the cover: Camrelizumab, an anti-PD-1 immunotherapy drug, shows promise in treating a range of cancers, including hepatocellular carcinoma, esophageal squamous cell carcinoma, and Hodgkin lymphoma. In a phase 2 clinical trial, Pan et al. demonstrated the safety and feasibility of pre-operative camrelizumab with micr...
MAC_Bench/Cell/Story/Med/5_9.txt
groundtruth
5_9.txt
On the cover: In this issue, Millen et al. (pp. 290–310) describe and characterize a head and neck cancer organoid biobank. Using patient-derived models, they subsequently study the effects of therapies that are combined in the clinic and validate genetic biomarkers for treatment response. They explore whether these mo...
MAC_Bench/Cell/Story/Med/4_8.txt
ave_1
4_8.txt
On the cover: In this issue, Wu et al. investigate the role of dendritic cells (DCs) within the tumor immune microenvironment and their impact on immunotherapy outcomes in patients. Using data from clinical trials and mouse models, they identify a specific functional DC state characterized by CCL19 expression that can ...
MAC_Bench/Cell/Story/Med/4_7.txt
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train
Current Biology
34_2
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Current Biology/34_2.png
A
On the cover: A group of yellow-billed long-tailed finches (Poephila acuticauda) perch on a tree branch. In this issue, Hooper et al. demonstrate the role of selection in the evolution of bill coloration, a carotenoid-based color trait that distinguishes a pair of hybridizing subspecies. Yellow alleles, like the ones c...
MAC_Bench/Cell/Story/Current Biology/34_2.txt
groundtruth
34_2.txt
On the cover: Red factor and yellow canaries. Many species of birds in nature can biochemically modify yellow dietary carotenoids to red ketocarotenoids to produce red coloration of bills and feathers. In this issue, Lopes et al. (pages 1427–1434) and Mundy et al. (pages 1435–1440) independently dissect the genetic bas...
MAC_Bench/Cell/Story/Current Biology/26_14.txt
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26_14.txt
On the cover: In this issue, Drury et al. deploy a new modeling approach and show that the availability of open niches influences the pace of phenotypic evolution across all birds. This image shows a little bee-eater (Merops pusillus), an African invertivore (one of the groups with a particularly strong response to cha...
MAC_Bench/Cell/Story/Current Biology/34_22.txt
vith
34_22.txt
On the cover: With this issue, Current Biologycompletes its twentieth year. Since its origins as a journal publishing “dispatches from the front lines of biology,” Current Biologyhas continuously expanded in terms of both paper formats and breadth of subjects covered. We hope the journal will continue to evolve and loo...
MAC_Bench/Cell/Story/Current Biology/20_1.txt
vitg
20_1.txt
train
Nature Reviews Cardiology
21_6
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Cardiology/21_6.png
D
DEI in Cardiology, inspired by the Roadmap on p765. Cover design: Vicky Summersby.
MAC_Bench/Nature/Story/Nature Reviews Cardiology/19_2.txt
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19_2.txt
Blood pressure variability, inspired by the Review on p643. Cover design: Vicky Summersby.
MAC_Bench/Nature/Story/Nature Reviews Cardiology/19_3.txt
vith
19_3.txt
Cardiovascular involvement in long COVID, inspired by the Review on p314. Cover design: Vicky Summersby.
MAC_Bench/Nature/Story/Nature Reviews Cardiology/19_8.txt
vitg
19_8.txt
Immune checkpoints, inspired by the Review on p443. Cover design: Vicky Summersby
MAC_Bench/Nature/Story/Nature Reviews Cardiology/21_6.txt
groundtruth
21_6.txt
train
Nature Photonics
18_3
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Photonics/18_3.png
B
Scanning near-field optical microscopy reveals the structure of plasmon sheet and edge modes in graphene disk and rectangular nanoresonators. Letter p239 IMAGE: ELLA MARUSHCHENKO COVER DESIGN: BETHANY VUKOMANOVIC
MAC_Bench/Nature/Story/Nature Photonics/10_9.txt
ave_1
10_9.txt
Fluorescence-lifetime image scanning microscopy Integrating a single-photon avalanche detector (SPAD) array into a confocal laser scanning microscope yields a twofold increase in the localization accuracy for single-molecule localization microscopy. The cover shows an artistic impression of the SPAD array detector with...
MAC_Bench/Nature/Story/Nature Photonics/18_3.txt
groundtruth
18_3.txt
The onset of turbulence and coherence loss in fibre laser radiation is studied and found to originate from the clustering of solitons.Letter p783News & Views p767Interview p840IMAGE: ARTEM OVCHARENKO, TURITSYNA ET AL.COVER DESIGN: TOM WILSON
MAC_Bench/Nature/Story/Nature Photonics/7_3.txt
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7_3.txt
The advent of super-resolution imaging schemes that allow optical imaging beyond the diffraction limit of light is revolutionizing sample analysis in the biological and physical sciences. This issue features a special focus on the topic. Cover design by Stefan Hell. Progress article by Stefan W. Hell et al .
MAC_Bench/Nature/Story/Nature Photonics/3_6.txt
vitg
3_6.txt
train
Science Signaling
2007_377
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science Signaling/2007_377.png
D
ONLINE COVERThis week, Caratti et al. report that, in the absence of activating ligands, the glucocorticoid receptor (GR) associates with complexes containing RAS and inhibits RAS activation. The image shows HEK293T cells expressing mCherry-tagged KRAS (red) and EGFP-tagged GR (green). Nuclei are stained blue. Image: C...
MAC_Bench/Science/Story/Science Signaling/15_726.txt
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15_726.txt
ONLINE COVER This week features a Research Article that describes a method for identifying active signaling pathways in cancer tissue samples and shows that this information may enable more effective treatment. The image shows the signal produced by proximity ligation assay for the interaction of EGFR and GRB2 (red), c...
MAC_Bench/Science/Story/Science Signaling/8_359.txt
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8_359.txt
ONLINE COVER This week, Tóth et al. show that when the endocytosis of a G protein–coupled receptor (GPCR) is prevented, even partial agonists of the β-arrestin pathway become full agonists, suggesting that receptor localization plays a role in determining biased GPCR signaling. The image shows the fluorescent signal of...
MAC_Bench/Science/Story/Science Signaling/17_842.txt
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COVER This week features a Perspective on focal adhesions, protein complexes that link the cell interior to the extracellular matrix. The image illustrates a model of focal adhesion proteins functioning as a molecular clutch. [Image: Yu-Li Wang, University of Massachusetts Medical School]
MAC_Bench/Science/Story/Science Signaling/2007_377.txt
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2007_377.txt
train
Science Immunology
10_104
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science Immunology/10_104.png
D
ONLINE COVER Boosting Locally Buffs Up Vaccine-Induced Immunity. This month’s cover shows an immunofluorescence image of a germinal center in a mouse lymph node 5 weeks after a priming immunization with influenza hemagglutinin. Primed B cells fate-mapped for AID expression (green) are present in the central area of a f...
MAC_Bench/Science/Story/Science Immunology/7_71.txt
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7_71.txt
ONLINE COVER Chemical Confinement of Germinal Center B Cells. This month's cover is an immunofluorescence image showing the spleen of a preimmunized mouse injected one day earlier with B cells (in green) expressing the human P2RY8 receptor. Gallman et al. observed that retention of the transferred B cells in germinal c...
MAC_Bench/Science/Story/Science Immunology/6_60.txt
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ONLINE COVER Teaming Up to Defend. Depicted here are CD141+ dendritic cells (DCs, green), which resist infection by enveloped viruses (yellow spheres), and CD1c+ DCs (orange), which are susceptible to infection. Silvin et al. report that CD141+ DCs acquire viral antigen from infected CD1c+ DCs and prime antiviral T cel...
MAC_Bench/Science/Story/Science Immunology/2_13.txt
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ONLINE COVER Immune Hotspots in Multiple Myeloma. Multiple myeloma (MM) is a plasma cell malignancy that develops in the bone marrow but can expand as breakout lesions into neighboring soft tissues as the disease progresses. Using single-cell and spatial multiomics, Lutz et al. compared the cellular composition of bone...
MAC_Bench/Science/Story/Science Immunology/10_104.txt
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10_104.txt
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Current Biology
34_5
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Current Biology/34_5.png
C
On the cover: The early evolution of Cyanobacteria and oxygenic photosynthesis has been difficult to retrace, partly because very few extant representatives are available from Gloeobacteria, an isolated lineage that is sister to the rest of Cyanobacteria. In this issue, Rahmatpour et al. (pages 2857–2867) isolate and d...
MAC_Bench/Cell/Story/Current Biology/31_12.txt
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31_12.txt
On the cover: Old oak branches laden with epiphytes in the coastal region of South Carolina, USA. As primary producers, plants are the backbone of nearly all of Earth’s ecosystems, forming a complex web of interactions with microbes, fungi, and animals—as well as other plants. Because of their limited mobility, plants ...
MAC_Bench/Cell/Story/Current Biology/33_14.txt
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On the cover: Common pond skaters (Gerris lacustris) on the surface of a river in the Lake District, UK. These predatory insects exploit the high surface tension of water to skate across the water's surface, a process facilitated by their long, hydrophobic legs and the distribution of their weight over a large surface ...
MAC_Bench/Cell/Story/Current Biology/34_5.txt
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34_5.txt
On the cover: With this issue, Current Biologycompletes its twentieth year. Since its origins as a journal publishing “dispatches from the front lines of biology,” Current Biologyhas continuously expanded in terms of both paper formats and breadth of subjects covered. We hope the journal will continue to evolve and loo...
MAC_Bench/Cell/Story/Current Biology/20_1.txt
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20_1.txt
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Science Translational Medicine
17_786
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science Translational Medicine/17_786.png
D
ONLINE COVER Transforming Lung Cancer. The cover illustrates a lung adenocarcinoma cell (pink) transitioning to an intermediate state (purple) that can then transdifferentiate into a lung squamous cell carcinoma cell (red) or small cell lung carcinoma cell (blue). This issue of Science Translational Medicine features a...
MAC_Bench/Science/Story/Science Translational Medicine/16_760.txt
ave_0
16_760.txt
ONLINE COVER Covering 10 Years of Translation. The image shows a collection of Science Translational Medicine covers, one for each year of the journal's publication. To celebrate Science Translational Medicine's 10th anniversary and a decade of exciting translational research, we are launching with this issue a special...
MAC_Bench/Science/Story/Science Translational Medicine/11_477.txt
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11_477.txt
ONLINE COVER An Adjuvant Advance. The cover shows a mouse inguinal lymph node after vaccination with the BNT162b2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine adjuvanted with a lipid nanoparticle-encapsulated mRNA encoding interleukin (IL)–12p70. The lymph node was stained for naïve (yellow...
MAC_Bench/Science/Story/Science Translational Medicine/16_757.txt
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ONLINE COVER Identity Crisis. The cover shows YFP (green), insulin (red, overlap with YFP in yellow), and a DNA counterstain (blue) in the pancreas of a 3-week-old mouse model of Wolfram syndrome (WS) lacking the Wfs1 gene. WS is an inherited disorder that results in multiple systemic symptoms including pancreatic β ce...
MAC_Bench/Science/Story/Science Translational Medicine/17_786.txt
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Crystal Growth & Design
2024_4
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Crystal Growth & Design/2024_4.png
C
An Fmoc-CF hydrogel incorporated inside a lysozyme crystal is able to protect the enzyme molecules from the radicals generated by X-rays during data collection avoiding local radiation damage (Cryst. Growth Des. 2019, 19, 4229–4233).
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The cover shows two conformers of resorcinol and a single crystal of resorcinol polymorphs α grown in a high-pressure diamond-anvil cell. Resorcinol polymorphs were determined in the 1930s, but their metastable phases, symmetry, and densities have remained puzzling. The high-pressure structures reveal the mechanism des...
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supramolecular polymeric motifs are combined in one crystal to produce the platforms for multimodal thermally tuned blue-to-green and/or NIR photoluminescence. The background of the cover image was generated by artificial intelligence (AI) using Microsoft Copilot.
MAC_Bench/ACS/Story/Crystal Growth & Design/2024_4.txt
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With the exploration of tyramine's role as a prolific coformer, this study delves into its extensive co-crystallization capabilities with diverse acids, analyzing crystal structures and electron density to uncover the key factors driving its versatility in multicomponent crystal formation.
MAC_Bench/ACS/Story/Crystal Growth & Design/2025_4.txt
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Chemical & Biomedical ImagingOpen Access
2024_10
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Chemical & Biomedical ImagingOpen Access/2024_10.png
B
molecular fingerprint
MAC_Bench/ACS/Story/Chemical & Biomedical ImagingOpen Access/2024_3.txt
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A label-free 3D tomogram of COVID-19 microclots was recorded using a digital holotomographic microscope.
MAC_Bench/ACS/Story/Chemical & Biomedical ImagingOpen Access/2024_10.txt
groundtruth
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A universal, rapid and large-scale synthesis strategy for chiral fluorescent
MAC_Bench/ACS/Story/Chemical & Biomedical ImagingOpen Access/2024_1.txt
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The cover design is inspired by the fluorogenic reaction and click reaction. As depicted in the image, nonluminous planets interact with each other to generate new small planets that emit intense fluorescent light, enabling diverse research applications. View the article.
MAC_Bench/ACS/Story/Chemical & Biomedical ImagingOpen Access/2023_3.txt
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Nature Neuroscience
27_1
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Neuroscience/27_1.png
A
Focus on single-cell genomics in neuroscience Single-cell and single-nucleus genomics pave the way for a comprehensive understanding of the nervous system and its diverse cell populations. Realizing this potential depends on meticulous planning, execution, and analysis. In this Focus Issue, three reviews from leaders i...
MAC_Bench/Nature/Story/Nature Neuroscience/27_1.txt
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Focus on neuroscience methods In this focus issue on neuroscience methods we present a series of reviews, perspectives and commentaries that highlight advances in methods and analytical approaches and provide guidelines and best practices in various areas of neuroscience. Image: Jennie Vallis. Cover design: Marina Corr...
