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9,124,140 | 2022-03-22T16:26:07Z | CCBY | https://academic.oup.com/nar/article-pdf/43/D1/D873/7330380/gku843.pdf | GOLD | 1ef366e034d08317e9305bb390aed643459baba4 | null | null | null | journals/nar/CraigSTWWSJSMAM15 | 10.1093/nar/gku843 | 2169010206 | 25232097 | 4384002 |
The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource
2015
Thomas Craig
Integrative Genomics of Ageing Group
Institute of Integrative Biology
University of Liverpool
LiverpoolUK
Chris Smelick
University of North Carolina at Chapel Hill
NCUSA
Robi Tacutu
Integrative Ge... | [
"Multiple studies characterizing the human ageing phenotype have been conducted for decades. However, there is no centralized resource in which data on multiple age-related changes are collated. Currently, researchers must consult several sources, including primary publications, in order to obtain age-related data ... | [
"Thomas Craig \nIntegrative Genomics of Ageing Group\nInstitute of Integrative Biology\nUniversity of Liverpool\nLiverpoolUK\n",
"Chris Smelick \nUniversity of North Carolina at Chapel Hill\nNCUSA\n",
"Robi Tacutu \nIntegrative Genomics of Ageing Group\nInstitute of Integrative Biology\nUniversity of Liverpool\... | [
"Integrative Genomics of Ageing Group\nInstitute of Integrative Biology\nUniversity of Liverpool\nLiverpoolUK",
"University of North Carolina at Chapel Hill\nNCUSA",
"Integrative Genomics of Ageing Group\nInstitute of Integrative Biology\nUniversity of Liverpool\nLiverpoolUK",
"Integrative Genomics of Ageing ... | [
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"Messages from mortality: the evolution of death rates in the old. L Partridge, M Mangel, Trends Ecol. Evol. 14Partridge,L. and Mangel,M. (1999) Messages from mortality: the evolution of death rates in the old. Trends Ecol. Evol., 14, 438-442.",
"B Arking, Biology of Aging: Observations and Principles. USAOxford ... | [
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"Messages from mortality: the evolution of death rates in the old",
"Systems biology of ageing and longevity",
"Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies",
"Meta-analysis of age-related gene expression profiles identifies common signatures of ... | [
"USA",
"Trends Ecol. Evol",
"Biology of Aging: Observations and Principles",
"Physiological Basis of Aging and Geriatrics",
"Philos. Trans. R. Soc. Lond. B. Biol. Sci",
"Curr. Pharm. Des",
"Bioinformatics",
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"\nFigure 1 .\n1The DAA anatomical model. Moving the mouse over a given organ reveals the number of age-related changes in the DAA, along with a breakdown of the number of each specific type of change. Colours indicate the number of changes for each change type (orange: physiological, red: pathological, blue: molec... | [
"The DAA anatomical model. Moving the mouse over a given organ reveals the number of age-related changes in the DAA, along with a breakdown of the number of each specific type of change. Colours indicate the number of changes for each change type (orange: physiological, red: pathological, blue: molecular, green: ps... | [
"(Figure 1",
"Figure 2",
"(Figure 3",
"Figure 2",
"(Figure 4"
] | [] | [
"Ageing can be defined as a progressive functional decline, or a gradual deterioration of physiological function with age, often including a decrease in fecundity (1). Human ageing is characterized by multiple changes at different levels of bi-ological organization (2,3). It is still not clear which (if any) molecu... | [] | [
"INTRODUCTION",
"DATA SELECTION AND CURATION",
"AVAILABILITY",
"CONCLUSION",
"Figure 1 .",
"Figure 3 .",
"Figure 4 .",
"Table 1 ."