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23_1.txt
This month's special issue of Nature Neuroscience features a series of reviews and opinionated pieces on the theme of spatial cognition.
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20_2.txt
Shu and colleagues show that two sodium channel subtypes, a high-threshold Nav1.2 and a low-threshold Nav1.6, are asymmetrically distributed in the axon initial segment (AIS). This asymmetrical distribution explains many of the unique properties of the AIS, including its generation of backpropagating action potentials....
MAC_Bench/Nature/Story/Nature Neuroscience/12_5.txt
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Nature Reviews Neurology
20_5
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_5.png
C
Single-cell technologies and brain disease, inspired by the Review on p346. Cover design: Philip Patenall
MAC_Bench/Nature/Story/Nature Reviews Neurology/19_7.txt
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Microglia in the tumour microenvironment, inspired by the Review on p243. Cover design: Philip Patenall.
MAC_Bench/Nature/Story/Nature Reviews Neurology/17_9.txt
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17_9.txt
Neurology in the midnight sun, inspired by the Q&A on p453. Cover design: Amie Fernandez
MAC_Bench/Nature/Story/Nature Reviews Neurology/20_5.txt
groundtruth
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Synaptic degeneration in Alzheimer disease, inspired by the Review on p19. Cover design: Philip Patenall
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NATURE REVIEWS NEUROSCIENCE
25_10
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE REVIEWS NEUROSCIENCE/25_10.png
C
'Building a big brain project' by Jennie Vallis, inspired by the Viewpoint on p659.
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‘Neuroconnectionism’, inspired by the Perspective on p431 Cover design: Jennie Vallis
MAC_Bench/Nature/Story/NATURE REVIEWS NEUROSCIENCE/24_6.txt
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‘Light and cognition’, inspired by the Review on p159. Cover design: Jennie Vallis
MAC_Bench/Nature/Story/NATURE REVIEWS NEUROSCIENCE/25_10.txt
groundtruth
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‘Brain activity on the move’, inspired by the Perspective on p347. Cover design: Jennie Vallis
MAC_Bench/Nature/Story/NATURE REVIEWS NEUROSCIENCE/24_7.txt
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24_7.txt
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Journal of Chemical Theory and Computation
2024_22
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Journal of Chemical Theory and Computation/2024_22.png
B
The
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2020_4.txt
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2020_4.txt
Solvent effects on the conformational dynamics and response to light excitation of multinuclear mixed valence metal complexes can be unveiled by mixed quantum classical approaches, based on molecular dynamics simulations carried out with quantum mechanically derived force-fields.
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2024_22.txt
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for clinical decision support. J. Chem. Theory Comput. 2017, 13,  210–222.
MAC_Bench/ACS/Story/Journal of Chemical Theory and Computation/2017_9.txt
vith
2017_9.txt
A machine learning approach LINES is used to accelerate sampling of binding sites around TIM3 and P26. The strongest binding site is targeted and found to support stable binding in a pose that we hypothesize blocks TIM3-GAL9 binding, a reaction that is known to suppress immune responses.
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Nature Reviews Earth & Environment
5_1
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Earth & Environment/5_1.png
B
The planetary boundaries framework outlines a safe operating space for humanity according to key Earth System dynamics. This Perspective proposes the addition of a green water planetary boundary based on root-zone soil moisture, and demonstrates that widespread green water modifications now present increasing risks to ...
MAC_Bench/Nature/Story/Nature Reviews Earth & Environment/3_7.txt
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Land-use and climate changes can reduce the resilience of river deltas to regime shifts in channel morphodynamics, estuarine turbidity and the state of coastal wetlands. This Review discusses how these regime shifts can be triggered, monitored and prevented. Universal Images Group North America LLC / Alamy Stock Photo....
MAC_Bench/Nature/Story/Nature Reviews Earth & Environment/5_1.txt
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Mangroves, tidal marshes and seagrass meadows have historically been lost or degraded, threatening their ability to store carbon and provide ecosystem services. This Review details the global potential of blue carbon ecosystem protection and restoration in climate change mitigation, through carbon sequestration and co-...
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Non-perennial segments of rivers undergo cycles of flowing, non-flowing and dry phases, influencing ecosystem dynamics and services across the river network. This Review describes the occurrence, ecology and future of these intermittent and ephemeral flows and highlights the importance of protecting these segments. Ima...
MAC_Bench/Nature/Story/Nature Reviews Earth & Environment/4_1.txt
vith
4_1.txt
train
Med
5_6
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Med/5_6.png
B
On the cover: This issue of Med explores the applications of CAR T cell therapies beyond hematologic malignancies, including solid tumors and autoimmune diseases. A Q&A with Fabian Müller (University Hospital Erlangen) covers the latest developments in the field. A Review from Liu et al. discusses emerging combination ...
MAC_Bench/Cell/Story/Med/5_7.txt
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5_7.txt
On the cover: Chemotherapies are currently dosed based on a patient's height and weight, using an equation from 1916 to estimate their body surface area. This method leads to variability in pharmacokinetics, potentially causing increased toxicities and decreased efficacy. Personalized dosing could improve the patient's...
MAC_Bench/Cell/Story/Med/5_6.txt
groundtruth
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On the Cover: The events of 2020 have highlighted the existing health disparities among people of different races and ethnicities throughout the world and the urgent need for equitable access to healthcare solutions. The January 2021 issue of Med explores the complex relationships between diversity, race and health. Co...
MAC_Bench/Cell/Story/Med/2_12.txt
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2_12.txt
On the Cover: While monoclonal antibodies against SARS-CoV-2 have received emergency approval for treatment, they do not persist in serum for extended periods and must be administered intravenously, which affects their use. In this issue, Cobb et al. (pp. 188–203) report the development of ADM03820, a neutralizing anti...
MAC_Bench/Cell/Story/Med/3_10.txt
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Acta Pharmacologica Sinica
45_3
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_3.png
A
Cover Credit: CircNSD1 acts as ceRNA of miR-429-3p to promote the target gene SULF1 expression and activate Wnt/β-catenin pathway signaling to enhance fibroblasts proliferation and collagen deposition leading to cardiac fibrosis. (DOI 10.1038/s41401-024-01296-7). See the article in pages 2092-2106.
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_3.txt
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Cover Credit: DZ2002, a reversible inhibitor of type III S-adenosyl-L-homocysteine hydrolase, attenuates TNF-α-induced NF-κB signaling by suppressing the degradation and phosphorylation of IκB, along with NF-κB p65 phosphorylation and nuclear translocation. Additionally, DZ2002 inhibits the activation of molecules in t...
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_12.txt
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Cover Credit: Mechanisms of Takeda G protein-coupled receptor-5 (TGR5) agonist on inhibiting intestinal epithelial cell apoptosis and ameliorating ulcerative colitis. Activation of TGR5 by OM8 enhanced cAMP/PKA signaling, which led to upregulation of c-FLIP expression, and subsequently suppressed JNK phosphorylation, t...
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/44_5.txt
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44_5.txt
Cover Credit: Urolithin A, as a fruit-derived natural product, protects against atherosclerotic plaque vulnerability by pleiotropic mechanisms, including promoting NO production, inhibiting YAP/TAZ-dependent endothelial inflammation as well as lowering lipid levels. Doi:10.1038/s41401-024-01317-5. See the article in pa...
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_2.txt
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NATURE ENERGY
9_9
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE ENERGY/9_9.png
D
Now we are five Nature Energy launched its first issue five years ago. To mark the occasion, this month we take a look back at some of our past content and catch up with some of our early authors. See Editorial Image: Anton Eine/Alamy Stock Photo. Cover Design: Thomas Phillips.
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The power to respond Energy is used in the delivery of many functions of humanitarian aid, from shelter, lighting and transport, to clean water, sanitation, and medical assistance. This Focus issue explores how thinking around energy is changing as the need for sustainable energy solutions in refugee camps intensifies ...
MAC_Bench/Nature/Story/NATURE ENERGY/4_1.txt
vitg
4_1.txt
Fuel for the future Our energy systems are undergoing large-scale changes as we try to overcome many societal and environmental challenges. Doing this successfully requires the efforts of many different researchers across a range of technologies and systems, each of which faces their own issues and concerns for the fut...
MAC_Bench/Nature/Story/NATURE ENERGY/1_12.txt
ave_3
1_12.txt
Clean cooking transition experiences Adapting to cleaner cooking fuels from more polluting options may be experienced differently by different groups across various stages of the energy transition. Kar et al. analyse survey data on household-level energy use in Ghana as the country shifts towards cleaner cooking fuels....
MAC_Bench/Nature/Story/NATURE ENERGY/9_9.txt
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9_9.txt
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Trends in Cancer
10_10
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Cancer/10_10.png
D
We invite readers to explore the newest addition to the Trends collection Trends in Cancer, which aims to cover a range of topics in cancer research including the latest developments in basic, translational and clinical sciences, pharma R&D, technology, ethics, and policy. The inaugural issue of Trends in Cancer tackle...
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Variations in cancer incidence fuel the debate on the relative contributions of intrinsic vs extrinsic factors. On pages 409–415 in this issue, Thomas et al. add an extra piece to the puzzle by exploring the concept of evolutionary ecology in oncogenesis, and discuss how an organ ecosystem and its contribution to Darwi...
MAC_Bench/Cell/Story/Trends in Cancer/2_5.txt
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2_5.txt
Aging is a strong predictor of cancer, which is often viewed as a senescence-related disease. On pages 169–172 in this issue, Thomas et al. reflect on cancer from an evolutionary biology perspective, and argue for reassessing the “senescence view” considering that cancer is a strong selective force early on in the life...
MAC_Bench/Cell/Story/Trends in Cancer/4_11.txt
vith
4_11.txt
Many therapeutic strategies that are positive in preclinical mice experiments fail in human clinical trials due to biological differences between mice and humans. In this issue, Joshi et al. propose using pigs as alternative animals for preclinical testing due to their many similarities shared with humans. In particula...
MAC_Bench/Cell/Story/Trends in Cancer/10_10.txt
groundtruth
10_10.txt
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Macromolecules
2024_4
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Macromolecules/2024_4.png
C
Self-immolative polymers provide an opportunity for controlled deconstruction of macromolecular architectures in response to environmental stimuli. See page 7317. View the article.
MAC_Bench/ACS/Story/Macromolecules/2012_7.txt
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Polyelectrolyte complexation is associative phase separation of oppositely charged polyelectrolytes in aqueous media. See Macromolecules, 2018, 51 (8), pp 2988–2995. View the article.
MAC_Bench/ACS/Story/Macromolecules/2018_16.txt
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2018_16.txt
L-Glutamic acid acts as molecular glue connecting αlanine units to produce fluorescent poly-Glu-Ala. View the article.
MAC_Bench/ACS/Story/Macromolecules/2024_4.txt
groundtruth
2024_4.txt
On the cover: Macroscopically aligned helical polyacetylene film was synthesized through acetylene polymerization under monodomain structured chiral nematic liquid crystal reaction field with applied magnetic field of 5 T. See page 5943. View the article.
MAC_Bench/ACS/Story/Macromolecules/2010_11.txt
vith
2010_11.txt
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Trends in Microbiology
33_2
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Microbiology/33_2.png
D
This themed issue of Trends in Microbiology explores different aspects of microbial endurance and how microbes endure and flourish in the environments they find themselves in. We examine how bacteria and viruses establish chronic infections – from adaptation and population diversity, to the latent reservoir in HIV as w...
MAC_Bench/Cell/Story/Trends in Microbiology/24_9.txt
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This themed issue of Trends in Microbiology examines the role that metabolism plays in microbial life ranging from how microbes obtain energy to how microbes can alter the metabolism of their host and use host-derived metabolites to their advantage. The cover image was inspired by the hypothesis that perhaps pathogenic...
MAC_Bench/Cell/Story/Trends in Microbiology/19_6.txt
vitg
19_6.txt
In this issue on broad concepts in microbiology we celebrate the 25th anniversary of Trends in Microbiology and explore the concepts that have grown through the history of the journal and the emerging areas within these topics. On pages 376–385, Ariel Amir and Nathalie Balaban review recently invoked methods which rely...
MAC_Bench/Cell/Story/Trends in Microbiology/26_9.txt
vith
26_9.txt
In this issue, Gerber-Tichet et al. provide an update on the expanding role of the function of Toll-like receptor 4 (TLR4), a germline-encoded pattern recognition receptor (PRR). The archetypal role TLR4 is the detection bacterial wall components, including lipopoly- and lipo-oligo-saccharides (LPS and LOS). The cover ...
MAC_Bench/Cell/Story/Trends in Microbiology/33_2.txt
groundtruth
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train
ACS Physical Chemistry Au
2024_6
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS Physical Chemistry Au/2024_6.png
D
The cover features the kinetics of tetracyanoethylene on a copper surface at two different temperatures. For increasing dosages, the system undergoes a thermodynamically driven phase transition from lying to standing. As this transition notably changes the physical properties of the interface, we study how to kinetical...
MAC_Bench/ACS/Story/ACS Physical Chemistry Au/2022_6.txt
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This front cover depicts the artwork created by Tianruo Shen, the first chemist from a family of medical professionals. This cover and accompanying Editorial are part of the
MAC_Bench/ACS/Story/ACS Physical Chemistry Au/2023_1.txt
vith
2023_1.txt
The cover features the interaction at the nanoscale between amine functionalized polymers and sodium ions competing for mica binding sites. By varying the concentration of the species in play, for the first time, we systematically observe a trend in the macroscopic adhesion measurements, which can be predicted well by ...
MAC_Bench/ACS/Story/ACS Physical Chemistry Au/2021_1.txt
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Amino acids will be observed remotely, the diffuse interstellar bands will be linked to molecular carriers, and direct spectral observations of exoplanetary atmospheres will produce clear chemical signals.
MAC_Bench/ACS/Story/ACS Physical Chemistry Au/2024_6.txt
groundtruth
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val
Nano Letters
2025_8
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Nano Letters/2025_8.png
B
The cover art shows a STM image of bilayer FeSb films epitaxially grown on a SrTiO3(001) substrate with a well-ordered Kagome lattice clearly revealed (inset). View the article.
MAC_Bench/ACS/Story/Nano Letters/2024_51.txt
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2024_51.txt
The cover art depicts a microtubule structure with intact and open segments exposing the inner surface. Atomic force microscopy reveals a high-resolution view, showing an undulating arrangement of protofilaments (PFs) with alternating height variations, caused by different structural orientations and conformations of α...
MAC_Bench/ACS/Story/Nano Letters/2025_8.txt
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This cover shows a three-dimensionally rendered ultra-high vacuum scanning tunneling microscope image of 10,12-pentacosadiynoic acid (PCDA) molecular chains on an epitaxial graphene surface. PCDA is used as a template for growing sub-10 nm oxide nanostructures on graphene via atomic layer deposition. Justice M. P. Alab...
MAC_Bench/ACS/Story/Nano Letters/2013_1.txt
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This cover shows the friction between a pair of silicon anvils in the non-Amontons (high pressure) and non-Coulomb (low sliding speed) regime. The nanometer-scale silicon crystalline anvils are brought into contact and form a decrystalized junction due to high pressure. The lower anvil moves laterally at low sliding...
MAC_Bench/ACS/Story/Nano Letters/2015_10.txt
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2015_10.txt
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Immunity
57_3
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Immunity/57_3.png
D
On the cover: 2019 marks the 25th anniversary of Immunity. The cover for this anniversary issue was designed to celebrate our authors, reviewers, and readers and was created with photos submitted by immunology labs from around the world (download the high-resolution image here). These photos, along with information abo...
MAC_Bench/Cell/Story/Immunity/50_3.txt
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On the cover: The generation of affinity matured antibodies to T cell-dependent (TD) antigens occurs in dynamic structures called germinal centers (GCs). TD antibody formation in GCs requires both a specialized set of T cells referred to as T follicular helper (Tfh) cells in addition to cognate B cells. In this issue o...
MAC_Bench/Cell/Story/Immunity/34_1.txt
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On the cover: 2024 marks the 30th anniversary of Immunity! To celebrate this milestone with the immunology community, we hosted an open call for cover submissions for our special anniversary issue and are grateful to have received beautiful and creative submissions from across the globe! The winning design featured on ...
MAC_Bench/Cell/Story/Immunity/57_9.txt
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On the cover: The thymus involutes as we age, leading to reduced numbers of recent thymic emigrant (RTE) naive T cells in circulation. Bohacova, Terekhova et al. examine human RTEs in a cohort of 158 individuals, providing insight into the impact of age on RTE profile and functional potential and defining CD38 expressi...
MAC_Bench/Cell/Story/Immunity/57_3.txt
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Science Translational Medicine
17_785
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science Translational Medicine/17_785.png
A
ONLINE COVER Expanding Liver Gene Editing. The cover shows gene-targeted and expanded adult mouse hepatocytes (red) and a counterstain for DNA (blue). Homology-directed repair (HDR)-based techniques show promise for gene editing of liver diseases, but they do not always achieve sufficient editing of adult cells. To imp...
MAC_Bench/Science/Story/Science Translational Medicine/17_785.txt
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ONLINE COVER Transforming Lung Cancer. The cover illustrates a lung adenocarcinoma cell (pink) transitioning to an intermediate state (purple) that can then transdifferentiate into a lung squamous cell carcinoma cell (red) or small cell lung carcinoma cell (blue). This issue of Science Translational Medicine features a...
MAC_Bench/Science/Story/Science Translational Medicine/16_760.txt
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ONLINE COVER An Adjuvant Advance. The cover shows a mouse inguinal lymph node after vaccination with the BNT162b2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine adjuvanted with a lipid nanoparticle-encapsulated mRNA encoding interleukin (IL)–12p70. The lymph node was stained for naïve (yellow...
MAC_Bench/Science/Story/Science Translational Medicine/16_757.txt
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ONLINE COVER Covering 10 Years of Translation. The image shows a collection of Science Translational Medicine covers, one for each year of the journal's publication. To celebrate Science Translational Medicine's 10th anniversary and a decade of exciting translational research, we are launching with this issue a special...
MAC_Bench/Science/Story/Science Translational Medicine/11_477.txt
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11_477.txt
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Trends in Genetics
40_7
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Genetics/40_7.png
C
This Special Issue of Trends in Genetics covers a range of themes related to organogenesis, from the formation of the central nervous system to the evolution of the insect eye. The articles in this issue highlight the commonalities of organ formation that are shared across species and kingdoms, and provide insight on t...
MAC_Bench/Cell/Story/Trends in Genetics/31_7.txt
vith
31_7.txt
The neuronal methylome is distinct from other cell types. While the classical form of methylation at CG residues is present across all cell types, neurons are uniquely enriched for methylation outside of this context at CA, CT, and CC (CH) residues. The illustration on the cover highlights the differences in patterns o...
MAC_Bench/Cell/Story/Trends in Genetics/36_2.txt
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The neuronal composition that makes up our brains is relatively stable from shortly after birth to adulthood. However, these post-mitotic neurons continue to undergo property changes throughout the lifespan. In this issue, Gabrielle Prince, Molly Reynolds, Verdion Martina, and HaoSheng Sun describe recent characterizat...
MAC_Bench/Cell/Story/Trends in Genetics/40_7.txt
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In this special issue of Trends in Genetics, we turn the lens on ourselves. The articles this month focus on human genetics, with topics ranging from resources and methods to make the most of the explosion of sequencing data to evolutionary questions about mutation rates and how selection acts through pregnancy.
MAC_Bench/Cell/Story/Trends in Genetics/29_4.txt
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Nature Reviews Materials
10_1
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Materials/10_1.png
A
Tissue biomechanics provides essential biological information that is important for various biomedical applications, and conformable electronic devices are instrumental for decoding this information. The cover shows an artist’s impression of island-bridge structures, consisting of rigid functional "islands" connected b...
MAC_Bench/Nature/Story/Nature Reviews Materials/10_1.txt
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Metamaterials provide a platform to leverage optical signals for performing specific-purpose computational tasks with ultra-fast speeds. This Review surveys the basic principles, recent advances and promising future directions for wave-based-metamaterial analogue computing systems. See Zangeneh-Nejad et al. Image: Roma...
MAC_Bench/Nature/Story/Nature Reviews Materials/6_10.txt
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6_10.txt
Chalcogenide phase-change materials (PCMs) are leading candidates for non-volatile memory and neuro-inspired computing devices. This Review focuses on the crystallization mechanisms of PCMs as well as the design principles to achieve PCMs with high switching speeds and good data retention. See Zhang et al. Image: Ider ...
MAC_Bench/Nature/Story/Nature Reviews Materials/4_10.txt
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The field of molecular magnetism has expanded from the chemical design and study of single-molecule magnets and magnetic materials, to more physics- and nanotechnology-driven areas. In this Review, this change in focus is discussed and molecular magnetism in combination with either molecular spintronics, quantum techno...
MAC_Bench/Nature/Story/Nature Reviews Materials/5_11.txt
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ACS Applied Bio Materials
2024_12
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS Applied Bio Materials/2024_12.png
A
The antibacterial properties of nanosheet-shaped crystalline assemblies of enzymatically synthesized aminated cellulose oligomers (namely, surface-aminated synthetic nanocelluloses) and their synergy with a metal-chelating antibacterial agent, ethylenediaminetetraacetic acid, were demonstrated.
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2024_12.txt
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The cover image depicts a supramolecular switching surface that can be easily switched between bactericidal and antifouling states by host−guest interaction. As the negatively charged macrocyclic host S6-corona[3]arene[3]pyridazine (S6-CAP) are incorporated to the bactericidal surface, the bactericidal ability of the s...
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2019_11.txt
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The cover image depicts the semiconducting oligomer amphiphiles (OPV-PEG)-based activatable nanoprobes for in vivo imaging of biothiols. OPV-PEG is composed of a hydrophobic semiconducting segment that serves as both the signal source and the sensing moiety for biothiols, and the hydrophilic poly(ethylene glycol) (PEG)...
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2018_3.txt
The cover image portrays an injectable neutrophilic attractant and antibacterial hydrogel applied to infected wounds. This hydrogel is made of κ-Carrageenan incorporated with octenidine dihydrochloride and chitosan-treated serum. Octenidine, an antiseptic agent, shows antibacterial activity by rupturing the bacterial m...
MAC_Bench/ACS/Story/ACS Applied Bio Materials/2019_12.txt
vitg
2019_12.txt
train
Nature Reviews Physics
6_5
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Physics/6_5.png
A
The cover of this issue is based on ab initio predictions of superconducting critical temperatures. See Pellegrini & Sanna Image: Adapted from Pellegrini, C. & Sanna, A. Nat. Rev. Phys. (2024) Cover design: Susanne Harris.
MAC_Bench/Nature/Story/Nature Reviews Physics/6_5.txt
groundtruth
6_5.txt
The cover of this issue is inspired by a Review on quantum programming languages. See Bettina Heim et al. Cover design: Charlotte Gurr.
MAC_Bench/Nature/Story/Nature Reviews Physics/2_1.txt
vith
2_1.txt
The cover shows a tiled microscopy image of a monolayer MoS2 sample, contacted with metal contacts. See Wang & Chhowalla Image: Yan Wang, University of Cambridge. Cover design: Charlotte Gurr.
MAC_Bench/Nature/Story/Nature Reviews Physics/4_11.txt
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4_11.txt
The cover of this issue shows a photograph of a spontaneous parametric down-conversion Type I beam and is inspired by a Review on imaging with quantum states of light. See Moreau et al. Image: Paul-Antoine Moreau, University of Glasgow. Cover Design: Carl Conway
MAC_Bench/Nature/Story/Nature Reviews Physics/1_7.txt
vitg
1_7.txt
train
NATURE MATERIALS
24_1
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE MATERIALS/24_1.png
D
Electronically morphing microrobot A kirigami metasheet microrobot shows electronically programmable shape morphing and movement. See Liu et al. Image: Zihe Liang and Qingkun Liu, Shanghai Jiao Tong University; Itai Cohen, Cornell University. Cover design: Alex Whitworth
MAC_Bench/Nature/Story/NATURE MATERIALS/24_2.txt
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24_2.txt
Nanoscale environments created by topological defects in liquid crystals can serve as a template for the self-assembly of molecular amphiphiles within the defects. Article p106; News & Views p10 IMAGE: NICHOLAS ABBOTT GROUP COVER DESIGN: DAVID SHAND
MAC_Bench/Nature/Story/NATURE MATERIALS/15_12.txt
ave_2
15_12.txt
Complex element coupling expands materials capabilities Increasing compositional complexity expands the space of manipulating materials properties, bringing both opportunities and challenges to design and processing. See Xue et al. & Editorial Image: background, Yuichiro Chino / Moment / Getty; structure, Hang Xue & Ch...
MAC_Bench/Nature/Story/NATURE MATERIALS/22_9.txt
vith
22_9.txt
Electronically morphing microrobot A kirigami metasheet microrobot shows electronically programmable shape morphing and movement. See Liu et al. Image: Zihe Liang and Qingkun Liu, Shanghai Jiao Tong University; Itai Cohen, Cornell University. Cover design: Alex Whitworth
MAC_Bench/Nature/Story/NATURE MATERIALS/24_1.txt
groundtruth
24_1.txt
train
Trends in Biotechnology
42_5
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Biotechnology/42_5.png
D
On pages 448–458, Zahra Hamrang and colleagues review emerging trends and novel technologies that offer a promising potential for accurately predicting and profiling protein aggregation at various stages of biopharmaceutical product design. The cover image is from iStockPhoto and design is by Paige Shaklee.
MAC_Bench/Cell/Story/Trends in Biotechnology/31_5.txt
vitg
31_5.txt
Trends in Biotechnology is celebrating its 30th year of publishing exciting reviews in biotechnology. The coverimage shows microbes taking advantage of the occasion. Cover image made by Julien Husson and coverdesigned by Paige Shaklee.
MAC_Bench/Cell/Story/Trends in Biotechnology/31_11.txt
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31_11.txt
CRISPR/Cas and other genome editing approaches have quickly become centrally important biotechnological techniques in synthetic biology. This month, we focus on emerging aspects of genome editing ranging from generating high-value chemicals in prokaryotes to designing synthetic gene circuits. In pages 535–547 of this i...
MAC_Bench/Cell/Story/Trends in Biotechnology/34_7.txt
vith
34_7.txt
Systems and synthetic biology control 'knobs' can design and reprogram bacterial phenotypes, illustrated as light bulbs. However, inherent genomic redundancies and the presence of unknown factors make genome manipulation difficult and undermine the performance of desired functionalities. In pages 1048–1063 of this issu...
MAC_Bench/Cell/Story/Trends in Biotechnology/42_5.txt
groundtruth
42_5.txt
val
ACS Chemical Neuroscience
2024_22
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_22.png
C
.
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2010_12.txt
vitg
2010_12.txt
10.1021/acschemneuro.0c00004
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2020_21.txt
clip
2020_21.txt
Unraveling the interplay between dopamine, carbon monoxide, and heme oxygenase: suggesting an axis that likely plays important roles in neuromodulation and cognition.
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2024_22.txt
groundtruth
2024_22.txt
The mechanisms accounting for the formation of pores by amyloid peptides are revealed by unbiased all-atom simulations. Peptides adsorb, aggregate into β-sheets, and form pores spontaneously at the surface of lipid bilayers. Four peptides differing in the distribution of polar and nonpolar residues along the sequence a...
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2024_7.txt
vith
2024_7.txt
test
Nature Reviews Physics
6_3
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Physics/6_3.png
C
The cover of this issue illustrates the physics and sustainability theme launching this month. See Editorial Cover design: Susanne Harris.
MAC_Bench/Nature/Story/Nature Reviews Physics/5_10.txt
vitg
5_10.txt
The cover of this issue shows the Large Hadron Collider at CERN. In a Focus on future particle accelerators we explore the proposed projects and underlying technologies that would make the next big particle collider possible. See Editorial Image: The Large Hadron Collider, CERN.