] | [
"Type of change \nDescription \n"
] | [
"Table 1"
] | [
"The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource",
"The Digital Ageing Atlas: integrating the diversity of age-related changes into a unified resource"
] | [
"Nucleic Acids Research"
] |
231,756,643 | 2022-01-15T10:33:33Z | CCBY | https://www.mdpi.com/1422-0067/22/3/1073/pdf | GOLD | 8e7ed1b584fe0542b030798e61721097dbea002d | null | null | null | null | 10.3390/ijms22031073 | null | 33499037 | 7865694 | "\nMachine Learning Analysis of Longevity-Associated Gene Expression Landscapes in Mammals\n2021\n\n(...TRUNCATED) | ["Citation: Kulaga, A.Y.; Ursu, E.; Toren, D.; Tyshchenko, V.; Guinea, R.; Pushkova, M.; Fraifeld, V(...TRUNCATED) | ["Anton Y Kulaga \nSystems Biology of Aging Group\nInstitute of Biochemistry of the Romanian Academy(...TRUNCATED) | ["Systems Biology of Aging Group\nInstitute of Biochemistry of the Romanian Academy\n060031Bucharest(...TRUNCATED) | [
"Anton",
"Y",
"Eugen",
"Dmitri",
"Vladyslava",
"Rodrigo",
"Malvina",
"Vadim",
"E",
"Robi"
] | [
"Kulaga",
"Ursu",
"Toren",
"Tyshchenko",
"Guinea",
"Pushkova",
"Fraifeld",
"Tacutu"
] | ["A Budovsky, ","A Abramovich, ","R Cohen, ","V Chalifa-Caspi, ","V Fraifeld, ","H Yanai, ","A Budov(...TRUNCATED) | ["A","A","R","V","V","H","A","T","R","V","E","R","D","E","A","D","T","E","G","D","J","L","Y","A","W"(...TRUNCATED) | ["Budovsky","Abramovich","Cohen","Chalifa-Caspi","Fraifeld","Yanai","Budovsky","Barzilay","Tacutu","(...TRUNCATED) | ["Longevity network: Construction and implications. A Budovsky, A Abramovich, R Cohen, V Chalifa-Cas(...TRUNCATED) | ["[1]","[2]","[3]","[4]","[5,","6]","[3]","[7]","[8]","[9]","[10]","[15]","[16]","[17]","38","3)","3(...TRUNCATED) | ["Longevity network: Construction and implications","Wide-scale comparative analysis of longevity ge(...TRUNCATED) | ["Mech. Age. Dev","Aging Cell","Nucl. Acids Res","Growth hormone-releasing hormone disruption extend(...TRUNCATED) | ["\nFigure 1 .\n1Schematic representation of the analysis workflow used in this study.","\nFigure 1 (...TRUNCATED) | ["Schematic representation of the analysis workflow used in this study.","Schematic representation o(...TRUNCATED) | ["Figure 1","(Figure 2a","(Figure 2a","(Figure 2b","(Figure 2b","(Figure 2b","Figure S1","Figure S1a(...TRUNCATED) | [] | ["Numerous studies have showed that the average lifespan, and in some cases even maximum lifespan (M(...TRUNCATED) | [] | ["Introduction","Results and Discussion","Data Collection and Processing of Gene Expression across M(...TRUNCATED) | ["Organ \nNumber of \nSamples \n\nRMSE \n(Years) \nR 2 \nMAE \nSignificant Genes for the Linear Regr(...TRUNCATED) | ["Supplementary Table S2","Supplementary Table S2","Supplementary Table S2","Supplementary Table S3(...TRUNCATED) | ["Machine Learning Analysis of Longevity-Associated Gene Expression Landscapes in Mammals","Machine (...TRUNCATED) | [
"International Journal of Molecular Sciences Article Int. J. Mol. Sci"
] |
21,237,600 | 2022-08-31T06:02:33Z | CCBY | https://academic.oup.com/nar/article-pdf/44/D1/D1262/9482914/gkv1187.pdf | GOLD | 9a929618736bf8a69f64ef9087381ee99394fe74 | null | null | null | journals/nar/TorenBTLMF16 | 10.1093/nar/gkv1187 | 2174493298 | 26590258 | 4702847 | "\nMitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal(...TRUNCATED) | ["Mitochondria are the only organelles in the animal cells that have their own genome. Due to a key (...TRUNCATED) | ["Dmitri Toren \nThe Shraga Segal Department of Microbiology, Immunology and Genetics\nCenter for Mu(...TRUNCATED) | ["The Shraga Segal Department of Microbiology, Immunology and Genetics\nCenter for Multidisciplinary(...TRUNCATED) | [