MAC_Bench/Nature/Story/Nature Reviews Physics/1_9.txt
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1_9.txt
The cover of this issue is based on the CERN accelerator complex. See the Editorial. Image: S.Harris/Springer Nature Limited.
MAC_Bench/Nature/Story/Nature Reviews Physics/6_3.txt
groundtruth
6_3.txt
The cover of this issue shows a network of similar products for the Egyptian economy. See César Hidalgo Image: César Hidalgo, ANITI, University of Toulouse, France. Cover design: Charlotte Gurr.
MAC_Bench/Nature/Story/Nature Reviews Physics/3_11.txt
vith
3_11.txt
train
Journal of the American Chemical Society
2024_34
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_34.png
D
Through massive molecular dynamics simulations, it was found that the fluorine domain endows fluorinated ionic liquids ultrahigh solubility of nitrogen. Meanwhile, a theoretical model of fluorine densification energy was also constructed to predict the abnormal solubility of nitrogen based on the microscopic structure ...
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_15.txt
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2024_15.txt
The surprising solvation environment of methylglyoxal at the air/liquid water interface suggests new chemical pathways for hydration that are more feasible in the absence of atmospheric acid catalyzers.
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2020_39.txt
vith
2020_39.txt
A flow platform has been developed for the rapid assembly of polypeptides through native chemical ligation coupled with a novel photodesulfurization transformation. This technology was used to prepare the clinically approved HIV therapeutic enfuvirtide and the diagnostic agent somatorelin 2 orders of magnitude faster t...
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2018_23.txt
vitg
2018_23.txt
Tuning acid/base electrochemistry via hydrophobicity and electric fields.  View the article.
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_34.txt
groundtruth
2024_34.txt
train
Nature Reviews Neurology
20_10
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Neurology/20_10.png
B
Microglia in the tumour microenvironment, inspired by the Review on p243. Cover design: Philip Patenall.
MAC_Bench/Nature/Story/Nature Reviews Neurology/17_9.txt
vitg
17_9.txt
Seizures in Alzheimer disease, inspired by the Review on p162. Cover design: Philip Patenall
MAC_Bench/Nature/Story/Nature Reviews Neurology/20_10.txt
groundtruth
20_10.txt
Modelling Alzheimer disease in a dish, inspired by the Review on p25. Cover design: Philip Patenall.
MAC_Bench/Nature/Story/Nature Reviews Neurology/18_12.txt
clip
18_12.txt
Synaptic degeneration in Alzheimer disease, inspired by the Review on p19. Cover design: Philip Patenall
MAC_Bench/Nature/Story/Nature Reviews Neurology/19_12.txt
ave_0
19_12.txt
test
Molecular Pharmaceutics
2024_10
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Molecular Pharmaceutics/2024_10.png
B
Berberine chloride and four aliphatic dicarboxylic acids form novel cocrystals with higher melting point, improved dissolution, and lower hygroscopicity. The melting points and intrinsic dissolution rates of these cocrystals exhibit an
MAC_Bench/ACS/Story/Molecular Pharmaceutics/2021_9.txt
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2021_9.txt
This image represents a painting of a monolayer of lymphatic endothelial cells stained with VE-cadherin and DAPI containing fluorescent nanoparticles. The original painting was created by Shae Shortt. View the article.
MAC_Bench/ACS/Story/Molecular Pharmaceutics/2024_10.txt
groundtruth
2024_10.txt
γ
MAC_Bench/ACS/Story/Molecular Pharmaceutics/2020_7.txt
vitg
2020_7.txt
Highlighting the cutting-edge, multidisciplinary, translational research in pharmaceutical sciences originating from researchers across Asia, the American Chemical Society journal Molecular Pharmaceutics is pleased to present a Virtual Special Issue titled "Advances in Molecular Pharmaceutical Research from Asia."  Wit...
MAC_Bench/ACS/Story/Molecular Pharmaceutics/2023_5.txt
vith
2023_5.txt
train
Nature Physics
20_2
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Physics/20_2.png
C
When networks get real Combining concepts from knot theory and statistical mechanics leads to a method for distinguishing between physical networks with identical wiring but different layouts. See Barabási et al. IMAGE: Alice Grishchenko. COVER DESIGN: Allen Beattie
MAC_Bench/Nature/Story/Nature Physics/17_11.txt
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17_11.txt
Charge on the bouncing barrier In our understanding of planetary formation, it is still unclear how millimetre-sized dust grains grow into centimetre-sized aggregates. Microgravity experiments now show that electrical charging of the grains leads to the formation of larger clumps. See Steinpilz et al. Image: Tobias Ste...
MAC_Bench/Nature/Story/Nature Physics/16_11.txt
vith
16_11.txt
Cellular energy budget How cells manage the internal energetic budget to drive mechanical and chemical dynamics is still an open question. Sheng Chen and collaborators show that the allocation of energy depends on how far the cell is from thermodynamic equilibrium. See Sheng Chen et al. Image: William Bement (Universit...
MAC_Bench/Nature/Story/Nature Physics/20_2.txt
groundtruth
20_2.txt
The formation of a shell Molluscs are capable of assembling layers of material in the shells around them with exquisite control. Synchrotron-based nanotomographic imaging of the structural evolution of this layer formation has now prompted a model that draws analogy with topological defect dynamics in liquid crystals A...
MAC_Bench/Nature/Story/Nature Physics/17_10.txt
vitg
17_10.txt
train
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
22_1
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_1.png
A
Diet and intestinal stem cells, inspired by the Review on p23 Cover design: Neil Smith
MAC_Bench/Nature/Story/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_1.txt
groundtruth
22_1.txt
Future of the gut microbiome, inspired by the Viewpoint on p830 Cover design: Laura Marshall
MAC_Bench/Nature/Story/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/21_1.txt
clip
21_1.txt
Diet and intestinal stem cells, inspired by the Review on p23 Cover design: Neil Smith
MAC_Bench/Nature/Story/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/22_2.txt
vitg
22_2.txt
Gut cell atlas, inspired by the Roadmap on p597. Cover design: Laura Marshall
MAC_Bench/Nature/Story/NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY/20_4.txt
ave_3
20_4.txt
train
Organometallics
2025_4
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Organometallics/2025_4.png
B
Modifying the steric properties of ligands enables tuning the reactivity of organometallic complexes. Although various methods have been developed to quantify the steric parameters of mononuclear complexes, these had not been validated for dinuclear complexes. The cover shows two copper atoms window shopping for dinucl...
MAC_Bench/ACS/Story/Organometallics/2023_24.txt
ave_2
2023_24.txt
s reactivity trend in activating C(spn)–X bonds mirrors that of a palladium catalyst. Reactivity increases by two distinct mechanisms: i) as the C(spn)–X bond becomes progressively weaker from X = F to Cl to Br to I, resulting in a more facile bond rupture, and ii) as the steric shielding at the pertinent carbon atom d...
MAC_Bench/ACS/Story/Organometallics/2025_4.txt
groundtruth
2025_4.txt
The future is shining bright for organometallics. This special issue shines light on photo-active organometallic complexes and their applications as photoredox catalysts.
MAC_Bench/ACS/Story/Organometallics/2024_9.txt
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2024_9.txt
What is the application? Consider how organometallic expertise can be extended to determine and realize new translational research opportunities. The diverse applications of organometallic chemistry featured in this Special Issue continue to inspire creative directions and novel approaches within the discipline.
MAC_Bench/ACS/Story/Organometallics/2024_5.txt
ave_1
2024_5.txt
train
Nature Machine Intelligence
6_7
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Machine Intelligence/6_7.png
D
Learning from human decision making Artificial intelligence and machine learning systems may surpass human performance on a variety of tasks, but they may also mimic or amplify human errors or biases. This issue of Nature Machine Intelligence features a Perspective describing decades of research by psychologists on the...
MAC_Bench/Nature/Story/Nature Machine Intelligence/1_9.txt
clip
1_9.txt
Intelligent collaboration within reach As robots are becoming skilled at performing complex tasks, the next step is to enable useful and safe interactions with humans. To effectively collaborate with and assist us, robots need to be able to understand human actions and intent. This issue of Nature Machine Intelligence ...
MAC_Bench/Nature/Story/Nature Machine Intelligence/1_12.txt
vitg
1_12.txt
Neural architecture search for computational genomics Applying deep learning models requires the tuning of network architectures for optimum performance, which can require substantial machine learning expertise. In this issue, Zijun Zhang et al. present a fully automated framework, AMBER, to design and apply convolutio...
MAC_Bench/Nature/Story/Nature Machine Intelligence/3_8.txt
ave_2
3_8.txt
Self-motion estimation with neuromorphic resonator networks Estimating position and movement relative to objects with vision is a challenging computational problem in robotics. Renner et al. propose a neuromorphic solution, aiming at low-power, brain-inspired machine vision for mobile robots. In this approach, event-ba...
MAC_Bench/Nature/Story/Nature Machine Intelligence/6_7.txt
groundtruth
6_7.txt
train
Trends in Biotechnology
42_6
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Biotechnology/42_6.png
A
Miniaturized in vitro bone models, known as "mini-bones," have emerged as powerful tools for studying physiology, disease mechanisms, and regenerative processes of bone, and for designing new bone-related therapies. In pages 910–928 of this issue, Fois and colleagues discuss how the mini-bones require small amounts of ...
MAC_Bench/Cell/Story/Trends in Biotechnology/42_6.txt
groundtruth
42_6.txt
LEGO® bricks are toys for kids that can be used to assemble mindblowing creations. In pages 1073–1087 of this issue, Boulter et al. discuss an alternative use of LEGO® bricks to design and assemble open-access scientific tools and systems for biotechnology and other fields of science. The LEGO® brick road depicted on t...
MAC_Bench/Cell/Story/Trends in Biotechnology/40_5.txt
vith
40_5.txt
Trends in Biotechnology is celebrating its 30th year of publishing exciting reviews in biotechnology. The coverimage shows microbes taking advantage of the occasion. Cover image made by Julien Husson and coverdesigned by Paige Shaklee.
MAC_Bench/Cell/Story/Trends in Biotechnology/31_11.txt
clip
31_11.txt
Trends in Biotechnology is celebrating its 30th year of publishing exciting reviews in biotechnology. The coverimage shows microbes taking advantage of the occasion. Cover image made by Julien Husson and coverdesigned by Paige Shaklee.
MAC_Bench/Cell/Story/Trends in Biotechnology/31_10.txt
ave_1
31_10.txt
train
ACS Sustainable Chemistry & Engineering
2025_6
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS Sustainable Chemistry & Engineering/2025_6.png
C
Lower right: Catalytic hydrogenation-esterification, which yields products favorable for subsequent upgrading, will benefit the high-grade utilization of sustainable biomass energy. (See J. Chen, Q. Cai, L. Lu, F. Leng, and S. Wang; DOI: 10.1021/acssuschemeng.6b02366.)
MAC_Bench/ACS/Story/ACS Sustainable Chemistry & Engineering/2017_9.txt
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2017_9.txt
Graphics from this issue of ACS Sustainable Chem. Eng.
MAC_Bench/ACS/Story/ACS Sustainable Chemistry & Engineering/2017_12.txt
vitg
2017_12.txt
The CO2 tree highlights the breadth of chemical compounds currently accessible from CO2 to illustrate its potential to serve as a carbon source for the future.
MAC_Bench/ACS/Story/ACS Sustainable Chemistry & Engineering/2025_6.txt
groundtruth
2025_6.txt
The cover art illustrates the innovative method of synthesizing spherical lignin-based 3D porous carbons (LSPCs). These ecofriendly spheres depict high surface areas and customizable micro/mesopores. With their impressive performance in supercapacitors and sodium-ion batteries, these materials significantly advance in ...
MAC_Bench/ACS/Story/ACS Sustainable Chemistry & Engineering/2024_47.txt
vith
2024_47.txt
train
ACS Chemical Neuroscience
2024_5
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_5.png
B
A gold-star-coated aluminum substrate-based SERS immunoassay platform for the selective detection of blood-based biomarkers Aβ40, Aβ42, p-Tau, and t-Tau of Alzheimer’s disease (AD). SERS spectral data augmented by the machine learning technique yielded high sensitivity of the order of an attomolar concentration of the ...
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2024_1.txt
ave_2
2024_1.txt
Interpreting immune cell behavior and signaling is critical to understanding Alzheimer's neuroinflammation. Preventing neurodegeneration is the goal of reorienting attention from Aβ synthesis to immune-mediated clearance. Successfully addressing obstacles such as negative immune reactions might result in notable progre...
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2024_5.txt
groundtruth
2024_5.txt
10.1021/acschemneuro.0c00004
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2020_21.txt
clip
2020_21.txt
Discovery of the peptide therapeutics targeting amyloid formation in neurodegenerative diseases, using the synergistic combination of yeast display and phage display techniques.
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2023_6.txt
ave_1
2023_6.txt
val
BDJ Student
32_1
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/BDJ Student/32_1.png
A
BDJ Student - King's College London takeover Welcome to this very special edition of BDJ Student! In 2025, three dental schools will be taking over each of our issues. In this January edition, I'm delighted to introduce the King's College London takeover, packed full of interesting and insightful articles from one of ...
MAC_Bench/Nature/Story/BDJ Student/32_1.txt
groundtruth
32_1.txt
Volume 28 | Issue 3 How can we integrate oral health with global health? The cover feature in this edition's BDJ Student asks - and answers - that very question Cover illustration by Cat Sims
MAC_Bench/Nature/Story/BDJ Student/28_1.txt
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28_1.txt
Vol 31 | Issue 2 In this spring issue of BDJ Student, our lead feature takes a closer look at four dental professionals who have taken their clinical knowledge and applied it outside the practice Cover illustration by Cat Sims
MAC_Bench/Nature/Story/BDJ Student/31_2.txt
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31_2.txt
Volume 28 | Issue 1 In this issue we hear from new BDA President Russ Ladwa, detail the career options for dentists in the UK and delve into oral medicine conditions you need to know about Cover illustration by Cat Sims
MAC_Bench/Nature/Story/BDJ Student/28_3.txt
vith
28_3.txt
train
Science Robotics
10_99
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science Robotics/10_99.png
A
ONLINE COVER Biohybrid Robots—Controlling Robotic Hand Movement with Muscle Tissue. Biohybrid robots provide the advantage of combining muscle tissue derived from cells as well as synthetic components. These muscle tissues can be controlled to generate contractile forces necessary to provide linear movement of joints. ...