"Dmitri",
"Thomer",
"Robi",
"Gilad",
"Khachik",
"K",
"Vadim",
"E"
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"Toren",
"Barzilay",
"Tacutu",
"Lehmann",
"Muradian",
"Fraifeld"
] | ["D C Wallace, ","C Lopez-Otin, ","M A Blasco, ","L Partridge, ","M Serrano, ","G Kroemer, ","N Apos(...TRUNCATED) | ["D","C","C","M","A","L","M","G","N","A","J","V","G","E","K","K","V","E","F","C","D","E","A","F","P"(...TRUNCATED) | ["Wallace","Lopez-Otin","Blasco","Partridge","Serrano","Kroemer","Apostolova","Blas-Garcia","Esplugu(...TRUNCATED) | ["A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evo(...TRUNCATED) | ["(1)","(2)","(3)","(4)","(5)","(6)","(7,","8)","(10)","(5,","11,","12)","(4,","6,","(13)","(14)","((...TRUNCATED) | ["A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evo(...TRUNCATED) | ["Annu. Rev. Genet","Cell","Curr. Pharm. Des","Rejuvenation Res","Exp. Gerontol","Prog. Mol. Biol. T(...TRUNCATED) | ["\nCFigure 1 .\n1The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acid(...TRUNCATED) | ["The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. This(...TRUNCATED) | [
"(Figures 1 and 2)"
] | [] | ["Mitochondria are the only organelles in the animal cells that have their own genome. The stability(...TRUNCATED) | [] | ["INTRODUCTION","DATABASE CONTENT AND INTERFACE","DATA SOURCES AND DATA CURATION","DATA CALCULATION"(...TRUNCATED) | [
"Taxa (scientific name) \n"
] | [
"Table 1"
] | ["MitoAge: a database for comparative analysis of mitochondrial DNA, with a special focus on animal (...TRUNCATED) | [
"Nucleic Acids Research"
] |
212,751,312 | 2022-08-27T11:09:50Z | CCBY | https://www.mdpi.com/2073-4425/11/3/286/pdf | GOLD | b34684ec3cbc3c9e40621ece2d4af67510153c76 | null | null | null | null | 10.3390/genes11030286 | 3009570400 | 32182725 | 7140858 | "\nLRRpredictor-A New LRR Motif Detection Method for Irregular Motifs of Plant NLR Proteins Using an(...TRUNCATED) | ["Leucine-rich-repeats (LRRs) belong to an archaic procaryal protein architecture that is widely inv(...TRUNCATED) | ["Eliza C Martin eliza.martin@biochim.roe.c.m. \nDepartment of Bioinformatics and Structural Biochem(...TRUNCATED) | ["Department of Bioinformatics and Structural Biochemistry\nInstitute of Biochemistry of the Romania(...TRUNCATED) | [
"Eliza",
"C",
"C",
"A",
"Laurentiu",
"Laurentiu",
"G",
"Vlad",
"Robi",
"Aska",
"Andrei-Jose"
] | [
"Martin",
"Octavina",
"Sukarta",
"Spiridon",
"Grigore",
"Constantinescu",
"Tacutu",
"Goverse",
"Petrescu"
] | ["P Enkhbayar, ","M Kamiya, ","M Osaki, ","T Matsumoto, ","N Matsushima, ","R F Warren, ","A Henk, "(...TRUNCATED) | ["P","M","M","T","N","R","F","A","P","E","R","W","Y","S","A","G","T","H","P","B","F","P","Y","H","S"(...TRUNCATED) | ["Enkhbayar","Kamiya","Osaki","Matsumoto","Matsushima","Warren","Henk","Mowery","Holub","Innes","Jia(...TRUNCATED) | ["Structural Principles of Leucine-Rich Repeat (LRR) Proteins. P Enkhbayar, M Kamiya, M Osaki, T Mat(...TRUNCATED) | ["[1]","[2]","[3]","[4]","[21,","22]","[10,","25]","[26]","[27]","[28]","[29]","[30]","[31]","[32]",(...TRUNCATED) | ["Structural Principles of Leucine-Rich Repeat (LRR) Proteins","A mutation within the leucine-rich r(...TRUNCATED) | ["Proteins Struct. Funct. Bioinform","Plant Cell","EMBO J","J. Allergy Clin. Immunol","Neuron","Neur(...TRUNCATED) | ["\nFigure 1 .\n1Available leucine-rich-repeat (LRR) domains in structural data. (a) LRR structural (...TRUNCATED) | ["Available leucine-rich-repeat (LRR) domains in structural data. (a) LRR structural dataset constru(...TRUNCATED) | ["Figure A1a","Figure 1","Figure 1e","Figure 1c","Figure 2d","Figure 1a","Figure 1b)","Figure A1d","(...TRUNCATED) | [
"d(i, j) = s(i, i) + s( j, j) − 2·s(i, j)(1)",
"D a,b = l i=0 d(a i , b i ),(2)"
] | ["The leucine-rich-repeat (LRR) domains are present in all of the tree of life branches. As they are(...TRUNCATED) | [] | ["Introduction","Materials and Methods","Assembly and Analysis of the LRR Structural Dataset","Train(...TRUNCATED) | ["Full NonLRR Proteins \nLRR Proteins \n\n","Dataset \nClassifier \n\nIn-Sample \nOut-Of Sample \n\n(...TRUNCATED) | [
"Table 1",
"(Table 1",
"Table A1",
"(Table A1)",
"(Table A1)",
"Table A1"
] | ["LRRpredictor-A New LRR Motif Detection Method for Irregular Motifs of Plant NLR Proteins Using an (...TRUNCATED) | [] |
237,479,797 | 2022-01-10T05:35:55Z | CCBY | https://doi.org/10.18632/aging.203518 | GOLD | 1c8fde34e660e157d40048091edfdda3d5b367eb | null | null | null | null | 10.18632/aging.203518 | null | 34506301 | 8457566 | "\nKnock-down of odr-3 and ife-2 additively extends lifespan and healthspan in C. elegans\nPublished(...TRUNCATED) | ["Genetic manipulations can ameliorate the aging process and extend the lifespan of model organisms.(...TRUNCATED) | ["Ioan Valentin Matei \nSystems Biology of Aging Group\nInstitute of Biochemistry of the Romanian Ac(...TRUNCATED) | ["Systems Biology of Aging Group\nInstitute of Biochemistry of the Romanian Academy\nBucharestRomani(...TRUNCATED) | [
"Ioan",
"Valentin",
"Vimbai",
"Charity",
"Gabriela",
"Dmitri",
"Simona",
"Robi"
] | [
"Matei",
"Netsai",
"Samukange",
"Bunu",
"Toren",
"Ghenea",
"Tacutu"
] | ["J M Phillip, ","I Aifuwa, ","J Walston, ","D Wirtz, ","M Lemoine, ","R N Butler, ","R A Miller, ",(...TRUNCATED) | ["J","M","I","J","D","M","R","N","R","A","D","B","A","T","F","C","J","M","A","L","T","G","M","S","J"(...TRUNCATED) | ["Phillip","Aifuwa","Walston","Wirtz","Lemoine","Butler","Miller","Perry","Carnes","Williams","Casse(...TRUNCATED) | ["The Mechanobiology of Aging. J M Phillip, I Aifuwa, J Walston, D Wirtz, 10.1146/annurev-bioeng-071(...TRUNCATED) | ["[1,","2]","[3]","[4]","[5]","[6]","[7]","[8]","[9]","[9]","[10]","[13]","[14]","[15]","[9]","[16,"(...TRUNCATED) | ["The Mechanobiology of Aging","Defining aging","New model of health promotion and disease preventio(...TRUNCATED) | ["Annu Rev Biomed Eng","Biol Philos","BMJ","J Gerontol A Biol Sci Med Sci","Transl Res","Nature","Na(...TRUNCATED) | ["\nFigure 1 .\n1Kaplan-Meier survival curves depicting the effects of combined genetic intervention(...TRUNCATED) | ["Kaplan-Meier survival curves depicting the effects of combined genetic interventions on odr-3, ife(...TRUNCATED) | ["Figure 1A","Figure 1B","Figure 1A","Figure 1B","Figure 1A-1C)","Figure 1D","Figure 1C","Figure 1D"(...TRUNCATED) | [] | ["The aging process might be defined by the progressive loss of viability and by an increase in frag(...TRUNCATED) | [] | ["INTRODUCTION","RESULTS","RNA interference of ife-2 but not cku-70 increases lifespan of the long-l(...TRUNCATED) | ["Strain RNAi* Mean lifespan days ± SD \nEffect vs control \np-value Strain RNAi* \nMean lifespan d(...TRUNCATED) | ["Table 1)","Supplementary Table 1","(Table 1)","Table 1","Table 1 and Supplementary Table 1","(Tab(...TRUNCATED) | ["Knock-down of odr-3 and ife-2 additively extends lifespan and healthspan in C. elegans","Knock-dow(...TRUNCATED) | [] |