MAC_Bench/Science/Story/Science Robotics/10_99.txt
groundtruth
10_99.txt
ONLINE COVER A Model of Oneself. Robots, like humans and animals, require self-models to be able to anticipate and plan future actions. Chen et al. developed a method that enables a robot arm to model its morphology and kinematics using an approach based on query-driven visual self-modeling. This month’s cover is a mul...
MAC_Bench/Science/Story/Science Robotics/7_68.txt
vitg
7_68.txt
ONLINE COVER Soft Robotics Across Scales. Extensive research, from materials engineering to whole systems, is expanding the boundaries of robotics to create stretchy, flexible, touch-feedback electronics; advanced microelectromechanical systems; and shape-morphing and self-propelling devices. Umrao et al. designed Ti3C...
MAC_Bench/Science/Story/Science Robotics/4_33.txt
vith
4_33.txt
ONLINE COVER Piano Forte. Human hands are complex and agile, but most robotic end effectors are simple and bulky. Hughes et al. used 3D-printing technology to create robotic devices that mimic human hands, with stiff skeletal frames surrounded by flexible "ligaments" controlling movement at joints. They varied ligament...
MAC_Bench/Science/Story/Science Robotics/3_25.txt
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3_25.txt
train
Developmental Cell
59_22
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Developmental Cell/59_22.png
B
On the cover: This image shows a developing human forebrain organoid at day 60, which has a “tree-like” structure. Neural progenitor cells are marked by SOX2 (green), lysosomes are marked by LAMP1 (white), and nuclei are marked by DAPI (blue). During the development of embryonic neocortex, there are abundant endolysoso...
MAC_Bench/Cell/Story/Developmental Cell/59_24.txt
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59_24.txt
On the cover: Confocal microscopy image of a mouse embryonic pancreatic explant showing pancreatic epithelial branches (green) and acinar progenitor cells (purple). At this stage, pancreatic duct cells are marked by Prox1 (green) and form secondary branches, which end with acinar structures positive for Integrin alpha6...
MAC_Bench/Cell/Story/Developmental Cell/59_22.txt
groundtruth
59_22.txt
On the cover: Cell intercalation generates directed forces that elongate the vertebrate body axis during early development. In this image, a heatmap quantifying tissue-scale pushing forces is superimposed over an image of polarized, intercalating cells. For more about how Arvcf Catenin is required specifically for the ...
MAC_Bench/Cell/Story/Developmental Cell/57_16.txt
vith
57_16.txt
On the cover: Developmental Cell publishes papers representing a full range of cell biology and development, from molecular mechanism to organismal pathophysiology. The spiraling elements depicted on the cover of this month's tenth anniversary issue suggest a continuum of relationships amongst these intertwined discipl...
MAC_Bench/Cell/Story/Developmental Cell/21_6.txt
vitg
21_6.txt
test
Trends in Biochemical Sciences
49_1
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_1.png
B
In this issue of Trends in Biochemical Sciences, women scientists are the primary authors of the Opinion and Review articles. From Anna Marabotti and colleagues, “Standardizing macromolecular structure files: further efforts are needed”; from Ilaria Elia et al, “The metabolic cross-talk between cancer and T cells”; fro...
MAC_Bench/Cell/Story/Trends in Biochemical Sciences/48_6.txt
vitg
48_6.txt
Small heat shock proteins (sHsps) protect the proteome against deleterious effects of protein unfolding, catching non-native proteins before they aggregate and precipitate. On pages 1063–1078 in this issue, Johannes Buchner and colleagues describe the structural and functional principles of sHsp oligomers and what make...
MAC_Bench/Cell/Story/Trends in Biochemical Sciences/49_1.txt
groundtruth
49_1.txt
On The Cover: Molecular dynamics (MD) simulations can be used to visualize fluctuations of biological macromolecules at high resolution, though are often only represented as static figures in published literature. On pages 902–913 of this issue of Trends in Biochemical Sciences, Drs. Peter Hildebrand, Alexander Rose, a...
MAC_Bench/Cell/Story/Trends in Biochemical Sciences/44_2.txt
vith
44_2.txt
In this issue of Trends in Biochemical Sciences on pages 39–51, Olarte et al. describe two pathways, the CYTOLD and ERTOLD pathways, for directing protein to the surface of lipid droplets (LDs). The cover is an artistic depiction of lipid droplets budding from the endoplasmic reticulum (ER), a membrane network where li...
MAC_Bench/Cell/Story/Trends in Biochemical Sciences/47_14.txt
clip
47_14.txt
train
Trendsin Neurosciences
47_4
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trendsin Neurosciences/47_4.png
B
On The Cover: In this issue of Trends in Neurosciences, Jay Schulkin and Peter Sterling review recent evidence for allostasis, the efficient, anticipatory regulation of physiology. The brain predicts what will be needed and, via myriad descending control mechanisms, including hypothalamus and cerebral cortex, directs t...
MAC_Bench/Cell/Story/Trendsin Neurosciences/42_3.txt
vitg
42_3.txt
Synucleinopathies are characterized by neuronal loss accompanied by α-synuclein accumulation in the brain. While research conventionally focused on brain pathology, there is growing evidence for peripheral alterations in synucleinopathies, including in erythrocytes, which are rich in α-synuclein. Erythrocyte-derived ex...
MAC_Bench/Cell/Story/Trendsin Neurosciences/47_4.txt
groundtruth
47_4.txt
Pyramidal neurons with active dendritic properties are found ubiquitously across the neocortex. On pages 141–151, Matthew Larkum presents the hypothesis that both the cellular properties and architecture of the cortex are tightly coupled, suggesting a powerful operating principle of the cortex. The cover image shows la...
MAC_Bench/Cell/Story/Trendsin Neurosciences/36_10.txt
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36_10.txt
Normal development and functioning of the nervous system is critically dependent upon interaction with the immune system. Recent research at the interface of neuroscience and immunology has revealed the ways in which reciprocal neuroimmune interactions are important for many brain-behavior relationships. This Special I...
MAC_Bench/Cell/Story/Trendsin Neurosciences/38_4.txt
vith
38_4.txt
train
Trends in Plant Science
29_11
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Plant Science/29_11.png
C
Individual plant and enemy species (or populations) are reciprocally interacting in a way that shapes their traits and evolution. This concept of specificity in plant–herbivore and plant–pathogen interactions is central to this special issue of Trends in Plant Science. Why is it that most herbivores and pathogens attac...
MAC_Bench/Cell/Story/Trends in Plant Science/17_9.txt
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17_9.txt
Enormous societal challenges, such as feeding and providing energy for a growing population in a dramatically changing climate, necessitate technological advances in plant science. On pages 303–310 Seung Y. Rhee and colleagues propose that, complementary to the efforts towards understanding the cellular diversity in hu...
MAC_Bench/Cell/Story/Trends in Plant Science/24_10.txt
vitg
24_10.txt
Precise communication between the pollen tube and the synergid cells within the ovule is essential to coordinate pollen tube rupture, followed by delivery and reception of the sperm cells. Alice Baillie and colleagues provide insight into the complicated interaction between the receptor-like kinases involved, and their...
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Two papers by Christoph-Martin Geilfus and colleagues and Muzammil Hussain, Dominique Van Der Straeten and colleagues discuss the recent breakthrough discovery that stressed plants emit various informative ultrasonic sound signals, which can be categorized according to plant species, stress type, and stress severity. T...
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Nature Reviews Materials
9_9
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Materials/9_9.png
D
This month, we celebrate the fifth anniversary of Nature Reviews Materials. In our editorial, we look back over this time and contemplate the future. See Editorial. Cover: Charlotte Gurr
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CO2 electroreduction aims to decarbonize by converting CO2 and clean energy into chemicals. To have an impact, this technology should be scaled up into the gigatonne conversion range, which involves challenges related to resource and material scalability bottlenecks. The cover shows an artistic representation of the im...
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Microscale robots' unique active motion enables their precise navigation in different aqueous biological or environmental media. The image shows an artist’s impression of microrobots using photocatalysis to degrade chemical and biological warfare agents for environmental remediation. See Chen C. et al Cover image: Davi...
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Crystallization of soft materials often follows pathways not envisioned in classical theories of crystallization, instead passing through disordered, amorphous, or dense liquid precursors. The recent emergence of techniques to probe these pathways with minimal damage has led to a growing knowledge about these pathways....
MAC_Bench/Nature/Story/Nature Reviews Materials/9_9.txt
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Current Biology
34_10
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Current Biology/34_10.png
B
On the cover: A large number of gray reef sharks fight over a grouper. Pristine marine locations are rare and usually host a large number of sharks, raising the question of how such a high predator density can be supported by local food. In this issue, Mourier et al. (pages 2011–2016) report extremely high shark biomas...
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On the cover: White shark (Carcharodon carcharias) swimming in the clear waters around Guadalupe Island (Mexico). In this issue, Wagner et al. use genome-wide sequencing to show global white shark populations are divided into three distinct genetic lineages: Atlantic/Mediterranean, North Pacific, and Indo-Pacific. Thes...
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On the cover: With this issue, Current Biologycompletes its twentieth year. Since its origins as a journal publishing “dispatches from the front lines of biology,” Current Biologyhas continuously expanded in terms of both paper formats and breadth of subjects covered. We hope the journal will continue to evolve and loo...
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On the cover: In this issue, Skomal et al. (pages 1019–1022) use satellite archival tags and a novel geolocation technique to demonstrate that the world's second largest fish, the basking shark, makes ocean basin-scale movements in the western Atlantic over a much broader geographic range than previously thought. The a...
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Trends in Cancer
10_9
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Cancer/10_9.png
D
Variations in cancer incidence fuel the debate on the relative contributions of intrinsic vs extrinsic factors. On pages 409–415 in this issue, Thomas et al. add an extra piece to the puzzle by exploring the concept of evolutionary ecology in oncogenesis, and discuss how an organ ecosystem and its contribution to Darwi...
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Barcoding technologies are enabling the quantification of heterogeneous populations as well as changes in phenotypic states of cancer cells. In this issue, Howland and Brock discuss various barcoding technologies that are providing unique opportunities to understand tumor evolution in the context of selective pressures...
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Fast-paced advances in single-cell sequencing technologies allow unprecedent ways to probe tumor development, evolution, and response to therapies. On pages 13–19, González-Silva et al. discuss the opportunities and roadblocks to use these technologies to unravel the complexities of tumor heterogeneity, and translation...
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In the evolving era of cancer immunotherapy, combination strategies are becoming ever more effective in overcoming challenges associated with PD-1 monotherapy. In this issue, Hashimoto et al. discuss the potential of PD-1/IL-2 combination regimen in enhancing anti-cancer therapy efficacy through shaping the differentia...
MAC_Bench/Cell/Story/Trends in Cancer/10_9.txt
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Acta Pharmacologica Sinica
45_6
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Acta Pharmacologica Sinica/45_6.png
C
Cover Credit: DZ2002, a reversible inhibitor of type III S-adenosyl-L-homocysteine hydrolase, attenuates TNF-α-induced NF-κB signaling by suppressing the degradation and phosphorylation of IκB, along with NF-κB p65 phosphorylation and nuclear translocation. Additionally, DZ2002 inhibits the activation of molecules in t...
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Cover Credit: In this cover article, Zhou et al. constructed a novel mechanistic quantitative systems pharmacology model describing the underlying pathophysiological processes of HER2+BC, from ligand-receptor binding to downstream signaling and finally to tumor growth, while incorporating the distinct modalities and me...
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Cover Credit: Suppressive tumor immune microenvironment (TIME) contributes to tumor progression and immunotherapy failure. Noninvasive radiofrequency radiation (RFR) exposure reshapes TIME into an antitumor phenotype by altering the transcription profile of tumor-infiltrating immune cells in pulmonary metastatic melano...
MAC_Bench/Nature/Story/Acta Pharmacologica Sinica/45_6.txt
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Cover Credit: Reduction-activatable PROTAC prodrug nanoparticles for tumor-targeted protein degradation and anticancer therapy. The reduction-activatable PROTAC prodrug nanoparticles (NPs) were engineered by self-assembly of the PROTAC-conjugated amphiphilic diblock copolymer and further functionalized with a CRGDK lig...
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Trends in Cancer
10_5
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Cancer/10_5.png
D
We invite readers to explore the newest addition to the Trends collection Trends in Cancer, which aims to cover a range of topics in cancer research including the latest developments in basic, translational and clinical sciences, pharma R&D, technology, ethics, and policy. The inaugural issue of Trends in Cancer tackle...
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This Special Issue on Physical Sciences in Oncology celebrates recent advances and new scientific frontiers in a rising field that is bringing back the application of physical principles to biology, and fostering a wide-angle cross-disciplinary perspective on cancer. Cover design by Imdat As.
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The cover image depicts a masked face harbouring an intricately woven web of connections, signifying the virtual global network that helps cultivate a feeling of ‘togetherness’ in the backdrop of a pandemic threatening to keep us apart. The theme, ‘Apart, Together’ symbolises the many experiences of members of the scie...
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Traditional approaches to understand mental health in cancer survivors often involve the classification of psychopathology into discrete disorders. However, this approach has faced mounting criticism. In this issue, Haywood et al. propose that the hierarchical dimensional approach (HiTOP model) diminishes stigma, consi...
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Trends in Biochemical Sciences
49_7
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Biochemical Sciences/49_7.png
D
In this issue of Trends in Biochemical Sciences on pages 39–51, Olarte et al. describe two pathways, the CYTOLD and ERTOLD pathways, for directing protein to the surface of lipid droplets (LDs). The cover is an artistic depiction of lipid droplets budding from the endoplasmic reticulum (ER), a membrane network where li...
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On The Cover: Molecular dynamics (MD) simulations can be used to visualize fluctuations of biological macromolecules at high resolution, though are often only represented as static figures in published literature. On pages 902–913 of this issue of Trends in Biochemical Sciences, Drs. Peter Hildebrand, Alexander Rose, a...