708,686 | 2022-07-14T06:45:02Z | CCBY | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0048282&type=printable | GOLD | 76287e8c5b1b81b09d7fbae1b00b4152d1943271 | null | null | null | null | 10.1371/journal.pone.0048282 | 2060694610 | 23144747 | 3483217 | "\nPrediction of C. elegans Longevity Genes by Human and Worm Longevity Networks\nPublished October (...TRUNCATED) | ["Intricate and interconnected pathways modulate longevity, but screens to identify the components o(...TRUNCATED) | ["Robi Tacutu \nThe Shraga Segal Department of Microbiology, Immunology and Genetics\nCenter for Mul(...TRUNCATED) | ["The Shraga Segal Department of Microbiology, Immunology and Genetics\nCenter for Multidisciplinary(...TRUNCATED) | [
"Robi",
"David",
"E",
"Arie",
"Joã",
"Pedro",
"Gary",
"Vadim",
"E",
"Sean",
"P"
] | [
"Tacutu",
"Shore",
"Budovsky",
"De Magalhã Es",
"Ruvkun",
"Fraifeld",
"Curran"
] | ["S S Lee, ","M R Klass, ","C Kenyon, ","J Chang, ","E Gensch, ","A Rudner, ","R Tabtiang, ","E L Gr(...TRUNCATED) | ["S","S","M","R","C","J","E","A","R","E","L","A","M","A","L","A","C","B","Y","M","W","I","S","G","T"(...TRUNCATED) | ["Lee","Klass","Kenyon","Chang","Gensch","Rudner","Tabtiang","Greer","Brunet","Hansen","Hsu","Dillin(...TRUNCATED) | ["Whole genome RNAi screens for increased longevity: important new insights but not the whole story.(...TRUNCATED) | ["[1]","[2]","[3,","4]","[5,","6]","[1]","[7]","[8,","9]","[10,","11,","12,","13,","14,","15]","[7,"(...TRUNCATED) | ["Whole genome RNAi screens for increased longevity: important new insights but not the whole story"(...TRUNCATED) | ["Exp Gerontol","Mech Ageing Dev","Nature","Aging Cell","PLoS Genet","Genes Dev","PLoS Genet","Journ(...TRUNCATED) | ["\nFigure 2 .\n2Disruption of translation extends longevity in C. elegans. The gene inactivations f(...TRUNCATED) | ["Disruption of translation extends longevity in C. elegans. The gene inactivations found to extend (...TRUNCATED) | ["Figure 1","(Figure 1","Figure 3","(Tables 1 and 2","(Table 1, Figure 2","Figure 2","Figure 3","Fig(...TRUNCATED) | [] | ["Numerous pathways contribute to longevity, but the identification of their components has not been(...TRUNCATED) | [] | ["Introduction","Materials and Methods","Data Sources","Network Construction","Prediction of New Wor(...TRUNCATED) | ["Gene \nCommon name \nLifespan (%D mean) a \nLifespan (%D max) a \nFunction \n\nT23D8.3 \nT23D8.3 \(...TRUNCATED) | ["Table 3","(Tables S2 and S3","(Table S1","(Table S2","(Table S3)","(Table S1","(Table S2","(Table(...TRUNCATED) | ["Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks","Prediction of C. e(...TRUNCATED) | [] |