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In this issue of Trends in Biochemical Sciences, women scientists are the primary authors of the Opinion and Review articles. From Anna Marabotti and colleagues, “Standardizing macromolecular structure files: further efforts are needed”; from Ilaria Elia et al, “The metabolic cross-talk between cancer and T cells”; fro...
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Osmotic stress conditions cause changes in the physicochemical properties of the cellular environment, including macromolecular crowding. Recent progress has shed light on how cells sense such environmental perturbations (e.g. temperature, pH, and crowding). On pages 480–493 in this issue, Meneses-Reyes et al. discuss ...
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Science Signaling
2007_379
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science Signaling/2007_379.png
B
ONLINE COVER This week features a Research Article that describes a calcium-accumulating region in Orai channels that is important for ion flux at low concentrations of extracellular calcium. The image shows a snapshot of a molecular dynamics simulation of this region of the channel. The yellow balls are calcium ions. ...
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COVER This week features a Perspective on nonconventional functions of the phagocytic NADPH oxidase (NOX2). The image depicts a neutrophil extracellular trap (NET), formation of which depends on reactive oxygen species generated through NOX2 activity. [Image: Volker Brinkmann, Max-Planck Institute for Infection Biology...
MAC_Bench/Science/Story/Science Signaling/2007_379.txt
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ONLINE COVER This week, Santi et al. report that cancer-associated fibroblasts release matrix-bound vesicles that transfer proteins to endothelial cells, resulting in enhanced monocyte adhesion to endothelial cells. The image shows a three-dimensional reconstruction of endothelial cells co-cultured with cancer-associat...
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ONLINE COVER This week features a Research Article that shows how neuronal activity is coordinated by a network formed by gap junction–linked astrocytes. The image shows bursting activity in a hippocampal slice from a wild-type mouse. [Image: Elena Dossi (Center for Interdisciplinary Research in Biology, Collège de Fra...
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Nature Physics
20_3
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Physics/20_3.png
B
Braided anyons An interferometer device is used to detect the quantum-mechanical phase that is gained when two anyons are braided around each other. The fractional value of the phase proves that these quasiparticles are neither bosons nor fermions. Manfra, Article IMAGE: James Nakamura and Michael Manfra, Purdue Univer...
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Electronic motion up close Charge density waves are wave-like patterns in a material’s electron density that can behave collectively. Shaoxiang Sheng et al. show a direct real-space observation of these collective dynamics at the atomic scale in the transition metal dichalcogenide 2H-NbSe2. Their technique utilizes a t...
MAC_Bench/Nature/Story/Nature Physics/20_3.txt
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Odd viscosity A chiral fluid comprising spinning colloidal magnets exhibits macroscopic dynamics reminiscent of the free surface flows of Newtonian fluids, together with unique features suggestive of Hall—or odd—viscosity. See Irvine et al. Image: Vishal Soni, Ephraim Bililign, Sofia Magkiriadou, University of Chicago....
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Controlled turbulence Turbulence is generated using vortex rings as building blocks in a quiescent environment. See Matsuzawa et al. and Research Briefing Image: Takumi Matsuzawa, IrvineLab, University of Chicago. Cover Design: Amie Fernandez.
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Nature Reviews Endocrinology
20_9
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Endocrinology/20_9.png
D
Our April issue includes articles on circadian rhythms and exercise, innervation of adipose tissue, enteroendocrine cells and gut hormones and the function of motilin. Pancreatic islet image supplied by Shih-Jung Peng and Shiue-Cheng Tang at Department of Medical Science, National Tsing Hua University, Taiwan. Cover de...
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/15_9.txt
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The ageing thyroid, inspired by the Review on p5. Cover design: Jennie Vallis
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COVER: Modelling endometrial diseases, inspired by the Review on p727. Cover design: Jennie Vallis.
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/18_1.txt
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How to manage iatrogenic adrenal insufficiency, inspired by the Review on p209. Cover design: Jennie Vallis
MAC_Bench/Nature/Story/Nature Reviews Endocrinology/20_9.txt
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Cell Systems
15_7
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Cell Systems/15_7.png
A
On the cover: Illustration showing simulations of tumor growth arranged as the two strands of a DNA helix, shattered by the emblematic double strand break induced by PARP inhibitors. The simulations (strands) compare two adaptive strategies: as the tumor responds and regrows under treatment (blue lines), doses are eith...
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On the cover: Cell Systems turns one. This issue features a Focus on RECOMB (Li et al., 21–34; Sefer et al., 35–42; El-Kebir et al., 43–53; Simmons et al., 54–61; Dao et al., 62–70) and our new Tool article format (Durand et al., 95–98 and 99–101; Liepe et al., 102–107) and badge (Ritchie et al., 71–82). They represent...
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On the cover: Cell Systems is doing its part to keep the wheels of the scientific endeavor turning during the COVID-19 pandemic. In this issue, Editor-in-Chief Quincey Justman (307) describes our approach. Image credit: denisgo, Getty Images.
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On the cover: The two-dimensional representation of protein sequence space learned by a recurrent geometric network, a deep learning model that predicts protein structure directly from sequence. Contours correspond to different protein folds as they are organized inside the model's internal representation. In this issu...
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Nature Nanotechnology
19_5
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Nanotechnology/19_5.png
A
Pinpoint doping for polymers The cover shows an atomic force microscopy image of nanoscale doped plastic polymers achieved through precise electrochemical ion implantation. See Lanyi Xiang et al. Image: Chong-an Di, Institute of Chemistry, Chinese Academy of Sciences. Cover design: Debbie Maizels
MAC_Bench/Nature/Story/Nature Nanotechnology/19_5.txt
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Superlubricity occurs when friction between two sliding surfaces almost vanishes. This phenomenon has been observed so far only for small specimens that are a few micrometres wide at most. Yingying Zhang and colleagues have now observed superlubricity between centimetre-long concentric carbon nanotubes (schematically s...
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Lasing from bulk nanocrystals The image depicts surface-emitting lasers consisting of a bulk nanocrystal layer covered by a 2D photonic crystal grating. See Geiregat Image: Ivo Tanghe, Ghent University. Cover design: Valentina Monaco
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Plasmonics with nanocrystals. Cover design by Karen Moore. Article by Tao et al .
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Trends in Genetics
40_9
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Genetics/40_9.png
D
Barbara McClintock once said “With the tools and the knowledge, I could turn a developing snail's egg into an elephant. It is not so much a matter of chemicals because snails and elephants do not differ that much; it is a matter of timing the action of genes.” This Focus issue of Trends in Genetics delves into studies ...
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In this special issue of Trends in Genetics, we turn the lens on ourselves. The articles this month focus on human genetics, with topics ranging from resources and methods to make the most of the explosion of sequencing data to evolutionary questions about mutation rates and how selection acts through pregnancy.
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This Special Issue of Trends in Genetics covers a range of themes related to organogenesis, from the formation of the central nervous system to the evolution of the insect eye. The articles in this issue highlight the commonalities of organ formation that are shared across species and kingdoms, and provide insight on t...
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In this issue: Genomic resources and profound ecological knowledge make Littorina snails useful models for speciation studies. Ecotypes and closely related species adapted to different rocky-shore environments form hybrid zones where reproductive isolation can be investigated. In this issue, Kerstin Johannesson and co-...
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Journal of Chemical Education
2021_10
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Journal of Chemical Education/2021_10.png
D
Evoking affective responses from students studying chemistry may heighten their curiosity and further engage their interest in the subject, motivating them to delve deeper. In "Integrating Aesthetics Education into Chemistry Education: Students Perceive, Appreciate, Explore, and Create the Beauty of Chemistry in Scient...
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Modern chemistry programs must include the skills and techniques that enable their graduates to perform experiments safely. In response to a call for papers, scientists and educators from around the world have contributed articles to the Journal of Chemical Education's Special Issue on Chemical Safety Education: Method...
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The cover images are from one of the many videos available at the JCE Chemical Education Xchange Web site (ChemEd X, http://www.jce.divched.org/). The Journal of Chemical Education’spartner Web site aims to foster sharing of digital resources, information, and ideas among chemical educators. (Images from Chemistry Come...
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With resurgent lunar exploration and expansion of the commercial space sector, serious scholarship, planning, and resources have focused on extracting and using lunar materials to sustain activity in space. In "Lunar Resource Harvesting and Manufacturing: Rich Content for the Chemistry Classroom" (DOI: 10.1021/acs.jche...
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Nature Mental Health
2_5
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Mental Health/2_5.png
D
Climate mental health The February cover is a moody depiction of climate mental health. Intended to invoke the idea of the interplay among Gaia (the spirit of Earth), nature and humanity, the blue tones also reference the Connecting Climate Minds project. As a means for placing mental health prominently in climate agen...
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Earth, brain and health Our October issue features a Comment announcing the Earth, Brain and Health Commission that has been convened with Nature Mental Health. By applying innovative cutting-edge technology, such as remote-sensing satellite data, with other sociodemographic and neuroimaging data, the commission seeks ...
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Mental health awareness Each May, campaigns take place that are designed to draw awareness to mental health, to reduce stigma and to champion inclusivity. This month’s issue cover features a green ribbon — the international symbol that is associated with observing Mental Health Awareness Month. Not only is green the th...
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Countries and culture — mental health in context Our August issue cover highlights how crucial our connections with countries and culture are and how they can meaningfully shape our mental health. In a sense, they are influences imprinted on brains and minds. From ancient philosophers and theologians to modern mental h...
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Cell Reports Physical Science
5_4
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Cell Reports Physical Science/5_4.png
B
On the cover: A visual celebration of Cell Reports Physical Science’s fifth anniversary, featuring all of our covers from Volume 1, Issue 1 to December 2024’s Volume 5, Issue 12. We’d like to thank Cell Press’s own Philip Krzeminski for his help in creating this beautiful cover.
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On the cover: The cover of this month’s issue of Cell Reports Physical Science summarizes the research of Li et al. on the preparation of multiscale hydrogels. The background represents a hydrogel’s macroporous structure, which provides space for cells. The hydrogel (upper left) affects mesenchymal stem-cell fate with ...
MAC_Bench/Cell/Story/Cell Reports Physical Science/5_4.txt
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On the cover: A visual celebration of Cell Reports Physical Science’s fifth anniversary, featuring all of our covers from Volume 1, Issue 1 to December 2024’s Volume 5, Issue 12. We’d like to thank Cell Press’s own Philip Krzeminski for his help in creating this beautiful cover.
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On the Cover: We celebrate our first issue with this eye-catching cover, designed by the Cell Press creative team, representing our first “drop” of papers and signifying the birth of a new journal and our expansion into the fundamental and applied physical sciences.
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Cancer Cell
42_12
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Cancer Cell/42_12.png
C
On the cover: To holistically describe and comprehensively characterize cancer cells and the surrounding tumor microenvironment, Bagaev et al. (pp. 845–865) analyzed transcriptomes of over 10,000 cancer patients. This led to the identification of four distinct subtypes of tumor microenvironment that are conserved acros...
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On the cover: Cancers sharing the same clinical diagnosis often harbor striking differences at the molecular level. Such is the case for diffuse large B cell lymphoma (DLBCL). A careful examination of different DLBCL molecular subsets reveals distinct metabolic signatures. Depicted here is a close-up of an “OxPhos” can...
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On the cover: Routy et al. review the microbiota research in the context of melanoma. The cover image demonstrates the interplay between melanoma cancer cells and microbiota visually. An intricate network of lines creates connections that symbolize the link between intestinal bacteria and melanoma, highlighting the rec...
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On the cover: From Dangaj and Coukos et al. (pp. 885–900), cold tumors (ice floe side) are characterized by low chemokine CCL5 expression and are immune desert. By contrast, hot tumors (tropical side) express high levels of CCL5 and CXCL9, which cooperate to recruit tumor-reactive T cells rendering the tumor microenvir...
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NATURE MEDICINE
31_1
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE MEDICINE/31_1.png
A
30th anniversary issue: the Future of Medicine As Nature Medicine turns 30 years old, we will, throughout 2025, be looking at the future of medicine. In this first issue, we turn our attention to next-generation drug discovery. Image and cover design: Alex Whitworth
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In 2004, Nature Medicine enters its tenth year of publication, continuing our mission to serve the biomedical research community as the venue for top-flight primary research articles, news and perspectives. The cover image commemorates our anniversary year with a collage of covers spanning our publication history. (Gra...
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This month Nature Medicine features a collection of articles focusing on regenerative medicine (pp 814–880). Cover image: "My Life as a Hill" by Pamela Goode
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Medicine in the digital age As Nature Medicine celebrates its 25th anniversary, we bring our readers a special Focus on Digital Medicine that highlights the new technologies transforming medicine and healthcare, as well as the related regulatory challenges ahead. See Focus Image credit: Peter Crowther. Cover design: Er...
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Structure
32_3
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Structure/32_3.png
A
On the cover: Synaptotagmin-1 C2A and C2B domains bind to model lipid bilayers mimicking the synaptic plasma membrane (C2B) and the synaptic vesicle membrane (C2A). A native mass spectrum of Synaptotagmin-1 binding to DOPS at different stoichiometries is shown below the plasma membrane plane. Bender et al. combined nat...
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On the cover: In this special issue, we celebrate Structure’s 30th anniversary with a collection of reviews that highlight recent developments in different areas of structural biology. We asked structural biologists what to expect for the next decade in our Voices article. Cover image drawn by Julie Sung (scienti...
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On the cover: The image shows a rendering of the structure of the Haliangium ochraceum bacterial microcompartment shell, the cryo-electron microscopy structure of which Greber et al. (pp. 749–763) present in a paper in this issue of Structure. The shell is composed of different types of BMC proteins, which are shown in...
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On the cover: In this issue, Huo et al. (pp. 1270–1279) combined X-ray crystallography and electron microscopy to get the complete high-resolution open structure of group II chaperonin from Acidianus tengchongensis strain S5 and elucidated the detailed conformational changes from open to closed state. The cover shows t...