20,067,865 | 2022-03-13T19:59:13Z | CCBY | https://doi.org/10.1111/acel.12659 | GOLD | 93d687e8ff81b1ab32374d3bca6c7f4ec9e9c429 | null | null | null | null | 10.1111/acel.12659 | 2745510249 | 28836369 | 5676071 | "\nWide-scale comparative analysis of longevity genes and interventions\n\n\nHagai Yanai \nThe Shrag(...TRUNCATED) | ["Hundreds of genes, when manipulated, affect the lifespan of model organisms (yeast, worm, fruit fl(...TRUNCATED) | ["Hagai Yanai \nThe Shraga Segal Department of Microbiology, Immunology and Genetics\nCenter for Mul(...TRUNCATED) | ["The Shraga Segal Department of Microbiology, Immunology and Genetics\nCenter for Multidisciplinary(...TRUNCATED) | [
"Hagai",
"Arie",
"Thomer",
"Robi",
"Vadim",
"E"
] | [
"Yanai",
"Budovsky",
"Barzilay",
"Tacutu",
"Fraifeld"
] | ["M V Blagosklonny, ","A Budovsky, ","A Abramovich, ","R Cohen, ","V Chalifa-Caspi, ","V Fraifeld, "(...TRUNCATED) | ["M","V","A","A","R","V","V","A","R","H","A","M","V","A","B","J","R","L","S","D","C","A","N","O&apos(...TRUNCATED) | ["Blagosklonny","Budovsky","Abramovich","Cohen","Chalifa-Caspi","Fraifeld","Budovsky","Tacutu","Yana(...TRUNCATED) | ["M(o)TOR of aging: MTOR as a universal molecular hypothalamus. M V Blagosklonny, Aging (Albany NY).(...TRUNCATED) | ["(Vijg & Suh, 2005;","Kenyon, 2010)","(Tacutu et al., 2013)","(Budovsky et al., 2007;","Tacutu et a(...TRUNCATED) | ["M(o)TOR of aging: MTOR as a universal molecular hypothalamus","Longevity network: construction and(...TRUNCATED) | ["Aging (Albany NY)","Mech. Ageing Dev","Mech. Ageing Dev","Nucleic Acids Res","PLoS ONE","PLoS Gene(...TRUNCATED) | ["\n\n(a) Saccharomyces cerevisiae, n = 6590 for control, 824 for all LAGs, and 277 for LSE-LAGs. (b(...TRUNCATED) | ["(a) Saccharomyces cerevisiae, n = 6590 for control, 824 for all LAGs, and 277 for LSE-LAGs. (b) C.(...TRUNCATED) | ["Fig. 1","(Fig. 2)","(Fig. 1)","Fig. 2a)","(Fig. 1b)","(Fig. 1b)","Fig. 1","Fig. S1","(Fig. S2","Fi(...TRUNCATED) | [] | ["The role of genetic factors in determination of longevity and aging patterns is an intensively stu(...TRUNCATED) | [] | ["Introduction","Results","Orthology of longevity-associated genes","'Public' and 'private' LAG cate(...TRUNCATED) | ["Public/Private \nSaccharomyces cerevisiae \nCaenorhabditis elegans \nDrosophila melanogaster \nMus(...TRUNCATED) | ["(Table S1)","Table S1","(Table S2","Table S1","Table S3","Table 1","Table S4","(Table 1","Table S4(...TRUNCATED) | ["Wide-scale comparative analysis of longevity genes and interventions","Wide-scale comparative anal(...TRUNCATED) | [] |
52,829,264 | 2022-03-01T11:08:03Z | CCBY | https://doi.org/10.1093/nar/gkx1042 | GOLD | 656ed0833088fbdfccecd4808caebe1925fdadc9 | null | null | null | journals/nar/TacutuTJBBCDLTW18 | 10.1093/nar/gkx1042 | 2767517408 | 29121237 | 5753192 | "\nHuman Ageing Genomic Resources: new and updated databases\n2018\n\nRobi Tacutu \nIntegrative Geno(...TRUNCATED) | ["In spite of a growing body of research and data, human ageing remains a poorly understood process.(...TRUNCATED) | ["Robi Tacutu \nIntegrative Genomics of Ageing Group\nInstitute of Ageing and Chronic Disease\nUnive(...TRUNCATED) | ["Integrative Genomics of Ageing Group\nInstitute of Ageing and Chronic Disease\nUniversity of Liver(...TRUNCATED) | ["Robi","Daniel","Emily","Arie","Diogo","Thomas","Eugene","Gilad","Dmitri","Jingwei","Vadim","E","Jo(...TRUNCATED) | ["Tacutu","Thornton","Johnson","Budovsky","Barardo","Craig","Diana","Lehmann","Toren","Wang","Fraife(...TRUNCATED) | ["C Lopez-Otin, ","M A Blasco, ","L Partridge, ","M Serrano, ","G Kroemer, ","J P De Magalhaes, ","J(...TRUNCATED) | ["C","M","A","L","M","G","J","P","J","O","R","T","A","D","G","D","J","V","E","J","P","A","G","J","Y"(...TRUNCATED) | ["Lopez-Otin","Blasco","Partridge","Serrano","Kroemer","De Magalhaes","Costa","Toussaint","Tacutu","(...TRUNCATED) | ["The hallmarks of aging. C Lopez-Otin, M A Blasco, L Partridge, M Serrano, G Kroemer, Cell. 153Lope(...TRUNCATED) | ["(1)","(2)","(2)","(3)","(4)","(5)","(6)","(8)","(9)","(4)","(11)","(12)","(13)","(14)","(15)","(16(...TRUNCATED) | ["The hallmarks of aging","HAGR: the Human Ageing Genomic Resources","Human Ageing Genomic Resources(...TRUNCATED) | ["Cell","Nucleic Acids Res","Nucleic Acids Res","Aging Cell","Mech. Ageing Dev","Nature","Nat. Rev. (...TRUNCATED) | ["\nFigure 1 .\n1Patterns of ageing research for different human genes over time. The proportion of (...TRUNCATED) | ["Patterns of ageing research for different human genes over time. The proportion of publications th(...TRUNCATED) | [
"(Figure 1",
"(Figure 1",
"(Figure 2A)",
"Figure 2B"
] | [] | ["Ageing is a complex biological process that, despite decades of research, is not yet well understo(...TRUNCATED) | [] | ["INTRODUCTION","DATABASE CONTENT","GenAge--the ageing gene database","AnAge--the database of animal(...TRUNCATED) | [
"Database \nSpecies \n"
] | [
"(Table 1)",
"(Table 1)"
] | ["Human Ageing Genomic Resources: new and updated databases","Human Ageing Genomic Resources: new an(...TRUNCATED) | [
"Nucleic Acids Research"
] |
238,230,569 | 2023-02-22T16:52:05Z | CCBY | https://www.nature.com/articles/s41598-021-98674-6.pdf | GOLD | 162da7fa23c3a96dfd25c59a41eeb72d79adf8b7 | null | null | null | null | 10.1038/s41598-021-98674-6 | null | 34588506 | 8481473 | "\nSystems biology analysis of lung fibrosis-related genes in the bleomycin mouse model\n0123456789.(...TRUNCATED) | ["Tissue fibrosis is a major driver of pathology in aging and is involved in numerous age-related di(...TRUNCATED) | ["Dmitri Toren \nSystems Biology of Aging Group\nInstitute of Biochemistry of the Romanian Academy\n(...TRUNCATED) | ["Systems Biology of Aging Group\nInstitute of Biochemistry of the Romanian Academy\n060031Bucharest(...TRUNCATED) | [
"Dmitri",
"Hagai",
"Reem",
"Gabriela",
"Eugen",
"Rolf",
"Robi",
"E"
] | [
"Toren",
"Yanai",
"Abu Taha",
"Bunu",
"Ursu",
"Ziesche",
"Tacutu",
"Vadim",
"Fraifeld"
] | ["V J Thannickal, ","J L Schneider, ","R Ziesche, ","M Golec, ","E Samaha, ","S Gulati, ","V J Thann(...TRUNCATED) | ["V","J","J","L","R","M","E","S","V","J","D","C","M","A","L","M","A","L","M","A","M","B","E","V","J"(...TRUNCATED) | ["Thannickal","Schneider","Ziesche","Golec","Samaha","Gulati","Thannickal","Zank","Bueno","Mora","Ro(...TRUNCATED) | ["Aging, antagonistic pleiotropy and fibrotic disease. V J Thannickal, Int. J. Biochem. Cell Biol. 4(...TRUNCATED) | ["16","19","21","15,","21","21,","23","24","25","15","22","27","28","29","6,","27,","30,","31","32,"(...TRUNCATED) | ["Aging, antagonistic pleiotropy and fibrotic disease","The aging lung: Physiology, disease, and imm(...TRUNCATED) | ["the 9th Python in Science Conference 92-96","Int. J. Biochem. Cell Biol","Cell","Biogerontology","(...TRUNCATED) | ["\nFigure 3 .