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Science Immunology
9_99
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science Immunology/9_99.png
D
ONLINE COVER Sugarcoated Vaccine. This month's cover illustration depicts the trimeric pre-fusion (pre-F) protein of respiratory syncytial virus (RSV) found in an engineered nanoparticle vaccine construct. Swanson et al. describe the synthesis and preclinical testing of an RSV vaccine candidate consisting of eight of t...
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ONLINE COVER Turning Anti–PD-1 on Its Head. This month's cover illustration is a 3D rendition of pembrolizumab, one of several therapeutic monoclonal antibodies against human PD-1 being used for cancer immunotherapy. Based on results with a new conditional allele of the Pdcd1 gene in mice, Strauss et al. report that PD...
MAC_Bench/Science/Story/Science Immunology/5_43.txt
vith
5_43.txt
ONLINE COVER Promoting Tolerance. Depicted here is a type 1 regulatory T (TR1) cell (left) interacting with a dendritic cell (top right, dark purple) and an interleukin-27 (IL-27)–secreting macrophage (bottom right, light purple). Zhang et al. report that IL-27–driven commitment of T cells to the TR1 cell lineage limit...
MAC_Bench/Science/Story/Science Immunology/2_10.txt
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2_10.txt
ONLINE COVER IgE Plasma Cells Are Cut from a Different Cloth. Immunoglobulin E–producing plasma cells (IgE PCs) are key players in allergic reactions and are an attractive target for the treatment of allergic diseases. A deeper understanding of IgE PC phenotypic and transcriptional profiles is needed, however. Vecchion...
MAC_Bench/Science/Story/Science Immunology/9_99.txt
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9_99.txt
test
NATURE REVIEWS DRUG DISCOVERY
24_2
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/24_2.png
C
Targeting neutrophils, inspired by the Review on p253. Cover design: Susanne Harris.
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/19_9.txt
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19_9.txt
Immune targets for antidepressants, inspired by the Review on p224. Cover design: S. Harris
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/21_10.txt
clip
21_10.txt
N-of-1 therapies, inspired by the Review on p40. Cover design: S. Harris
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/24_2.txt
groundtruth
24_2.txt
Deuterium in drug discovery, inspired by the Review onp562. Cover design: S. Harris
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/22_6.txt
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22_6.txt
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NATURE REVIEWS MICROBIOLOGY
22_8
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_8.png
A
Alternatives for treating antibiotic-resistant pathogens, inspired by the Review on p262. Cover design: Philip Patenall.
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/22_8.txt
groundtruth
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Machine learning for microbiologists, inspired by the Review on p191. Cover design: Philip Patenall.
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/22_9.txt
vith
22_9.txt
Bacterial biofilms, inspired by the Focus issue. Cover design: Philip Patenall
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/20_3.txt
vitg
20_3.txt
Celebrating 20 years of Nature Reviews Microbiology. Cover design: Neil Smith.
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/21_3.txt
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21_3.txt
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Science Robotics
9_88
Which of the following options best describe the cover image?
MAC_Bench/Science/Cover/Science Robotics/9_88.png
D
ONLINE COVER Special Issue on Robots in the Wild. Robots have been successfully deployed in a wide range of domains–including land, sea, air, and space–for a variety of applications such as search and rescue, oceanography, wildlife surveys, and space exploration. In this issue, Zhou et al. have developed a trajectory p...
MAC_Bench/Science/Story/Science Robotics/7_66.txt
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ONLINE COVER Special Issue on Autonomy and AI in Robotics. A team of legged robots can efficiently explore unstructured terrains with task-level autonomy. Arm et al. report on a robot team comprising a “scout” that can identify potential scientific targets in an environment, a “hybrid” that collects data from the targe...
MAC_Bench/Science/Story/Science Robotics/8_80.txt
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ONLINE COVER From the Tip Leveraging the flexibility that is possible when using soft materials, Hawkes et al. used pneumatics to extend the tip of a robot over an extended distance. They inflated chambers on only one side of the robot to make it turn. An onboard camera connected to a feedback loop allowed the robot to...
MAC_Bench/Science/Story/Science Robotics/2_8.txt
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2_8.txt
ONLINE COVER Snake-Like Robot—A Robot for Autonomous Navigation and Exploration of Icy Terrain. Vaquero et al. report on a snake-like robot, Exobiology Extant Life Surveyor (EELS), that was developed to autonomously explore icy moons such as Enceladus. EELS has a perception head containing sensors and cameras for detec...
MAC_Bench/Science/Story/Science Robotics/9_88.txt
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Journal of Medicinal Chemistry
2024_21
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Journal of Medicinal Chemistry/2024_21.png
C
Light activation to inhibit prolyl hydroxylase 2, subsequently stabilizing hypoxia-inducible factor and promoting expression of the target gene. (Zhang, X.; et al. J. Med. Chem. 2019, 62, DOI: 10.1021/acs.jmedchem.9b00688)
MAC_Bench/ACS/Story/Journal of Medicinal Chemistry/2019_9.txt
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2019_9.txt
Flygare, J. A.; Beresini, M.; Budha, N.; Chan, H.; Chan, I. T.; Cheeti, S.; Cohen, F.; Deshayes, K.; Doerner, K.; Eckhardt, S. G.; Elliott, L. O.; Feng, B.; Franklin, M. C.; Reisner, S. F.; Gazzard, L.; Halladay, J.; Hymowitz, S. G.; La, H.; LoRusso, P.; Maurer, B.; Murray, L.; Plise, E.; Quan, C.; Stephan, J.-P.; Youn...
MAC_Bench/ACS/Story/Journal of Medicinal Chemistry/2012_15.txt
vith
2012_15.txt
This research utilizes phytochemical nanoparticles loaded on 3D-printed tricalcium phosphate scaffolds for the treatment of critical bone defects.
MAC_Bench/ACS/Story/Journal of Medicinal Chemistry/2024_21.txt
groundtruth
2024_21.txt
The novel clinical FLAP inhibitor AZD5718 inhibiting FLAP in coronary artery for treatment of coronary artery disease. (Pettersen, D.; et al. J. Med. Chem. 2019, 62, DOI: 10.1021/acs.jmedchem.8b02004) View the article.
MAC_Bench/ACS/Story/Journal of Medicinal Chemistry/2019_16.txt
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2019_16.txt
train
Matter
7_4
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Matter/7_4.png
C
On the cover: As reported by Y.S. Zhang and colleagues in this issue of Matter, a cryobioprinting method is optimized for fabricating freeform storable tissue constructs with shelf availability by taking advantage of the designed cryoprotective bioinks to maintain the functionality of embedded cells during the cryobiop...
MAC_Bench/Cell/Story/Matter/5_11.txt
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5_11.txt
On the cover: This issue of Matter marks the inaugural “Pieces of Matter” issue, with a collection of six invited Perspectives, five featured in this issue (see the contributions by Buonassisi, Jen/Yip, Loi, Stranks, Walsh, and Yang) with a focus on a single materials system: perovskites. The cover, contributed by co-e...
MAC_Bench/Cell/Story/Matter/4_1.txt
vitg
4_1.txt
On the cover: This month's cover from Hsu and colleagues depicts a red-colored biomaterials film wrapped in a spiral pattern to look like a rose, sitting in a menstrual cup. The work describes the development of an eco-friendly, blood-absorbent biomaterial that improves the performance of menstrual products by minimizi...
MAC_Bench/Cell/Story/Matter/7_4.txt
groundtruth
7_4.txt
On the Cover: This issue of Matter marks the beginning of our second year of publishing. To celebrate, we arranged a special anniversary issue and invited contributions from a variety of exemplary researchers. We herein invite the materials science community to help us celebrate an exciting rookie season and kick off o...
MAC_Bench/Cell/Story/Matter/3_5.txt
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3_5.txt
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Nature Catalysis
7_4
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Catalysis/7_4.png
A
Dispersion control In their work, L. Robert Baker and colleagues investigate the effects of molecular dispersion of a heterogenized cobalt phthalocyanine on the rate and product selectivity in electrocatalytic CO2 reduction. See Zhu et al. Image: Elad Gross and Hadar Shema, Hebrew University, Jerusalem. Cover design: A...
MAC_Bench/Nature/Story/Nature Catalysis/7_4.txt
groundtruth
7_4.txt
Active sites revealed In their work, the authors present a methodology to map the active sites of nanoparticle catalysts via a combination of atomic electron tomography and first-principles-trained machine learning. This allows them to draw structure–activity relationships and propose a local environment descriptor. Se...
MAC_Bench/Nature/Story/Nature Catalysis/7_6.txt
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7_6.txt
Deactivation into single atoms By controlling the loading of metal nanoparticles in supported catalysts using colloidal nanocrystals, Cargnello and co-workers report a deactivation mechanism in combustion catalysts that occurs by particle decomposition into inactive single atoms rather than by particle growth. This dea...
MAC_Bench/Nature/Story/Nature Catalysis/2_4.txt
vith
2_4.txt
Two eyes on single particles Weckhuysen and co-workers report a set of catalyst sensors that allow for the simultaneous detection of local temperature and surface species on catalyst particles. This provides a powerful method to monitor, characterize and understand catalytic systems. See Hartman et al. Image: Thomas Ha...
MAC_Bench/Nature/Story/Nature Catalysis/2_2.txt
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2_2.txt
test
Journal of the American Chemical Society
2024_26
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Journal of the American Chemical Society/2024_26.png
D
This cover image demonstrates the critical role of the solvent in the ion motion of intrinsically anionic metal–organic framework (MOF)-based quasi-solid-state electrolytes (QSSEs). Using hybrid theoretical and experimental approaches, we have identified solvent-assisted hopping as the dominant pathway for Li+ conducti...
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2022_22.txt
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2022_22.txt
The cover illustrates a rationally designed and synthesized stable, nickel foam-supported, {–210} high-index facet-rich Ni3S2 nanosheet array, dubbed Ni3S2/NF, in action as a highly active, binder-free, bifunctional electrocatalyst for both the hydrogen evolution and the oxygen evolution reactions. See Asefa and co-wor...
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2015_8.txt
vith
2015_8.txt
Light promotes electrons in certain positions of a three-dimensional covalent organic framework into collective excited states. Cover art by Alfy Benny.
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2022_16.txt
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A dataset of high-quality band gaps for perovskite materials is first generated through an advanced electronic structure method and then used to develop a simple but accurate band-gap model through artificial intelligence. This enables a search across large databases, leading to the identification of promising halide p...
MAC_Bench/ACS/Story/Journal of the American Chemical Society/2024_26.txt
groundtruth
2024_26.txt
train
Nature Cell Biology
26_3
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Cell Biology/26_3.png
D
A collage of Nature Cell Biology covers from the past decade.
MAC_Bench/Nature/Story/Nature Cell Biology/11_1.txt
vitg
11_1.txt
Focus on cell death The cover shows 3-colour live imaging in vivo demonstrating a role for ferroptosis-like cell death in triggering macrophage recruitment but delaying the resolution of inflammation during wounding in Drosophila. See Focus for more content. Focus See Davidson et al. Image: Andrew J. Davidson, Universi...
MAC_Bench/Nature/Story/Nature Cell Biology/26_4.txt
vith
26_4.txt
Organelles Isolating intact mitochondria from specific cells shows that the Caenorhabditis elegans germline propagates deleterious mitochondrial genomes. See Ahier et al. Image: Nick Valmas and Steven Zuryn, University of Queensland. Cover Design: Lauren Heslop.
MAC_Bench/Nature/Story/Nature Cell Biology/20_10.txt
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20_10.txt
Heritable amyloids Protein amyloid structures are stably inherited across generations and transmit epigenetic memory in Caenorhabditis elegans. Loss of MSTR, a regulator of the amyloid-like structures, results in a transgenerational feminization phenotype. See Eroglu et al. Image: Matthew Eroglu, SickKids Hospital & Un...
MAC_Bench/Nature/Story/Nature Cell Biology/26_3.txt
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26_3.txt
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Nature Physics
20_5
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Physics/20_5.png
D
Electrons in a fractal Electrons are confined to an artificial Sierpiński triangle. Microscopy measurements show that their wavefunctions become self-similar and their quantum properties inherit a non-integer dimension between 1 and 2. See Morais-Smith et al. Image: Marlou Slot, Utrecht University. Cover Design: David ...
MAC_Bench/Nature/Story/Nature Physics/15_11.txt
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15_11.txt
Two-state cell migration Two-state micropatterns offer a unique platform to study cell migration. An equation of motion is inferred from a large ensemble of trajectories, revealing key differences in the nonlinear dynamics of healthy and cancerous cells. See Broedersz et al. Image: Christoph Hohman, Nanosystems Initiat...
MAC_Bench/Nature/Story/Nature Physics/15_7.txt
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15_7.txt
Charge on the bouncing barrier In our understanding of planetary formation, it is still unclear how millimetre-sized dust grains grow into centimetre-sized aggregates. Microgravity experiments now show that electrical charging of the grains leads to the formation of larger clumps. See Steinpilz et al. Image: Tobias Ste...
MAC_Bench/Nature/Story/Nature Physics/16_11.txt
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16_11.txt
Active holes break multicellular bridges The formation of holes in epithelial tissue is important for development but can also lead to problems, including cancer, if the process does not work smoothly. Jian-Qing Lv and collaborators have tracked the nucleation, coalescence, and eventual formation of a network of holes ...
MAC_Bench/Nature/Story/Nature Physics/20_5.txt
groundtruth
20_5.txt
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Nature Cardiovascular Research
3_7
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Cardiovascular Research/3_7.png
C
Reaching out The cover image of our first issue is a wool artwork entitled ‘Reach’, created by contemporary British artist Sarah Vaci. Reflecting the originality and courage of the artwork, Nature Cardiovascular Research aims to bring together the cardiovascular and blood community, and promote, champion and disseminat...
MAC_Bench/Nature/Story/Nature Cardiovascular Research/1_12.txt
vith
1_12.txt
COVID-19 and atherosclerosis Eberhardt et al. describe how SARS-CoV-2 infects cells within human atherosclerotic lesions, triggering plaque inflammation that contributes to acute cardiovascular complications and long-term risks in patients with COVID-19. See Eberhardt et al. Image: Katie Vicari. Cover design: Bethany V...