\n3Functional module network of the pulmonary fibrosis-related genes (PFRGs) in lung t(...TRUNCATED) | ["Functional module network of the pulmonary fibrosis-related genes (PFRGs) in lung tissue. The netw(...TRUNCATED) | ["Fig. 1","Fig. 2","Fig. 3a","Figure 1","(Fig. 3b)","Figure 2","(Fig. 4","Fig. 4","(Fig. 4","Fig. 4"(...TRUNCATED) | [] | ["www.nature.com/scientificreports/ two or more manipulations. As seen in Table 2, over 85% of the d(...TRUNCATED) | [] | ["Type of manipulation Number of studies","MiR overexpression 1","Additional models of lung fibrosis(...TRUNCATED) | ["Consistency between bleomycin model and IPF \nNumber of manipulations Percentage (%) \n\nFull \n93(...TRUNCATED) | ["Table 2","(Table 3","(Supplementary Table ST1","(Supplementary Table ST1","Table 1","Supplementary(...TRUNCATED) | ["Systems biology analysis of lung fibrosis-related genes in the bleomycin mouse model","Systems bio(...TRUNCATED) | [
"Scientific Reports |"
] |
3,501,718 | 2022-08-05T22:03:00Z | CCBY | https://academic.oup.com/hmg/article-pdf/25/21/4804/10018079/ddw307.pdf | HYBRID | aeb03017edd17faff128c007ed3ed54e86ada8cc | null | null | null | null | 10.1093/hmg/ddw307 | 2513896837 | 28175300 | 5418736 | "\nSystematic analysis of the gerontome reveals links between aging and age-related diseases\n\n\nMa(...TRUNCATED) | ["In model organisms, over 2,000 genes have been shown to modulate aging, the collection of which we(...TRUNCATED) | ["Maria Fernandes \nIntegrative Genomics of Ageing Group\nInstitute of Ageing and Chronic Disease\nU(...TRUNCATED) | ["Integrative Genomics of Ageing Group\nInstitute of Ageing and Chronic Disease\nUniversity of Liver(...TRUNCATED) | [
"Maria",
"Cen",
"Robi",
"Diogo",
"Ashish",
"Jingwei",
"Harikrishnan",
"Daniel",
"Chenhao",
"Alex",
"João"
] | ["Fernandes","Wan","Tacutu","Barardo","Rajput","Wang","Thoppil","Thornton","Yang","Freitas","Pedro D(...TRUNCATED) | ["C Franceschi, ","M Bonafe, ","S Valensin, ","F Olivieri, ","M De Luca, ","E Ottaviani, ","G De Ben(...TRUNCATED) | ["C","M","S","F","M","E","G","C","M","A","L","M","G","J","P","I","J","P","C","J","R","T","A","D","G"(...TRUNCATED) | ["Franceschi","Bonafe","Valensin","Olivieri","De Luca","Ottaviani","De Benedictis","Lopez-Otin","Bla(...TRUNCATED) | ["Inflamm-aging -An evolutionary perspective on immunosenescence. C Franceschi, M Bonafe, S Valensin(...TRUNCATED) | ["(2)","(3)","(4)","(5)","(7)","(4)","(5)","(8)","(9)","(10)","(11)","(12)","(13)","(14)","(15)","(1(...TRUNCATED) | ["Inflamm-aging -An evolutionary perspective on immunosenescence","Open-minded scepticism: inferring(...TRUNCATED) | ["Cambridge","London, UK","Mol. Cell. Gerontol","The Hallmarks of Aging. Cell","An Introduction to G(...TRUNCATED) | ["\nFigure 1 .\n1Protein-protein interactions between worm aging-related genes. Pro-longevity genes (...TRUNCATED) | ["Protein-protein interactions between worm aging-related genes. Pro-longevity genes are depicted in(...TRUNCATED) | ["(Fig. 1","Fig. S1","Fig. 2A)","Fig. 2A)","(Fig. 3","Fig. 2A)","Fig. S2","(Fig. 2B","Figure 2A","Fi(...TRUNCATED) | [] | ["Aging is a major social and medical challenge of the 21 st century. The most accepted mechanisms o(...TRUNCATED) | [] | ["Introduction","Results","Processes and pathways overrepresented in pro-and anti-longevity genes","(...TRUNCATED) | ["Dataset a \nNum. of \ngenes \n\nAverage \nnum. pubs. \n\nMedian \nnum. pubs. \n\nHuman genome (NCB(...TRUNCATED) | ["Table 1)","Table S6","Table 1","(Table 1)","(Supplementary Materials, Tables S6, S7","(Supplementa(...TRUNCATED) | ["Systematic analysis of the gerontome reveals links between aging and age-related diseases","System(...TRUNCATED) | [] |
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