MAC_Bench/Nature/Story/Nature Cardiovascular Research/2_3.txt
vitg
2_3.txt
Explaining heart failure Fernandez-Patron et al. propose a unifying framework explaining how diverse risk factors such as hypertension, obesity and diabetes lead to the pathogenesis and progression of heart failure. See Fernandez-Patron et al. Image: Eugenio Hardy, Center for Molecular Immunology, Cuba and Carlos Ferna...
MAC_Bench/Nature/Story/Nature Cardiovascular Research/3_7.txt
groundtruth
3_7.txt
Collateral arteries of the heart The figure adapted from Anbazhakan et al. represents imaging (black and white), hemodynamic forces (magenta), and collateral artery tracing (cyan) in a cohesive collage. The use of a collage symbolizes the interdisciplinary nature of this work. See Anbazhakan et al. and News & Views by ...
MAC_Bench/Nature/Story/Nature Cardiovascular Research/1_5.txt
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1_5.txt
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NATURE BIOTECHNOLOGY
42_10
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE BIOTECHNOLOGY/42_10.png
A
Point-of-care monitoring A miniaturized ultrasonic system can provide full-body monitoring and diagnosis. Lin et al. engineer a soft, wireless ultrasound device to measure deep body signals in moving subjects, offering a hands-free solution for continuous, comprehensive health tracking at the point of care. See Lin et ...
MAC_Bench/Nature/Story/NATURE BIOTECHNOLOGY/42_10.txt
groundtruth
42_10.txt
Focus on wearable sensors Wearable sensors are evolving to provide accurate, continuous and wireless monitoring of our health and disease states. Using designs and materials that interface seamlessly with skin, accessing a range of bodily fluids with minimally invasive systems, and measuring analytes that inform on hum...
MAC_Bench/Nature/Story/NATURE BIOTECHNOLOGY/37_9.txt
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37_9.txt
Nature Biotechnology celebrates its 20-year anniversary. Cover art: Erin Boyle
MAC_Bench/Nature/Story/NATURE BIOTECHNOLOGY/34_10.txt
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Nature Biotechnology celebrates 15 years of publishing the very best of biotech science and business. Cover art: Marina Corral.
MAC_Bench/Nature/Story/NATURE BIOTECHNOLOGY/29_10.txt
ave_0
29_10.txt
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Cell Reports Methods
5_1
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Cell Reports Methods/5_1.png
C
On the cover: Biological samples are often examined at the cellular level in order to draw conclusions or suggest an appropriate medical diagnosis. In this issue, Toth et al. report a method that improves cell classification accuracy using a fisheye-like transformation that incorporates the environment around a cell of...
MAC_Bench/Cell/Story/Cell Reports Methods/2_1.txt
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2_1.txt
On the cover: Welcome to Cell Reports Methods! Our first issue cover features original artwork, from the Cell Press creative team, that conceptualizes the process of scientific discovery as navigating a complex and varied mountain terrain with many possible goals and endpoints. At Cell Reports Methods, we are devoted t...
MAC_Bench/Cell/Story/Cell Reports Methods/1_8.txt
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1_8.txt
On the cover: The cover image illustrates MMoCHi, a supervised machine learning framework for cell-type classification of multimodal, single-cell genomics and spatial profiling data developed by Caron et al. The colored layers and corresponding cell drawings represent different modalities (e.g., morphology, protein, mR...
MAC_Bench/Cell/Story/Cell Reports Methods/5_1.txt
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On the cover: In this issue, Quarles et al. present a method for high-throughput cryosectioning of hundreds of C. elegans in a single block, enabling improved access to antigens for immunostaining. As shown in the cover image, they use this method to establish C. elegans as a multicellular model for studying the functi...
MAC_Bench/Cell/Story/Cell Reports Methods/4_3.txt
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4_3.txt
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Organometallics
2025_2
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/Organometallics/2025_2.png
D
What is the application? Consider how organometallic expertise can be extended to determine and realize new translational research opportunities. The diverse applications of organometallic chemistry featured in this Special Issue continue to inspire creative directions and novel approaches within the discipline.
MAC_Bench/ACS/Story/Organometallics/2024_5.txt
ave_1
2024_5.txt
Sustainable Organometallic Chemistry is important to develop new processes that are less dependent on finite natural resources. This Special Issue focuses on various approaches to replace nonsustainable chemical reagents with more sustainable alternatives. The cover art depicts some of the ingredients that are needed t...
MAC_Bench/ACS/Story/Organometallics/2022_11.txt
vith
2022_11.txt
The future is shining bright for organometallics. This special issue shines light on photo-active organometallic complexes and their applications as photoredox catalysts.
MAC_Bench/ACS/Story/Organometallics/2024_9.txt
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This cover art is a concise and retro-artistic representation of our research, a synthesis using high-pressure nitrogen. In this work, we have succeeded for the first time in analyzing the single crystal structure of a dinitrogen complex, [Cr(PCy3)2(CO)3(N2)], which has been known for a long time. We also revealed the ...
MAC_Bench/ACS/Story/Organometallics/2025_2.txt
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2025_2.txt
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NATURE REVIEWS MICROBIOLOGY
22_2
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE REVIEWS MICROBIOLOGY/22_2.png
C
Harnessing the microbiome for sustainable crop production, inspired by the Review on p9 Cover design: Amie Fernandez
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/23_2.txt
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23_2.txt
The indoor microbiome, inspired by the Review on p742. Cover design: Amie Fernandez
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/22_1.txt
vitg
22_1.txt
Feeding the microbiome, inspired by the Review on p671. Cover design: Amie Fernandez
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/22_2.txt
groundtruth
22_2.txt
Microbial food spoilage, inspired by the Review on p528. Cover design: Amie Fernandez
MAC_Bench/Nature/Story/NATURE REVIEWS MICROBIOLOGY/22_4.txt
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22_4.txt
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Trends in Chemistry
7_1
Which of the following options best describe the cover image?
MAC_Bench/Cell/Cover/Trends in Chemistry/7_1.png
D
In this special issue of Trends in Chemistry, we wrap up our inaugural content by continuing to address big questions in chemistry. We introduce 14 new articles outlining key topics in chemistry including: lithium-metal batteries; electrochemical water splitting; light hydrocarbon separations; glycosidic bond hydroxyla...
MAC_Bench/Cell/Story/Trends in Chemistry/1_9.txt
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1_9.txt
Over the past decade, machine learning algorithms (MLAs) have been employed extensively to speed up the discovery, synthesis, and optimization of molecules and materials. This Special Issue highlights key areas where machine learning has made, and will continue to make, a positive impact on molecular and materials rese...
MAC_Bench/Cell/Story/Trends in Chemistry/3_12.txt
vith
3_12.txt
In this special issue of Trends in Chemistry, we highlight the design and emerging catalytic applications of transition metals and their complexes in organic and organometallic chemistry, including: C-C bond formation, C-H functionalization, branch-selective olefin hydroarylation, carbon-dioxide methanation, and chemo-...
MAC_Bench/Cell/Story/Trends in Chemistry/1_5.txt
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Polyoxovanadates (POVs) are a versatile class of metal-oxido clusters with excellent solution, redox and thermal stability, and are particularly noted for binding to various peptide and protein targets with various therapeutic outcomes. In their Forum article in this issue, Merlino and co-workers discuss recent data on...
MAC_Bench/Cell/Story/Trends in Chemistry/7_1.txt
groundtruth
7_1.txt
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NATURE REVIEWS DRUG DISCOVERY
23_7
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE REVIEWS DRUG DISCOVERY/23_7.png
A
A framework for RNA-based medicines, inspired by the Review on p421. Cover design: S. Harris
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/23_7.txt
groundtruth
23_7.txt
Evolution of therapeutic strategies for COVID-19, inspired by the Review on p449. Cover design: S. Harris
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/22_7.txt
vitg
22_7.txt
Targeting hypoxia-inducible factors, inspired by the Review on p175. Cover design: S. Harris
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/23_10.txt
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23_10.txt
Delivering genome editors, inspired by the Review on p875. Cover design: S. Harris
MAC_Bench/Nature/Story/NATURE REVIEWS DRUG DISCOVERY/22_2.txt
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22_2.txt
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Nature Reviews Nephrology
20_7
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/Nature Reviews Nephrology/20_7.png
A
Kidney-targeted nanomedicines, inspired by the Review on p354. Cover design: Lara Crow
MAC_Bench/Nature/Story/Nature Reviews Nephrology/20_7.txt
groundtruth
20_7.txt
Unlocking tissue-specific T cell responses, inspired by the Review on p209. Cover design: Lara Crow
MAC_Bench/Nature/Story/Nature Reviews Nephrology/18_9.txt
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18_9.txt
Endothelial cell metabolism, inspired by the Review on p441. Cover design: Lara Crow
MAC_Bench/Nature/Story/Nature Reviews Nephrology/17_6.txt
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17_6.txt
COVER: The intracellular complement system, inspired by the Review on p426. Cover design: Lara Crow
MAC_Bench/Nature/Story/Nature Reviews Nephrology/19_6.txt
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19_6.txt
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ACS Chemical Neuroscience
2024_12
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS Chemical Neuroscience/2024_12.png
A
ᴅ-glucose ([18F]FDG) PET imaging. [18F]FDG PET offers a quantitative and translational neuroimaging method to explore the CNS effects of candidate drugs for smoking cessation therapy.
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2024_12.txt
groundtruth
2024_12.txt
10.1021/acschemneuro.0c00004
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2020_21.txt
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The mechanisms accounting for the formation of pores by amyloid peptides are revealed by unbiased all-atom simulations. Peptides adsorb, aggregate into β-sheets, and form pores spontaneously at the surface of lipid bilayers. Four peptides differing in the distribution of polar and nonpolar residues along the sequence a...
MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2024_7.txt
vith
2024_7.txt
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MAC_Bench/ACS/Story/ACS Chemical Neuroscience/2010_12.txt
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2010_12.txt
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ACS ES&T Water
2025_2
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS ES&T Water/2025_2.png
B
Read the recent Collection on Wastewater-Based Epidemiology
MAC_Bench/ACS/Story/ACS ES&T Water/2024_6.txt
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2024_6.txt
This Special Issue entitled “3D Printing Technologies for Environmental and Water Applications” highlights the diverse applications of 3D printing technologies in environmental sectors. Owing to their exceptional efficiency, flexible structures, and ease of recovery, 3D-printed catalysts hold significant potential for ...
MAC_Bench/ACS/Story/ACS ES&T Water/2025_2.txt
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2025_2.txt
Welcome to the inaugural issue of ACS ES&T Water, a multidisciplinary journal dedicated to all aspects of water research and policy.  Research investigating water quality, chemistry, treatment, protection, and sustainable use/reuse and supply is in scope.  The journal considers freshwater and marine environments, and i...
MAC_Bench/ACS/Story/ACS ES&T Water/2021_12.txt
vith
2021_12.txt
Predicting daily discharge of wastewater treatment plants (WWTPs) using a machine learning model supported by meteorological and population migration big data in the Guangdong-Hong Kong-Macao Greater Bay Area of China.
MAC_Bench/ACS/Story/ACS ES&T Water/2023_8.txt
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2023_8.txt
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NATURE MEDICINE
30_1
Which of the following options best describe the cover image?
MAC_Bench/Nature/Cover/NATURE MEDICINE/30_1.png
A
Human Cell Atlas In this issue, multiple studies from the Human Cell Atlas report findings from human single-cell and spatial genomics datasets of vascular cells, healthy female breast tissues, placentas, and lung tissues from people with fatal COVID-19. The cover depicts these data projected onto a multifaceted lanter...
MAC_Bench/Nature/Story/NATURE MEDICINE/30_1.txt
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30_1.txt
30th anniversary issue: the Future of Medicine As Nature Medicine turns 30 years old, we will, throughout 2025, be looking at the future of medicine. In this first issue, we turn our attention to next-generation drug discovery. Image and cover design: Alex Whitworth
MAC_Bench/Nature/Story/NATURE MEDICINE/31_1.txt
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31_1.txt
In 2004, Nature Medicine enters its tenth year of publication, continuing our mission to serve the biomedical research community as the venue for top-flight primary research articles, news and perspectives. The cover image commemorates our anniversary year with a collage of covers spanning our publication history. (Gra...
MAC_Bench/Nature/Story/NATURE MEDICINE/10_12.txt
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Medicine in the digital age As Nature Medicine celebrates its 25th anniversary, we bring our readers a special Focus on Digital Medicine that highlights the new technologies transforming medicine and healthcare, as well as the related regulatory challenges ahead. See Focus Image credit: Peter Crowther. Cover design: Er...
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25_12.txt
train
ACS ES&T Water
2024_3
Which of the following options best describe the cover image?
MAC_Bench/ACS/Cover/ACS ES&T Water/2024_3.png
C
The editors at ACS ES&T Water are pleased to announce the winners of the 2022 ACS ES&T Water Best Paper Award, showcasing some of the most outstanding papers published in 2022 issues.  The front cover lists the topics covered by the winners of the award.  Please view the Editorial for full information on the winning pa...
MAC_Bench/ACS/Story/ACS ES&T Water/2023_1.txt
vith
2023_1.txt
Welcome to the inaugural issue of ACS ES&T Water, a multidisciplinary journal dedicated to all aspects of water research and policy.  Research investigating water quality, chemistry, treatment, protection, and sustainable use/reuse and supply is in scope.  The journal considers freshwater and marine environments, and i...
MAC_Bench/ACS/Story/ACS ES&T Water/2021_12.txt
clip
2021_12.txt
The superior sensitivity and specificity of qPCR allow for the quantification of algal genera and the discovery of algae response to reservoir characteristics that traditional microscopy methods could not easily detect.
MAC_Bench/ACS/Story/ACS ES&T Water/2024_3.txt
groundtruth
2024_3.txt
This special issue showcases the latest advances in membrane technologies to remove and recover valuable resources from water streams. The artwork by Yang et al.
MAC_Bench/ACS/Story/ACS ES&T Water/2023_6.txt
ave_2
2023_6.txt
train